JPH08280793A - Bicarbonate dialyzate preparing device for large number of people - Google Patents

Abstract

PURPOSE: To make it possible to supply a large volume of a sodium bicarbonate soln. with a small-sized equipment by forming a sodium bicarbonate powder liquid in a dissolving chamber, occasionally diluting this liquid to form a sodium bicarbonate soln. of a prescribed concn. and mixing this soln. with a dialyzate, thereby preparing the dialyzate of a prescribed mixing ratio. CONSTITUTION: The powder (PB) of the sodium bicarbonate and water W are supplied to the dissolving vessel 10 and are stirred by a stirring means 22 to form the sodium bicarbonate soln. (B soln.) of the prescribed concn. In such a case, a discharge line 30 provided with a degassing means 28 so as to communicate a block chamber 26 with a position upper than the prescribed water level is disposed on the outside of the dissolving chamber 10 to allow the air in the block chamber 26 to escape. The B soln. is sent via a liquid taking-out line 32 to a dialyzate preparing means 40. The stirring means 22 is operated and the B concd. soln. is replenished to the block chamber 26 via a filter 24 when the B soln. in the block chamber 26 decreases. The water level in the dissolving vessel 10 is controlled by controlling the opening and closing of a control valve 28 by the detection signals of a lower limit level detector 20b and an upper limit level detector 20a.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention is an apparatus for obtaining a bicarbonate dialysate for use in hemodialysis, which is a bicarbonate dialysate for a large number of people for preparing a dialysate from sodium bicarbonate powder and water. It relates to an adjusting device.

[0002]

2. Description of the Related Art Today, dialysis solutions used for dialysis include those that do not contain sodium bicarbonate (hereinafter referred to as "A agent").
2 that contains sodium bicarbonate (hereinafter referred to as agent B)
Bicarbonate dialysate prepared from various types of dialysis agents is often used.

The usual adjustment of bicarbonate dialysate is
Each liquid of agent A and agent B adjusted to a predetermined concentration (hereinafter referred to as solution A,
Liquid B) is transferred to the dialysate adjusting means, and liquid A, solution B, and water are each brought to a predetermined ratio (usually A
Liquid: B liquid: water = 1: 1.26: 32.74).

Recently, as the B agent, B powder prepared by formulating only sodium bicarbonate into powder (hereinafter referred to as "B powder") was purchased without purchasing B solution adjusted to a predetermined concentration. In many cases, what is dissolved and diluted by using a sodium dissolving means (hereinafter, referred to as B powder dissolving means) is used as the solution B.

A large amount of dialysate is required for dialysis, and a large amount of liquid B (usually about 5 liters per patient per dialysis) is consumed. In addition, for many patients, it is usual to administer about 5 hours of dialysis treatment twice a day.
Some facilities provide dialysis treatment three times a day.

Therefore, a very large tank is required to adjust the liquid B consumed at one time to one time, and the liquid B has a problem in stability. It is practiced to dissolve the B powder to prepare the B liquid. The B-end dissolving means is a tank of 100 to 300 liters containing a predetermined amount of water and B.
This is a method in which powder is added and stirred to obtain a solution B having a predetermined concentration (often 7 W / V% and often 5.8 W / V%).

In the dialysis of a large number of patients, the number of patients who receive dialysis treatment is not always the same for each dialysis, and it is adjusted to one time.
It is also necessary to change the amount of liquid. Therefore, the above-mentioned dissolution method requires a large space and requires a lot of nerves to measure the amount of water and B powder each time it is dissolved, which is a troublesome work.

It is advantageous in terms of space saving that the amount of the B liquid to be adjusted at one time by the B powder dissolving means is small. From such a viewpoint, a continuous sodium bicarbonate dissolving device has been proposed as a device for automatically dissolving the B powder at any time during dialysis to obtain a liquid B having a predetermined concentration (Japanese Patent Publication No. 1-55893).

In this continuous melting apparatus, the powder B is supplied to the dilution tank by the powder supply means such as a powder feeder and the water is supplied to the dilution tank by the water supply means, and the powder supply means or the water supply means is controlled according to the concentration after stirring. Then, by dispensing sodium bicarbonate or water, the liquid B having a predetermined concentration is obtained. The solution B is transferred from the dilution tank to the storage tank, and the solution B is supplied from the storage tank to the dialysate regulator in the next step. These series of operations are repeated during dialysis.

However, since the solution and concentration are adjusted by the batch method, the structure and operation are complicated, and at the same time, a storage tank having a capacity larger than that of the liquid B adjusted in the dilution tank is required.

In recent years, large-scale dialysis equipment has been increased, and a B-end dissolving means capable of supplying a larger amount of B solution while reducing the occupied space has been desired. In the proposed batch method, the larger the amount of liquid B supplied, the more restricted the time required for scale-up, dissolution, and concentration adjustment of the dilution tank and storage tank.

