JPH09201396A - Drug dissolving kit and drug dissolving and injection system - Google Patents
Drug dissolving kit and drug dissolving and injection systemInfo
- Publication number
- JPH09201396A JPH09201396A JP8032774A JP3277496A JPH09201396A JP H09201396 A JPH09201396 A JP H09201396A JP 8032774 A JP8032774 A JP 8032774A JP 3277496 A JP3277496 A JP 3277496A JP H09201396 A JPH09201396 A JP H09201396A
- Authority
- JP
- Japan
- Prior art keywords
- drug
- vial
- solution
- port
- liquid medicine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003814 drug Substances 0.000 title claims abstract description 95
- 229940079593 drug Drugs 0.000 title claims abstract description 88
- 238000002347 injection Methods 0.000 title claims description 14
- 239000007924 injection Substances 0.000 title claims description 14
- 238000004090 dissolution Methods 0.000 claims abstract description 28
- 239000000243 solution Substances 0.000 claims description 67
- 239000010410 layer Substances 0.000 claims description 20
- 238000004891 communication Methods 0.000 claims description 16
- 229920003002 synthetic resin Polymers 0.000 claims description 10
- 239000000057 synthetic resin Substances 0.000 claims description 10
- 238000007789 sealing Methods 0.000 claims description 7
- 230000008878 coupling Effects 0.000 claims description 4
- 238000010168 coupling process Methods 0.000 claims description 4
- 238000005859 coupling reaction Methods 0.000 claims description 4
- 239000012790 adhesive layer Substances 0.000 claims description 3
- 239000002356 single layer Substances 0.000 claims description 3
- 239000007788 liquid Substances 0.000 abstract description 13
- 230000003115 biocidal effect Effects 0.000 abstract description 10
- 238000005086 pumping Methods 0.000 abstract description 5
- 238000009434 installation Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 description 7
- 239000003242 anti bacterial agent Substances 0.000 description 6
- 239000000126 substance Substances 0.000 description 6
- 239000000463 material Substances 0.000 description 5
- 238000010586 diagram Methods 0.000 description 4
- 229920001971 elastomer Polymers 0.000 description 4
- 239000005060 rubber Substances 0.000 description 4
- 238000001802 infusion Methods 0.000 description 3
- -1 polypropylene Polymers 0.000 description 3
- 206010011409 Cross infection Diseases 0.000 description 2
- 206010029803 Nosocomial infection Diseases 0.000 description 2
- 239000004743 Polypropylene Substances 0.000 description 2
- 238000000071 blow moulding Methods 0.000 description 2
- 229920003049 isoprene rubber Polymers 0.000 description 2
- 229920001155 polypropylene Polymers 0.000 description 2
- 229920000915 polyvinyl chloride Polymers 0.000 description 2
- 239000004800 polyvinyl chloride Substances 0.000 description 2
- 229920005989 resin Polymers 0.000 description 2
- 239000011347 resin Substances 0.000 description 2
- 210000003462 vein Anatomy 0.000 description 2
- 238000003466 welding Methods 0.000 description 2
- 208000012266 Needlestick injury Diseases 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 230000000274 adsorptive effect Effects 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 230000009089 cytolysis Effects 0.000 description 1
- 229920001038 ethylene copolymer Polymers 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920005672 polyolefin resin Polymers 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 229920003051 synthetic elastomer Polymers 0.000 description 1
- 239000005061 synthetic rubber Substances 0.000 description 1
Landscapes
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
Description
【０００１】[0001]
【発明の属する技術】本発明は、抗生剤等の入っている
バイアル瓶内の薬剤の溶解キット及び溶解・注入システ
ムに関するものである。TECHNICAL FIELD The present invention relates to a dissolution kit and a dissolution / injection system for a drug in a vial containing an antibiotic or the like.
