CN211486218U - Device capable of continuously covering and injecting liquid medicine - Google Patents

Abstract

The utility model relates to a sustainable cover device of pouring into liquid medicine, including pipeline and a plurality of hollow micropins, the pipeline is equipped with pipeline play medicine mouth, pipeline and advances the medicine mouth, and the micropins distributes at the lower extreme of pipeline, advances medicine end and pipeline intercommunication. By arranging the pipeline communicated with the hollow microneedle, the liquid medicine can be uniformly injected into the hollow microneedle through the pipeline, the liquid medicine is more flexible to use, the liquid medicine is also suitable for being replaced according to different treatment stages, the liquid medicine can be used for multiple times, the microneedle application is not required to be frequently replaced, the waste of the liquid medicine is reduced, and the treatment cost is saved; and the micro-needle penetrates into the epidermis, so that the treatment effect is better.

Description

Device capable of continuously covering and injecting liquid medicine

Technical Field

The utility model relates to a medical device, in particular to a device capable of continuously covering injection liquid medicine.

Background

The statements in this section merely provide background information related to the present disclosure and may constitute prior art. In implementing the present invention, the inventors found that there are at least the following problems in the prior art.

Many diseases requiring continuous and covering treatment on the affected part, such as hemangioma and the like, generally adopt a mode of continuously dropping liquid medicine on the affected part directly, thereby wasting liquid medicine and having poor treatment effect; part of the medicine is applied in a mode of applying, so that the medicine can be continuously soaked in the affected part. However, this method can only be performed on the skin surface, and cannot be directly applied to the epidermis, and the effect is limited.

Recently, there are methods of treating affected parts by using microneedle arrays, for example, in the patent application No. 201910029211.0 entitled "microneedle transdermal patch for treating rheumatoid arthritis and method for preparing the same", or in the patent application No. 201820741785.1 entitled "painless dissolvable vaccine microneedle patch", all of which use microneedles arranged to cover and penetrate into the epidermis to treat affected parts or parts to be treated. The skin is only deeply penetrated into the epidermis, and the dermis is not damaged, so that the patient does not feel pain, and even if the pain is caused, the pain is slight. However, the liquid medicine can directly act on the subcutaneous part just because the liquid medicine penetrates into the epidermis, and has more direct effect compared with the application and dressing on the skin. And the microneedle technology also has good covering treatment effect, and can slowly release the liquid medicine to continuously treat the affected part. Microneedle therapy also has some problems. As can be seen from the above two patents, the method of embedding a drug in a microneedle is currently used, which can only embed one drug, and is disposable, very inflexible, especially not suitable for some diseases requiring frequent drug infusion, and also causes great waste. Most of the microneedles are arranged at standard equal intervals, and liquid medicine in the microneedles is in a basically circular treatment radiation range under the skin, so that the liquid medicine permeates into a wound surface unevenly, and the liquid medicine is covered repeatedly. And the microneedles are too dense, so that the treatment area is not convenient to observe, and a subsequent treatment scheme cannot be formulated or replaced.

Disclosure of Invention

In view of the above, it is an object of the present invention to solve some of the problems of the prior art, or at least alleviate them.

A device for continuously covering and injecting liquid medicine comprises

The pipeline comprises a pipe body, a pipeline medicine outlet and a pipeline medicine inlet;

a plurality of hollow microneedles distributed at a lower end of the tube; the drug inlet end of the microneedle is communicated with the pipeline.

The device capable of continuously covering and injecting the liquid medicine further comprises a sealing layer, wherein the sealing layer is located at the medicine outlet end of the micro needle and used for sealing the medicine outlet end of the micro needle.

Optionally, the pipeline is a pre-negative pressure vacuum pipe, a sealing film is arranged at the medicine inlet of the pipeline, and the medicine outlet of the pipeline is closed.

The device capable of continuously covering and injecting the liquid medicine also comprises an extrusion device which partially or completely wraps the pipeline; the pipeline is partially or completely a hose.

