JPH0753334A - Hair restoring and growing cosmetic - Google Patents
Hair restoring and growing cosmeticInfo
- Publication number
- JPH0753334A JPH0753334A JP22217693A JP22217693A JPH0753334A JP H0753334 A JPH0753334 A JP H0753334A JP 22217693 A JP22217693 A JP 22217693A JP 22217693 A JP22217693 A JP 22217693A JP H0753334 A JPH0753334 A JP H0753334A
- Authority
- JP
- Japan
- Prior art keywords
- hair
- growth
- cosmetic
- sodium
- alcohol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
Description
【０００１】[0001]
【産業上の利用分野】本発明は頭髪の発生及び成長を促
進させる頭髪発毛・育毛化粧料に関する。特に、本発明
は血行促進、酸化剤、毛根機能改善剤、殺菌消毒剤、保
湿剤を主成分とする頭髪発毛・育毛化粧料に関する。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a hair-growth / hair-growth cosmetic for promoting the growth and growth of hair. In particular, the present invention relates to a hair-growth / hair-growth cosmetic containing, as a main component, a blood circulation promoter, an oxidizing agent, a hair root function improving agent, a sterilizing / disinfecting agent, and a moisturizing agent.
【０００２】[0002]
【従来の技術】従来から、アラピーシア（局部脱毛を含
む脱毛症・禿頭症）の原因として様々な説が発表されて
いる。これらの説には、栄養摂取のアンバランス説、頭
皮の不潔説、ストレスの蓄積説、男性ホルモン過剰説、
頭形説、頭皮厚説が含まれている。2. Description of the Related Art Conventionally, various theories have been published as causes of Alapiacia (alopecia / baldness including local hair loss). These theories include nutritional imbalance theory, scalp filth theory, stress accumulation theory, androgen excess theory,
Includes head theory and scalp theory.
【０００３】ところが、これら原因がどのように作用し
て、アラピーシアを発症させるかの作用機序の解明が十
分ではなく、依然としてアラピーシアの場合、発毛は不
可能である。[0003] However, the mechanism of action of how these causes act to cause Alapissia is not fully elucidated, and in the case of Alapisia, hair growth is impossible.
【０００４】このような状況下において、近年生化学の
著しい進歩に伴い、頭髪に関する作用機序の研究も進
み、以下に述べる有力な学説が明らかにされている。Under these circumstances, along with the remarkable progress in biochemistry in recent years, research on the mechanism of action on hair has progressed, and the following powerful theories have been clarified.
【０００５】ａ）抹消血管血流促進説 頭部皮下組織、抹消血管の血流量が減少し、毛乳頭部位
置への血液供給不足により新陳代謝が低下し、この部位
に脱毛が生じるという説である。A) Peripheral blood vessel blood flow promotion theory It is a theory that blood flow in the subcutaneous tissue of the head and peripheral blood vessels is reduced, metabolism is reduced due to insufficient blood supply to the position of the papilla of the hair, and hair loss occurs at this site. .
【０００６】ｂ）毛根機能改善説 頭髪は、体内からの栄養を血管を通じて補給し、毛乳頭
中の毛母細胞からケラチン細胞へと細胞分裂を繰り返し
て成長していくが、何らかの原因で頭髪をつくる代謝機
能が低下またはストップし、この部位に脱毛を生じると
いう説である。B) The theory of improvement of hair root function Hair replenishes nutrients from the body through blood vessels and grows by repeating cell division from hair mother cells in the papilla to keratin cells. It is a theory that the metabolic function that builds up is reduced or stopped, causing hair loss at this site.
【０００７】ｃ）男性ホルモン説 頭髪に作用するホルモンはテストステロンと呼ばれる男
性ホルモンである。このテストステロンは皮脂腺及び毛
包部に存在し、還元作用をもつ酵素５α−リダクターゼ
により５α−ジヒドロテストステロン（以下５α−ＤＨ
Ｔと呼ぶ）に変化する。この５α−ＤＨＴが頭毛包にお
ける糖タンパクの合成に関与する代謝系を阻害して、機
能低下を起こして頭毛包を萎縮させるために、頭髪の成
長が続かないという説である。以上の各説については図
１及び図２〜図５にまとめてある。C) Male Hormone The hormone acting on hair is a male hormone called testosterone. This testosterone is present in the sebaceous glands and hair follicles, and is reduced by the enzyme 5α-reductase, which causes 5α-dihydrotestosterone (hereinafter referred to as 5α-DH).
