JPH09124423A - Production of environmental bactericide composition - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain the subject composition having excellent durability of bactericidal action and useful as a slime-controlling agent for kitchen and toilet by forming and curing a mixture of an iodophor and α-gypsum hemihydrate. SOLUTION: An iodophor is mixed with α-gypsum hemihydrate at a weight ratio of 2:98 to 50:50 in teams of solid in the presence of water and the mixture is kneaded, molded and cured e.g. by extrusion molding. The iodophor is preferably povidone iodine having an effective iodine content of 5-15%. The strength of the molded solid article and the sustained releasability of iodine can be improved by adding an organic or inorganic binder or excipient (e.g. dextrin) in molding. The molded and cured product can be impregnated with a solution of iodine and a water-soluble or alcohol-soluble iodide to further improve the antibacterial action. The agent exhibits bactericidal action on microorganisms such as Escherichia coli, Pseudomonas aeruginosa, dysentery bacillus, Salmonella, Klebsiella, Campylobacter and Staphylococcus aureus.

Description

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The present invention relates to a method for producing an environmental disinfectant (sanitizer) composition containing iodine, and more particularly to an environmental disinfectant composition having excellent sustainability of disinfection. . The invention further relates to anti-smudge agents for kitchens and toiletries.

[0002]

2. Description of the Related Art It is necessary to control harmful microorganisms in an environment where foods are handled or in an office, a home or the like. Although steam, hot water, and ultraviolet irradiation are important means for sterilizing the environment, environmental sterilizers (sanitizers, Sanitizers) can be used more easily.
There is use of

As general environmental bactericides, various halogen-based, surfactant-based, aldehyde-based, biguanide-based, phenol-based, oxygen-based, etc. are known.
Iodophor, for example, povidone iodine (a complex of polyvinylpyrrolidone and iodine) is also drawing attention.

US Pat. No. 5,043,090 discloses that
Compounded with dihydrate gypsum, anhydrous gypsum, vapor-phase silica, iodine, povidone, dye and polyethylene oxide polymer to produce a solid cake containing iodine and automatically releasing the cleaning agent to the toilet. It is described that the obtained product is tablet-molded.

[0005]

Iodophor such as povidone iodine is a complex that has a bactericidal action but does not have the unpleasant odor peculiar to iodine, and has the action of gradually releasing iodine in water. The holes themselves are easily soluble in water and have the drawback that they easily elute upon contact with water.

As seen in the above-mentioned conventional example, a solid cake in which iodine is held by an absorbent or adsorbent such as gypsum dihydrate has a certain amount of iodine holes because iodine is held in the cake. Although it has a sustained release property, it is originally a powder that absorbs liquid iodine holes and is tablet-molded, so the solid cake may disintegrate in water or the iodine holes in the solid cake may elute first. However, the sustained-release property is not yet sufficiently satisfactory.

Therefore, an object of the present invention is to provide an environmental bactericidal composition in which iodine is fixed in a solid form which is easy to handle, and which is excellent in sustained release of iodine and sustaining bactericidal action. Another object of the present invention is to provide a method for producing a slime preventive agent for kitchen or toiletry.

Another object of the present invention is that iodophor is fixed in gypsum, and the elution of gypsum and the elution of iodohole are carried out in a balanced manner. As a result, the sustained release of iodine and the antibacterial action are achieved. Another object of the present invention is to provide a method for producing an environmental disinfectant composition, especially a kitchen anti-smudge agent for toiletries or toiletries, which achieves the above-mentioned durability.

Still another object of the present invention is to provide a method for producing a solid environmental disinfectant composition by a simple means and with a small number of steps and with high productivity.

[0010]

According to the present invention, solid environmental sterilization is characterized in that iodophor and α-type hemihydrate gypsum are mixed in the presence of water, and the mixture is molded and cured. A method for producing a drug composition is provided.

As the iodine hole, any one known per se can be used, but povidone iodine is preferable. Iodine holes are 5 to 15%, especially 9 to 1
It is preferable that it has an effective iodine amount of 2% from the viewpoint of bactericidal property.