Furthermore, a needle base used for supporting the micro-needle is arranged between the drug inlet end of the micro-needle and the pipeline.

Optionally, the tube comprises an upper hose portion and a lower hard tube portion, and the drug inlet end of the microneedle is communicated with the lower hard tube portion.

The extrusion device comprises a closed cavity and a negative pressure compression piece; the negative pressure compression piece is made of compressible materials, is positioned in the closed cavity and wraps the pipeline; the closed cavity is provided with an extrusion device connecting port for connecting a negative pressure device; or the closed cavity is connected with an air duct for connecting a negative pressure device.

Furthermore, the negative pressure compression piece wraps the peripheral pipeline, and the closed cavity is a transparent cavity.

The microneedles are arranged at a preset angle and a preset interval.

The pipeline medicine outlet is provided with a color development device.

The utility model discloses following beneficial effect has:

1. the pipeline communicated with the hollow microneedle is arranged, so that the liquid medicine can be uniformly injected into the hollow microneedle through the pipeline, compared with a microneedle liquid medicine embedding technology, the liquid medicine is more flexible to use, is also suitable for replacing the liquid medicine according to different treatment stages, can be used for multiple times, does not need to frequently replace a microneedle patch, reduces the waste of the liquid medicine, and saves the treatment cost; the microneedle penetrates into the epidermis, so that the treatment effect is better;

2. the pipeline adopts a pre-negative pressure vacuum tube, so that the injection of the liquid medicine is more convenient, the liquid medicine can be filled in the pipeline only by inserting the mouth of the liquid medicine bottle into the sealing film of the medicine inlet of the pipeline and the negative pressure is realized, so that the operation of injecting the micro-needle with the liquid medicine is completed;

3. the extrusion device partially or completely wrapping the pipeline is arranged, so that the liquid medicine can smoothly enter the microneedle from the pipeline and can be injected into a treatment part;

4. the pipeline adopts a mode of combining the lower hard pipe part with the upper soft pipe part, or a needle base is arranged between the micro-needle and the pipeline, so that the problem that the micro-needle cannot exert force on the pipeline because the pipeline completely adopts the soft pipe is avoided, and the micro-needle can more easily penetrate into the skin;

5. the back-shaped or spiral pipeline is adopted, the negative pressure compression part of the extrusion device partially wraps the peripheral pipeline, the closed cavity adopts a transparent cavity body and is matched with a scheme of micro-needles which are communicated with the pipeline at a preset angle and a preset distance, so that the extrusion device can effectively apply pressure to the pipeline, and the treatment part can be conveniently observed, so that the next-stage dressing change or the treatment scheme change can be conveniently carried out;

6. compared with the micro-needles in the prior art, the micro-needles are arranged at preset angles and preset intervals and communicated with the pipeline, the coverage range of the micro-needles injected with liquid medicine is reduced, the utilization rate of the micro-needles is improved, the quantity of the micro-needles is effectively reduced, the cost of the device is reduced, the micro-needles are not so dense, and the treated part can be observed more conveniently.

Drawings

The above structure of the present invention can be further explained by the non-limiting examples given in the following figures.

FIG. 1 is a schematic view of one embodiment of an application layer of the present invention;

FIG. 2 is a schematic view of the present invention;

fig. 3 is a cross-sectional view of the present invention;

fig. 4 is a schematic view of one embodiment of a microneedle array according to the present invention;

fig. 5 is a schematic view of yet another embodiment of a microneedle arrangement according to the present invention;

FIG. 6 is a sectional view of the hose of the present invention;

FIG. 7 is a cross-sectional view of the present invention with the tube being a full hose;

fig. 8 is a diagram illustrating the effect of covering a treatment region with liquid medicine according to still another embodiment of the microneedle array of the present invention.

Wherein: 1-an extrusion device; 2-a medicine storage pool; 3-a pipeline; 4-opening; 5-a sealing layer; 6-microneedles; 7-a closed cavity; 8-pipeline medicine inlet; 9-a sticker; 10-extrusion device connection port; 11-pipeline medicine outlet; 12-drug-feeding end; 13-medicine discharging end; 14-a negative pressure compression member; 15-gas-guide tube; 16-an upper hose portion; 17-lower hard tube portion; 18-needle base.

