JPH09327265A - Chewing gum using spice containing menthol and cineole - Google Patents
Chewing gum using spice containing menthol and cineoleInfo
- Publication number
- JPH09327265A JPH09327265A JP8170751A JP17075196A JPH09327265A JP H09327265 A JPH09327265 A JP H09327265A JP 8170751 A JP8170751 A JP 8170751A JP 17075196 A JP17075196 A JP 17075196A JP H09327265 A JPH09327265 A JP H09327265A
- Authority
- JP
- Japan
- Prior art keywords
- chewing gum
- geraniol
- extract
- citronellol
- cineole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 235000015218 chewing gum Nutrition 0.000 title claims abstract description 19
- 229940112822 chewing gum Drugs 0.000 title claims abstract description 14
- WEEGYLXZBRQIMU-UHFFFAOYSA-N Eucalyptol Chemical compound C1CC2CCC1(C)OC2(C)C WEEGYLXZBRQIMU-UHFFFAOYSA-N 0.000 title claims description 10
- 229960005233 cineole Drugs 0.000 title claims description 10
- RFFOTVCVTJUTAD-UHFFFAOYSA-N cineole Natural products C1CC2(C)CCC1(C(C)C)O2 RFFOTVCVTJUTAD-UHFFFAOYSA-N 0.000 title claims description 8
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 title description 6
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 title description 6
- 229940041616 menthol Drugs 0.000 title description 6
- 235000013599 spices Nutrition 0.000 title 1
- GLZPCOQZEFWAFX-UHFFFAOYSA-N Geraniol Chemical compound CC(C)=CCCC(C)=CCO GLZPCOQZEFWAFX-UHFFFAOYSA-N 0.000 claims abstract description 26
- QMVPMAAFGQKVCJ-UHFFFAOYSA-N citronellol Chemical compound OCCC(C)CCC=C(C)C QMVPMAAFGQKVCJ-UHFFFAOYSA-N 0.000 claims abstract description 24
- GLZPCOQZEFWAFX-YFHOEESVSA-N Geraniol Natural products CC(C)=CCC\C(C)=C/CO GLZPCOQZEFWAFX-YFHOEESVSA-N 0.000 claims abstract description 13
- 239000005792 Geraniol Substances 0.000 claims abstract description 13
- 229940113087 geraniol Drugs 0.000 claims abstract description 13
- QMVPMAAFGQKVCJ-SNVBAGLBSA-N (R)-(+)-citronellol Natural products OCC[C@H](C)CCC=C(C)C QMVPMAAFGQKVCJ-SNVBAGLBSA-N 0.000 claims abstract description 12
- JGQFVRIQXUFPAH-UHFFFAOYSA-N beta-citronellol Natural products OCCC(C)CCCC(C)=C JGQFVRIQXUFPAH-UHFFFAOYSA-N 0.000 claims abstract description 12
- 235000000484 citronellol Nutrition 0.000 claims abstract description 12
- 235000021537 Beetroot Nutrition 0.000 claims description 6
- 239000000796 flavoring agent Substances 0.000 claims description 6
- 235000019634 flavors Nutrition 0.000 claims description 6
- 241001122767 Theaceae Species 0.000 claims 2
- 208000035285 Allergic Seasonal Rhinitis Diseases 0.000 abstract description 14
- 208000024891 symptom Diseases 0.000 abstract description 14
- 206010048908 Seasonal allergy Diseases 0.000 abstract description 5
- 244000269722 Thea sinensis Species 0.000 abstract description 5
- 230000001055 chewing effect Effects 0.000 abstract description 4
- 230000003266 anti-allergic effect Effects 0.000 abstract description 3
- 210000003928 nasal cavity Anatomy 0.000 abstract description 2
- 230000002195 synergetic effect Effects 0.000 abstract description 2
- 244000267823 Hydrangea macrophylla Species 0.000 abstract 1
- 235000014486 Hydrangea macrophylla Nutrition 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 230000000694 effects Effects 0.000 description 13
- 241000196324 Embryophyta Species 0.000 description 6
- 206010020751 Hypersensitivity Diseases 0.000 description 5
- 235000012054 meals Nutrition 0.000 description 4
- 210000001519 tissue Anatomy 0.000 description 4
- 235000016068 Berberis vulgaris Nutrition 0.000 description 3
- 241000335053 Beta vulgaris Species 0.000 description 3
- 240000005109 Cryptomeria japonica Species 0.000 description 3
- 208000030961 allergic reaction Diseases 0.000 description 3
- 238000011156 evaluation Methods 0.000 description 3
- 230000004044 response Effects 0.000 description 3