【０００２】[0002]
【従来の技術】従来、バイアル瓶内に納められている抗
生剤等の薬剤の溶解には、次の４通りの方法が取られて
いた。（括弧内は、薬剤溶解後の操作状態を示した） 溶解液の入った薬液容器からシリンジで溶解液を吸入
し、この溶解液をシリンジの針からバイアル瓶のゴム栓
を介して注入し、溶解した抗生剤入りの薬液をシリンジ
で再度溶解液入りの容器にもどす。（シリンジを容器か
ら抜き取る） 溶解液の入った容器とバイアル瓶とを両頭針で連結
し、溶解液入り容器を上にし、バイアル瓶内に溶解液を
注入し溶解後、バイアル瓶を上にして溶解後の薬液を溶
解液入りの容器へもどす。（バイアル瓶と両頭針は、容
器より取り外す） 溶解液入り容器に両頭針が、あらかじめ設けられてい
るキットのタイプであって、と同様に溶解液の入った
容器とバイアル瓶とを両頭針で連結し、溶解液入り容器
を上に、バイアル瓶内に溶解液を注入し溶解後、バイア
ル瓶を上にして溶解後の薬液溶解液入りの容器へもど
す。（バイアル瓶と両頭針は、容器より取り外すタイプ
と取り外さずそのまま使用するタイプとがある） 抗生剤入りのバイアル瓶と溶解液入りの容器とが針を
連通部材としてキット化されているタイプであって、バ
イアル瓶を収納したホルダー内のバイアル瓶を動かして
連結針をバイアル瓶と薬液容器のそれぞれのゴム栓を連
結させ、バイアル瓶内に溶解液を注入後は、と同様に
して、バイアル瓶内の薬液を溶解液入りの薬液容器にも
どす。以上の方法で溶解が完了するが、これらの薬液容
器の薬液を患者に点滴するには、さらに点滴セットを薬
液容器に連結する作業が必要であった。また、、の
タイプはいずれも両頭針を設けて溶解液の入った容器と
バイアル瓶とを連通するのであるが、両頭針をスライド
させる構成を工夫する必要があり、部品点数が増える傾
向があった。2. Description of the Related Art Conventionally, the following four methods have been used to dissolve a drug such as an antibiotic contained in a vial. (The parentheses show the operating state after dissolution of the drug) The solution was inhaled with a syringe from the drug solution container containing the solution, and this solution was injected from the needle of the syringe through the rubber stopper of the vial, The dissolved drug solution containing the antibiotic is returned to the container containing the solution again with a syringe. (Remove the syringe from the container) The container containing the solution and the vial are connected with a double-ended needle, the container containing the solution is on top, the solution is injected into the vial, and the vial is on top. Return the dissolved drug solution to the container containing the solution. (The vial bottle and double-ended needle are removed from the container.) A double-ended needle is a type of kit that is pre-installed in the container containing the dissolving solution. After connection, the solution-containing container is placed on top, and the solution is injected into the vial to dissolve, and then the vial is placed on top and returned to the container containing the dissolved drug solution. (The vial and double-ended needle can be detached from the container or used as they are without being removed.) The vial containing the antibiotic and the container containing the solution are kitted with the needle as the connecting member. Then, move the vial in the holder that stores the vial, connect the connecting needle to the rubber stoppers of the vial and the drug solution container, and after injecting the solution into the vial, do the same as in Return the drug solution inside to the drug solution container containing the solution. Although the dissolution is completed by the above method, in order to drip the drug solution in these drug solution containers to the patient, it is necessary to further connect the drip set to the drug solution container. Also, in both types, a double-ended needle is provided to connect the container containing the solution and the vial, but it is necessary to devise a configuration to slide the double-ended needle, which tends to increase the number of parts. It was
【０００３】[0003]
【発明が解決しようとする課題】バイアル瓶内の抗生剤
等の薬剤を溶解、注入するには、少なくとも２回以上の
針の連結が必要であり、前述のを除いては、一度刺し
た針を抜いた後に薬液容器に点滴セットを連結する作業
が必要である。院内感染等を考慮すると安全性に問題を
有していた。DISCLOSURE OF THE INVENTION In order to dissolve and inject a drug such as an antibiotic in a vial, it is necessary to connect the needles at least twice or more. It is necessary to connect the drip set to the drug solution container after removing. Considering nosocomial infection, etc., there was a problem with safety.
