JPH06327412A - Growth-promoting or improving feed and method - Google Patents

Growth-promoting or improving feed and method

Info

Publication number
JPH06327412A
JPH06327412A JP5144345A JP14434593A JPH06327412A JP H06327412 A JPH06327412 A JP H06327412A JP 5144345 A JP5144345 A JP 5144345A JP 14434593 A JP14434593 A JP 14434593A JP H06327412 A JPH06327412 A JP H06327412A
Authority
JP
Japan
Prior art keywords
egg
cabbage
mugwort
animal
pears
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP5144345A
Other languages
Japanese (ja)
Inventor
Seiichi Araki
誠一 荒木
Mamoru Suzuki
護 鈴木
Masatoshi Fujimoto
昌俊 藤本
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai Co Ltd
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Priority to JP5144345A priority Critical patent/JPH06327412A/en
Priority to TW082108253A priority patent/TW391878B/en
Priority to DE69329769T priority patent/DE69329769D1/en
Priority to EP93307988A priority patent/EP0592220B1/en
Priority to US08/333,079 priority patent/US5556624A/en
Publication of JPH06327412A publication Critical patent/JPH06327412A/en
Priority to US08/433,312 priority patent/US5556625A/en
Priority to US08/438,503 priority patent/US5628998A/en
Priority to US08/438,494 priority patent/US5624671A/en
Pending legal-status Critical Current

Links

Classifications

    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/80Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management
    • Y02A40/81Aquaculture, e.g. of fish
    • Y02A40/818Alternative feeds for fish, e.g. in aquacultures

Abstract

PURPOSE:To provide a growth-promoting or improving feed safe to human and animal and provide a process for the production of the feed. CONSTITUTION:The objective growth promoting agent, animal feed or agent for improving egg-laying rate, egg weight, egg quality or shell strength contains two or more components selected from TOGENASHI (a kind of pear), mugwort and cabbage. The growth promoting agent, animal feed and agent for improving egg-laying rate, egg weight, egg quality or shell strength is producible at a low cost, has high safety and little bad influence and is effective for promoting the growth or improving the egg-laying rate, egg weight, egg quality or shell strength.

Description

【発明の詳細な説明】Detailed Description of the Invention

【0001】[0001]

【産業上の利用分野】本発明は、動物の発育促進剤、
動物用飼料、動物の発育促進方法、動物の産卵
率、卵重、卵質若しくは卵殻強度の改善剤、及び、動
物の産卵率、卵重、卵質若しくは卵殻強度の改善方法に
関する。
The present invention relates to an animal growth promoter,
The present invention relates to an animal feed, a method for promoting animal growth, an agent for improving the egg laying rate, egg weight, egg quality or egg shell strength of animals, and a method for improving the egg laying rate, egg weight, egg quality or egg shell strength of animals.

【0002】[0002]

【従来の技術】従来、動物用飼料を調整する際には、各
種の抗生物質を飼料中に添加配合したり、蛋白質を多く
飼料中に配合したり、更には給飼方法、飼料の剤形改善
など動物の飼料効率の改善や発育を促進させるなどの試
みが広く行われている。
2. Description of the Related Art Conventionally, when preparing animal feed, various kinds of antibiotics have been added to the feed, a large amount of protein has been added to the feed, the feeding method, and the dosage form of the feed. Attempts have been widely made to improve the feed efficiency of animals and improve their growth.

【0003】しかし、抗生物質の使用は、動物の体内へ
の残留や蓄積などに起因する生体に与える影響や、耐性
菌の発現に起因して、更に強力な抗生物質の投与などの
点で安全性に対する問題が指摘されている。また抗生物
質が投与された動物の排出物などによる環境汚染の問題
もある。更に、給飼方法、飼料の剤形改善などでは効果
に限界がある。そこで、安全で、弊害の少ない動物の発
育促進剤、飼料、及び、産卵率、卵重、卵質若しくは卵
殻強度の改善剤が要望されている。
However, the use of antibiotics is safe from the viewpoint of the effects on the living body due to residual or accumulation in the body of animals, and the administration of stronger antibiotics due to the development of resistant bacteria. Problems with sex have been pointed out. There is also a problem of environmental pollution due to the excrement of animals administered with antibiotics. Furthermore, there is a limit to the effect in terms of feeding method and improvement of feed formulation. Therefore, there is a demand for a safe growth-promoting agent for animals, a feed, and an agent for improving the egg laying rate, egg weight, egg quality or egg shell strength.

【0004】[0004]

【発明が解決しようとする課題】本発明は、前述のよう
な従来の飼料が有する欠点を解決した飼料及びそれを動
物に施す方法を提供することにある。
SUMMARY OF THE INVENTION It is an object of the present invention to provide a feed which solves the above-mentioned drawbacks of conventional feeds and a method of applying the same to animals.

【0005】[0005]

【課題を解決するための手段】本発明者らは、このよう
な状況に鑑みて種々検討した結果、刺梨単独、または、
刺梨、ヨモギ及びキャベツから選ばれる2種以上を組み
合わせて投与すると意外にも、その胎児を含めた動物の
発育を促進することを見出し、さらに、鳥類及び魚類に
おいては、その産卵率、卵重、卵質若しくは卵殻強度の
改善をも促進することを見出した。
Means for Solving the Problems As a result of various investigations in view of such a situation, the present inventors have found that pears alone or
Surprisingly, it was found that administration of a combination of two or more selected from prickly pears, mugwort and cabbage promotes the development of animals including the fetus, and in birds and fish, its spawning rate and egg weight. , And also promoted improvement of egg quality or eggshell strength.

