JPH08299422A - Anti-fungal aromatic agent - Google Patents

Abstract

PURPOSE: To provide a product which emits aroma in a room for a long time and is excellent on anti-fungal properties by mixing an aromatic powder prepd. by adsorbing a perfume on a carrier and an anti-fungal powder consisting of a cyclodextrin inclusion compd. being a volatile anti-fungous agent and molding the mixture into a specified shape. CONSTITUTION: An anti-fungal aromatic agent is prepd. by mixing an aromatic powder prepd. by adsorbing a perfume on a carrier and an anti-fungal powder consisting of a cyclodextrin inclusion compd. being a volatile anti-fungous agent and molding the mixture into a specified shape. Then, as a method for inclusion of a perfume into cyclodextrin, it is pref. that a high speed countercurrent type stirring tank 1 is used and a flow being approximately parallel to the rotating shaft 3 of a turbine 4 is formed by means of the blades 4b of the turbine 4 rotating in a mixed liq. 1a of a cyclodextrin water soln. and the perfume and while the mixed liq. 1a is made to flow convectionally, it is stirred by the apex part of the blades 4b moving in the direction being approximately at right angles to the flow direction. It is possible thereby to improve the inclusion ratio indicating the ratio of the actual amt. of inclusion of the perfume at least 60%.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a novel antibacterial fragrance, and more particularly to an antibacterial fragrance which is molded into a shape such as a tablet and diffuses an aromatic component and an antibacterial component indoors in the presence of water.

[0002]

2. Description of the Related Art Conventionally, various fragrances have been used to give a good scent in a room. Such fragrances are usually those which volatilize liquid fragrances or sublimate solid fragrances at room temperature or by heating. However, such a fragrance causes a large amount of fragrance to be released at one time, and thus has a problem that the fragrance cannot be gradually released over a long period of time. In order to solve such a problem, Japanese Patent Publication No. 4-58344 proposes to encapsulate a perfume clathrate compound in a hollow porous substance such as silica for sustained release. However, even with such a constitution, the sustained release property of the fragrance was insufficient.

On the other hand, in a refrigerator or the like or in a room where foods are handled, it is required to eliminate the malodor in the room, prevent the generation of mold and the growth of bacteria, and keep the room clean. An object of the present invention is to solve the above-mentioned technical problems and to provide an antibacterial fragrance which is capable of spreading an aroma in a room for a long time and is also excellent in antibacterial properties.

[0004]

Means and Actions for Solving the Problems As a result of intensive studies to solve the above problems, the present inventors have found that an aromatic powder having a fragrance adsorbed on a carrier and an antibacterial agent having volatility are contained. The antibacterial fragrance mixed with the antibacterial powder having the specified characteristics and molded into a predetermined shape such as a tablet emits a fragrance component and an antibacterial component by adding water or absorbing indoor humidity, and The inventors have found a new fact that divergence is maintained for a long time, and have completed the present invention.

That is, the antibacterial fragrance of the present invention is prepared by mixing an aromatic powder having a carrier adsorbed with a fragrance and an antibacterial powder made of a cyclodextrin clathrate compound, which is a volatile antibacterial agent, into a predetermined shape. It is characterized by being molded into. Further, the other antibacterial fragrance of the present invention comprises an aromatic powder in which a fragrance is adsorbed on a carrier, and an antibacterial powder composed of a cyclodextrin inclusion compound of a volatile antibacterial agent and amorphous calcium phosphate. It is characterized by being mixed and molded into a predetermined shape.

Still another antibacterial fragrance of the present invention is an aromatic powder composed of a cyclodextrin inclusion compound which is a fragrance, and an antibacterial composed of a cyclodextrin inclusion compound which is a volatile antibacterial agent and amorphous calcium phosphate. It is characterized in that it is mixed with a powdery powder and shaped into a predetermined shape. Hereinafter, the antibacterial aromatic agent of the present invention will be described in detail.