Further, as the technical background of the present invention, in response to the case where the concentration of the B liquid concentrate obtained thereby changes while dissolving the B powder during dialysis, the concentration of the concentrated liquid at the time of adjusting the dialysate is changed. A system for adjusting a fluid for medical treatment and a cartridge used for the system have been proposed for adjusting a mixing amount to obtain a liquid mixture having a predetermined concentration (Japanese Patent Application Laid-Open No. 6-69242).
3-194666).

This is because water is supplied from a water source to a cartridge inlet containing a sufficient amount of B powder for one dialysis, and the supplied water is dissolved by contacting with the B powder, and is almost discharged at the cartridge outlet. It becomes a saturated liquid with a saturated concentration. This concentrated liquid is mixed with water at the mixing point via the flow rate adjusting means provided on the downstream side of the cartridge, and the measuring means located downstream of this mixing point measures the solution concentration of the mixed liquid,
The flow rate adjusting means is controlled in accordance with the measured concentration value to obtain a solution having a predetermined concentration. However, this type of proposal is intended for application to a single-use dialyzer, which has the function of dialysate preparation and the function of a dialyzer for one patient.

[0014]

However, in the above-mentioned conventional dialysate adjusting device, a device for adjusting dialysate for a large number of patients (dialysate adjusting device for a large number of people).
As is difficult to apply. In particular, there are problems with the following points.

In dialysis of a large number of patients, the amount of dialysate consumed per unit time changes as the number of patients undergoing treatment during dialysis increases or decreases.

In order to deal with this, in the dialysate regulator for a large number of people, the adjusted dialysate is temporarily stored in a storage tank, and the dialysate is transferred from the storage tank to the dialyzer. The system is adopted to replenish the dialysate to the storage tank by restarting the adjustment.

However, in the above system,
It has a function to continuously adjust the dialysate, and in the dialysate adjuster for a large number of people, the B end amount used in one dialysis often changes, and therefore, the amount of B sufficient for one dialysis can be changed.
If the powder is put in a cartridge, it is not suitable for use in a dialysate adjusting device for a large number of people.

Further, although the liquid B (concentrated liquid) easily liberates CO ₂ , in the above-mentioned proposed system, the degassing means for CO ₂ generated on the downstream side of the filter is not taken into consideration. However, the CO ₂ generated on the downstream side of the filter flows through the flow rate control means together with the B concentrated liquid, which causes trouble in the concentration control. In particular, when a large bubble flows through the flow rate control means, the problem is great.

Therefore, an object of the present invention is to supply sodium bicarbonate powder and water in a dissolution tank to prepare a sodium bicarbonate solution B having a required concentration, and dilute the sodium bicarbonate solution at any time to give a predetermined concentration. By obtaining a concentrated sodium bicarbonate solution, it is possible to supply a large amount of sodium bicarbonate solution with a small-sized facility, and it is possible to easily achieve the additional preparation of the sodium bicarbonate solution in the dissolution tank even during dialysis. It is to provide a bicarbonate dialysate adjusting device for a large number of people.

[0020]

The bicarbonate dialysate preparation apparatus for multi-persons according to the present invention introduces sodium bicarbonate powder and water, stirs and mixes them, and passes them through a filter to a chamber of a required concentration. A dissolution tank configured to obtain a sodium bicarbonate solution, a water supply means having a control valve in communication with the dissolution tank, and a sodium bicarbonate solution for extracting the sodium bicarbonate solution in communication with the compartment of the dissolution tank It is characterized by comprising a take-out means and a dialysate adjusting means which is connected in communication with the sodium bicarbonate liquid take-out means.

In this case, the dialysate adjusting means is provided with a sodium bicarbonate liquid control means and a concentration measuring means in the sodium bicarbonate liquid taking out means, and the sodium bicarbonate liquid taking out means measures the concentration by the concentration measuring means. Combined with a water supply means having a water control means for adjusting the concentration of the sodium bicarbonate solution according to the value, and further combined with a means for supplying a dialysate containing no sodium bicarbonate solution to adjust the dialysate,
It can be configured to store a predetermined amount of the obtained dialysate in a storage tank.

The dialysate adjusting means includes a predetermined amount of dialysate containing no sodium bicarbonate, a predetermined amount of sodium bicarbonate solution supplied from the sodium bicarbonate solution extracting means, and a predetermined amount of water supplied from the water supply means. And are introduced into the mixing tank,
It is also possible to adjust the dialysate and store a predetermined amount of the obtained dialysate in the storage tank.

On the other hand, the dissolution tank defines a compartment at the bottom thereof for obtaining a sodium bicarbonate solution of a required concentration through a filter, a stirring means is provided above the filter, and an upper limit level is set above the stirring means. And a lower limit level setting device may be provided.

The stirring means can be constituted by means for rotating the screw, transmitting ultrasonic waves, and circulating the liquid by a pump.

Further, a water supply means equipped with a control valve is connected in communication with a dissolution tank defining a compartment for obtaining a sodium bicarbonate solution of a required concentration through a filter,
Further, a branch water supply means may be provided to connect the compartment and the discharge means as a stirring means arranged above the filter via a pump.

