JPH0880347A - Medicinal liquid injector - Google Patents

Abstract

PURPOSE: To provide a medicinal liquid injector which is capable of continuously dosing an adequate amt. of a medicinal liquid and is simple by providing this injector with a medicinal liquid injecting part having a needle projected perpendicularly from a flatly arranged medicinal liquid storage part and a medicinal liquid transfer means for transferring the medicinal liquid in this medicinal liquid storage part to the medicinal liquid injecting part. CONSTITUTION: The medicinal liquid 1 is stored in the spirally formed tubular plane medicinal liquid storage part 2. The one end of the medicinal liquid storage part 2 is provided with the medicinal liquid injecting part 4 having, for example, three pieces of the needle 3. The needles 3 are projected in the direction perpendicular to the flatly arranged medicinal liquid storage part 2. A highly water absorptive material 5 and water 6 are packed in the terminal part of the medicinal liquid storage part 2. This highly water absorptive material 5 and the water 6 have a function as a transfer part to gradually extrude the medicinal liquid 1 outside from the needles 3. The highly water absorptive material 5 induces volumetric expansion by internally absorbing the water 6 when the material comes into contact with the water. The medicinal liquid 1 is transferred by the expanding force generated in such a manner. The adequate amt. of the medicinal liquid is continuously injected without a fluctuation in its flow rate by providing the flat medicinal liquid storage part 2 with the needles 3 in the direction perpendicular thereto.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an apparatus for continuously injecting a chemical solution in minute amounts.

[0002]

2. Description of the Related Art It is required in various fields to continuously inject a chemical solution into an object to be injected in minute amounts.

For example, for the treatment of diabetes, diet therapy, exercise therapy, insulin (insulin) therapy and the like are carried out depending on its symptoms. Of these, insulin therapy is a therapy in which insulin (insulin), which decomposes glucose in blood, is directly administered to patients who have difficulty controlling their blood glucose levels sufficiently even with therapy such as diet control, weight control, and exercise. Insulin is a protein having a molecular weight of 5807, is hardly absorbed from the skin, and is decomposed in the stomach even if it is orally administered as it is. Therefore, insulin is usually administered by subcutaneous injection. Also, in many cases, under the guidance of a doctor, the patient himself or herself regularly injects an appropriate amount of insulin according to the intake of sugar (2 to 4 times a day),
Performs blood sugar self-regulation. However, this insulin therapy by self-injection has a problem that the physical pain of the patient is great and troublesome for a long period of time. Moreover, since the patient himself / herself injects, there is a risk of overdose rather causing hypoglycemia. Further, hardening of the injection site due to frequent injections, contamination by bacteria, and the like pose problems.

Nasal agents, suppositories, etc. have been proposed as insulin administration methods for solving the above-mentioned problem of self-injection. However, due to problems such as insufficient efficiency, weak blood glucose lowering effect and side effects, it has not yet been put to practical use. It also contains an absorption enhancer together with insulin,
A patch for administration through the skin has also been proposed. However, as described above, transdermal insulin absorption efficiency is poor, and there are problems such as insufficient injection into the body and problems of irritation of the absorption enhancer to the skin, and this has not been put into practical use either. Therefore, although the current insulin therapy has physical pain and other problems, the insulin administration method by self-injection is adopted.

As described above, insulin administration by self-injection causes great physical pain to the patient, and there is a high risk of causing hypoglycemia by excessive administration. In addition, the insulin administration method that does not use a syringe has a problem that the blood glucose lowering effect is not sufficient. Therefore, a simple drug injection device capable of continuously administering an appropriate amount of insulin has been demanded.

Further, when a chemical solution is given to a plant in order to exterminate pests and cure diseases, a method of spraying the chemical solution with a sprayer or mixing the chemical solution into the root soil like fertilizer is used. However, when spraying with a sprayer, there is a problem in that the chemical solution is sprayed on the plants other than the target plant because the chemical solution scatters. In addition, there is a problem that when it is mixed with soil like fertilizer, the drug remains and pollutes the soil. Moreover,
Since the effect is transient, there is a problem that the treatment must be repeated, and there is also a problem that an excessive amount of chemical solution is used. Therefore, there is a demand for a simple drug solution injector that can continuously administer an appropriate amount of drug solution.

Further, the chemical solution may be sprayed for controlling harmful insects such as mites generated on tatami mats and carpets, and for removing and reducing unpleasant odors caused by molds generated on filters of air conditioners. However, since the effect is transient and the treatment must be repeated periodically, a simple drug injection device capable of continuously administering an appropriate amount of drug is desired.

[0008]

SUMMARY OF THE INVENTION It is an object of the present invention to provide a simple drug solution injector capable of continuously administering an appropriate amount of drug solution.

[0009]

SUMMARY OF THE INVENTION A drug solution injector according to the present invention is a drug solution reservoir arranged in a plane, a drug solution injector having a needle protruding vertically from the drug solution reservoir, and the drug solution reservoir. And a drug solution transfer means for transferring the drug solution to the drug solution injecting section.

In the present invention, the shape of the drug solution storage portion is not particularly limited as long as it can be arranged in a plane, and for example, a thin tube arranged in a spiral shape or a meandering shape is used.