First, the aromatic powder will be described. The fragrance used in the present invention, for example, peppermint, petitgrain, citronella, spearmint, lime, mandarin and the like refreshing mood,
Benzo, geranium, frankincense (Olibanum), sandalwood (Sandalwo
od), marjoram, lavender, lavandine and other relaxing fragrances, sweet orange, German chamomile, roman chamomile, linden and other soothing scents, fennel, cardamom, clary sage, black pepper, juniper, patchouli,
Hyssop, Melissa, Myrrha, Coriander,
Tonic and vibrant fragrances such as Angie Erica root, star anise, tarragon, sassafras, ylang ylang, bitter orange, jasmine, damask rose, china rose, buty bar, tuberose, violet leaf, almond bitter, vanilla, balsam, etc. Fragrances, basil, that help raise your mood and help you create a mood
Fragrances such as rosemary and laurel that help improve concentration, air freshness fragrances such as cypress, camphor, bergamot, eucalyptus, rosewood, niuli, cedar leaf and cinnamon leaf, as well as karamas root, orris root and green herbs , Fragrances such as floral.

[0008] Examples of the carrier include powdery carriers such as amorphous calcium phosphate (hereinafter referred to as ACP), and it is particularly preferable to use ACP in order to impart high sustained release property. The ACP is prepared by granulating a slurry containing ACP fine particles. The above-mentioned slurry contains 0.1 to 10% by weight, preferably 0.1 to 3% by weight, of a dispersant (for example, ammonium triacrylate salt) which is a water-soluble polymer in a suspension of calcium hydroxide under stirring. After addition to obtain a mixed solution, the mixed solution was prepared by adjusting the pH to 10 to 5 by dropping a phosphoric acid aqueous solution under stirring, and the particle size was about 0.1 μm or less.
Contains fine particles.

From the diffraction pattern of the powder X-ray analysis method, the ACP fine particles are calcium phosphate, and the pattern is broad, and the crystals of hydroxyapatite and tricalcium phosphate [Ca ₃ (PO ₄ ) ₂
Since it is different from the diffraction pattern of [nH ₂ O], it is confirmed to be amorphous calcium phosphate. As the granulation method of ACP, the obtained particles are porous and have a particle size of 20.
It has a substantially spherical shape of 0 μm or less, preferably 8 to 200 μm, and has a specific surface area of 10 m ² / g or more, preferably 70 m ² / g.
There is no particular limitation as long as it is capable of the above, and for example, a spray drying granulation method, a granulation method of pulverizing after freeze-drying, a high-speed stirring granulation method, and the like can be used. In the spray drying granulation method, the blast temperature is 100 to 350 ° C.
Therefore, it is preferable to set the exhaust air temperature to about 50 to 120 ° C.

The perfume is adsorbed on the carrier in the form of a dispersion in which a surfactant and water are added. Surfactants are used to enhance the dispersibility and dispersion stability of fragrances in water. Examples of such a surfactant include a nonionic surfactant,
Anionic surfactants and the like can be mentioned, and they can be used alone, but in the present invention, a nonionic surfactant excellent in dispersibility and an anionic surfactant contributing to dispersion stabilization are used in a weight ratio. It is preferable to mix and use it at a ratio of about 9: 1 to 5: 5.

Examples of the nonionic surfactant include polyoxyethylene alkyl ether, polyoxyethylene alkylphenyl ether, polyoxyethylene polyoxypropylene ether, polyoxyethylene glycerin fatty acid ester, polyethylene glycol fatty acid ester and the like. Examples of the anionic surfactant include fatty acid soap, alkylbenzene sulfonate, alkylnaphthalene sulfonate, dialkylsulfosuccinate ester salt, higher alcohol sulfate ester salt, alkyl ether sulfate salt, polyoxyethylene alkylphenyl ether sulfate salt, Examples thereof include alkyl ether phosphate salts. The alkyl group is preferably a linear or branched alkyl group having 8 to 22 carbon atoms.

The surfactant is used in the water in an amount of 50 to 200 parts by weight, preferably 80 to 150 parts by weight, per 100 parts by weight of the fragrance. Water is used in an amount of 10 to 1000 parts by weight, preferably 30 to 500 parts by weight, based on 1 part by weight of the fragrance. Mixture of fragrance, surfactant and water is 10 per 100 parts by weight of carrier.
Mix at a ratio of 150 parts by weight and adsorb on a carrier. The mixing is performed using, for example, a pole mill. At this time, the ratio of the fragrance to the carrier varies depending on the kind of the fragrance used, but the fragrance is usually 0.00 per 100 parts by weight of the carrier.
Suitably, it is from 01 to 10 parts by weight.

