JPH09110892A - Trehalose hydroxyaliphatic ether - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain the subject stable new carbohydrate compound extremely high in safety, and useful as e.g. a surfactant excellent in foamability, cleansing power and touch feeling, thus to be used in cosmetics, cleansing agent compositions, etc. SOLUTION: This compound is a new trehalose hydroxyaliphatic ether expressed by the formula (A is a residue resulted from eliminating n hydroxyl groups from trehalose; R is a 6-30C alkyl; (n) is 1 or 2), being stable and extremely safe, used as e.g. a surfactant excellent in functions such as foamability and cleansing power and in touch feeling when used, thus useful for e.g. cosmetics and cleansing agent compositions. This compound is obtained by the following process: trehalose and sodium hydroxide are dissolved in dimethyl sulfoxide followed by agitating the resultant solution under a pressure of 10mmHg at 80 deg.C for 30min and then distilling off the water contained, and e.g. 1,2-epoxyhexadecane is dripped into the resultant system followed by agitation at 110 deg.C for 4h and then neutralization, and the product is allowed to flow through an adsorptive resin column, the adsorbed matter is then eluted with a 60% aqueous ethanol solution.

Description

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The present invention relates to a novel compound, trehalose hydroxyaliphatic ether, a surfactant comprising trehalose hydroxyaliphatic ether, and trehalose hydroxyaliphatic ether. Agent composition.

[0002]

2. Description of the Related Art Generally, the conditions that cosmetic raw materials must have are functions (for example, cleaning power and foaming power in the case of cleaning agents), good safety, good stability, and industrial stability. There is something like that. Conventionally, many cosmetics use a surfactant for the purpose of emulsification, solubilization, dispersion, washing, etc., but in addition to the above-mentioned conditions, it may have a feeling of use depending on the purpose of the product. It is an important condition.

Conventionally, for many cosmetics, emulsification, solubilization,
For the purpose of dispersion and washing, anionic surfactants such as lauryl sulfate ester salt, POE (polyoxyethylene) alkyl ether sulfate salt, acylated amino acid salt and soap have been mainly used.

However, these anionic surfactants are superior in foamability and the like as compared with nonionic surfactants, but are inferior in safety. Therefore, various nonionic surfactants have been investigated, but they are not necessarily satisfactory in terms of foaming power. For example, in the case of POE alkyl ether, safety such as skin irritation is good, but foaming property is poor. Among nonionic surfactants, sugar derivatives are substances having excellent foaming properties. As the sugar derivative, an alkyl glycoside,
There are sucrose fatty acid ester, maltitol hydroxyalkyl ether, and the like, and these have considerably close foaming properties and the like and are excellent in safety as compared with the above-mentioned anionic surfactants.

The degree of polymerization of alkyl glycosides is about 1.
The problem is that the hydrophilicity is 5, the hydrophilicity is poor, the glucose contained as an impurity reacts with an amino compound or the like to turn brown, and the foam is light and the creaminess is insufficient. Sucrose fatty acid ester is related to the chain length of fatty acid and has relatively good foamability, but it decomposes over time except when the pH is around neutral, especially hydrolysis of ester bond, and glycoside bond. It has a problem that hydrolysis of is likely to occur.

Maltitol hydroxyalkyl ether has relatively good safety, foaming property and stability,
Maltitol has three primary hydroxyl groups in the molecule, and etherification mainly occurs at these sites, so that polyether is likely to be generated, which is a factor that hinders functions such as foamability. In addition, there is a problem that removal and purification of the polyether are expensive.

The inventors of the present invention have made extensive studies in view of the above circumstances, and as a result, there are only two primary hydroxyl groups of trehalose, so that trehalose hydroxyaliphatic ethers containing a mono-form and a di-form as a main component are obtained. Since the hemiacetal part, which is a stabilizing factor, is blocked by a bond, when used as a cosmetics and detergent composition, it is less colored and decomposed over time, and has excellent emulsification and foaming properties as a surfactant. They found that they have a function, and completed the present invention.

[0008]

That is, the present invention provides a trehalose hydroxyaliphatic ether represented by the general formula "Chemical Formula 2".

Embedded image (In the formula, A is a residue obtained by removing n hydroxyl groups from trehalose, R is a linear or branched alkyl group having 6 to 30 carbon atoms, and n is an integer of 1 or 2.)