【0006】本発明においては、刺梨単独、または、刺
梨、ヨモギ及びキャベツから選ばれる2種以上を組み合
わせたものを有効成分として動物に投与する。動物に投
与する際には、刺梨、ヨモギ及びキャベツ自体をそのま
ま投与してもよいし、常法により飼料に添加してもよ
い。これにより後述のごとく動物の発育(成長)を促進
するほか、飼料に添加することにより育成率または飼料
要求率を改善することができ、また、鳥類及び魚類の場
合は、その産卵率、卵重、卵質若しくは卵殻強度の改善
を促進する。したがって、本発明の目的は、新規な動物
の発育促進剤、飼料及びそれを動物に施す方法、及び、
産卵率、卵重、卵質若しくは卵殻強度の改善剤及びそれ
を動物に施す方法を提供することにある。
[0006] In the present invention, pears alone or a combination of two or more selected from pears, mugwort and cabbage is administered to animals as an active ingredient. When administered to animals, prickly pears, mugwort and cabbage itself may be administered as they are, or may be added to the feed by a conventional method. As described below, in addition to promoting animal development (growth), addition to feed can improve the growth rate or feed requirement rate. In the case of birds and fish, their egg-laying rate and egg weight can be improved. , Promotes improvement of egg quality or eggshell strength. Therefore, an object of the present invention is to provide a novel animal growth promoter, feed and method for applying it to an animal, and
(EN) It is intended to provide an agent for improving the egg laying rate, egg weight, egg quality or egg shell strength, and a method for applying the same to animals.

【0007】本発明における発育促進とは、発育改善、
胎児の発育促進をも含めた意味であり、産卵率、卵重、
卵質若しくは卵殻強度の改善とは、産卵率の向上、卵重
の増加、卵殻強度、卵質の向上を意味する。
Growth promotion in the present invention means growth improvement,
It also includes the promotion of fetal development, including egg production rate, egg weight,
The improvement of egg quality or egg shell strength means improvement of egg laying rate, increase of egg weight, improvement of egg shell strength and egg quality.

【0008】本発明で使用される刺梨は、もともと中国
貴州産のバラ科の多年生灌木植物である。また、その果
実がジュース、ジャム及び酒等の素材として注目されて
いる。刺梨の果実は薬理作用を有することが知られてお
り、防癌効果、コレステロール低下作用及び抗ストレス
作用に基づく抗潰瘍等に有用であるといわれている。
The pear used in the present invention is a perennial shrub plant of the family Rosaceae originally from Guizhou, China. In addition, the fruit has been attracting attention as a material for juice, jam, liquor and the like. The pears fruits are known to have a pharmacological action, and are said to be useful for antiulcer and the like due to their cancer-preventing effect, cholesterol-lowering effect and anti-stress effect.

【0009】本発明は詳しくは、動物の増体重促進、育
成率又は飼料要求率改善効果を有する発育促進剤、育成
率、産卵率、卵重、卵質、卵殻強度又は飼料要求率の改
善剤及び動物用飼料を提供することにある。
More specifically, the present invention relates to a growth promoter having an effect of promoting weight gain of animals, improving a breeding rate or a feed requirement rate, an agent for improving a breeding rate, an egg laying rate, an egg weight, egg quality, egg shell strength or a feed requirement rate. And to provide animal feed.

【0010】つまり本発明は、刺梨、ヨモギ及びキャベ
ツよりなる群より選択された2種以上の組み合わせより
なる動物の発育促進剤、動物用飼料、及び、産卵率、卵
重、卵質若しくは卵殻強度の改善剤である。また、刺
梨、ヨモギ及びキャベツを含有する動物の発育促進、動
物用飼料、及び、産卵率、卵重、卵質若しくは卵殻強度
の改善剤である。さらに、刺梨を含有する動物の発育促
進剤、改善飼料、及び、産卵率、卵重、卵質若しくは卵
殻強度の改善剤である。
That is, the present invention provides an animal growth promoter, a feed for animals, which comprises a combination of two or more kinds selected from the group consisting of pears, mugwort and cabbage, and the egg production rate, egg weight, egg quality or eggshell. It is a strength improver. Further, it is an agent for promoting the growth of animals containing prickly pears, mugwort and cabbage, animal feed, and an agent for improving the egg laying rate, egg weight, egg quality or shell strength. Further, it is a growth promoting agent for animals containing prickly pears, an improved feed, and an agent for improving egg laying rate, egg weight, egg quality or egg shell strength.

【0011】また本発明は、刺梨、ヨモギ及びキャベツ
よりなる群より選択された2種以上の組み合わせをその
まま、あるいは飼料に添加して動物に施すことを特徴と
する、動物の発育促進方法、及び、産卵率、卵重、卵質
若しくは卵殻強度の改善方法であり、刺梨、ヨモギ及び
キャベツをそのまま、あるいは飼料に添加して動物に施
すことを特徴とする、動物の発育促進方法、及び、産卵
率、卵重、卵質若しくは卵殻強度の改善方法である。さ
らに、刺梨をそのまま、あるいは飼料に添加して動物に
施すことを特徴とする、動物の発育促進方法、及び、産
卵率、卵重、卵質若しくは卵殻強度の改善方法である。
The present invention also provides a method for promoting the growth of animals, which comprises applying a combination of two or more kinds selected from the group consisting of prickly pears, mugwort and cabbage as they are or by adding them to the feed to the animals. And, a method of improving egg laying rate, egg weight, egg quality or egg shell strength, wherein pears, mugwort and cabbage are applied to the animal as they are or added to the feed, and a method for promoting animal growth, and It is a method for improving the egg laying rate, egg weight, egg quality, or egg shell strength. Furthermore, there is a method for promoting animal growth, and a method for improving egg laying rate, egg weight, egg quality, or egg shell strength, which comprises applying pears as they are or by adding them to feed.

