JPH0542203A - Connection method for medical tube - Google Patents

Connection method for medical tube

Info

Publication number
JPH0542203A
JPH0542203A JP3223465A JP22346591A JPH0542203A JP H0542203 A JPH0542203 A JP H0542203A JP 3223465 A JP3223465 A JP 3223465A JP 22346591 A JP22346591 A JP 22346591A JP H0542203 A JPH0542203 A JP H0542203A
Authority
JP
Japan
Prior art keywords
tube
bag
blood
polyvinyl chloride
flow port
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP3223465A
Other languages
Japanese (ja)
Other versions
JP3092674B2 (en
Inventor
Keitaro Shimoda
啓太郎 下田
Giichi Shirasaki
義一 白崎
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nissho Corp
Original Assignee
Nissho Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nissho Corp filed Critical Nissho Corp
Priority to JP03223465A priority Critical patent/JP3092674B2/en
Publication of JPH0542203A publication Critical patent/JPH0542203A/en
Application granted granted Critical
Publication of JP3092674B2 publication Critical patent/JP3092674B2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C65/00—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
    • B29C65/48—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor using adhesives, i.e. using supplementary joining material; solvent bonding
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/01—General aspects dealing with the joint area or with the area to be joined
    • B29C66/05—Particular design of joint configurations
    • B29C66/10—Particular design of joint configurations particular design of the joint cross-sections
    • B29C66/11—Joint cross-sections comprising a single joint-segment, i.e. one of the parts to be joined comprising a single joint-segment in the joint cross-section
    • B29C66/112—Single lapped joints
    • B29C66/1122—Single lap to lap joints, i.e. overlap joints
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/50—General aspects of joining tubular articles; General aspects of joining long products, i.e. bars or profiled elements; General aspects of joining single elements to tubular articles, hollow articles or bars; General aspects of joining several hollow-preforms to form hollow or tubular articles
    • B29C66/51—Joining tubular articles, profiled elements or bars; Joining single elements to tubular articles, hollow articles or bars; Joining several hollow-preforms to form hollow or tubular articles
    • B29C66/52—Joining tubular articles, bars or profiled elements
    • B29C66/522—Joining tubular articles
    • B29C66/5229—Joining tubular articles involving the use of a socket
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/50—General aspects of joining tubular articles; General aspects of joining long products, i.e. bars or profiled elements; General aspects of joining single elements to tubular articles, hollow articles or bars; General aspects of joining several hollow-preforms to form hollow or tubular articles
    • B29C66/51—Joining tubular articles, profiled elements or bars; Joining single elements to tubular articles, hollow articles or bars; Joining several hollow-preforms to form hollow or tubular articles
    • B29C66/53—Joining single elements to tubular articles, hollow articles or bars
    • B29C66/532—Joining single elements to the wall of tubular articles, hollow articles or bars
    • B29C66/5326—Joining single elements to the wall of tubular articles, hollow articles or bars said single elements being substantially flat
    • B29C66/53261—Enclosing tubular articles between substantially flat elements
    • B29C66/53262—Enclosing spouts between the walls of bags, e.g. of medical bags
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/50—General aspects of joining tubular articles; General aspects of joining long products, i.e. bars or profiled elements; General aspects of joining single elements to tubular articles, hollow articles or bars; General aspects of joining several hollow-preforms to form hollow or tubular articles
    • B29C66/51—Joining tubular articles, profiled elements or bars; Joining single elements to tubular articles, hollow articles or bars; Joining several hollow-preforms to form hollow or tubular articles
    • B29C66/53—Joining single elements to tubular articles, hollow articles or bars
    • B29C66/534—Joining single elements to open ends of tubular or hollow articles or to the ends of bars
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/50—General aspects of joining tubular articles; General aspects of joining long products, i.e. bars or profiled elements; General aspects of joining single elements to tubular articles, hollow articles or bars; General aspects of joining several hollow-preforms to form hollow or tubular articles
    • B29C66/51—Joining tubular articles, profiled elements or bars; Joining single elements to tubular articles, hollow articles or bars; Joining several hollow-preforms to form hollow or tubular articles
    • B29C66/53—Joining single elements to tubular articles, hollow articles or bars
    • B29C66/534—Joining single elements to open ends of tubular or hollow articles or to the ends of bars
    • B29C66/5344—Joining single elements to open ends of tubular or hollow articles or to the ends of bars said single elements being substantially annular, i.e. of finite length, e.g. joining flanges to tube ends
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C59/00—Surface shaping of articles, e.g. embossing; Apparatus therefor
    • B29C59/14—Surface shaping of articles, e.g. embossing; Apparatus therefor by plasma treatment
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C65/00—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
    • B29C65/48—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor using adhesives, i.e. using supplementary joining material; solvent bonding
    • B29C65/4805—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor using adhesives, i.e. using supplementary joining material; solvent bonding characterised by the type of adhesives
    • B29C65/483—Reactive adhesives, e.g. chemically curing adhesives
    • B29C65/4835—Heat curing adhesives
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/01—General aspects dealing with the joint area or with the area to be joined
    • B29C66/02—Preparation of the material, in the area to be joined, prior to joining or welding
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/70—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material
    • B29C66/71—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the composition of the plastics material of the parts to be joined
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2023/00—Use of polyalkenes or derivatives thereof as moulding material
    • B29K2023/04—Polymers of ethylene
    • B29K2023/06—PE, i.e. polyethylene
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2027/00—Use of polyvinylhalogenides or derivatives thereof as moulding material
    • B29K2027/06—PVC, i.e. polyvinylchloride
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00—Other particular articles
    • B29L2031/712—Containers; Packaging elements or accessories, Packages
    • B29L2031/7148—Blood bags, medical bags

