JPH07119217B2 - 新規ベンゾジアゼピン誘導体 - Google Patents

新規ベンゾジアゼピン誘導体

Info

Publication number
JPH07119217B2
JPH07119217B2 JP4-501765A JP50176592A JPH07119217B2 JP H07119217 B2 JPH07119217 B2 JP H07119217B2 JP 50176592 A JP50176592 A JP 50176592A JP H07119217 B2 JPH07119217 B2 JP H07119217B2
Authority
JP
Japan
Prior art keywords
dihydro
phenyl
benzodiazepin
compound
methylphenacyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP4-501765A
Other languages
English (en)
Japanese (ja)
Other versions
JPH07119217B1 (enExample
JPWO1992011246A1 (ja
Inventor
正人 佐藤
裕 近藤
芳典 岡本
明登 西田
一男 本田
仁之 斎藤
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamanouchi Pharmaceutical Co Ltd
Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Pharmaceutical Co Ltd filed Critical Yamanouchi Pharmaceutical Co Ltd
Publication of JPWO1992011246A1 publication Critical patent/JPWO1992011246A1/ja
Publication of JPH07119217B2 publication Critical patent/JPH07119217B2/ja
Publication of JPH07119217B1 publication Critical patent/JPH07119217B1/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/08—Containers or packages with special means for dispensing contents for dispensing thin flat articles in succession
    • B65D83/0847—Containers or packages with special means for dispensing contents for dispensing thin flat articles in succession through an aperture at the junction of two walls
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65H—HANDLING THIN OR FILAMENTARY MATERIAL, e.g. SHEETS, WEBS, CABLES
    • B65H35/00—Delivering articles from cutting or line-perforating machines; Article or web delivery apparatus incorporating cutting or line-perforating devices, e.g. adhesive tape dispensers
    • B65H35/10—Delivering articles from cutting or line-perforating machines; Article or web delivery apparatus incorporating cutting or line-perforating devices, e.g. adhesive tape dispensers from or with devices for breaking partially-cut or perforated webs, e.g. bursters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65H—HANDLING THIN OR FILAMENTARY MATERIAL, e.g. SHEETS, WEBS, CABLES
    • B65H2701/00—Handled material; Storage means
    • B65H2701/10—Handled articles or webs
    • B65H2701/11—Dimensional aspect of article or web
    • B65H2701/112—Section geometry
    • B65H2701/1123—Folded article or web
    • B65H2701/11231—Fan-folded material or zig-zag or leporello

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP4-501765A 1990-12-25 1991-12-17 新規ベンゾジアゼピン誘導体 Expired - Lifetime JPH07119217B2 (ja)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP2-418263 1990-12-25
JP41826390 1990-12-25
JP3-111216 1991-02-20
JP11121691 1991-02-20
JP3-282056 1991-10-02
JP28205691 1991-10-02

Publications (3)

Publication Number Publication Date
JPWO1992011246A1 JPWO1992011246A1 (ja) 1993-01-14
JPH07119217B2 true JPH07119217B2 (ja) 1995-12-20
JPH07119217B1 JPH07119217B1 (enExample) 1995-12-20

Family

ID=27311908

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4-501765A Expired - Lifetime JPH07119217B2 (ja) 1990-12-25 1991-12-17 新規ベンゾジアゼピン誘導体

Country Status (10)

Country Link
US (1) US5541182A (enExample)
EP (1) EP0591529A1 (enExample)
JP (1) JPH07119217B2 (enExample)
CN (1) CN1063103A (enExample)
AU (1) AU656754B2 (enExample)
CA (1) CA2099672A1 (enExample)
FI (1) FI932928L (enExample)
HU (1) HUT67299A (enExample)
TW (1) TW205544B (enExample)
WO (1) WO1992011246A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2099672A1 (en) * 1990-12-25 1992-06-26 Masato Satoh Benzodiazepine derivatives
AU2759692A (en) * 1991-10-24 1993-05-21 Glaxo Group Limited Benzodiazepine derivatives as antagonists of gastrin and/or cholecystokinin
JP2726158B2 (ja) 1992-06-24 1998-03-11 山之内製薬株式会社 新規ベンゾジアゼピン誘導体
WO1994000438A1 (fr) * 1992-06-24 1994-01-06 Yamanouchi Pharmaceutical Co., Ltd. Nouveau derive de benzodiazepine
EP0708094A4 (en) * 1993-07-06 1996-08-28 Yamanouchi Pharma Co Ltd NEW CRYSTAL OF A BENZODIAZEPINE DERIVATE
GB2282595A (en) * 1993-08-25 1995-04-12 Yamanouchi Pharma Co Ltd Benzodiazepine derivatives
US6635632B1 (en) 1996-12-23 2003-10-21 Athena Neurosciences, Inc. Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
US6683075B1 (en) 1996-12-23 2004-01-27 Athena Neurosciences, Inc. Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use
US6958330B1 (en) 1998-06-22 2005-10-25 Elan Pharmaceuticals, Inc. Polycyclic α-amino-ε-caprolactams and related compounds
US6569851B1 (en) * 1998-06-22 2003-05-27 Elan Pharmaceutials, Inc. Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
US20050192265A1 (en) * 2003-03-20 2005-09-01 Thompson Richard C. Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
AU2014352875B2 (en) 2013-11-22 2019-10-24 CL BioSciences LLC Gastrin antagonists (eg YF476, netazepide) for treatment and prevention of osteoporosis
US10881667B2 (en) 2018-10-30 2021-01-05 City University Of Hong Kong Method and composition for treating epilepsy
US11285161B2 (en) 2019-04-26 2022-03-29 City University Of Hong Kong Method and composition for treating mental disorder and pain associated with nerve damage