In the present invention, it is preferable that the drug solution injecting section has two or more needles projecting vertically from the drug solution storage section and has an outer diameter of 0.25 mm or less. Further, it is preferable that a cushion layer is provided in a portion of the drug solution injector that is in contact with the injection target, and the needle is disposed in the cushion layer.

In the present invention, the means for transferring the drug solution stored in the drug solution storage part to the drug solution injecting part utilizes physical change or chemical change such as volume expansion, heat shrinkage, gas generating reaction, or A manual pump or a compressed gas tank that does not require a power source is preferable, but an electric pump or the like may be used.

[0013]

In the liquid injector according to the present invention, the needle is inserted vertically to the object to be injected, so that the position of the needle in the object to be injected is stable and the needle does not move even after a long time has passed. There is no slipping out. In addition, when the injected object is the body of the patient, if the outer diameter of the needle is 0.25 mm or less, the patient hardly feels pain not only when the needle is inserted but also when the needle is allowed to stay in the body for a long time. Therefore, it does not interfere with daily life.
Further, since the medicinal solution is directly injected subcutaneously from the needle, it is well absorbed into blood and the medicinal solution is physiologically efficient. Moreover, since the medicinal solution is continuously injected at a substantially constant flow rate from the needle protruding vertically from the medicinal solution storage unit, physical condition disorder due to temporary overdose does not occur. Furthermore, since the chemical injection device of the present invention can be used as a disposable item, contamination with bacteria is very small.

[0014]

Embodiments of the present invention will be described below with reference to the drawings.

Embodiment 1 FIG. 1 shows a first embodiment of the present invention. In this embodiment, the drug solution 1 is stored in a tubular drug solution storage unit 2 formed in a spiral shape, and one end of the drug solution storage unit 2 is equipped with three needles 3 having an outer diameter of 0.2 mm. There is 4. Further, the other end of the chemical liquid storage unit 2 is filled with the super absorbent material 5 and water 6. A spacer 7 is arranged between the chemical liquid 1 and the superabsorbent material 5 to separate them. Further, a stopper 8 having a through hole is provided between the chemical liquid storage unit 2 and the chemical liquid injection unit 4, and functions to prevent the spacer 7 from moving to the chemical liquid injection unit 4. Further, a manual release valve 9 is provided between the superabsorbent material 5 and the water 6. Similarly, a manual release valve 10 is provided at the end of the tube filled with water 6. FIG. 2 is a sectional view taken along the line AA ′ of FIG. A coating layer 11 is provided on the upper surface, and a separation layer 12 is provided on the lower surface thereof to separate adjacent tubes of the chemical liquid storage unit 2 from each other. In addition, the drug solution storage unit 2 and the separation layer 12
A cushion layer 13 is provided under the. A needle 3 is provided in the liquid medicine injection unit 4 provided in the central portion, and is connected to the liquid medicine 1 and the liquid medicine storage unit 2. An adhesive layer 14 is provided on the lower surfaces of the covering layer 11 and the cushion layer 13.

The details of each section will be described below.

First, the needle 3 will be described. The needle 3 projects in the vertical direction with respect to the drug solution storage unit 2 arranged in a plane. By thus providing the needle 3 in the direction perpendicular to the flow of the liquid in the liquid medicine storage unit 2, it is possible to continuously inject an appropriate amount of the liquid medicine without changing the flow rate. FIG. 3 shows the relationship between the installation direction of the needle and the flow rate at the tip of the needle with respect to the flow of the liquid. In this figure, a needle is attached to the tip of a tube filled with a drug solution, a needleless syringe is attached to the other end of the tube, a certain pressure is applied to the piston, and the flow rate of the drug solution at the needle tip at that time was measured. It is a thing. The flow rate is standardized with the flow rate when stable as 100. When a needle was provided at the tip of the tube in parallel with the length direction of the tube, although the initial rise was fast, the flow rate fluctuation thereafter was large and it took a long time to stabilize. Moreover, pulsation of the flow rate was observed even in the steady state.
On the other hand, when a needle was provided on the side surface of the tip of the tube in a direction perpendicular to the length direction of the tube, although the initial rise was slow, a constant flow rate was reached quickly and temporary excess outflow did not occur. Almost no fluctuation in flow rate was observed in the steady state. From this result, it was found that it is possible to continuously inject an appropriate amount of the drug solution without changing the flow rate by providing the needle 3 in the vertical direction with respect to the drug solution storage unit 2 provided in a plane. It was

It is desirable to provide a plurality of needles 3, and in this embodiment, three needles are provided around one end of the chemical liquid storage section 2. The material of the needle 3 is, for example, stainless steel (for example, S
US304 and SUS321), metals such as copper and copper alloys, aluminum and aluminum alloys, semiconductors such as silicon, and metal oxides such as silica are used. As a method of manufacturing the needle 3, a stretching method, a casting method, a wire discharge grinding method, or the like can be used. In the case of silicon, it is formed by using a photolithography technique such as etching. Further, the shape of the needle 3 does not necessarily have to be a cylindrical tube. Further, the needle 3 does not have to be hollow like an ordinary injection needle, and may be a needle without holes, for example, a needle made of a porous material or a needle having a groove on its side surface. .