- 239000000341 volatile oil Substances 0.000 description 3
- 206010039101 Rhinorrhoea Diseases 0.000 description 2
- 150000001298 alcohols Chemical class 0.000 description 2
- 208000026935 allergic disease Diseases 0.000 description 2
- 230000007815 allergy Effects 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 230000015556 catabolic process Effects 0.000 description 2
- 229930007050 cineol Natural products 0.000 description 2
- 235000009508 confectionery Nutrition 0.000 description 2
- 239000010648 geranium oil Substances 0.000 description 2
- 235000019717 geranium oil Nutrition 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 239000010666 rose oil Substances 0.000 description 2
- 235000019719 rose oil Nutrition 0.000 description 2
- 206010041232 sneezing Diseases 0.000 description 2
- PVXPPJIGRGXGCY-DJHAAKORSA-N 6-O-alpha-D-glucopyranosyl-alpha-D-fructofuranose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@](O)(CO)O1 PVXPPJIGRGXGCY-DJHAAKORSA-N 0.000 description 1
- 241000218645 Cedrus Species 0.000 description 1
- 241000254173 Coleoptera Species 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
- UNXHWFMMPAWVPI-UHFFFAOYSA-N Erythritol Natural products OCC(O)C(O)CO UNXHWFMMPAWVPI-UHFFFAOYSA-N 0.000 description 1
- 239000004386 Erythritol Substances 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 244000068988 Glycine max Species 0.000 description 1
- 235000010469 Glycine max Nutrition 0.000 description 1
- 206010028735 Nasal congestion Diseases 0.000 description 1
- 206010036790 Productive cough Diseases 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 208000036071 Rhinorrhea Diseases 0.000 description 1
- 235000011449 Rosa Nutrition 0.000 description 1
- 235000004789 Rosa xanthina Nutrition 0.000 description 1
- 241000220222 Rosaceae Species 0.000 description 1
- YWPVROCHNBYFTP-UHFFFAOYSA-N Rubusoside Natural products C1CC2C3(C)CCCC(C)(C(=O)OC4C(C(O)C(O)C(CO)O4)O)C3CCC2(C2)CC(=C)C21OC1OC(CO)C(O)C(O)C1O YWPVROCHNBYFTP-UHFFFAOYSA-N 0.000 description 1
- 206010040914 Skin reaction Diseases 0.000 description 1
- 239000004902 Softening Agent Substances 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 230000007012 clinical effect Effects 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000009429 distress Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- UNXHWFMMPAWVPI-ZXZARUISSA-N erythritol Chemical compound OC[C@H](O)[C@H](O)CO UNXHWFMMPAWVPI-ZXZARUISSA-N 0.000 description 1
- 229940009714 erythritol Drugs 0.000 description 1
- 235000019414 erythritol Nutrition 0.000 description 1
- 239000010642 eucalyptus oil Substances 0.000 description 1
- 229940044949 eucalyptus oil Drugs 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 208000010753 nasal discharge Diseases 0.000 description 1
- 210000002850 nasal mucosa Anatomy 0.000 description 1
- 210000001331 nose Anatomy 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 235000019198 oils Nutrition 0.000 description 1
- 239000007967 peppermint flavor Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
- 206010039083 rhinitis Diseases 0.000 description 1
- YWPVROCHNBYFTP-OSHKXICASA-N rubusoside Chemical compound O([C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O YWPVROCHNBYFTP-OSHKXICASA-N 0.000 description 1
- 230000008786 sensory perception of smell Effects 0.000 description 1
- 230000035483 skin reaction Effects 0.000 description 1
- 231100000430 skin reaction Toxicity 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Abstract
Description
【0001】[0001]
【発明の属する技術分野】本発明は、花粉症症状緩和効
果を有するチューインガム、さらに詳しくは、メントー
ルおよびシネオール含有香料使用チューインガムに関す
る。TECHNICAL FIELD The present invention relates to a chewing gum having a hay fever symptom alleviating effect, and more particularly to a chewing gum containing a menthol and cineol-containing flavor.