Detailed Description

The following description of the present invention will be further described with reference to the accompanying drawings, and the embodiments of the present invention are only used for illustrating the present invention and not for limiting the present invention, and various replacements and modifications can be made according to the common technical knowledge and the conventional means in the field without departing from the technical idea of the present invention, and all should be included in the scope of the present invention.

As shown in fig. 1, a device for continuously covering and injecting a liquid medicine comprises

The pipeline 3 comprises a pipe body, a pipeline medicine outlet 11 and a pipeline medicine inlet 8;

a plurality of hollow microneedles 6 distributed at the lower end of the tube 3; the drug inlet end 12 of the microneedle 6 is communicated with the pipeline 3; the microneedles 6 are used to penetrate into the epidermis of the human body.

During the use, only need press this application device on treating the skin at position, micropin 6 gos deep into the epidermis, advances medicine liquid to pipeline medicine inlet 8 again to can be through setting up pipeline 3 with hollow micropin 6 intercommunication, make the liquid medicine can pour into in the hollow micropin 6 through pipeline 3. Compared with the microneedle embedded liquid medicine technology, the liquid medicine is more flexible to use, is also suitable for replacing the liquid medicine according to different treatment stages, can be used for multiple times, saves treatment cost, reduces waste of the liquid medicine, and improves the utilization rate. Finally, the device of the present application is applied to the skin by means of an adhesive means 9 such as tape, as shown in fig. 2, which is very convenient. The adhesive member 9 may also be attached to the device of the present application.

The micro-needle 6 is a micro-needle in the prior art, has small diameter and moderate length, can only penetrate into the epidermis without damaging dermal tissues, and thus can not bring pain to patients or cause slight pain. Since the microneedles 6 are relatively thin, there may be a case where less drug solution penetrates into the microneedles 6. After the tube 3 is filled with the liquid medicine, the tube outlet 11 can be blocked, and the pressure in the tube 3 is increased through the tube inlet 8 by an empty needle or the like, so that the liquid medicine in the tube 3 is forced to flow into the microneedle 6 and finally to the part to be treated. The pipeline medicine outlet 11 can be automatically plugged by hands or objects, and a sealing cover can be arranged on the pipeline medicine outlet 11 and covered when plugging is needed.

As the treatment part needs to be covered, the pipeline 3 can adopt a pipeline form with large covering area, such as a zigzag shape or a spiral shape, and the micro-needle 6 distributed at the lower end of the pipeline 3 can be matched to well carry out the covering injection treatment of the liquid medicine on the treatment part. The microneedles 6 may also be evenly distributed so as to cover the treatment site as much as possible. Of course, the shape of the conduit can be selected to suit a particular condition or treatment site according to actual needs.

The medicine storage pool 2 can be communicated with the pipeline medicine inlet 8 to add medicine liquid into the pipeline medicine inlet 8, as shown in fig. 2 or 3, an opening 4 and a cover for sealing the opening 4 are arranged at the upper part of the medicine storage pool 2, and the medicine liquid can flow into the medicine storage pool 2 to fill the pipeline 3 and the microneedle 6.

Also can use negative pressure device, go out 11 departments of medicine mouth at the pipeline and carry out the negative pressure operation to pipeline 3 to with the liquid medicine from medicine storage tank 2 or other medicine storage device, like eye medicine bottle etc. inhale to pipeline play medicine mouth 11, make the liquid medicine full of pipeline 3 and micropin 6, thereby help the liquid medicine can flow in smoothly and be full of pipeline 3 and micropin 6, avoid producing the problem that the liquid medicine can not be fine to get into because of pipeline 3 and the micropin 6 is thin.

The negative pressure device can be a negative pressure ball or an empty needle, and the negative pressure ball is pressed or a push rod of the empty needle is pulled, so that the pipeline 3 generates negative pressure, and the liquid medicine flows to the medicine outlet 11 of the pipeline. A special electric negative pressure device can be adopted to continuously and slowly pump pressure.