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4032004A (en) * 1975-07-09 1977-06-28 Francis William Coates Ticket dispensing arrangement
JPS54157585A (en) * 1978-05-30 1979-12-12 Yasumitsu Tamura Manufacture of 1*44benzodiazepin
US5004741A (en) * 1984-06-26 1991-04-02 Merck & Co., Inc. Methods of antagonizing CCK or gastrin with benzodiazepine analogs
US4820834A (en) * 1984-06-26 1989-04-11 Merck & Co., Inc. Benzodiazepine analogs
CA1332410C (en) * 1984-06-26 1994-10-11 Roger M. Freidinger Benzodiazepine analogs
JPS6178773A (ja) * 1984-09-21 1986-04-22 メドサン　インダストリ−　バイオキミケ　リウニテ　ソチエタ　ペル　アツイオニ Ｃ―３置換１，４―ベンゾジアゼピンおよび医薬組成物
IL96613A0 (en) * 1989-12-18 1991-09-16 Merck & Co Inc Pharmaceutical compositions containing benzodiazepine analogs
GB9015879D0 (en) * 1990-07-19 1990-09-05 Fujisawa Pharmaceutical Co Benzodiazepine derivatives
CA2099672A1 (en) * 1990-12-25 1992-06-26 Masato Satoh Benzodiazepine derivatives

Also Published As

Publication number Publication date
FI932928A7 (fi) 1993-06-24
TW205544B (enExample) 1993-05-11
EP0591529A4 (en) 1993-09-20
WO1992011246A1 (en) 1992-07-09
JPH07119217B1 (enExample) 1995-12-20
FI932928A0 (fi) 1993-06-24
FI932928L (fi) 1993-06-24
AU9050491A (en) 1992-07-22
US5541182A (en) 1996-07-30
EP0591529A1 (en) 1994-04-13
HUT67299A (en) 1995-03-28
CN1063103A (zh) 1992-07-29
CA2099672A1 (en) 1992-06-26
AU656754B2 (en) 1995-02-16
HU9301869D0 (en) 1993-09-28

Similar Documents

Publication Publication Date Title
US5681833A (en) Benzodiazepine derivatives
US5597915A (en) Benzodiazepine derivatives, compositions containing them and their use in therapy
EP0538945A1 (en) Benzodiazepine derivatives, and their use as antagonists of gastrin and/or cholecystokinin
EP0672037B1 (en) 1,4-benzodiazepine derivatives and their use as cck-modulators
US5451582A (en) Benzodiazepine derivatives, compositions containing them and their use in therapy
JPH07119217B2 (ja) 新規ベンゾジアゼピン誘導体
US5521175A (en) Benzodiazepine derivatives
JPWO1992011246A1 (ja) 新規ベンゾジアゼピン誘導体
AU2788792A (en) Benzodiazepine derivatives and their use as antagonists of cholecystokinin and/or gastrin receptors
EP0715624B1 (en) Process for the preparation of benzodiazepine compounds useful as antagonists of cck or of gastrine
CA2066083C (en) Benzodiazepine analogs as cholecystokinin antagonists
HUT68208A (en) Novel benzodiazepine derivatives and pharmaceutical preparations containing them
AU776283B2 (en) Calcium salts of 1,5-benzodiazepine derivatives, process for producing the salts and drugs containing the same
US5641775A (en) 3-phenylureido-1,5-benzodiazepine-diones useful as gastrin or antagonists
WO1995006041A1 (en) 3-phenylureido-1,4-benzodiazepines useful as selective cck-b antagonists
JP2726158B2 (ja) 新規ベンゾジアゼピン誘導体
JPH04297479A (ja) 新規チェノジアゼピン誘導体
JPWO1994000438A1 (ja) 新規ベンゾジアゼピン誘導体