FIG. 4 shows the relationship between the outer diameter of the needle and the pain during insertion. The horizontal axis represents the outer diameter of the needle, and the vertical axis represents the pain when the needle is inserted vertically into the arm, and the pain when the needle having the outer diameter of 0.7 mm is inserted is represented as 100. The insertion depth was 3 mm. From the results of FIG. 4, it was found that the pain at the time of inserting the needle is closely related to the outer diameter of the needle, and almost no pain can be felt with a needle having an outer diameter of 0.25 mm or less. Therefore,
The outer diameter of the needle 3 is preferably 0.25 mm or less.
FIG. 5 shows the cutting edge portion of the needle 3. The tip of the needle 3 is processed into an acute angle, and the angle θ is 20 ° or less. In order to reduce resistance and pain during insertion, it is more preferable that the angle be 15 ° or less. The ground surface of the cutting edge may be flat as shown in FIG. 5 or may be curved as shown in FIG. Further, as shown in FIG. 7, the ground surface of the cutting edge may have two or more surfaces having different angles. In addition, in order to reduce resistance and pain at the time of insertion, the ground surface of the cutting edge of the needle 3 and the side surface of the tube are ground so that the average surface roughness is 5 μm or less.

Next, the cross section of the needle 3 is shown in FIG. Needle tube 15
Inside, the core 16 is provided in close contact with or close to its inner wall. When the drug solution 1 is filled in the needle tube 15, the surface tension of the solution becomes a large resistance without the inner tube, and it is difficult to fill the needle tube 15 easily. However, since the narrow gap is formed between the outer wall of the core 16 and the inner wall of the needle tube 15 due to the presence of the core 16, the drug solution 1 can be easily filled in the needle tube 15 by the capillary phenomenon. The smaller the inner diameter of the needle tube 15, the greater the effect of the core 16. However,
If the inner diameter of the needle tube 15 is large to some extent, the core 16 can be omitted. Further, although the core 16 is a hollow tube in FIG. 8, the same effect can be obtained even if the core 16 is not hollow as shown in FIG.

FIG. 10 shows an enlarged view of the connecting portion between the proximal end portion of the needle 3 and the chemical liquid storage portion 2. An eaves is formed at the base end of the needle 3 and is fixed to the outer wall or lower layer of the drug solution storage unit 2. This eaves has the effect of firmly fixing the needle 3 against the resistance applied when the needle 3 is inserted into the living body or withdrawn. It is desirable from the standpoint of strength that a plurality of eaves at the base end portion are formed as shown in FIG.

As shown in FIG. 2, a cushion layer 13 is provided below the drug solution storage unit 2 and the drug solution injection unit 4, that is, on the side contacting the living body. Cushion layer 13
As the material, a material whose thickness is deformed by an external force, for example, a porous foamed resin such as polyurethane or polyethylene is used. In addition, it is desirable that the deformation in the thickness direction is irreversible from the viewpoint of stability after insertion of the needle. This cushion layer 13 is
After the chemical liquid injector according to the present invention is attached to a living body which is an object to be injected, when the needle 3 is inserted, it has a function of holding the needle 3 so that the needle 3 pierces the living body accurately in a vertical direction.
The cushion layer 13 enables the needle 3 to be inserted into the living body reliably and accurately without being bent or curved. Before use, that is, before attaching the drug solution injector according to the present invention to a living body, the needle 3 is accommodated in the cushion layer 13 more than half of its length in the longitudinal direction. In order to protect the tip of the needle and prevent the inside from being contaminated, it is desirable that the needle 3 is entirely housed in the cushion layer 13 as shown in FIG. Further, as shown in FIG. 13, when the external force is applied from above the needle 3 to insert the needle 3 into the living body 17,
The cushion layer 13 is thickness-deformed by the external force. An adhesive layer 14 is provided on the surface of the cushion layer 13 so that the needle insertion portion is fixed so as not to shift.

Next, the chemical liquid storage section 2 will be described. In the liquid medicine injection device shown in FIG. 1, the liquid medicine reservoir 2 is formed in a spiral pattern, but a curved pattern as shown in FIG. 14 may be used. The cross-sectional shape is preferably circular as shown in FIG. 2, but may be elliptical or quadrangular. The chemical liquid storage unit 2 is formed of a tube. As the material of the tube, a resin tube such as silicone or tetrafluoroethylene, or a metal tube is used. Further, instead of using the tube, the separation layer 12 may be processed to form a tubular groove, and the groove may be used as the chemical liquid storage section. For example, a method such as etching a silicon substrate is used.