Next, the case of using a cyclodextrin inclusion compound as a fragrance as the aromatic powder will be described.
The inclusion method of the fragrance in the cyclodextrin is as follows: A high-speed convection stirrer is used, and mixing is carried out in a mixture of the cyclodextrin aqueous solution and the fragrance by a blade of a turbine that is substantially parallel to the rotating shaft of the turbine. A method of stirring the mixed liquid by the tip of the blade of the turbine that moves in a direction substantially perpendicular to the flow direction of the mixed liquid while forming a liquid flow to convect the mixed liquid in the stirring tank is described. It is preferable to adopt it. As a result, the inclusion rate showing the ratio of the actual inclusion amount of the fragrance is improved to about 60% or more, preferably about 80% or more, as compared with the usual mixing method of kneading the cyclodextrin and the fragrance. Can be made.

That is, 1 part by weight of cyclodextrin and 1 to 10 parts by weight of water are mixed to prepare a mixed solution in which cyclodextrin is dispersed in water, and the mixed solution is mixed with a convection stirrer at a turbine speed of 500 to 20000 rpm. While stirring at the number of rotations, 0.01 to 0.2 parts by weight of the fragrance was gradually added to 1 part by weight of cyclodextrin, and after the addition was completed, stirring was continued for 10 to 3 hours to give an inclusion rate. A mixed solution containing 60% or more of the inclusion compound is obtained.

FIG. 1 shows the agitator. As shown in the figure, it has a bottomed cylindrical stirring tank 1 and a stirring section 2 which is detachable from the stirring tank 1. The stirring unit 2 is
A drive shaft 3 provided with a motor (not shown) is connected to the rotary shaft of the motor, and the drive shaft 3 is attached to the tip of the drive shaft 3.
And a turbine 4 that rotates integrally with. The turbine 4 is a disc-shaped base portion 4 a that rotates integrally with the drive shaft 3.
And a plurality of blades 4b provided around the base 4a. The blades 4b are for convection and stirring the mixed liquid 1a in the stirring tank 1, and the base 4a
With respect to the base portion 4a, that is, in a radial direction outward with respect to the base portion 4a, and in a direction in which the drive shaft 3 is separated in the rotational axis direction.

In addition, the agitator 2 has a substantially cylindrical stator 5 that drives the drive shaft 3 so as to rotatably support the turbine 4.
A plurality of stator lots 6 are provided coaxially with each other and for fixing the stator 5 to a motor support (not shown) at predetermined intervals. The stator 5 is provided with a cylindrical bearing portion 5a for rotatably supporting the turbine 4, and the bearing portion 5a is provided.
A discharge passage 5b for the mixed liquid is formed by the outer peripheral surface of the and the inner peripheral surface of the stator 5. On the other hand, a suction port 5c having a diameter smaller than the inner circumference of the stator 5 is formed at the tip of the stator 5.

Further, in the stirring section 2, a radial baffle-shaped commutation plate 7 for smoothly convection of the mixed liquid is provided between the motor support base (not shown) and the stator 5.
The drive shaft 3 and the respective stator lots 6 are provided so as to penetrate therethrough and are movable along the direction of the rotation axis of the drive shaft 3.
A lock mechanism (not shown) that can temporarily fix the commutation plate 7 at a predetermined position is attached to the commutation plate 7.

The stirring unit 2 is attached to the stirring tank 1 coaxially with the turbine 4 inserted from above in the vicinity of the bottom of the stirring tank 1, and the flow of the mixed liquid from the turbine 4 is further increased. The commutation plate 7 is set so that the direction is changed to the inner wall of the stirring tank 1 in the upper layer of the mixed liquid 1a in the stirring tank 1. Next, the operation of the agitator will be described. The pressure difference between the two surfaces of the blades 4b of the turbine 4 caused by the high speed rotation of the turbine 4 acts like a pump, and the mixture liquid 1a in the agitation tank 1 is statored. 5 is sucked through a suction port 5c which is a lower part of the stator 5, and is discharged upward from an upper discharge port of the stator 5.

The rising flow of the mixed liquid 1a is changed by the commutation plate 7 on the upper surface, descends along the inner surface of the stirring tank 1, and reaches the bottom of the stirring tank 1 again. The mixed liquid 1a in the stirring tank 1 is constantly stirred while convection. At this time, the blades 4b that rotate at a high speed with respect to the stator 5 rotate and move so as to cross the flow of the mixed liquid 1a at a substantially right angle, and thus the blades 4b are
A strong shearing force, impact, or turbulence can be generated on the flowing mixed liquid 1a, whereby the mixed liquid 1
When a is stirred, the size of the oil droplets made of the fragrance contained in the mixed liquid 1a can be reduced. As a result, the inclusion rate of the fragrance can be increased to 60% or more.