[0026]

According to the apparatus for adjusting a bicarbonate dialysate solution for a large number of people according to the present invention, the B powder is continuously dissolved in water, and the sodium bicarbonate solution thus obtained (hereinafter referred to as solution B).
Is supplied to the dialysate adjusting means, and is diluted with water by the dialysate adjusting means to obtain a sodium bicarbonate solution having a predetermined concentration, and mixed with a dialysate containing no sodium bicarbonate (hereinafter referred to as solution A), It is possible to prepare a dialysate having a predetermined mixing ratio.

Further, according to the present invention, a large amount of B powder can be dissolved over a long period of time by additionally adding B powder to the dissolution tank at any time, and the B liquid can be smoothly supplied to at least one dialysate adjusting means. The supply of the dialysate can be smoothly adjusted.

Further, before starting the dialysis, it is not necessary to measure the B end corresponding to the B solution which is expected to be consumed during the dialysis, and an appropriate amount can be added, and the B end at any time during the dialysis can be added. Additional input is possible.

Therefore, according to the present invention, the structure and operation are simplified, and the size and amount of the B solution are small, as compared with the structure in which the dissolution of the B powder and the adjustment of the B solution are repeated by the batch system. Supply is possible.

[0030]

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Next, an embodiment of a bicarbonate dialysate adjusting device for a large number of people according to the present invention will be described in detail below with reference to the accompanying drawings.

Embodiment 1 FIG. 1 is a schematic system diagram showing an embodiment of the device of the present invention. In FIG. 1, reference numeral 10 indicates a dissolution tank, and B powder (PB) in which only sodium bicarbonate (NaHCO ₃ ) is powder-formulated and water (W) are supplied to the dissolution tank 10.
In this case, an appropriate amount of B powder (PB) is introduced through the opening 12. An opening / closing lid is usually provided in this opening.
Water (W) is introduced via a control valve 18 by a water supply line 16 communicating with a water supply source 14 such as an RO unit, and when the water level reaches a predetermined level of the dissolution tank 10, an upper limit level detector 20a. This state is detected by the control valve 18 by the detecting operation of the upper limit level detector 20a.
To close the water supply. Although the temperature of water used in this case is 10 ° C., it is possible to obtain the liquid B having a required concentration by sufficient stirring. However, in order to facilitate the dissolution rate or control, it is 20 to 30 as in the conventional case. A water temperature of ° C is preferred.

Further, the dissolving tank 10 is provided with stirring means 22, and by operating this stirring means 22, the dissolution of the B powder supplied to the dissolving tank 10 is promoted. As the stirring means 22, a means utilizing rotation of a screw, transmission of ultrasonic waves, liquid circulation by a pump, or the like can be used.

However, the dialysis agent AF currently in circulation.
When observing the B powder of -2P (manufactured by Fuso Yakuhin Co., Ltd.) with an electron microscope, many particles having a size of 100 μm or less are included. Therefore, in the dissolution tank 10, the filter 2 which does not pass these B powders to the extent that there is no practical problem.
4 is properly selected and provided. Therefore, this filter 24
Does not have a large opening, and when water is supplied from above the filter 24, the air in the compartment 26 defined by the filter 24 can hardly escape.

Therefore, an exhaust line 30 provided with a degassing means 28 is provided outside the dissolution tank 10 so that the compartment 26 communicates with a position above a predetermined water level.
As the degassing means 28, an electromagnetic control valve, a pump or the like is usually used.
It is preferable to let the air inside escape. Therefore,
For example, by operating the stirring means 22 and then operating the degassing means 28, air is released from the exhaust line 30 and the liquid B flows into the compartment 26.

The B liquid thus retained in the compartment 26 is appropriately dialyzed by the dialysate adjusting means 4 via the B liquid extraction line 32.
It is configured to deliver liquid to 0. In this case, when the B concentrated liquid is taken out from the compartment 26, the agitating means 22 is appropriately operated to allow the B liquid to pass through the filter 24.
The concentrated liquid is supplied to the compartment 26.

When the solution B is consumed in the dialysate adjusting means 40 and the solution B retained in the compartment 26 of the dissolution tank 10 is taken out, and the water level in the dissolution tank 10 drops to the level set by the lower limit level detector 20b. Is the lower limit level detector 20
Under the action of b, the control valve 18 is opened and water is supplied from the water supply line 16 into the dissolution tank 10. Next, when the water level in the dissolution tank 10 rises to the set level of the upper limit level detector 20a, the control valve 18 is closed under the action of the upper limit level detector 20a to complete the water supply.

When the B powder is sufficiently present in the dissolution tank 10 and the dissolution of the B powder is promoted by stirring, the B liquid fed to the dialysate adjusting means 40 is a concentrated liquid having a substantially saturated concentration.
However, it is not necessary to feed the dialysate adjusting means 40 as a solution B having a substantially saturated concentration.
Within the range that does not interfere with adjusting the normal concentration of dialysate,
It can be delivered as a liquid B having a low concentration.

