JPH0916681A - Medicine discriminating device - Google Patents

Abstract

PURPOSE: To automatically discriminate each medicine by preparing a data base for registering the appearance condition of each brand, inquiring a preparing medicine to be inspected by a computer by using its appearance condition as a retrieving item and specifying the brand name of the medicine by the matching of retrieval. CONSTITUTION: One component of propionic acid group antipyretic/analgesics, e.g., is selected from an indication list issued from Japanese Pharmacist Association, the constitutional formula part of the medicine is converted into image data, the other noun part is convered into a free keyword to electronically express the medicine data, and while referring to formulation identification codes described at the end of Japanese pharmaceutical list, electronic identification recording data such as a mark and a symbol in each brand are prepared. Physical measuring data consisting of the weight, maximum diameter, color, capsule size of each medicine brand are electronically stored and these data are identified by a bar code in each product. When a formulation characteristic is used as a retrieving item and inputted to a computer 1 to 4 by manual operation, a completely coincident product name is retrieved from an existing data base, the product name can be specified.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an automated drug discrimination apparatus utilizing the inquiry and retrieval function of a computer.

[0002]

2. Description of the Related Art The development of computers, electronic devices, and software has been remarkable recently. With the construction of information highways in the United States, the spread of communication and cable television in ordinary households, and the change in the industrial structure that has become multi-media. Steadily progressing. Although it is a small scale in Japan, although digitization is in progress in fields such as retail inventory management and patent procedures, progress is made further due to the fact that standards are not uniform, strict regulations and communication charges are expensive. The reality is not to do it. Especially in the medical industry, trial development of electronic prescriptions and comprehensive hospital information systems has been attempted, but due to problems such as the claim for medical health points, the manual work is still in progress [Toshiba Hospital Information system, ARI
S side effect database (Odashima), electronic medical record (Japan Healthcare Information Systems Industry Association, etc.)].

[0003]

[Problems to be solved by the invention] Recently, a visiting medical care system has also been established in Japan, and it is not so expert when a visitor receives a drug inquiry from a patient or when examining the contents of a dispensed drug in a medicine bag. As long as it is not possible to make a visual distinction, it often takes a very long time to make a distinction because it is necessary to confirm it with the prescriber. For this reason, there is a problem that the patient's simple questions cannot be answered immediately.

Pharmaceuticals in Japan (hereinafter referred to as pharmaceuticals) are roughly classified into those for physicians and those for general use. Over-the-counter drugs are directly purchased by the user after receiving explanations from the pharmacy, and the efficacy statement and ingredient names are attached, so there are few problems, but for medical doctors, many new drugs with unknown side effects, Patients who actually take efficacy indications do not have the opportunity to see it, and it is basically believed that they believe in the prescription of a specialist. Therefore, problems such as patient anxiety and inability to accurately grasp medication in medical accidents have been pointed out (thinking that the user does not have the right to know the drug name in terms of mental effects).

[0005] The medicine for medical practitioners has an advantage that the actual payment amount of the patient is small because it is an insurance burden (often, many kinds of medicines are dispensed without paying attention to the price), however, the patient does not operate in parallel with a plurality of medical institutions. It has been pointed out that there are problems in going to the hospital or leaving psychiatric drugs or anesthetics with unknown ingredients and names, and leaving them to families and acquaintances because they think they are all medicines.

In the worst case, when a manufacturer or a medical institution mistakenly prescribes a drug (since the production line of the anticancer drug and the production line of the gastrointestinal drug are the same, the raw material of the anticancer drug is mistakenly manufactured as the gastrointestinal drug and is packaged. Etc.), even if it is a licensed manufacturer or an expert, the enhancement of multiple check functions is called for to prevent human error.

{Patients who have been practicing medical care at a plurality of medical institutions and died due to repeated administration of medicines (increased dose), patients died due to swallowing prescription (drinking poisoning), virus mixture, new drug It took time for the side effect report to reach the end due to administrative regulations and the number of deaths and the number of infections increased, etc. There are few cases of being caught, but it is slow after the damage occurs)}

[0008] Therefore, it is necessary to establish a division of labor system (function to separate medication and medication for the purpose of avoiding medication mistakes and duplicate prescriptions and double-check at independent independent institutions), discovery, disclosure system (medical record Centralized storage evidence preservation function by a third-party organization, obligation to disclose), Informed Consensus (Except for psychotherapy, when the prescription is received, the name of the drug taken by the patient himself / herself can be confirmed, and if desired, explanation of the medication depending on the prescription content. However, there is a need for institutional reforms that are as easy as the end-of-the-Western countries, such as the introduction of new drug inspection systems. (It is said that the number of them is 10,000, and it is one of the world's leading large-volume consumer markets for pharmaceuticals.) Due to its vested interests, complexity and complexity, it is difficult to make any progress. It is.

