JPH09276387A - Volatile chemicals controlled releasing device - Google Patents

Abstract

PROBLEM TO BE SOLVED: To prevent excess chemicals discharge to a releasing body according to temperature changes, by constituting a supply body by a matter capable of supplying chemicals in a soft package to the releasing body without replacing air. SOLUTION: A high density impregnation body 4 is formed by a liquid absorptive matter capable of supplying a liquid flavor chemical in a soft package 10 to a releasing paper 3 without replacing air. The lower end part of the high density impregnation body 4 is brought in contact with a dent part 3a of the releasing paper 3 through each circular holes 7a and 6b1 of a lower cap 7 and a dent part 6b, The upper end part is protruded in a liquid flavoring agent A. The density of the high density impregnation body 4 is preferable to be not lower than 0.6g/cm<3> , and highly, compressed pulp, etc., is used as the material. By this constitution, since outer sir does not penetrate through the high density impregnation body 4 into the soft package 10 even if the atmospheric temperature elevates, the temperature change does not affect on the action and excess discharging is prevented.

Description

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The present invention relates to a volatile drug releaser.

[0002]

2. Description of the Related Art Conventionally, as a volatile drug sustained-release device, a substantially sealed container for accommodating a liquid drug and having a mouth portion facing downward, and a volatilizer disposed at a position below the mouth portion, It is known that the container is provided with a liquid-supplying supplier that supplies the drug in the container to the volatilizer through the mouth.

This type of release device is generally called an inverted type, and like the upright type with its mouth facing upward,
It is widely used in general. As conventional examples of the inverted type sustained-release device, there are No. 1-93039 and No. 61-39.
No. 82637, No. 61-194536, No. 6
No. 1-194537, No. 61-194538, No. 56-6444, No. 63-135644, etc.

Usually, this type of inverted volatilizable drug sustained-release device transfers a drug from a feeder located at the bottom of the container to a volatilizer below the container. Compared to an upright type that sucks up the drug, the drug is better supplied to the volatilizer via the feeder, and the inflow of air into the container due to the decrease in the drug is smoother. Is excellent in.

[0005]

However, in the conventional inverted type volatile drug sustained-release device, as described above, while air can be easily introduced into the container, the gas (air Since it is difficult to discharge the amount of chemicals and the amount of evaporated chemicals), when the temperature rises in the summer and the atmospheric pressure in the upper space of the container rises, the gas in this upper space pushes more chemicals than usual through the feeder. May be discharged to the volatilizer. In that case, there arises inconveniences such as a chemical such as an aromatic agent being diffused into the atmosphere more than necessary, and the consumption of the chemical is extremely fast. For this reason, there has been a strong demand for the development of a volatile drug sustained-release device that sufficiently considers the ambient temperature change.

The present invention has been made in view of the above-mentioned conventional problems, and provides a volatile drug sustained-release device for surely preventing excessive discharge of a drug to a volatile substance due to a change in ambient temperature. The purpose is to do.

[0007]

The present invention has the following configuration to achieve the above object. According to the invention of claim 1, a flexible soft packaging body filled with a liquid medicine and having a discharging portion facing downward, a container for accommodating the soft packaging body inside, and a position below the discharging portion. In a volatile drug sustained-release device provided with a volatilizer disposed and a liquid absorbent supplier for supplying the drug in the soft package to the volatilizer, the supplier is accompanied by air displacement. It is a volatile chemical | medical agent release device characterized by supplying the chemical | medical agent in the said soft package body to the said volatilization body instead.

The invention according to claim 2 is the volatile chemical releaser according to claim 1, characterized in that the supply body is a high-density impregnated body having a density of 0.6 g / cm ³ or more. .

According to the present invention, even if the temperature rises in summer or the like, the drug in the soft package is supplied to the volatilization body through the supply body without air displacement, so that it is accompanied by a change in ambient temperature. It is possible to reliably prevent the excessive discharge of the drug to the volatilization body. That is, only the amount of drug in the soft package is reduced, and air does not flow into the soft package, so that pressure change is not caused by temperature change in the soft package and is affected by temperature change. Instead, an appropriate amount of drug is supplied to the volatilizer.

