JPH09276385A - Volatile chemicals controlled releasing device - Google Patents

Abstract

PROBLEM TO BE SOLVED: To prevent excess chemicals discharge to a releasing body according to temperature changes in a volatile chemicals controlled releasing device. SOLUTION: This controlled releasing device consists of a reverse standing container 2 which is containing liquid aromatic (A) and is directing a port part 2a downward and is almost sealed air-tight, a volatilizing paper 3 installed under the port part 2a and a supplier 10 to supply the liquid aromatic (A) to the volatilizing paper 3. In this case, a transformable diaphragm which transforms following to atmospheric pressure changes of an upper space 9 over liquid surface caused by verying temperature is integrally built in the container 2 in a top sectioin of the container 2.

Description

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The present invention relates to a volatile drug releaser.

[0002]

2. Description of the Related Art Conventionally, as a volatile drug sustained-release device, a substantially sealed container for accommodating a liquid drug and having a mouth portion facing downward, and a volatilizer disposed at a position below the mouth portion, There is known one provided with a supply body for supplying the drug in the container to the volatilization body through the mouth portion.

This type of release device is generally called an inverted type, and like the upright type with its mouth facing upward,
It is widely used in general. As conventional examples of the inverted type sustained-release device, there are No. 1-93039 and No. 61-39.
No. 82637, No. 61-194536, No. 6
No. 1-194537, No. 61-194538, No. 56-6444, No. 63-135644, etc.

Usually, this type of inverted volatilizable drug sustained-release device transfers a drug from a feeder located at the bottom of the container to a volatilizer below the container. Compared to an upright type that sucks up the drug, the drug is better supplied to the volatilizer via the feeder, and the inflow of air into the container due to the decrease in the drug is smoother. Is excellent in.

[0005]

However, in the conventional inverted type volatile drug sustained-release device, as described above, while air can be easily introduced into the container, the gas (air Since it is difficult to discharge the amount of chemicals and the amount of evaporated chemicals), when the temperature rises in the summer and the atmospheric pressure in the upper space of the container rises, the gas in this upper space pushes more chemicals than usual through the feeder. May be discharged to the volatilizer. In that case, there arises inconveniences such as a chemical such as an aromatic agent being diffused into the atmosphere more than necessary, and the consumption of the chemical is extremely fast. For this reason, there has been a strong demand for the development of a volatile drug sustained-release device that sufficiently considers the ambient temperature change.

The present invention has been made in view of the above-mentioned conventional problems, and provides a volatile drug sustained-release device for surely preventing excessive discharge of a drug to a volatile substance due to a change in ambient temperature. The purpose is to do.

[0007]

The present invention has the following configuration to achieve the above object. The invention according to claim 1 is a substantially sealed inverted container for containing a liquid drug therein and having a mouth portion facing downward, a volatilizer disposed below the mouth portion, In a volatile drug sustained-release device provided with a supply body for supplying the drug in a container to the volatile substance, the container is deformed in response to a pressure change in an upper space above the liquid surface due to a temperature change. The volatile drug releaser is characterized in that a deforming portion for maintaining a constant atmospheric pressure in the container is provided.

A second aspect of the present invention is the volatile drug releaser according to the first aspect, wherein the deformable portion is integrally formed on the upper end portion of the container.

The invention of claim 3 is characterized in that the deformable portion is formed integrally with the upper end portion of the container and has a bellows shape. It is a vessel.

According to a fourth aspect of the invention, the upper end of the container is
2. The volatile drug releaser according to claim 1, wherein the volatile drug releaser is opened to an upper space above the liquid surface, and the deformed portion is fixed to an upper end portion of the container.

According to a fifth aspect of the present invention, the supply body is a porous sintered body made of a polyolefin resin, or an injection molded product having through holes formed in the vertical direction. It is a volatile drug releaser.

According to the present invention, when the temperature rises in summer and the atmospheric pressure in the upper space in the container rises, the gas (air and evaporated chemicals) in the upper space pushes up the deformed portion. , The volume of gas in the headspace increases. As a result, the gas in the upper space is kept at normal pressure without being affected by the ambient temperature change. Therefore, according to the present invention, it is possible to reliably prevent the excessive discharge of the drug to the volatilization body due to the temperature change.

