JPH06227999A - Animal growth promoter, agent for reducing face odor and feed - Google Patents

Abstract

PURPOSE:To provide an animal growth promoter, an agent for reducing face odor, a feed additive and a feed respectively prepared by using a plant-derived substance. CONSTITUTION:An animal growth promoter and an agent for reducing face odor respectively containing a substance obtained by extracting a plant belonging to Plocamium with a solvent as the active component and a feed additive for a warm-blooded animal and a feed respectively containing the extract.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a growth promoter for animals, a faecal odor reducing agent, and feed and feed additives. It also relates to a method for promoting animal growth and a method for reducing fecal odor.

[0002]

2. Description of the Related Art The plant Yucca shi is used as a substance having an effect of promoting animal growth and an effect of reducing fecal odor.
extracts from Digera are known (eg,
Feeding, pp. 39-42, Vol. 31, Vol. 2.
No. (1991)).

[0003]

DISCLOSURE OF THE INVENTION The present inventors have conducted earnest research for the purpose of developing an animal growth promoting agent, a fecal odor reducing agent and a feed utilizing a plant-derived substance, and completed the following invention. It was

[0004]

Means for Solving the Problems The present invention is directed to an animal growth promoting agent, a fecal odor reducing agent, and a warm-blooded animal containing the extract, which comprises a solvent extract of a plant belonging to the genus Eucalyptus as an active ingredient. And feed additives for warm-blooded animals. Further, it is a method for promoting animal growth and a method for reducing fecal odor using the extract.

Examples of plants belonging to the genus Eucalyptus include Eucalyptus globulus, Eucalyptus robusta, Eucal
yptus melliodora, Eucalyptus cornuta, Eucalyptus b
eyeri, Eucalyptus deglupta. Eucalyptus dealbata, Eu
calyptus microcorys, Eucalyptus citriodora, Eucaly
ptus paniculata, Eucalyptus umbra, Eucalyptus creb
ra, Eucalyptus albens, Eucalyptus tereticornis, Eu
calyptus botryoides, Eucalyptus deanei, Eucalyptus
ovata, Eucalyptus maculata, Eucalyptus pilularis,
Eucalyptus piperita, Eucalyptus propinqua, Eucaly
ptus colossea, Eucalyptus exerta, Eucalyptus longi
folia, Eucalyptus resinifera, Eucalyptus sideroxyl
on, Eucalyptus acmenioides, Eucalyptus gomphocepha
la, Eucalyptus punctata, Eucalyptus smithii, Eucal
yptus rostrata, Eucalyptus viminalis, Eucalyptus p
urvelulenta, but Eucalyptus deglupta, E
ucalyptus citriodora is preferred. The part to be extracted is not particularly limited and may be leaves, stems, roots, etc., but leaves are preferred.

As the extraction solvent, water or a water-containing organic solvent is usually used. The hydrated organic solvent is preferably a hydrated alcohol such as hydrated methanol, hydrated ethanol, hydrated propanol or the like, a hydrated hydrophilic organic solvent such as hydrated acetone or a hydrated ketone such as hydrated methyl ethyl ketone, and more preferably hydrated methanol or hydrated acetone. These solvents may be used alone or as a mixture. The water content in the water-containing organic solvent is 1 v / v% or more, preferably 3-50 v
/ V%, more preferably about 5-30v / v%.

The extract of the present invention can be obtained, for example, by the method described below. Leaves, stems, roots, etc. of plants belonging to the genus Eucalyptus are dried at 35-80 ° C. and crushed, or
Alternatively, cut or crush as it is. The above-mentioned solvent is added to the thus obtained product, an extraction operation is carried out, and then a fraction containing the active ingredient is fractionated. Depending on the purpose of use, the extract may be used without fractionation. The extract can be used as it is or after distilling off the solvent. Alternatively, the solvent may be distilled off and then concentrated, dried or dried to be used.

If necessary, aliphatic hydrocarbons such as n-hexane, heptane and octane, alicyclic hydrocarbons such as cyclohexane, aromatic hydrocarbons such as toluene and xylene, diethyl ether, isopropyl ether and the like. It may be carried out by using a water-insoluble organic solvent such as ethers and petroleum ether, and adding an operation for removing the fat-soluble component in the plant. This operation, after adding the solvent, after performing the extraction operation, or after the extraction operation, after fractionating the fraction containing the active ingredient, the water-insoluble organic solvent was added to these extracts,
Wash and do. Alternatively, a water-insoluble organic solvent may be added to the powder after drying and pulverization before the extraction operation and washing may be performed.

The extract used in the present invention may be orally administered as it is as an animal growth promoting agent and / or faecal odor reducing agent, or may be mixed with feed to be administered. Furthermore, it may be formulated and administered. Animals to be administered include domestic animals such as pigs, cows, sheep, horses, dogs and cats, warm-blooded animals such as poultry such as chickens, turkeys, ducks and guinea fowls (excluding humans), yellowtail, Thailand, shrimp, puffer fish. , Aquacultured aquatic animals such as Japanese flounder, flounder and coho salmon. The dose of eucalyptus extract to animals is 0.1 mg / kg body weight per day.
-500 mg, preferably 1 mg-100 mg.

As the feed to which the eucalyptus extract is added,
Cereals such as corn, wheat and barley; beans such as soybeans and broad beans; potatoes such as cassava and sweet potato; soybean meal,
Vegetable oil meal such as cottonseed meal and rapeseed meal; rice cake such as rice bran and rice bran; corn gluten meal, starch meal, molasses meal, beer meal, tofu meal, etc. , Animal whey such as dried whey; yeasts such as brewer's yeast and torrula yeast; fats and oils; corn starch,
Glucose and other saccharides; other feeds that can be used as feed ingredients, and feeds containing one or more types thereof are included.
In particular, feed for livestock and poultry is preferable. In addition to these feeds, feed additives such as vitamins, amino acids, minerals and antibacterial agents can be added.