Further, as described above, the drug in the soft package is supplied to the volatilization body through the supply body without air replacement, and the drug is saturated inside the supply body and the volatilization body. Then, according to the volatilization of the drug in the volatilizer, the drug in the soft package is replenished to the volatilizer via the supplier, so that the drug in the soft package is the same as in the conventional case.
It is gradually released into the atmosphere.

[0011]

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS An embodiment of the present invention will be described below with reference to the drawings. In this embodiment, the volatile drug sustained-release device of the present invention is applied to a liquid fragrance sustained-release device.

The liquid fragrance sustained release device 1 of this embodiment is shown in FIG.
As shown in FIG. 2 and FIG. 2, a liquid fragrance (an example of a liquid medicine) A is filled without a gap, and a flexible wrapping body 10 having flexibility with the discharge part 9 facing downward, and this soft wrapping body 10 are provided.
A container 2 for accommodating the inside thereof, a volatilization paper (corresponding to a volatilization body) 3 arranged below the discharge part 9, and a volatilization paper for the liquid aromatic agent A in the soft packaging body 10 without air replacement. 3 and a high-density impregnated body (corresponding to a supply body) 4 having a liquid absorbing property to be supplied to 3.

The liquid fragrance gradual release device 1 also has a pedestal 5 having a volatilized paper 3 on its upper surface, a pedestal 5 fitted around the pedestal 5 to support the container 2 and a plurality of window holes 6a. The cover 6, the lower cap 7 that is screwed into the mouth 2a of the container 2 from below, and is fitted into the recess 6b in the central portion of the cover 6 from above, and the upper cap 8 that is fitted into the upper end of the container 2 With. In addition, the upper end of the container 2 is opened so that the soft package 10 can be easily refilled.

In this embodiment, as shown in FIG. 3, the liquid fragrance A is filled in the container 2 without any space, and the container 2 is fitted into the cylindrical discharge portion 9 provided at one end. The soft packaging body 10 including the high-density impregnated body 4 is housed. Details of the soft package 10 and the high-density impregnated body 4 will be described later. The upper cap 8 is filled with air so that the gas in the closed space formed by fitting the upper cap 8 into the container 2 does not change its pressure under the influence of temperature change. Vent hole 8a that flows in and out
Is provided.

The structure of each section will be described in detail below. As shown in FIG. 2, the container 2 is a synthetic resin molded product, and is procured by blow molding, for example. The mouth portion 2a of the container 2 is formed to have a smaller diameter than the body portion, and a male screw portion that is screwed into a female screw on the inner circumference of the lower cap 7 is provided on the outer circumference thereof. A circular hole 7 a having a diameter larger than that of the high density impregnated body 4 is formed in the center of the bottom portion of the lower cap 7.

The cover 6 is provided with a concave portion 6b which is open upward and accommodates the mouth portion 2a and the lower cap 7, and the lower cap 7 is provided at the center of the bottom portion of the concave portion 6b.
The circular hole 6b1 having a diameter larger than that of the circular hole 7a is formed. Further, a tapered slope 6b2 that expands upward is formed at the upper edge of the recess 6b.
A taper-shaped step portion 2b formed in the lower portion of the container 2 is supported by the container 2.

As shown in FIGS. 2 and 3, the soft package 10 is a bag-shaped molded product made of a flexible synthetic resin or a film formed by laminating and / or vapor depositing a synthetic resin and aluminum or silicon oxide. It is procured by ordinary bag-making technology or blow molding. In addition, a discharge portion 9 having a cylindrical shape for fitting the high-density impregnated body 4 is attached to one end of the soft packaging body 10.

As shown in FIG. 2, the high-density impregnated body 4 is fitted into the discharge portion 9 of the soft packaging body 10, and the lower end portion thereof has circular holes 7a in the lower cap 7 and the concave portion 6b, respectively. 6
penetrate b1. The lower end of the high-density impregnated body 4 is a volatile paper 3
Is in contact with the concave portion 3a provided in the central portion of the. The upper end of the high-density impregnated body 4 projects into the liquid fragrance A.

The high-density impregnated body 4 may be any as long as it has a liquid absorbing property and supplies the liquid fragrance A in the soft package 10 to the volatilization paper 3 without air replacement. It is desirable that the density is 0.6 g / cm ³ or more. As the material of the high-density impregnated body 4, high compression pulp,
Examples include cotton, porous sintered bodies, ceramics, and the like.

