JPH06183986A - Colloidal solution for treating intractable dermatitis and its production - Google Patents

Colloidal solution for treating intractable dermatitis and its production

Info

Publication number
JPH06183986A
JPH06183986A JP4361841A JP36184192A JPH06183986A JP H06183986 A JPH06183986 A JP H06183986A JP 4361841 A JP4361841 A JP 4361841A JP 36184192 A JP36184192 A JP 36184192A JP H06183986 A JPH06183986 A JP H06183986A
Authority
JP
Japan
Prior art keywords
give
treating
juice
colloidal solution
filtrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP4361841A
Other languages
Japanese (ja)
Inventor
Kunisaku Ueda
國作 植田
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to JP4361841A priority Critical patent/JPH06183986A/en
Publication of JPH06183986A publication Critical patent/JPH06183986A/en
Pending legal-status Critical Current

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  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicinal Preparation (AREA)

Abstract

PURPOSE:To obtain a colloidal solution for treating in tractable dermatitisdes, activating both immunological function and metabolic function, inducing neither side effect nor relapse by blending anhydrous ethanol with juice of cucurbita Pepo L. var. Kintoga an annual cucurbitaceous plant) under stirring, reacting and filtering with filter paper. CONSTITUTION:About 30vol.% anhydrous ethanol is mixed with about 70 vol.% juice of the Kintoga under stirring, reacted for >=72 hours and filtered through a filter paper. The filtrate is collected and optionally blended with perfume, glycerol, etc., to give the objective colloidal solution for treating in tractable dermatitides such as piles, chap cracks, etc. The filtrate is mixed with perfume to give a cosmetic for edema remover, beautiful skin, dandruff remover and itch remover or the filtrate is blended with an edible spice to give a preventive and therapeutic agent for deodorizing stomatitis, pyorrhea alveolaris and deodori zation of periodontitis or incorporated with an edible spice, sweetener and juice to give a healthy drink or further the remaining substance after the filtration is hermetically aged, decolored and can be used for treating ulcerative dermatitisdes, burn, etc.

Description

【発明の詳細な説明】Detailed Description of the Invention

【0001】[0001]

【産業上の利用分野】本発明は、金糸瓜の果実成分を、
無水エタノールを配合したコロイド液とし、塗布して、
免疫機能、代謝機能を賦活し、皮膜の保護、修復、再生
を、促進する、難治性皮膚炎治療用コロイド液、その製
造方法に関する。
BACKGROUND OF THE INVENTION The present invention relates to a fruit component of gold thread gourd,
Make a colloidal solution containing anhydrous ethanol, apply it,
The present invention relates to a colloidal solution for treating intractable dermatitis, which stimulates immune function and metabolic function, and promotes protection, repair and regeneration of a film, and a method for producing the same.

【0002】[0002]

【従来の技術】難治性皮膚炎は、自己免疫疾患、アレル
ギー疾患と称され、その原因については不明確で、その
治療法も確立されていない、除去食法、副腎皮質ステロ
イド軟膏塗布法が多用されている、しかし完治せず、副
作用が問題になっている。
BACKGROUND OF THE INVENTION Refractory dermatitis is called autoimmune disease or allergic disease, its cause is unclear, and its cure is not established. Elimination diet and corticosteroid ointment are frequently used. However, it is not cured completely and side effects are a problem.

【0003】[0003]