The present invention also provides a surfactant comprising a trehalose hydroxyaliphatic ether represented by the general formula "Chemical Formula 2".

Furthermore, the present invention provides a cosmetic characterized by containing a trehalose hydroxyaliphatic ether represented by the general formula "Chemical Formula 2".

The present invention also provides a detergent composition comprising a trehalose hydroxyaliphatic ether represented by the general formula "Chemical Formula 2".

Hereinafter, the present invention will be described in detail. In the general formula "Chemical Formula 2", A is a residue obtained by removing n hydroxyl groups from trehalose, and R is a linear or branched alkyl group having 6 to 30, preferably 8 to 18 carbon atoms. . When the total number of carbon atoms of R is out of the range of 6 to 30, the balance between hydrophilicity and hydrophobicity is lost and the surface activity is lowered. Such trehalose hydroxyaliphatic ether is excellent in safety and stability, and has functions such as surface activity such as detergency, dispersibility, emulsification and solubilization, and moisturizing properties, and therefore, cosmetics and detergent compositions. It can be mixed with other things.

Specific examples of R include hexyl group, heptyl group, octyl group, decyl group, lauryl group, myristyl group, palmityl group, stearyl group, eicosyl group, behenyl group and isostearyl group. Further, n is an integer of 1 or 2, and means a mono- or di-form hydroxyaliphatic ether of trehalose.

The trehalose hydroxyaliphatic ether of the present invention can be synthesized by the following method.

Dissolve trehalose and alkalis such as sodium hydroxide with dimethyl sulfoxide or the like,
Dehydrate with stirring. Epoxy alkane is added to this, and it is made to react. After the reaction is complete, an equivalent amount of hydrochloric acid is added to neutralize the mixture, and column chromatography is performed to obtain trehalose hydroxyaliphatic ether.

The trehalose hydroxyaliphatic ether is an excellent surfactant that is chemically stable, extremely safe, and has excellent foaming power, detergency and usability. As a result, excellent cosmetic and detergent compositions can be obtained.

The amount of trehalose hydroxyaliphatic ether compounded in the cosmetic and detergent composition of the present invention is not particularly limited, but is usually 0.01 to 30.0% by weight, preferably 0.1 to 10.0. % By weight is compounded.

The cosmetic composition and detergent composition of the present invention has detergency, emulsifying property, dispersibility, and moisturizing property by incorporating trehalose hydroxyaliphatic ether, and is excellent in safety and stability. Reduces the irritation of other ingredients inside,
Improves system stability and moisture retention.

In addition to the above-mentioned essential component trehalose hydroxyaliphatic ether, the cosmetic and detergent composition of the present invention may optionally contain, if necessary, other components usually used in cosmetics and detergents. it can.