【０００４】抗生剤の入ったバイアル瓶がホルダー内に
納められ、溶解液の入った薬液容器と一体化されたキッ
トとなっているのタイプは、他の方法に比べ、針の差
す回数が少なく、針を抜く作業の無い点においては、有
利に思われるが、その反面、あらかじめ決まった抗生剤
がホルダー内に入れられキットとなっているので、在庫
していたキットが目的とする抗生剤と異なる種類の場合
には、使用できないなど、多種にわたる抗生剤をのタ
イプでそろえるのは、ユーザーの負担が増えるなどの問
題があり、さらに注入に際しては、、、と同様
に、点滴セットを連結する必要があった。また、点滴セ
ットには、通常ポリ塩化ビニル樹脂製のチューブが用い
られており、薬剤によっては、チューブに吸着すること
があり、問題となっていた。現在、、の方法の省力
化が図られ、、のタイプが多く使用されるようにな
ってきているが、前述したとうり、薬剤の溶解後の注入
に際しては、点滴セットを連結する必要があったため、
点滴セットを連結する必要のない製品が望まれていた。
また、、のタイプは、いずれも両頭針を設けて溶解
液の入った容器とバイアル瓶とを連通する方法であるの
で、両頭針をスライドさせる構成を工夫する必要があ
り、部品点数が増える傾向があった。したがって、製造
コストが高くなるため、構成が簡単で、低コスト化が図
れる製品が望まれていた。The type in which a vial containing an antibiotic is housed in a holder and is a kit integrated with a drug solution container containing a dissolving solution requires less number of needle insertions than other methods. , It seems to be advantageous in that there is no work to pull out the needle, but on the other hand, since a predetermined antibiotic is put in the holder to make a kit, the stocked kit is not the target antibiotic. In case of different types, it is not possible to use various types of antibiotics, such as not being able to use, there is a problem that the burden on the user increases, and when injecting, connect the drip set in the same manner as ,. There was a need. In addition, a tube made of polyvinyl chloride resin is usually used for the drip set, and some drugs may be adsorbed to the tube, which is a problem. At present, the method of (1) is labor-saving, and the type of (3) is being widely used. However, as described above, it is necessary to connect an infusion set when injecting a drug after dissolution. Because
A product that does not require the connection of infusion sets has been desired.
In addition, since the type (2) is a method in which a double-ended needle is provided and the container containing the solution is communicated with the vial, it is necessary to devise a configuration to slide the double-ended needle, and the number of parts tends to increase. was there. Therefore, since the manufacturing cost is high, a product having a simple structure and a low cost has been desired.
【０００５】[0005]
【課題を解決するための手段】 ［１］薬液容器２とバイアル瓶ホルダー１１とから構成
され、薬液容器２は、容器本体２ａの上部に連通口３を
形成しかつ下部に薬液の排出口５を形成し、前記連通口
３の上端に結合部材４を形成し、前記排出口５の下端に
栓体９を装着し、バイアル瓶ホルダー１１はホルダー本
体１２の底部内面にバイアル瓶装着口１６と薬液流通口
１３ａを有する穿刺針１３が突設され、穿刺針１３はシ
ース１４を被冠して密封され、ホルダー本体１２の天面
は封止部材１７により密封され、前記ホルダー本体１２
の底部外面と薬液容器２の結合部材４を結合した、薬剤
溶解キット１を提供する。 ［２］［１］記載の薬剤溶解キット１の排出口５の下端
に栓体９を装着する代わりに、排出口２５に連通機構２
７を配置した接続口２６を装着し、これに上部点滴チュ
ーブ２９と下部点滴チューブ３１の間に点滴筒３０を配
置し、下部点滴チューブ３１の末端に静脈針３３を装着
することにより構成される点滴セット部２８を装着した
薬剤溶解・注入システム２１を提供する。 ［３］点滴チューブは、薬剤に対して偽害性のない合成
樹脂よりなる単層チューブまたは、外層に可とう性の合
成樹脂、内層に薬剤に対して偽害性のない合成樹脂、外
層と内層の中間に、少なくとも一層の接着層を形成した
多層チューブである［２］に記載の薬剤溶解・注入シス
テム２１を提供する。[Means for Solving the Problems] [1] A drug solution container 2 and a vial holder 11 are configured. The drug solution container 2 has a communication port 3 formed in an upper part of a container body 2a and a drug solution discharge port 5 in a lower part. And a coupling member 4 is formed on the upper end of the communication port 3, a stopper 9 is attached to the lower end of the discharge port 5, and the vial holder 11 has a vial attachment port 16 on the inner surface of the bottom of the holder body 12. A puncture needle 13 having a medicinal solution flow port 13a is projected, the puncture needle 13 is capped with a sheath 14 and sealed, and the top surface of the holder main body 12 is sealed with a sealing member 17.
Provided is a drug dissolution kit 1 in which the outer surface of the bottom of the above and the connecting member 4 of the drug solution container 2 are combined. [2] Instead of attaching the stopper 9 to the lower end of the discharge port 5 of the drug dissolution kit 1 described in [1], the communication mechanism 2 is connected to the discharge port 25.