The method of injecting the liquid medicine into the medicine inlet 8 of the tube by an external force, such as pushing a syringe or squeezing a soft liquid medicine bottle, such as an eye drop bottle, may be employed to fill the tube 3 and the microneedles 6 with the liquid medicine, thereby helping the liquid medicine to smoothly flow into and fill the tube 3 and the microneedles 6. By adopting the method, only the medicine injection operation is needed to be carried out on the pipeline medicine inlet 8, and the operation on the pipeline medicine inlet 8 and the pipeline medicine outlet 11 is not needed, so that the operation is simpler and more convenient.

The device capable of continuously covering and injecting the liquid medicine further comprises a sealing layer 5, which is located at the medicine outlet end 13 of the microneedle 6 and is used for sealing the medicine outlet end 13 of the microneedle 6, as shown in fig. 2. Normally located below the drug outlet end 13 of the microneedle 6. When the device of this application is used to needs, can advance the liquid medicine through the pipeline into medicine mouth 8 injection pipeline 3 earlier, owing to there is closing layer 5 to seal the play medicine end 13 of micropin 6, just can flow out from pipeline play medicine mouth 11 after pipeline 3 and micropin 6 are filled with gradually to the liquid medicine. After the pipeline 3 and the micro-needle 6 are filled with the liquid medicine, the sealing layer 5 is torn off, and the device is pressed on the skin of the treatment area, so that the micro-needle 6 can carry the liquid medicine to go deep into the epidermis for treatment. The sealing layer 5 is adopted to seal the drug outlet end 13 of the microneedle 6 in advance, so that the microneedle 6 does not need to be pricked into the epidermis firstly and then the liquid medicine is injected into the pipeline 3 and the microneedle 6 through external force, the damage to the skin caused by the microneedle 6 which possibly penetrates into the epidermis due to the external force is avoided, and the micro-needle type drug delivery device is particularly suitable for patients with fragile skin such as infants.

Optionally, the pipeline 3 is a pre-negative pressure vacuum pipe, the pipeline medicine inlet 8 is provided with a sealing film, and the pipeline medicine outlet 11 is closed. The pipeline 3 adopts a pre-negative pressure vacuum tube, so that the injection of the liquid medicine is more convenient, the liquid medicine can be filled in the pipeline 3 by the negative pressure only by inserting a liquid medicine bottle mouth or a needle tube mouth into a sealing film of the medicine inlet 8 of the pipeline, and the treatment operation is more simple and convenient. The sealing layer 5 is torn off and the device of the present application is pressed against the treatment site. The tearing of the sealing layer 5 and the pressing of the device of the present application on the skin can also be performed simultaneously.

As shown in fig. 2 or 3, the device for continuously covering and injecting the liquid medicine further comprises an extrusion device 1 which partially or completely wraps the pipeline 3; the pipeline 3 is partially or completely a hose. After the pipeline 3 is filled with the liquid medicine, the pipeline medicine outlet 11 and the pipeline medicine inlet 8 are closed, the extrusion device 1 extrudes the hose part of the pipeline 3 through external force, so that the hose is collapsed by the external force, the volume in the pipeline 3 is reduced, the liquid medicine is forced to flow into the micro-needle 6, and the micro-needle 6 is ensured to be filled with the liquid medicine. The pipeline medicine outlet 11 and the pipeline medicine inlet 8 can be provided with sealing parts, such as sealing covers and the like, so that the sealing parts are convenient to seal and can be directly sealed by hands, and liquid medicine is prevented from being extruded from ports at two sides. Through setting up extrusion device 1 of part or whole parcel pipeline 3, make external negative pressure extrusion hose portion, guarantee that liquid medicine pressurized in the pipeline 3 can flow into micropin 6 smoothly, avoid because of pipeline 3 and micropin 6 are tiny, the liquid medicine flows to pipeline play medicine mouth 11 back from pipeline medicine inlet 8, and the difficult infiltration of liquid medicine micropin 6 or infiltration are few, influence treatment. Meanwhile, the liquid medicine can be uniformly injected into all the microneedles 6.

