JPH062140Y2 - Shaking device for inspection of blood, cells, etc. - Google Patents

Description

[Detailed Description of the Invention] The present invention relates to an improvement of a shaking device for stirring a sample / specimen such as blood / cells in a state of being suspended in a reagent or a washing solution.

When inspecting a sample of collected blood, cells, etc., put the sample into a test tube and repeat the addition of reagent and washing, but the reaction with the reagent and the washing work after the reaction should be done in the test tube. Put a lid on the top opening of the, and press it with your finger from the outside of the lid,
Set the test tube in a horizontal position, shake it by shaking your hand in that position, and at the end of that process, separate and remove the reagent / washing water, add the reagent / washing water again, and repeat the same procedure. I try to repeat the process.

This is because shaking the sample in the test tube with the reagent or the washing solution is more preferable when the test tube is shaken in a horizontal position than when the test tube is held in an upright position and then shaken in a normal shaker. The effect of shaking can be improved in a short period of time, and it is necessary to add several kinds of reagents sequentially to the sample collected in one test tube, and shaking must be performed each time. This is because the operation of loading and unloading the test tube to and from the shaker is troublesome for the work.

From this, the square flat box-shaped tube rack that supports the test tubes (test tubes) vertically and horizontally on the shaking table provided on the shaker body is supported by the test tube that is erected in the standing position by the pivot. Means have been developed to rotatably support the robot so that it will lie down.

However, in this means, a tube rack in the shape of a square flat box is provided with a pressing member for pressing the lids that cover the upper end opening of each test tube aligned and supported by the tube rack to make it a sealed state. It is necessary to carry out a troublesome operation of switching the pressing members to the pressed state and the released state of the lid members plugged into the upper end opening of each test tube, and this square By rotating the whole flat box-shaped tube rack by the pivot shaft, the volume of the whole shaker becomes large, and other problems such as inconvenience in handling have arisen.

The present invention was made in order to eliminate these problems that have occurred in the conventional means, and the tube rack supported by a vibrating table that vibrates in the horizontal direction of the shaker is placed vertically and horizontally in a vertical position. It is an object of the present invention to provide a new means for easily loading and unloading test tubes while switching a large number of aligned and supported test tubes to a horizontal posture and vibrating them. .

In the present invention, as means for achieving this object, a large number of test tubes in a standing posture are arranged in a line on a vibrating table provided on the body of a shaker and reciprocating along a horizontal direction. A unit tube rack that is at least supported is arranged, and both ends of the unit tube rack in the longitudinal direction are rotatably mounted on the vibrating table by pivots along the longitudinal direction of the unit tube rack. , The test tube supported on the unit tube rack is pressed against the upper end opening of the test tube in a state in which the test tube is laid sideways due to the rotation of the unit tube rack, and the lid body that covers the upper end opening is pressed. The present invention proposes a shaking device provided with a holding member for testing blood, cells and the like.

Next, embodiments will be described in detail with reference to the drawings.

FIG. 1 is a schematic perspective view of the entire apparatus of an embodiment of the present invention. In FIG. 1, a is a machine body, b is a vibrating table which is mounted on the machine body a so as to reciprocate along a horizontal direction, and c is its body. Shaking table b
Unit tube racks, which are juxtaposed above each other, d ... Denote test tubes which are supported by the unit tube racks c aligned in the longitudinal direction thereof.

The machine body a is composed of a base board 10, a support frame 11 provided on the upper surface thereof, and a case 12 covering the upper surface side, and is formed in a base box shape. And, on the upper surface side of its base 10, a reciprocating motion including a motor M for reciprocating a vibrating table b supported by a support frame 11, a crank wheel 20 driven by the motor M, and a reciprocating rod 21 connected thereto. Mechanism 2 is provided.