7 is mounted, a drip cylinder 30 is arranged between the upper drip tube 29 and the lower drip tube 31, and a venous needle 33 is attached to the end of the lower drip tube 31. A drug dissolution / injection system 21 equipped with a drip setting unit 28 is provided. [3] The drip tube is a single-layer tube made of a synthetic resin that is not falsely harmful to the drug, or a flexible synthetic resin for the outer layer, a synthetic resin that is not falsely harmful to the drug for the inner layer, and an outer layer. There is provided a drug dissolution / injection system 21 according to [2], which is a multilayer tube having at least one adhesive layer formed in the middle of the inner layer.
【０００６】[0006]
【発明の実施の形態】図１は、本発明の薬剤溶解キット
１の概略図である。薬剤溶解キット１は、薬液容器２と
バイアル瓶ホルダー１１とから構成される。薬液容器２
は、ポリプロピレン製で、ブロー成型により容器本体２
ａの上部に連通口３が形成され、下部に薬液の排出口５
が形成されている。連通口３の上端には結合部材として
フランジ４が形成され、排出口５の下端には結合部材と
してフランジ６が形成されている。フランジ６は栓体９
を封入したキャップ７のフランジ８（結合部材）と溶着
され、栓体９の表面はキャップ７の下端にフィルム状封
止部材としてタンパーシールフィルム１０を溶着するこ
とにより密封される。バイアル瓶ホルダー１１はホルダ
ー本体１２の底部内面に筒状のバイアル瓶装着口１６を
突設するとともにこの内側に二つの薬液流通口１３ａを
有する穿刺針１３が突設されている。穿刺針１３にはイ
ソプレンゴム製のシース１４を被冠し、シース１４を穿
刺針１３の基部でシース押さえ１５により固定すること
により、薬液容器２内の溶解液がホルダー本体１２へ移
動するのを阻止することができる。さらにホルダー本体
１２の天面は、封止部材としてタンパーシールフィルム
１７により密封され、ホルダー本体１２の上部側面には
ハンガー１８が設けられている。また前記ホルダー本体
１２の底部外面と薬液容器２のフランジ４は溶着により
結合されている。BEST MODE FOR CARRYING OUT THE INVENTION FIG. 1 is a schematic view of a drug dissolution kit 1 of the present invention. The drug dissolution kit 1 includes a drug solution container 2 and a vial holder 11. Chemical solution container 2
Is made of polypropylene, and the container body 2 is formed by blow molding.
A communication port 3 is formed in the upper part of a, and a chemical solution discharge port 5 is formed in the lower part.
Are formed. A flange 4 is formed as a connecting member at the upper end of the communication port 3, and a flange 6 is formed as a connecting member at the lower end of the discharge port 5. Flange 6 is plug 9
Is welded to the flange 8 (coupling member) of the cap 7, and the surface of the plug 9 is sealed by welding a tamper seal film 10 as a film-shaped sealing member to the lower end of the cap 7. The vial holder 11 has a cylindrical vial mounting port 16 projecting from the inner surface of the bottom of the holder body 12, and a puncture needle 13 having two drug solution circulation ports 13a projecting from the inside. The puncture needle 13 is covered with a sheath 14 made of isoprene rubber, and the sheath 14 is fixed by a sheath retainer 15 at the base of the puncture needle 13 to prevent the solution in the drug solution container 2 from moving to the holder body 12. Can be stopped. Further, the top surface of the holder body 12 is sealed with a tamper seal film 17 as a sealing member, and a hanger 18 is provided on the upper side surface of the holder body 12. The outer surface of the bottom of the holder body 12 and the flange 4 of the chemical solution container 2 are joined by welding.
