JPH06145034A - Ultraviolet ray preventing cosmetic - Google Patents
Ultraviolet ray preventing cosmeticInfo
- Publication number
- JPH06145034A JPH06145034A JP30075492A JP30075492A JPH06145034A JP H06145034 A JPH06145034 A JP H06145034A JP 30075492 A JP30075492 A JP 30075492A JP 30075492 A JP30075492 A JP 30075492A JP H06145034 A JPH06145034 A JP H06145034A
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- cosmetic
- rosmarinic acid
- ultraviolet
- effect
- skin
- Prior art date
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- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cosmetics (AREA)
Abstract
Description
【０００１】[0001]
【産業上の利用分野】本発明は化粧料に関し、詳しく
は、紫外線防止効果に優れた化粧料を提供するものであ
る。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to cosmetics, and more specifically, to a cosmetic excellent in the effect of preventing ultraviolet rays.
【０００２】[0002]
【従来の技術】従来、日焼けを防止するために、紫外線
吸収剤、紫外線散乱剤等を配合した化粧料が使用されて
いる。このような化粧料を皮膚に塗布すると、皮膚表面
で紫外線を吸収、散乱させて日焼けを防止することがで
きる。2. Description of the Related Art Conventionally, cosmetics containing UV absorbers, UV scatterers, etc. have been used to prevent sunburn. When such a cosmetic is applied to the skin, ultraviolet rays can be absorbed and scattered on the skin surface to prevent sunburn.
【０００３】また、ジヒドロキシアセトン（ＤＨＡ）
と、染料の一種であるラウソン（Lawson）を併用する
と、皮膚角層中で紫外線や短波長領域の可視光線を吸収
させる効果を有することが報告されており（フレグラン
ス ジャーナル No. 43 (1980)）、特に日光過敏症患者
に対する紫外線防止法として有効性を示す報告が多数知
られている（例えば、International Journal of Derma
tology, 11, No.2, (1972)） 。Further, dihydroxyacetone (DHA)
It has been reported that when used together with Lawson, which is a type of dye, it has the effect of absorbing ultraviolet rays and visible light in the short wavelength region in the stratum corneum of the skin (Fragrance Journal No. 43 (1980)). , And there are many reports that show its effectiveness as a UV protection method, especially for patients with photosensitivity (for example, International Journal of Derma
tology, 11, No.2, (1972)).
【０００４】尚、ロズマリン酸を含有する化粧料が、抗
酸化作用、美肌効果、美白効果、養毛効果を有すること
が知られている（特開昭６３−１６２６１１号公報）
が、紫外線防止効果を有することは知られていない。It is known that cosmetics containing rosmarinic acid have an antioxidant effect, a skin beautifying effect, a whitening effect, and a hair nourishing effect (JP-A-63-162611).
However, it is not known to have an ultraviolet ray-preventing effect.
【０００５】[0005]
【発明が解決しようとする課題】上述の紫外線吸収剤や
紫外線散乱剤を使用した従来の化粧料は、皮膚に塗布し
た直後は紫外線防止効果を有するが、衣類等による摩擦
や洗滌で脱離しやすく、そのために紫外線防止効果の持
続性がよくないという問題点がある。The conventional cosmetics using the above-mentioned ultraviolet absorber or ultraviolet scatterer have an ultraviolet ray-preventing effect immediately after being applied to the skin, but are easily removed by rubbing or washing with clothes or the like. Therefore, there is a problem that the durability of the ultraviolet ray protection effect is not good.
【０００６】また、ＤＨＡとラウソンを併用した化粧料
は、ある程度のサンスクリーン効果を持続して発揮する
ことはできるが、同時にタンニング作用を有し、皮膚を
美容上好ましくない色調に変化させたり、光線吸収効果
が小さいなどの問題点が残されている。[0006] Further, the cosmetics in which DHA and lausone are used in combination can exert a certain sunscreen effect continuously, but at the same time, they have a tanning effect and change the skin to a color tone which is not cosmetically favorable, There are problems such as a small light absorption effect.