Further, the drug in the container is supplied to the volatilization body through the supply body, whereby the drug is saturated inside the supply body and the volatilization body. Then, in accordance with the volatilization of the drug in the volatilizer, the drug in the container is replenished to the volatilizer via the supplier, so that the drug in the container is gradually released into the atmosphere as in the conventional case.

[0014]

BEST MODE FOR CARRYING OUT THE INVENTION Embodiments of the present invention will be described below with reference to the drawings. In this embodiment, the volatile drug sustained-release device of the present invention is applied to a liquid fragrance sustained-release device.

(First Embodiment) As shown in FIGS. 1 and 2, the liquid fragrance sustained-release apparatus 1 of the first embodiment contains a liquid fragrance (an example of a liquid medicine) A therein, And, a substantially sealed inverted container 2 with the mouth 2a facing downward,
It is provided with a volatilization paper (corresponding to a volatilization body) 3 arranged below the mouth portion 2a, and a supply body 10 for supplying the liquid aromatic agent A in the container 2 to the volatilization paper 3.

The liquid fragrance sustained-release device 1 also has a pedestal 5 having a volatilized paper 3 on its upper surface, a pedestal 5 fitted around the pedestal 5 to support the container 2 and a plurality of window holes 6a. It includes a cover 6, a lower cap 7 that is screwed into the mouth 2a from below and is fitted into a recess 6b in the center of the cover 6 from above, and an upper cap 8 that is fitted into the upper end of the container 2. .

Then, in the first embodiment, the upper end of the container 2 is deformed in response to a change in atmospheric pressure in the upper space 9 above the liquid surface due to a change in temperature to maintain the atmospheric pressure in the container 2 constant. The deformable film (corresponding to the deformed portion) 4 is integrally formed. The thickness of the deformable film 4 is in the range of 0.01 to 0.1 mm, while the thickness of the container 2 is in the range of 0.5 to 1 mm. A vent hole 8a is formed through the upper cap 8 in order to deform the deformable film 4 in accordance with a change in atmospheric pressure in the upper space 9 above the liquid surface due to a change in temperature.

The configuration of each section will be described in detail below. As shown in FIG. 2, the container 2 is a molded product made of synthetic resin such as polyethylene or polypropylene, and is procured by blow molding, for example. The mouth portion 2a of the container 2 is formed to have a smaller diameter than the body portion, and a male screw portion that is screwed into a female screw on the inner circumference of the lower cap 7 is provided on the outer circumference thereof. A circular hole 7a is formed in the center of the bottom of the lower cap 7 so that the substantially convex supply member 10 can be projected.

The cover 6 is provided with a concave portion 6b which is open upward and accommodates the mouth portion 2a and the lower cap 7, and the lower cap 7 is provided at the center of the bottom portion of the concave portion 6b.
The circular hole 6b1 having a diameter larger than that of the circular hole 7a is formed. Further, a tapered slope 6b2 that expands upward is formed at the upper edge of the recess 6b.
A taper-shaped step portion 2b formed in the lower portion of the container 2 is supported by the container 2.

Further, the supply member 10 is not particularly limited as long as it has a liquid absorbing property.
Examples include porous sintered bodies, foams, pulps and the like. In addition,
When comparing the porous sintered body and the foamed body, the porous sintered body is preferable because the porosity can be easily adjusted.

The porous sintered body is prepared by sintering thermoplastic resin powder. Examples of the thermoplastic resin include polyethylene, polypropylene, ethylene / butene-1 copolymer, ethylene / 4-methylpentene-1 copolymer, ethylene / vinyl acetate copolymer and other polyolefins, polystyrene, acrylonitrile / styrene copolymer. , Acrylonitrile / butadiene / styrene copolymer, polycarbonate, polymethylmethacrylate, polyamide, polyester, polyphenylene oxide, polyacrylonitrile, polyvinyl chloride, polyvinylidene chloride and the like. Among them, a polyolefin resin is desirable because it has excellent chemical resistance, does not cause dimensional change due to water absorption, does not cause strength reduction due to water absorption, and has sufficient strength as a sintered compact.