The porous sintered body is prepared by sintering thermoplastic resin powder. Examples of the thermoplastic resin include polyethylene, polypropylene, ethylene / butene-1 copolymer, ethylene / 4-methylpentene-1 copolymer, ethylene / vinyl acetate copolymer and other polyolefins, polystyrene, acrylonitrile / styrene copolymer. , Acrylonitrile / butadiene / styrene copolymer, polycarbonate, polymethylmethacrylate, polyamide, polyester, polyphenylene oxide, polyacrylonitrile, polyvinyl chloride, polyvinylidene chloride and the like. Among them, a polyolefin resin is desirable because it has excellent chemical resistance, does not cause dimensional change due to water absorption, does not cause strength reduction due to water absorption, and has sufficient strength as a sintered compact.

As shown in FIG. 2, the volatilized paper 3 is laid on the upper surface of the bottom of the pedestal 5 according to the inner shape of the pedestal 5. Examples of the volatilization paper 3 include porous materials such as porous sintered bodies and foams, filter papers, and the like, but are not particularly limited as long as they have liquid absorbability.

According to the above embodiment having the above-mentioned structure, the following actions and effects can be obtained. Flexible package 1
The liquid fragrance A in 0 passes through the high-density impregnated body 4 and is supplied to the volatile paper 3 without air substitution. As a result, the liquid fragrance A is stored inside the high-density impregnated body 4 and the volatile paper 3.
Saturates. Then, in accordance with the volatilization of the liquid fragrance A in the volatile paper 3, the liquid fragrance A in the soft packaging body 10 is replenished to the volatile paper 3 via the high-density impregnation body 4 at any time,
The liquid fragrance agent A in the high-density impregnated body 4 is the window hole 6 of the cover 6.
Through a, it is gradually released into the atmosphere as in the conventional case.

Even if the temperature rises, the outside air does not enter the soft packaging body 10 through the high-density impregnated body 4 and the amount of the liquid fragrance A in the high-density impregnated body 4 gradually increases. It only decreases to. Therefore, according to the above-described embodiment, it is possible to reliably prevent the excessive discharge of the liquid fragrance A to the volatilization paper 3 due to the temperature change.

The liquid fragrance A used in the liquid fragrance sustained release device 1 of the above embodiment is not particularly limited,
It is mainly obtained by blending a fragrance, a surfactant, a solvent and water in an appropriate composition ratio. In addition, when preparing the liquid fragrance | flavor A with the said component, you may mix | blend arbitrary components as needed. Examples of the optional components include dyes, ultraviolet absorbers, deodorants, preservatives and the like.

As described above, the fragrance used for preparing the liquid fragrance A is not particularly limited, and can be appropriately selected from natural fragrances and synthetic fragrances. Examples of natural flavors include orange oil, lemon oil, lime oil, petitgrain oil, yuzu oil, neroli oil, bergamot oil, lavender oil, lapandin oil, abies oil, bay oil, poadrose oil, ylang-ylang oil, citronella oil,
Geranium oil, peppermint oil, peppermint oil, spearmint oil, eucalyptus oil, lemongrass oil, patchouli oil, jasmine oil, rose oil, cedar oil, vetiver oil, galpanum oil, oak moss oil, pine oil, camphor oil, cabbage oil, Essential oils such as scented oil, turpentine oil, clove oil, clove sleeve oil, cassia oil, nutmeg oil, cananga oil, thyme oil, and animal flavors such as musk, spirit cat incense, raccoon incense, and spicy aroma are used.

Examples of synthetic fragrances include linalool, linalyl acetate, geraniol, citronellol, C _{4 to} C ₁₂ various aliphatic aldehydes, phenylethyl alcohol, benzyl acetate, geranyl acetate, geranyl formate, vanillin, nitromusks, Galaxolide, tonalide, pentalide, Santarex, amyl salicylate, amyl acetate, γ-
Undecalactone, ethyl methylphenylglycidate,
Heliotrobin and the like. These fragrances may be used alone or as a mixed fragrance prepared by mixing two or more kinds.