【０００７】本発明は、このような観点からなされたも
のであり、上記問題点を克服するために、耐摩擦性、耐
洗滌性に優れ、持続性の良い紫外線防止効果を有すると
ともに、皮膚を好ましい肌色に着色させることができる
化粧料を提供することを課題とする。The present invention has been made from such a point of view, and in order to overcome the above-mentioned problems, it has excellent abrasion resistance and washing resistance, has a long-lasting effect of preventing ultraviolet rays, and protects the skin. An object of the present invention is to provide a cosmetic that can be colored in a desirable skin color.
【０００８】[0008]
【課題を解決するための手段】本発明者は、上記課題を
解決するために鋭意研究を行った結果、ロズマリン酸及
びその塩が紫外線吸収作用を有し、しかも皮膚角層中の
特定のアミノ酸と反応して紫外線特にＵＶ−Ｂ領域及び
短波長可視光を吸収する層を形成することを見出し、本
発明に至った。Means for Solving the Problems As a result of intensive research to solve the above problems, the present inventor has found that rosmarinic acid and its salts have an ultraviolet-absorbing action and, in addition, specific amino acids in the stratum corneum of the skin. The present invention was found to form a layer that reacts with to absorb ultraviolet rays, especially in the UV-B region and short-wavelength visible light.
【０００９】すなわち本発明は、ロズマリン酸又は／及
びその塩を、化粧料全量に対し０．０１〜１０重量％含
有する紫外線防止化粧料である。また本発明は、ロズマ
リン酸とともに、さらにリジン又は／及びアルギニンか
ら選ばれるアミノ酸を化粧料全量に対し０．０１〜１０
重量％含有する紫外線防止化粧料を提供する。That is, the present invention is an ultraviolet-preventing cosmetic containing rosmarinic acid or / and a salt thereof in an amount of 0.01 to 10% by weight based on the total amount of the cosmetic. Further, the present invention, together with rosmarinic acid, further contains an amino acid selected from lysine and / or arginine in an amount of 0.01 to 10 relative to the total amount of the cosmetic.
Provided is a UV-preventing cosmetic material which is contained by weight.
【００１０】以下、本発明を詳細に説明する。 ＜１＞本発明に用いるロズマリン酸及びその塩 ロズマリン酸は、下記化１で表される物質であり、主と
して、マンネンロウ、アオジソ、チリメンジソ、カワミ
ドリ、延命草等のシソ科植物に含まれていることが知ら
れており、これらから抽出することができる。また、化
学合成することも可能である。The present invention will be described in detail below. <1> Rosmarinic acid and a salt thereof used in the present invention is a substance represented by the following chemical formula 1, and is mainly contained in Lamiaceae plants such as mannen wax, aojiso, chili menjiso, kawamidori, and life-prolonging grass. Are known and can be extracted from these. It is also possible to chemically synthesize.
【００１１】[0011]
【化１】 [Chemical 1]
【００１２】以下に、ロズマリン酸の製法の一例とし
て、マンネンロウから抽出する例を示す。マンネンロウ
の乾燥葉を粗粉砕し、水と任意の割合で混じり合う有機
溶媒を用いて抽出操作を行う。得られる抽出物から有機
溶媒を留去した後、適量の水を加え、クロロホルム、ク
ロルメチレン等のハロゲン化溶剤、エチルエーテル等の
比較的極性の低い溶媒を用いて水層を洗滌する。As an example of the method for producing rosmarinic acid, an example of extracting from mannose wax will be shown below. Dry leaves of mannen wax are roughly crushed, and an extraction operation is performed using an organic solvent that is mixed with water at an arbitrary ratio. After distilling off the organic solvent from the obtained extract, an appropriate amount of water is added, and the aqueous layer is washed with a halogenated solvent such as chloroform and chloromethylene, and a solvent having a relatively low polarity such as ethyl ether.
【００１３】次に、洗滌した水層を無機又は有機酸を用
いてｐＨ３付近に調製する。これを酢酸エチル、ブタノ
ール等の比較的極性の高い有機溶媒を用いて抽出操作を
行う。このようにして、ロズマリン酸を３５〜５０％含
む抽出物が得られる。さらに、これを樹脂カラムを用い
て水−メタノール系の溶媒を使用して精製すれば、純度
９５〜９９％のロズマリン酸が得られる。Next, the washed aqueous layer is adjusted to a pH of about 3 using an inorganic or organic acid. This is extracted with an organic solvent having a relatively high polarity such as ethyl acetate or butanol. In this way, an extract containing 35-50% rosmarinic acid is obtained. Further, if this is purified using a resin column and a water-methanol solvent, rosmarinic acid having a purity of 95 to 99% can be obtained.
