JPH0826998A - 哺乳類における肺細気管支漏出を軽減する方法 - Google Patents
哺乳類における肺細気管支漏出を軽減する方法Info
- Publication number
- JPH0826998A JPH0826998A JP7186592A JP18659295A JPH0826998A JP H0826998 A JPH0826998 A JP H0826998A JP 7186592 A JP7186592 A JP 7186592A JP 18659295 A JP18659295 A JP 18659295A JP H0826998 A JPH0826998 A JP H0826998A
- Authority
- JP
- Japan
- Prior art keywords
- methotrexate
- administration
- interleukin
- dose
- leakage
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2013—IL-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US269702 | 1994-07-01 | ||
| US08/269,702 US5593671A (en) | 1994-07-01 | 1994-07-01 | Method of attenuating lung capillary leak in a mammal |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH0826998A true JPH0826998A (ja) | 1996-01-30 |
Family
ID=23028336
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP7186592A Pending JPH0826998A (ja) | 1994-07-01 | 1995-06-30 | 哺乳類における肺細気管支漏出を軽減する方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5593671A (enExample) |
| EP (1) | EP0692251A1 (enExample) |
| JP (1) | JPH0826998A (enExample) |
| KR (1) | KR960003728A (enExample) |
| AU (1) | AU2335195A (enExample) |
| CA (1) | CA2152981A1 (enExample) |
| HU (1) | HUT74245A (enExample) |
| NZ (1) | NZ272476A (enExample) |
| TW (1) | TW294596B (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007527242A (ja) * | 2004-03-05 | 2007-09-27 | カイロン コーポレーション | 治療剤の患者耐容性を予測するためのインビトロ試験システム |
| JP2017533274A (ja) * | 2014-10-29 | 2017-11-09 | セラカインド リミテッドＴｈｅｒａｋｉｎｄ Ｌｔｄ | メトトレキサート製剤 |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1115397B1 (en) | 1998-08-28 | 2006-05-24 | Intarcia Therapeutics, Inc. | Compositions for mitigating the adverse effects of interleukin-2 |
| US6544504B1 (en) | 1999-07-28 | 2003-04-08 | Schering Corporation | Combined use of interleukin 10 and methotrexate for immuno-modulatory therapy |
| AU2001283191A1 (en) * | 2000-08-10 | 2002-02-25 | Uab Research Foundation | Compositions containing an inhibitor of dihydrofolate reductase and a folate |
| DE102006033837A1 (de) | 2006-07-21 | 2008-01-31 | Medac Gesellschaft für klinische Spezialpräparate m.b.H | Konzentrierte Methotrexat-Lösungen |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK86988A (da) * | 1987-02-25 | 1988-08-26 | Takeda Chemical Industries Ltd | Liposompraeparat og anvendelse deraf |
-
1994
- 1994-07-01 US US08/269,702 patent/US5593671A/en not_active Expired - Fee Related
-
1995
- 1995-06-29 TW TW084106704A patent/TW294596B/zh active
- 1995-06-29 AU AU23351/95A patent/AU2335195A/en not_active Abandoned
- 1995-06-29 CA CA002152981A patent/CA2152981A1/en not_active Abandoned
- 1995-06-29 EP EP95304590A patent/EP0692251A1/en not_active Withdrawn
- 1995-06-30 NZ NZ272476A patent/NZ272476A/en unknown
- 1995-06-30 HU HU9501980A patent/HUT74245A/hu unknown
- 1995-06-30 KR KR1019950019351A patent/KR960003728A/ko not_active Withdrawn
- 1995-06-30 JP JP7186592A patent/JPH0826998A/ja active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007527242A (ja) * | 2004-03-05 | 2007-09-27 | カイロン コーポレーション | 治療剤の患者耐容性を予測するためのインビトロ試験システム |
| JP2017533274A (ja) * | 2014-10-29 | 2017-11-09 | セラカインド リミテッドＴｈｅｒａｋｉｎｄ Ｌｔｄ | メトトレキサート製剤 |
| JP2021138748A (ja) * | 2014-10-29 | 2021-09-16 | セラカインド リミテッドTherakind Ltd | メトトレキサート製剤 |
| US11129833B2 (en) | 2014-10-29 | 2021-09-28 | Therakind Ltd. | Methotrexate formulation |
| US11771701B2 (en) | 2014-10-29 | 2023-10-03 | Therakind Ltd. | Methotrexate formulation |
Also Published As
| Publication number | Publication date |
|---|---|
| KR960003728A (ko) | 1996-02-23 |
| TW294596B (enExample) | 1997-01-01 |
| NZ272476A (en) | 1997-06-24 |
| HU9501980D0 (en) | 1995-08-28 |
| EP0692251A1 (en) | 1996-01-17 |
| AU2335195A (en) | 1996-01-18 |
| CA2152981A1 (en) | 1996-01-02 |
| HUT74245A (en) | 1996-11-28 |
| US5593671A (en) | 1997-01-14 |
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