The iodine content and the α-type hemihydrate gypsum are 2:98 to 50:50, especially 5:95 to 50: based on the solid content.
Mixing in a weight ratio of 50 is preferable from the viewpoint of the combination of strength, antibacterial property and durability of the molded product.

Addition of an organic or inorganic binder or excipient during the molding of the mixture can improve the strength of the solid molded article and the sustained release of iodine.

According to the present invention, the solid molded and cured product obtained by the above method can be impregnated with a solution of a water-soluble or alcohol-soluble iodide and iodine, whereby the antibacterial action is further enhanced. You can also do it.

According to the present invention, it further comprises a solid environmental disinfectant composition obtained by mixing iodophor and α-type hemihydrate gypsum in the presence of water, molding the mixture, and curing the mixture. A slime preventive agent for kitchen or toiletry is provided.

[0016]

BEST MODE FOR CARRYING OUT THE INVENTION The present invention is characterized in that iodine holes and α-type hemihydrate gypsum are mixed in the presence of water, and the mixture is molded and cured.

Gypsum includes dihydrate gypsum, anhydrous gypsum, and hemihydrate gypsum (calcined gypsum) depending on the state of crystal water. In the present invention, α-type hemihydrate gypsum is selected from these gypsums. , Combined with iodine hall.

That is, hemihydrate gypsum is roughly classified into α-type and β-type, and α-type hemihydrate gypsum can be hardened with a smaller amount of mixed water than β-type hemihydrate gypsum. The main feature is that it gives a solid cured product having a dense structure and high strength.

As shown in the examples described below, in the solid environmental disinfectant composition according to the present invention, when the contact with water is continued,
Its outer shape shows a shape similar to that of the first dosage form, and only the size tends to be small.Iodohole is effectively fixed in gypsum, and the dissolution of gypsum and the dissolution of iodine hole are balanced. The result is a sustained release of iodine and a sustained bactericidal action. Also,
It has excellent strength in water and shows no tendency to collapse.
Therefore, it is desirable that the environmental bactericidal composition of the present invention has practically preferable characteristics that it does not disintegrate in water and the elution of iodine holes is continued for 10 days or longer, particularly preferably 20 days or longer. Be done.

When the β-type hemihydrate gypsum is used, even if a cured molded product with iodine holes can be formed, it has low strength in water and tends to disintegrate, and also when disintegration does not occur. However, only iodine holes in the cured gypsum tend to be preferentially dissolved in water (see Comparative Example 2 described later).

According to the present invention, since the iodine hole and the α-type hemihydrate gypsum are mixed in the presence of water, not only the both can be homogeneously and uniformly mixed but also the water content used as the mixing medium can be changed. Since it is possible to cure α-type hemihydrate gypsum by using it, it is possible to produce an extremely homogeneous and dense cured molding,
Moreover, there is an advantage that a solid environmental disinfectant composition can be produced with high productivity by a simple means and with a small number of steps. Further, α-type hemihydrate gypsum gives a merit that it has good moldability because it causes a slight volume expansion during curing.
Further, the environmental bactericidal composition of the present invention, as a bactericidal agent, since it uses an iodine hole that is difficult to corrode metal, for example, over a long period of time also in the kitchen where metal corrosion such as a metal sink is concerned. It has the advantage that it can be installed and is practical.

[Iodophor] In the present invention, as the iodine, any iodine preparation known per se is used, and the iodine is a complex having a bactericidal action but not having an unpleasant odor peculiar to iodine. Made of In this complex, iodine is incorporated in the form of a complex into a carrier composed of a neutral polymer.

As an example, in the case of povidone iodine, the following formula (1)

Embedded image As shown in the structural formula (wherein n is a positive integer),
Polyvinylpyrrolidone and molecular iodine form a complex.

Examples of the carrier polymer of iodophor include, in addition to polyvinylpyrrolidone, polyether glycol, polyvinyl alcohol, polyacrylic acid, polyamide, polyoxyalkylene, cadexomer, poloxamer, cyclodextrin, polyethylene glycol, polymethacrylic acid and the like. I can give you.