【００１４】本発明においては、ロズマリン酸の他、そ
の塩も使用することができる。塩形成成分としては、例
えば、水酸化ナトリウム、水酸化マグネシウム等の無機
塩類、ヒスチジン、モノエタノールアミン、トリエタノ
ールアミン等の有機塩類が挙げられる。これらの塩は、
予め調製しておいてもよいし、化粧料中に塩形成成分と
ロズマリン酸とを添加して、処方中で反応させて塩を形
成させてもよい。その他、ロズマリン酸、その塩及びこ
れらの製法については、特開昭６３−１６２６１１号公
報に詳しい。In the present invention, in addition to rosmarinic acid, salts thereof can be used. Examples of the salt-forming component include inorganic salts such as sodium hydroxide and magnesium hydroxide, and organic salts such as histidine, monoethanolamine and triethanolamine. These salts are
The salt may be prepared in advance, or the salt-forming component and rosmarinic acid may be added to the cosmetic and reacted in the formulation to form a salt. Other details of rosmarinic acid, salts thereof, and methods for producing them are described in JP-A-63-162611.
【００１５】本発明の化粧料は、上記ロズマリン酸ある
いはその塩を、単独あるいは任意の混合物として、化粧
料全量に対し０．０１〜１０重量％、好ましくは０．５
〜２重量％含有する。含有量がこれよりも少ないと、紫
外線防止効果が期待できず、また、含有量がこれより多
くても、効果が頭打ちになるので、上記範囲が好まし
い。The cosmetic of the present invention contains the above-mentioned rosmarinic acid or a salt thereof, alone or in an arbitrary mixture, in an amount of 0.01 to 10% by weight, preferably 0.5, based on the total amount of the cosmetic.
~ 2 wt% contained. When the content is less than this range, the effect of preventing ultraviolet rays cannot be expected, and when the content is more than this range, the effect reaches the ceiling, so the above range is preferable.
【００１６】また本発明には、精製したロズマリン酸以
外に、ロズマリン酸を含有する上記シソ科植物の抽出物
を、ロズマリン酸の量が上記範囲内になるようにして使
用してもよい。In addition to the purified rosmarinic acid, an extract of the Lamiaceae plant containing rosmarinic acid may be used in the present invention so that the amount of rosmarinic acid falls within the above range.
【００１７】＜２＞リジン、アルギニン ロズマリン酸は、それ自体で紫外線吸収作用を有する
が、皮膚角層に吸収されると、皮膚中のリジン、アルギ
ニンと反応することにより紫外線防止作用を有する層を
形成する。その結果、持続性のよい紫外線防止効果を発
揮することができる。<2> Lysine and Arginine Rosmarinic acid has an ultraviolet absorbing effect by itself, but when absorbed by the stratum corneum of the skin, it reacts with lysine and arginine in the skin to form a layer having an ultraviolet preventing effect. Form. As a result, it is possible to exert a long-lasting ultraviolet ray preventing effect.
【００１８】通常、皮膚角層中にはリジンやアルギニン
が存在しているため、ロズマリン酸のみを化粧料に配合
しても紫外線防止効果を発揮し得るが、リジン及び／又
はアルギニンを併用すると、より確実に効果が得られ
る。また、ロズマリン酸を高濃度で化粧料中に溶解させ
ると、一旦は溶解し、保存中に析出するが、リジン及び
／又はアルギニンを併用すると析出を防ぐことができ
る。Usually, since lysine and arginine are present in the stratum corneum of the skin, even if only rosmarinic acid is added to a cosmetic composition, it is possible to exert an ultraviolet ray-preventing effect, but when lysine and / or arginine are used in combination, The effect can be obtained more reliably. In addition, when rosmarinic acid is dissolved in cosmetics at a high concentration, it is once dissolved and precipitated during storage, but when lysine and / or arginine is used together, precipitation can be prevented.