【0012】本発明を実施する際、刺梨はその果実を用
いるが、その形態は特に限定されず、果実を生のまま用
いることができるし、あるいは通常用いられる方法によ
り、乾燥粉末状に用いることもできる。また、水、有機
溶剤または水と有機溶剤の混合物により抽出した有効成
分を含むエキスなどとしても用いることができる。
When practicing the present invention, the pears use the fruit thereof, but the form thereof is not particularly limited, and the fruit can be used as it is, or it can be used in a dry powder form by a commonly used method. You can also It can also be used as an extract containing the active ingredient extracted with water, an organic solvent or a mixture of water and an organic solvent.

【0013】有機溶剤としては、例えばメタノール、エ
タノール、n−プロパノール、n−ブタノール、アセト
ン、酢酸エチル、エーテル、塩化メチレン、クロロホル
ム、ベンゼン、四塩化炭素、石油エーテル等が使用さ
れ、これらの有機溶剤は1種または2種以上の混合物と
して用いることができる。
As the organic solvent, for example, methanol, ethanol, n-propanol, n-butanol, acetone, ethyl acetate, ether, methylene chloride, chloroform, benzene, carbon tetrachloride, petroleum ether, etc. are used. Can be used alone or as a mixture of two or more.

【0014】具体的な製造としては、丸善製薬株式会社
より販売されている商品名、刺梨エキスパウダーMF
(刺梨エキス30%、デキストリン70%品)を刺梨エ
キスとして用いることもできる。
[0014] As a specific manufacturing method, the brand name, Pear extract powder MF, sold by Maruzen Pharmaceutical Co., Ltd.
(Pear extract 30%, dextrin 70%) can also be used as a pear extract.

【0015】また、本発明で使用されるヨモギはキク科
の植物であり、止瀉薬、抗腹痛薬及び止血薬などの用途
が知られ、更に、グラム陽性菌にのみ弱い抗菌作用があ
ることが知られ、キャベツはアブラナ科の植物であり、
食用に用いられている。
The mugwort used in the present invention is a plant of the Asteraceae family, and is known to be used as an antidiarrheal drug, an anti-abdominal pain drug and a hemostatic drug, and further, it has a weak antibacterial effect only on Gram-positive bacteria. Known, cabbage is a plant of the Brassicaceae family,
It is used for food.

【0016】本発明を実施する際、ヨモギ及びキャベツ
は、その葉を用いるが、その形態は特に限定されず、葉
を生のまま用いることができるし、あるいは通常用いら
れる方法により乾燥粉末状として用いることができる。
また、水、有機溶剤または水と有機溶剤の混合物により
抽出した有効成分を含むエキスとしても用いることがで
きる。
In the practice of the present invention, the leaves of mugwort and cabbage are used, but the form is not particularly limited, and the leaves can be used as they are, or can be made into a dry powder form by a commonly used method. Can be used.
It can also be used as an extract containing the active ingredient extracted with water, an organic solvent, or a mixture of water and an organic solvent.

【0017】これらのエキスはそのまま、濃縮、希釈、
乾燥、または、溶剤を除去して用いられる。
These extracts are directly concentrated, diluted,
It is used by drying or by removing the solvent.

【0018】例えば、生の原料1重量部に対し水5重量
部に浸漬し、30分間煮沸熱抽出後、得られた溶液を
3.6重量部になるまで加熱濃縮することにより、エキ
スが得られる。そして、このエキスを噴霧乾燥、凍結乾
燥、減圧乾燥(真空濃縮)等により、粉末化することが
できる。
For example, an extract is obtained by immersing 5 parts by weight of water in 1 part by weight of raw material, boiling and extracting for 30 minutes, and concentrating the resulting solution by heating to 3.6 parts by weight. To be Then, the extract can be pulverized by spray drying, freeze drying, reduced pressure drying (vacuum concentration) or the like.

【0019】本発明における刺梨の使用量は、投与する
形態及び投与される動物等によって異なるため特に限定
されない。
The amount of pears used in the present invention is not particularly limited because it depends on the form of administration and the animal to which it is administered.

【0020】例えば、刺梨エキスを豚等の家畜に投与す
る場合には、通常、体重1Kg当たり刺梨エキス10mg以
上であり、好ましくは50mg以上、更に好ましくは10
0mg以上である。
For example, when the prickly pear extract is administered to domestic animals such as pigs, the prickly pear extract is usually 10 mg or more, preferably 50 mg or more, and further preferably 10 per 1 kg of body weight.
It is 0 mg or more.

【0021】さらに、本発明における刺梨とヨモギ及び
キャベツの配合比は特に限定されないが、通常、刺梨エ
キス1重量部に対し生のヨモギの葉重量に換算して0.
25〜400重量部及びキャベツの葉重量に換算して
0.5〜800重量部であり、好ましくはヨモギ0.5
〜200重量部及びキャベツ1〜400重量部、更に、
好ましくはヨモギ1〜100重量部及びキャベツ5〜2
00重量部である。
Further, the mixing ratio of the prickly pear, mugwort and cabbage in the present invention is not particularly limited, but usually, it is 0.
25 to 400 parts by weight and 0.5 to 800 parts by weight in terms of cabbage leaf weight, and preferably 0.5 mugwort.
~ 200 parts by weight and cabbage 1 to 400 parts by weight,
Preferably 1 to 100 parts by weight of mugwort and 5 to 2 of cabbage.
It is 00 parts by weight.