【０００７】上記の薬剤溶解キット１を用いて、バイア
ル瓶１９中の薬剤を溶解する方法の一例を図２（図１の
薬液溶解キット１の使用時の概略図）に基づいて説明す
る。まずタンパーシールフィルム１７をはぎ取り、開封
した状態のバイアル瓶１９をホルダー本体１２内のバイ
アル瓶装着口１６に押し込み、栓体２０、シース１４を
穿刺針１３で貫通する。その後、薬液容器２を上にして
薬液容器２内の薬液の一部を落差及び、薬液容器２のポ
ンピングを利用してバイアル瓶１９に注入し、バイアル
瓶１９内の薬剤を良く溶解して溶解液とした後、バイア
ル瓶１９を上にしてバイアル瓶１９内の溶解液を落差と
ポンピングにて薬液容器２に移送して、残りの薬液と混
合し、薬剤の溶解を完了する。溶解液を患者に注入する
には、タンパーシールフィルム１０をはぎ、栓体７に点
滴セットの瓶針（図示せず）を穿刺して注入する。An example of a method for dissolving the drug in the vial 19 using the drug dissolving kit 1 will be described with reference to FIG. 2 (schematic diagram when the drug solution dissolving kit 1 of FIG. 1 is used). First, the tamper seal film 17 is peeled off, the opened vial bottle 19 is pushed into the vial bottle mounting port 16 in the holder body 12, and the stopper 20 and the sheath 14 are penetrated by the puncture needle 13. After that, with the drug solution container 2 facing up, a part of the drug solution in the drug solution container 2 is dropped and injected into the vial bottle 19 by utilizing the pumping of the drug solution container 2, and the drug in the vial bottle 19 is well dissolved and dissolved. After being made into a liquid, the solution in the vial 19 is transferred to the drug solution container 2 by dropping and pumping with the vial 19 facing upward and mixed with the remaining drug solution to complete the dissolution of the drug. To inject the solution into the patient, the tamper seal film 10 is peeled off, and the stopper 7 is pierced with a bottle needle (not shown) of the drip set to inject the solution.
【０００８】図３は、本発明の薬剤溶解・注入システム
２１の概略図である。図３の薬剤溶解・注入システム２
１は、図１の薬剤溶解キット１の排出口５の下端に栓体
９を装着する代わりに、排出口２５の下端に連通機構と
して連通ピース２７を配置した接続口２６を装着し、接
続口２６に点滴セット部２８を構成する上部点滴チュー
ブ２９を接続したものである。点滴セット部２８は上部
点滴チューブ２９と下部点滴チューブ３１の間に点滴筒
３０を配置し、下部点滴チューブ３１の間にクランプ３
２を設けかつ末端に静脈針３３を装着することにより構
成されている。FIG. 3 is a schematic diagram of the drug dissolution / injection system 21 of the present invention. Drug dissolution / injection system 2 in FIG.
1, instead of mounting the plug 9 on the lower end of the discharge port 5 of the drug dissolution kit 1 of FIG. 1, a connection port 26 having a communication piece 27 as a communication mechanism is mounted on the lower end of the discharge port 25. An upper drip tube 29, which constitutes a drip setting unit 28, is connected to the device 26. In the drip setting unit 28, a drip tube 30 is arranged between an upper drip tube 29 and a lower drip tube 31, and a clamp 3 is placed between the lower drip tube 31.
2 is provided and a venous needle 33 is attached to the distal end.
【０００９】上記の薬剤溶解・注入システム２１を用い
て、バイアル瓶４３中の薬剤を溶解、注入するには、ま
ずタンパーシールフィルム４１をはぎ取り、開封した状
態のバイアル瓶４３をバイアル瓶ホルダー３４内のバイ
アル瓶装着口４０に押し込み、ゴム栓４４、シース３７
を穿刺針３６で貫通する。その後、薬液容器２２を上に
して薬液容器２２内の薬液の一部を落差及び、薬液容器
２２のポンピングを利用してバイアル瓶４３に注入し、
バイアル瓶４３内の薬剤を良く溶解して溶解液とした
後、バイアル瓶４３を上にしてバイアル瓶４３内の溶解
液を落差とポンピングにて薬液容器２２に移送して、残
りの薬液と混合し、薬剤の溶解を完了後、次の注入の操
作に入る。In order to dissolve and inject the drug in the vial bottle 43 using the above drug dissolving / injecting system 21, the tamper seal film 41 is first peeled off, and the opened vial bottle 43 is placed in the vial holder 34. The rubber stopper 44 and the sheath 37.
With a puncture needle 36. Thereafter, with the drug solution container 22 facing upward, a part of the drug solution in the drug solution container 22 is dropped, and pumping of the drug solution container 22 is used to inject it into the vial bottle 43,
After the drug in the vial bottle 43 is well dissolved to form a solution, the solution in the vial bottle 43 is transferred to the drug solution container 22 by dropping and pumping with the vial bottle 43 facing up and mixed with the remaining drug solution. Then, after the dissolution of the drug is completed, the next injection operation is started.