As a concrete example of the iodine preparation,
Povidone iodine (polyvinylpyrrolidone iodine complex),
Iodine-alkyl polyether alcohol complex (G.
S. I. ), Polyethoxypolypropoxypolyethoxyethanol / iodine complex (Iocline), nonylphenoxypolyethoxyethanol / iodine complex, polyoxyethylene-added vegetable oil / iodine complex, polyoxyethylene-added fatty acid / iodine complex, polyoxyethylene-added fatty alcohol / Examples thereof include iodine complex, fatty acid amide / iodine complex, and quaternary organic ammonium / iodine complex, with povidone iodine being preferred.

Iodine having an effective iodine content of 5 to 15%, particularly 9 to 12% is advantageous in terms of bactericidal property and its sustainability. When the effective iodine content is less than the above range, The antibacterial property is insufficient, and on the other hand, if the amount exceeds the above range, the stability is low and the odor is unsatisfactory. If the effective iodine amount of iodine is within the above range, the effective iodine amount of the composition is practically effective while maintaining the ratio of the amount of iodine and gypsum in the obtained fungicide composition to a suitable range. Can be maintained within a range.

There are two types of iodine holes available in liquid form and one available in powder form. Both of them can be used in the present invention, but the powder form can control the water content. It is advantageous.

[Gypsum] In the present invention, α-type hemihydrate gypsum is used. As the α-type hemihydrate gypsum, any of α-type hemihydrate gypsum commercially available per se can be used, but the particle size is
Although not particularly limited, those having a thickness of 5 to 200 μm are generally used. If the particle size is small, the amount of mixed water may increase, while if the particle size is large, the strength of the molded and cured product tends to decrease. It is better to use.

The amount of water necessary for hardening the α-type hemihydrate gypsum is theoretically equivalent to 1.5 molecule of water per 1 molecule of the α-type hemihydrate gypsum, but 100 parts by weight of the α-type hemihydrate gypsum is used. Water content (mixed water content) is 20 to 100 parts by weight, especially 3
A range of 5 to 60 parts by weight is suitable. If the water content is lower than the above range, the degree of curing will be insufficient, while if it is higher than the above range, the denseness of the cured molded article will tend to be lost.

[Composition] In the present invention, iodine hole and α
Mold hemihydrate gypsum and preferably based on solids content of 2:98 to 5
Mixing in the presence of water in a weight ratio of 0:50, particularly preferably 5:95 to 50:50.

If the amount of the α-type hemihydrate gypsum to be mixed is lower than the above range, a cured molded article having sufficient strength cannot be obtained, and a satisfactory sustained release property of iodine cannot be obtained. For example, with respect to 100% by weight of a mixture of gypsum and iodine hole (povidone iodine), about 60% iodine hole (povidone iodine) is added.
When mixed in an amount of not less than wt%, it tends to be difficult to obtain a cured molded article having sufficient strength. On the other hand, if the amount of α-type hemihydrate gypsum is larger than the above range, a sufficient iodine concentration cannot be obtained, and a satisfactory bactericidal action and its sustainability cannot be obtained.

In the present invention, the water for hardening the α-type hemihydrate gypsum can be supplied to the mixing system in a form different from that of iodine-hole and α-type hemihydrate-gypsum, and the aqueous solution of α-hemohydrate or α It can be supplied in the form of an aqueous slurry of mold hemihydrate gypsum.

Various additives and auxiliaries can be added to this composition. For example, various binders and excipients can be blended in order to impart strength and compactness to the cured molded article. Examples of these are dextrin, sodium alginate, gum arabic, gelatin, CMC,
Methyl cellulose, PVA, polyvinylpyrrolidone, hydroxypropyl cellulose, corn starch, lignin, water glass, bentonite, pitch, asphalt,
Examples thereof include boric acid, mannitol, calcium silicate and the like.