Several hundred kinds of chemicals are released every year, and the number of them is increasing more and more. Even if the drugs have the same ingredients, the appearance and shape are different depending on the manufacturer. For example, "Tablet identification dictionary (hospital pharmacy department)""Nippon Pharmaceutical Collection (medical information center)" for specialists Books such as the book that tells me the medicine I got from a doctor and the book that tells me the medicine sold at the pharmacy (Kodansha) are on sale, but the search items consist of visual range (heat seals and symbols There is a defect that it takes time for discrimination even for a proper expert.

In particular, a packet, a tablet whose seal has been peeled off,
For preparations in which capsules or powders are combined (after being packaged for each dose, etc.), it is impossible to make a distinction without asking the testing institute for confirmation tests of physicochemical properties and waiting for a few days. It is a situation.

[0011]

[Means and actions for solving the problems]

(Summary of the Invention) The present invention proposes an automated drug identification method and apparatus for solving the above problems.

[0012] The first method is a method in which a booklet body is used for a manual investigation, but is simply diverted to a computer inquiry retrieval method. This method creates a database in which the appearance conditions (mark, code, number) for each brand are registered in advance, and then a matching search is performed in the computer using the appearance conditions as the search item from the dispensing drug to be investigated, This is a method of specifying the product name. This method is limited to preparations in which appearance identification items such as marks, codes, numbers, etc. that are engraved with solid agents are clearly described, and even in the case of granules and powders, the brand name and ingredients are stated in the packaging part. Can be used.

The second method is used for investigating a single drug without an external display, and is a physical identification item (weight,
Only the color tone, optics, magnetism, electrical conductivity, sound waves, light rays such as X-rays, etc.) are used to electronically record the detection data of the measuring device in the computer, and the individual data for each preparation This is a method of specifying a brand name by performing comparison with data for each product registered in advance as a search inquiry item (execution of inquiry search).

The third method is used for investigating mixed preparations, and is generally a physical identification item (volume, weight, viscosity) obtained from a mixed formulation of liquid medicines and powders that are often used. , Color mixing, optics, magnetism, conductivity, sound waves, X-rays, etc.) are registered in advance, and multiple product names can be obtained by comparing and inquiring the physical identification items of the preparations to be tested. This is a method of predicting and verifying the content if desired.

As the fourth method, the mixed preparation of the third method is used in the form of tablets, capsules, pills, granules,
After sieving into fine powder parts, the brand name is specified by the first or second method.

In actual use, the first method is usually the simplest method for patients, and most drugs can be distinguished by the search items such as symbols and numbers. However, solid preparations for internal use are mixed in the preparation. In the case of tablets, capsules, granules, pills,
After sieving into powder, a method of individually assaying the powder by the second method is preferable. Further, in the case of powder search, a plurality of powders may be mixed in some cases, and the third method is preferable.

The first method is sufficient if it has a drug external appearance input device (manual input from a keyboard is possible), a computer and a standard drug database (CD ROM version, etc.). In the fourth method, it is desirable to construct a database so that the chemical properties of the drug can be assayed and inquired at the same time, so that it can be sufficiently provided to specialists and medical institutions by the online method (manufacturing approval). It is desired to establish infrastructure such as digitization of product characteristic data, clinical data, pharmacological data, etc. at the time of approval, and accumulation as a database).

As a method for reading and recording the appearance display characteristics and measured value characteristics of a drug, a measuring instrument is joined and the characteristics such as the shape are directly measured, weighed and recorded (primary reading method), and a micro bar code and the like. An electronic reading method (secondary reading method) is devised in which characteristic information is recorded using computer codes.

The former is more realistic although it has a problem that a read error is likely to occur when the quality is poor. In the latter case, recording elements such as semiconductor chips and computer codes such as micro bar codes are recorded (printed) on a box, label, heat seal or the preparation itself, and the product is specified and the characteristic data of the standard product is recorded. It is a method of inquiring. Regarding the method of embedding, engraving, and printing on the surface of capsules and tablets, it is necessary to standardize the material, recording method, etc. in the future, including safety issues when recording on clothes, and it is currently a test area. However, future development is expected in that the information can be read accurately.

Hereinafter, the present invention will be described in more detail with reference to prototype test examples. In the embodiment of the present invention, an advanced inquiry search function can be added by increasing the amount of data and the number of physical measurement items. Therefore, the present invention is not limited to the examples.

[0021]

【Example】

Prototype example 1) Creation of drug database We selected one component of propionic acid-based antipyretic analgesic (alclofenac) from the booklet published by the Japanese Society of Pharmacists, the structural formula part as image data, and other noun parts as free keywords. As a result, the original product data was digitized and the identification record data such as marks and symbols for each brand were digitized with reference to the formulation identification code at the end of the Japan Pharmaceutical Sciences Collection (Japan Pharmaceutical Information Center).

The physical measurement data is stored electronically by limiting the product weight, maximum diameter, color tone, and number of capsules for each drug brand (electronic data table 1, index search item table 2,
Image input table 3), each product is identified by a highly popular barcode.