Surfactants are roughly classified into nonionic surfactants, anionic surfactants and cationic surfactants. Nonionic surfactants include polyoxyethylene alkyl ether and polyoxyethylene. Alkyl phenyl ether, polyoxyethylene fatty acid ester, polyoxyethylene hydrogenated castor oil, and the like, and particularly, the average addition mole number of ethylene oxide is 1 to 30, preferably 5 to 2.
The polyoxyethylene-based nonionic surfactant of 5 can be preferably used. Also, alkylamine oxide and the like can be used. Examples of the anionic surfactant include alkyl sulfate, alkylbenzene sulfonate, polyoxyethylene alkyl ether sulfate, polyoxyethylene alkyl phenyl ether sulfate, polyoxyethylene alkyl phenyl ether sulfonate, and the like. Oxyethylene alkylphenyl ether sulfate and polyoxyethylene alkylphenyl ether sulfonate are preferable. Further, examples of the cationic surfactant include alkyl trimethyl ammonium salt and polyoxyethylene alkyl trimethyl ammonium salt. These surfactants may be used alone or in combination of two or more kinds.

Finally, as the solvent, ethanol, propanol, ethylene glycol, propylene glycol, butylene glycol, hexylene glycol, dipropylene glycol, ethylene glycol monoethyl ether, propylene glycol monomethyl ether, propylene glycol monoethyl ether, dipropylene. Examples include glycol monomethyl ether, dipropylene glycol monoethyl ether, 3-methoxy-3-methylbutanol, isoparaffin, dipentene and the like.

[0029]

EXAMPLE Next, the liquid fragrance A to be filled in the soft package 10 of the liquid fragrance sustained-release apparatus 1 of the present embodiment was blended and prepared in various composition ratios as described below. (Example 1) Perfume 2% by weight Polyoxyethylene alkyl ether 2 Polyoxyethylene hydrogenated castor oil 1 Ethanol 5 BHT trace Yellow No. 1 trace water balance Total 100

[0030] (Example 2) Perfume 1 wt% alkylphenol ethoxylate 1.5 Sodium alkyl benzene sulfonate 0.5 Ethanol 3 dihydroxybenzophenone trace Green No. 201 trace water Balance Total 100.0

[0031] (Example 3) Perfume 10 wt% ethanol 20 3-methoxy 3-methyl-butanol 40 BHT trace Green No. 201 trace water balance Total 100

(Example 4) Fragrance 6% by weight Propylene glycol 10 Isoparaffin 40 BHT Trace amount Red No. 106 Trace amount 3-methoxy-3-methylbutanol Total residual amount 100

The liquid fragrances obtained in Examples 1 to 4 are applied to the soft package 10 applied to the liquid fragrance sustained release device 1 which is an embodiment of the volatile drug sustained release device according to the present invention without any gap. After the filling, the soft package 10 was housed in the container 2 and the change over time was observed. It was confirmed that the soft package 10 decreased by a certain amount every predetermined time without being affected by the temperature change around the container 2. Was done.

[0034]

As described above, according to the present invention, in the volatile drug sustained-release device, it is possible to reliably prevent the excessive drug from being discharged to the volatile substance due to the temperature change.

[Brief description of drawings]

FIG. 1 is a perspective view of a liquid fragrance sustained-release device according to a first embodiment.

FIG. 2 is a vertical cross-sectional view of the liquid fragrance sustained releaser according to the first embodiment.

FIG. 3 is a perspective view of the flexible packaging body of FIG.

[Explanation of symbols]

 1 Liquid fragrance sustained release device (an example of a volatile drug sustained release device) 2 Container 3 volatile paper (equivalent to volatile substance) 4 High density impregnated body 9 Discharge part 10 Soft packaging A Liquid fragrance agent

Claims (2)

[Claims] 1. A soft packaging body which is filled with a liquid medicine and has a flexible discharge portion facing downward, a container for accommodating the soft packaging body inside, and a container disposed below the discharge portion. In the volatile drug sustained-release device provided with a volatile material and a liquid-absorbent supplier that supplies the drug in the soft packaging body to the volatile material, the supplier has the above-mentioned properties without air displacement. A volatile drug releaser for supplying a drug in a soft package to the volatile substance. 2. The feeder has a density of 0.6 g / cm ^3.
The volatile drug releaser according to claim 1, which is a high-density impregnated body as described above.