【発明が解決しようとする課題】従来の単離した薬物に
は、効果と副作用が共存するものが多い、それは単離し
たものでは、微妙な生化学的複合作用に適応性を欠く為
と考えられる、その条件を満たし得るものとして、植物
成分を自然のまま利用することが最適であると考えられ
る、副作用の心配のない食用植物の中から、特性のある
金糸瓜の選択に5年余を要した、金糸瓜の多様な著効特
性を次々に発見、その成分をコロイド液にし、効果及び
副作用の試用に6年余をかけ、本発明を完成した。金糸
瓜は、通称名を、日本ではそうめん南瓜、アメリカでは
スパゲッテイースクュワッシ(spaghetti−s
quash)、学名をカクゥァビターマクシィマ(cu
ccurbita−maxima)と称し、専ら煮る、
焼く、などして食用にのみに利用されているが、その成
分が難治性皮膚炎に著効あることは知られていない。
Many of the conventional isolated drugs coexist with effects and side effects. It is considered that the isolated drugs lack adaptability to subtle biochemical complex action. It is said that it is best to use the plant components as they are, as the ones that can satisfy the conditions, and it takes more than 5 years to select the characteristic gold thread gourd from the edible plants that do not cause side effects. The required various properties of gold spinach were discovered one after another, and the components were made into a colloidal solution, and it took more than 6 years to test the effects and side effects, and the present invention was completed. Gold thread gourd is commonly known as somen squash in Japan and spaghetti swash in the United States.
quash), and the scientific name is cuquabiter maxima (cu
ccurbita-maxima) and cooks exclusively,
It is used only for food such as baking, but its ingredients are not known to be effective against intractable dermatitis.

【0004】[0004]

【課題を解決する手段】本発明の金糸瓜の成分中には、
70℃以上の熱で失活するものが含まれてるので、常温
での製造法が必須条件である、常温下での防腐、消毒、
を兼ねるものとして、無水エタノールを溶媒に採択す
る。金糸瓜の自然成分の均一性を考え、金糸瓜の自然成
分を分散質、錦糸瓜の水分と無水エタノールの混合液を
分散媒、から成るコロイド液である。
[Means for Solving the Problems] Among the components of the gold thread gourd of the present invention are:
Since it contains substances that are inactivated by heat of 70 ° C or higher, preserving and sterilizing at room temperature are essential conditions for manufacturing at room temperature.
Absolute ethanol is adopted as a solvent for the double use. Considering the homogeneity of the natural components of gold melon, it is a colloidal liquid consisting of the dispersoid of the natural components of gold melon and the dispersion medium of the mixed liquid of water and absolute ethanol of melon.

【具体例1】体積比約30%の無水タノール中に、金糸
瓜の果汁を体積比約70%を混合撹拌して、72時間以
上反応させる。
Specific Example 1 About 70% by volume of gold ginger melon juice is mixed and stirred in about 30% by volume of anhydrous tanol, and the mixture is reacted for 72 hours or more.

【具体例2】具体例(1)の混合液を濾過紙で濾過す
る、錦糸瓜の成分を分散質、錦糸瓜の水分と無水エタノ
ールの混合液を分散媒、から成るコロイド液ができる、
難治性皮膚炎治療用コロイド液である。
[Specific Example 2] The mixed solution of Specific Example (1) is filtered through a filter paper to form a colloidal solution containing a dispersoid of the ingredients of Kinshiku melon and a dispersion medium of a mixed solution of water of Kinshiku melon and absolute ethanol.
It is a colloidal solution for treating intractable dermatitis.

【具体例3】請求項(3)には、具体例(2)に香料1
%、グリセリン10%を添加。請求項(4)には、具体
例(2)に香料1%を添加。請求項(5)には、具体例
(2)に食用香料1%を添加。請求項(6)には、具体
例(2)に食用香料1%,甘味料0〜5%、果汁85%
〜95%を添加。請求項(7)は、濾過後、濾過紙に付
着している残滓を採りまとめて密封し、2カ月以上熟成
させる、熟成の目安は、白色になり、香りも変わる。
SPECIFIC EXAMPLE 3 Claim (3) defines the specific example (2) as perfume 1
%, Glycerin 10% added. In claim (4), 1% of fragrance is added to the specific example (2). In claim (5), 1% of food flavor is added to the specific example (2). Claim (6) provides the specific example (2) with 1% edible flavor, 0-5% sweetener, and 85% fruit juice.
~ 95% added. According to claim (7), after filtering, the residue attached to the filter paper is collected, sealed, and aged for 2 months or more. The standard of aging becomes white and the scent changes.