A super-water-absorbing substance 5 and water 6 are filled in the end portion of the pipe of the chemical liquid storage section 2. The highly water-absorbent substance 5 and the water 6 have a function as a transfer unit that gradually pushes the liquid medicine 1 out of the needle 3. Super absorbent material 5 is water 6
When it comes into contact with it, it absorbs it internally and causes volume expansion. The chemical liquid 1 is transferred by the expansion force. As the superabsorbent material, for example, powder of superabsorbent polymer such as polyvinyl alcohol / sodium acrylate copolymer which causes volume expansion of several tens times or more is used. A manual release valve 9 is provided between the superabsorbent material 5 and the water 6.
The structure of the manual release valve 9 is shown in FIG. Inside the pipe of the chemical liquid storage unit 2, there is a thin separation film 18 for separating the superabsorbent material 5 and the water 6, and a projection 19 having a sharp tip is formed on the upper portion thereof. By applying an external force from the upper part of the protrusion 19, the protrusion 18 penetrates the separation membrane 19 and a through hole is formed. When the external force is released, the projections 19 return to the same arrangement as in FIG. 15, the water 6 enters the superabsorbent material 5, and the volume expansion of the superabsorbent material starts. It is desirable that the operation of applying the external force to form the through holes in the separation membrane 19 is performed before the chemical injection device is attached to the injection target. By the operation before the attachment, the air remaining inside the needle can be removed. On the other hand, as shown in FIG. 1, a similar manual release valve 10 is provided at the other end of the portion containing the water 6. The manual release valve 10 is formed between a room communicating with the atmosphere and water as shown in FIG. A hole is formed in the separation membrane 18 by a projection 19 and one end of the tube containing the water 6 is opened to the atmosphere, so that the water can be smoothly moved to a portion where the superabsorbent material 5 is present.

In the first embodiment, the volume expansion of the highly water-absorbing substance is used as the chemical liquid transfer portion, but any substance may be used as long as the volume expansion is gradually caused by heat or chemical reaction.

Between the liquid medicine 1 and the superabsorbent material 5 is shown in FIG.
The spacer 7 as shown in FIG. The spacer 7 separates the drug solution 1 and the superabsorbent substance 5 so as not to mix with each other, and moves in the pipe of the drug solution storage unit 2 in accordance with the volume expansion of the superabsorbent substance 5. The shape is preferably spherical or cylindrical as shown in FIG. The outer diameter thereof is the same as or slightly larger than the inner diameter of the tube of the chemical liquid storage unit 2. Further, in the drug solution storage unit 2 of FIG. 1, a stopper 8 is provided in front of the drug solution injection unit 4 provided with the needle 3 so that the spacer 7 does not move to the drug solution injection unit 4. The structure of the stopper 8 is shown in FIGS. 19 and 20. The stopper 8 has a shape in which the inner diameter of the pipe of the chemical liquid storage part 2 is partially narrowed.
FIG. 19 shows a state in which the spacer 7 that has moved is forcibly stopped by the stopper 8.
The side surface of the spacer 7 is formed so that its curvature matches the contact surface of the spacer 7. Further, the through hole at the center of the stopper 8 is formed concentrically with the pipe of the drug solution storage unit 2 as shown in FIG. By providing the stopper 8 as described above, the movement of the spacer 7 is blocked, and the superabsorbent substance 5 is prevented from being injected into the living body from the needle through the drug solution injecting section 4.

Next, the coating layer 11 will be described. Figure 2
A coating layer 11 is formed on the uppermost surface of the chemical liquid injector as shown in FIG. The coating layer 11 is preferably transparent or translucent so that the drug solution storage unit 2 existing therebelow can be seen through. In that case, it is preferable that the pipe of the chemical liquid storage unit 2 is also transparent or translucent and the spacer 7 is colored. As a result, it becomes possible to know the remaining amount of the chemical liquid 1 by looking at the position of the spacer 7 from the outside. More desirably, if the coating layer 11 is graduated along the pipe of the drug solution storage unit 2, the remaining amount of the drug solution 1 can be accurately observed. An adhesive layer 14 is formed on the coating layer 11 in the lower portion where the chemical liquid storage portion 2 or the separation layer 12 does not exist. This is for fixing the drug solution injector to the injection target, and at the same time when the needle 3 is inserted into the injection target, the adhesive layer 14 is adhered to the injection target and the cushion layer 13 is compressed. It has a function of fixing so as to be held in a state. Similarly, the adhesive layer 14 is provided on the lower surface of the cushion layer 13. However, the adhesive layer 14 of the coating layer 11
Alternatively, the adhesive layer 14 of the cushion layer 13 is not always necessary. When the surface condition of the injectable substance is poor and the adhesiveness is insufficient, or when there is a problem of allergy, the drug solution injector is attached to the injectable substance without providing the adhesive layer 14, and a bandage or You may fix using another fixing tool, such as a supporter.

To summarize the method of use of the first embodiment described above, first, the upper surface of the manual release valve 9 is pressed with a finger or the like to bring the superabsorbent material 5 and water 6 into contact with each other. Next, the upper surface of the manual release valve 10 is pushed with a finger or the like to bring one end of the tube containing the water 6 into the atmosphere open state. After confirming that the drug solution 1 has come out of the tip of the needle 3 as the volume of the superabsorbent material 5 is expanded, the drug solution 1 is attached to the surface of the injection target, for example, the living body. Further, the upper surface of the portion having the needle 3 is strongly pressed with a finger or the like, and at the same time or immediately thereafter, the entire surface of the chemical liquid injector is pressed to fix the adhesive layer 14 in close contact with the surface of the object to be injected. When a predetermined amount of the chemical liquid is injected or when the spacer 7 moves to the stopper 9, it is removed from the surface of the injection target and discarded.