For example, hydrocarbons such as liquid paraffin, squalane and vaseline, oils and fats such as macadamia nut oil and olive oil, waxes such as lanolin and jojoba oil, silicones such as dimethylpolysiloxane and methylphenylsiloxane, capryl alcohol and lauryl. Higher alcohols such as alcohol, myristyl alcohol, cetyl alcohol, cholesterol, phytosterol, capric acid, myristic acid, palmitic acid, stearic acid, behenic acid, lanolin fatty acid, linoleic acid, higher fatty acid such as linolenic acid, paraaminobenzoic acid, homomenthyl -7N
-Acetylanthranilate, butylmethoxybenzoylmethane, di-paramethoxycinnamic acid-glyceryl mono-2-ethylhexanoate, amyl salicylate, octylcinnamate, UV absorbers such as 2,4-dihydroxybenzophenone, polyethylene glycol, glycerin , 1,3-butylene glycol, erythritol, sorbitol, xylitol, maltitol, mucopolysaccharide,
Moisturizers such as hyaluronic acid, chondroitin sulfate and chitosan, thickeners such as gum arabic, polyvinyl alcohol, montmorillonite and laponite, lower alcohols such as ethanol, butylhydroxytoluene, tocopherol, antioxidants such as phytic acid, benzoic acid , Salicylic acid, sorbic acid, paraoxybenzoic acid alkyl ester, antibacterial agents such as hexachlorophene, glycine, alanine, valine, leucine, threonine, phenylalanine, tyrosine, aspartic acid, asparagine, glutamine, taurine, arginine, histidine and other amino acids and these Alkali metal salts and hydrochlorides, organic acids such as acyl sarcosine acid (eg sodium lauroyl sarcosine), glutathione, citric acid, malic acid, tartaric acid, lactic acid, vitamin A and its Conductor, vitamin B6 hydrochloride,
Vitamin B6 tripalmitate, vitamin B6 dioctanoate, vitamin B2 and its derivatives, vitamin B1
2. Vitamin Bs such as vitamin B15 and its derivatives,
Ascorbic acid, ascorbic acid sulfate (salt),
Vitamin Cs such as ascorbic acid phosphate (salt) and ascorbic acid dipalmitate, α-tocopherol, β-tocopherol, γ-tocopherol, vitamin E such as vitamin E acetate, vitamin Ds, vitamin H, pantothenic acid, pantethine Vitamins such as nicotinic acid amide, benzyl nicotinate, γ-oryzanol, allantoin, glycyrrhizinic acid (salt), glycyrrhetinic acid and its derivatives, hinokitiol, bisabolol, eucalptone, thymol, inositol, saikosaponin, carrot saponin, and loofah. Saponins, saponins such as muclodisaponin, pantothenyl ether, ethinyl estradiol, tranexamic acid, arbutin, cepharantin, placenta extract, etc. , Organic solvent such as, kohone, orange, sage, yarrow, mallow, assembly, thyme, spruce, spruce, birch, horsetail, loofah, horse chestnut, yukinoshita, arnica, lily, mugwort, peony, aloe, gardenia, sawara, alcohol, many Natural extract extracted with polyhydric alcohol, water, aqueous alcohol, etc., pigment, sorbitan monolaurate, sorbitan monopalmitate, sorbitan sesquioleate, sorbitan trioleate, polyoxyethylene sorbitan monolaurate, polyoxyethylene glycol monooleate, poly Oxyethylene alkyl ether, polyethylene glycol difatty acid ester, lauroyl diethanol amide, fatty acid dipropanol amide, maltitol hydroxy aliphatic ether, alkylation Nonionic surfactants such as polysaccharides, alkyl glucosides, sugar esters, polyether modified silicones, stearyl trimethyl ammonium chloride, benzalkonium chloride,
Cationic surfactant such as lauryl amine oxide, sodium palmitate, sodium laurate, sodium lauryl sulfate, potassium lauryl sulfate, triethanolamine alkylsulfate, anionic surfactant such as acylmethyl taurine salt, amphoteric surfactant, neutralization Agents, antioxidants, pigments, fragrances, purified water and the like can be added.

The cosmetics referred to in the present invention mean all cosmetics such as aqueous solution type, solubilizing type, emulsifying type, powder dispersion type, water-oil two-layer system, water-oil-powder three-layer system, It also has a wide variety of uses, including basic cosmetics such as lotions, emulsions, creams and packs, makeup cosmetics such as lipsticks and foundations, and hair cosmetics such as shampoos, rinses and hair tonics. The thus-obtained cosmetic composition has good stability over time in the system and exhibits a rich feel during use.

The cleaning composition according to the present invention is a composition for cleaning a certain thing, and its application is not limited, and examples thereof include shampoo, solid soap, liquid soap, toothpaste, kitchen detergent. And so on.

Hereinafter, the present invention will be described in more detail with reference to examples. Note that the present invention is not limited to these.

[Example 1] Production of trehalose hydroxyhexadecyl ether 49.6 g of trehalose and 2.2 g of sodium hydroxide were dissolved in 160 ml of dimethyl sulfoxide, and 10 mmH was used.
After water was distilled off while stirring at 80 ° C. for 30 minutes, 11.5 g of 1,2-epoxyhexadecane was added dropwise, and the mixture was further stirred at 110 ° C. for 4 hours. After completion of the reaction, an equivalent amount of hydrochloric acid was added to neutralize the mixture, and the mixture was suspended in water to prepare a hyperporous polymer (Diaion HP2
0, manufactured by Mitsubishi Kagaku Co., Ltd.), and then passed through water first, then 30% ethanol aqueous solution and then 60% ethanol aqueous solution in that order, and the 60% ethanol aqueous solution is fractionated. Purified. Then, 17.9 g of trehalose hydroxyhexadecyl ether was obtained. This fraction was developed by silica gel thin-layer chromatography using hexane-ethyl acetate (8: 2) to find one spot, and the Rf value was located almost in the middle of the raw materials. Figure-
The IR spectrum is shown in Fig. ¹ , which is 2922 cm ^-1 and 2
Absorbing represents an alkyl group 852cm ^-1 and 1100 cm ^-1
Had absorption derived from the CO group. ¹³ C in Fig. 2
Although it showed NMR, it had a signal derived from an alkyl group and a sugar chain.