The vibrating table b is mounted on a support frame 11 provided on the upper surface side of the table 10, and is mounted on a guide rod 110, 110 in the front-rear direction (the direction of the arrow in FIG. 2). By fitting the fitting parts 30 provided on the above-mentioned part in a slidable manner, the supporting part 11 is movably supported in the front-rear direction on the support frame 11, and the connection provided at the left and right center parts on the lower surface side. Member 31
Is connected to the reciprocating mechanism 2 described above, and the reciprocating mechanism 2 is driven by the operation of the motor M, so that the guide rod 1
It reciprocates back and forth along 10 ・ 110.

The vibrating table b is formed in the shape of a flat box having a peripheral wall on the peripheral edge thereof, and the peripheral walls 32, 32 on the left and right sides thereof are
The axis e for pivotally supporting the unit tube rack c, which has the axial direction as the left-right direction, is axially supported in parallel in the front-rear direction at a slightly wider interval than the width of the unit tube rack c on the left and right. is there. The peripheral wall 32 of the pivots e ...
A fitting member f formed in the shape of a rectangular piece is integrally fixed to the inner end portion projecting inward so as to rotate along the inner surface of the peripheral wall 32 by the rotation of the pivot shaft e around the pivot shaft e. (Fig. 5). Further, as shown in FIG. 3 and FIG. 4, turning arms 33, which are long in the vertical direction, are integrally assembled to the outer end portions of the outer peripheral side of the peripheral wall 32 of the pivot shaft e, respectively. . The rotary arms 33 are connected to the vibrating table b by the connecting shafts 34 provided at their respective rotary ends.
It is connected to the operating member 4 provided in the front-back direction.

As shown in FIGS. 3 and 4, the operating member 4 is arranged on the outer surface side of one of the left and right peripheral walls 32 of the vibrating table b (the right peripheral wall 32 in the illustrated example). The connecting plate 40 that is long in the front-rear direction, and the upper and lower shaft tubular portions 41.4 that are installed at an intermediate portion of the connecting plate 40 in the front-rear direction.
1, the operating shafts 42, 42 slidably fitted in the shaft tubular parts 41, 41, and the upper ends of the operating shafts 42, 42, and the upper end of the peripheral wall 32 of the vibrating table b. It comprises an actuating part 43 movably supported in the front and rear direction on a brim-shaped sliding base 35 formed on the part. The rotating arms 33 attached to the outer ends of the above-mentioned pivots e ... In the state where they are aligned in parallel as shown in FIG.
By connecting the respective rotary ends to the connecting plate 40 by the connecting shaft 34, they are connected to the operating member 4. Further, an appropriate rotating arm 33 among the rotating arms 33 arranged in front and rear (the rotating arm 33 on the front end side in the illustrated example).
Between the connecting plate 40 and the connecting plate 40, as shown by a solid line in FIG. 4, a state in which the rotating arm 33 is rotated backward to the center of the pivot axis e is shown by an imaginary line in FIG. In the state where the spring 36 is rotated forward, springs 36 are stretched so as to switch the biasing direction beyond the dead center. As a result, when the actuating member 4 is pushed backward (to the right in FIG. 4), the rotary arms 33 ... Are in the solid line state in FIG. 4, and when the actuating member 4 is pulled toward you, the rotary arms 33. Is the axis e
It is arranged to switch to the state of the imaginary line in FIG.

In the unit tube rack c, as shown in FIG. 6, the width of the machine wall of the four circumferences is somewhat shorter than the length of the test tube d, and the length corresponding to the left and right widths of the inner cavity of the vibrating table b. It is shaped like a continuous rectangular tube. Then, as shown in FIG. 7, the test tube d is provided on the machine wall 50 on the upper surface side thereof.
The tube insertion holes 51 for inserting the ... Are formed in a line in the longitudinal direction, and the machine wall 52 on the bottom side is
At the portions corresponding to the tube insertion holes 51 ...
A through hole 53 having a diameter smaller than the diameter of the test tube d is formed.