Embodiment 2 FIG. 21 and FIG. 22 show a second embodiment in which the arrangement relationship between the chemical liquid storage unit and the chemical liquid transfer unit is different from that of the first embodiment. First
In the above-mentioned embodiment, the superabsorbent substance and water, which are the drug solution transfer parts, are arranged in the same pipe as the drug solution storage part, and the drug solution is pushed from the rear. On the other hand, in the embodiment shown in FIGS. 21 and 22, the highly water-absorbing substance 5 is provided around the tubular drug solution storage unit 2.
And water 6 are placed. FIG. 23 shows a cross-sectional view around the drug solution storage unit 2. The drug solution storage unit and the drug solution transfer unit have a double pipe structure, and the drug solution 1 is contained in the inner pipe 20
The super absorbent material 5 is provided between the outer tube 21 and the outer tube 21, and water 6 is filled around the outer tube 21. Also, the outer tube 21
Has a thin portion, and a projection 19 is provided on the upper portion thereof to form the manual release valve 9. By applying an external force from the upper surface of the projection 19, the projection 19 penetrates the thinned portion of the outer tube 21 to form a flow hole, and the water 6 permeates the superabsorbent material 5 to start volume expansion. The inner tube 20 is pressed by the volume expansion of the highly water-absorbent substance 5, and the chemical liquid 1 inside
Are transferred. It is desirable that the hardness of the outer tube 21 is larger than that of the inner tube 20 from the viewpoint of the transfer efficiency of the drug solution 1. In this embodiment, the spacers and stoppers used in the first embodiment are not required at all, and there is no risk of the superabsorbent substance 5 being mixed into the chemical liquid 1.

The chemical liquid transfer section may be a material that gradually expands in volume due to heat or a chemical reaction, in addition to the combination of the superabsorbent material and water. The arrangement of the drug solution transfer unit 22 with respect to the drug solution storage unit 2 may be such that the pipe 21 of the drug solution storage unit is entirely surrounded by the drug solution transfer unit 22 containing a substance that causes volume expansion as shown in FIG. It is also possible to adopt a structure in which the planar liquid medicine transfer unit 22 as shown is arranged above or below the liquid medicine storage unit 2. Further, in the case of such a planar chemical liquid transfer unit 20, the structure of the chemical liquid storage unit 2 does not need to be tubular, and may be a planar shape. In this planar drug solution storage unit 2, a plurality of needles 3
It is desirable to disperse all of them instead of concentrating them in one place.

Embodiment 3 FIG. 26 shows a third embodiment in which compressed air by a manual pump is used as the chemical liquid transfer section. A compressed air tank 23 and a manual pump 24 are connected to an end of the chemical liquid storage unit 2 opposite to the chemical liquid injection unit 4. A check valve 25 is provided between the compressed air tank 23 and the manual pump 24,
It functions so that the air sent from the manual pump does not flow back from the compressed air tank 23. Further, the manual pump 24 has a suction hole 26 communicating with the atmosphere, and a check valve 25 is also provided there. Further, the compressed air tank has a leak valve 27 that releases air when the internal pressure exceeds a predetermined pressure.
Is attached. A pressure adjusting valve 28 is provided between the compressed air tank 23 and the chemical liquid storage unit 2 so as to press the spacer 7 at a constant pressure. FIG. 27 shows C- of FIG.
It is a sectional view taken along the line C '. Manual pump 2
When an external force is applied from the upper part of 4, the volume of the inner chamber 29 is reduced and the air in the inner chamber 29 is sent to the compressed air tank 23. Then, when the external force is released, the volume of the inner chamber 29 tries to return to the original volume, and the air is sucked from the outside through the suction hole 26. The compressed air thus stored in the compressed air tank 23 transfers the chemical liquid through the spacer 7. The timing of pushing the manual pump may be such that the operation is performed several times intermittently, and the transfer speed of the chemical liquid is kept substantially constant by the pressure adjusting valve 28 without depending on the pressure in the compressed air tank 23. Further, the compressed air tank 23 can be omitted.

Similarly, FIG. 28 shows another embodiment in which the pressure of the compressed gas is used as the chemical liquid transfer section. A plurality of compressed gas tanks 3 are provided at the end of the chemical liquid storage unit 2 opposite to the chemical liquid injection unit 4.
It is connected to 0. Each compressed gas tank 30 is equipped with a manual release valve 9 and a check valve 25. The manual release valves 9 of the respective compressed gas tanks 30 are opened one after another in order. The check valve 25 functions to prevent the gas from flowing into the already released compressed gas tank when the compressed gas tank is newly opened. The gas pressure of each compressed gas tank 30 is set higher in the order of releasing the compressed gas tank 30 later, and together with the function of the pressure adjusting valve 28, the chemical liquid can be transferred at a constant pressure.

Further, the chemical liquid transfer section utilizing the gas pressure in this embodiment has a structure in which the chemical liquid 1 in the tubular chemical liquid storage unit 2 is pushed from the end through the spacer 7, but it is different from the second embodiment. Similarly, a chamber of compressed gas may be arranged around the tubular drug solution storage unit 2. Further, in this case, the drug solution storage unit 2 does not have to be tubular, and may have a planar shape.