(T). It is the theory that this 5α-DHT inhibits the metabolic system involved in the synthesis of glycoprotein in the hair follicle, causes a decline in function, and causes the hair follicle to atrophy, so that hair growth does not continue. The above theories are summarized in FIG. 1 and FIGS.
【０００８】[0008]
【発明が解決しようとする課題】本発明者は前記の有力
な３つの説に基づき研究を進めた結果、説ａ）について
は血流量を増加させる作用のある成分を、説ｂ）につい
ては毛根機能を改善する作用のある成分を、そして、説
ｃ）については還元作用により精製される５α−ＤＨＴ
をその前段階で還元させないような成分を直接頭皮を通
じて与えれば、頭皮に頭髪を回復できることが可能であ
ること見いだした。The present inventor has conducted research based on the above three strong theories, and as a result, for the theory a), a component having an action of increasing blood flow, and for the theory b) hair roots. 5α-DHT, which is purified by reducing action for components that improve the function, and for theory c)
It was found that it is possible to restore the hair to the scalp by directly giving a component that does not reduce the scalp to the scalp.
【０００９】また、アラピーシアは複雑な機序が重なっ
て、発症するだけでなく、個人差が大きい。従って、頭
髪発毛・育毛化粧料はそれらをカバーできる複数の成分
を配合する必要がある。[0009] Further, Alapiacia not only develops due to complicated complicated mechanisms, but also has large individual differences. Therefore, it is necessary to mix a plurality of components capable of covering the hair growth / hair growth cosmetics.
【００１０】[0010]
【課題を解決するための手段】すなわち、本発明はＬ−
メントール、ｐ−トルエンスルホニルクロルアミドナト
リウム、次亜塩素酸ナトリウム、Ｄ−パントテニルアル
コール及びそれらの溶剤からなる頭髪発毛・育毛化粧料
を提供するものである。That is, the present invention is an L-
The present invention provides a hair growth / hair growth cosmetic comprising menthol, sodium p-toluenesulfonyl chloride, sodium hypochlorite, D-pantothenyl alcohol and a solvent thereof.
【００１１】好ましくは、上記溶剤としてエチルアルコ
ール、多価アルコール、及び精製水を使用する。この多
価アルコールとしてはグリセリン、濃グリセリン、ジグ
リセリン、プロピレングリコール、ジプロピレングリコ
ール、１，３−ブチレングリコール、及びヘキシレング
リコールから選択される１種か、あるいは２種以上の混
合物が使用できる。Preferably, ethyl alcohol, polyhydric alcohol, and purified water are used as the solvent. As the polyhydric alcohol, one kind selected from glycerin, concentrated glycerin, diglycerin, propylene glycol, dipropylene glycol, 1,3-butylene glycol, and hexylene glycol, or a mixture of two or more kinds can be used.
【００１２】[0012]
【作用及び実施例】本発明者は、まづこれらの成分を組
み合わせ種々検討し、実験を行って、成分の相溶性、安
定性等のファクターについて調べた結果に基づき本発明
の頭髪発毛・育毛化粧料の一つを処方した。これを以下
に示すように、ボランティアの頭皮に直接かつ継続的に
投与した。ACTIONS AND EXAMPLES The present inventor first studied various combinations of these components, conducted experiments, and examined the factors such as compatibility and stability of the components, based on the results of hair growth of the present invention. One of the hair-growth cosmetics was prescribed. It was administered directly and continuously to the scalp of volunteers, as shown below.
【００１３】 処方例 成分 配合量、重量％ Ｌ−メントール ０．１〜０．２ Ｄ−パントテニルアルコール ０．１〜０．２ ｐ−トルエンスルホニルアミドナトリウム ０．０５〜０．１５ 次亜塩素酸ナトリウム ０．０５〜０．２ １，３−ブチレングリコール １．０〜２．０ エチルアルコール ２０．０〜３０．０ 精製水 残部 合計：１００重量％Prescription example Ingredients Amount, wt% L-menthol 0.1-0.2 D-pantothenyl alcohol 0.1-0.2 p-toluenesulfonylamide sodium 0.05-0.15 hypochlorous acid Sodium 0.05-0.2 1,3-butylene glycol 1.0-2.0 Ethyl alcohol 20.0-30.0 Purified water balance Total: 100% by weight
【００１４】Ｌ−メントールは血流量促進剤として、Ｄ
−パントテニルアルコールは毛根機能改善剤として、ｐ
−トルエンスルホニルアミドナトリウムは殺菌・消毒剤
として、次亜塩素酸ナトリウムは酸化剤として、多価ア
ルコール、即ち１，３−ブチレングリコールは頭皮保湿
剤として、そしてエチルアルコールは消毒剤及びこれら
の有機溶剤として作用する。L-menthol is used as a blood flow promoting agent, D
-Pantothenyl alcohol is used as a hair root function improving agent in p
-Sodium toluenesulfonylamide as a sterilizing and disinfecting agent, sodium hypochlorite as an oxidizing agent, polyhydric alcohols, i.e. 1,3-butylene glycol as a scalp moisturizing agent, and ethyl alcohol as a disinfecting agent and these organic solvents. Acts as.