Meanwhile, the extrusion device 1 is also beneficial to extruding the liquid medicine in the micro-needle 6 to the treatment part. The pipeline 3 is extruded by external force, so that the liquid medicine cannot easily flow into a treatment part because the micro-needle 6 is too small, and the treatment effect is not influenced. The specific operation is as follows: after the pipeline 3 is filled with the liquid medicine, the liquid medicine in the pipeline 3 is extruded into the micro-needle 6 by the extruding device 1 and is injected into the treatment part through the micro-needle 6 which is deep into the epidermis. The tube 3 is filled with the liquid medicine and is extruded by the extrusion device 1. Through the circulation operation and multiple times of extrusion, the liquid medicine can smoothly enter the treatment part to carry out covering treatment on the part to be treated, the disease requiring long-time and continuous covering treatment is facilitated, the operation is very convenient, and the operation can be carried out at home. Compared with the method that the medicine is embedded in the micro-needle, the medicine liquid does not need to be treated after the micro-needle 6 is absorbed, can quickly act on an affected part, and can be injected into a treatment part in a circulating mode well.

The operation can be carried out according to actual conditions.

When the pipeline 3 is a hose, a needle base 18 for supporting the microneedle 6 is arranged between the drug inlet end 12 of the microneedle 6 and the pipeline 3, and as shown in fig. 7, the microneedle 6 penetrates through the needle base 18 and is communicated with the pipeline 3. The needle base 18 is made of a material with certain hardness, the upper end face is fixedly connected with the pipeline 3 in a bonding mode and the like, the microneedles 6 can be well supported and fixed, and the problem that the microneedles 6 cannot be well pricked into the skin due to the fact that the microneedles 6 are connected to the pipeline 3 of the full hose and the hose deforms when the microneedles are pressed on the skin is solved. The needle mount 18 may partially wrap around the tube 3, supporting and holding the microneedles 6, as shown in fig. 6. The lower end face can be a horizontal plane, so that the pipeline 3 is more smooth when being pressed on the skin, and the device can be used for tightly adhering the skin. The lower end face can also be designed into a shape with a certain radian, so that the lower end face is matched with some parts which are not smooth and are treated to be attached to the skin, such as the forehead, the elbow and the like, so as to better seal the wound surface.

The needle base 18 may be provided with the lower end of the entire tubing 3; the needle base 18 may be provided only at a portion where the microneedles 6 communicate with the tube 3, which is convenient for cost saving.

The tube 3 may also be a hose, and a combination of a hose and a hard tube is adopted, as shown in fig. 6, the tube 3 includes an upper hose portion 16 and a lower hard tube portion 17, and the drug inlet end 12 of the microneedle 6 is communicated with the lower hard tube portion 17. Because micropins 6 and lower part hard tube portion 17 intercommunication for lower part hard tube portion 17 can be better support and fixed micropins 6, avoid the pipeline 3 aversion when pressing to lead to the problem emergence that micropins 6 can not prick into the skin well. The upper hose portion 16 may occupy two thirds of the conduit 3, and as shown in fig. 6, may collapse by external force to squeeze the liquid medicine in the conduit 3 into the communicating microneedles 6. The lower hard tube part 17 can be designed into a shape with a flat bottom, and can also be designed into a shape with a certain radian by matching with some treatment parts which are not flat, so that the lower hard tube part is more closely contacted with the skin, and the infection of the wound surface is favorably avoided.

The hose assembly of the conduit 3, the upper hose portion 16 and the lower hose portion 17 may be connected by gluing or the like. The mold can also be used for realizing that the tube wall of the upper hose part 16 is arranged to be thinner and the tube wall of the lower hard tube part 17 is arranged to be thicker, so that the upper hose part 16 can be easily collapsed by external force, and the lower hard tube part 17 is not easily deformed to better support the microneedles 6.