【0022】飼料に刺梨単独、または、刺梨、ヨモギ及
びキャベツから選ばれる2種以上を組み合わせて添加配
合して飼料を製造する場合には基礎飼料に対して少なく
とも例えば刺梨単独、または、刺梨、ヨモギ及びキャベ
ツのエキス乾燥重量として 0.001重量%以上の割合で配
合することが望ましく、さらに好ましくは 0.01 重量%
以上の割合で配合するのがよい。
In the case of producing feed by adding sashimi alone or in combination of two or more kinds selected from sashimi, mugwort and cabbage to the feed, at least for example sashimi alone or with respect to the basic feed, or The dry weight of pears, mugwort and cabbage extract is preferably added in a proportion of 0.001% by weight or more, more preferably 0.01% by weight.
It is preferable to mix the above proportions.

【0023】本発明において、刺梨単独、または、刺
梨、ヨモギ及びキャベツから選ばれる2種以上を添加す
べき動物用基礎飼料は、任意のものを使用することがで
きる。これらの基礎飼料の原料として例示されるもの
は、穀類例えばとうもろこし、マイロ、小麦粉を、そう
こう類として例えば脱脂米ぬか、ふすまを、動物質性飼
料として例えば魚粉、脱脂乳を、植物油かす類例えば大
豆油かすを、その他例えば炭酸カルシウム、リン酸カル
シウム、食塩、ビタミンB2、DLメチオニン、塩化コリ
ン、硫酸マンガン、乾燥硫酸鉄、ヨウ素酸カルシウム、
硫酸銅、乾燥硫酸亜鉛、サッカリンナトリウムなどであ
って、これらを配合して製造される。これらの原料の配
合割合は、施されるべき動物に応じて種々変更、改変さ
れる。
In the present invention, any basal feed for animals to which sashimi alone or two or more kinds selected from sashimi, mugwort and cabbage should be added may be used. Examples of the raw materials for these basic feeds include cereals such as corn, milo, and wheat flour, such as soybeans such as defatted rice bran and bran, and animal feed such as fish meal and skim milk, vegetable oil residue such as soybean oil. Dross, other such as calcium carbonate, calcium phosphate, salt, vitamin B 2, DL methionine, choline chloride, manganese sulfate, dried iron sulfate, calcium iodate,
Copper sulfate, dry zinc sulfate, sodium saccharin and the like are produced by blending these. The blending ratio of these raw materials is variously changed and modified according to the animal to be treated.

【0024】本発明の改良飼料、つまり、刺梨単独、ま
たは、刺梨、ヨモギ及びキャベツから選ばれる2種以上
を含有する飼料を施すべき動物には、家畜、家禽、ペッ
ト類、魚介類などが包含される。家畜としては豚、牛、
馬、ヤギ、羊、兎などを、家禽としては、にわとり、う
ずら、七面鳥、あひるなどを、ペット類としては犬、猫
などを、魚介類としてブリ、タイ、ヒラメ、フグ、シマ
アジ、カンパチ、サケ、コイ、ウナギ、アユ、マス、イ
ワナ、エビなどを例示することができる。
Animals to which the improved feed of the present invention, that is, pears alone or a feed containing two or more kinds selected from pears, mugwort and cabbage, are to be fed, livestock, poultry, pets, seafood and the like. Is included. As domestic animals, pigs, cows,
Horses, goats, sheep, rabbits, poultry such as chickens, quail, turkeys, ducks, pets such as dogs and cats, seafood such as yellowtail, Thailand, flounder, blowfish, horse mackerel, amberjack, salmon. , Carp, eel, sweetfish, trout, char, shrimp and the like.

【0025】[0025]

【実施例】次に実施例をあげて本発明を具体的に説明す
るが、この実施例によって本発明が限定されるものでは
ない。
EXAMPLES The present invention will now be specifically described with reference to examples, but the present invention is not limited to these examples.

【0026】生のヨモギの葉3kgを水15リットルに浸
漬し、30分間煮沸熱抽出後、得られた溶液を1.8kg
になるまで加熱濃縮し、エキスを得る。そして、このエ
キスを噴霧乾燥により粉末化し、ヨモギのエキス乾燥粉
末を得た。また、キャベツも同様に粉末化し、キャベツ
のエキス乾燥粉末を得た。そして、丸善製薬株式会社よ
り販売されている商品名、刺梨エキスパウダーMF(刺
梨エキス30%、デキストリン70%品)を1500
g、そして前記ヨモギのエキス乾燥粉末675g、キャ
ベツのエキス乾燥粉末225gを混合し、刺梨、ヨモギ
及びキャベツのエキス混合粉末2400gを得た。
3 kg of raw mugwort leaves were dipped in 15 liters of water and subjected to boiling heat extraction for 30 minutes, and then 1.8 kg of the resulting solution
Concentrate by heating until to obtain an extract. Then, this extract was powdered by spray drying to obtain a dry extract of mugwort. Further, cabbage was similarly pulverized to obtain a cabbage extract dry powder. And the brand name, Pear Extract Powder MF (30% Pear Extract, 70% Dextrin) sold by Maruzen Pharmaceutical Co., Ltd. is 1500
g, and 675 g of the dried extract of mugwort and 225 g of the dried powder of cabbage extract were mixed to obtain 2400 g of mixed powder of pear, mugwort and cabbage extract.

【0027】[0027]

【試験例】さらに試験例によって、本発明の効果を具体
的に説明する。以下の試験例では、上記実施例で製造し
た刺梨、ヨモギ及びキャベツエキス乾燥粉末、つまり重
量比で2:3:1で混合したものを用いた。また、表
2、4、10においては、χ2 検定、表6、8において
はt検定を行い、表中の「*」および「**」は各々危
険率p<0.05およびp<0.01を表す。ただし、本発明は
これらの実施例に限定されるものではない。
[Test Examples] Further, the effects of the present invention will be specifically described with reference to test examples. In the following test examples, the dried pears, mugwort and cabbage extract dry powders produced in the above examples, that is, mixed in a weight ratio of 2: 3: 1 were used. In addition, in Tables 2, 4, and 10, the χ 2 test was performed, and in Tables 6 and 8, the t-test was performed, and “*” and “**” in the tables represent risk rates p <0.05 and p <0.01, respectively. . However, the present invention is not limited to these examples.