【0002】[0002]
【従来の技術】シネオールを含有したユーカリ油、メン
トール等の精油成分は、ヨーロッパ諸国で鼻炎や上気道
炎の治療に伝統的に使われ、また、わが国ではその製剤
が一般総合感冒剤として市販されているが、これらの薬
剤は胸やのどに塗布する外用剤で、皮下吸収および蒸発
成分の吸入によって効果をあらわす。2. Description of the Related Art Essential oils such as eucalyptus oil and menthol containing cineole have been traditionally used for the treatment of rhinitis and upper respiratory tract in European countries, and their preparations are marketed in Japan as general cold remedies. However, these drugs are external preparations that are applied to the chest and throat, and are effective by subcutaneous absorption and inhalation of vaporized components.
【0003】一方、これらメントールおよびシネオール
含有香料使用チューインガムは、噛むことにより、その
成分が吸気とともに鼻腔粘膜に直接作用してアレルギー
反応を軽減させることにより、花粉症に由来するくしゃ
み、鼻汁、鼻閉等の諸症状を緩和することが知られてい
る。On the other hand, these chewing gums containing menthol and cineole-containing flavors have a sneezing, nasal discharge, and nasal congestion caused by hay fever, by chewing the ingredients and acting directly on the nasal mucosa with inhalation to reduce the allergic reaction. It is known to relieve various symptoms such as.
【0004】[0004]
【発明が解決しようとする課題】しかし、その緩和効果
を高めようとして単にメントールおよびシネオールを強
化しても著効例をみることができないことに鑑み、発明
者は、鼻腔内組織の血流を増加しその組織を活発化させ
るチューインガムの咀嚼運動に関連して、上記花粉症症
状緩和の効果を改善させるべく鋭意研究し、それぞれ花
粉症症状緩和作用または抗アレルギー作用があると報告
されている甜茶抽出物,ゲラニオールおよびシトロネロ
ールを複合的に使用することにより、顕著な花粉症症状
緩和効果を得られることを知見し、本発明を完成するに
至った。However, in view of the fact that no remarkable effect can be seen even if menthol and cineol are simply strengthened in order to enhance the relaxation effect, the inventor has found that the blood flow in the tissues in the nasal cavity is In relation to the chewing movement of chewing gum that increases and activates its tissue, intensive research has been conducted to improve the effect of alleviating the above-mentioned symptoms of hay fever, and each has been reported to have a hay fever symptom-relieving effect or antiallergic effect The inventors have found that the combined use of the extract, geraniol and citronellol can achieve a remarkable hay fever alleviation effect, and have completed the present invention.
【0005】[0005]
【課題を解決するための手段】本発明は、メントールお
よびシネオール含有香料使用チューインガムであって、
甜茶抽出物とゲラニオールまたは/およびシトロネロー
ルを含有することを特徴とするものである。SUMMARY OF THE INVENTION The present invention is a flavored chewing gum containing menthol and cineole comprising:
It is characterized in that it contains beet extract and geraniol and / or citronellol.
