JPH06207935A - Collecting container for biomedical sample - Google Patents

Abstract

PURPOSE:To collect feces irrespective of the physical characteristics thereof even in case of loose stool, diarrhea, watery stool, etc., difficult to collect. CONSTITUTION:The container consists of a container body 8 having an opening 10 at an end thereof which can store a liquid 9 therein, a lid part 11 which can seal the opening 10 of the body 8, a collecting rod 12 penetrating closely the lid part 11 and formed of a fiber strand 15, and an upper lid part 17 designed to enclose a oozing part 14 and to be securely fixed to the lid part 11 to seal the main body. One end of the collecting rod 12 which can be dipped into the liquid 9 in the main body 8 is a collecting end 13, and the other end is the oozing part 14 projecting a predetermined length from the lid part 11.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention mainly relates to a biological sample collection container for collecting feces as a sample for detecting occult blood in feces.

[0002]

2. Description of the Related Art Conventionally, feces have been used as a sample in various tests, and the detection of occult blood in feces is extremely important for early detection of digestive system diseases, especially colon cancer. .

As conventional containers for collecting feces as samples for detecting occult blood in feces, those described in Japanese Utility Model Publication No. 64-42454, those disclosed in Japanese Utility Model Publication No. 1-66071, and Japanese Utility Model Publication No. -140468,
For example, the one described in Japanese Utility Model Publication No. 2-13977 is available.

FIG. 4 shows an example of a general stool collection container that has been conventionally used. In the stool collection container, a collection rod 2 made of plastic or the like integrated with a lid 1 is inserted into the stool. Then, the stool is attached to the collection rod 2, and then the collection rod 2 with the stool attached is inserted into the container body 3 to fix the lid portion 1 to the container body 3, and the stool is stored in the liquid inside the container body 3. 4 to obtain a stool suspension, and the stool suspension is filtered by a filter 6 through a bypass 5 formed in the lid 1 by turning the container body 3 upside down and applying pressure with a finger. Then, it has a structure in which the sample solution is supplied to the outside from the drip section 7 integrated with the lid section 1 and used for the inspection.

[0005]

However, in the stool collection container as described above, since the stool is obtained by attaching the stool to the collection rod 2 made of plastic or the like, there is a problem when the stool is in a paste form. However, in the case of loose stools, diarrhea stools, watery stools, etc., which are often seen in colorectal diseases, it is not easy to collect them with a sampling rod 2 made of plastic, etc. There was a problem that it was difficult to obtain a liquid and it was difficult to carry out an accurate inspection.

Further, it is necessary to provide a filter 6 and a bypass 5 for guiding the fecal suspension to the filter 6 as a filtering device, which causes a problem that the structure of a small fecal collection container becomes complicated. In addition, when testing large numbers of samples,
It is necessary to apply pressure to each of the container bodies 3 to take out the fecal suspension, which is a problem in efficiently performing the test.

In view of the above situation, the present invention has a simple structure and enables easy collection of stools such as soft stools, diarrhea stools, and watery stools which are difficult to collect regardless of their physical properties. It is intended to provide a biological sample collection container.

[0008]

According to the present invention, there is provided a container main body having an opening at an end and capable of accommodating a liquid, a lid portion capable of sealing the opening portion of the container main body, and the lid portion tightly sealed. A collecting rod made of a fiber bundle having one end penetrating into the container body and capable of being immersed in the liquid in the container body as a collecting end, and the other end side protruding from the lid by a required length to form a bleeding portion; and the bleeding portion And an upper lid configured to be fixed to the lid so as to surround and seal the living sample collecting container, and the collecting end of the collecting rod is formed obliquely with a required angle. The present invention relates to a biological sample collection container characterized by the above.

[0009]

[Function] Regardless of the physical properties of feces such as loose stools, diarrhea stools, and watery stools, the feces are adsorbed in the fibers of the sampling rod, and after the sampling rod is immersed in the liquid in the container body, the container body is opened. The part is sealed with a lid. It can be safely handled in this state. When performing the inspection, if the upper lid is removed, the fecal solution that is suspended and the feces are dissolved in the liquid rises the sampling rod consisting of fiber bundles due to the capillary phenomenon and exudes from the exudation part. The fecal lysate should be collected by another device at the dispensing part.

[0010]

Embodiments of the present invention will be described below with reference to the drawings.

1 to 3 show one embodiment of the present invention,
In the figure, 8 is a container body capable of containing a liquid 9 such as saline or a buffer solution for suspending feces, the container body 8 has a cylindrical shape, and an opening 10 is provided at an end thereof. A lid 11 for sealing the opening 10 is detachably screwed into the opening 10.

Further, a sampling rod 12 is penetratingly provided in the longitudinal direction of the lid portion 11, and the tip of the sampling rod 12 immersed in the liquid 9 in the container body 8 is formed obliquely at a required angle. Is a collecting end 13 for collecting feces, and the other end is a bleeding portion 14 by projecting a required length from the lid 11. The collecting rod 12 is composed of a stick-shaped fiber bundle 15 formed by bundling a plurality of fibers.
A water resistant coating 16 is applied to the peripheral side surface of the (fiber bundle 15). As the material of the fibers, natural fibers such as cotton, wool and asbestos, and chemical fibers such as polyester fibers, acrylic fibers and nylon fibers are used.

In the figure, reference numeral 17 denotes an upper lid portion which is detachably screwed to the lid portion 11 and surrounds the exuding portion 14 by forming a closed space 18.

In FIG. 3, 19 is a micropipette.

