JPH06500555A - - Google Patents

Info

Publication number
JPH06500555A
JPH06500555A JP51533691A JP51533691A JPH06500555A JP H06500555 A JPH06500555 A JP H06500555A JP 51533691 A JP51533691 A JP 51533691A JP 51533691 A JP51533691 A JP 51533691A JP H06500555 A JPH06500555 A JP H06500555A
Authority
JP
Grant status
Application
Patent type
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP51533691A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70546Integrin superfamily
    • C07K14/70553Integrin beta2-subunit-containing molecules, e.g. CD11, CD18
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00Medicinal preparations containing peptides
JP51533691A 1990-08-27 1991-08-23 Pending JPH06500555A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US57362490 true 1990-08-27 1990-08-27

Publications (1)

Publication Number Publication Date
JPH06500555A true true JPH06500555A (en) 1994-01-20

Family

ID=24292747

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51533691A Pending JPH06500555A (en) 1990-08-27 1991-08-23

Country Status (5)

Country Link
US (1) US5340800A (en)
EP (1) EP0546077A1 (en)
JP (1) JPH06500555A (en)
CA (1) CA2090427A1 (en)
WO (1) WO1992003473A1 (en)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6143298A (en) * 1988-09-01 2000-11-07 Bayer Corporation Soluble truncated forms of ICAM-1
US6051231A (en) * 1988-09-01 2000-04-18 Bayer Corporation Antiviral methods and prepations
US6514936B1 (en) 1988-09-01 2003-02-04 Bayer Corporation Antiviral methods using human rhinovirus receptor (ICAM-1)
DE68929096D1 (en) 1988-09-01 1999-12-16 Bayer Ag Human rhinovirus receptor protein that inhibits the viral infection susceptibility
US6130202A (en) * 1990-07-20 2000-10-10 Bayer Corporation Antiviral methods
US6107461A (en) * 1990-07-20 2000-08-22 Bayer Corporation Multimeric forms of human rhinovirus receptor and fragments thereof, and method of use
DE69131564D1 (en) * 1990-07-20 1999-10-07 Bayer Ag Multimeric forms of the human rhinovirus receptor protein
GB9115364D0 (en) * 1991-07-16 1991-08-28 Wellcome Found Antibody
US5854070A (en) * 1992-07-16 1998-12-29 Icos Corporation Murine and humanizer 23F2G antibodies and cell lines expressing said antibodies
EP1069182A1 (en) 1992-07-16 2001-01-17 Icos Corporation Alleviation of symptoms associated with inflammatory disease states, using antibodies to CD18
JPH09512021A (en) * 1994-04-19 1997-12-02 ザ ユニバーシティ オブ カンサス Using Icam-1 / lfa-1 short peptides and peptide
DK0852491T3 (en) * 1995-09-29 2004-12-20 Biomarin Pharm Inc Use of heparinases to reduce inflammatory responses
US6075004A (en) 1996-04-26 2000-06-13 The University Of Kansas Peptide compositions which induce immune tolerance and methods of use
WO1998016241A1 (en) * 1996-10-15 1998-04-23 Vanderbilt University Method of disrupting cellular adhesion
JP2002525382A (en) 1998-09-25 2002-08-13 イーサム リサーチ ディベロップメント カンパニー オブ ザ ヘブリュー ユニバーシティー オブ エルサレム Short peptides that modulate the activity of protein kinase selectively
WO2000062791A1 (en) * 1999-04-21 2000-10-26 Hisamitsu Pharmaceutical Co., Inc. D-form polypeptide which induces immune tolerance and methods of use
US6663863B2 (en) 2000-03-17 2003-12-16 Millennium Pharmaceuticals, Inc. Method of inhibiting stenosis and restenosis
KR20030051882A (en) * 2000-11-28 2003-06-25 제넨테크, 인크. Lfa-1 antagonist compounds
US20040127416A1 (en) * 2002-11-15 2004-07-01 Massia Stephen P. Therapeutic bioconjugates
WO2004094468A3 (en) * 2003-04-23 2005-03-24 Hansa Medical Res Ab Method for identifying an anti-streptococcal agent and its use for treating streptococcal infections
EP1682537B1 (en) 2003-11-05 2012-03-28 SARcode Bioscience Inc. Modulators of cellular adhesion
EP1881823B1 (en) 2005-05-17 2014-12-03 SARcode Bioscience Inc. Compositions and methods for treatment of eye disorders
US20090257957A1 (en) * 2008-04-15 2009-10-15 John Burnier Aerosolized LFA-1 antagonists for use in localized treatment of immune related disorders
WO2009128932A1 (en) * 2008-04-15 2009-10-22 Sarcode Corporation Delivery of lfa-1 antagonists to the gastrointestinal system
US8080562B2 (en) 2008-04-15 2011-12-20 Sarcode Bioscience Inc. Crystalline pharmaceutical and methods of preparation and use thereof
CN102056485A (en) * 2008-04-15 2011-05-11 萨可德公司 Topical LFA-1 antagonists for use in localized treatment of immune related disorders
US8378105B2 (en) 2009-10-21 2013-02-19 Sarcode Bioscience Inc. Crystalline pharmaceutical and methods of preparation and use thereof
US9085553B2 (en) 2012-07-25 2015-07-21 SARcode Bioscience, Inc. LFA-1 inhibitor and methods of preparation and polymorph thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988006592A1 (en) * 1987-02-26 1988-09-07 Dana-Farber Cancer Institute, Inc. Cloning of lfa-1
US4935234A (en) * 1987-06-11 1990-06-19 Dana-Farber Cancer Institute Method of reducing tissue damage at an inflammatory site using a monoclonal antibody
US4797277A (en) * 1987-09-22 1989-01-10 Pharmacia Ab Method for reperfusion therapy
JPH0276898A (en) * 1988-03-18 1990-03-16 Univ Rockefeller Method and formulation for inhibiting binding of polymorphonuclear leucocyte to endodermis and fibrinogen
US5147637A (en) * 1988-06-07 1992-09-15 The Rockefeller University Method of inhibiting the influx of leukocytes into organs during sepsis or other trauma
CA2000048A1 (en) * 1988-10-03 1990-04-03 Edward F. Plow Peptides and antibodies that inhibit integrin-ligand bindin g
US5002873A (en) * 1989-03-17 1991-03-26 Fred Hutchinson Cancer Research Center DNA sequence encoding a lymphocyte adhesion receptor for high endothelium
JPH05500504A (en) * 1989-09-27 1993-02-04

Also Published As

Publication number Publication date Type
US5340800A (en) 1994-08-23 grant
WO1992003473A1 (en) 1992-03-05 application
CA2090427A1 (en) 1992-02-28 application
EP0546077A1 (en) 1993-06-16 application

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