【００１０】クランプ３２を閉めた後、接続口２６内の
連通ピース２７を破断し、点滴筒３０をポンピングし、
適量の溶解液を点滴筒３０内に導入した後、クランプ３
２を調整、解放し、下部点滴チューブ３１、静脈針３３
の順に溶解液を通して、患者の静脈に静脈針３３を穿刺
する。なお、図１、図３に示した薬液容器２（２２）
は、ポリプロピレンを構成材料として使用しブロー成型
により連通口３（２３）と排出口５（２５）を一体化す
る旨を述べたが、他の材料を用いることや、２枚のシー
トやインフレーションチューブの間に連通口３（２３）
と排出口５（２５）をはさんで溶着して作製しても良
い。また、シース１４、３７には、イソプレンゴムを使
用する旨を述べたが、溶解液の密封性、穿刺針との連通
性を有する他の合成ゴムや、合成樹脂を用いても良い。After closing the clamp 32, the communication piece 27 in the connection port 26 is broken, and the drip tube 30 is pumped.
After introducing an appropriate amount of solution into the drip tube 30, the clamp 3
2. Adjust and release 2, lower drip tube 31, venous needle 33
The venous needle 33 is punctured into the vein of the patient by passing the lysis solution in the order of. The chemical liquid container 2 (22) shown in FIGS. 1 and 3
Describes that polypropylene is used as a constituent material and the communication port 3 (23) and the discharge port 5 (25) are integrated by blow molding, but other materials may be used, or two sheets or an inflation tube may be used. Communication port 3 (23) between
The discharge port 5 (25) may be sandwiched and welded. Further, although it has been described that isoprene rubber is used for the sheaths 14 and 37, other synthetic rubber or synthetic resin having a sealing property of the solution and a communication with the puncture needle may be used.
【００１１】図４は、図３の下部点滴チューブ３１の断
面図である。図４に示した下部点滴チューブ３１は、押
出成形により形成され、外層４５を可とう性合成樹脂
（例えばポリ塩化ビニル樹脂）、内層４７を薬剤に対し
て偽害性のない（例えば薬剤非吸着性）合成樹脂（例え
ばポリエチレン等のオレフィン系合成樹脂）、中間層４
６に外層４５と内層４７の接着層として、例えばエチレ
ン系共重合体ベースの接着性ポリオレフィン樹脂を使用
することにより構成される。（上部点滴チューブ２９も
下部点滴チューブ３１と同様に構成される。）なお、前
記点滴チューブ２９、３１は前記以外の材料の組み合わ
せや、三層以上の多層チューブで構成しても良いし、あ
るいは薬剤に対して偽害性のない単層チューブで構成し
ても良い。FIG. 4 is a sectional view of the lower drip tube 31 of FIG. The lower drip tube 31 shown in FIG. 4 is formed by extrusion molding, the outer layer 45 is a flexible synthetic resin (for example, polyvinyl chloride resin), and the inner layer 47 is not falsely harmful to the drug (for example, drug non-adsorption). Properties) synthetic resin (for example, olefinic synthetic resin such as polyethylene), intermediate layer 4
6, the adhesive layer of the outer layer 45 and the inner layer 47 is formed by using, for example, an adhesive polyolefin resin based on an ethylene copolymer. (The upper drip tube 29 is also constructed in the same manner as the lower drip tube 31.) The drip tubes 29 and 31 may be made of a combination of materials other than the above, or may be composed of a multi-layer tube having three or more layers, or It may be composed of a single-layer tube that is not falsely harmful to the drug.
【００１２】[0012]
【発明の効果】本発明に用いるバイアル瓶ホルダーは、
連結針が一体成形されているので、部品点数が少なく、
コストダウンを図ることができる。また、本発明の薬剤
溶解・注入システムは、バイアル瓶内の抗生剤の溶解か
ら患者への注入までの一連の作業を、針を刺す回数が少
なく、院内感染等の問題もなく安全かつ簡便に行える。
また、点滴セット部に用いられるチューブの内層は、薬
剤に対して偽害性のない材料（薬剤非吸着性材料）を用
いているので薬剤注入時、チューブに薬剤が吸着される
ことがない。さらに、本発明の薬剤溶解キット、薬剤溶
解・注入システムは、あらかじめ決まった薬剤と組み合
わされていず、薬剤の種類に関わらず使用が可能である
ので、在庫の管理やスペースの点で有利である。The vial holder used in the present invention is
Since the connecting needle is integrally molded, the number of parts is small,
Cost can be reduced. Further, the drug dissolution / injection system of the present invention is a safe and simple procedure for a series of operations from dissolution of an antibiotic in a vial to injection into a patient, with a small number of needle sticks and no problem of nosocomial infection. You can do it.