【００１５】この水溶液は室温でエタノール相と水相に
分け、各成分を溶解後エタノール相と水相とを合わせ混
合して調合する。This aqueous solution is divided into an ethanol phase and an aqueous phase at room temperature, and after dissolving each component, the ethanol phase and the aqueous phase are combined and mixed to prepare.
【００１６】この水溶液の場合、頭皮に１日１〜３回塗
布・擦り込む。個人により相違するが、塗布量は約１２
０〜１８０ｃｃ／月である。In the case of this aqueous solution, it is applied and rubbed on the scalp 1 to 3 times a day. The application amount is about 12 depending on the individual.
It is 0 to 180 cc / month.
【００１７】若年性脱毛症のボランティア５０人（２０
〜３８才）に上記処方の化粧料を上記塗布量で塗布し
た。この結果、１日平均０．１〜０．３mmの硬毛の発毛
が認められた。頭頂脱毛の場合、約２〜３ヶ月の連続塗
布で全く目立たない状態にまで回復した。50 volunteers with alopecia areata (20
(About 38 years old) was applied with the above-mentioned amount of the above-mentioned cosmetics. As a result, hair growth of 0.1 to 0.3 mm on average per day was recognized. In the case of parietal hair loss, continuous application for about 2 to 3 months restored the condition to a completely inconspicuous state.
【００１８】[0018]
【発明の効果】以上の説明から明らかなように、本発明
によれば、Ｌ−メントール、ｐ−トルエンスルホニルク
ロルアミドナトリウム、次亜塩素酸ナトリウム、Ｄ−パ
ントテニルアルコール及びそれらの溶剤からなる頭髪発
毛・育毛化粧料を提供するもので、この化粧料は、頭皮
に塗布、擦り込むことによって血流量の増加、毛根機能
の改善、殺菌消毒によるフケ菌の増殖抑制（減少）、皮
脂腺及び毛包部における５α−ＤＨＴの生成の抑制、頭
皮の保湿機能の維持等により頭髪を回復できる作用効果
を有する。As is apparent from the above description, according to the present invention, hair comprising L-menthol, sodium p-toluenesulfonylchloramide, sodium hypochlorite, D-pantothenyl alcohol and their solvents. We provide hair-growth and hair-growth cosmetics, which are applied to the scalp and rubbed to increase blood flow, improve hair root function, and suppress (decrease) proliferation of dandruff bacteria by sterilizing and disinfecting, sebaceous glands and hair. It has the effect of being able to recover hair by suppressing the production of 5α-DHT in the wrapping part and maintaining the moisturizing function of the scalp.
【図１】毛の模式図である。FIG. 1 is a schematic view of hair.
【図２】本開示で説明した有力な学説ａ）の理解を助け
る図である。FIG. 2 is a diagram that aids in understanding the prevailing theory a) described in this disclosure.
【図３】本開示で説明した有力な学説ｂ）の理解を助け
る図である。FIG. 3 is a diagram that aids in understanding the prevailing theory b) described in this disclosure.
【図４】本開示で説明した有力な学説ｃ）の理解を助け
る図である。FIG. 4 is a diagram that aids in understanding the prevailing theory c) described in this disclosure.
【図５】本開示で説明した有力な学説ｃ）のテストステ
ロンの化学変化を示す化学構造図である。FIG. 5 is a chemical structure diagram showing a chemical change of testosterone according to the prevailing theory c) described in the present disclosure.
Claims (5)
ルクロルアミドナトリウム、次亜塩素酸ナトリウム、Ｄ
−パントテニルアルコール及びそれらの溶剤からなるこ
とを特徴とする頭髪発毛・育毛化粧料。1. L-menthol, sodium p-toluenesulfonyl chloride, sodium hypochlorite, D
-A hair growth and hair restoration cosmetic characterized by comprising pantothenyl alcohol and a solvent thereof.