By adopting the schemes, the problem that the micro-needle 6 possibly cannot be well stressed on the pipeline 3 when the pipeline 3 is completely a hose is solved, so that the micro-needle 6 can be more easily inserted into the epidermis for treatment.

As shown in fig. 2 or 3, the extrusion apparatus 1 comprises a closed cavity 7 and a negative pressure compressor 14; the negative pressure compression piece 14 is made of compressible materials, is positioned in the closed cavity 7 and wraps the pipeline 3; the closed cavity 7 is provided with an extrusion device connecting port 10 for connecting a negative pressure device; or the closed cavity 7 is connected with an air duct 15 for connecting a negative pressure device. As shown in fig. 3, when the device of the present application is pressed against the skin, the closed chamber 7 and the skin form a closed space enclosing the tube 3 and the negative pressure compressor 14. When the negative pressure device reduces the air pressure in the closed space through the connecting port 10 of the squeezing device or the air duct 15, the negative pressure compressing piece 14 contracts to uniformly apply pressure to the hose part of the pipeline 3, so that the liquid medicine in the pipeline 3 is forced to squeeze into the micro-needle 6, and the micro-needle 6 is filled. When the negative pressure compression piece 14 is not under negative pressure, the volume is larger, so that the closed space is larger; the volume is contracted during negative pressure, the wound surface of a treatment part cannot be pressed, or the compression of the wound surface is buffered to a certain extent, so that the skin is prevented from being damaged due to the long-time compression of the wound surface, and the negative pressure wound-surface compression device is particularly suitable for the situation of needing long-time continuous treatment. And is also beneficial to adding different liquid medicines for a plurality of times according to the treatment requirement. And the negative pressure compression piece 14 has larger pressure applying degree after negative pressure, and can well extrude the liquid medicine into the micro-needle 6 by matching with the extruded hose.

Of course, instead of the negative pressure compressor 14, only the closed cavity 7 may be used to form a closed space for wrapping the pipeline 3, such as a negative pressure sleeve for receiving a quilt.

The negative pressure compressing member 14 may be a sponge or a foam, which is made of a material that shrinks in volume when receiving negative pressure.

Sealed chamber 7 passes through modes fixed connection such as bonding with peripheral pipeline 3, and the rethread is pasted the piece 9 and is fastened this application device on skin to constitute airtight space jointly with skin, also be the sealed protection to the surface of a wound, can effectively avoid the surface of a wound to be infected by the external world. The capsule 7 may also completely enclose the tube, allowing only the microneedles 6 to pass through the capsule 7, thereby forming a sealed space.

The negative pressure compression piece 14 wraps the pipeline 3 at the periphery, and the closed cavity 7 is a transparent cavity, as shown in fig. 3. The negative pressure compression member 14 wraps around the peripheral pipe 3 so as to compress the hose portion around the pipe 3 under negative pressure. The pressure in the entire tube 3 is increased, and the liquid medicine in the tube 3 is pushed into the microneedle 6. The pipeline medicine inlet 8 and the pipeline medicine outlet 11 can be also closed, so that liquid medicine is not easy to extrude from the ports at the two sides when the pressure is increased. Because the negative pressure compression piece 14 only wraps the peripheral pipeline 3 and the sealed cavity 7 is a transparent cavity, the effective pressure of the pipeline 3 by the extrusion device 1 is ensured, and the treatment part is conveniently observed so as to carry out the next-stage dressing change or the treatment scheme change.