Further, since the inner layer of the tube used for the drip setting section is made of a material that is not falsely harmful to the drug (drug non-adsorptive material), the drug is not adsorbed to the tube during drug injection. Furthermore, the drug dissolution kit and drug dissolution / infusion system of the present invention are not combined with a predetermined drug and can be used regardless of the type of drug, which is advantageous in terms of inventory management and space. .
【図１】本発明の薬剤溶解キットの概略図FIG. 1 is a schematic view of a drug dissolution kit of the present invention.
【図２】図１の使用状態図FIG. 2 is a use state diagram of FIG.
【図３】本発明の薬剤溶解・注入システムの概略図FIG. 3 is a schematic diagram of a drug dissolution / injection system of the present invention.
【図４】図３の点滴チューブＡ−Ａの断面図4 is a cross-sectional view of the drip tube AA of FIG.
１ 薬剤溶解キット ２、２２ 薬液容器 ２ａ、２２ａ 容器本体 ３、２３ 連通口 ４、６、８、２４ 結合部材（フランジ） ５、２５ 排出口 ７ キャップ ９、２０、４４ 栓体（ゴム栓） １０ 封止部材（タンパーシールフィル
ム） １１、３４ バイアル瓶ホルダー １２、３５ ホルダー本体 １３、３６ 穿刺針 １３ａ、３６ａ 薬液流通口 １４、３７ シース １５、３８ シース押さえ １６、４０ バイアル装着口 １７、４１ 封止部材（タンパーシールフィル
ム） １８、４２ ハンガー １９、４３ バイアル瓶 ２１ 薬剤溶解・注入システム ２６ 接続口 ２７ 連通機構（連通ピース） ２８ 点滴セット部 ２９ 上部点滴チューブ ３０ 点滴筒 ３１ 下部点滴チューブ ３２ クランプ ３３ 静脈針 ４５ 外層 ４６ 中間層 ４７ 内層1 Drug Dissolution Kit 2, 22 Chemical Liquid Containers 2a, 22a Container Main Body 3, 23 Communication Ports 4, 6, 8, 24 Coupling Member (Flange) 5, 25 Discharge Port 7 Cap 9, 20, 44 Plug (Rubber Plug) 10 Sealing member (tamper seal film) 11, 34 Vial bottle holder 12, 35 Holder body 13, 36 Puncturing needle 13a, 36a Chemical liquid flow port 14, 37 Sheath 15, 38 Sheath presser 16, 40 Vial mounting port 17, 41 Sealing Member (tamper seal film) 18, 42 Hanger 19, 43 Vial bottle 21 Drug dissolution / injection system 26 Connection port 27 Communication mechanism (communication piece) 28 Drip set part 29 Upper drip tube 30 Drip tube 31 Lower drip tube 32 Clamp 33 Vein Needle 45 Outer layer 46 Middle layer 47 Inner layer
Claims (3)
ら構成され、 薬液容器２は、容器本体２ａの上部に連通口３を形成し
かつ下部に薬液の排出口５を形成し、前記連通口３の上
端に結合部材４を形成し、前記排出口５の下端に栓体９
を装着し、 バイアル瓶ホルダー１１はホルダー本体１２の底部内面
にバイアル瓶装着口１６と薬液流通口１３ａを有する穿
刺針１３が突設され、穿刺針１３はシース１４を被冠し
て密封され、ホルダー本体１２の天面は封止部材１７に
より密封され、 前記ホルダー本体１２の底部外面と薬液容器２の結合部
材４を結合した、ことを特徴とする薬剤溶解キット１。1. A drug solution container 2 and a vial holder 11. The drug solution container 2 has a communication port 3 formed in an upper part of a container body 2a and a drug solution discharge port 5 in a lower part thereof. A coupling member 4 is formed at the upper end of the discharge port 3, and a plug 9 is formed at the lower end of the discharge port 5.
