JPH0655082B2 - Method for preventing or recoloring body color of red seafood by .GAMMA.-pyrone derivative - Google Patents

Method for preventing or recoloring body color of red seafood by .GAMMA.-pyrone derivative

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Publication number
JPH0655082B2
JPH0655082B2 JP3833185A JP3833185A JPH0655082B2 JP H0655082 B2 JPH0655082 B2 JP H0655082B2 JP 3833185 A JP3833185 A JP 3833185A JP 3833185 A JP3833185 A JP 3833185A JP H0655082 B2 JPH0655082 B2 JP H0655082B2
Authority
JP
Japan
Prior art keywords
red
seafood
body color
pyrone derivative
preventing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP3833185A
Other languages
Japanese (ja)
Other versions
JPS61197506A (en
Inventor
日出彦 高橋
Original Assignee
株式会社薬理学中央研究所
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 株式会社薬理学中央研究所 filed Critical 株式会社薬理学中央研究所
Priority to JP3833185A priority Critical patent/JPH0655082B2/en
Publication of JPS61197506A publication Critical patent/JPS61197506A/en
Publication of JPH0655082B2 publication Critical patent/JPH0655082B2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations

Description

【発明の詳細な説明】 本発明はγ−ピロン誘導体配合飼料投与による養殖赤色
魚介類の体色の黒変防止又は復色方法に関する。さらに
詳細には紫外線の影響による赤色魚介類の体色の黒変を
防止するため、麹、酸、コメン酸、ピロコメン酸及びそ
れらのエスエル類、マルトール、エチルマルトール、ヒ
ドロキシマルトール（３−ヒドロキシ−２−ヒドロキシ
−メチル−４(H)−ピラン−４−オン）などのピロン誘
導体を飼育海水、淡水又は飼料に配合して投与すること
により養殖中の赤色魚介類の体表面色を、紫外線照射に
よる黒変から防止し、もしくは元の色へ復色する方法に
関する。The present invention relates to a method for preventing or discoloring body color of cultured red seafood by administering a feed containing a γ-pyrone derivative. More specifically, in order to prevent the blackening of the body color of red seafood due to the influence of ultraviolet rays, koji, acid, comenic acid, pyrocomenic acid and their esters, maltol, ethylmaltol, hydroxymaltol (3-hydroxy-2) -Hydroxy-methyl-4 (H) -pyran-4-one) and other pyrone derivatives are added to the breeding seawater, fresh water or feed to administer the body surface color of the red seafood during cultivation. The present invention relates to a method for preventing blackening or restoring the original color.

紫外線による赤色魚介類の体色の黒変としては、甲殻類
特にえび類、魚類特に鯛類の体表面黒変が本発明の対象
となる。The subject of the present invention is the blackening of the body color of red seafood due to ultraviolet rays, which is the blackening of the body surface of crustaceans, especially shrimp, and fish, especially sea bream.

植物界、動物界の生体色素、就中体色を支配する色素と
してのカロチノイドとメラミンの意義については近年益
々知見が増大してきている。The significance of carotenoids and melamine as vital pigments of the plant kingdom and animal kingdom, and as pigments that control body color, has been increasing in recent years.

ヒトに於ては皮膚、毛髪の色は共にメラニン色素に専ら
支配され、人種問題の生物学的要因の一つとして重視さ
れるばかりでなく、肝斑、ソバカス、日やけなどの生起
との関連も注目されている。In humans, both skin and hair colors are exclusively governed by melanin pigments and are not only emphasized as one of the biological factors of racial problems, but also with the occurrence of melasma, freckles, sunburn, etc. Relations are also drawing attention.