コール、及び精製水から選択される請求項１記載の頭髪
発毛・育毛化粧料。2. The hair growth / hair growth cosmetic according to claim 1, wherein the solvent is selected from ethyl alcohol, polyhydric alcohol, and purified water.
リセリン、ジグリセリン、プロピレングリコール、ジプ
ロピレングリコール、１，３−ブチレングリコール、及
びヘキシレングリコールから選択される１種か、あるい
は２種以上の混合物である請求項２記載の頭髪発毛・育
毛化粧料。3. The polyhydric alcohol is one kind selected from glycerin, concentrated glycerin, diglycerin, propylene glycol, dipropylene glycol, 1,3-butylene glycol, and hexylene glycol, or a mixture of two or more kinds. The hair growth and hair restoration cosmetic composition according to claim 2, wherein
１８０ｃｃを塗布、擦り込む請求項１〜４のいずれかに
記載の頭髪発毛・育毛化粧料。5. A total of 120 to 3 times a day for 1 to 3 times a day.
The hair growth and hair restoration cosmetic according to any one of claims 1 to 4, wherein 180 cc is applied and rubbed.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP22217693A JPH0753334A (en) | 1993-08-13 | 1993-08-13 | Hair restoring and growing cosmetic |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP22217693A JPH0753334A (en) | 1993-08-13 | 1993-08-13 | Hair restoring and growing cosmetic |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH0753334A true JPH0753334A (en) | 1995-02-28 |
Family
ID=16778365
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP22217693A Pending JPH0753334A (en) | 1993-08-13 | 1993-08-13 | Hair restoring and growing cosmetic |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH0753334A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008510805A (en) * | 2004-08-25 | 2008-04-10 | モレキュラー リサーチ センター インコーポレイテッド | Cosmetic composition comprising certain cyclohexane mono-, di- or triol, or cyclohexylmethane, ethane or propanol |
| JP2008179599A (en) * | 2006-12-27 | 2008-08-07 | Nof Corp | Composition used for integumentary system tissue and comprising ingredient originated from plant in ericacees, ericaceae |
| JP2009209140A (en) * | 2008-02-07 | 2009-09-17 | Rohto Pharmaceut Co Ltd | Chlorite compound-containing aqueous composition containing menthol |
| WO2015129564A1 (en) * | 2014-02-27 | 2015-09-03 | 一般社団法人グリーンエバー | Composition for promoting hair growth and/or hair restoration containing sulfa agent and chitosan agent |
| WO2018158990A1 (en) * | 2017-03-02 | 2018-09-07 | 株式会社マンダム | Scalp care product |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5862107A (en) * | 1981-10-10 | 1983-04-13 | Yoshio Murai | Cosmetic for producing and growing hair |
| JPS63303914A (en) * | 1987-06-04 | 1988-12-12 | Kanebo Ltd | Hair nourishing cosmetic |
| JPH0314510A (en) * | 1989-04-24 | 1991-01-23 | Revlon Inc | Hair cultivating composition and use thereof |
-
1993
- 1993-08-13 JP JP22217693A patent/JPH0753334A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5862107A (en) * | 1981-10-10 | 1983-04-13 | Yoshio Murai | Cosmetic for producing and growing hair |
| JPS63303914A (en) * | 1987-06-04 | 1988-12-12 | Kanebo Ltd | Hair nourishing cosmetic |
| JPH0314510A (en) * | 1989-04-24 | 1991-01-23 | Revlon Inc | Hair cultivating composition and use thereof |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008510805A (en) * | 2004-08-25 | 2008-04-10 | モレキュラー リサーチ センター インコーポレイテッド | Cosmetic composition comprising certain cyclohexane mono-, di- or triol, or cyclohexylmethane, ethane or propanol |
| JP2008179599A (en) * | 2006-12-27 | 2008-08-07 | Nof Corp | Composition used for integumentary system tissue and comprising ingredient originated from plant in ericacees, ericaceae |
| JP2009209140A (en) * | 2008-02-07 | 2009-09-17 | Rohto Pharmaceut Co Ltd | Chlorite compound-containing aqueous composition containing menthol |
| WO2015129564A1 (en) * | 2014-02-27 | 2015-09-03 | 一般社団法人グリーンエバー | Composition for promoting hair growth and/or hair restoration containing sulfa agent and chitosan agent |
| WO2018158990A1 (en) * | 2017-03-02 | 2018-09-07 | 株式会社マンダム | Scalp care product |
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