The liquid B is liable to liberate CO _2, and as the large amount of B powder is dissolved and the B concentrated liquid is consumed, CO ₂ is accumulated in the compartment 26, and as a result, CO ₂ becomes large bubbles and is taken out. It will flow out to the line 32 and will hinder the adjustment of the B liquid. Therefore, in this embodiment, the degassing means 28 is appropriately used.
Actuating the, escape of CO ₂ compartments 26 to the outside of the dissolution tank 10, and the B liquid extraction line 32 as a large amount of CO ₂ does not flow out.

Although the B end in the dissolution tank 10 decreases as the B solution is consumed, by adding the B end to the dissolution tank 10 at any time, a large amount of the B solution can be continuously supplied for a long time. Adjustment and supply can be performed. In addition, the dissolution tank 10
It is also possible to perform the B end charging into the B feeder, but it is also possible to manually perform the B end charging operation by hand.

That is, in this embodiment, the dissolution tank 1
The B end to be put into 0 does not need to be metered in particular and can be additionally added during dialysis. Therefore, the B end addition work is not a troublesome work, and this work is performed manually. There is no problem.

As described above, the solution B is sent to the dialysate adjusting means 40 via the solution B take-out line 32.
Further, the water is supplied through a water supply line 34 communicating with the water supply source 14. Then, the dialysate adjusting means 40 adjusts the dialysate for a large number of patients. The configuration of the dialysate adjusting means 40 will be described later.

Embodiment 2 FIG. 2 is a schematic system diagram showing another embodiment of the device of the present invention. In FIG. 2, for convenience of description, the same components as those in the embodiment shown in FIG. 1 are designated by the same reference numerals, and detailed description thereof will be omitted.

That is, in the embodiment shown in FIG.
Water is supplied to the dissolution tank 10 by a water supply line 16 which is connected to a compartment 26 at the bottom defined by a filter 24 through a control valve 18. In this case, a branch water supply line 36 is communicatively connected to the compartment 26, the tip of the branch water supply line 36 is branched into two, and one branch flow path 38a is provided above the compartment 26 (for example, the filter 2).
4) and the other branch flow path 38b.
Is located in the lower portion (eg, the bottom portion) of the compartment 26. Further, the dissolution tank 10 is provided with an upper limit level detector 20a and a lower limit level detector 20b, and water is supplied to the set level by the water supply line 16.

The branch water supply line 36 is connected to a liquid feed pump 42 to form a discharge line 44, and the discharge line 44 is put on the upper side of the filter 24 of the dissolution tank 10 at the end of B (PB). It is connected and arranged so as to communicate with the discharge means 46 embedded in.

In the present embodiment, the B end (PB) in the dissolution tank 10 is melted by driving the pump 42 provided in the discharge line 44 so that the branch flow passages 38a and 38b of the branch water supply line 36 are melted. The liquid in the compartment 26 is sucked in from the discharge chamber 46, and is discharged from the discharge means 46 through the discharge line 44.

However, the specific structure of the discharge means 90 is as shown in FIG. In FIG. 5, the discharge means 46 arranges the discharge pipe 48 forming the tip of the discharge line 44 while supporting the central portion of the filter 24, and forms the liquid collecting chamber 50 on the outer periphery of the inserted tip. Then, the rotor 52 is rotatably mounted. Further, on the outer peripheral portion of the rotor 52, injection pipes 54, 54 extending radially with the discharge pipe 48 as a center are symmetrically connected and arranged. Incidentally, reference numeral 51 indicates a through hole provided in the discharge pipe 48 for communicating with the liquid collecting chamber 50, and 53.
Indicates a stopper for preventing the rotor 52 from falling off, and 55 indicates an injection hole provided in the injection pipe 54.

In the discharge means 46 thus constructed, the liquid whose pressure has been increased by the drive of the pump 42 flows into the liquid collecting chamber 50 of the rotor 52 through the through hole 51 provided in the discharge pipe 48, and further the jet vip 54. B in the melting tank 10 from the ejection hole 55 of
Dissolution of the B powder is promoted by ejecting the liquid toward the powder (PB).

In this case, the injection holes 55 are arranged so that the rotor 52 is rotated by the reaction force of the jet flow when the amount of B powder in the dissolution tank 10 is reduced and the resistance against the jet of the liquid is reduced. At the same time, it is preferable that the injection hole 55 is provided obliquely downward so that the liquid is smoothly ejected toward the B end remaining on the filter 24.

The solution B obtained by dissolving the B powder passes through the filter 24 and flows into the compartment 26. As a result,
The liquid B is circulated in the dissolution tank 10 by driving the pump 42, and the water in the compartment 26 at the start of the operation is
It will be replaced with liquid.

The solution B thus obtained is appropriately sent to the dialysate adjusting means 40 through the solution B take-out line 32, as in the above-mentioned embodiment.

When the liquid level in the dissolution tank 10 drops to the level set by the lower limit level detector 20b due to the consumption of the liquid B, the control valve 18 is opened to start the water supply from the water supply line 16 to dissolve the liquid. The liquid level in the tank 10 is the upper limit level detector 20.
When the set level of a is reached, the control valve 18 is closed and the additional water supply is stopped.