【0028】(試験例1)健康豚( 3.0〜3.5 kg:約10
日令の去勢豚)40頭を用い、刺梨、ヨモギ及びキャベツ
投与区3群(各10頭)および刺梨、ヨモギ及びキャベツ
無添加の通常の基礎飼料の対照区(10頭)の4群に分け
た。刺梨、ヨモギ及びキャベツ投与区は、0.03、0.1 お
よび 0.3重量%の割合で刺梨、ヨモギ及びキャベツを配
合した改良飼料を30日間与えた。30日後の改良飼料摂取
量と増体重とを測定し、育成率および飼料要求率(飼料
摂取量/増体重)の算出を行ない、対照区と比較した。
(Test Example 1) Healthy pigs (3.0 to 3.5 kg: about 10
40 groups of day old castrated pigs), 4 groups of pears, mugwort and cabbage administration group 3 groups (10 each) and a control group of normal basic feed without pears, mugwort and cabbage added (10 animals) Divided into The pears, mugwort and cabbage were fed with the improved feed containing pears, mugwort and cabbage in the proportions of 0.03, 0.1 and 0.3% by weight for 30 days. After 30 days, the improved feed intake and the body weight gain were measured, and the growth rate and the feed requirement rate (feed intake / weight gain) were calculated and compared with the control group.

【0029】子豚用の人工乳基礎飼料は表1に示すとお
りである。
The artificial milk basic feed for piglets is as shown in Table 1.

【0030】[0030]

【表1】 [Table 1]

【0031】刺梨、ヨモギ及びキャベツ投与区と対照区
との比較結果を表2に示す。また、増体重に関し対照区
と投与区の間でt検定を行った。
Table 2 shows the results of comparison between the pears, mugwort and cabbage administration groups and the control group. In addition, t-test was performed between the control group and the administration group for weight gain.

【0032】[0032]

【表2】 [Table 2]

【0033】刺梨、ヨモギ及びキャベツ投与区は、対照
区と比較して、1頭当たりの増体重が大きく、飼料要求
率及び育成率の改善が見られた。
In the pears, mugwort and cabbage administration groups, the weight gain per animal was large and the feed requirement rate and the breeding rate were improved as compared with the control group.

【0034】(試験例2)生後7日令前後のホルスタイ
ン種雄子牛18頭を用い、刺梨、ヨモギ及びキャベツ投与
区2群(各6頭)及び刺梨、ヨモギ及びキャベツ無添加
の対照区(6頭)の3群に分けた。刺梨、ヨモギ及びキ
ャベツ投与区は、基礎飼料に対して 0.125および0.25重
量%の割合で刺梨、ヨモギ及びキャベツを哺乳期子牛育
成用代用乳又は哺乳期子牛育成用代用乳配合飼料(人工
乳)に混合し、20日間連続投与した。投与量として1頭
当たり 2.5g/日および5g/日となる。体重測定を試
験開始時及び試験終了時(20日後)に個体ごとに実施
し、1日当たり増体重及び増体率を算出した。
(Test Example 2) 18 Holstein male calves around the age of 7 days were used, and 2 groups (6 heads each) of pears, mugwort and cabbage were administered and a control group without addition of pears, mugwort and cabbage. They were divided into 3 groups (6 heads). In the pears, mugwort and cabbage administration groups, the pears, mugwort and cabbage were added to the basal feed at 0.125 and 0.25% by weight, respectively, with the pear, mugwort and cabbage as a milk substitute for lactating calf breeding or a mixed milk mixed feed for lactating calf breeding ( It was mixed with artificial milk) and continuously administered for 20 days. The dose will be 2.5 g / day and 5 g / day per animal. The body weight was measured for each individual at the start of the test and at the end of the test (after 20 days), and the weight gain and the weight gain rate per day were calculated.

【0035】哺乳期子牛育成用代用乳配合飼料は表3に
示すとおりである。
Table 3 shows the substitute milk-containing feed for raising calves in the lactating period.

【0036】[0036]

【表3】 [Table 3]

【0037】刺梨、ヨモギ及びキャベツ投与区と対照区
との比較結果を表4に示す。また、対照区と投与区の間
でt検定を行った。
Table 4 shows the results of comparison between the pears, mugwort and cabbage administration groups and the control group. In addition, t-test was performed between the control group and the administration group.

【0038】[0038]

【表4】 [Table 4]

【0039】刺梨、ヨモギ及びキャベツ投与区は、対照
区と比較して、1日当たりの増体重が大きく、増体率に
改善が見られた。
In the pear, mugwort and cabbage administration groups, the weight gain per day was large and the weight gain rate was improved as compared with the control group.

【0040】(試験例3)ブロイラー(チャンキー)の
雌雛を80羽用い、刺梨、ヨモギ及びキャベツ投与区(40
羽)および刺梨、ヨモギ及びキャベツ無添加の対照区
(40羽)の2区に分けた。
(Test Example 3) 80 broiler (chunky) female chicks were used, and pears, mugwort and cabbage were administered (40
Feathers) and a control group (40 birds) containing no pears, mugwort and cabbage were divided into two groups.