As agents for delaying the hardening of α-type hemihydrate gypsum, organic compounds such as cloth laver, red seaweed (red algae of the Succulentidae), gelatin, peptone and starch, and inorganic substances such as borax and sodium phosphate are blended. You can As the curing retarder, alkali tartrate, alkali citrate, alkali succinate and the like are also useful.

Although the setting of the α-type hemihydrate gypsum is rapid and generally not necessary, a hardening accelerator may be added when the mixed system contains a substance which delays the hardening. Also, if necessary, zeolite, acid clay, bentonite, magnesium phyllosilicate, zinc phyllosilicate,
It is also possible to add 0.1 to 50 parts by weight of talc, kaolin, calcium carbonate, titanium oxide, alumina, mica, hydrotalcite, sepiolite and the like to 100 parts of α-type hemihydrate gypsum. As the curing accelerator, sulfate is suitable.

[Molding and hardening] Molding and hardening of the iodine hole and the α-type hemihydrate gypsum can be carried out by any means. For example, a molded product can be obtained by kneading this composition, extrusion-molding it, and cutting it to an appropriate size. Moreover, casting molding can be performed by filling the composition with the composition. Furthermore, the composition can be tablet-molded.

The shape of the molded body may be any shape such as spherical shape, tablet shape, columnar shape, prismatic shape, and indefinite shape,
The size of the molded body is 5 to 200 mm in the maximum direction,
In particular, it may be 15 to 50 mm.

The plaster molding can be hardened at room temperature, but may be cooled or heated if necessary. The curing time is not particularly limited, but generally 5 minutes to 30 minutes is suitable.

The resulting molded and cured product can be subjected to various post-treatments, if desired. For example, in order to enhance the bactericidal action, the solid molded and hardened product obtained by the above method can be impregnated with a water-soluble or alcohol-soluble iodide, or a solution of potassium iodide and iodine. According to this method, since iodine is well dissolved in potassium iodide, iodine can be effectively fixed in the gypsum-cured molded article. The appropriate impregnation amount of iodine is 0.1 to 20% by weight.

The environmental bactericide according to the present invention exhibits a useful bactericidal action against various microorganisms. The following microorganisms have been experimentally confirmed to have a bactericidal action. Escherichia coli ( Escherichia coli E. coli), Pseudomonas aeruginosa ( Pseudomonas aeruginosa)
Pseudomonas aeruginosa), Shigella flexneri (Shigella flexneri
Shigella), Salmonella Enteritidis (Salmonel
la enteritidis Salmonella), Klebsiella oxytoca ( Klebsiella oxytoca ), Vibrio parahaemolyticu ( Vibrio parahaemolyticu)
s Vibrio parahaemolyticus), Campylobacter sp. (Ca
mpylobacter sp. campylobacter ), Staphylococcus aureus Staphylococcus aureus , methicillin-resistant Staphylococcus aureus
n-resistant Staphylococcus aureus ), Enterococcus faecalis Enterococcus faecalis ,
Candida albicans ( Candida albicans ).

The environmental disinfectant of the present invention can be used for the purpose of controlling harmful microorganisms in an environment where foods are handled or in an environment such as an office or a home. For example, it is particularly useful as a slime preventive agent for kitchens or toiletries, in which case slimming occurs, and at the site where it is to be prevented, by placing an iodine hole-gypsum cured molding,
The desired preventive effect is obtained.

[0042]

EXAMPLES The measurement in each of the following examples was performed as follows.

Effective Iodine and Iodide Ion Content The disinfecting and sterilizing effect of iodine compounds is iodine (I ₂ ) itself, and therefore, the amount of ionic iodine and the amount of effective iodine other than that ((I ₂ ) Iodine molecule itself)
And must be evaluated by the following method. 1. The amount of effective iodine is obtained by suspending 2 g of the sample powder in 100 ml of water and determining the effective iodine% (Ia) by iodine-starch reaction titration with a 0.005N sodium thiosulfate solution. 2. For iodide ion, 2 g of sample powder was added to 100 ml of water.
Sodium bisulfite solution was added until the color of iodine disappeared, then 10 ml of 0.1N silver nitrate solution and 4 ml of nitric acid were added, and titrated with 0.05N ammonium thiocyanate solution using an appropriate amount of silver nitrate (indicator : Iron ammonium sulfate) to determine the total iodine amount% (I), and the difference of (I)-(Ia) is the iodide ion (%) amount.