[Example 2] Preparation of trehalose hydroxydodecyl ether 52.3 g of trehalose and 2.3 g of sodium hydroxide were dissolved in 160 ml of dimethyl sulfoxide, and 10 mmH was used.
g, after removing water by stirring at 80 ° C. for 30 minutes, 9.7 g of 1,2-epoxydodecane was added dropwise,
Furthermore, it stirred at 110 degreeC for 4 hours. After completion of the reaction, an equivalent amount of hydrochloric acid was added to neutralize the mixture, and the mixture was suspended in water and passed through a column using a hyperporous polymer (Diaion HP20, manufactured by Mitsubishi Chemical Corporation) with water at first. Then, 30% ethanol aqueous solution and 60% ethanol aqueous solution were passed in this order, and the solution of 60% ethanol aqueous solution was collected to purify. Then, 20.2 g of trehalose hydroxydodecyl ether was obtained. This fraction was subjected to silica gel thin-layer chromatography using hexane-ethyl acetate (8: 2) to find 1 spot.

[Example 3] Production of trehalose hydroxytetradecyl ether 47.3 g of trehalose and 2.1 g of sodium hydroxide were dissolved in 160 ml of dimethyl sulfoxide, and 10 mmH was used.
After water was distilled off while stirring at 80 ° C. for 30 minutes, 1,2-epoxytetradecane (10.1 g) was added dropwise, and the mixture was further stirred at 110 ° C. for 4 hours. After completion of the reaction, an equivalent amount of hydrochloric acid was added to neutralize the mixture, and the mixture was suspended in water to prepare a hyperporous polymer (Diaion HP2
0, manufactured by Mitsubishi Kagaku Co., Ltd.), and then passed through water first, then 30% ethanol aqueous solution and then 60% ethanol aqueous solution in that order, and the 60% ethanol aqueous solution is fractionated. Purified. Then, 16.3 g of trehalose hydroxytetradecyl ether was obtained. This fraction was subjected to silica gel thin-layer chromatography using hexane-ethyl acetate (8: 2) to find 1 spot.

The effect of the trehalose hydroxydodecyl ether obtained above as a cosmetic and detergent composition was evaluated according to the following test methods and evaluation methods.

"Foaming power test" CaCO ₃ 70 ppm artificial hard water, 40 ml of a 1% sample concentration solution was prepared, and the temperature was 40%.
The amount of foaming was measured using a cylindrical cylinder equipped with a stirrer under the condition of ° C. The evaluation was performed according to the following three-stage evaluation. ◯: Good foaming (foam amount 2000 ml or more) Δ: Normal foaming (foam amount 1500 ml or more and less than 2000 ml) X: Poor foaming (foam amount 1500 ml or less)

"Cleanability test" CaO / MgO = 3/1.
A solution having a sample concentration of 1% was prepared with 5 DH artificial hard water, and the artificial sebum-contaminated cloth using wool surge was washed. Temperature 40 ℃
Washing was carried out using a Terg-O-tometer (JISK-3371) under the conditions of, and the washing efficiency was obtained from the reflectance before and after washing. Detergency ratio _{(%) = (R W -R} S) / (R O -R S) × 100 R O: reflectance R _S of the original cloth (wool serge): reflectance R _W of stained cloth before washing: washed The subsequent evaluation of the reflectance of the contaminated cloth was performed by the following three-stage evaluation. ◯: Good washability (washing efficiency of 80% or more) Δ: Normal washability (washing efficiency of 60% or more and less than 80%) ×: Poor washability (washing efficiency of less than 60%)

