JPH05506453A - Pest control formulations - Google Patents

Abstract

(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.

Description

[Detailed description of the invention] The invention relates to light-sensitive or photosensitive substances, especially pesticidal agents. de) and (or) for stabilizing synergists for pesticides and herbicides. The present invention relates to formulations and the use of such formulations in the control of pests.

European Patent No. 85805B contains microbial capsules, in particular yeast capsules. Discloses encapsulated materials and methods of making such encapsulated materials This encapsulated material is made of an organic fat in which the material to be encapsulated is soluble. Treating the growing microorganisms with the bulking material and simultaneously and/or subsequently Formed by contacting the organism with the substance to be encapsulated. and Although this encapsulation method is particularly suitable for the production of encapsulated dyes, Other examples of substances that should be classified include adhesives, adhesive ingredients, pharmaceuticals, fragrances, rodenticides, Insecticides, herbicides, fungicides and odorants are listed as being included.

European Patent Specification No. 242135A describes a modification of this microbial encapsulation technique. Discloses the law. In this method, grown and untouched microorganisms are released into liquid capsules. The encapsulatable material is treated with an encapsulatable material, whereby the encapsulatable material is completely free of microorganisms. This method is used to increase lipid content (diffusion into microbial cells) without causing lysis. carried out in the absence of material (as specified in European Patent No. 85805B). be exposed. The products of this encapsulation method are typically Control that is stable and useful for administering pharmaceuticals, pheromones and pest control agents It is described as providing a product with controlled release characteristics. However, light absorbers or can encapsulate a substance without the addition of other substances such as light scattering agents. Who would say that it is possible to reduce the sensitivity of a substance to light (i.e., its photosensitivity) just by I didn't understand either.

Here, the synergist piperonyl butoxide and the insecticide extracted from pyrethrum ( Light-sensitive or photosensitive substances such as pyrethrins) are encapsulated in the yeast. As a result, its photosensitivity is considerably low, making it unsuitable for applications that could not be used before. It was discovered that it could be done.

Here, a photosensitive substance is a substance that decomposes quickly when exposed to sunlight and generally Substances with a half-life of less than 5 hours when measured under test conditions; In short, substances with a half-life of less than 1 hour, especially those with a half-life of less than 40 minutes. It is a substance. Generally, the uses of photosensitive materials are limited by their photosensitivity. suitable The typical test conditions involve applying the substance onto an inert surface (e.g. glass) and controlling its deposits. Provided by exposure to controlled artificial light conditions. suitable artificial sunlight The light source is a "Hanau Suntester" as described below. lamps, accelerated exposure table units).

Accordingly, the present invention provides a formulation comprising a photosensitive active ingredient encapsulated in yeast. do. Preferably, the photosensitive active ingredient is a photosensitive insecticide encapsulated in yeast. or a synergist for a photosensitive herbicide or an insecticide, or a synergist for a herbicide. Preferably The photosensitive insecticide has a half-life of less than 40 minutes and is a member of the pyrethrin family of insecticides. Ru. Other insecticides that can be advantageously included in the formulations of the invention include It has a half-life of allethrin and nisbiothrin), resmethrins (e.g. resmethrin and nisbiothrin), olemethrin), lipid amides (e.g. European Patent No. 0369762, No. 111105, No. 164187, No. 194764, No. 209289, No. 225011, No. 251472, No. 269457 and No. 317188 pyrethroids (such as those described in ) as well as some degree of photostability Pyrethroids such as vermethrin, alpha-cypermethrin and deltamethrin includes.

A preferred photosensitive herbicide is trifluralin. The preferred rodenticide is cholecalcifero. Preferably, the synergist for insecticides or herbicides is Vitamin D. peronylbutoxide (5-[2-(2-butoxyethoxy)ethoxymethyl]- 6-broby-1,3-benzodioxole), preferably encapsulated The substances used are piperonyl butoxide or its combination with pyrethrum extract or allethrin. It is a mixture with insecticides. Preferably, herbicides or insecticides or herbicides or insecticides Synergists for drugs are described in European Patent Application No. 242135A or European Patent No. It is encapsulated in yeast by the method described in No. 858058B.

The exact amount of encapsulated material to be applied to a given location depends on the pest being controlled. the specific activity of the substance against the plant or weed species, the method of application and the nature of the formulation to be applied; Depends on quality and whether piperonyl butoxide is included in the formulation. However, in general, the following amounts of pyrethrin can be applied: 50 to 300 g/ hectare (2-10 oz/neeker), piperonyl butoxide 50-12 00g/ha (0,125-3 bonds/knee car), lipid amides 5-1 50 g/ha (0.0125-0.4 bond/knee car).