【0006】上記においては、1食あたり甜茶抽出物が
8〜120mg,ゲラニオールが0.1〜50mg,シトロ
ネロール0.1〜50mgが摂取できるように配合される
ことが好ましく、これによって花粉症症状緩和効果を一
層高めることができる。上記最小値より少ない量では効
果が認められず、最大値より多い量では素材のもつ風味
が強すぎて品質上の問題が生じる。[0006] In the above, it is preferable to mix soybean tea extract of 8 to 120 mg, geraniol of 0.1 to 50 mg, and citronellol of 0.1 to 50 mg per meal, thereby alleviating the hay fever symptoms. Can be further enhanced. If the amount is less than the above-mentioned minimum value, no effect is observed, and if the amount is more than the maximum value, the flavor of the raw material is too strong, which causes quality problems.
【0007】甜茶は、中国広西壮族自治区に植生してい
るバラ科の植物で、その葉にルブソシドと呼ばれる成分
を含有して強い甘味を呈し、食欲増進,去痰,咳止め,
解熱等に効果があるとされ、安全性も確立されている。
本発明の甜茶抽出物としては、その甜茶原料をたとえば
熱水抽出して得たエキスをスプレードライして粉末とし
たものを使用する。[0007] Beetle tea is a plant of the family Rosaceae that is vegetated in Guangxi, China. It contains a component called rubusoside in its leaves and exhibits a strong sweetness. It enhances appetite, expectoration, cough control,
It is said to be effective in reducing fever, and safety is also established.
As the beetroot extract of the present invention, a powder obtained by spray-drying an extract obtained by extracting the beetroot tea material with hot water, for example, is used.
【0008】ゲラニオールは、植物由来アルコール類に
属し、天然にはパロマローザ油,ローズ油,ゼラニウム
油等の多くの植物精油中に存在し、温和でローズ様の甘
い花香調の無色〜淡黄色透明な液体であり、また、シト
ロネロールは、同じく植物由来アルコール類に属し、天
然にはゼラニウム油,ローズ油等の植物精油中に存在
し、温和でローズ様の甘い花香調の無色透明な液体であ
って、これら植物由来の揮発性物質は、一般にアレルギ
ー反応後の収縮等の変化を抑制するとともにアレルギー
反応の発現を抑制するとされている。Geraniol belongs to plant-derived alcohols and is naturally present in many plant essential oils such as Paloma rosa oil, rose oil and geranium oil, and has a mild, rose-like sweet floral fragrance colorless to pale yellow transparent. It is a liquid, and citronellol also belongs to plant-derived alcohols, is naturally present in plant essential oils such as geranium oil and rose oil, and is a mild, rose-like, colorless and transparent liquid with a sweet floral scent. Generally, these plant-derived volatile substances are said to suppress changes such as contraction after an allergic reaction and suppress the development of an allergic reaction.
【0009】[0009]
【実施例】下記により、表1に示す実施例1〜3および
対照品〜の各チューインガムを製造した。ガムベー
スをニーダーに入れ約120℃で溶解撹拌し、それを5
0℃まで冷却したところで混合機に投入し、その混合機
中のガムベースに、砂糖,還元パラチノース,エリスリ
トール,ブドウ糖,軟化剤,メントールおよびシネオー
ル含有ペパーミント香料,甜茶抽出物,ゲラニオール,
シトロネロールを投入し、同50℃で45分間撹拌練成
し、それを、所要の射出成型機によりシート状に押し出
すとともに、圧延し、裁断機により1枚当り3.2gと
した。[Examples] The chewing gums of Examples 1 to 3 and control product shown in Table 1 were produced as follows. Put the gum base in a kneader and melt and stir at about 120 ° C.