When the pump 42 is driven, the one branch flow passage 38a on the suction side is provided in the dissolution tank 1 of the B liquid extraction line 32.
At a position higher than the opening to 0, it is opened near the filter 24, and the other branch flow path 38b is provided in the dissolution tank 10
Attached to the bottom of. Therefore, by driving the pump 42, the liquid is sucked from both the upper portion and the lower portion of the chamber 26, and most of the CO ₂ generated in the chamber 26 is sucked into the discharge line 44. A large amount of CO ₂ does not flow into the B liquid extraction line 32.

That is, by opening one branch flow passage 38a on the suction side of the pump 42 to the upper part of the compartment 26, the functions of the stirring means 22 and the degassing means 28 described in the embodiment of FIG. The pump 42 of the table can be used in common.

According to the B-end melting means constituted by the melting tank 10 in the above-mentioned embodiment, B charged into the melting tank 10 is B.
Since it is not necessary to specifically measure the powder amount, it is not a troublesome work, and the B powder can be additionally added at any time during dialysis. Further, since the liquid B can be supplied as a concentrated liquid, the dissolution tank 10 Can be made small.

Further, in the present embodiment, the B powder is not dissolved by the batch method, but the B powder is dissolved and the B liquid is always prepared in the dissolution tank 10 during dialysis, and the B liquid can be appropriately supplied. Therefore, not only a complicated structure and operation are not required, but also a large storage tank for storing the solution B other than the dissolution tank 10 is not required, so that it can be constructed in a small size and a large amount of B It is possible to supply liquid.

Next, the structure of the dialysate adjusting means 40 in the above-described first and second embodiments will be described.

FIG. 3 and FIG. 4 are system diagrams showing a schematic configuration of the dialysate adjusting means 40. Although not shown, these dialysate adjusting means 40 have a function provided in a conventional dialysate adjusting apparatus for a large number of people, such as a heating means,
Needless to say, the concentration measuring means, the degassing means, the pump, etc. can be appropriately additionally set.

Dialysate Adjusting Means (No. 1) First, in the dialysate adjusting means 40 shown in FIG. 3, the B solution take-out line 32 introduced from the outside, the B solution controlling means 60 including a metering pump, and the electric conductivity. A B liquid concentration measuring unit 62 including a meter is provided, and the B liquid controlling unit 60 is driven to drive the compartment 26 (see FIGS. 1 and 2).
The B liquid is led out to the B liquid extraction line 32, and the concentration of the B liquid is measured by the B liquid concentration measuring means 62. On the other hand, the water supply line 34 introduced from the outside is provided with water control means 64 such as a metering pump, and the B liquid extraction line 32 downstream of the B liquid concentration measuring means 62 is connected and arranged downstream thereof.

Therefore, at the confluence point 35 of the water supply line 34 and the B liquid take-out line 32, the B liquid control means 60 and the B liquid control means 60 are sequentially operated according to the concentration of the B liquid measured by the B liquid concentration measuring means 62. Water control means 6 as required
4. The B liquid flow rate from the B liquid extraction line 32 and the water supply flow rate from the water supply line 34 are adjusted as necessary.

Further, downstream of the water supply line 34, an A liquid supply line 68 for supplying the A liquid via the A liquid control means 66 is connected and arranged. Therefore, the water supply line 3
At the confluence point 37 between the liquid No. 4 and the liquid A supply line 68, the liquid A is injected into the mixed liquid of water and the liquid B to adjust the dialysate.

The dialysate thus prepared is introduced and stored in the storage tank 70. The storage tank 70 is provided with an upper limit level detector 71a and a lower limit level detector 71b so that a required amount of dialysate is always stored and sent to each dialyzer through the discharge flow path 72. In this case, the supply flow rate of the dialysate to each dialyzer changes depending on the number of patients undergoing dialysis treatment.

The storage tank 70 is normally opened to the atmosphere via an air filter (not shown), and when the liquid level in the storage tank 70 drops to the position of the lower limit level detector 71b, the dialysate adjustment operation is started. Then, when the liquid level rises to the set level of the upper limit level detector 71b, the adjustment operation of the dialysate is stopped. Therefore, the dialysate is adjusted intermittently during dialysis.

Further, in this embodiment, the water supply line 34
As the water control means 64 provided in, it is possible to use the one configured as shown in FIG. 6, for example. in this case,
The water flow rate often changes during the adjustment of the dialysate due to changes in the pressure of the water supply from the water supply source 14 (see FIGS. 1 and 2).

However, in FIG. 6, the water control means 64
Has a piston 82, which reciprocates in the cylinder 80, inserted through the piston 82. The piston 82 and the piston rod 84,
Seals 83, 85, and 85 are provided in the insertion portions of the cylinder 84 of the cylinder 84, and liquid-tight pump chambers 86 and 88 are provided inside the cylinder 80 on both sides of the piston 82.
Is configured. Then, with respect to the flow passages 90 and 92 communicating with these pump chambers 86 and 88, they are connected to the water supply line 34 through control valves 91a and 93b and 93a and 91b on the upstream side and the downstream side, respectively.