【００１９】上記アミノ酸の含有量は、化粧料全量に対
し０．０１〜１０重量％、好ましくは０．５〜５重量％
が望ましく、単独でも混合物としても使用できる。これ
らのアミノ酸を併用する場合は、ロズマリン酸とともに
予め化粧料に配合することもできるが、ロズマリン酸と
反応して着色するので、ロズマリン酸が低濃度である場
合は、ロズマリン酸を含む化粧料と前記アミノ酸を含む
化粧料を、使用時に手の平等で混合して用いるのが好ま
しい。また、これらの化粧料のうち一方を塗布し、続い
て他方の化粧料を塗布してもよい。一方、高濃度の場合
は、ロズマリン酸の析出を防止するために、予めリジン
等と共に化粧料に配合しておいてもよい。The content of the above amino acid is 0.01 to 10% by weight, preferably 0.5 to 5% by weight, based on the total amount of the cosmetic.
However, they can be used alone or as a mixture. When these amino acids are used in combination, they can be mixed in advance with the rosmarinic acid in the cosmetics, but since they react with the rosmarinic acid to color, when the rosmarinic acid is at a low concentration, a cosmetic containing rosmarinic acid is used. It is preferable to mix the cosmetics containing the amino acid with the palm of the hand before use. Further, one of these cosmetics may be applied, and subsequently the other cosmetic may be applied. On the other hand, in the case of a high concentration, in order to prevent the precipitation of rosmarinic acid, it may be preliminarily blended in the cosmetic together with lysine and the like.
【００２０】＜３＞その他の成分 本発明の化粧料には、上記成分の他、通常の化粧料に用
いられる各種の化粧品用基剤及び添加物、例えば無機顔
料、有機顔料、無機粉体、有機粉体、炭化水素類、シリ
コーン類、エステル類、トリグリセリド類、ラノリン
類、ワックス類、ロウ類、動植物油、界面活性剤、多価
アルコール類などの基剤や糖類、ビタミンＡ、ビタミン
Ｂ群、ビタミンＥなどのビタミン類、アミノ酸類、グリ
チルリチン若しくはグリチルレチン酸あるいはこれらの
誘導体などの抗炎症剤、酸化防止剤、防腐剤、香料、増
粘剤、収斂剤、細胞賦活剤、美白剤、肌荒れ改善剤、さ
らに従来使用されている紫外線吸収剤、紫外線散乱剤等
の添加物を配合することができる。ただし、リジン等を
併用する場合は、脂肪酸は添加しない方がよい。<3> Other Components In the cosmetic of the present invention, in addition to the above components, various cosmetic bases and additives used in ordinary cosmetics, such as inorganic pigments, organic pigments, inorganic powders, Organic powder, hydrocarbons, silicones, esters, triglycerides, lanolins, waxes, waxes, bases such as animal and vegetable oils, surfactants, polyhydric alcohols, sugars, vitamin A, vitamin B group , Vitamins such as vitamin E, amino acids, anti-inflammatory agents such as glycyrrhizin or glycyrrhetinic acid or derivatives thereof, antioxidants, preservatives, fragrances, thickeners, astringents, cell activating agents, whitening agents, skin roughening improvement Agents, and additives such as UV absorbers and UV scatterers which have been conventionally used can be added. However, when lysine or the like is used in combination, it is better not to add fatty acid.
【００２１】また、本発明の化粧料の剤型は特に制限さ
れず、通常の化粧料の製法に従って製造することができ
る。Further, the dosage form of the cosmetic of the present invention is not particularly limited, and the cosmetic can be manufactured according to a usual cosmetic manufacturing method.
【００２２】[0022]
【作用】図１に、ロズマリン酸、及びリジンあるいはア
ルギニンと反応させたロズマリン酸の吸収スペクトルを
示す。対照として、従来使用されているラウソンとリジ
ンとの混合物の吸収スペクトルを示す。FIG. 1 shows the absorption spectra of rosmarinic acid and rosmarinic acid reacted with lysine or arginine. As a control, the absorption spectrum of a conventionally used mixture of lauson and lysine is shown.
【００２３】ラウソンは、紫外線吸収作用をある程度有
するが、極大値が４５０ｎｍ付近であり、これが化粧料
に使用した場合に皮膚がオレンジ色に着色される原因と
なっている。[0023] Lawson has an ultraviolet absorbing effect to some extent, but its maximum value is around 450 nm, which causes the skin to be colored orange when used in cosmetics.