After cooling to 0 ° C, the mixture is put into a mixer, and the gum base in the mixer contains sugar, reduced palatinose, erythritol, glucose, a softening agent, menthol- and cineole-containing peppermint flavor, beet extract, geraniol,
Citronellol was charged, and the mixture was stirred and kneaded at 50 ° C. for 45 minutes, extruded into a sheet by a required injection molding machine, rolled, and cut by a cutting machine to 3.2 g per sheet.
【0010】甜茶抽出物,ゲラニオール,シトロネロー
ルの各添加量について、たとえば実施例3を見ると、そ
れぞれ0.20%,0.01%,0.01%であるから
これらを1枚当り3.2gの製品について換算すると、
それぞれ6.4mg,0.32mg,0.32mgとなる。Regarding the added amounts of beetroot extract, geraniol, and citronellol, for example, looking at Example 3, they were 0.20%, 0.01%, and 0.01%, respectively. If you convert the product of
It becomes 6.4 mg, 0.32 mg, and 0.32 mg, respectively.
【0011】[0011]
【表1】 [Table 1]
【0012】[0012]
花粉症患者に対する臨床的効果の評価 a.対照品〜および実施例1〜3のチューインガム
を噛んでもらいその症状緩和効果について確認した。 b.患者は東京都内の某耳鼻咽喉科医院に受診したスギ
花粉症患者161名で、その内訳は、性別は男66名,
女95名、年齢は15〜60才にわたり、平均25.1
才であった。 c.スギ花粉症の診断は、鼻誘発検査,RAST検査,
皮内反応検査の3つのうち2つ以上が陽性の場合とし
た。 d.自覚症状の程度,鼻鏡所見の程度の判定について
は、奥田の基準に準じた(表2,3)。Evaluation of clinical effects on hay fever patients a. The chewing gums of the control products and the chewing gums of Examples 1 to 3 were chewed and their symptom alleviating effects were confirmed. b. The patients were 161 Japanese cedar pollinosis patients who visited a certain otolaryngology clinic in Tokyo. The breakdown was 66 males,
95 women, ages 15-60 years old, average 25.1
I was old. c. Japanese cedar pollinosis is diagnosed by nasal provocation test, RAST test,
Of the three skin reaction tests, two or more were positive. d. The level of subjective symptoms and the level of nasal findings were based on Okuda's criteria (Tables 2 and 3).
【0013】[0013]
【表2】 [Table 2]
【0014】[0014]
【表3】 [Table 3]
【0015】e.スギ花粉症重症度の判定は、表4の判
定基準により、重症,中等症,軽症および無症状の4段
階に分類した。E. The severity of Japanese cedar pollinosis was classified into four stages of severe, moderate, mild and asymptomatic according to the criteria of Table 4.
【0016】[0016]
【表4】 [Table 4]
【0017】f.161名の重症度の内訳は、中等症7
2名,軽症89名と全て中等症以下の患者であった。 g.aの対照品〜および実施例1〜3のチューイン
ガムを2週間以上継続して、1日6枚を、午前3枚で1
食,午後3枚で1食にし、1枚について5分以上の時間
をかけて噛ませて効果の確認を行った。したがって、た
とえば実施例3のチューインガムについて見ると、1食
あたり、甜茶抽出物,ゲラニオール,シトロネロールの
摂取量は、それぞれ19.2mg, 0.96mg, 0.96
mgとなる。F. The breakdown of the severity of 161 persons is moderate 7
There were 2 patients and 89 patients with mild illness, all of which were moderate or less. g. The chewing gum of the control product of a) and the chewing gums of Examples 1 to 3 are continued for 2 weeks or longer, and 6 pieces per day are given at 3 pieces in the morning.
After eating, three meals were made into one meal, and each piece was chewed for 5 minutes or longer to confirm the effect. Therefore, for example, when looking at the chewing gum of Example 3, the intakes of beetroot tea extract, geraniol, and citronellol were 19.2 mg, 0.96 mg, and 0.96 per meal, respectively.
It becomes mg.