甲殻類、魚類、鳥類、その他の動物に於てはカロチノイ
ドが体色の色素として重要な意義を有するものが多く、
これとメラニン色素とは微妙にかかわり合っていること
も、次第に明らかにされようとしている。このことは有
色食品、例えばえび、鯛などの養殖、保存などの上で体
色の変化として重要な経済的問題を提起している。In crustaceans, fish, birds, and other animals, carotenoids are often important as body color pigments.
The subtle relationship between this and melanin pigments is gradually being clarified. This poses an important economic problem as a change in body color when culturing and preserving colored foods such as shrimp and sea bream.

本発明は長い間、メラニン色素とカロチノイド類の研究
にかかわってきたが、上述の諸問題にも解決策をもとめ
て長い試行錯誤の後、本発明に完成したのである。The present invention has long been involved in the study of melanin pigments and carotenoids, but the present invention was completed after a long trial and error in finding solutions to the above problems.

参考例 ０．０５％のＬ−ドーパ水溶液（pH７．０りん酸バッフ
ァー）に空気を劇しく吹きこみ、液の黒変を４７０ｎｍ
の波長の吸収によって測定する。この反応はドーパ−メ
ラニンの生成を示すもので、室温に於ては約３日間で反
応が終了する。Reference example Air was blown into 0.05% L-DOPA aqueous solution (pH 7.0 phosphate buffer) dramatically, and the blackening of the liquid was changed to 470 nm.
It is measured by the absorption of the wavelength of. This reaction shows the production of dopa-melanin, and the reaction is completed in about 3 days at room temperature.

され、この反応を紫外線照射下で行うと、著しく促進さ
れる。光源にＵＭ−４５２（ウシオ電機）の高圧水銀燈
（３６５〜５７９．１ｎｍ間に強い線スペクトルを有す
る）を使用し、光源と検体間の距離９５mm、液温２０〜
２５℃の条件下で上述の反応を行うとほぼ３時間で終了
する。When this reaction is carried out under UV irradiation, it is significantly accelerated. A high-pressure mercury lamp (having a strong line spectrum between 365 and 579.1 nm) of UM-452 (USHIO INC.) Is used as a light source, the distance between the light source and the specimen is 95 mm, and the liquid temperature is 20-
When the above reaction is performed under the condition of 25 ° C., the reaction is completed in about 3 hours.

γ−ピロン誘導体を０．０１％の濃度で反応液相に加え
ると、この紫外線照射の影響は著しく抑制される。When the γ-pyrone derivative is added to the reaction liquid phase at a concentration of 0.01%, the effect of this ultraviolet irradiation is significantly suppressed.

実施例１ 黒色金魚に対するγ−ピロン誘導体の作用 ０．２５〜１％ピロン誘導体で黒色金魚を飼育する時、
黒色がうすれ、黄色になる。麹酸の作用を標準として、
他のγ−ピロン誘導体の作用を比較した。 Example 1 Effect of γ-pyrone derivative on black goldfish When a black goldfish is reared with 0.25 to 1% pyrone derivative,
Black color fades to yellow. Based on the action of koji acid,
The effects of other γ-pyrone derivatives were compared.

γ−ピロン誘導体によって、黄色になった黒色金魚を純
水にかえし、紫外線を照射すると速やかに黒色が快復し
たが、その際γ−ピロン誘導体を０．１％加えると、金
魚の黒化は著しく抑制された。この抑制作用はマルトー
ルが最も顕著であった。 The black goldfish that turned yellow by the γ-pyrone derivative was replaced with pure water, and the black color was promptly restored by irradiation with ultraviolet rays. At that time, if 0.1% of the γ-pyrone derivative was added, the blackening of the goldfish was remarkable. Suppressed This inhibitory effect was most prominent in maltol.

赤色の鯛の紫外線による体色の黒化は商品価値を著しく
低下させるものであるが、紫外線の照射のため水槽中の
鯛の体色（カロチノイド）の黒化も金魚と同様γ−ピロ
ンによって防止された。 The blackening of red sea bream due to UV light significantly reduces the commercial value, but the blackening of sea bream body color (carotenoid) in the aquarium due to UV irradiation is also prevented by γ-pyrone, similar to goldfish. Was done.