[Hand rough test] 10 males and 10 females for each sample
Using a panel of 20 people in total, the left hand is immersed in an aqueous solution with a sample concentration of 5% at a temperature of 35 ° C and the right hand is immersed in water of the same temperature for 10 minutes, and then washed with hot water twice a day for 3 days. After continuing, the difference in rough skin condition was visually evaluated. The evaluation was performed according to the following four-level evaluation. ◎: Remarkably weak hand roughness (0 to 2 out of 20 people with rough hand on the sample side) ○: Moderate weakness (4 to 8 out of 20 people with rough hand on the sample side) Δ: Slightly rough (10 to 14 out of 20 people with rough hands on the sample side) ×: Remarkably strong rough hands (16 to 20 out of 20 people with rough hands on the sample side)

"Stickiness sensory test" Sample concentration 10% each
A total of 60 men and women, 30 men and women, were asked to wash their hands with an aqueous solution to determine the stickiness, and the number of people was used to determine the stickiness. The evaluation was performed according to the following three-stage evaluation. ○: less than 5 people felt sticky △: 5 or more and less than 30 people felt sticky ×: 30 or more people felt sticky

The above results are shown in "Table 1".

[Table 1] Comparative Example 1: Sodium Lauryl Sulfate Comparative Example 2: Glucose Polymerization Degree Average 1.4 and Alkyl Composition C ₁₂ : C
₁₄ : C ₁₆ = 68: 26: 6 alkylglycoside)

From these results, the trehalose hydroxyaliphatic ether of the present invention is not only stable and safe as compared with conventional saccharide surfactants, but is also excellent in detergency, foamability and usability. I found out.

Examples of cosmetic and detergent compositions are shown below. "Example 4" Emulsion weight% (1) Stearic acid 2.0 (2) Cetyl alcohol 0.8 (3) Squalane 10.0 (4) Vaseline 2.0 (5) Trehalose hydroxyhexadecyl ether 1.0 ( 6) Lanolin 2.0 (7) α-tocopherol acetate 0.05 (8) Perfume proper amount (9) Propylene glycol 5.0 (10) Triethanolamine 1.0 (11) Carboxyvinyl polymer 0.1 (12) ) Ion-exchanged water

[Example 5] Lotion% (1) Glycerin 3.0 (2) Propylene glycol 4.0 (3) Oleyl alcohol 0.1 (4) Trehalose hydroxytetradecyl ether 1.5 (5) Ethanol 10.0 (6) Appropriate amount of perfume (7) Appropriate amount of preservative (8) Residual amount of deionized water

Example 6 Base Cream Weight% (1) Stearic Acid 0.5 (2) Stearyl Alcohol 1.0 (3) Vaseline 2.0 (4) Methyl Polysiloxane 2.0 (5) Liquid Paraffin 5 0.0 (6) Batyl alcohol 1.5 (7) Trehalose hydroxyoctadecyl ether 2.0 (8) Preservative proper amount (9) Perfume proper amount (10) Carboxyvinyl polymer proper amount (11) Glycerin 5.0 (12) ) Ethanol 7.0 (13) Ion-exchanged water Residual (14) Potassium hydroxide 0.1

[Example 7] Emulsion foundation weight% (1) 1,3 butylene glycol 5.0 (2) bentonite 1.0 (3) trehalose hydroxyoctadecyl ether 2.0 (4) potassium hydroxide 0.1 ( 5) Vaseline 2.0 (6) Liquid paraffin 10.0 (7) Cetanol 2.0 (8) Monooleyl glyceryl ether 2.0 (9) Isopropyl myristate 2.0 (10) Preservative proper amount (11) Fragrance Suitable amount (12) Formulated powder * 20.0 (13) Ion-exchanged water Residual *: Titanium oxide 8, Kaolin 5, Talc 6, Iron oxide 1

“Example 8” Lipstick wt% (1) Castor oil 45.0 (2) Hexadecyl alcohol 25.0 (3) Lanolin 4.0 (4) Beeswax 4.0 (5) Ozokerite 3.0 (6) Candelilla wax 6.0 (7) Carnauba wax 2.0 (8) Trehalose hydroxytetradecyl ether 3.0 (9) Antioxidant proper amount (10) Preservative proper amount (11) Titanium oxide 2.0 (12) Red No. 202 0.5 (13) Red No. 204 2.5 (14) Red No. 227 A1 Rake 2.5 (15) Orange No. 201 O.I. 2 (16) Perfume proper amount