Examples of the cyclodextrin include α-cyclodextrin, β-cyclodextrin, γ-cyclodextrin and the like, and these may be used as a mixture of two or more kinds. In the present invention, it is preferable to use β-cyclodextrin and γ-cyclodextrin from the viewpoint of sustained release. In terms of cost, it is preferable to use β-cyclodextrin.

By changing the content of cyclodextrin in the mixed solution 1a within a range of 1 to 90% by weight, an inclusion compound having a desired average particle size can be obtained. When the proportion of cyclodextrin is 90% by weight or more, the viscosity of the mixed solution becomes high, which makes granulation difficult. The clathrate compound is mixed with the powder of ACP in the form of the above mixed solution to complex the clathrate compound with ACP. ACP is
It is preferably 1 to 100 parts by weight with respect to 100 parts by weight of the inclusion compound.

The aromatic powder according to the present invention obtained by these methods has an average particle size of about 8 to 200 μm.
Next, the antibacterial powder in the present invention will be described. The antibacterial powder in the present invention comprises a volatile antibacterial agent cyclodextrin inclusion compound, or a volatile antibacterial agent cyclodextrin inclusion compound A
It consists of CP.

Examples of the volatile antibacterial agent include allyl isothiocyanate [CH ₂ ═CHCH ₂ NCS], which is volatile at room temperature and has a bactericidal / bacteriostatic action, hinokitiol, hiba oil, peach oil, and penny royal. , Lemongrass, lemon, spiked lavender, nutmeg, oregano, sage, ginger, savory, thyme, allspice, cedarwood, cinnamon bark, clovebuds, cayubte, pine, tea tree, terpenes and so on. In the present invention,
Particularly, it is preferable to use allyl isothiocyanate, which is an extract component of wasabi, in order to impart high antibacterial properties.

The cyclodextrin inclusion compound which is a volatile antibacterial agent can be prepared in the same manner as the cyclodextrin inclusion compound which is a fragrance described above. On the other hand, an antibacterial powder composed of a volatile antibacterial agent cyclodextrin inclusion compound and ACP is prepared as follows. That is, cyclodextrin is added to the slurry containing the same ACP fine particles as used above, and the turbine of the agitator is rotated at a rotation speed of 500 to 20000 rpm by the above-mentioned convection high-speed agitator to obtain a cyclodextrin-added slurry. . The above-mentioned antibacterial agent is gradually added to this slurry, and the clathrate slurry in which the antibacterial agent is included in cyclodextrin is granulated to obtain an antibacterial powder.

The antibacterial agent is dissolved in an alcohol which is freely miscible with water and added to the slurry at room temperature. Another method is to obtain antibacterial powder by mixing ACP particles obtained by granulating a slurry containing the above ACP particles with cyclodextrin clathrating an antibacterial agent.

The weight ratio of the antibacterial powder and the aromatic powder thus obtained is from 1: 1 to 30, preferably from 1: 1.
The antibacterial aromatic agent of the present invention is obtained by uniformly mixing at a ratio of about 20 and then by a pressing machine or the like to form an arbitrary shape such as a tablet shape or a plate shape. The aromatic powder and the antibacterial powder may be mixed in a slurry state, and after mixing, they are dried and molded.

The antibacterial fragrance of the present invention can release the fragrance component and the antibacterial component indoors by water addition or moisture absorption. In that case, you may heat with an electric heater etc. Further, the moisture absorption does not need to be under high humidity, and can be effectively diffused even in an environment of medium, for example, humidity of about 60%. When heating, the temperature is usually 30 to 10
It is suitable to be about 0 ° C.

[0028]

【Example】

Example 1 1 g of lavender as a fragrance and 1 g of an aqueous solution of a surfactant were thoroughly mixed with a spatula, to which 50 g of water was added and further mixed. The obtained aqueous solution was treated with amorphous calcium phosphate (Apamicron AP manufactured by Sekisui Plastics Co., Ltd.).
-20 C, particle size 20 μm, specific surface area 70 m ² / g) 1
In addition to 00 g, it was thoroughly mixed to obtain a slurry of aromatic powder, which was granulated to obtain an aromatic powder having an average particle size of 20 μm.

