JPH0662896A - スペルミジン／スペルミンｎ１−アセチルトランスフェラーゼの、予後インジケータ及び／又は腫瘍応答マーカーとしての使用方法 - Google Patents

スペルミジン／スペルミンｎ１−アセチルトランスフェラーゼの、予後インジケータ及び／又は腫瘍応答マーカーとしての使用方法

Info

Publication number
JPH0662896A
JPH0662896A JP5124961A JP12496193A JPH0662896A JP H0662896 A JPH0662896 A JP H0662896A JP 5124961 A JP5124961 A JP 5124961A JP 12496193 A JP12496193 A JP 12496193A JP H0662896 A JPH0662896 A JP H0662896A
Authority
JP
Japan
Prior art keywords
spermine
spermidine
acetyltransferase
assay
induction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP5124961A
Other languages
English (en)
Japanese (ja)
Inventor
Carl W Porter
ダブリュー、ポーター カール
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Health Research Inc
Original Assignee
Health Research Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Health Research Inc filed Critical Health Research Inc
Publication of JPH0662896A publication Critical patent/JPH0662896A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP5124961A 1992-04-28 1993-04-27 スペルミジン／スペルミンｎ１−アセチルトランスフェラーゼの、予後インジケータ及び／又は腫瘍応答マーカーとしての使用方法 Pending JPH0662896A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US87509192A 1992-04-28 1992-04-28
US07/875091 1992-04-28

Publications (1)

Publication Number Publication Date
JPH0662896A true JPH0662896A (ja) 1994-03-08

Family

ID=25365191

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5124961A Pending JPH0662896A (ja) 1992-04-28 1993-04-27 スペルミジン／スペルミンｎ１−アセチルトランスフェラーゼの、予後インジケータ及び／又は腫瘍応答マーカーとしての使用方法

Country Status (4)

Country Link
US (1) US5498522A (cg-RX-API-DMAC7.html)
EP (1) EP0568338A2 (cg-RX-API-DMAC7.html)
JP (1) JPH0662896A (cg-RX-API-DMAC7.html)
CA (1) CA2094341A1 (cg-RX-API-DMAC7.html)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000074917A (ja) * 1998-08-27 2000-03-14 Yamasa Shoyu Co Ltd ジアセチルポリアミンの測定法及びキット
JP2007176948A (ja) * 1999-02-05 2007-07-12 Mediquest Therapeutics Inc アンチザイムモジュレーターおよびその使用

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5674908A (en) 1993-12-20 1997-10-07 Life Technologies, Inc. Highly packed polycationic ammonium, sulfonium and phosphonium lipids
US5650096A (en) * 1994-12-09 1997-07-22 Genzyme Corporation Cationic amphiphiles for intracellular delivery of therapeutic molecules
WO1996033703A2 (en) * 1995-04-25 1996-10-31 Oridigm Corporation S-adenosyl methionine regulation of metabolic pathways and its use in diagnosis and therapy
US6274630B1 (en) * 1996-09-13 2001-08-14 University Of Florida Research Foundation, Inc. Method of inhibiting biosynthesis of EIf5A
US7087648B1 (en) 1997-10-27 2006-08-08 The Regents Of The University Of California Methods for modulating macrophage proliferation using polyamine analogs
AU2003231670B2 (en) * 1997-10-27 2006-06-08 Slil Biomedical Corporation Methods for modulating macrophage proliferation using polyamine analogs
US8198334B2 (en) * 1997-10-27 2012-06-12 Pathologica Llc Methods for modulating macrophage proliferation in ocular disease using polyamine analogs
ATE383331T1 (de) 1998-11-12 2008-01-15 Invitrogen Corp Transportreagentien
US7312244B2 (en) * 1999-04-30 2007-12-25 Cellgate, Inc. Polyamine analog-amino acid conjugates useful as anticancer agents
NZ515140A (en) 1999-04-30 2003-07-25 Slil Biomedical Corp Conformationally restricted polyamine analogs as disease therapies for cancer, epilepsy, alzheimers, infections, grafts and others
MXPA01011008A (es) * 1999-04-30 2003-06-30 Slil Biomedical Corp Conjugados analogos de poliamina y conjugados de quinona novedosos como terapia para canceres y enfermedades de la prostata.
US6649587B1 (en) 1999-04-30 2003-11-18 Slil Biomedical Corporation Polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases
US6482943B1 (en) 1999-04-30 2002-11-19 Slil Biomedical Corporation Quinones as disease therapies
MXPA02006843A (es) * 2000-01-12 2004-04-05 Ventana Med Syst Inc Metodo para cuantificar una proteina por analisis de imagenes.
US7273888B2 (en) * 2001-11-16 2007-09-25 Als Therapy Development Foundation, Inc. Use of difluoromethylornithine (DFMO) for the treatment of amyotrophic lateral sclerosis
WO2003050072A1 (en) * 2001-12-07 2003-06-19 Slil Biomedical Corporation Cycloalkyl substituted polyamines for cancer therapy and methods of synthesis therefor
JP2004189714A (ja) * 2002-12-09 2004-07-08 Rasanen Tiina-Liisa すい臓炎の治療と予防ならびに肝臓再生機能の誘導のための薬剤
CN102344950B (zh) * 2011-05-31 2015-08-26 上海拜瑞曼克生物科技有限公司 一种用于检测ssat底物的乙酰化代谢物的方法
US9585380B2 (en) 2011-09-02 2017-03-07 Temple University—Of the Commonwealth System of Higher Education SSAT mRNA translation repression and activation
CA2900108A1 (en) * 2013-01-30 2014-08-07 Biomark Technologies Inc. Spermidine/spermine n1-acetyltransferase antibodies as anti-cancer drug compounds
WO2016011203A1 (en) 2014-07-15 2016-01-21 Life Technologies Corporation Compositions with lipid aggregates and methods for efficient delivery of molecules to cells

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000074917A (ja) * 1998-08-27 2000-03-14 Yamasa Shoyu Co Ltd ジアセチルポリアミンの測定法及びキット
JP2007176948A (ja) * 1999-02-05 2007-07-12 Mediquest Therapeutics Inc アンチザイムモジュレーターおよびその使用

Also Published As

Publication number Publication date
US5498522A (en) 1996-03-12
EP0568338A2 (en) 1993-11-03
CA2094341A1 (en) 1993-10-29
EP0568338A3 (cg-RX-API-DMAC7.html) 1994-03-30

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