Fourth Embodiment A fourth embodiment in which the chemical liquid storage section 2 also serves as the chemical liquid transfer section will be described. FIG. 29 shows a cross section of the tubular drug solution storage unit 2. The pipe 31 of the chemical liquid storage part is made of a heat-shrinkable material, and a heat conducting layer 32 is formed around the pipe. The heat conduction layer 32 is also formed on the outermost top surface, and the heat conduction layer 32 around the pipe 31 of the chemical liquid storage section is formed.
Connected with. By bringing a heating element such as an electric heater or a disposable body warmer into contact with the heat conduction layer 32 on the outer surface, the heat is transferred through the heat conduction layer 32 to the pipe 3 of the chemical solution storage unit.
1, the tube 31 contracts and its diameter decreases. Due to the change in the shape of the pipe 31, the internal chemical solution 1 is transferred. As the heat-shrinkable substance of the tube 31, heat-shrinkable rubber such as silicon resin or fluororesin is used. Also, the pipe 31
Is not limited to a heat-shrinkable substance, but a shape memory substance that deforms in shape depending on temperature can be used. A metal thin film such as copper is used for the heat conduction layer 32. To prevent the deterioration of the drug solution,
It is desirable that a heat insulating layer is provided on the inner wall of the pipe 31 of the chemical liquid storage section so that heat cannot be easily transferred to the chemical liquid. Also, the separation layer 1
It is preferable to use a material having a low thermal conductivity for the material 2. Further, it is desirable from the viewpoint of transfer efficiency of the drug solution that the heating element to be brought into contact with the heat conduction layer 32 on the outer surface is provided in the vicinity of the upper surface of the tubular drug solution storage unit 2 opposite to the drug solution injection unit side. As another heating method, a structure in which the heat conduction layer 32 is provided on the contact surface side with the living body and the tube 31 is contracted by using the body temperature as a heat source may be used.

Embodiment 5 FIG. 30 shows a fifth embodiment having a structure in which the drug solution storage unit 2 and the drug solution injection unit 4 and the drug solution transfer unit 37 are separated. The chemical liquid transfer unit 37 includes a pump 33, a drive circuit 34, and a power source 35, and is connected to the chemical liquid storage unit 2 by a tube 36. In this case, the drug solution transfer unit 37 does not need to be disposable, and only the drug solution storage unit 2 and the drug solution injection unit 4 need to be disposable, so that the use cost is low.

Example 6 In this example, an apparatus for continuously injecting a medicinal solution into a plant will be described. FIG. 31 shows an apparatus 51 of this embodiment. In FIG. 31, inside a planar device main body 52 made of a polymer material such as polypropylene, silicone, or polyimide, a drug solution storage part 53, a drug solution retention part 54, and a pump mechanism part 55, which are separated from each other by partition walls, are provided. A needle 56 for injecting a drug solution is fixed to the drug solution retention portion 54. The drug solution storage unit 53 contains a drug solution 57 for healing plant diseases. The pump mechanism unit 55 can be of any type such as mechanical type or electric type, but the type that pumps the chemical liquid to the chemical liquid storage unit 53 by its pressure is convenient. is there.

As shown in FIG. 32, a protrusion 59 is provided in the vicinity of the partition wall 58 between the chemical liquid retention portion 54 and the chemical liquid storage portion 53 (and between the chemical liquid storage portion 53 and the pump mechanism portion 55). There is. When the partition wall 58 is opened by pushing it from above during use, the chemical solution is pushed out to the chemical solution storage section 53 and then to the chemical solution retention section 54 by the pressure of the gas generated inside the pump mechanism section 55, and further passed through the needle 56. Injected into plants.

The needle is preferably thin in order to reduce damage to plants, and is preferably about 50 μm to several mm. As the material of the needle, a metal such as stainless steel or aluminum, or a semiconductor such as silicon may be used. The needle does not necessarily have to be hollow, and may be porous with small holes throughout the needle. When a porous needle is used, unlike the case of a hollow needle, the drug solution does not vigorously come out, and the drug solution seeps out, which is more suitable for continuously injecting the drug solution. The porous needle can be easily formed by using silicon, which is a semiconductor material, and it is easier to form a needle having a smaller diameter than other materials. Moreover, the cost can be reduced by mass production.

As shown in FIG. 33, the device 51 of the present embodiment.
Is fixed on the surface of the stem 60 of the plant. At this time, since the needle 56 sticks into the plant stem 60, the needle 60 can be fixed by itself, but it is preferable to use a reinforcing means such as sticking a double-sided tape on the lower surface of the device 51 or fixing the adhesive tape from above. Since the needle 56 is thin, it does not adversely affect the plants.

When the apparatus of this embodiment is used, the medicinal solution is directly injected into the plant, so that the effect can be obtained quickly and the medicinal solution can be used in the minimum amount, so that there is no waste. Further, a greater effect can be obtained as compared with the method of spraying the drug on the root, and the contamination with the chemical liquid other than the target plant can be suppressed. Furthermore, since the drug solution can be continuously injected into the plant, the effect is highly durable.

It is also possible to use a dye as the liquid medicine. For example, a method of injecting a liquid containing a red dye into a plant having white flowers to make the petals red or changing the color of a part of the leaves is also considered. To be In addition, a fragrance can be used as a liquid medicine, and a method of utilizing the fragrance of a flower having a weak fragrance can be considered.