The above aqueous solution of the surfactant is POE
(10) 70% by weight of a 20:70 mixture of sodium alkyl ether sulfate (wherein the carbon number of the alkyl group is 10 to 13) and POE (10) nonylphenyl ether, 20% by weight of sodium di-2-ethylhexyl sulfosuccinate. And 10% by weight of water. On the other hand, a cyclodextrin inclusion compound of allyl isothiocyanate was prepared using the stirrer shown in FIG. First, purified water 150
0 g and β-cyclodextrin 900 g were charged into the stirring tank 1, the turbine 4 was rotated at 5000 rpm,
100 g of allyl isothiocyanate was gradually added while stirring the mixed solution 1a composed of purified water and β-cyclodextrin, and the turbine 4 was further rotated at 5000 rpm and stirred for 90 minutes, and isothiocyanate was mixed in the mixed solution 1a. A slurry of antibacterial powder in which allyl acid was included in cyclodextrin was obtained and granulated to obtain antibacterial powder having an average particle size of 20 μm.

The obtained aromatic powder and antibacterial powder were mixed 9:
1), and mix this mixture with a press machine at a diameter of 1.2c
m to form a tablet having a thickness of 2 mm to obtain an antibacterial aromatic agent. An Omni mixer (manufactured by Chiyoda Giken Kogyo Co., Ltd.) was used for mixing. Example 2 An antibacterial aromatic agent was obtained in the same manner as in Example 1 except that the aromatic powder and the antibacterial powder were mixed at 5: 5. Example 3 An aqueous phosphoric acid solution diluted 2 to 4 times with water was added dropwise to a stirred calcium hydroxide suspension to adjust the pH to around 11.
Subsequently, an aqueous phosphoric acid solution diluted 5 to 8 times with water was added dropwise to the suspension to adjust the pH to 10 to 9, and triacrylic acid as a dispersant which is a weakly alkaline water-soluble polymer. Ammonium salt is 0.5 for ACP particles
A so that the particle size is 0.1 μm or less
A slurry in which CP fine particles were stably dispersed was obtained.

This slurry was diluted with ion-exchanged water so that the ACP concentration was adjusted to 10% by weight.
CP slurry was obtained, and β was added to 1500 g of this ACP slurry.
-Disperse 100 g of cyclodextrin, gradually add 10 g of allyl isothiocyanate while convectively stirring at 5000 rpm with a homomixer, and continue stirring for 90 minutes to allow allyl isothiocyanate to be included in β-cyclodextrin. Then, as shown in FIG.
An inclusion product slurry 13 containing the fine particles 11 and the cyclodextrin inclusion compound 12 of allyl isothiocyanate was obtained.

Then, the clathrate slurry 13 was supplied to the spray dryer 15 (L-8 manufactured by Okawara Kako Kikai Co., Ltd.) by the metering pump 14 (supply amount: 1 to 3 kg / hour). The atomizer 16 of the spray dryer 15 is rotated at a high speed, and the clathrate slurry 13 is granulated and dried by a spray granulation method in which a hot air flow for drying in the spray dryer 15 is sprayed to dry the granules. An antibacterial powder 17 (ACP compounding amount 10%) containing the contact compound 12 was obtained.

The hot air used in the spray granulation method is supplied by heating the air sucked from the outside through the air filter 19 by the electric heater 20. At this time, the inlet temperature of the hot gas chamber 21 is controlled to 180 ° C., and the outlet temperature of the discharge hole 22 connected to the cyclone 18 is controlled to 70 ° C. The rotation speed of the atomizer 16 is 250.
It was set to 00 rpm.

The antibacterial powder 17 thus obtained had a substantially spherical shape, and the cyclone 18 collected the powder having an average particle size of about 15 μm. In the antibacterial powder 17, it is estimated that part of allyl isothiocyanate is adsorbed by ACP. The obtained antibacterial powder 17 and the aromatic powder prepared in the same manner as in Example 1 were mixed at a ratio of 1: 9 (weight ratio), and this mixture was pressed with a press to have a diameter of 1.2c.
m to form a tablet having a thickness of 2 mm to obtain an antibacterial aromatic agent. An Omni mixer (manufactured by Chiyoda Giken Kogyo Co., Ltd.) was used for mixing. Example 4 Except that the antibacterial powder 17 and the aromatic powder prepared in the same manner as in Example 1 were mixed at a ratio of 5: 5 (weight ratio),
An antibacterial fragrance was obtained in the same manner as in Example 3. Example 5 A slurry in which the same ACP fine particles as used in Example 3 were dispersed was diluted with ion-exchanged water to obtain an ACP slurry adjusted to have an ACP concentration of 20% by weight. This A
ACP obtained by granulating the CP slurry by the spray granulation drying method with the spray dryer 5 in the same manner as in Example 3.
Particles (average particle size: about 17 μm) were obtained.