Bactericidal activity measurement Peptone 1 g / l, KH as agar medium for assay_TwoP
O_Four 3.0 g / l, K _TwoHPO_Four 0.45 g / l, N
Adjust aCl 4g / l and agar 15g / l to pH6
After applying the mixture, the entire surface is smeared with bacteria, and the center is an environmental bactericidal composition
And culture under constant conditions.Pseudomonas aeruginosa is Pseudomonas aeruginosa IFM301
Use 1. The slime-causing bacteria should not adhere to the sink.
Collect the lump and homogenize it evenly with a Teflon homogenizer.
Use tuned items. After culturing, the zone of inhibition of bacterial growth
The width (mm) is measured. (See Fig. 1)

Metal Corrosion Test Approximately 20 g of the environmental disinfectant composition in an airtight container (1000 ml).
Put a stainless steel spoon, which is a test metal,
Put iron nails, copper nails and 50 ml of water at room temperature (about 2
Observe corrosivity at 0 ° C. The evaluation criteria are shown below. 0 No rust is generated 1 Slight rust is generated 2 Partial rust is generated 3 Rust is generated in most parts

Dissolution measurement of iodine hole [0046] About 20 g of the environmental sterilant composition was placed in a beaker (50 cc) and tap water (about 20 ° C) was continuously poured at a rate of 500 ml / min. The elution degree was determined by measuring the number of days until the center of the cross section was divided into half and turned to white or pale yellow.

(Example 1) 30 g of 7.6 g of ion-exchanged water was added.
A povidone-iodine solution was obtained by dissolving 3 g of povidone-iodine (manufactured by Nihonbo Kagaku) in a plastic container of ml. This povidone iodine solution and 17 g of α-type hemihydrate gypsum (Yoshino Gypsum: Histone B) were mixed thoroughly to give an inner diameter of 30
It was poured into a form of a mm vinyl chloride pipe. After 30 minutes, it is demolded, left at room temperature for 3 hours and then dried in a constant temperature dryer at 60 ° C. for 10 hours to obtain a disc-shaped environmental bactericidal composition having a diameter of 30 mm, a height of 15 mm and a weight of 21.3 g. It was Table 1 shows the effective iodine amount of the above environmental bactericidal composition. Table 2 shows the results of examining the bactericidal activity using Pseudomonas aeruginosa and slime-causing bacteria. Table 3 shows the results of examining the corrosiveness to metals.
It was shown to.

Example 2 6.3 g of ion-exchanged water was added to 30 parts.
A povidone-iodine solution was obtained by taking 6 ml of a povidone-iodine (manufactured by Nihonbo Chemical Co., Ltd.) in a plastic container of ml. This povidone iodine solution and 14 g of α-type hemihydrate gypsum (manufactured by Yoshino Gypsum: Histone B) were thoroughly mixed to give an inner diameter of 30
It was poured into a form of a mm vinyl chloride pipe. After 30 minutes, it is demolded, left at room temperature for 3 hours, and then dried in a constant temperature dryer at 60 ° C. for 10 hours to obtain a disc-shaped environmental bactericidal composition having a diameter of 30 mm, a height of 14 mm and a weight of 20.8 g. It was The effective iodine amount of the above antibacterial composition is shown in Table 1. Table 2 shows the results of examining the bactericidal activity using Pseudomonas aeruginosa and slime-causing bacteria. The results of examining the corrosiveness to metals are shown in Table 3.