As shown in FIG. 7, the unit tube rack c is provided with fitting portions 55 each having a vertical fitting groove 54, as shown in FIG. By fitting the fitting portion 55 into the piece-shaped fitting members f provided at the inner ends of the pivot shafts e supported on the left and right peripheral walls 32 of the vibrating table b described above. , Said axis e
The machine wall 50, which is supported by the vibrating table b so as to rotate around the center and has the tube insertion holes 51, is set in an upward posture so that the machine wall 50 is pulled up to come off the vibrating table b.

The pressing member 6 has a strip-plate-shaped leaf spring 60 having a length that crosses the inner cavity of the vibrating table b in the left and right directions, and as shown in FIG. The bending upper edge 62 is bent obliquely in the same direction as the lower edge 61 and is formed so that the side section has a substantially channel shape with a lateral direction, and tongue-shaped insertion pieces 63. It is configured by forming 63. Then, the pressing member 6 rotates the unit tube rack c in a state in which the test tube d is supported on the unit tube rack c supported by the vibrating table b so as to rotate about the pivots e and e. , When the supporting test tube d is in a horizontal posture as shown by the chain line in FIG. 6, the test tube d is arranged so as to face the upper end opening 70 of the test tube d, and the vibrating table b It is attached to. Then, the assembly is performed by a locking member g mounted on each inner surface of the left and right peripheral walls 32 of the vibrating table b.
The engaging groove 64 is provided in the engaging groove 64, and the tongue-shaped insertion piece 63 provided in each of the longitudinal ends of the pressing member 6 in the engaging groove 64.
It is done by pushing the
However, it can be easily removed by pulling it up.

Next, FIG. 10 shows a modification of the mounting means for the pressing member 6.

In this embodiment, the pressing member 6 is a unit tube rack c.
A strip-shaped plate spring 60 formed to have substantially the same length as
As shown in FIG. 11 and FIG. 11, the presser foot is formed by molding so as to be continuous in the left-right direction with a shape curved in a substantially arcuate shape in a side view. The presser foot is composed of a leaf spring 60 curved in an arc shape in the side view. In a side view, the member 6 is made to face the bottom surface of each unit tube rack c so that the chord side thereof faces upward, and among the front and rear side edges continuous in the longitudinal direction of the holding member 6. The side edge located on the rear side is fixed to the rear end side of the bottom surface of the unit tube rack c for attachment.

As a result, a plurality of unit tube racks c arranged side by side in the front-rear direction are actuated by the pivoting arms 33.
When all of the unit tube racks c ... are attached to the bottom surface of the unit tube racks c.
Is located on the rear surface side of each unit tube rack c ... And the lids 72 of the test tubes d supported on the unit tube racks c located immediately behind the unit tube racks c ... As shown in FIG. 11, they are each pressed from the front side.

Also in this embodiment, the holding member 6 for holding the lids 72 of the test tubes d supported on the frontmost unit tube rack c among the unit tube racks c arranged in front and rear, When the unit tube rack c located at the foremost position is tilted forward, the unit tube rack c is placed at a position located on the front side of the lid 72 of the test tube d ... Installed in. In addition, the unit tube racks c that are arranged side by side in front and back ...
As shown in FIG. 11, the attachment of the holding member 6 is omitted on the bottom surface of the rearmost unit tube rack c.

As shown in FIG. 7, the test tube d has a configuration in which a lid 71 for opening and closing a hinge 71 is provided at the upper end opening 70.

The embodiment apparatus configured as described above operates as follows.

By inserting the test tubes d into the tube insertion holes 51 of the unit tube racks c supported by the vibrating table b and loading them, and pulling the operating member 4 toward you in that state,
A series of rotating arms 33 attached to the outer ends of the pivots e of the unit tube racks c rotate in unison, so that the unit tube racks c each have an axis extending along the longitudinal direction thereof. The test tubes d, which have been rotated 90 degrees around the center of e and supported in the upright posture, are brought into a horizontal posture as shown by the imaginary line in FIG. The outer surfaces of the lids 72 ... Attached to the upper end openings 70 of the test tubes d ...
Alternatively, the pressing member 6 mounted on the bottom surface of the unit tube rack c ... is pressed and held, and the lid body 72 that covers the upper end opening 70 is held in a sealed state.