【0005】[0005]

【作用】免疫機構活性の機序は、侵入して来たウイル
ス、その他の異物を、マクロファージが貧食して、その
細胞膜に抗原提示をし、インターロイキン−1(IL−
1)を分泌して、インデューサー/ヘルパーT4リンパ
細胞を賦活する。ヘルパーT4はインターロイキン−2
(IL−2)を分泌して、細胞障害性/サプレッサーT
8リンパ細胞及びBリンパ細胞(液性免疫)を賦活す
る。同時にヘルパーT4はγ−インターフェロンをも分
泌して、マクロファージを賦活する。この様に免疫機構
の複合作用(フィードバック)により免疫機能は維持さ
れている、最近のの理論である。皮膚炎の治療には、免
疫機能と代謝機能が併行的に活性化することが必須条件
であると考えられる、単離した薬物では、その条件を満
たし得ない。このコロイド液には、金糸瓜の成分が分散
質として、代謝に必要な物質(アミノ酸、リボゾーム、
Mg+2,微量物質)が総て含まれていて、夫々の固体
が必要物質を適量、選択的に摂取できるので、無理なく
代謝が機能する。このコロイド液は、無水エタノールに
より、常温での腐廃変質を防ぎ、皮膚を消毒する。コロ
イド状なので、自然成分が、ブラウン運動により、均一
に分散していて、皮膜細胞は、必要成分の選択、摂取、
が容易である。皮膚の環境は、阻害物質の種類が多く、
個体差もあるので免疫、代謝にも多様性が求められる、
このコロイド液は、その要求を満たし得るものとして稀
有のものである。金糸瓜は食用植物であり、無水エタノ
ールは、厚生省の化粧品原料基準成分規格S0506の
認定品であり、その他添加物も厚生省原料基準成分規格
に遵じて添加するので、副作用がなく安全である。
[Action] The mechanism of immune system activity is that macrophages phagocytose the invading virus and other foreign substances, presenting antigens to their cell membranes, and interleukin-1 (IL-
1) is secreted to activate inducer / helper T4 lymphocytes. Helper T4 is interleukin-2
Secreting (IL-2) and cytotoxic / suppressor T
Activates 8 lymphocytes and B lymphocytes (humoral immunity). At the same time, helper T4 also secretes γ-interferon and activates macrophages. Thus, it is a recent theory that the immune function is maintained by the combined action (feedback) of the immune mechanism. For the treatment of dermatitis, it is considered that the concurrent activation of immune function and metabolic function is an essential condition, and the isolated drug cannot satisfy the condition. In this colloidal solution, the components of gold thread gourd are used as dispersoids and substances necessary for metabolism (amino acids, ribosomes,
(Mg +2 , trace substances) are all contained, and each solid can selectively ingest the appropriate amount of the required substance, so that the metabolism functions naturally. This colloidal liquid prevents the deterioration of the skin at room temperature by using anhydrous ethanol and disinfects the skin. Since it is colloidal, natural components are evenly dispersed by Brownian movement, and the membrane cells select necessary components, ingest,
Is easy. There are many types of inhibitors in the skin environment,
Since there are individual differences, diversity is required for immunity and metabolism.
This colloidal liquid is rare as one that can meet the requirements. Gold thread gourd is an edible plant, absolute ethanol is an approved product of the cosmetic raw material standard component standard S0506 of the Ministry of Health and Welfare, and other additives are added in compliance with the Ministry of Health and Welfare standard component standard, so there is no side effect and it is safe.

【0006】[0006]

【実施例1】具体例2の塗布により、アトピー性皮膚
炎、天庖瘡、帯状庖疹、に著効あり。
[Example 1] The application of Example 2 is very effective against atopic dermatitis, pimples, and herpes zoster.

【実施例2】具体例(3)の塗布により、痔疾、ひび割
れ、に有効。
[Example 2] The application of the specific example (3) is effective against hemorrhoids and cracks.

【実施例3】具体例(4)の塗布により、浮腫、凝り、
痙攣、痒み、ふけ、の消去用。
Example 3 By applying the specific example (4), edema, stiffness,
For elimination of convulsions, itching and dandruff.