Because the microneedle 6 is arranged in a certain covering area after penetrating into the epidermis and the liquid medicine, the microneedle 6 is arranged at a preset angle or at a preset interval, as shown in fig. 4 or 5 or 6 or 7, so that the microneedle 6 can better cover the whole treatment part. As shown in fig. 6 or 7, the same cross section of the pipeline 3 is communicated with the two microneedles 6, and the microneedles are arranged at a preset angle, so that the coverage range of the microneedles 6 injected with liquid medicine is prevented from being repeated, the utilization efficiency of the microneedles 6 is improved, the number of the microneedles is effectively reduced, the cost of the device is reduced, the microneedles 6 and the pipeline 3 are not required to be arranged so densely, and the treated part can be observed more conveniently. The preset angle is an included angle formed by extension lines of the two microneedles 6, can be selected from 10 degrees to 150 degrees, and is actually selected according to the coverage area of the liquid medicine as long as the microneedles 6 can be ensured to penetrate into the epidermis. The microneedles 6 are not arranged at standard equal intervals, the drug outlet end 13 of the microneedle 6 is used as the center of a circle, the coverage range of the liquid medicine is a circle, and the two adjacent microneedles 6 are in a tangent state, so that the drug permeation ranges are not overlapped, as shown in fig. 6 or 7.

Optionally, the extension lines of two microneedles 6 communicated with the same cross section of the pipeline 3 form an included angle of 60 degrees, so that the circle covered by the liquid medicine is in a state of being tangent to the needle tube by taking the needle point as the center of the circle. Since one microneedle 6 can cover a circular coverage treatment area, the liquid medicine coverage repetition of the needle tube can be reduced and the treatment area can be basically covered by adopting the mode. Meanwhile, the microneedles 6 are not too dense, which facilitates observation of the treatment area.

Three microneedles 6 communicating with the same cross-section of the conduit 3, as shown in figure 4. The micro-needle group is set with reasonable preset spacing, thereby the treatment coverage area can be enlarged.

It is also possible to adopt an arrangement of the microneedles 6 as shown in fig. 5, that is, an arrangement of two microneedles 6 and one microneedle 6 arranged at a predetermined angle and a predetermined interval and fitted to the microneedles 6 of the adjacent tubes 3. For example, two microneedles 6 are arranged on the same cross section of the pipe 3 at an included angle of 60 °, and a vertically downward microneedle 6 is arranged at a certain distance, and so on. Since the liquid medicine of the micro-needles 6 is in a circular shape after penetrating into the epidermis to cover the treatment area, the arrangement mode can form the effect of covering the treatment area as shown in fig. 8, and it can be seen that the scheme can basically achieve the full coverage of the treatment part and has few overlapped areas by matching with the staggered arrangement of the micro-needles 6 of the adjacent pipeline 3. The repeated coverage area is reduced while the treatment coverage area of the treatment part is ensured, the number of the micro needles 6 is greatly reduced, and the observation of the treatment part is more convenient.

The arrangement mode of the microneedles 6 can be selected according to actual needs and the needs of the liquid medicine coverage range, and the included angle between the microneedles can be 20-150 degrees, so that the minimum quantity of the microneedles 6 is ensured, and the observation is convenient; or the included angle between the microneedles is 50-120 degrees, so that the number of the microneedles 6 is reduced while the treatment coverage is ensured. Other various arrangement modes can be adopted, and the pipeline 3 can be matched with the staggered design, so that the quantity of the micro-needles 6 is reduced, the cost is saved, and the treated part is easier to observe under the conditions of ensuring the coverage and reducing the repeated coverage.

The microneedles 6 may also be comprised of absorbable materials, including materials that promote epidermal healing. Therefore, the liquid medicine improves the transdermal speed and avoids the non-uniformity of puncture, the liquid medicine is ensured to be uniformly permeated into the wound surface, and the microneedle 6 automatically absorbs the liquid medicine after sending the liquid medicine for a certain time, thereby promoting the healing of the wound surface. Non-absorbable materials may also be used and replaced over time.

The pipeline medicine outlet 11 is provided with a color development device. When the liquid medicine is full of pipeline 3 soon, the liquid medicine makes the color development device colour development to observed by the operator, make things convenient for the operator to annotate the medicine operation to the device of this application.

Before the device is used, anesthesia treatment can be carried out on a treatment part, such as anesthetic is coated on the part, or the sealing layer 5 with the anesthetic is torn off and then coated on the treatment part, so that discomfort caused by the fact that some pain-sensitive patients prick the skin by the microneedle 6 is avoided.