【0041】刺梨、ヨモギ及びキャベツ投与区は、ブロ
イラー用基礎飼料に対して刺梨、ヨモギ及びキャベツを
0.1重量%の割合で6週間与え、餌付開始時と、6週目
の体重とを測定し、卵白投与区および対照区の平均の増
体重を算出した。
The pears, mugwort, and cabbage were administered to the basal feed for broiler with pears, mugwort, and cabbage.
It was fed at a rate of 0.1% by weight for 6 weeks, the weight at the start of feeding and the weight at 6th week were measured, and the average weight gain in the egg white administration group and the control group was calculated.

【0042】ブロイラー用基礎飼料は表5に示すとおり
である。
The basic feed for broilers is as shown in Table 5.

【0043】[0043]

【表5】 [Table 5]

【0044】刺梨、ヨモギ及びキャベツ投与区と対照区
との比較結果を表6に示す。また、平均の増体重に関し
対照区と投与区の間でχ2 検定を行った。
Table 6 shows the results of comparison between the pears, mugwort and cabbage administration groups and the control group. In addition, χ 2 test was performed between the control group and the administration group for the average weight gain.

【0045】[0045]

【表6】 [Table 6]

【0046】刺梨、ヨモギ及びキャベツ投与区は、対照
区と比較して平均体重の増加で改善傾向が見られた。
In the pear, mugwort and cabbage administration groups, an improvement tendency was seen in the increase in average body weight as compared with the control group.

【0047】(試験例4)平均体重約 600gのハマチ約
12000尾を刺梨、ヨモギ及びキャベツ投与区6000尾、刺
梨、ヨモギ及びキャベツ無添加の対照区6000尾の2群に
分けた。刺梨、ヨモギ及びキャベツ投与区は、ハマチ用
基礎飼料(モイスペレット)に対して刺梨、ヨモギ及び
キャベツを 0.5重量%の割合で混和して3日間隔で1カ
月間投与し、対照区と比較した。飼育環境は縦約3m×
横約3m×深さ約3mの生簀で飼育した。給与方法は1
日当たり体重の約3%の給餌量を1日1回与えた。
Test Example 4 Hamachi with an average weight of about 600 g
The 12000 fish were divided into two groups, 6000 prickly, mugwort and cabbage administration groups, and 6000 pears, mugwort and cabbage-free control groups. The pears, mugwort, and cabbage were administered at the rate of 0.5% by weight of pears, mugwort, and cabbage to the basic feed for yellowtail (moisture pellets) and administered at intervals of 3 days for 1 month. Compared. The breeding environment is approximately 3 m long
It was bred in a cage about 3 m wide and about 3 m deep. The salary method is 1
A daily feed of about 3% of body weight was given.

【0048】ハマチ用基礎飼料は表7に示すとおりであ
る。
The basic feed for yellowtail is shown in Table 7.

【0049】[0049]

【表7】 [Table 7]

【0050】試験期間中の斃死数を刺梨、ヨモギ及びキ
ャベツ投与区と対照区で比較し、育成率改善効果につい
て検討した。結果を表8に示す。また、対照区と投与区
の間でχ2 検定を行った。
The number of deaths during the test period was compared between the pear, mugwort and cabbage administration groups and the control group to examine the effect of improving the growth rate. The results are shown in Table 8. In addition, a χ 2 test was performed between the control group and the administration group.

【0051】[0051]

【表8】 [Table 8]

【0052】刺梨、ヨモギ及びキャベツ投与区は、対照
区と比較し、斃死数が極めて少なく育成効率改善効果が
見られた。
The prickly, mugwort, and cabbage-administered groups had an extremely small number of deaths compared to the control group, and the effect of improving the growth efficiency was observed.

【0053】(試験例5)マウス・ラット用固形飼料
に、刺梨、ヨモギ及びキャベツ野外試験用製剤を、刺
梨、ヨモギ及びキャベツのエキス量として、0.01、0.0
3、0.10%添加(水懸濁液を噴霧後乾燥したもの)す
る。各群8匹のslc:SD雄性ラット21日令(体重50
〜57g)に上記刺梨、ヨモギ及びキャベツ添加飼料を1
ケ月間給与し、体重測定より、増体率を算出する。
(Test Example 5) A prickly pear, mugwort and cabbage field test formulation was added to a solid feed for mice and rats at 0.01, 0.0 as an extract amount of pear, mugwort and cabbage.
3. Add 0.10% (dried after spraying water suspension). 21-day-old male rats (body weight: 50)
~ 57 g) with the above-mentioned pear, mugwort and cabbage-added feed 1
Pay for a month and calculate the weight gain rate by weighing.

【0054】ラット用基礎飼料(固形飼料)の成分は表
9に示すとおりである。
The ingredients of the rat basic feed (solid feed) are shown in Table 9.

【0055】[0055]

【表9】 [Table 9]

【0056】試験期間中の体重を刺梨、ヨモギ及びキャ
ベツ投与区と対照区で比較し、増体重効果について検討
した。結果を表10に示す。また、対照区と投与区の間で
t検定を行った。
The body weight during the test period was compared between the pears, mugwort and cabbage administration groups and the control group to examine the effect of increasing body weight. The results are shown in Table 10. In addition, t-test was performed between the control group and the administration group.

【0057】[0057]

【表10】 [Table 10]

【0058】刺梨、ヨモギ及びキャベツ投与後は、対照
区と比較して、用量依存的に0.23〜0.53の増体率の改善
が認められた。
After the administration of pears, mugwort and cabbage, an improvement in the body weight gain of 0.23 to 0.53 was observed in a dose-dependent manner as compared with the control group.