Example 7 A mite-proofing agent injecting device for tatami mats will be described with reference to FIG.
As shown in FIG. 34 (a), the device 70 of this embodiment has about 3
A large number of hollow stainless steel needles 72 are vertically projected on the surface of a substrate 71 made of high-strength plastic such as 0 cm square and about 5 mm thick, such as hard vinyl chloride and polypropylene. Needle thickness is 1-2 mm, length is 5-3
It is 0 mm. As shown in FIG. 34B, this substrate 71
Grooves 72 are formed in a meandering manner inside, and the anti-mitic agent is stored inside thereof. The needles are previously embedded so as to correspond to the grooves when the sheet is cast. The reason why the lengths of the needles are made nonuniform as described above is to three-dimensionally make uniform the injection amount of the anti-mitic agent inside the tatami mat. When the needle is not in use, the tip of the needle is protected with urethane foam, etc., to prevent leakage and drying of the anti-mite agent. This device is not provided with any special means for transferring the anti-tick agent, but this does not allow the anti-tick agent to be pressed by pressing the device with the weight of the tatami mat and the weight of the person walking on the tatami mat. This is because it is injected into the tatami mat. As shown in FIG. 35, this device 70 is used by laying it on the back surface of a tatami mat 73. Therefore, it is not necessary to attach an adhesive to the substrate surface. By using this device, the mites-preventing effect can be maintained for about 2 years. It is more effective to embed this device in advance between the back side of the tatami mat and the tatami mat.

Embodiment 8 A fungicide injection device for air conditioner filters will be described with reference to FIG. The device 80 of this embodiment has a thickness of 5 mm,
A polypropylene resin having a height of 2 cm and a width corresponding to the width of the filter is filled with a fungicide in a chemical solution storage portion 81 having a groove of 3 mm × 1.5 cm formed therein, and a thickness of 1 mm and a length of 1 c.
A large number of hollow stainless steel needles 82 having a diameter of m are embedded, an air chamber 83 is formed in an upper portion of the needle 82, and an electric pump 84 communicating with an end of the air chamber 83 via a valve (not shown) is provided. The device 80 is installed on the filter 86 of the air conditioner 85. Air is pushed out from the electric pump 84 into the air chamber 83, a certain pressure is applied to the chemical liquid storage portion, the antifungal agent is supplied to the filter 86 through the needle 82, and the antifungal agent gradually permeates to the lower part of the filter 86. Reach up to. The electric pump 84 is controlled by a timer so that when the air conditioner is not used, the antifungal agent is operated for a certain period of time to reach the bottom of the filter. This is to suppress the amount of the fungicide released from the air outlet of the air conditioner as much as possible and to maintain its effect. By using this device, the antifungal effect can be maintained only by changing the antifungal agent once a year.

Example 9 A fungicide injection device for wallpaper will be described with reference to FIG.
As shown in FIG. 37 (a), this device 90 has a thickness of 0.1 to 0.2 m on one side of an adhesive tape 91 impregnated with a mildew proofing agent.
The microscopic needles 92 made of non-hollow aluminum having a length of m and a length of about 0.5 mm (about 1/2 of the thickness of the wallpaper) are densely packed. As shown in FIG. 37 (b), this device 90 has a wallpaper 9
It is provided so as to be in close contact with the back surface of 3. In this way, the mildew-proofing agent can be made to penetrate into the vicinity of the surface of the wallpaper 93, and the mildew-proofing effect can be maintained for a period of 1.5 times or more of the conventional period.

Example 10 An insect repellent injection device for wooden products will be described with reference to FIG. As shown in FIG. 38, this device 100 functions as a screw, and the head of the screw is hollow to form a chemical solution storage portion 101, which is filled with a termite insecticide, and the upper end of the screw groove is minutely filled. The hole 102 is provided. The size of the head, the thickness of the screw portion, the pitch width, etc. are variously selected according to the desired duration of the chemical solution effect, the place of use (object), and the like. Before use, the micropores 102 are blocked with a plug, tape, or the like, so that leakage of the chemical solution does not occur. This device 100 is used by screwing it into a wooden product 103 such as a pillar. Then, the chemical solution gradually leaks from the minute holes 102, flows down along the screw groove, and permeates a wide range inside the wooden product. Since the device of this embodiment is not provided with a special chemical liquid transfer means, the device is installed and fixed along the direction of gravity (not necessarily in the vertical direction).

[0046]

As described above, in the device of the present invention,
It is possible to continuously inject an appropriate amount of drug solution.

[Brief description of drawings]

FIG. 1 is a plan view of a chemical liquid injector according to a first embodiment of the present invention.

FIG. 2 is a sectional view taken along the line AA ′ of FIG.

FIG. 3 is a diagram showing a change over time in the flow rate of the chemical liquid due to a difference in the arrangement direction of the needle with respect to the chemical liquid storage unit.

FIG. 4 is a diagram showing the relationship between the outer diameter of the needle and pain during insertion.

FIG. 5 is a view showing the tip shape of a needle provided in the drug solution injector of FIG.

FIG. 6 is a view showing the tip shape of another needle provided in the chemical liquid injector of FIG.

FIG. 7 is a view showing the tip shape of yet another needle provided in the chemical liquid injector of FIG.

8 is a cross-sectional view of a needle provided in the drug solution injector of FIG.

9 is a cross-sectional view of another needle provided in the drug solution injector of FIG.

10 is a view showing the structure of the base end portion of the needle provided in the liquid medicine injection portion of FIG.

FIG. 11 is a view showing a structure of a base end portion of another needle provided in the chemical liquid injection portion of FIG.