【００２４】これに対し、ロズマリン酸はＵＶ−Ｂ領域
を中心として可視光短波長領域を含めて紫外線吸収作用
を示し、ラウソンのように美容的に好ましくない皮膚色
に変化させることはない。また、ロズマリン酸をリジン
あるいはアルギニンと反応させた場合、吸収スペクトル
は若干変化し、可視光短波長領域の吸光度が増大する
が、ＵＶ−Ｂ領域を中心とした紫外線吸収作用は維持さ
れる。これにより、紫外線防止効果を有するとともに、
皮膚を褐色に着色することができる。On the other hand, rosmarinic acid exhibits an ultraviolet absorbing action centering on the UV-B region including the visible light short wavelength region, and does not change to a cosmetically unfavorable skin color like Lawson. When rosmarinic acid is reacted with lysine or arginine, the absorption spectrum changes slightly and the absorbance in the short wavelength region of visible light increases, but the ultraviolet absorbing action centered on the UV-B region is maintained. This has the effect of preventing ultraviolet rays,
The skin can be colored brown.
【００２５】後記実施例に示すように、リジン等を併用
するとロズマリン酸による紫外線防止効果は向上するの
で、これらが反応して皮膚角層中に紫外線防止層を形成
すると推定される。As will be shown in Examples below, the combined use of lysine and the like enhances the effect of rosmarinic acid to prevent ultraviolet rays, and it is presumed that these react to form an ultraviolet ray preventive layer in the stratum corneum of the skin.
【００２６】[0026]
【実施例】以下に、本発明の実施例を説明する。EXAMPLES Examples of the present invention will be described below.
【００２７】[0027]
【実施例１〜５】本発明の紫外線防止化粧料として、乳
液における実施例を説明する。 （製法）表１Ａ、Ｂの成分を各々撹拌しながら溶解し、
Ｂの成分にＡの成分を加え、予備乳化を行い、ホモミキ
サーで均一に乳化した。乳化後撹拌しながら５０℃まで
冷却した。これに、５０℃に加熱保温したＣの成分を撹
拌しながら加え、３０℃になるまで撹拌を続けながら冷
却した。同様にしてロズマリン酸を含まない比較例の乳
液を製造した。Examples 1 to 5 Examples of emulsions of the present invention will be described as emulsions for preventing ultraviolet rays. (Production method) Dissolve the components of Tables 1A and 1B with stirring,
The component A was added to the component B to carry out preliminary emulsification and homogenize with a homomixer. After emulsification, the mixture was cooled to 50 ° C with stirring. To this, the component C heated and kept at 50 ° C. was added with stirring, and the mixture was cooled with stirring until it reached 30 ° C. In the same manner, a comparative emulsion containing no rosmarinic acid was produced.
【００２８】[0028]
【表１】 [Table 1]
【００２９】（評価）上記の各実施例及び比較例で得ら
れた乳液を２種類組み合わせて使用し、各々について紫
外線防止効果を評価した。初めにリジンを含む比較例２
の乳液を塗布した後に、ロズマリン酸を含む実施例の乳
液を塗布した。対照として、実施例３、及び比較例１、
２の乳液を単独で使用した。(Evaluation) Two kinds of emulsions obtained in each of the above Examples and Comparative Examples were used in combination, and the ultraviolet ray preventing effect was evaluated for each. Comparative Example 2 initially containing lysine
After applying the emulsion of Example 1, the emulsion of Example containing rosmarinic acid was applied. As a control, Example 3 and Comparative Example 1,
Two emulsions were used alone.
【００３０】紫外線防止効果の評価は、ＳＰＦ（Sun pr
otection factor：日焼け止め指数）値を測定すること
により行った。このＳＰＦ測定は、以下に示すモルモッ
ト皮膚表皮を用いた代替法により行った。尚、本方法は
ＦＤＡ法（ヒトの皮膚に日焼け止め剤を塗布して紫外線
を照射し、日焼け止め剤を使用しない場合に対して皮膚
に同等の炎症を起こさせる照射エネルギー量（時間）の
比で表す方法）と非常に高い相関を示す方法である。The evaluation of the UV protection effect is carried out by SPF (Sun pr
otection factor: sunscreen index) value was measured. This SPF measurement was performed by an alternative method using the guinea pig skin epidermis shown below. This method is based on the FDA method (the ratio of the amount of irradiation energy (time) that causes the skin to be inflamed to the same level as when the sunscreen was not used by applying a sunscreen to human skin and irradiating it with ultraviolet rays. This is a method showing a very high correlation with the method shown in.