【0059】(試験例6)デカルブTX種の鶏(182
日齢平均体重1.5Kg )を用い、各給与区8羽ずつの試験
を2回行い、その結果の平均値を表に示した。給与区を
飼料中に刺梨、ヨモギ及びキャベツのエキス0.03%添加
区、0.1%添加区、そして、無添加区の3群に分け、18
日間連続給与した。
(Test Example 6) Decarb TX chicken of the breed (182
The average daily weight of 1.5 kg) was used, and the test was conducted twice with 8 birds in each feeding group, and the average value of the results is shown in the table. The feeding area was divided into 3 groups: 0.03% added area, 0.1% added area, and non-added area of the pears, mugwort and cabbage extract in the feed.
I was paid continuously for a day.

【0060】給与終了時に、体重、卵重測定、卵質検
査、卵殻強度測定(卵殻強度計による)を行った。そし
て、飼料要求率(飼料摂取量/増体重)を算出した。
At the end of feeding, body weight, egg weight measurement, egg quality test, and eggshell strength measurement (using an eggshell strength meter) were performed. Then, the feed requirement rate (feed intake / weight gain) was calculated.

【0061】結果を表11及び12に示した。The results are shown in Tables 11 and 12.

【0062】[0062]

【表11】 [Table 11]

【0063】表11に示されているように対照区に比
べ、刺梨、ヨモギ及びキャベツ給与区では、産卵率、卵
重及び飼料要求率の向上、改善が見られた。
As shown in Table 11, in the pear, mugwort and cabbage feeding groups, the egg laying rate, egg weight and feed requirement rate were improved and improved as compared with the control group.

【0064】[0064]

【表12】 [Table 12]

【0065】表12に示されているように対照区に比
べ、刺梨、ヨモギ及びキャベツ給与区では、卵殻の厚さ
に比べ卵殻強度が向上していることがわかる。これによ
り破卵の防止が期待できる。
As shown in Table 12, in the pear, mugwort and cabbage feeding group, the eggshell strength is improved compared with the thickness of the eggshell, as compared with the control group. This can be expected to prevent egg breakage.

【0066】[0066]

【発明の効果】本発明は、刺梨を単独を、または、刺
梨、ヨモギ及びキャベツを基礎飼料中に添加して、また
はそのままの形で与えて、動物の体重増加、育成率又は
飼料要求率改善効果を有する発育促進剤、動物用飼料、
及び、産卵率、卵重、卵質若しくは卵殻強度の改善をす
る改善剤に関するものであり、刺梨、ヨモギ及びキャベ
ツを添加するので安全性が高く、環境を汚染するなどの
弊害もない。また、刺梨、ヨモギ及びキャベツは安価に
入手することができ、保存性も高い発育促進剤、動物用
飼料及び産卵率、卵重、卵質若しくは卵殻強度の改善剤
として優れたものである。
INDUSTRIAL APPLICABILITY According to the present invention, prickly pears alone, or prickly pears, mugwort and cabbage are added to the basic feed or fed as it is to give weight gain, growth rate or feed requirement of animals. Growth-promoting agent having a rate improving effect, animal feed,
Also, the present invention relates to an improving agent for improving the egg laying rate, egg weight, egg quality, or egg shell strength. Since prickly pears, mugwort and cabbage are added, the safety is high and there is no adverse effect such as environmental pollution. In addition, pears, mugwort and cabbage can be obtained at low cost and are excellent as a growth-promoting agent having a high storage stability, a feed for animals and an agent for improving egg production rate, egg weight, egg quality or egg shell strength.

Claims (12)

【特許請求の範囲】[Claims] 【請求項1】 刺梨を含有する動物の発育促進剤。1. An animal growth promoter containing pears. 【請求項2】 刺梨、ヨモギ及びキャベツより選択され
た2種以上を含有する動物の発育促進剤。
2. An animal growth promoter containing two or more kinds selected from prickly pears, mugwort and cabbage.
【請求項3】 刺梨、ヨモギ及びキャベツを含有する請
求項2記載の動物の発育促進剤。
3. The animal growth promoting agent according to claim 2, which contains pears, mugwort and cabbage.
【請求項4】 刺梨を添加した動物用飼料。4. An animal feed supplemented with pears. 【請求項5】 刺梨、ヨモギ及びキャベツより選択され
た2種以上を添加した動物用飼料。
5. An animal feed to which two or more kinds selected from sashimi, mugwort and cabbage are added.
【請求項6】 刺梨、ヨモギ及びキャベツを添加した請
求項5記載の動物用飼料。
6. The animal feed according to claim 5, wherein pears, mugwort and cabbage are added.
【請求項7】 刺梨を動物に施すことを特徴とする動物
の発育促進方法。
7. A method for promoting animal development, which comprises applying prickly pears to an animal.
【請求項8】 刺梨、ヨモギ及びキャベツより選択され
た2種以上を動物に施すことを特徴とする動物の発育促
進方法。
8. A method for promoting the growth of an animal, which comprises applying to the animal two or more species selected from pears, mugwort and cabbage.
【請求項9】 刺梨を含有する動物の産卵率、卵重、卵
質若しくは卵殻強度の改善剤。
9. An agent for improving the egg laying rate, egg weight, egg quality, or eggshell strength of a pear-containing animal.
【請求項10】 刺梨、ヨモギ及びキャベツより選択さ
れた2種以上を含有する動物の産卵率、卵重、卵質若し
くは卵殻強度の改善剤。
10. An agent for improving the egg laying rate, egg weight, egg quality, or eggshell strength of an animal, which comprises two or more kinds selected from pears, mugwort and cabbage.
【請求項11】 刺梨を動物に施すことを特徴とする動
物の産卵率、卵重、卵質若しくは卵殻強度の改善方法。
11. A method for improving the egg laying rate, egg weight, egg quality or eggshell strength of an animal, which comprises applying pricking to an animal.
【請求項12】 刺梨、ヨモギ及びキャベツより選択さ
れた2種以上を動物に施すことを特徴とする動物の産卵
率、卵重、卵質若しくは卵殻強度の改善方法。
12. A method for improving the egg laying rate, egg weight, egg quality or eggshell strength of an animal, which comprises applying two or more species selected from pears, mugwort and cabbage to the animal.
JP5144345A 1992-10-07 1993-05-25 Growth-promoting or improving feed and method Pending JPH06327412A (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
JP5144345A JPH06327412A (en) 1993-05-25 1993-05-25 Growth-promoting or improving feed and method
TW082108253A TW391878B (en) 1992-10-07 1993-10-06 Pharmaceutical composition or feedstuff comprising at least one of rosa roxburghii, artemisiae argyi folium and brassica oleracea var. capitata l.
DE69329769T DE69329769D1 (en) 1992-10-07 1993-10-07 Medicinal or animal feed containing vegetable material
EP93307988A EP0592220B1 (en) 1992-10-07 1993-10-07 Pharmaceutical composition or feedstuff containing a plant substance
US08/333,079 US5556624A (en) 1992-10-07 1994-11-01 Method of immunopotentiating and protecting an animal from E. coli infections using a combination of Rosa roxburghii, Artemisiae argyi folium and Brassica oleracea var. capitata L.
US08/433,312 US5556625A (en) 1992-10-07 1995-05-03 Pharmaceutical composition comprising Rosa roxburghii, Artemisiae argyi folium and Brassica oleracea var. capitata L. used to reduce the symptoms of diarrhea
US08/438,503 US5628998A (en) 1992-10-07 1995-05-10 Method for improving amoxicillin absorption in mammals by administering the amoxicillin to the mammal in combination with Rosa roxburghii, Artemisiae argyi folium and/or Brassica oleracea var. capitata L.
US08/438,494 US5624671A (en) 1992-10-07 1995-05-10 Method for increasing egg production rate, egg weight or eggshell strength by administering a composition containing the plants Rosa roxburghii, Artemisiae argyi folium and Brassica oleracea var. capitata L.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP5144345A JPH06327412A (en) 1993-05-25 1993-05-25 Growth-promoting or improving feed and method

