JPH07488A - Heat shrinkable extraction agent for galenical drug and method therefor - Google Patents

Abstract

PURPOSE:To reduce the bulk of a residue by extracting effective components of a galenical drug efficiently to facilitate extraction operation. CONSTITUTION:A galenical drug is wrapped with a heat shrinkable synthetic fiber net and a heat shrinkable synthetic film having numerous fine pores and dipped into a solvent to extract. This method eliminates the need for the operation of filtering a residue, thereby enabling easy removal of the residue with the bulkiness thereof reduced.

Description

Detailed Description of the Invention

[0001]

The present invention relates to a heat-shrinkable material having a net and fine pores of heat-shrinkable synthetic fibers which are spread while being extracted with a solvent when the crude drug is extracted with a solvent, and then packaged after extraction with the solvent. The present invention relates to accelerated extraction of active ingredients.

[0002]

2. Description of the Related Art When a crude drug is extracted with a solvent, the crude drug solution is obtained by immersing the crude drug in a solvent, heating, refluxing, vibrating, etc., and then simply removing the residue after extraction and filtering to remove the active ingredient. In such an extraction method, there are many inconveniences such as a long extraction time, a residue removal operation, a low extraction efficiency of the active ingredient, and a large residue. Therefore, the crude drug once extracted is washed, but there is a disadvantage that the extract becomes scarce. In addition, it is possible to perform pressure extraction with a compressor, but the operation becomes complicated.

[0003]

[Problems to be Solved by the Invention] When a crude drug is directly put into an extraction device and solvent extraction is performed, some small pieces remain when removing the residue, the active ingredient is lost together with the residue, and the active ingredient solution and the residue are filtered. Separately, the separation operation was complicated.
In addition, the extraction was insufficient even when the crude drug was put into the cloth bag and the amount of the active ingredient remaining in the residue was large. Therefore, there has been a strong demand for an extraction device and method that have good extraction efficiency, are easy to operate, and do not leave a bulky residue. TECHNICAL FIELD The present invention relates to an extraction device and method that have high extraction efficiency of crude drug, are easy to operate, and do not leave a large extraction residue.

[0004]

[Means for Solving the Problems] In order to efficiently and simply extract a crude drug, the crude drug is packaged in a heat-shrinkable film having a net and fine pores made of heat-shrinkable synthetic fibers, and after and during extraction in a solvent. To improve the extraction efficiency, reduce the amount of active ingredients in the residue, and reduce the volume of the residue. The type of synthetic fiber is not specified, but it is, for example, a braided product of polyamide, polyester, polyacryl, polyethylene, polypropylene alone or a blended fiber of two or more kinds. Any braiding method and fiber thickness may be used. You can fold it and wrap it, or put the crude drug in a net-processed bag. The heat shrinkage rate of the heat-shrinkable synthetic fiber net is preferably 100 ° C. and shrinks to 50% or less of the original length in both the longitudinal and lateral directions, but is not limited thereto. The types of heat-shrinkable synthetic resin films are polyethylene, polypropylene, poly-4-methylpentene-1, polyvinyl acetate, polyvinylidene chloride, polyputadiene, polyethylene phthalate, polybutyne terephthalate, polyamide homopolymers, copolymers and polymer alloys. Are suitable. However, the type of polymer is not limited as long as it is a film suitable for extracting a crude drug even if it is a polymer film other than these. The film has an arbitrary thickness of 0.01 mm to 1.0 mm. If it is less than 0.01 mm, the mechanical strength of the film is insufficient, and if it is more than 1.0 mm, it becomes difficult. However, the present invention is not limited by the film thickness. The inner diameter of the fine holes is preferably 0.01 mm to 2.0 mm, and the circular shape is most suitable, but other hole shapes may be used. If the inner diameter of the large number of micropores is 0.01 mm or less, the solvent and crude drug extract component solution passing through the synthetic resin film will be slow, and if the inner diameter is 2.0 mm or more, the herbal medicine will be leaked. However, the present invention is not limited by the size of the micropores and the number of micropores. The heat shrinkage rate of the synthetic resin film is preferably 50% or less of the film size before shrinkage at any temperature in both longitudinal and lateral directions. The squeezing force of the crude drug in the solvent is controlled by the type, size, shrinkage rate of the film and the packaging device of the crude drug. The heat-shrinkable synthetic resin film may be used in a furoshiki type, but if it is made into a bag shape, the one-layer object of the present invention can be more easily achieved. An inner sheet or an inner bag may be appropriately used inside the heat-shrinkable synthetic fiber net and the heat-shrinkable synthetic resin film. The inner sheet or inner bag acts as a heat-shrinkable net, reinforcing the porous film, and preventing the leakage of crude drug. The inner sheet or inner bag may be fiber cloth, paper or non-woven cloth. There are the following three mechanisms for extracting and squeezing crude drugs. The first is extraction after squeezing with a heat-shrinkable net or heat-shrinkable film. The second is extracted while narrowing down. Third, narrow down after extraction. It is most common to extract after the first restriction. When a crude drug is put into a heat-shrinkable low-density polyethylene net stretched at 100 ° C. and extracted in boiling water, the drug is heat-shrinked simultaneously with the extraction, and the crude drug is squeezed and extracted. Secondly, when a crude drug is put in a heat-shrinkable low-density polyethylene net stretched at 100 ° C and put in hot water at 90 ° C, the net contracts slowly and is extracted while squeezing. Third, put the herbal medicine in a heat-shrinkable polypropylene net stretched at 120 ° C and put it in a pressure vessel at 100 ° C.
When extraction is performed in water and then the temperature is raised to 120 ° C, the polypropylene net contracts and the crude drug is squeezed. The extract of crude drug and the method of extracting it due to this outbreak have the advantage that they can be used on a large scale for industrial use or on a small scale for household use.