【００３１】ヘアレスモルモットの皮膚組織を剥離し、
真皮下の脂肪、筋肉をピンセットで除去し、ディスパー
ゼ（合同酒精（株）製タンパク分解酵素：バチルス・ポ
リミキサ由来）を１０００ＰＵ／ｍｌを含むリン酸緩衝
生理食塩水に浸漬し、３７℃で２〜３時間処理した。Peel off the skin tissue of the hairless guinea pig,
Fat and muscle under the dermis are removed with tweezers, and dispase (Proteolytic enzyme manufactured by Godo Shusei Co., Ltd .: Bacillus polymixa) is immersed in phosphate buffered saline containing 1000 PU / ml, and the temperature is 2 to 37 ° C. Treated for 3 hours.
【００３２】人工光線源は Solar Light Co.社製のモデ
ル１４Ｓ型ソーラーシミュレーターを、紫外線強度計に
はトプコン社製のUVR-305/365D(III) ＵＶラジオメータ
ーを用いて測定を行った。尚、照射した紫外線の波長は
２９０〜４００ｎｍ（ＵＶＢ＋ＵＶＡ領域）、紫外線強
度は７ｍＷ／ｃｍ2、照射時間は５分間とした。The artificial light source was a Model 14S solar simulator manufactured by Solar Light Co., and the UV intensity meter was a UVR-305 / 365D (III) UV radiometer manufactured by Topcon. The wavelength of the irradiated ultraviolet rays was 290 to 400 nm (UVB + UVA region), the ultraviolet intensity was 7 mW / cm 2 , and the irradiation time was 5 minutes.
【００３３】上記ヘアレスモルモット表皮の表面側に、
第１の乳液を２ｍｇ／ｃｍ2となるように塗布した後、
同様に第２の乳液を塗布し、この膜を２ｃｍ×２ｃｍの
正方形の窓孔を有する７．６ｃｍ ×３．６ｃｍの長方
形のホルダーの窓孔に接着し、スタンドでこのホルダー
を垂直に保持した。On the surface side of the hairless guinea pig epidermis,
After applying the first emulsion to 2 mg / cm 2 ,
Similarly, a second emulsion was applied, and this film was adhered to the window of a 7.6 cm x 3.6 cm rectangular holder having a 2 cm x 2 cm square window, and this holder was held vertically by a stand. .
【００３４】この表皮の試料面にソーラーシミュレータ
ーの照射部を、他方の面に紫外線強度計の受光部をあ
て、試料及び表皮を透過する紫外線強度Ｅ（ｍＷ／ｃｍ
2）を測定した。一方試料を塗布しない膜を用いて同様
に紫外線強度Ｅ0）を測定し、Ｅ／Ｅ0をＳＰＦ値とし
た。使用した乳液の組合せと、評価結果を表２に示す。The irradiation part of the solar simulator is placed on the sample surface of this epidermis, and the light receiving part of the ultraviolet intensity meter is placed on the other surface, and the ultraviolet intensity E (mW / cm) that passes through the sample and the epidermis is set.
2 ) was measured. On the other hand, the ultraviolet intensity E 0 ) was similarly measured using a film on which the sample was not applied, and E / E 0 was taken as the SPF value. Table 2 shows the combination of emulsions used and the evaluation results.
【００３５】[0035]
【表２】 [Table 2]
【００３６】この結果から、ロズマリン酸を含む本発明
の化粧料は、ロズマリン酸を含まない比較例の化粧料に
比べて、紫外線防止効果に優れていることがわかる。ま
た、この効果はリジンを併用しなくても得られるが（使
用例６）、リジンを併用すると、さらに高い効果が獲ら
れることがわかる（使用例３）。From these results, it can be seen that the cosmetics of the present invention containing rosmarinic acid are superior in the anti-UV effect to the cosmetics of Comparative Examples containing no rosmarinic acid. Further, although this effect can be obtained without using lysine (Use Example 6), it can be seen that a higher effect can be obtained by using lysine in combination (Use Example 3).