As shown in FIG. 2, the volatilized paper 3 is laid on the upper surface of the bottom portion of the pedestal 5 according to the inner shape of the pedestal 5. Examples of the volatile paper 3 include porous materials such as porous sintered bodies and foams, filter paper, and the like, but are not particularly limited as long as they have liquid absorbability.

According to the first embodiment having the above structure, the following actions and effects can be obtained. The liquid fragrance A in the container 2 is supplied to the volatilization paper 3 through the liquid absorbent supply body 10. As a result, the liquid fragrance A is saturated inside the supply body 10 and the volatile paper 3. The liquid fragrance A in the container 2 is supplied to the volatile paper 3 via the supply body 10 at any time in accordance with the volatilization of the liquid fragrance A in the volatile paper 3. , Through the window 6a of the cover 6, as in the conventional case, is gradually released into the atmosphere.

Then, when the atmospheric pressure in the upper space 9 in the container 2 increases due to an increase in temperature, the gas (air and evaporated fragrance) in the upper space 9 is integrally formed on the upper end of the container 2. The deformable film 4 is pushed up and deformed. As a result, the volume of the upper space 9 is increased, and the gas in the upper space 9 is maintained at normal pressure without being affected by the ambient temperature change. Therefore, according to the first embodiment, it is possible to reliably prevent the excessive discharge of the liquid aromatic agent A to the volatilization paper 3 due to the temperature change.

(Second Embodiment) Next, the liquid fragrance sustained-release device of the second embodiment will be described. In addition, about the same structure as the liquid fragrance | flavor extended release device of 1st Embodiment, the same code | symbol as 1st Embodiment is attached | subjected and description is abbreviate | omitted.

The liquid fragrance sustained-release device 11 of the second embodiment is
As shown in FIG. 3, in the basic configuration of the first embodiment, the inside of the container 2 is deformed at the upper end of the container 2 in response to a change in atmospheric pressure in the upper space 9 above the liquid surface due to a temperature change. The deformable film 14 that maintains a constant atmospheric pressure is integrally molded, and the deformable film 14 has a bellows shape. The film thickness of the deformable film 14 is in the range of 0.01 to 0.1 mm.

According to the second embodiment having the above-mentioned structure, when the atmospheric pressure in the upper space 9 in the container 2 increases due to an increase in temperature, the gas in the upper space 9 (air and evaporated fragrance agent) is increased. ) Pushes up the deformable film 14 having a bellows shape integrally formed on the upper end of the container 2 to deform it.
As a result, the volume of the upper space 9 is increased, and the gas in the upper space 9 is maintained at normal pressure without being affected by the ambient temperature change. Therefore, according to the second embodiment, it is possible to reliably prevent the excessive discharge of the liquid fragrance agent A onto the volatilization paper 3 due to the temperature change, and the same actions and effects as those of the first embodiment can be obtained. .

(Third Embodiment) Next, a third embodiment will be described. In addition, about the same structure as the liquid fragrance | flavor extended release device of 1st Embodiment and 2nd Embodiment, the same code | symbol is attached | subjected and description is abbreviate | omitted.

The liquid fragrance sustained-release device 21 of the third embodiment is
As shown in FIG. 4, in the basic configuration of the first embodiment, the upper end of the container 2 is opened to the upper space 9 above the liquid surface, and the outer peripheral upper end of the container 2 is affected by temperature change. The deformation film 24, which deforms in response to changes in atmospheric pressure in the upper space 9 above the liquid surface and maintains the atmospheric pressure in the container 2 constant, is heat-sealed and / or bonded. The film thickness of the deformable film 24 is in the range of 0.01 to 0.1 mm, and examples of the material thereof include natural rubber, synthetic rubber, polyethylene film and the like. There is no problem even if the deformation film 24 is heat-sealed and / or adhered to the upper end of the inner periphery of the container 2.

