JPH05507276A - 動脈造影用合成ペプチド類 - Google Patents

動脈造影用合成ペプチド類

Info

Publication number
JPH05507276A
JPH05507276A JP91510596A JP51059691A JPH05507276A JP H05507276 A JPH05507276 A JP H05507276A JP 91510596 A JP91510596 A JP 91510596A JP 51059691 A JP51059691 A JP 51059691A JP H05507276 A JPH05507276 A JP H05507276A
Authority
JP
Japan
Prior art keywords
peptide
analog
amino acid
peptides
array
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP91510596A
Other languages
English (en)
Japanese (ja)
Inventor
リーズ,ロバート・エス
リーズ,アン・エム
フィッシュマン,アラン
シウ,イン―ラン
ファインディーズ,マーク・エイ
Original Assignee
ニュー・イングランド・ディーコネス・ホスピタル・コーポレイション
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ニュー・イングランド・ディーコネス・ホスピタル・コーポレイション filed Critical ニュー・イングランド・ディーコネス・ホスピタル・コーポレイション
Publication of JPH05507276A publication Critical patent/JPH05507276A/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10Organic compounds
    • A61K49/14Peptides, e.g. proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/775Apolipopeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00Preparations for testing in vivo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Obesity (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP91510596A 1990-05-03 1991-05-02 動脈造影用合成ペプチド類 Pending JPH05507276A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US51821590A 1990-05-03 1990-05-03
US51814290A 1990-05-03 1990-05-03
US518,215 1990-05-03
US518,142 1990-05-03
PCT/US1991/003026 WO1991016919A1 (fr) 1990-05-03 1991-05-02 Peptides synthetiques utilises en imagerie arterielle

Publications (1)

Publication Number Publication Date
JPH05507276A true JPH05507276A (ja) 1993-10-21

Family

ID=27059361

Family Applications (1)

Application Number Title Priority Date Filing Date
JP91510596A Pending JPH05507276A (ja) 1990-05-03 1991-05-02 動脈造影用合成ペプチド類

Country Status (5)

Country Link
EP (1) EP0600869A1 (fr)
JP (1) JPH05507276A (fr)
AU (1) AU663291B2 (fr)
CA (1) CA2080493A1 (fr)
WO (1) WO1991016919A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2004075925A1 (ja) * 2003-02-27 2006-06-01 株式会社産学連携機構九州 Mri用造影剤
JP2014508147A (ja) * 2011-02-08 2014-04-03 キングス・カレッジ・ロンドン 心血管イメージングに関連する材料および方法

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5972890A (en) * 1988-05-02 1999-10-26 New England Deaconess Hospital Corporation Synthetic peptides for arterial imaging
US5726153A (en) * 1988-05-02 1998-03-10 New England Deaconess Hospital Corporation Synthetic peptides for arterial imaging
US5997844A (en) * 1991-02-08 1999-12-07 Diatide, Inc. Technetium-99m labeled peptides for imaging
US5965107A (en) * 1992-03-13 1999-10-12 Diatide, Inc. Technetium-99m labeled peptides for imaging
US5989519A (en) * 1992-03-13 1999-11-23 Diatide, Inc. Technetium-99m labeled peptides for imaging inflammation
JPH07504902A (ja) * 1992-03-13 1995-06-01 ダイアタイド・インコーポレイテッド 炎症造影用のテクネチウム−99m標識ペプチド
US5733549A (en) * 1992-08-14 1998-03-31 Shino-Test Corporation Peptides including amino acid sequences selected from lipoprotein (a) and apolipoprotein (a), antibodies recognizing these amino acid sequences, and methods of determination using these antibodies
US5605671A (en) * 1992-10-05 1997-02-25 The Regents Of The University Of Michigan Radiolabeled neutrophil activating peptides for imaging
US5413778A (en) * 1992-10-05 1995-05-09 The Regents Of The University Of Michigan Labelled monocyte chemoattractant protein material and medical uses thereof
WO1994009128A1 (fr) * 1992-10-22 1994-04-28 Mallinckrodt Medical, Inc. Traitement therapeutique permettant d'inhiber la restenose vasculaire
DE4301871A1 (de) * 1993-01-13 1994-07-14 Diagnostikforschung Inst Neue Mittel zur Diagnose von Gefäßerkrankungen
DE4425778A1 (de) * 1994-07-13 1996-01-18 Diagnostikforschung Inst Komplexverbindungen zur Diagnose von Gefäßerkrankungen
US6489446B1 (en) 1996-08-07 2002-12-03 Hsc Research And Development Limited Partnership Self-aligning peptides modeled on human elastin and other fibrous proteins
JP2001505539A (ja) * 1996-08-07 2001-04-24 プロテイン・スペシャルティーズ,リミテッド エラスチン及び他の線維状タンパク質由来の自己整列ペプチド
US6632923B1 (en) 1996-11-27 2003-10-14 Boston Heart Foundation, Inc. Low density lipoprotein binding proteins and their use in diagnosing and treating atherosclerosis
ATE317264T1 (de) 1996-11-27 2006-02-15 Boston Heart Foundation Inc Neue low density lipoprotein bindende proteine und deren verwendung in der diagnostik und behandlung von atherosklerose
US6605588B1 (en) 1996-11-27 2003-08-12 Boston Heart Foundation, Inc. Low density lipoprotein binding proteins and their use in diagnosing and treating atherosclerosis
US8119598B2 (en) 2007-05-10 2012-02-21 Hospital For Sick Children Synthetic peptide materials for joint reconstruction, repair and cushioning
WO2023086771A2 (fr) * 2021-11-05 2023-05-19 Trustees Of Tufts College Matériaux pour la récupération de métaux de valeur

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1242643A (fr) * 1983-08-12 1988-10-04 Eric T. Fossel Imagerie medicale par rmn faisant appel a des reactifs provoquant des deplacements chimiques
US4643988A (en) * 1984-05-15 1987-02-17 Research Corporation Amphipathic peptides
EP0209543A4 (fr) * 1984-12-31 1989-07-11 Internat Genetic Engineering I Fragments de peptides d'apolipoproteines humaines, anticorps specifiques du type et procedes d'utilisation.
US4660563A (en) * 1984-12-31 1987-04-28 Massachusetts Institute Of Technology Method and means for detection of arterial lesions
US4976734A (en) * 1985-10-31 1990-12-11 Uab Research Foundation Stimulation of chemotaxis by chemotactic peptides
WO1989010760A1 (fr) * 1988-05-02 1989-11-16 New England Deaconess Hospital Corporation Peptides synthetiques pour imagerie arterielle

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2004075925A1 (ja) * 2003-02-27 2006-06-01 株式会社産学連携機構九州 Mri用造影剤
JP2014508147A (ja) * 2011-02-08 2014-04-03 キングス・カレッジ・ロンドン 心血管イメージングに関連する材料および方法

Also Published As

Publication number Publication date
EP0600869A1 (fr) 1994-06-15
EP0600869A4 (fr) 1993-03-22
CA2080493A1 (fr) 1991-11-04
WO1991016919A1 (fr) 1991-11-14
AU7992891A (en) 1991-11-27
AU663291B2 (en) 1995-10-05

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