実施例２ 車えびの体色に及ぼすγ−ピロンの影響 車えびを浅い人工海水中で飼育し、紫外線を照射すると
体色が著しく黒変する。これはメラニン形成が高まるた
めと思われる。この時人工海水に０．１％のγ−ピロン
誘導体を加えると著しく黒化がおさえられた。Example 2 Effect of γ-pyrone on body color of prawns When prawns are reared in shallow artificial seawater and irradiated with ultraviolet rays, the body color of the prawns remarkably changes to black. This is probably due to increased melanogenesis. At this time, blackening was remarkably suppressed when 0.1% γ-pyrone derivative was added to the artificial seawater.

フロントページの続き (56)参考文献 特開 昭53−18739（ＪＰ，Ａ) 特開 昭53−3538（ＪＰ，Ａ) 特開 昭59−122485（ＪＰ，Ａ) 特開 昭57−134409（ＪＰ，Ａ) 特開 昭56−7710（ＪＰ，Ａ) 特開 昭59−33207（ＪＰ，Ａ) 特開 昭56−79616（ＪＰ，Ａ) 特開 昭57−72978（ＪＰ，Ａ) 特開 昭55−157580（ＪＰ，Ａ) 特開 昭56−7776（ＪＰ，Ａ) 特開 昭57−136508（ＪＰ，Ａ) 特開 昭57−35506（ＪＰ，Ａ) 特開 昭57−14517（ＪＰ，Ａ) 特開 昭55−143908（ＪＰ，Ａ)Continuation of front page (56) Reference JP-A-53-18739 (JP, A) JP-A-53-3538 (JP, A) JP-A-59-122485 (JP, A) JP-A-57-134409 (JP , A) JP 56-7710 (JP, A) JP 59-33207 (JP, A) JP 56-79616 (JP, A) JP 57-72978 (JP, A) JP 55-157580 (JP, A) JP-A-56-7776 (JP, A) JP-A-57-136508 (JP, A) JP-A-57-35506 (JP, A) JP-A-57-14517 (JP, A) A) JP-A-55-143908 (JP, A)

Claims (3)

【特許請求の範囲】[Claims] 【請求項１】γ−ピロン誘導体を経口投与することを特
徴とする、赤色魚介類の紫外線による体色黒変を防止又
は復色させる方法。1. A method for preventing or recoloring body color blackening of red seafood caused by ultraviolet rays, which comprises orally administering a γ-pyrone derivative. 【請求項２】γ−ピロン誘導体を赤色魚介類の飼育海水
又は淡水中に投与するか、或いは飼育に含有させて経口
投与する特許請求の範囲第１項に記載の方法。2. The method according to claim 1, wherein the γ-pyrone derivative is administered to seawater or freshwater for breeding red seafood or orally contained in the breeding for oral administration. 【請求項３】γ−ピロン誘導体がマルトール、ピロコメ
ン酸、コメン酸及びコウジ酸から選ばれる、特許請求の
範囲第１項の記載の方法。3. The method according to claim 1, wherein the γ-pyrone derivative is selected from maltol, pyrocomenic acid, comenic acid and kojic acid.
JP3833185A 1985-02-27 1985-02-27 Method for preventing or recoloring body color of red seafood by .GAMMA.-pyrone derivative Expired - Lifetime JPH0655082B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP3833185A JPH0655082B2 (en) 1985-02-27 1985-02-27 Method for preventing or recoloring body color of red seafood by .GAMMA.-pyrone derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3833185A JPH0655082B2 (en) 1985-02-27 1985-02-27 Method for preventing or recoloring body color of red seafood by .GAMMA.-pyrone derivative

Publications (2)

Publication Number Publication Date
JPS61197506A JPS61197506A (en) 1986-09-01
JPH0655082B2 true JPH0655082B2 (en) 1994-07-27