The formulations of the invention may be prepared using a powdered solid inert carrier, such as a suitable resin, kaolin, etc. Bentonite, Attapulgite, Absorbent Carbon Black, Talc, Mica , graphite, gypsum, phosphorus tricalcium, powdered cork, magnesium silicate, vegetable Can be applied as a solid formulation mixed with carriers, starch, diatomaceous earth etc. can.

Wettable powders include an inert solid carrier, one or more surfactants as optional ingredients and ( or) contains stabilizers and/or antioxidants.

Wettable powders usually contain from 5 to 95% by weight of active ingredient and are diluted, e.g. with water, before use. be interpreted.

Aqueous suspensions of the formulations of the invention can be prepared in water with suspending agents, stabilizing agents or other agents. It may consist of suspended matter! ! The suspension or solution can be used as is or in a known manner. It can be applied in diluted form in the following manner.

Aerosol spraying involves adding the active ingredient to water with an aerosol propellant, such as carbon dioxide. It can be produced as a suspension in the presence of Pukuon formulation is originally from A clear formulation can be prepared as a suspension in water.

Poison baits can be prepared by mixing them with additional edible substances in a suitable binding matrix. formulations of the invention.

The formulations of the invention are suitable for pests such as arthropods (insects and mites) and rodents. It can be used to exterminate things.

Accordingly, the present invention provides a pest control formulation of the present invention in an amount effective to control pests. to harmful organisms such as arthropods or rodents or to the environment in which they live. To provide a method for controlling pests such as arthropods or rodents that consists of Ru. The present invention also provides for administering an effective amount of the arthropod control formulation of the present invention to an animal or a predetermined target. animals and/or plants (including trees) and/or storage A method for controlling and/or eradicating arthropod infestation of stored products is provided. difference Additionally, the present invention is useful for human and animal treatment, public health management, and agriculture. A pest control formulation is provided for use in controlling pest control organisms.

The formulations of the invention can also be used to control weeds.

Therefore, the present invention provides a herbicidally effective amount of the herbicide formulation of the present invention to To provide a weed control method comprising administering these to an environment infested with these weeds.

The insecticide formulations of the invention can be used in fields, pastures, plantations, greenhouses, orchards and vineyards. It is particularly effective for protecting trees, shrubs, ornamental plants, plantations and forests; Examples of these include 1. Cereals (corn, wheat, rice, corn) , cotton, tobacco, vegetables and salad vegetables (legumes, oilseed crops, cucumbers, lettuce) crops (e.g. potatoes, sugar beets, peanuts), farm crops (e.g. potatoes, sugar beets, peanuts) , soybeans, rapeseed), sugar cane, greenhouse and pasture crops (e.g. corn) (e.g. tea, coffee, cocoa, banana), plantations (e.g. tea, coffee, cocoa, banana fruit, oil palm, coconut, rubber, spices), orchards and forests (e.g. stone fruit, Citrus fruits, keelai fruits, avocados, mangoes, olives, walnuts), grapes Gardens, ornamental plants, flowers and shrubs indoors, gardens and parks, forests, farms and seedlings There is protection of trees in the field (both deciduous and evergreen).

They also use wasps (Urocera Urocerus) or beetles (e.g. scolytides, platypods, livids) protects against attacks by ectids, bostritides, cerambicids, and anovides). It is effective for

In addition, they are used in storage products such as grains, fruits, nuts, spices and tobacco. moths, whether whole, ground or formulated into products; Useful in protecting against attack by beetles and ticks.

Protection also applies to stored animal products, such as skin, hair, wool and natural attack of treated leather (e.g. carpets or textiles) by moths and beetles; and protection of stored meat and fish from attack by beetles, mites and flies. Ru.

Therefore, the insecticide composition of the present invention can kill arthropods such as insects and mites. in any environment where the animal is a pest, e.g. in agriculture, animal husbandry, public health management and Useful for extermination in domestic and domestic environments.