The vial holder 11 is equipped with a vial mounting port 16 and a puncture needle 13 having a drug solution flow port 13a on the inner surface of the bottom of the holder body 12, and the puncture needle 13 is covered with a sheath 14 and sealed. The top surface of the holder body 12 is sealed by a sealing member 17, and the outer surface of the bottom of the holder body 12 and the joining member 4 of the drug solution container 2 are joined together.
５の下端に栓体９を装着する代わりに、排出口２５に連
通機構２７を配置した接続口２６を装着し、これに上部
点滴チューブ２９と下部点滴チューブ３１の間に点滴筒
３０を配置し、下部点滴チューブ３１の末端に静脈針３
３を装着することにより構成される点滴セット部２８を
装着したことを特徴とする薬剤溶解・注入システム２
１。2. Instead of attaching the plug 9 to the lower end of the discharge port 5 of the drug dissolution kit 1 according to claim 1, a connection port 26 having a communication mechanism 27 is attached to the discharge port 25, and the connection port 26 is attached to the upper part thereof. The drip tube 30 is arranged between the drip tube 29 and the lower drip tube 31, and the venous needle 3 is attached to the end of the lower drip tube 31.
3. A drug dissolution / injection system 2 characterized in that a drip set part 28 constituted by mounting 3 is mounted.
One.
い合成樹脂よりなる単層チューブまたは、 外層に可とう性の合成樹脂、内層に薬剤に対して偽害性
のない合成樹脂、外層と内層の中間に、少なくとも一層
の接着層を形成した多層チューブであることを特徴とす
る請求項２に記載の薬剤溶解・注入システム２１。3. A drip tube is a single-layer tube made of a synthetic resin that is not falsely harmful to a drug, or a flexible synthetic resin is an outer layer, and a synthetic resin that is not falsely harmful to a drug is an inner layer, The drug dissolution / injection system 21 according to claim 2, which is a multi-layer tube in which at least one adhesive layer is formed between the outer layer and the inner layer.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP08032774A JP3142770B2 (en) | 1996-01-26 | 1996-01-26 | Drug dissolution kit and drug dissolution / injection system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP08032774A JP3142770B2 (en) | 1996-01-26 | 1996-01-26 | Drug dissolution kit and drug dissolution / injection system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH09201396A true JPH09201396A (en) | 1997-08-05 |
| JP3142770B2 JP3142770B2 (en) | 2001-03-07 |
Family
ID=12368195
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP08032774A Expired - Fee Related JP3142770B2 (en) | 1996-01-26 | 1996-01-26 | Drug dissolution kit and drug dissolution / injection system |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP3142770B2 (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014046950A1 (en) * | 2012-09-24 | 2014-03-27 | Enable Injections, Llc | Medication vial and injector assemblies and methods of use |
| US20150005734A1 (en) * | 2011-12-29 | 2015-01-01 | Otsuka Pharmaceutical Factory, Inc. | Exposure prevention cover, exposure prevention cover module provided with same, drug solution supply system, and drug solution supply method |
| JPWO2013172449A1 (en) * | 2012-05-17 | 2016-01-12 | 味の素製薬株式会社 | Connecting member with needle, drug dissolution kit |
| US9925333B2 (en) | 2013-06-18 | 2018-03-27 | Enable Injections, Inc. | Vial transfer and injection apparatus and method |
-
1996
- 1996-01-26 JP JP08032774A patent/JP3142770B2/en not_active Expired - Fee Related
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20150005734A1 (en) * | 2011-12-29 | 2015-01-01 | Otsuka Pharmaceutical Factory, Inc. | Exposure prevention cover, exposure prevention cover module provided with same, drug solution supply system, and drug solution supply method |
| JPWO2013172449A1 (en) * | 2012-05-17 | 2016-01-12 | 味の素製薬株式会社 | Connecting member with needle, drug dissolution kit |
| WO2014046950A1 (en) * | 2012-09-24 | 2014-03-27 | Enable Injections, Llc | Medication vial and injector assemblies and methods of use |
| US10729842B2 (en) | 2012-09-24 | 2020-08-04 | Enable Injections, Inc. | Medical vial and injector assemblies and methods of use |
| US9925333B2 (en) | 2013-06-18 | 2018-03-27 | Enable Injections, Inc. | Vial transfer and injection apparatus and method |
| US11040138B2 (en) | 2013-06-18 | 2021-06-22 | Enable Injections, Inc. | Vial transfer and injection apparatus and method |
Also Published As
| Publication number | Publication date |
|---|---|
| JP3142770B2 (en) | 2001-03-07 |
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