Publications (1)

Publication Number Publication Date
JPH06327412A true JPH06327412A (en) 1994-11-29

Family

ID=15359955

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5144345A Pending JPH06327412A (en) 1992-10-07 1993-05-25 Growth-promoting or improving feed and method

Country Status (1)

Country Link
JP (1) JPH06327412A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100430403B1 (en) * 2001-12-07 2004-05-03 거창군 Livestock feed added with wormwood and Hanwoo meat bred by the feed
WO2009054580A1 (en) * 2007-10-24 2009-04-30 Rnl Bio Co., Ltd Composition for increasing milk production containing artemisia capillaris

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100430403B1 (en) * 2001-12-07 2004-05-03 거창군 Livestock feed added with wormwood and Hanwoo meat bred by the feed
WO2009054580A1 (en) * 2007-10-24 2009-04-30 Rnl Bio Co., Ltd Composition for increasing milk production containing artemisia capillaris
KR100904396B1 (en) * 2007-10-24 2009-06-26 주식회사 알앤엘바이오 Compositon for Increasing Milk Production Containing Artemisia capillaris
JP2010537664A (en) * 2007-10-24 2010-12-09 アールエヌエル バイオ カンパニー リミテッド Composition for increasing milk production of livestock containing wormwood

Similar Documents

Publication Publication Date Title
EP2616058B1 (en) Animal feed compositions of abscisic acid
KR101889859B1 (en) Animal feed additive having an antimicrobial and growth-promoting effect
KR950011734B1 (en) Feed and feed additive for livestock poultry and fish for increasing disease, pseudorabies resistance
US20200030269A1 (en) Animal feed compositions of abscisic acid
JP2542655B2 (en) Mixed feed for animals
George et al. Effects of graded levels of ginger (Zingiber officinale) meal as feed additive on growth performance characteristics of broiler chicks
WO2005032268A9 (en) Animal/marine feed supplement in the improvement of feed efficiency
RU2485793C2 (en) &#34;verva&#34; biologically active fodder additive
KR20210116787A (en) Composition comprising natural antibiotics spice for feed of Ptecticus tenebrifer larva, or, livestock, fish, shellfish and pet feed composition comprising the insect bred thereby
Nwokoro et al. Effect of replacement of maize with cassava peel in cockerel diets on performance and carcass characteristics
EP2817016B1 (en) Method for improving quality of poultry meat
JP3534792B2 (en) Disease resistant feed
Akinmuyisitan et al. Reproductive performance of growing female rabbits (Oryctolagus cuniculus) fed diets supplemented with cerium oxide
KR100222132B1 (en) Feed for pets
EP0153471B1 (en) Use of inosin-complexing-agents in the breeding of animals
RU2702720C1 (en) Fodder additive &#34;conifers&#34;
Hammod et al. The effect of partial replacement of maize by date pits on broiler performance
JPH06327412A (en) Growth-promoting or improving feed and method
EP4044825A1 (en) Animal feed, use thereof and method of producing said animal feed
Nurfeta et al. Effect of Tagasaste (Chymancytisus palmensis) leaf meal supplementation on feed intake, growth performance and carcass characteristics of Rhode Island Red Chicks
JP2006081530A (en) Oral administration composition for animal, and method for producing the same
JP2009247339A (en) Animal health maintaining agent, feed containing the same and rearing method
CN1759720A (en) Feedstuff additive of aloe
Irwani et al. Feed Intake and Feed Conversion Ratio of Broiler Supplemented with Herb Extract
Krzykawski et al. Effect of drinking water supplementation with Macleaya cordata extract on reproductive performance of pigeons and prevalence of endoparasitic infections during the breeding season