“Example 9” Shampoo Weight% (1) Sodium lauryl sulfate 5.0 (2) Betaine alkyldimethylaminoacetate 2.0 (3) Trehalose hydroxydodecyl ether 10.0 (4) Coconut oil fatty acid diethanolamide 3 0.0 (5) Perfume proper amount (6) EDTA-2Na proper amount (7) Ion-exchanged water balance

[Example 10] Body shampoo wt% (1) Potassium laurate 40.0 (2) Trehalose monohydroxyoctyl ether 7.0 (3) Tranexamic acid 2.0 (4) Water-soluble lanolin 2.0 ( 5) Ion-exchanged water 49.0 (6) Suitable amount of perfume (7) Suitable amount of preservative

“Example 11” Wheat toothpaste weight% (1) Magnesium carbonate 40.0 (2) Trehalose hydroxyhexadecyl ether 6.0 (3) Glycerin 40.0 (4) Sweetener Suitable amount (5) Flavor suitable Amount (6) Preservative Appropriate amount

“Example 12” Solid soap weight% (1) Beef tallow 20.0 (2) Coconut oil 12.0 (3) Castor oil 5.0 (4) Olive oil 3.0 (5) Sodium hydroxide 6 0.0 (6) Ethanol 20.0 (7) Maltitol hydroxyhexadecyl ether 4.0 (8) Trehalose hydroxytetradecyl ether 1.0 (9) Glycerin 5.0 (10) Sucrose 10.0 (11) Cyclohexylguanidine 3.0 (12) EDTA 0.1 (13) Perfume proper amount (14) Dye proper amount (15) Ion-exchanged water residue

Example 13 Liquid Soap Weight% (1) Lauric Acid 3.0 (2) Myristic Acid 7.0 (3) Palmitic Acid 3.0 (4) Oleic Acid 2.5 (5) Lauroyldiethanol Amide 6.0 (6) Propylene glycol 11.0 (7) Erythritol 4.0 (8) Trehalose hydroxydodecyl ether 10.0 (9) Laurate N-methyl taurine triethanolamine salt 3.0 (10) Sucrose 5 0.0 (11) Sodium hydroxide 3.0 (12) EDTA 0.1 (13) p-aminobenzamidine 1.0 (14) Perfume proper amount (15) Ion-exchanged water balance

[Example 14] Kitchen detergent wt% (1) Sodium α-oleinsulfonate 20.0 (2) POE (15 mol) alkyl ether 8.0 (3) Laurylamidopropyl betaine 5.0 (4) ) Ethanol 1.5 (5) Dye proper amount (6) Perfume proper amount (7) Trehalose hydroxydodecyl ether 10.0 (8) Glyceryl sulfate sodium laurate 3.0 (9) Deionized water residue

The cosmetics of Examples 4 to 8 are excellent in stability, safety and usability, and the detergent compositions of Examples 9 to 14 are stable, safety, foaming power, detergency and usability. It was an excellent cleaning composition.

[0046]

EFFECTS OF THE INVENTION The surfactant of the present invention comprising a trehalose hydroxyaliphatic ether, and the cosmetic and detergent composition containing the same are stable and have extremely high safety, and functions such as foaming power and detergency. It also has an excellent feeling in use.

[Brief description of the drawings]

FIG. 1 is an IR spectrum diagram of trehalose hydroxyhexadecyl ether produced in Example 1.

FIG. 2 is a ¹³ C-NMR spectrum diagram of trehalose hydroxyhexadecyl ether produced in Example 1.

─────────────────────────────────────────────────── ─── Continuation of the front page (51) Int.Cl. ⁶ Identification code Internal reference number FI Technical display location C07H 3/04 C07H 3/04 C11D 1/68 C11D 1/68

Claims (4)

[Claims] 1. A trehalose hydroxyaliphatic ether represented by the general formula "Chemical Formula 1". Embedded image (In the formula, A is a residue obtained by removing n hydroxyl groups from trehalose, R is a linear or branched alkyl group having 6 to 30 carbon atoms, and n is an integer of 1 or 2.) 2. A surfactant comprising a trehalose hydroxyaliphatic ether represented by the general formula "Chemical formula 1". 3. A cosmetic comprising a trehalose hydroxyaliphatic ether represented by the general formula "Chemical formula 1". 4. A detergent composition comprising a trehalose hydroxyaliphatic ether represented by the general formula "Chemical formula 1".