Insect pests include many Coleoptera (e.g. Anobiug). , Ceuthorrhynchus, Rhynchophorus (Rh ynchophorus), cosmopolites ((:og+mopolites ), Li5sorhoptrus, Meli gethes), Hypothenemus, Hyrecinus ( HyLesinua), Acalyma+a, Lea +a), Psylfodes, Lep tinotarsa), Gonocephalum, a Agriotes, Dermolepida ), Heteronychus, Phaed on), Tribolium, Sitophilus (5itophi lus), Diabrotica, Ant hono+nus) or Anthrenus (Anthrenus 5pp)) , Plioptera (e.g. Ephestia, Mames tra), Nearias, Pectinophora phora), Ostrinia (Ostrinia), Trichobrusia (Tri choplusia), Pieris, Laph ygma), AgrotiS, Amathes , Wiseana, Tryporyza , Diatraea, Sparganothi s), Cydia, Archips, Pulte PLutella, CMlo, % Heliosis hLs), Subodoptera, or Ti neola 5pl))) + Diptera (e.g. Musca) , Aedes, 7 Anophele-s, Cu Lettuce (Cu1ex), Glossina, N Simurium (Si mulium), Stomoxys, Haematobia matobia), Tabanus, Hydrothea taea), Luctlia, Chrysomia omyLa), Callitroga, Del Madovia (De rmatobia), Gasterophilus, Hypoderma, Hylemyia, Atherigona, Chlorops, Phytomyza, Ceratitis , Liriomyza, Melophagus usspp), Phytilabutera (Mallophaga) (e.g. For example, Damalina (Damalina 5pp)), Liceformes (e.g. Linognathus, Haen+atap inusspp)), Hemiptera (e.g. Aphis), Bemis Bemisia, Pholodon, Eneolami A (^eneolaa+ia), empoagca (εmpoagca), pal Parkingiella, Pyrilla, Ao Aonidiella, Coccus, Shuudo Pgeudococcus, He1opelti s), Lygus, Dy5dercus, Oxy Oxycarenus, Nezara, Arelode Su (^1eyrodes), Triatoma (Triatoma), Cyra ( Psylla), Myzus, Megoura, Fu Phylloxera, Adelges, Leek Ni1aparvata, Nephroteticus tix) or Cimex (Cimex spp)), Orthoptera (e.g. Locusta, Gryllus, Cyst Cell Force ( 5 chistocerca) or Acheta (5pp)), Hymenoptera (e.g. Blattella, Perip laneta) or Blatta 5pp)), Hymenoptera (e.g. For example, Athalia, Cephus, Atta (Atta), Thulenopsis (5o1enopsis) or Monomolyrum ( Monomorium (5pp)), Isoptera (e.g. Odontotermes (Odo ntotermes), Reticuliter+ses 5pp)), Microptera (e.g. Ctenocephalides) idas) or Pulex spp)), or Pulex spp. Lepisma (Lepisma spp)), Hymenoptera (e.g. Forficula Spp) Peripsocus 5pp)), Hymenoptera (e.g. Thrilus tapasi ( Thrfps tabaci)) is included.

Pests of ticks include ticks, e.g. lambda, many genera, e.g. illus), Ornithodorus, Ribisef Rhipicephalus, Amblyomm a), Hyaloma, Ixodes, Haemaphysalis, Der* acsntor), Anocentor, Might and Manges, such as Acarus, Tetra Tetranychus, Psoroptes, No. Notoednes, Sarcoptes , Psorergates, Chorio ptes), Eutrombicula s-9, Demode Demodex, Panonychus, Brio Bia (8ryobia), Er1ophyes (Er1ophyes), Burani Blaniulus, Polyphagus otarsonemus).

Scutigerella, 0niscuss pp) is included.

The formulations of the invention contain a suitable larvicide, such as vermethrin. It can be used to kill larvae in bait form.

The formulations of the present invention containing rodenticides can be used to control rodents. can.

The invention will be explained in detail by the following examples.

Examples 1 to 7 are formulations according to the invention and the yeast encapsulation method followed in these examples was As described in European Patent No. 242135, the substance to be encapsulated was mixed with yeast in a liquid medium. Example 8 shows pipero encapsulated in yeast cells. Example 9 showing the results of a test to determine the photostability of nilbutoxide is a cockroach. The results of biological tests are shown.