【実施例4】具体例(5)の塗布、漱により、消臭、口
軟炎、歯槽膿漏、の予防、治療用。
[Example 4] For the prevention and treatment of deodorization, mouth sores, and alveolar pyorrhea by applying and straining the specific example (5).

【実施例5】具体例(6)を飲むことにより、健康飲料
になる。
[Example 5] A healthy beverage can be obtained by drinking the specific example (6).

【実施例6】具体例(7)の塗布により、潰瘍性皮膚
炎、火傷、の治療用。
Example 6 For the treatment of ulcerative dermatitis and burns by applying the specific example (7).

【0007】[0007]

【発明の効果】本発明は、以上説明したように、金糸瓜
の自然成分を分散質、錦糸瓜の水分と無水エタノールの
混合液を分散媒、から成るのコロイド液なので、以下に
記載するような効果がある。無水エタノール中に金糸瓜
を搾汁するには、空気との接触を少なくし、常温下での
変質を防ぎ、錦糸瓜の不純物及び既成タンパク質を、反
応沈澱させる必要がある。常温という条件は、自然成分
の生化学的活性を維持する為の必須条件である、酵素活
性は、35〜40℃が最適温度範囲であり、特に70〜
80℃で失活するので、常温での防腐、消毒、の条件
を、無水エタノールにより満たしている。このコロイド
液は、マクロファージの活性化と感染防御効果が動物実
験で確認されている、マクロファージは免疫機能の中心
的な役割をしているものなので、そのデーターは、確認
されている多様な著効の裏付けとして貴重である。最
近、皮膚が胸腺、リンパ腺、脾臓、と並ぶ免疫器官であ
ることが分かった、故に、皮膚のランゲルハンス、ケラ
チノサイト、メラノサイト、もマクロファージと共に賦
活するものと考えられる、自然の免疫、代謝、の機序に
沿うこのコロイド液は、副作用のない健康飲料、化粧
品、薬品、として提供できる。 このコロイド液の動物実験データー マクロファージ 1%で活性化 感染防御 0.1ml/マウス以上で有効
Industrial Applicability As described above, the present invention is a colloidal liquid comprising a dispersoid of the natural component of gold melon and a dispersion medium of a mixed solution of water and water-soluble ethanol of quince melon. It has a great effect. In order to squeeze gold thread gourd in anhydrous ethanol, it is necessary to reduce contact with air, prevent alteration at room temperature, and cause reaction precipitation of the impurities and ready-made protein in kinshi gourd. The condition of normal temperature is an essential condition for maintaining the biochemical activity of natural ingredients. The enzyme activity has an optimum temperature range of 35 to 40 ° C., especially 70 to 40 ° C.
Since it deactivates at 80 ° C, the conditions of antiseptic and sterilization at room temperature are satisfied with anhydrous ethanol. In this colloidal solution, activation of macrophages and protection against infection have been confirmed in animal experiments.Since macrophages play a central role in immune function, the data show that they have various confirmed effects. It is valuable as a proof of. Recently, the skin was found to be an immune system along with the thymus, lymph gland, and spleen. Therefore, the skin's Langerhans, keratinocytes, and melanocytes are also considered to be the mechanisms of natural immunity and metabolism that are thought to activate together with macrophages. This colloidal solution according to the order can be provided as a health drink, cosmetics, or medicine without side effects. Animal experiment data of this colloidal liquid Activated by macrophage 1% Protected against infection Effective at 0.1 ml / mouse or more

───────────────────────────────────────────────────── フロントページの続き (51)Int.Cl.5 識別記号 庁内整理番号 FI 技術表示箇所 A61K 7/48 9051−4C 9/107 S 7329−4C ─────────────────────────────────────────────────── ─── Continuation of the front page (51) Int.Cl. 5 Identification code Internal reference number FI Technical display location A61K 7/48 9051-4C 9/107 S 7329-4C

Claims (7)