When the eucalyptus extract is used as a feed additive, the amount added to the feed is 0.001-5%, preferably 0.01-1%. For the addition to the feed, the eucalyptus extract may be added as it is, but normally, rice bran, bran, soybean meal, calcium carbonate, chaff, powdered lactose,
It is preferable that the extract content is about 0.5 to 50% with an excipient such as wheat flour and corn starch, and then added.

The eucalyptus extract is formulated by a well-known method by adding known additives such as an excipient, a binder, a disintegrating agent, a lubricant, a stabilizer, and a miso flavoring agent to the extract. be able to. Formulation Example 1 (Formulated feed) Eucalyptus extract 0.1 Kg and yellow corn 65.7
Kg, bran 10 kg, defatted rice bran 7.5 kg, soybean meal 6.5 kg, fish meal 5 kg, alfalfa meal 3 K
g, calcium carbonate 1.7 Kg, salt 0.3 Kg, trace mineral mixture 0.05 Kg, vitamin ADE mixture 0.05 Kg, vitamin B group mixture 0.1 Kg were mixed for 20 minutes with an okado type feed mixer, and mixed feed for livestock 100
Obtain Kg. Formulation Example 2 (Feed Additive) 2 Kg of eucalyptus extract and 18 Kg of defatted rice bran are mixed for 15 minutes with a V-type mixer to obtain 20 Kg of the formulation.

The extract used in the present invention can be administered orally in the form of tablets, capsules, granules, powders or syrups directly or added to the feed.

[0014]

[Action]

(Experimental example) 1. Sample Preparation Dry leaves (1600 g) of Eucalyptus citriodora were mixed with water (1000 ml) and acetone (70 ml).
00 ml) was added and the mixture was circulated with stirring for 2 hours. This was filtered or decanted, and acetone and a water extract (4000 ml) were taken out. Aqueous acetone containing 10% water (4000 ml) was added to the extraction residue, and the mixture was stirred at room temperature for 2 hours.
It was circulated with stirring for a time. From this, an acetone and water extract (4000 ml) was taken out again. Finally, once again, this extraction residue contained 10% water in water containing acetone (4
000 ml) was added, and the mixture was circulated with stirring at room temperature for 2 hours, and then an acetone and water extract (4900 ml) was taken out again. Combine the extracts 3 times (12900m
l), bath temperature 70 ° C, acetone (6300 ml) at normal pressure
Was distilled off. The residual liquid (6600 ml) was added to hexane (66
(00 ml) was added, the mixture was placed in a separating funnel, shaken well, and then allowed to stand to remove the hexane layer. Fresh hexane (1320 ml) was added to the residual liquid, and the mixture was thoroughly shaken again and allowed to stand still to remove the hexane layer. The residual liquid (3000 ml) was concentrated under reduced pressure at a bath temperature of 70 to 75 ° C. and dried to obtain 191.1 g of a dried product.

2. Experimental method Using a 4-day-old broiler female chick (Arbor acre), a feeding test was performed for 16 days. The sample was added to the feed having the following composition in an amount of 0.1% and fed to broiler female chicks. During the test period, the body weight and the feed intake were measured, the weight gain and the feed requirement rate were calculated, and the growth promoting effect was confirmed. Regarding the deodorizing effect, feces were collected at the end of the test, and the intensity of fecal odor was examined by a sensory test by panelists. The group to which the feed without feed was given was used as a control. Feed composition Ingredient name Broiler Early feed (%) Yellow corn 65.1 Soybean meal 23.5 Fishmeal 6 Alphafaral 3 Calcium carbonate 0.6 Dicalcium phosphate 0.4 Salt 0.4 Mineral 0.1 Vitamin ADE 0. 1 Vitamin B group 0.2 L-lysine 0.25 DL-methionine 0.25 choline chloride 0.1 total 100.0

3. Results The results of the growth promoting action are shown in Table 1, and the results of the fecal reducing action are shown in Table 2.

[Table 1]

[Table 2]

As is clear from these tables, the eucalyptus extract-administered group gained more body weight than the non-administered control group, while the feed conversion rate was low and the growth-promoting effect was low. It is good. The fecal odor is also reduced. No toxicity was observed.

[0018]

As is apparent from the above, the present invention provides a new animal growth promoter and faecal odor reducing agent.

 ─────────────────────────────────────────────────── ─── Continuation of the front page (72) Inventor Yasuo Fujii 6-6 Honmachi, Ageo City, Saitama Prefecture 10-302 Ageo Higashi Complex 10-302 (72) Inventor Shoichi Kato 309-2 Square House, Ageo City, Saitama Prefecture (72) Invention Takeshi Watanabe 1241-1 Tomuro, Atsugi City, Kanagawa Prefecture Genesta Kazawa 102

Claims (6)

[Claims] 1. An animal growth promoter comprising a solvent extract of a plant belonging to the genus Eucalyptus as an active ingredient. 2. An animal fecal odor reducing agent comprising a solvent extract of a plant belonging to the genus Eucalyptus as an active ingredient. 3. A method for promoting the growth of an animal, which comprises orally administering a solvent extract of a plant belonging to the genus Eucalyptus to the animal. 4. A method for reducing fecal odor in an animal, which comprises orally administering a solvent extract of a plant belonging to the genus Eucalyptus to the animal. 5. A warm-blooded animal feed containing a solvent extract of a plant belonging to the genus Eucalyptus. 6. A warm-blooded animal feed additive containing a solvent extract of a plant belonging to the genus Eucalyptus.