・Biperonyl butoxy encapsulated with Base m second! Pyrethrum paleo 25% 10.8 piperonyl butoxide (PBO) 29.3 Baker's Yeast 56.0 Synthetic silica 3.9 (For example, Shiba-Nut 22S5) This formulation is made from the concentrate described below.

l engineering A 11KLl! Every leaf of pyrethrum 25% 4.6 PB0 11.5 Baker's Yeast 30.1 Water 53.5 Preservative 0.3 The above concentrated liquid is mixed with fumed silica (e.g. Kabuosil M5) and water in the following ratio. The formulation is made by mixing in a spray dryer and then passing the formulation through a spray dryer.

tm engineering 11 Concentrated liquid 24.8 Power Buosil M5 1.0 Wednesday 74.2 Takumi l of piperonyl butoxide encapsulated with The following concentrates are combined with fumed silica (e.g. Kabuosil M5) and water as shown in Example 1. Make the formulation by mixing in the proportions.

l engineering 1 11 and 211 Every leaf of pyrethrum 25% 10.8 PBo　29.3 Baker's yeast 52.8 Silica (Kabuosil M5) 7.0 Preservative 0.1 Examples 1 and 2 are examples in which addition of up to 0.7 C of active ingredient per 1 C of yeast can be applied. be.

Legend].

Mr. Nimus Kyojidanl (hydrating agent) 11th grade 11 Bakers Yeast 80.1 Preservative (formalin) 0.1 This is used to prepare a vermethrin concentrate (no anticaking agent required) as shown below. The product was prepared by preparing and drying.　m2l! Baker's Yeast 38.5 Water 35.7 Preservative (formalin) 0.3 "Kari".

1 (manufactured from the powder concentrate of Example 3) 1111 No. 11 Vermethrin (industrial grade) 0.5 Solvent (C, alcohol, Aramazol H) 0.2 Baker's yeast 1.4 Silica (Kabuosil 5) 1.8 Talc 96.1 Pan 1 medical doctor Various dilutions may be required depending on the final concentration. Yeast tends to settle and therefore Suspending agents can be used.

10% dilution 115 11 Yeast concentrate (turnip with 14% yeast) Cellified vermethrin, e.g. 6) 10.0 suspending agents (e.g. bioanti, Santan gum, Keltrol) 0.3 Wednesday 89.6 Preservative 0/1 (For example, pronidox L (propylene of 5-bromo-5-nitro-1,3-dioxane) (ropylene glycol solution), Proxel GXL (approximately 20% 1,2-benzoylene aqueous diisopropylene glycol solution of sothiazolin-3-one (BIT), or formalin) The amount of suspending agent will vary depending on the type used. This dilution can be left as is or treated separately. For example, it can be used as part of an aerosol.

Takumi Hiroshi aerosol Minister J Koyuri Otsu! i) Yeast concentrate (e.g. 14% bar) Methrin (see below) 9.8 Wetting agents (e.g. silicone wetting agents) Tego Plant WT25) o, 1 ii) Yeast concentrate (e.g. vermethrin encapsulated with 14% yeast) See below) 60.0 Butane 40 40.0 1.1 (14% yeast encapsulated methrin) 1120L Otsu! Vermethrin 14.0 Aromatic solvent (Aramazol H) 9.4 Preservatives (formalin, Proxel GXL or Pronidox L) 0.31 rin Approximately m-2 i) Magnesium aluminum silicate (low grade mica), e.g. barmesli concentrated liquid (see below), 4 1 work 1 11 亙 2 Zma Baker's yeast 28,5 Water 57.0 Antifoam agent (e.g. Silicorapse 5000) 0.1ii) Another base matrix ” 15 elma Soybean powder 20.0 Fuitsyumir 20.0 Sugar 20.0 Parafine wax 11.0 Soybean oil 20.0 Yeast concentrate 9.0 The larvicides are prepared as diluted concentrated samples, i.e. up to 40% active ingredient/solvent mixture. or with a low degree of encapsulation, e.g. below 1-2% (vermethrin). It can be used with the active ingredients.

``Medicine.''

A. Stability on glazed tiles To determine the photostability of piperonyl butoxide encapsulated in yeast cells A test was conducted. The following method is used for piperonyl butoxide/pyrethrin mixtures and It was also applied to photostable pyrethroids.

Mu piperonyl butoxide content (or piperonyl butoxide/piperonyl butoxide) A water dilution was prepared to give 20 mg/ml) in the surin formulation. 10.5 Draw a 6cm circle on a glazed white ceramic tile of 10.5cm x 0.5m. 1 of the well-mixed suspension was uniformly deposited within the drawn circle by a bed.

The tiles were left to dry on a flat surface overnight.

The tile is then placed in the Helios Sunset Lamp (Hanau Sun Tester) and Water cooled to obtain a maximum temperature of 30°C, exposed for a predetermined precise time and recorded. Ta.

The light on the tile surface was so, ooo lux, 2.5 mW/cm” UVA. . Remove the tile from the lamp and remove any deposits with a small cotton swab dipped in methanol. I left.