【0018】h.効果判定は、鼻鏡所見,アレルギー日
記を総合して、著効,有効,やや有効および不変の4段
階で行った。ここでいうアレルギー日記とは、対照観察
期間開始より毎日、自覚症状(くしゃみ,鼻水,鼻づま
り,嗅覚異常,苦痛の程度等),原因(症状のきっか
け,症状の起きた場所等),摂取状況および随伴症状を
可能な限り患者に記載させたものである。H. Efficacy evaluation was performed on the basis of four grades of excellent response, effective response, moderately effective response, and unchanged, based on nasal findings and allergy diary. The allergy diary mentioned here means subjective symptoms (sneezing, runny nose, stuffy nose, abnormal olfaction, degree of distress, etc.), causes (trigger of symptoms, place of occurrence of symptoms, etc.), intake status every day from the start of the control observation period. And the concomitant symptoms should be described to the patient as much as possible.
【0019】スギ花粉症に対する効果の総合判定は、表
5,6に示すように、やや有効以上を含めた有効率が、
対照品は33.3%,同は34.7%,同は3
0.4%,同は56.1%であったのに対し、実施例
1は85.7%,同2は88.3%,同3は91.6%
であった。As shown in Tables 5 and 6, the overall evaluation of the effect on the cedar pollinosis was as follows.
Control product 33.3%, same 34.7%, same 3
0.4% and 56.1%, respectively, whereas Example 1 had 85.7%, Example 2 had 88.3%, and Example 3 had 91.6%.
Met.
【0020】[0020]
【表5】 [Table 5]
【0021】[0021]
【表6】 [Table 6]
【0022】上の表から明らかなように、メントールお
よびシネオール含有香料使用チューインガムに、甜茶抽
出物とゲラニオールまたは/およびシトロネロールを含
有させると、きわめて顕著な花粉症症状緩和効果が見ら
れるもので、この著効は、チューインガムの咀嚼運動が
鼻腔内組織の血流を増加しその組織を活発化させるの
と、上記各成分の有する花粉症症状緩和作用または抗ア
レルギー作用の複合的または相乗的効果であると推定さ
れる。As is clear from the above table, when the menthol- and cineole-containing flavor-containing chewing gum contains the beet extract and geraniol and / or citronellol, a very remarkable hay fever symptom alleviating effect is observed. Remarkable effect is a complex or synergistic effect of chewing gum chewing movement to increase blood flow in nasal tissues and activate the tissues, and to alleviate hay fever symptoms or antiallergic effects of each of the above components. It is estimated to be.
Claims (2)
シトロネロールを含有することを特徴とするメントール
およびシネオール含有香料使用チューインガム。1. A menthol- and cineole-containing flavor-containing chewing gum, which contains beetroot tea extract and geraniol or / and citronellol.
ラニオールが0.1〜50mg,シトロネロール0.1〜
50mgが摂取できるように配合されていることを特徴と
する請求項1記載のメントールおよびシネオール含有香
料使用チューインガム。2. The amount of beetroot tea extract is 8 to 120 mg, geraniol is 0.1 to 50 mg, and citronellol is 0.1 to 0.1 per serving.