(Example 3) 10 g of povidone iodine (manufactured by Nihonho Chemical Co., Ltd.) and 10 g of α-type hemihydrate gypsum (manufactured by Yoshino Gypsum: Histone B) are placed in a 30 ml plastic container and mixed thoroughly. Ion-exchanged water (4.5 g) was added to this mixture, mixed thoroughly, and poured into a mold of a vinyl chloride pipe having an inner diameter of 30 mm. After 30 minutes, demold, leave at room temperature for 3 hours, and then dry in a constant temperature dryer at 60 ° C for 10 hours to give a diameter of 30
A disc-shaped environmental disinfectant composition having a size of mm, a height of 13 mm, and a weight of 20.1 g was obtained. The effective iodine amount of the above antibacterial composition is shown in Table 1. Table 2 shows the results of examining the antibacterial activity using Pseudomonas aeruginosa and slime-causing bacteria. The results of examining the corrosiveness to metals are shown in Table 3.

(Example 4) 30 g of 8.8 g of ion-exchanged water was added.
A povidone-iodine solution was obtained by dissolving 0.5 g of the povidone-iodine (manufactured by Nihonbo Kagaku) in a ml plastic container. 19.5 g of this povidone iodine solution and α-type hemihydrate gypsum (manufactured by Yoshino Gypsum: Histone B) are thoroughly mixed,
It was poured into a vinyl chloride pipe mold having an inner diameter of 30 mm. After 30 minutes, it is demolded, left at room temperature for 3 hours, and then dried in a constant temperature dryer at 60 ° C. for 10 hours. Diameter 30 mm, height 15
A disc-shaped environmental disinfectant composition having a size of 21.9 g and a weight of 21.9 g was obtained. Table 1 shows the effective iodine amount of the above environmental bactericidal composition. Table 2 shows the bactericidal activity of Pseudomonas aeruginosa and slime-causing bacteria.

(Example 5) 30 g of 8.9 g of ion-exchanged water was added.
A povidone-iodine solution was obtained by dissolving 0.2 g of povidone-iodine (manufactured by Nihonbo Chemical Co., Ltd.) in a ml plastic container. This povidone iodine solution and 19.8 g of α-type hemihydrate gypsum (Yoshino Gypsum: Histone B) are mixed thoroughly,
It was poured into a vinyl chloride pipe mold having an inner diameter of 30 mm. After 30 minutes, it is demolded, left at room temperature for 3 hours, and then dried in a constant temperature dryer at 60 ° C. for 10 hours. Diameter 30 mm, height 15
A disc-shaped environmental bactericidal composition having a weight of 22.6 g was obtained. The effective iodine amount of the above antibacterial composition is shown in Table 1.
The antibacterial activity was examined using Pseudomonas aeruginosa and slime-causing bacteria. Table 2 shows the results. Corrosion resistance to metals is shown in Table 3.

(Comparative Example 1) 14 g of trichloroisocyanuric acid (reagent first grade), 4 g of α-type hemihydrate gypsum (Yoshino Gypsum: Histone B), and 2 g of boric acid as a binder were sufficiently mixed to give an inner diameter of 25 mm and high It is packed in a vinyl chloride pipe of 22 mm in length, and 5 times by using a hydraulic press machine.
A ton of pressure was applied to obtain a molded product having a diameter of 3 cm and a height of 14 mm. Table 3 shows the results of examining the corrosiveness to metals.
It was shown to.

Comparative Example 2 13 g of ion-exchanged water was added to 30 m
Into a plastic container (1), 3 g of povidone iodine (manufactured by Nihonbo Kagaku Co., Ltd.) was dissolved to obtain a povidone iodine solution. This povidone iodine solution and 17 g of β-type hemihydrate gypsum (Yoshino Gypsum: Class A) were thoroughly mixed and poured into a mold of a vinyl chloride pipe having an inner diameter of 30 mm. After 30 minutes, demold,
After leaving it for 3 hours at room temperature, it was dried for 10 hours in a constant temperature dryer at 60 ° C, diameter 30 mm, height 15 mm, weight 22.1 g.
To obtain a disc-shaped antibacterial composition. Table 1 shows the effective iodine amount and povidone iodine elution amount of the above environmental bactericidal composition. The results of examining the corrosiveness to metals are shown in Table 3.