【００３７】[0037]
【実施例６】次に、本発明の紫外線防止化粧料として、
クリームにおける実施例を説明する。[Embodiment 6] Next, as an ultraviolet protection cosmetic of the present invention,
An example of cream will be described.
【００３８】表３Ａ、Ｂの成分を、各々８０℃に加熱し
て溶解させて均一に混合した後、Ａの成分にＢの成分を
加え、撹拌して乳化させ、撹拌しながら３０℃まで冷却
する。The ingredients shown in Table 3A and B were heated to 80 ° C. to be melted and uniformly mixed, and then the ingredient B was added to the ingredient A, stirred to emulsify, and cooled to 30 ° C. with stirring. To do.
【００３９】[0039]
【表３】 [Table 3]
【００４０】[0040]
【実施例７】化粧水における実施例を説明する。表４Ａ
の成分を混合し、室温下で溶解する。これに、室温下で
溶解させたＢの成分を加えて可溶化する。[Embodiment 7] An embodiment of lotion will be described. Table 4A
The ingredients of 1 are mixed and dissolved at room temperature. The component B dissolved at room temperature is added to this to solubilize it.
【００４１】[0041]
【表４】 [Table 4]
【００４２】[0042]
【発明の効果】本発明の紫外線防止化粧料は、可視光短
波長領域を含め、ＵＶ−Ｂ領域を中心とした紫外線防止
効果を有する。さらに、皮膚角層中に紫外線防止作用を
有する層を形成し、この層の耐摩擦性、耐洗滌性に優れ
ており、持続性の良い紫外線防止効果を発揮することが
できる。EFFECTS OF THE INVENTION The anti-ultraviolet cosmetics of the present invention have an anti-ultraviolet effect mainly in the UV-B region including the visible light short wavelength region. Further, a layer having an ultraviolet ray-preventing action is formed in the stratum corneum of the skin, and this layer is excellent in abrasion resistance and washing resistance, and can exhibit a durable ultraviolet ray-preventing effect.
【図１】 ロズマリン酸の吸収スペクトルを示す図。FIG. 1 shows an absorption spectrum of rosmarinic acid.
Claims (2)
料全量に対し０．０１〜１０重量％含有する紫外線防止
化粧料。1. An anti-ultraviolet cosmetic containing rosmarinic acid or / and a salt thereof in an amount of 0.01 to 10% by weight based on the total amount of the cosmetic.
量に対し０．０１〜１０重量％含有する請求項１記載の
紫外線防止化粧料。2. The ultraviolet protective cosmetics according to claim 1, which contains 0.01 to 10% by weight of lysine and / or arginine with respect to the total amount of the cosmetics.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP30075492A JP3162513B2 (en) | 1992-11-11 | 1992-11-11 | UV protection cosmetics |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP30075492A JP3162513B2 (en) | 1992-11-11 | 1992-11-11 | UV protection cosmetics |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH06145034A true JPH06145034A (en) | 1994-05-24 |
| JP3162513B2 JP3162513B2 (en) | 2001-05-08 |
Family
ID=17888698
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP30075492A Expired - Fee Related JP3162513B2 (en) | 1992-11-11 | 1992-11-11 | UV protection cosmetics |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP3162513B2 (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0782127A (en) * | 1993-09-14 | 1995-03-28 | Kanebo Ltd | Cosmetic |
| JP2002212026A (en) * | 2001-01-18 | 2002-07-31 | Oriza Yuka Kk | Skin care preparation for beautifying skin |
| JP2003267857A (en) * | 2002-01-11 | 2003-09-25 | Mitsui Chemicals Inc | Skin care preparation and composition of skin care preparation |
-
1992
- 1992-11-11 JP JP30075492A patent/JP3162513B2/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0782127A (en) * | 1993-09-14 | 1995-03-28 | Kanebo Ltd | Cosmetic |
| JP2002212026A (en) * | 2001-01-18 | 2002-07-31 | Oriza Yuka Kk | Skin care preparation for beautifying skin |
| JP2003267857A (en) * | 2002-01-11 | 2003-09-25 | Mitsui Chemicals Inc | Skin care preparation and composition of skin care preparation |
Also Published As
| Publication number | Publication date |
|---|---|
| JP3162513B2 (en) | 2001-05-08 |
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