[0023]

[Table 1] Dosage form tablets 250mg Drug price 14.00 Product name Almethosin tablets Allopidine tablets Neurofenac tablets Brecuron tablets Manufacture Tatsumi Chugai Toyo Shinsei Issei Taiyo Yakuhin Co., Ltd. Athens Mech Apyrojust Alphenadine Capsule Manufacturing Tsuruhara Yoshindo Kenseido Kenyu Product Name Allopidine Capsule Miasulin Capsule Manufacturing Chugai Daito Trading Towa

[0024]

[Table 2] Product name, manufacturer / manufacturer, manufacturer / manufacturer mark / symbol (heat seal, engraving, printing) Dosage form [capsule: soft capsule, hard capsule, color tone (body, cap), standard (weight), medicinal effect] [Tablet: film coat, sugar coating, naked (single layer, nucleated, multilayer), color tone, standard (weight), medicinal effect],
Standard product classification (medicinal effect classification), drug price, daily dose, compound name, general name, chemical abstract registry number, Merck index number, summary sentence created from the notation free keyword, weight, longest diameter, hardness

[0025]

[Table 3] Chemical structure formula, booklet, product appearance photograph (heat seal, formulation part), pamphlet promotional material provided by the manufacturer,
Product newspaper articles, side effect materials

2) Structure of test equipment For the trial production test, the measurement data was manually input into the computer and searched.

3) Results and Consideration This is a method for identifying a product name by searching for an exact match from an existing database by manually inputting it into a computer, using a formulation property as a search item. By connecting to, automatic search becomes possible. In particular, a small barcode can be printed by printing a small barcode on the surface of the capsule or tablet in advance, enlarging it once on the screen and then reading it by the device or by reading it directly.

[0028]

[Effects of the Invention] An apparatus method for professionals for assaying drugs without the need to hold huge product data by a method of receiving the latest product outline, clinical data, side effect data, and product characteristic data by wire or radio waves, and one CD ROM (EN) Provided is an apparatus method for easily investigating and discriminating a drug by operating product data having a certain amount of information at home. It has a wide range of applications, from hobby surveys of medications to drug appraisals by medical assistants and experts.

[Brief description of the drawings]

FIG. 1 shows a drug assay step diagram according to the present invention.

FIG. 2 shows a complete view of a product characteristic reading device according to the present invention (bar code reading device portion-mouse-like peripheral device for reading a bar code printed on a medicine or medicine bag and inputting it to a computer).

FIG. 3 shows an example of a device characteristic (solid dosage form) reading device portion of the present invention (a mouse-like peripheral device in which a tablet and a capsule are put in a predetermined receiving port, and the size and hardness are read by a movable major to a computer. )

FIG. 4 shows an example of a device characteristic (liquid agent) reading device part of the present invention (powder, liquid agent, ointment, etc.) is put in a capsule-like device in advance, and is put into the receiving port of the device to give a vibration, and then is optically Mouse-like peripheral device that reads characteristics and inputs them to a computer)

FIG. 5 shows a complete view of a simplified assay device (an example of a simplified device in which the formulation characteristic reading device described in FIGS. 2 to 4 and a computer, a keyboard, and a screen are combined)

FIG. 6 shows a basic block diagram of the drug investigation device of the present invention.

[Explanation of symbols]

1-Central Processing Unit, 2-RAM, 3-ROM, 4-Interface 5-Mouse, 6-Display Keyboard, 7-Disc, 8-Preparation Test Equipment, 9-Adjustable Capsule Receiving Port (Measurement Sensor) 10-caliber type tablet receiving port (size and hardness measuring sensor) 11-optical measuring sensor, 12-liquid agent insertion container receiving port 13-communication electric cord, 14-liquid agent inserting container 15, operation keyboard 16-liquid crystal display screen 17 ~ Test product extract button

Claims (2)

[Claims] Claims 1) Appearance display characteristics such as color tone, size, shape, symbol, mark, code, etc., hardness, weight, specific gravity or magnetism / conductivity / sound wave / light ray such as visible / infrared / ultraviolet. A means for electronically reading and recording the measured value characteristics by X-rays, transmitted rays, and laser light on the display screen, and 2) manually selecting the displayed and recorded appearance display characteristics or measured value characteristics on the display screen. Alternatively, means for automatically inputting, and 3) a measurement value characteristic designated by the operation of the input means does not serve as an inquiry search item, and is searched from a pre-registered drug information database to completely match or approximate the product name (product Name, compound name, etc.) on the screen in order of probability, 4) means to select the product name displayed in order of probability on the display screen and enter it manually or automatically, 5) a statement of the applicable drug (Indications, effects, precautions for use, etc.)
Also, a drug discrimination device comprising means for displaying academic information required for medication on a screen, and controlling the above means by using a sensor, a computer with a built-in program, and a drug database on the screen. 2. The formulation characteristic sensor and the computer with built-in program are in a joined state, and the formulation characteristic sensor is a solid agent (tablet / pill, capsule, powder / granule), liquid agent (liquid / emulsion / ointment). ) Or the content sensor function from the outside of the medicine bag, the computer has the inquiry and search function or the function of connecting to the host computer as a terminal, and the function statement (effects, effects, precautions for use, etc.) of the drug and medication. A drug identification device characterized by being configured so that required academic information can be searched and retrieved at the same time.