JPH07506099A - 置換インドリジノ[1,2−b]キノリノン - Google Patents

置換インドリジノ[1,2−b]キノリノン

Info

Publication number
JPH07506099A
JPH07506099A JP5518629A JP51862993A JPH07506099A JP H07506099 A JPH07506099 A JP H07506099A JP 5518629 A JP5518629 A JP 5518629A JP 51862993 A JP51862993 A JP 51862993A JP H07506099 A JPH07506099 A JP H07506099A
Authority
JP
Japan
Prior art keywords
compound
formula
oxy
methyl
propyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP5518629A
Other languages
English (en)
Japanese (ja)
Inventor
バージズ,デイビッド・アラン
ヘルツベルク,ロバート・フィリップ
ジョンソン,ランドール・キース
キングスベリー,ウィリアム・デニス
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Priority claimed from PCT/US1993/003596 external-priority patent/WO1993020818A1/en
Publication of JPH07506099A publication Critical patent/JPH07506099A/ja
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP5518629A 1992-04-17 1993-04-15 置換インドリジノ[1,2−b]キノリノン Pending JPH07506099A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87064992A 1992-04-17 1992-04-17
US870,649 1992-04-17
PCT/US1993/003596 WO1993020818A1 (en) 1990-10-31 1993-04-15 SUBSTITUTED INDOLIZINO[1,2-b]QUINOLINONES

Publications (1)

Publication Number Publication Date
JPH07506099A true JPH07506099A (ja) 1995-07-06

Family

ID=25355849

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5518629A Pending JPH07506099A (ja) 1992-04-17 1993-04-15 置換インドリジノ[1,2−b]キノリノン

Country Status (8)

Country Link
EP (1) EP0637960A4 (enrdf_load_stackoverflow)
JP (1) JPH07506099A (enrdf_load_stackoverflow)
KR (1) KR950701219A (enrdf_load_stackoverflow)
CN (1) CN1083064A (enrdf_load_stackoverflow)
AU (1) AU4288893A (enrdf_load_stackoverflow)
CA (1) CA2118324A1 (enrdf_load_stackoverflow)
TW (1) TW264471B (enrdf_load_stackoverflow)
ZA (1) ZA932721B (enrdf_load_stackoverflow)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102093358B (zh) * 2011-02-21 2012-09-05 中山大学 溴代中氮茚并喹啉二酮类衍生物及其在制备抗菌药物中的应用
CN104398514B (zh) * 2014-10-28 2017-04-19 中山大学 氯喹在制备抗疱疹病毒药物中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5422344A (en) * 1990-05-08 1995-06-06 The United States Of America As Represented By The Secretary Of The Department Of Health & Human Services Method of treating retroviral infections in mammals
US5155225A (en) * 1990-09-28 1992-10-13 Smithkline Beecham Corporation Method for making certain pyrano[3',4':6,7]indolizino-[1,2-B]quinolinones
WO1992007856A1 (en) * 1990-10-31 1992-05-14 Smithkline Beecham Corporation SUBSTITUTED INDOLIZINO[1,2-b]QUINOLINONES

Also Published As

Publication number Publication date
EP0637960A4 (en) 1995-06-07
AU4288893A (en) 1993-11-18
EP0637960A1 (en) 1995-02-15
ZA932721B (en) 1993-11-29
KR950701219A (ko) 1995-03-23
TW264471B (enrdf_load_stackoverflow) 1995-12-01
CN1083064A (zh) 1994-03-02
CA2118324A1 (en) 1993-10-28

Similar Documents

Publication Publication Date Title
FI76087B (fi) Foerfarande foer framstaellning av terapeutiskt aktiva 9-(2-hydroxietoximetyl)guaninderivat.
SK133096A3 (en) Rapamycin hydroxyesters, process for their preparation and pharmaceutical compositions containing them
CA3113463A1 (en) Nitroxoline prodrug and use thereof
EP0778022A1 (en) Treatment of chlamydia infectious diseases by rifamycin derivative
JPH07504674A (ja) 抗ウイルス活性を有する更なるインドール誘導体
JP2022526604A (ja) タンパク質アルギニンメチルトランスフェラーゼ5の選択的阻害剤
IE913790A1 (en) SUBSTITUTED INDOLIZINO [1,2-b]QUINOLINONES
GB2158440A (en) 4,5,6,7-Tetrahydroimidazo[4,5-c]pyridine derivatives
WO2011017998A1 (zh) 藤黄酸环合类似物及其制备方法和应用
JP5261374B2 (ja) 抗ウイルス性ピリミジンヌクレオシド誘導体
US5883255A (en) Substituted indolizino 1,2-b!quinolinones
WO1993016698A1 (en) SUBSTITUTED FURO[3',4':6,7]INDOLIZINO[1,2-b]QUINOLINONES
JPH0577676B2 (enrdf_load_stackoverflow)
CN113698415A (zh) 一种新型的冬凌草甲素类似物及衍生物、其制备方法及医药用途
JPH07506099A (ja) 置換インドリジノ[1,2−b]キノリノン
CN101220037B (zh) 10-位取代高喜树碱类化合物及其用途
JPH08509740A (ja) カンプトテシンの水溶性誘導体
DE69819340T2 (de) Optisch reine camptothecinanaloge, optisch reines synthese-zwischenprodukt und verfahren zu ihrer herstellung
CN110903289B (zh) 嘌呤-氨甲基-吡啶酮衍生物及其制备方法和用途
WO1993020818A1 (en) SUBSTITUTED INDOLIZINO[1,2-b]QUINOLINONES
US4874779A (en) Mitomycin phosphate derivatives
CN115073481B (zh) 一种呋喃白坚木碱二聚体或其药学上可接受的盐及其制备方法和应用、药物组合物
GB1603127A (en) Rifamycin compounds
JPH04264092A (ja) シクロトリホスファゼンのn,oスピロ環状誘導体とその製法および用途
JPH0616560A (ja) 7−オキソ−7H−ピリド[1,2,3−de[1,4ベンゾキサジン−6−カルボン酸類およびエステル類の薬品としての使用