Further, in the third embodiment, the supply body 20 is used, and the supply body 20 has a penetrating liquid for supplying the liquid fragrance A in the container 2 to the volatilization paper 3 at the substantially central portion thereof. It has a supply small hole 22. In addition, this supply body 20
Is preferably an injection-molded product of a thermoplastic or thermosetting resin from the viewpoint of production. The inner diameter of the liquid supply small hole 22 of the supply body 20 is in the range of 0.1 to 1.0 mm.

According to the third embodiment having such a configuration, when the atmospheric pressure in the upper space 9 in the container 2 increases due to an increase in temperature, the gas (air and evaporated fragrance) in the upper space 9 is increased. Causes the deformation film 24 fused and / or adhered to the upper end of the outer periphery of the container 2 to be pushed up and deformed. As a result, the volume of the upper space 9 is increased, and the gas in the upper space 9 is maintained at normal pressure without being affected by the ambient temperature change. Therefore, according to the third embodiment, it is possible to reliably prevent the excessive discharge of the liquid fragrance agent A to the volatilization paper 3 due to the temperature change, and the same operation as in the first and second embodiments. It is possible to obtain the effect.

In the first and second embodiments, the liquid-absorbent supply body 10 is used. However, the liquid-supplying material 10 used in the third embodiment is used and the liquid supply is small. It may be replaced with the supply body 20 having the holes 22, and conversely, the supply body 10 having the liquid absorbing property may be used in the third embodiment.

The liquid fragrance A used in the liquid fragrance sustained release devices 1, 11, and 21 of the first to third embodiments is not particularly limited, and is mainly a fragrance, a surfactant, a solvent and It is obtained by mixing water in an appropriate composition ratio.
In addition, when preparing the liquid fragrance | flavor A with the said component, you may mix | blend arbitrary components as needed. Examples of the optional components include dyes, ultraviolet absorbers, deodorants, preservatives and the like.

As described above, the fragrance used for the preparation of the liquid fragrance A is not particularly limited, and can be appropriately selected from natural fragrances and synthetic fragrances. Examples of natural flavors include orange oil, lemon oil, lime oil, petitgrain oil, yuzu oil, neroli oil, bergamot oil, lavender oil, lapandin oil, abies oil, bay oil, poadrose oil, ylang-ylang oil, citronella oil,
Geranium oil, peppermint oil, peppermint oil, spearmint oil, eucalyptus oil, lemongrass oil, patchouli oil, jasmine oil, rose oil, cedar oil, vetiver oil, galpanum oil, oak moss oil, pine oil, camphor oil, cabbage oil, Essential oils such as scented oil, turpentine oil, clove oil, clove sleeve oil, cassia oil, nutmeg oil, cananga oil, thyme oil, and animal flavors such as musk, spirit cat incense, raccoon incense, and spicy aroma are used.

Examples of synthetic fragrances include linalool, linalyl acetate, geraniol, citronellol, C _{4 to} C ₁₂ various aliphatic aldehydes, phenylethyl alcohol, benzyl acetate, geranyl acetate, geranyl formate, vanillin, nitromusks, Galaxolide, tonalide, pentalide, Santarex, amyl salicylate, amyl acetate, γ-
Undecalactone, ethyl methylphenylglycidate,
Heliotrobin and the like. These fragrances may be used alone or as a mixed fragrance prepared by mixing two or more kinds.

Surfactants are roughly classified into nonionic surfactants, anionic surfactants and cationic surfactants. Nonionic surfactants include polyoxyethylene alkyl ether and polyoxyethylene. Alkyl phenyl ether, polyoxyethylene fatty acid ester, polyoxyethylene hydrogenated castor oil, and the like, and particularly, the average addition mole number of ethylene oxide is 1 to 30, preferably 5 to 2.
The polyoxyethylene-based nonionic surfactant of 5 can be preferably used. Also, alkylamine oxide and the like can be used. Examples of the anionic surfactant include alkyl sulfate, alkylbenzene sulfonate, polyoxyethylene alkyl ether sulfate, polyoxyethylene alkyl phenyl ether sulfate, polyoxyethylene alkyl phenyl ether sulfonate, and the like. Oxyethylene alkylphenyl ether sulfate and polyoxyethylene alkylphenyl ether sulfonate are preferable. Further, examples of the cationic surfactant include alkyl trimethyl ammonium salt and polyoxyethylene alkyl trimethyl ammonium salt. These surfactants may be used alone or in combination of two or more kinds.