FIG. 12 is a view showing the arrangement of needles before attaching the drug solution injector of FIG. 1 to a living body.

FIG. 13 is a view showing the arrangement of needles after the chemical injection device of FIG. 1 is attached to a living body.

FIG. 14 is a plan view of a chemical liquid injector according to another embodiment in which the shape of the chemical liquid storage section is different from that of FIG.

15 is a cross-sectional view of the manual release valve provided between the superabsorbent material and water of FIG.

16 is a cross-sectional view of a manual release valve provided at the end of the water filled tube section of FIG.

17 is a cross-sectional view around the spacer of FIG.

FIG. 18 is a cross-sectional view around a spacer having a shape different from that in FIG.

19 is a cross-sectional view parallel to the moving direction of the spacer when the spacer reaches the stopper of FIG.

20 is a cross-sectional view perpendicular to the moving direction of the spacer when the spacer reaches the stopper of FIG.

FIG. 21 is a plan view of the chemical liquid injector according to the second embodiment of the present invention.

22 is a cross-sectional view taken along the line BB ′ of FIG.

FIG. 23 is an enlarged cross-sectional view showing the chemical liquid storage unit and the chemical liquid transfer unit of FIG. 21.

24 is an enlarged cross-sectional view showing a chemical liquid storage unit and a chemical liquid transfer unit different from those in FIG. 23.

FIG. 25 is an enlarged cross-sectional view showing a chemical liquid storage unit and a chemical liquid transfer unit which are different from those in FIG. 23.

FIG. 26 is a plan view of the chemical liquid injector according to the third embodiment of the present invention.

27 is a cross-sectional view taken along the line CC ′ of FIG.

FIG. 28 is a plan view of another chemical liquid injector having a different chemical liquid transfer section in the third embodiment.

FIG. 29 is a cross-sectional view of the periphery of the drug solution storage unit of the drug solution injector according to the fourth embodiment of the present invention.

FIG. 30 is a plan view of the chemical liquid injector according to the embodiment of the present invention.

FIG. 31 is a sectional view of a chemical injection device according to a sixth embodiment of the present invention.

FIG. 32 is an enlarged sectional view showing a part of the chemical liquid injector according to the sixth embodiment of the present invention.

FIG. 33 is a view showing a method of using the chemical liquid injector according to the sixth embodiment of the present invention.

FIG. 34 is a perspective view showing the configuration of a mite-proofing agent injection device for tatami mats according to Example 7 of the present invention.

FIG. 35 is a view showing a method of using the tick-proofing agent injection device for tatami mats according to Example 7 of the present invention.

FIG. 36 is a view showing a method of using the antifungal agent injection device for a filter of an air conditioner according to Example 8 of the present invention.

FIG. 37 is a diagram showing the configuration and method of using the antifungal agent injection device for wallpaper in Example 9 of the present invention.

FIG. 38 is a view showing a method of using the insect repellent injection device for wooden products in Embodiment 10 of the present invention.

[Explanation of symbols]

1 ... Medicinal solution, 2 ... Medicinal solution storage section, 3 ... Needle, 4 ... Medicinal solution injection section,
5 ... Super absorbent material, 6 ... Water, 7 ... Spacer, 8 ... Stopper, 9, 10 ... Manual release valve, 11 ... Coating layer, 12 ...
Separation layer, 13 ... Cushion layer, 14 ... Adhesive layer, 15 ... Needle tube, 16 ... Core, 17 ... Living body, 18 ... Separation membrane, 19 ... Projection, 20 ... Inner tube, 21 ... Outer tube, 22 ... Chemical liquid transfer section, 23
… Compressed air tank, 24… Manual pump, 25… Check valve,
26 ... Suction hole, 27 ... Leak valve, 28 ... Pressure adjusting valve, 2
9 ... Inner chamber of manual pump, 30 ... Compressed gas tank, 31 ...
Heat-shrinkable tube, 32 ... Heat conductive layer, 33 ... Pump, 34 ... Drive circuit, 35 ... Power supply, 36 ... Tube, 37 ... Chemical solution transfer section, 51 ... Chemical solution injection device, 52 ... Device body, 53 ... Chemical solution storage section , 54 ... Chemical solution retention part, 55 ... Pump mechanism part, 56
... needle, 57 ... chemical solution, 58 ... partition wall, 59 ... protrusion, 60 ... plant stem, 70 ... chemical solution injection device, 71 ... substrate, 72 ... needle,
73 ... Groove, 74 ... Tatami, 80 ... Chemical liquid injection device, 81 ... Chemical liquid storage part, 82 ... Needle, 83 ... Air chamber, 84 ... Electric pump, 85 ... Air conditioner, 86 ... Filter, 90 ... Chemical liquid injection device, 91 … Adhesive tape, 92… Needles, 93… Wallpaper, 1
00 ... Chemical liquid injection device, 101 ... Chemical liquid storage unit, 102 ... Micropores, 103 ... Wooden products.

Claims (1)

[Claims] 1. A drug solution storage unit arranged in a plane, a drug solution injection unit having a needle protruding vertically from the drug solution storage unit, and a drug solution transfer for transferring the drug solution in the drug solution storage unit to the drug solution injection unit. A liquid medicine injection device comprising: