JPH08511418A - 生分解性極微粒子からのアンチセンスオリゴデオキシリボヌクレオチドの徐放運搬による長期作用のある処置 - Google Patents

生分解性極微粒子からのアンチセンスオリゴデオキシリボヌクレオチドの徐放運搬による長期作用のある処置

Info

Publication number
JPH08511418A
JPH08511418A JP6523540A JP52354094A JPH08511418A JP H08511418 A JPH08511418 A JP H08511418A JP 6523540 A JP6523540 A JP 6523540A JP 52354094 A JP52354094 A JP 52354094A JP H08511418 A JPH08511418 A JP H08511418A
Authority
JP
Japan
Prior art keywords
antisense
oligodeoxyribonucleotides
cells
lactic acid
ultrafine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP6523540A
Other languages
English (en)
Japanese (ja)
Inventor
アモス、マイケル・デービッド
マッケリゴット、サンドラ・ガートルード
Original Assignee
メディソーブ・テクノロジーズ・インターナショナル・リミテッド・パートナーシップ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by メディソーブ・テクノロジーズ・インターナショナル・リミテッド・パートナーシップ filed Critical メディソーブ・テクノロジーズ・インターナショナル・リミテッド・パートナーシップ
Publication of JPH08511418A publication Critical patent/JPH08511418A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
JP6523540A 1993-04-19 1994-04-19 生分解性極微粒子からのアンチセンスオリゴデオキシリボヌクレオチドの徐放運搬による長期作用のある処置 Pending JPH08511418A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4767293A 1993-04-19 1993-04-19
US08/047,672 1993-04-19
PCT/US1994/004287 WO1994023699A1 (fr) 1993-04-19 1994-04-19 Traitement a action prolongee par apport a liberation lente d'oligodesoxyribonucleotides anti-sens a partir de microparticules biodegradables

Publications (1)

Publication Number Publication Date
JPH08511418A true JPH08511418A (ja) 1996-12-03

Family

ID=21950303

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6523540A Pending JPH08511418A (ja) 1993-04-19 1994-04-19 生分解性極微粒子からのアンチセンスオリゴデオキシリボヌクレオチドの徐放運搬による長期作用のある処置

Country Status (6)

Country Link
EP (1) EP0695170A4 (fr)
JP (1) JPH08511418A (fr)
AU (1) AU6637394A (fr)
CA (1) CA2160877A1 (fr)
NZ (1) NZ265555A (fr)
WO (1) WO1994023699A1 (fr)

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US6916490B1 (en) 1998-07-23 2005-07-12 UAB Research Center Controlled release of bioactive substances
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GB0719367D0 (en) 2007-10-03 2007-11-14 Procarta Biosystems Ltd Transcription factor decoys, compositions and methods
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US9567631B2 (en) 2012-12-14 2017-02-14 10X Genomics, Inc. Methods and systems for processing polynucleotides
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US10323279B2 (en) 2012-08-14 2019-06-18 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10273541B2 (en) 2012-08-14 2019-04-30 10X Genomics, Inc. Methods and systems for processing polynucleotides
WO2014052875A1 (fr) * 2012-09-27 2014-04-03 Cynvenio Biosystems, Inc. Microparticules sensibles à un stimulus et procédés d'utilisation
US10533221B2 (en) 2012-12-14 2020-01-14 10X Genomics, Inc. Methods and systems for processing polynucleotides
WO2014124338A1 (fr) 2013-02-08 2014-08-14 10X Technologies, Inc. Génération de codes à barres de polynucléotides
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Also Published As

Publication number Publication date
CA2160877A1 (fr) 1994-10-27
EP0695170A4 (fr) 1998-08-19
EP0695170A1 (fr) 1996-02-07
NZ265555A (en) 1997-09-22
AU6637394A (en) 1994-11-08
WO1994023699A1 (fr) 1994-10-27

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