In this state, when the motor M is operated to drive the reciprocating mechanism 2, the vibrating table b reciprocates back and forth along the guide rod 110 of the support frame 11 provided on the machine body a. Each of the unit tube racks c ... which are supported by the unit is vibrated in a direction orthogonal to its longitudinal direction, and the horizontal test tubes d ... The sample and reagents are effectively shaken.

Next, when the shaking process for a predetermined time is completed, the motor M is stopped and the above-mentioned actuating member 4 is operated so that the test tubes d supporting the respective unit tube racks c stand upright. When the test tube d is rotated in such a state, the upper end opening 70 covered by the lid 72 of the test tubes d is exposed from the holding member 6 to the upper surface side of the machine body a in that state.

As a result, the test tube d ...
You can take it out by holding it's head and pulling it up.

At this time, if the unit tube rack c is lifted up, the test tubes d ... Can be taken out completely while being loaded in the unit tube rack c.

When the test tubes d ... Taken out after a predetermined inspection process and are shaken again, they are inserted into or inserted into the tube insertion holes 51 ... of the unit tube rack c supported by the vibrating table b. The unit tube rack c that has been completed is assembled to the vibrating table b.

At this time, when the shaker A needs to be cleaned, the pressing member 6
Also remove the unit tube rack c and clean it.

As described above, the shaking device for inspecting blood, cells, etc. according to the present invention has a large number of standing postures on the shaking table b reciprocating along the horizontal direction provided on the body a of the shaking machine A. A unit tube rack c for arranging and supporting the test tubes d in a line is arranged, and both ends of the unit tube rack c in the longitudinal direction are rotatably caused by a pivot axis e whose axial direction is along the longitudinal direction. It is mounted on a stand b,
In the vibrating table b, the test tubes d supported on the unit tube rack c are located at positions facing the upper end opening 70 of the test tubes d in a state where the test tubes d are laid sideways by the rotation of the unit tube rack c. Since the pressing member 6 that presses the lid body 72 that covers the upper end opening 70 is provided, when the unit tube rack c in which the test tubes d ... Are suspended in parallel is rotated 90 degrees about the pivot axis e. While the test tubes d ... Are all in a horizontal posture at the same time, the lid body 72 that covers the upper end opening 70 is pressed by the holding member 6, and the unit tube rack c is rotated by 90 degrees after the shaking operation. And bring it up,
Since the test tubes d ... Stand up all at once and move away from the pressing member 6, a large number of tubes are supported in an upright position on a tube rack supported by a vibrating table that vibrates in the horizontal direction of the shaker. The test tube can be easily loaded and unloaded while switching to a horizontal position and vibrating.

[Brief description of drawings]

FIG. 1 is an overall perspective view of an apparatus according to an embodiment of the present invention, FIG. 2 is a perspective view of the same with the case removed, and FIG. 3 is a partially cutaway plan view of the same as above. Is a partially cutaway side view of the same as above. FIG. 5 is a vertical sectional front view of the same as above.
FIG. 7 is a vertical sectional side view of a main part of the same as above, FIG. 7 is a perspective view of a unit tube rack above, and FIG. 8 is a perspective view of a holding member above.
FIG. 9 is a perspective view of the vibrating table portion of the above, FIG. 10 is a perspective view of a portion of another embodiment, and FIG. 11 is an explanatory view of the same operation. Explanation of reference numerals A ... Shaking machine, a ... Machine body b ... Shaking table, c ... Unit tube rack d ... Test tube, e ... Axis f ... Fitting member, g ... Locking member M ... Motor, 10 ... Platform 11 ... Support frame, 12 ... Case 110 ... Guide rod, 2 ... Reciprocating mechanism 20 ... Crank wheel, 21 ... Reciprocating rod 30 ... Fitting part, 31 ... Connecting member 32 ... Peripheral wall, 33 ... Rotating arm 34 ... Connecting shaft , 35 ... Sliding base 36 ... Spring, 4 ... Actuating member 40 ... Connecting plate, 41 ... Shaft cylinder part 42 ... Actuating shaft, 43 ... Actuating part 50 ... Machine wall on the upper surface side, 51 ... Tube insertion hole 52 ... Bottom surface Side machine wall, 53 ... through hole 54 ... fitting groove, 55 ... fitting portion 6 ... pressing member, 60 ... leaf spring 61 ... lower edge, 62 ... upper edge 63 ... insert piece, 64 ... engaging groove 70 ... Top opening, 71 ... Hinge 72 ... Lid