[0005]

The herb medicine is packed with the heat-shrinkable synthetic fiber net and the heat-shrinkable synthetic resin film having a large number of fine pores according to the present invention and extracted in a solvent. Facilitate. As the shrinkage progresses, the net and film have narrower voids, preventing the leakage of herbal medicines.

[0006]

【Example】

1. After molding the string with polypropylene, it was stretched 5 times to obtain a heat-shrinkable string having a cross section of 0.4 mm in diameter. This string yielded a twill net with one side of 1,6 mm. 20 cm on one side from this net
I made a square bag. Ginseng 500 cut into bags
Fill g. Next, the ginseng packed in the bag was extracted for 3 hours at 100 ° C boiling water at a normal pressure in a 2 liter pressure vessel and then at 130 ° C for 15 hours.
Heated by pressure. The extract in the obtained extract was 24% of ginseng. No small pieces of ginseng leaked into the extract, and the residue was small and collected in a net. Similarly, when the same ginseng was extracted without using the net, the extracted content was 19% of ginseng. Further, it was complicated to remove the residue from the pressure vessel. 2. 500 g of ground ginseng is packed in a square bag having a side of 20 cm and made of a 0.05 mm thick biaxially shrinkable polyethylene film having 25 holes having a diameter of 0.2 mm in 1 cm ² . This was extracted in 2 l of boiling water for 3 hours. The extract was 21% of ginseng. There were no small pieces of ginseng in the extract, and the residue was small and collected in a bag.
Similarly, when the same extraction was performed using the same ginseng without using a bag, the extracted content was 17% of ginseng. The residue had to be filtered off.

[0007]

EFFECTS OF THE INVENTION When a herbal medicine is packaged and extracted in a solvent with a heat-shrinkable synthetic fiber net and a heat-shrinkable synthetic film having a large number of fine pores according to the present invention, the extraction amount of the active ingredient increases and the extraction operation This facilitates the treatment, reduces the amount of active ingredient attached to the residue, reduces the volume of the residue, and facilitates handling.

Claims (4)

[Claims] 1. A net-form crude drug extract made of heat-shrinkable synthetic fiber 2. A method for extracting a crude drug packaged with the net-form crude drug extract material according to claim 1. 3. A crude drug extract material comprising a heat-shrinkable film having fine pores. 4. A method for extracting a crude drug packaged with the heat-shrinkable film according to claim 3.