The external pressure pumping and pressurizing devices such as the negative pressure device and the pressurizing device can select an electric negative pressure device or a manual negative pressure device with low force and slow pressure pumping, so that the liquid medicine can not flow into the treatment part too fast through the micro needle 6 due to quick pressure pumping during pressure pumping or pressurizing, and the human body injury is avoided.

The pipeline 3 and the micro-needle 6 also adopt corresponding and safer pipe diameters and lengths, so that the injury to the body caused by excessive injection of part of liquid medicine is avoided. Alternatively, the total volume of the tube 3 and the microneedles 6 containing the liquid medicine at a time is set to a plurality of volume types. The doctor can calculate the dosage of the liquid medicine according to the size of the treatment part, and if 5 ml of liquid medicine is needed; then, the pipeline 3 with the total volume smaller than the medicine amount is selected, and if the pipeline 3 with the total volume of 1 ml is selected, the effect of the required medicine liquid can be achieved through injecting for 5 times. By adopting the mode, the injection of the liquid medicine can be controlled only by dosing the medicine amount by a doctor and without preparation by professional personnel. And compared with the method that the drug dose is fixed when the drug is embedded in the microneedle, the method can be used for injecting proper drug dose in a more targeted manner, and is more flexible and reliable. The treatment effect of the liquid medicine on the treatment part can be well observed by injecting the liquid medicine for multiple times, so that whether the liquid medicine is proper or not and whether the liquid medicine needs to be replaced or not can be determined. A small amount of liquid medicine can be injected first to observe whether anaphylactic reaction exists or not, and then normal injection is carried out, so that the risk of possible damage of the liquid medicine to a human body is reduced to the minimum.

Claims (10)

1. A device for continuously covering and injecting liquid medicine is characterized by comprising

The pipeline (3) comprises a pipe body, a pipeline medicine outlet (11) and a pipeline medicine inlet (8);

a plurality of hollow microneedles (6) distributed at the lower end of the tube (3); the drug inlet end (12) of the micro needle (6) is communicated with the pipeline (3).

2. The device for continuously covering and injecting liquid medicine according to claim 1, further comprising a sealing layer (5) located at the medicine outlet end (13) of the micro-needle (6) for sealing the medicine outlet end (13) of the micro-needle (6).

3. The device for continuously covering and injecting liquid medicine according to claim 2, wherein the pipeline (3) is a pre-vacuum pipe, the pipeline medicine inlet (8) is provided with a sealing film, and the pipeline medicine outlet (11) is sealed.

4. A device for the continuous covering infusion of medical liquids according to claim 1, characterized in that it comprises extrusion means (1) partially or totally enveloping said duct (3); the pipeline (3) is partially or completely a hose.

5. The device for continuously covering and injecting liquid medicine according to claim 4, characterized in that a needle base (18) for supporting the micro needle (6) is arranged between the medicine inlet end (12) of the micro needle (6) and the pipeline (3).

6. A device for continuously covering and injecting medical liquid according to claim 4, characterized in that said tube (3) comprises an upper hose portion (16) and a lower hard tube portion (17), said inlet end (12) of said micro-needle (6) is communicated with said lower hard tube portion (17).

7. Device for the sustainable covering of infusion solutions according to claim 4, characterized in that said extrusion device (1) comprises a closed chamber (7) and a negative pressure compressor (14); the negative pressure compression piece (14) is made of compressible materials, is positioned in the closed cavity (7) and wraps the pipeline (3); the closed cavity (7) is provided with an extrusion device connecting port (10) for connecting a negative pressure device; or the closed cavity (7) is connected with an air duct (15) for connecting a negative pressure device.

8. Device for the continuous covering infusion of medical liquids according to claim 7, characterized in that said negative pressure constriction (14) surrounds said peripheral duct (3) and said closed chamber (7) is a transparent chamber.

9. The device for continuous covering infusion solutions of claim 1 characterized in that said microneedles (6) are arranged in preset angles and preset intervals.

10. A device for continuously covering and injecting liquid medicine according to claim 1, characterized in that the medicine outlet (11) of the pipeline is provided with a color developing device.

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