Finally, as the solvent, ethanol, propanol, ethylene glycol, propylene glycol, butylene glycol, hexylene glycol, dipropylene glycol, ethylene glycol monoethyl ether, propylene glycol monomethyl ether, propylene glycol monoethyl ether, dipropylene. Examples include glycol monomethyl ether, dipropylene glycol monoethyl ether, 3-methoxy-3-methylbutanol, isoparaffin, dipentene and the like.

[0038]

EXAMPLES Next, the liquid fragrance A to be filled in the liquid fragrance sustained release devices 1, 11, and 21 of the present embodiment was mixed and prepared in various composition ratios as described below according to the examples. (Example 1) Perfume 2% by weight Polyoxyethylene alkyl ether 2 Polyoxyethylene hydrogenated castor oil 1 Ethanol 5 BHT trace Yellow No. 1 trace water balance Total 100

[0039] (Example 2) Perfume 1 wt% alkylphenol ethoxylate 1.5 Sodium alkyl benzene sulfonate 0.5 Ethanol 3 dihydroxybenzophenone trace Green No. 201 trace water Balance Total 100.0

[0040] (Example 3) Perfume 10 wt% ethanol 20 3-methoxy 3-methyl-butanol 40 BHT trace Green No. 201 trace water balance Total 100

(Example 4) Fragrance 6% by weight Propylene glycol 10 Isoparaffin 40 BHT Trace amount Red No. 106 Trace amount 3-methoxy-3-methylbutanol Total residual amount 100

The liquid fragrances obtained in the above Examples 1 to 4 were filled in the liquid fragrance sustained release devices 1, 11 and 21 which are the embodiments of the volatile drug sustained release device according to the present invention, and the changes with time were performed. As a result of observation, it was confirmed that the temperature decreased by a certain amount at every predetermined time without being affected by the temperature change around the container 2.

[0043]

As described above, according to the present invention, in the volatile drug sustained-release device, it is possible to reliably prevent the excessive drug from being discharged to the volatile substance due to the temperature change.

[Brief description of drawings]

FIG. 1 is a perspective view of a liquid fragrance sustained-release device according to a first embodiment.

FIG. 2 is a vertical cross-sectional view of the liquid fragrance sustained releaser according to the first embodiment.

FIG. 3 is a vertical cross-sectional view of a liquid fragrance sustained-release device according to a second embodiment.

FIG. 4 is a vertical cross-sectional view of a liquid fragrance sustained-release device according to a third embodiment.

[Explanation of symbols]

 1 Liquid fragrance sustained release device (an example of volatile drug sustained release device) 2 Container 2a Mouth part 3 Volatile paper (equivalent to volatile substance) 4 Deformation film (equivalent to deformation part) 9 Upper space 10 Supplyer A Liquid fragrance

Claims (5)

[Claims] 1. A substantially sealed inverted container for containing a liquid drug therein and having a mouth portion facing downward, a volatilizer disposed below the mouth portion, and the inside of the container. In the volatile drug sustained-release device provided with a supplier for supplying the drug to the volatile substance, the container is deformed in response to a pressure change in an upper space above the liquid surface due to a temperature change. A volatile chemical decontamination device, characterized in that a deformable portion for maintaining a constant atmospheric pressure is provided. 2. The volatile drug releaser according to claim 1, wherein the deformable portion is formed integrally with the upper end portion of the container. 3. The volatile drug releaser according to claim 1, wherein the deformable portion is formed integrally with an upper end portion of the container and has a bellows shape. 4. The upper end of the container opens to an upper space above the liquid surface, and the deformable portion is fixed to the upper end of the container. Volatile drug release device. 5. The volatile chemical release according to claim 1, wherein the supply body is a porous sintered body made of a polyolefin resin or an injection molded product having through holes formed in the vertical direction. vessel.