【特許請求の範囲】[Claims] 【請求項1】 金糸瓜の果実成分を分散質、果実の水分
と無水エタノールの混合液を分散媒、から成る、難治性
皮膚炎症治療用コロイド液。
1. A colloidal liquid for the treatment of intractable skin inflammation, which comprises a dispersoid of a fruit component of gold thread gourd and a dispersion medium of a mixture of fruit water and absolute ethanol.
【請求項2】 体積比約30%の無水エタノール中に、
金糸瓜の果汁を体積比約70%混入撹拌して、72時間
以上反応させ、濾過紙で濾過する、コロイト液の製造方
法。
2. In absolute ethanol of about 30% by volume,
A method for producing a coroit solution, which comprises mixing 70% by volume of gold thread gourd juice, stirring the mixture, reacting for 72 hours or more, and filtering with a filter paper.
【請求項3】 請求項(1)に香料、グリセリン、を加
えて痔疾、ひび割れ、の治療用コロイド液。
3. A colloidal solution for treating hemorrhoids and cracks, which is obtained by adding a fragrance and glycerin to claim 1.
【請求項4】 請求項(1)に香料を加えて、浮腫と
り、美肌、ふけとり、消痒、の化粧料。
4. A cosmetic for edema, beautiful skin, dandruff, antipruritic, which is obtained by adding a fragrance to claim (1).
【請求項5】 請求項(1)に食用香料を加えて、口軟
炎、歯槽膿漏、歯周病消臭、の予防、治療用コロイド
液。
5. A colloidal liquid for preventing and treating mouth sores, alveolar pyorrhea, and deodorization of periodontal disease, which is obtained by adding an edible flavor to claim (1).
【請求項6】 請求項(1)に食用香料、甘昧料、果汁
を調合して、健康飲料にする。
6. A healthy drink is prepared by mixing the edible flavor, sweetener and fruit juice according to claim 1.
【請求項7】 請求項(1)の濾過による残留物質を、
密閉塾生させると、脱色して白色の軟膏になる、潰瘍性
皮膚炎、火傷、の治療用軟膏。
7. The residual substance obtained by filtration according to claim 1,
An ointment for the treatment of ulcerative dermatitis and burns, which is a white ointment that is decolorized when sealed.
JP4361841A 1992-12-22 1992-12-22 Colloidal solution for treating intractable dermatitis and its production Pending JPH06183986A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP4361841A JPH06183986A (en) 1992-12-22 1992-12-22 Colloidal solution for treating intractable dermatitis and its production

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4361841A JPH06183986A (en) 1992-12-22 1992-12-22 Colloidal solution for treating intractable dermatitis and its production

Publications (1)

Publication Number Publication Date
JPH06183986A true JPH06183986A (en) 1994-07-05

Family

ID=18475037

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4361841A Pending JPH06183986A (en) 1992-12-22 1992-12-22 Colloidal solution for treating intractable dermatitis and its production

Country Status (1)

Country Link
JP (1) JPH06183986A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07309713A (en) * 1994-05-20 1995-11-28 Narisu Keshohin:Kk Skin composition
JP2014237608A (en) * 2013-06-07 2014-12-18 株式会社日本食品薬化 Estrogenic agent, melanogenesis inhibitory agent, external preparation for skin, and food and drink for cosmetic use
JP6122198B1 (en) * 2016-09-16 2017-04-26 カゴメ株式会社 Beverage texture imparting method, beverage and production method thereof
JP2018042547A (en) * 2017-03-24 2018-03-22 カゴメ株式会社 Texture adding method of beverage, beverage and manufacturing method therefor

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07309713A (en) * 1994-05-20 1995-11-28 Narisu Keshohin:Kk Skin composition
JP2014237608A (en) * 2013-06-07 2014-12-18 株式会社日本食品薬化 Estrogenic agent, melanogenesis inhibitory agent, external preparation for skin, and food and drink for cosmetic use
JP6122198B1 (en) * 2016-09-16 2017-04-26 カゴメ株式会社 Beverage texture imparting method, beverage and production method thereof
JP2018042547A (en) * 2017-03-24 2018-03-22 カゴメ株式会社 Texture adding method of beverage, beverage and manufacturing method therefor

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