[0054]

[Table 1]

[0055]

[Table 2]

[0056]

[Table 3]

From Table 1, in the environmental disinfectant composition of the present invention using α-type hemihydrate gypsum (Examples 1 to 5), the iodine hole elution rate is 10 days or more, while β
It can be understood that the environmental sterilant composition using the mold hemihydrate gypsum (Comparative Example 2) has an iodine hole elution degree of about 7 days. That is, it can be understood that the composition of the present invention using α-type hemihydrate gypsum is more practical in terms of iodine hole elution rate than the composition of Comparative Example 2 using β-type hemihydrate gypsum. From Table 2, it can be understood that the environmental bactericidal composition of the present invention has good bactericidal activity. From Table 3, in the metal corrosion test, when iodine hole was used as the bactericide component, no rust was generated in the sample, or slight rust was generated in the sample only in a specific case where the sample was tested as iron for 5 days or more. While giving a good result of the degree of occurrence,
When trichloroisocyanuric acid was used as the disinfectant component, rust could not be avoided in any of iron, copper and stainless steel. That is, the composition of the present invention which uses iodine as a bactericide is also excellent in metal corrosiveness.

[0058]

INDUSTRIAL APPLICABILITY According to the present invention, there is provided an environmental bactericidal composition in which iodine is fixed in a solid form which is easy to handle, and which is excellent in sustained release of iodine and sustaining bactericidal action. To be done. In this composition, iodophor is fixed in gypsum, and the elution of gypsum and the elution of iodohole are performed in a balanced manner, so that sustained release of iodine and sustaining antibacterial action are achieved. Therefore, this composition is particularly useful as an anti-smudge agent for kitchens or toiletries. In addition, since this environmental disinfectant composition uses iodine holes that are unlikely to corrode metals as a disinfectant, for example, it should be installed for a long period of time in kitchens where metal corrosion such as metal sinks is concerned. Is possible and has excellent practicality. The environmental bactericidal composition of the present invention can be produced by a simple means of mixing iodine hole and α-type hemihydrate gypsum in the presence of water and curing the mixture to form a solid with a small number of steps. . Therefore, this composition and its manufacturing method are excellent in productivity.

[Brief description of the drawings]

FIG. 1 is a diagram for explaining the inhibition zone width of bacterial growth.

[Explanation of symbols]

 1 Petri dish 2: Environmental disinfectant composition 3: Inhibitory zone width (mm) for growth of bacteria 4: Colony of bacteria

 ─────────────────────────────────────────────────── ─── Continuation of the front page (72) Inventor Gan Iwako 3-3-3 Nihombashi Muromachi, Chuo-ku, Tokyo Within Nihonho Chemical Co., Ltd. (72) Masanori Tanaka 4-1-21, Nihombashi Muromachi, Chuo-ku, Tokyo No. Mizusawa Chemical Co., Ltd. (72) Inventor Kiyoshi Watanabe 4-1-21, Nihombashi Muromachi, Chuo-ku, Tokyo Mizusawa Chemical Co., Ltd.

Claims (7)

[Claims] 1. A method for producing a solid environmental disinfectant composition, which comprises mixing iodophor and α-type hemihydrate gypsum in the presence of water, molding the mixture, and curing the mixture. 2. The method according to claim 1, wherein the iodine hole is povidone iodine. 3. The method according to claim 1, wherein the iodine hole has an effective iodine amount of 5 to 15%. 4. The method according to claim 1, wherein the iodine hole and the α-type hemihydrate gypsum are mixed in a weight ratio of 2:98 to 50:50 on the basis of the solid content. 5. The production method according to claim 1, wherein an organic or inorganic binder or excipient is added when the mixture is molded. 6. An environmental sterilization characterized by impregnating a solid molded and cured product obtained by the method according to claim 1 with a solution of a water-soluble or alcohol-soluble iodide and iodine. For producing a pharmaceutical composition. 7. A kitchen or a kitchen characterized by comprising a solid environmental disinfectant composition obtained by mixing iodine hole and α-type hemihydrate gypsum in the presence of water, molding the mixture, and curing the mixture. Anti-slip agent for toiletries.