The water control means 64 constructed in this way is
First, in the state shown in FIG. 6, when the control valves 91a and 91b are opened, the piston 60 moves to the right due to the pressure of the water supply, and the water flows from the flow passage 90 into the pump chamber 86 via the control valve 91a. On the other hand, the water in the pump chamber 88 is sent from the flow path 92 to the downstream side of the water supply line 34 via the control valve 91b. Next, when the control valves 91a and 91b are closed and the control valves 93a and 93b are opened, the piston 60 moves to the left and the water in the pump chamber 86 flows from the flow passage 90 through the control valve 93b to the downstream of the water supply line 34. Is sent to the side. Therefore, the control valves 91a, 91b and 93a,
By appropriately opening and closing 93b, water can be continuously supplied to the water supply line 34.

In this case, the value of the water flow rate can be sequentially calculated by providing the piston speed measuring means 94 and measuring the piston speed. And
The speeds at which the B liquid control means 60 and the A liquid control means 66 shown in FIG. 3 should be operated can be sequentially controlled by the value of the water flow rate.

Next, the dialysate adjusting means 4 having the above construction.
The operation of 0 will be described. The B liquid produced by the B powder dissolving means shown in FIGS. 1 and 2 is the B liquid extraction line 32.
However, the concentration of this liquid B changes. Also A
The liquid is supplied after being adjusted to a predetermined concentration.

Therefore, the concentration of the B liquid is measured by the B liquid concentration measuring means 62, and the measured concentration value (and the water flow rate) is obtained.
Accordingly, the operating speeds of the B solution control means 60 and the A solution control means 66 are adjusted so that a dialysate having a predetermined concentration can be obtained. However, while the concentration of liquid B is being stably supplied, the mixing ratio of water, liquid B and liquid A does not change.
When the concentration of the liquid changes, the B liquid control means 60 is controlled in accordance with the change in the concentration measurement value of the B liquid, and
The liquid control means 66 is also controlled to change the respective flow rates of the B solution and the A solution flowing through the B solution extraction line 32 and the A solution supply line 68 so that the dialysate has a predetermined concentration with respect to the water flow rate.

Dialysate Adjusting Means (Part 2) FIG. 4 shows another embodiment of the dialysate adjusting means. For convenience of explanation, the same components as those of the embodiment shown in FIG. 3 will be described with the same reference numerals.

That is, in the embodiment shown in FIG.
The liquid B supplied from the liquid extraction line 32 and the liquid A supplied from the liquid A supply line 66 are introduced into the mixing tank 74.
In this case, the liquid A may be configured to be supplied to the mixing tank 74 after a predetermined amount is measured in a measuring tank (not shown) in advance. A water supply line 64 is connected to the mixing tank 74 via a control valve 62 to supply water. Thus, when the liquid level in the mixing tank 74 reaches the level set by the level detector 75,
The control valve 62 is closed to stop the water supply. Therefore, in this case, the dialysate for the volume set by the level detector 75 of the mixing tank 74 is adjusted by adjusting the dialysate once.

In the present embodiment, however, the B liquid extraction line 32 is provided with the B liquid concentration measuring means 62. Therefore, the concentration of the B liquid supplied from the B-end dissolving means (see FIGS. 1 and 2) changes, but in this case, in order to adjust the dialysate having a predetermined concentration each time the dialysate is adjusted, It may be set so that the amount of sodium bicarbonate dissolved in the supplied liquid B is constant.

Therefore, the time required to supply the solution B is a constant time T for each adjustment of the dialysate. During this time T, B
The B liquid control unit 60 is sequentially controlled according to the measurement value of the liquid concentration measuring unit 62, and is operated so that the amount of sodium bicarbonate contained in the B liquid supplied during the unit time ΔT becomes constant. . That is, it is possible to know in advance how much sodium bicarbonate is contained in the B solution with respect to the B solution concentration measured value (for example, the electric conductivity), and the B solution control means is provided corresponding to the concentration measured value. The control data of 60 can be stored in the device in advance. In this way, by using the control data according to the concentration measurement value by the B liquid concentration measuring means 62, the B liquid controlling means 60 can be controlled with almost no time delay.

A circulation passage 77 provided with a pump 76 is provided outside the mixing tank 74, and the dialysate concentration is measured while stirring the liquid in the mixing tank 74. Then, if it is confirmed that the dialysate concentration is normal, the dialysate is transferred to and stored in the dialysate storage tank 70 through the discharge passage 72 which is led out from a part of the circulation passage 77 through the control valve 78. The stored dialysate can be appropriately supplied to a dialyzer for a large number of people.

Although the preferred embodiments of the present invention have been described above, the present invention is not limited to the above-described embodiments, and various design changes can be made without departing from the spirit of the present invention. Of course.

For example, in the embodiment shown in FIG. 1 and FIG. 2, the B liquid take-out line 32 is branched so that the B liquid is supplied from the B powder dissolving means to the plurality of dialysate adjusting means 40. be able to.