The menthol- and cineole-containing flavor-containing chewing gum according to claim 1, which is formulated so that 50 mg can be ingested.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP17075196A JP3451519B2 (en) | 1996-06-11 | 1996-06-11 | Chewing gum using menthol and cineole containing fragrance |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP17075196A JP3451519B2 (en) | 1996-06-11 | 1996-06-11 | Chewing gum using menthol and cineole containing fragrance |
Publications (2)
Publication Number | Publication Date |
---|---|
JPH09327265A true JPH09327265A (en) | 1997-12-22 |
JP3451519B2 JP3451519B2 (en) | 2003-09-29 |
Family
ID=15910721
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP17075196A Expired - Fee Related JP3451519B2 (en) | 1996-06-11 | 1996-06-11 | Chewing gum using menthol and cineole containing fragrance |
Country Status (1)
Country | Link |
---|---|
JP (1) | JP3451519B2 (en) |
Cited By (7)
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---|---|---|---|---|
EP1031348A3 (en) * | 1999-02-22 | 2001-03-21 | Kao Corporation | Interleukin-4 production inhibitors |
EP1545448A4 (en) * | 2002-08-27 | 2005-12-14 | Wrigley W M Jun Co | Breath freshening and oral cleansing product using geraniol |
JP2006342188A (en) | 2006-09-28 | 2006-12-21 | Rohto Pharmaceut Co Ltd | Intraoral dissolution type or chewable solid internal medicine composition for treating rhinitis |
JP2007161679A (en) * | 2005-12-16 | 2007-06-28 | Kao Corp | Pollen allergosis-mitigating composition |
JPWO2006129876A1 (en) * | 2005-05-31 | 2009-01-08 | クラシエフーズ株式会社 | Body odor improving agent for ingestion into body, food and drink using the same, and body odor improving method |
WO2009103428A1 (en) * | 2008-02-19 | 2009-08-27 | Südzucker Aktiengesellschaft Mannheim/Ochsenfurt | Improved confectionery aroma containing products |
JP2013032408A (en) * | 2012-11-22 | 2013-02-14 | Rohto Pharmaceutical Co Ltd | Orally dissolution type or mandibulate type rhinitis treatment solid internal pharmaceutical formulation |
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1996
- 1996-06-11 JP JP17075196A patent/JP3451519B2/en not_active Expired - Fee Related
Cited By (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1031348A3 (en) * | 1999-02-22 | 2001-03-21 | Kao Corporation | Interleukin-4 production inhibitors |
EP1545448A4 (en) * | 2002-08-27 | 2005-12-14 | Wrigley W M Jun Co | Breath freshening and oral cleansing product using geraniol |
JPWO2006129876A1 (en) * | 2005-05-31 | 2009-01-08 | クラシエフーズ株式会社 | Body odor improving agent for ingestion into body, food and drink using the same, and body odor improving method |
JP2013056910A (en) * | 2005-05-31 | 2013-03-28 | Kracie Foods Ltd | Body odor improving agent for ingestion into body, beverage/food using the same, and method for improving body odor |
JP2015221792A (en) * | 2005-05-31 | 2015-12-10 | クラシエフーズ株式会社 | Body odor improving agent for ingestion into body, beverage/food using the same, and method for improving body odor |
JP5890083B2 (en) | 2005-05-31 | 2016-03-22 | クラシエフーズ株式会社 | Body odor improving agent for ingestion in body, food and drink using the same, and method for improving body odor |
JP2018138043A (en) * | 2005-05-31 | 2018-09-06 | クラシエフーズ株式会社 | Body odor improvement agent for ingestion into body, and food and drink, and body odor improvement method using the same |
JP2007161679A (en) * | 2005-12-16 | 2007-06-28 | Kao Corp | Pollen allergosis-mitigating composition |
JP2006342188A (en) | 2006-09-28 | 2006-12-21 | Rohto Pharmaceut Co Ltd | Intraoral dissolution type or chewable solid internal medicine composition for treating rhinitis |
WO2009103428A1 (en) * | 2008-02-19 | 2009-08-27 | Südzucker Aktiengesellschaft Mannheim/Ochsenfurt | Improved confectionery aroma containing products |
EA018096B1 (en) * | 2008-02-19 | 2013-05-30 | Зюдцукер Акциенгезелльшафт Маннхайм/Окзенфурт | Confectionery aroma containing products and processes to obtain them |
JP2013032408A (en) * | 2012-11-22 | 2013-02-14 | Rohto Pharmaceutical Co Ltd | Orally dissolution type or mandibulate type rhinitis treatment solid internal pharmaceutical formulation |
Also Published As
Publication number | Publication date |
---|---|
JP3451519B2 (en) | 2003-09-29 |
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