Family

ID=12522293

Family Applications (1)

Application Number Title Priority Date Filing Date
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Country Status (1)

Country Link
JP (1) JPH0655082B2 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62198372A (en) * 1986-02-24 1987-09-02 Nippon Seifun Kk Agent for keeping freshness of perishable food and method for keeping same
JPS6434241A (en) * 1987-07-30 1989-02-03 Seiwa Kasei Kk Freshness preservation of vegetable, fruit and cut flower
EP0313305A3 (en) * 1987-10-22 1990-02-07 The Procter & Gamble Company Photoprotection compositions comprising chelating agents
JPH0330637A (en) * 1989-06-27 1991-02-08 Taiyo Fishery Co Ltd Method for improving body color of cultured fish
JPH03127712A (en) * 1989-10-09 1991-05-30 Sansho Seiyaku Co Ltd Agent for external application
FR2787711B1 (en) * 1998-12-29 2002-12-06 C3D Sarl COSMETIC COMPOSITION WITH DEPIGMENTING ACTIVITY AND ITS USE
IT1316059B1 (en) * 1999-09-09 2003-03-28 Carlo Ghisalberti SKIN DEPIGMENTANTS.
CN103314896B (en) * 2013-06-17 2015-10-28 苏州市阳澄湖现代农业产业园特种水产养殖有限公司 A kind of swamp eel, loach lotus rhizome pond cover breeding method
CN103355233B (en) * 2013-07-10 2015-02-25 浙江大学 Black fading method of juvenile blood parrot fishes
WO2017127025A1 (en) * 2016-01-19 2017-07-27 Namz Pte. Ltd. A cosmetic composition and the use thereof for regulating skin quality
CN106069926B (en) * 2016-06-23 2018-11-02 钦州市桂珍深海养殖有限公司 The cultural method of golden pomfret
CN110292010A (en) * 2019-07-30 2019-10-01 安徽玺莲生态农业有限公司 A kind of lobster cultivation method based on rice field and lotus rhizome

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS533538A (en) * 1976-06-28 1978-01-13 Sansho Seiyaku Kk Skin bleach cosmetics
JPS5318739A (en) * 1976-08-03 1978-02-21 Sansho Seiyaku Kk Decolorant for external application
JPS55143908A (en) * 1979-04-25 1980-11-10 Sansho Seiyaku Kk Fair cosmetic
JPS5834477B2 (en) * 1979-05-25 1983-07-27 三省製薬株式会社 Fatty acid ester of quercetin
JPS567710A (en) * 1979-06-28 1981-01-27 Sansho Seiyaku Kk Whitening cosmetic
JPS5822151B2 (en) * 1979-10-22 1983-05-06 三省製薬株式会社 Kojic acid diester
JPS609722B2 (en) * 1979-12-05 1985-03-12 三省製薬株式会社 fair skin cosmetics
JPS5714517A (en) * 1980-06-27 1982-01-25 Sansho Seiyaku Kk Whitening cosmetic
JPS5735506A (en) * 1980-08-11 1982-02-26 Sansho Seiyaku Kk Bleaching cosmetic
JPS5935884B2 (en) * 1980-10-27 1984-08-31 株式会社 薬理学中央研究所 Melanin production inhibitor containing pyranone
JPS57134409A (en) * 1981-02-13 1982-08-19 Sansho Seiyaku Kk Whitening cosmetic
JPS57136508A (en) * 1981-02-17 1982-08-23 Sansho Seiyaku Kk Whitening cosmetic
JPS6010005B2 (en) * 1982-08-20 1985-03-14 三省製薬株式会社 fair skin cosmetics
JPS59122485A (en) * 1982-12-29 1984-07-14 Sansho Seiyaku Kk Kojic acid derivative and lightening cosmetic containing the same as active ingredient

Also Published As

Publication number Publication date
JPS61197506A (en) 1986-09-01

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