Further, when the B-end dissolving means and the dialysate adjusting means 40 are constructed as separate units as in the conventional case, both units are not necessarily arranged close to each other in the dialysis facility, and therefore, if necessary. Therefore, it is preferable to provide a pump means or perform a heat treatment on the B liquid extraction line 32 shown in FIGS. 1 and 2.

Further, for the purpose of supplying clean B liquid, it is easy to add a cleaning and disinfecting function, install a sterilizing lamp, install a filter for sterilization, etc. to the B powder dissolving means of the present invention. can do.

The B powder can be charged into the melting tank 10 by using a powder feeder or the like, but it is also possible to manually perform the B powder charging operation manually. That is, B to be input
It is not necessary to weigh the end powder, and since it can be added during dialysis, the end work of B end is not a troublesome work, and there is no obstacle to performing this work manually. Absent. Further, in this case, it is preferable to be configured to have a function of notifying that it is necessary to additionally add the B end.

That is, when the B end in the dissolution tank 10 is low, the additional water supply results in the dialysate adjusting means 40.
The concentration of the B liquid sent to is decreased. As a result, the measured value of the B liquid concentration measuring means 62 decreases. When the measured value becomes lower than a set concentration (usually, a low concentration within the range that does not hinder the adjustment of dialysate), a buzzer or an alarm means having a display function is used to notify. In this case, the additional water supply may not be performed. By this alarm notification, it is only necessary to manually insert the B-end, if necessary.

Further, the B powder dissolving means may be provided with another B liquid concentration measuring means as appropriate, and the notification may be given by the measured value of the B liquid concentration measuring means.

In this way, in the B-end dissolving means in the present invention, a large amount of B-solution is supplied to the dialysate adjusting means 40 for a long time by additionally adding B-end into the dissolution tank 10 as needed. It is possible to smoothly adjust the liquid.

In the embodiment of the dialysate adjusting means shown in FIG. 3 and FIG. 4, the case where the solution A adjusted to a predetermined concentration is supplied has been described, but the case where the solution A concentration also changes is described below. You can also operate like.

For example, when powder (or granules) (A powder) is dissolved as the agent A in the dialysis equipment to form the solution A, the agent A has a composition mainly containing a plurality of electrolyte compounds. Therefore, to adjust the A liquid, add a predetermined amount of A to a predetermined amount of water.
It is usually done by dissolving the powder. The concentration may not always reach the predetermined level each time the solution A is adjusted due to an incorrect measurement of water or the end of A.

On the other hand, when the concentration of the A liquid changes, the A liquid concentration measuring means is appropriately provided in the A liquid supply line 68 shown in FIGS. 3 and 4. Then, according to the change in the measured value by the A liquid concentration measuring means and the change in the B liquid concentration measured value,
Sequential solution B control means 60 so that the dialysate has a predetermined concentration
And the A liquid control means 66 may be controlled.

[0085]

As is apparent from the above-described embodiments, according to the present invention, sodium bicarbonate powder and water are introduced, and these are stirred and mixed, and the concentrated sodium bicarbonate solution is added to the compartment through the filter. A dissolution tank configured to obtain, a water supply means having a control valve communicating with the dissolution tank, a sodium bicarbonate solution extraction means for communicating with the compartment of the dissolution tank to remove the sodium bicarbonate solution, and By comprising a sodium bicarbonate solution extracting means and a dialysate adjusting means connected in communication with the sodium bicarbonate solution extracting means, sodium bicarbonate powder and water are supplied in the dissolution tank to prepare a sodium bicarbonate solution having a required concentration. By diluting the sodium solution at any time to obtain a sodium bicarbonate solution of a predetermined concentration, it is possible to supply a large amount of sodium bicarbonate solution with a small facility,
Moreover, it is possible to obtain a bicarbonate dialysate preparation device for a large number of people, which can easily achieve the additional preparation of the sodium bicarbonate solution in the dissolution tank even during dialysis.

According to the apparatus for adjusting a bicarbonate dialysate solution for a large number of people of the present invention, by adding B powder to the dissolution tank at any time,
It is possible to dissolve a large amount of B powder for a long time, adjust the B solution, and smoothly supply the B solution to at least one dialysate adjusting device.

Further, before starting dialysis, it is not necessary to measure the B end corresponding to the B solution which is expected to be consumed during the dialysis, and an appropriate amount can be added, and the B end can be added at any time during the dialysis. Additional input is possible.

Therefore, in the apparatus of the present invention, manually inserting the B powder into the dissolution tank is not a troublesome work, and since the proportion of the solution B is small, the solution B can be supplied to the conventional multi-person dialysate supply apparatus. As compared with the B-end melting means for supplying B, it can be constructed in a small size, and its adjustment work can be easily achieved. That is, in the dissolution tank, the solution B is not adjusted, but the inside of the dissolution tank is configured to have the B end and the solution B having a required concentration during dialysis, and the solution B always prepared in the dissolution tank is used at any time. Since the liquid B having a predetermined concentration can be diluted and adjusted, a large storage tank for storing the liquid B is not required, and a small amount of liquid B can be supplied.