According to the above construction, when the collecting rod 12 is detached from the container body 8 to collect feces, since the collecting rod 12 is made of the fiber bundle 15, the feces such as soft stool, diarrhea stool, watery stool, etc. Regardless of the physical properties, the feces are adsorbed in the fiber from the collecting end 13 of the collecting rod 12 and adhere to the peripheral side surface of the collecting rod 12 in the case of a paste.

Next, when the lid 11 is screwed into the container body 8 to seal the opening 10, the collection rod 12 integrated with the lid 11 and having the feces adsorbed and attached to the liquid 9 in the container body 8. Soak. Further, the upper lid 17 is fitted on the lid 11.

At this time, the container body 8 may be shaken to dissolve the feces in the liquid 9 and the liquid 9 may be carried as the fecal solution 9a (FIG. 3) to a place to be inspected or stored until the inspection. In advance, feces may be dissolved in the liquid 9 immediately before the inspection.

In the exuding portion 14 which is the closed space 18 by the upper lid portion 17, the fecal dissolving solution 9a slightly exudes due to the capillary action of the sampling rod 12 made of the fiber bundle 15, but the exuding portion 14 is surrounded. Since the enclosed space 18 is very small, the pressure in the enclosed space 18 becomes higher than the pressure in the container body 8 immediately, and the oozing of the fecal dissolution liquid 9a due to the capillary action of the sampling rod 12 hardly occurs. .

When carrying out the inspection, the upper lid portion 17 is removed.
Then, the exuding portion 14 is exposed to the outside air, and the pressure applied to the exuding portion 14 and the pressure in the container body 8 are balanced, so that the fecal dissolution liquid 9a exuded from the sampling end 13 of the sampling rod 12 is The sampling rod 12 formed of the bundle 15 oozes out like a water drop from the oozing section 14 due to the capillary phenomenon.

When the stool lysate 9a oozes out in the form of water droplets in the bleeding section 14, the stool lysate 9a is collected by a micropipette 19 or the like and used as a sample for detecting occult blood in the stool. . Alternatively, the feces solution 9a exuding in the form of water drops may be directly dropped and collected for use in the inspection.

Therefore, as described above, the stool collection rod 12
Since it is collected by adsorbing it from the collecting end 13 into the fiber, it can be collected regardless of the physical properties of feces such as loose stools, diarrhea stools, and watery stools. After that, only the feces dissolved in the liquid 9 exude from the exudation portion 14 by the capillarity of the sampling rod 12 made of the fiber bundle 15 as the feces dissolution liquid 9a. It is not necessary to provide a filtering device such as a filter for filtering the liquid 9 so that it can be used as a sample for detecting occult blood, and a simple structure can be obtained. Furthermore, since the sampling end 13 is configured obliquely at a required angle, a large area for adsorbing feces and a large area for the fecal dissolution solution 9a to permeate can be secured, and compared to the case where the sampling end 13 is configured horizontally. No more clogging.

Further, when the upper lid portion 17 is removed, the fecal dissolving solution 9a immediately oozes out from the bleeding portion 14. Therefore, a large number of samples are tested by arranging the container main bodies 8 from which the upper lid portion 17 is removed in order. It is also effective when
It is also suitable for test automation.

The present invention is not limited to the above-mentioned embodiments, and it goes without saying that various modifications can be made without departing from the gist of the present invention.

[0024]

As described above, according to the biological sample collecting container of the present invention, the following excellent effects can be obtained.

I) Since the feces are collected by adsorbing the feces from the collection end of the collection rod into the fibers, even if it is difficult to collect, such as loose stools, diarrhea stools, and watery stools, the physical properties of the stools will be improved. It can be collected regardless of.

II) Only the feces dissolved in the liquid is exuded from the exudation portion by the capillarity of the collection rod made of the fiber bundle as the fecal dissolution liquid, so that there is no need for a device for filtering the liquid in which the feces are dissolved. The sample container can have a simple structure.

III) According to the invention of claim 2,
Since the sampling end is configured obliquely at the required angle, it is possible to secure a large area for adsorbing feces and an area through which the fecal dissolution liquid permeates, and it is more clogged than when the sampling end is configured horizontally. Disappears.

IV) When the upper lid is removed, the fecal dissolution liquid immediately oozes out from the bleeding portion. Therefore, even when a large number of samples are tested by sequentially arranging the container bodies with the upper lid removed. Effective and suitable for test automation.

[Brief description of drawings]

FIG. 1 is a sectional view of an embodiment of the present invention.

FIG. 2 is a cross-sectional view of a position near a sampling end of a sampling rod.

FIG. 3 is a cross-sectional view showing a state in which a fecal dissolution solution exudes from an exudate portion due to a capillary phenomenon.

FIG. 4 is a cross-sectional view showing an example of a conventional fecal collection container.

[Explanation of symbols]

 8 Container Main Body 9 Liquid 10 Opening 11 Lid 12 Collection Rod 13 Collection End 14 Exudation 15 Fiber Bundle 17 Top Lid

Claims (2)

[Claims] 1. A container main body having an opening at an end and capable of containing a liquid, a lid portion capable of sealing the opening portion of the container main body, and a lid body which penetrates the lid portion densely and One end that can be immersed in a liquid is a collection end, and the other end side is a collection rod made of a fiber bundle that is a bleeding part by protruding a required length from the lid part,
A biological sample collection container, comprising: an upper lid portion configured to be fixed to the lid portion so as to surround and seal the exuding portion. 2. The biological sample collecting container according to claim 1, wherein the collecting end of the collecting rod is formed obliquely with a required angle.