Claims (6)

[Scope of utility model registration request] 1. A unit tube rack in which a large number of test tubes d ... Standing are aligned in a row and supported on a vibrating table b that reciprocates along a horizontal direction provided on a body a of a shaker A. c is arranged, and both end portions in the longitudinal direction of the unit tube rack c are rotatably mounted on the vibrating table b by means of a pivot axis e whose axial direction is along the longitudinal direction. The test tube d supported on the unit tube rack c is covered with the upper end opening 70 at a position facing the upper end opening 70 of the test tubes d in a state in which the test tube d is in a horizontal posture due to the rotation of the unit tube rack c. A shaking device for inspecting blood, cells, and the like, which is provided with a pressing member 6 that presses the lid body 72. 2. A unit tube rack in which a large number of test tubes d ... Standing are aligned in a row and supported on a vibrating table b that reciprocates along a horizontal direction provided in a body a of a shaker A. c are arranged side by side in the front-rear direction, and both end portions of each of the unit tube racks c ...
Is rotatably mounted on the vibrating table b, and on the vibrating table b, the front side of the unit tube rack c located at the front of the unit tube racks c arranged in front and rear of the machine body a. , A lid body that covers the upper end opening 70 of the test tube d that is supported on the unit tube rack c in a state in which the frontmost unit tube rack c is tilted forward and is opposed to the upper end opening 70. The pressing members 6 for pressing 72 are provided, and the pressing members for the test tubes d are supported by the unit tube racks c ... of the second row and below in the parallel order from the front end side of the unit tube racks c. A shaking device for inspecting blood, cells and the like, in which 6 is provided on each bottom surface of the unit tube racks c. 3. A pressing member 6 is formed on a strip-shaped spring plate 60 parallel to the unit tube rack c along the longitudinal direction of the unit tube rack c, and both ends in the longitudinal direction thereof are vibrating base b. The shaking device for inspecting blood, cells, etc. according to claim 1, which is supported by. 4. A strip-shaped spring plate 60 in which a holding member 6 provided on the bottom surface of the unit tube rack c ... Is parallel to the unit tube rack c along the longitudinal direction of the unit tube rack c.
3. The shaking device for inspecting blood, cells, etc. according to claim 2, wherein the shaking device is formed on the bottom surface of the unit tube rack c, and one side edge in the longitudinal direction thereof is fixed to the bottom surface of the unit tube rack c. 5. Fitting members f ... Which rotate integrally with the pivots e are provided at the respective inner ends of pivots e, e which pivotally support a plurality of unit tube racks c. The shaking device for inspecting blood, cells, etc. according to claim 1, wherein fitting portions 55, 55, which are provided at both ends in the longitudinal direction of each unit tube rack c, are detachably fitted. 6. A plurality of unit tube racks c ..
Unit tube racks c that are supported by
Are attached to the outer end sides of the respective pivotal shafts e ... that pivotally support the pivotal shafts e. 2. The shaking device for inspecting blood, cells, etc. according to claim 1, which is linked to an operating member 4 provided on a vibrating table b so as to move freely in a direction orthogonal to the above.