The apparatus of the present invention has a simpler structure and operation as compared with a structure in which dissolution of B powder and adjustment of solution B are repeated by a batch system, and a small size and a large amount of dialysate can be supplied. Has the advantage that

[Brief description of drawings]

FIG. 1 is a schematic system diagram showing an embodiment of a bicarbonate dialysate adjusting device for a large number of people according to the present invention.

FIG. 2 is a schematic system diagram showing another embodiment of a bicarbonate dialysate preparation device for a large number of people according to the present invention.

FIG. 3 is a schematic system diagram showing an embodiment of dialysate adjusting means applied to a bicarbonate dialysate adjusting device for a large number of people according to the present invention.

FIG. 4 is a schematic system diagram showing another embodiment of the dialysate adjusting means applied to the bicarbonate dialysate adjusting device for multiple persons according to the present invention.

5 is an enlarged cross-sectional view of an essential part showing a configuration example of discharge means in the multi-body bicarbonate dialysis solution adjusting apparatus shown in FIG.

FIG. 6 is an enlarged cross-sectional explanatory view of an essential part showing a configuration example of a water control means in the dialysate adjusting means shown in FIG.

[Explanation of symbols]

 10 dissolution tank 12 opening 14 water supply source 16 water supply line 18 control valve 20a upper limit level detector 20b lower limit level detector 22 agitation means 24 filter 26 compartment 28 degassing means 30 exhaust line 32 liquid extraction line 34 water supply line 35 confluence point 36 Branch water supply line 37 Confluence point 38a Upper limit level detector 38b Lower limit level detector 39 Control valve 40 Dialysate adjusting means 42 Pump 44 Discharge line 46 Discharge means 48 Discharge pipe 50 Liquid collection chamber 51 Through hole 52 Rotor 53 Stopper 54 Injection pipe 55 Injection hole 60 B liquid control means 62 Concentration measuring means 64 Water control means 66 A liquid control means 68 A liquid supply line 70 Storage tank 71a Upper limit level detector 71b Lower limit level detector 72 Discharge passage 74 Mixing tank 75 Level detector 76 Pump 77 Circulation flow path 78 Control The valve 80 the cylinder 82 piston 83 seal 84 the piston rod 85 seals 86, 88 the pump chamber 90, 92 the channel 91a, 91b control valve 93a, 93 b control valve 94 piston speed measuring means

Claims (6)

[Claims] 1. A dissolution tank configured to introduce sodium bicarbonate powder and water, stir and mix these, and obtain a sodium bicarbonate solution of a required concentration in a compartment through a filter,
A water supply means provided with a control valve that is connected to the dissolution tank for communication,
It is characterized by comprising sodium bicarbonate liquid extraction means for communicating with the compartment of the dissolution tank to extract the sodium bicarbonate liquid, and dialysate adjusting means connected in communication with the sodium bicarbonate liquid extraction means. Bicarbonate dialysate adjustment device for the number of people. 2. The dialysate adjusting means is provided with a sodium bicarbonate solution control means and a concentration measuring means in the sodium bicarbonate solution taking out means, and the sodium bicarbonate solution taking out means is provided with the concentration measured value by the concentration measuring means. The concentration of the sodium bicarbonate solution is adjusted according to the water supply means provided with a water control means, and further a means for supplying a dialysate solution containing no sodium bicarbonate solution is combined to adjust the dialysate solution. The multi-body bicarbonate dialysate preparation device according to claim 1, wherein a predetermined amount of the dialysate is stored in a storage tank. 3. The dialysate adjusting means comprises a predetermined amount of dialysate containing no sodium bicarbonate, and a predetermined amount of sodium bicarbonate solution supplied from the sodium bicarbonate solution extracting means and water supplied from the water supply means. 2. The apparatus for preparing a bicarbonate dialysate solution for a large number of people according to claim 1, which is configured so that and are introduced into a mixing tank to adjust the dialysate and a predetermined amount of the obtained dialysate is stored in a storage tank. 4. The dissolution tank defines a compartment at its bottom for obtaining a sodium bicarbonate solution of a required concentration through a filter, a stirring means is provided above the filter, and an upper limit level is set above the stirring means. 2. The apparatus for adjusting a bicarbonate dialysate for a large number of people according to claim 1, wherein the apparatus and a lower limit level setting device are provided. 5. The stirring means comprises means for rotating a screw, transmitting ultrasonic waves, and circulating a liquid by a pump.
Bicarbonic acid bicarbonate dialysate adjustment device for the multi-user described. 6. A dissolution tank defining a compartment for obtaining a sodium bicarbonate solution having a required concentration through a filter is connected to a water supply means having a control valve in the compartment, and the compartment and a pump. 2. A multi-body bicarbonate dialysate adjusting device for a multi-person according to claim 1, further comprising: a branch water supply means for connecting and communicating with a discharge means as a stirring means arranged above the filter via a water supply means.