Transfer these to a 50 ml Erlenmeyer flask with a stopper, and evaporate the methanol with a stream of air. Ta. Pipette 10 ml of methanol onto the deposit and place in an ultrasonic bath for 5 minutes. It was.

The resulting solution was filtered and subjected to GLC analysis in 0.02% piperonyl butoxide. Comparison was made with the chromatogram of the liquid.

Also, add 0.5 ml of 0.6% industrial piperonyl butoxide solution in a 6 cm circle. A control test was also conducted by applying and conducting the test as described above.

The pyrethrin/PBO samples used were as follows.

Company L Pyrethrum per leaf 25% 5,5 (10% of total unencapsulated part) PBo 13.5 (16% of total unencapsulated portion) Baker's yeast 35.6 Water 45.4 The vermethrin/PBO sample used was as follows: Vermethrin 8.0 ( 7,8% internal) PBO8, O (7,4% internal) Yeast 28.5 Water 55.5 ■ UV stability test results for pyrethrin/PBO and vermethrin/PBO samples Table 1 below. It is shown in Table 2 and Table 3.

B. Stability on glass encapsulated in yeast to determine the overall profile of stability on glass. Tests were conducted on piperonyl butoxide. Experiment A above was carried out using capsules in yeast. was shown to increase the half-life of PBO when applied to glazed tiles. However, the value was not determined. This experiment was carried out to determine the half-life (T=y) for the formulation used. value).

Sample: Piperonyl butoxide in Baker's yeast (22.1% w/w internal, 0.7% w / w external) Wataru The formulation was diluted with water and applied to glass plates at a rate of 50 mg per plate. dilution is applied as a droplet to the board surface, allowed to dry and then placed under a suntest lamp for 36 hours. spaced apart. Then, calculate the total amount of remaining PBO as outlined in A above. determined using the method. The results are listed in Table 4 below.

A Application amount 0.14mg/6cm plate = 50　m　g　/　m”■ PBQ T, encapsulated in yeast. The value is approximately 35 hours.

A typical value for a control example is about 30 minutes.

Takumi Dan Contains 4.5% technical grade pyrethrin and 13.5% piperonyl butoxide A formulation similar to Example 1 or 2 was prepared. A series of dilutions was made ranging from 0.2 to 0. A solution containing 0.2% (W/V) pyrethrin was obtained. 0 of these solutions ．． 5 ml portions were applied to the surface of the glazed tiles.

Cockroaches (male, Blatalla germanica) were treated with these formulations. 5% pyrethrin exposure for 30 seconds and mortality recorded after 6 days. and pyrethrin/pyrethrin, an emulsifying concentrated rhinoceros solution containing 50% piperonyl butoxide. Mortality rates were compared to that of a peronyl butoxide formulation (pyrethrin 5150EC).

The results are shown in Table 5 below.

■ abstract Te 1 Photosensitive insecticide or herbicide or photosensitive insecticide or photosensitive herbicide Formulations of synergists encapsulated in yeast and insects and mites Describe the use for extermination of pests and rodents.

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Claims (11)

[Claims] 1. A formulation consisting of a photosensitive active ingredient encapsulated in yeast. 2. Photosensitive insecticide or photosensitive herbicide or photosensitive insecticide or photosensitive herbicide A formulation consisting of a synergist encapsulated in yeast. 3. The photosensitive insecticide is one of the birethrin and/or photosensitive pyrethroid insecticides. 3. The formulation according to claim 2. 4. A photosensitive pyrethroid is one of the allethrin or resmethrin insecticides. The formulation according to claim 3. 5. Claims 1 to 4 containing lipid amide, vermethrin or deltamethrin A formulation according to any of the above. 6. The above claims wherein the synergist for insecticides or herbicides is piperonyl butoxide. A formulation according to any of the above. 7. The substance to be encapsulated together with pyrethrum extract or one of the allethrin insecticides according to any of the preceding claims, wherein the piperonyl butoxide is encapsulated. formulation. 8. The photosensitive active ingredient is prepared by mixing yeast with the photosensitive active ingredient in a liquid medium. A formulation according to any of the preceding claims, wherein the ingredients are encapsulated in yeast. 9. Spray-dried formulations, concentrates, powders, dusts, aqueous suspensions, aerosols or baits A formulation according to any of the preceding claims in the form of. 10. Photosensitizer encapsulated in yeast in an effective amount for pests or the environment in which they live. A method of exterminating pests by administering a pesticide. 11. encapsulated in an effective amount of yeast to the weed or the environment infested with it. A method of controlling weeds by administering photosensitive herbicides.