Further, for β-cyclodextrin,
The mixture added with 10% by weight of allyl isothiocyanate dissolved in ethanol was dried under reduced pressure,
Crush the ACP particles to the same size as the average particle size,
Inclusion body particles (average particle diameter: about 16 μm) were obtained. Then,
The ACP particles and the clathrate particles were put into an Omni mixer (manufactured by Chiyoda Giken Kogyo Co., Ltd.) at a ratio of 1: 1 and uniformly mixed to obtain an antibacterial powder (ACP blending amount: 10%).

On the other hand, in the same manner as in Example 1 except that 100 g of hinokitiol as a fragrance was used in place of 100 g of allyl isothiocyanate in Example 1, an average particle size of 20 μ in which hinokitiol was included in cyclodextrin.
m aromatic powder was obtained. The above antibacterial powder and aromatic powder were mixed in a ratio of 1: 9 (weight ratio), and this mixture was molded into a tablet shape having a diameter of 1.2 cm and a thickness of 2 mm with a press machine to give an antibacterial aromatic agent. Obtained. An Omni mixer (manufactured by Chiyoda Giken Kogyo Co., Ltd.) was used for mixing. Example 6 An antibacterial aromatic agent was obtained in the same manner as in Example 5, except that the antibacterial powder and the aromatic powder were mixed at a ratio of 5: 5 (weight ratio).

When the antibacterial fragrance obtained in each of these examples was left in a room at room temperature and a humidity of 55%, the fragrance component and the antibacterial component were diffused in the room for about 5 hours.

[0038]

The fragrance of the present invention has the effect of being able to diffuse the fragrance component and the antibacterial component indoors for a long time under a proper humidity.

[Brief description of drawings]

FIG. 1 is a schematic cross-sectional view of a stirrer used for inclusion of a fragrance in cyclodextrin.

FIG. 2 is a schematic explanatory diagram of a spray dryer for producing antibacterial powder in Example 3.

[Explanation of symbols]

 1 Stirring Tank 1a Mixed Liquid 4 Turbine 4b Blade 11 ACP Particle 12 Inclusion Compound 15 Spray Dryer 17 Antibacterial Powder

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[Procedure amendment]

[Submission date] May 19, 1995

[Procedure Amendment 1]

[Document name to be amended] Statement

[Correction target item name] 0009

[Correction method] Change

[Correction content]

[0009] The ACP particles are calcium phosphate from the diffraction pattern by the powder X-ray analysis, also, since the pattern is broad, and differs from hydroxyapatite and tricalcium phosphate crystal diffraction pattern of the non It is confirmed to be crystalline calcium phosphate. As the ACP granulation method, the obtained particles are porous and have a particle size of 200 μm or less, preferably 8 to 200.
There is no particular limitation as long as it has a substantially spherical shape of μm and a specific surface area of 10 m ² / g or more, preferably 70 m ² / g or more. For example, spray drying granulation method, freeze drying followed by pulverization A granulation method, a high-speed stirring granulation method, or the like can be used. In the spray-drying granulation method, it is preferable that the blast temperature is 100 to 350 ° C and the exhaust air temperature is about 50 to 120 ° C.

Claims (4)

[Claims] 1. An antibacterial characterized by mixing an aromatic powder having a fragrance adsorbed on a carrier and an antibacterial powder made of a cyclodextrin clathrate compound, which is a volatile antibacterial agent, and molding the mixture into a predetermined shape. Sex fragrance. 2. An aromatic powder in which a fragrance is adsorbed on a carrier and an antibacterial powder composed of a cyclodextrin clathrate compound which is a volatile antibacterial agent and amorphous calcium phosphate are mixed and molded into a predetermined shape. An antibacterial air freshener characterized by the following. 3. The antibacterial aromatic agent according to claim 1, wherein the carrier is amorphous calcium phosphate. 4. An aromatic powder composed of a cyclodextrin clathrate compound as a fragrance and an antibacterial powder composed of a cyclodextrin clathrate compound of a volatile antibacterial agent and amorphous calcium phosphate are mixed to obtain a predetermined shape. An antibacterial fragrance characterized by being molded.