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • External Artificial Organs (AREA)

Abstract

PURPOSE:To prevent, in the noted connection method for blood-gathering-bags, blood from being leaked upon centrifugation by using in advance plasma to process the bonded surface of a polyolefine tube in order to connect to a soft polyvinyl chloride tube which contains no plasticizers. CONSTITUTION:A bag main body 1 comprising a mixture of poly (ethylene) polystyrene block copolymers, polypropylene, and ethyleneethylacrylate copolymers is thermally fused with a flow port comprising the same components. Plasma is used to process the flow port 4 before a flow tube 3 is connected to it. On the other hand, the flow tube 3 is formed of soft vinyl chrolide which contains no plasticizers. Then the flow tube 3 is connected to the flow port 4 which has been processed with plasma using epoxy resin.

Description

【発明の詳細な説明】Detailed Description of the Invention

【０００１】[0001]

【産業上の利用分野】本発明は、採血バツグ用などの医
療用チユーブの接続方法に関する。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a method for connecting a medical tube such as a blood collecting bag.

【０００２】[0002]

【従来の技術】供血者から血液を採集する場合、全血液
の細胞成分は通常貯蔵及び使用に先だって血漿部分から
分離される。分離は沈降により、あるいは最も頻繁には
遠心分離により行われ、これにより上部血漿層・白血球
とおそらくは血小板を含有する中間の薄い層（いわゆる
軟膜層）および赤血球の下部層を生ずる。血液成分の採
集・分離・貯蔵のための多くの各種方法及び装置が知ら
れている。現在最もよく使用されているのは採血バツグ
と少なくとも一つの移行バツグからなる周知のマルチプ
ル血液バツグである。BACKGROUND OF THE INVENTION When collecting blood from a donor, the cellular components of whole blood are usually separated from the plasma portion prior to storage and use. Separation is performed by sedimentation, or most often by centrifugation, which results in an intermediate thin layer (so-called buffy coat) containing the upper plasma layer-white blood cells and possibly platelets and the lower layer of red blood cells. Many different methods and devices for collecting, separating and storing blood components are known. Presently most commonly used is the well-known multiple blood bag consisting of a blood collection bag and at least one transfer bag.

【０００３】採血バツグは可塑剤入りのポリ塩化ビニル
からできている。この素材からなる血液バツグは血液及
び血液成分の貯蔵及び処理に極めて良く役立ち、例えば
２１日貯蔵後において低い血漿ヘモグロビン含量のもと
に高い生存率を示してきた。The blood collection bag is made of polyvinyl chloride containing a plasticizer. A blood bag made of this material is extremely useful for storing and processing blood and blood components, and has shown high survival rate, for example, after storage for 21 days with a low plasma hemoglobin content.

【０００４】移行バツグは良好な二酸化炭素移動特性を
示す素材からできている。この素材の例としてポリオレ
フインが挙げられる。The transfer bag is made of a material that exhibits good carbon dioxide transfer properties. An example of this material is polyolefin.

【０００５】このように採血バツグと移行バツグとは、
各バツグ素材が移行及び採血バツグの特定機能に有益な
効果をもたらすように特別に選定された異種の性質を発
揮するように、それぞれ異種のポリマー組成物よりなる
プラスチツク材料で作られる。As described above, the blood collection bag and the migration bag are
Each plastic material is made of a plastic material, each composed of a different polymer composition, so that it exhibits different properties that are specifically selected to have a beneficial effect on the specific function of the migration and blood collection bags.

【０００６】採血バツグと移行バツグは、それらの間に
シールされた流体の連通を提供する導管手段によって連
結されている。バツグと連通管との連結はバツグに設け
られた流通口に連通管を突き合わせその外周に接合管を
密着させる方法が多く、この密着には接着剤が用いられ
る。The blood collection bag and the transfer bag are connected by conduit means which provide a sealed fluid communication therebetween. The connection between the bag and the communication pipe is often done by abutting the communication pipe to a flow port provided in the bag and closely adhering the bonding pipe to the outer periphery thereof, and an adhesive is used for this adhesion.

【０００７】この連通管の素材は製造工程・バツグと連
通管との連結強さを考慮して、採血バツグの素材又は移
行バツグの素材と同じであることが好ましく、なかでも
採血バツグの素材と同じ場合が一般的である。The material of the communicating pipe is preferably the same as the material of the blood collecting bag or the material of the transferring bag in consideration of the manufacturing process, the connection strength between the bag and the communicating pipe, and in particular, the material of the blood collecting bag is The same case is common.

【０００８】[0008]

【発明が解決しようとする課題】このようなマルチバツ
グに供血者から血液を採集し、遠心分離操作を行うと、
バツグに設けられた流通口と連通管の接続部で血液が漏
れるという問題がしばしば発生する。これは接続部が特
に異種の素材からなる場合、例えば採血バツグと連通管
がポリ塩化ビニルからなり、移行バツグとそれに設けら
れた流通口がポリオレフインからなる場合に、流通口と
連通管の間で見られる。When blood is collected from a donor in such a multi-bag and subjected to a centrifugation operation,
A problem often arises that blood leaks at the connection between the flow port and the communication pipe provided in the bag. This is because when the connecting part is made of a different kind of material, for example, the blood collecting bag and the communication pipe are made of polyvinyl chloride, and the transfer bag and the flow port provided therein are made of polyolefin, the connection between the flow port and the communication pipe is made. Can be seen.

【０００９】本発明はこのマルチバツグの遠心分離時の
血液の漏れを解決するためになされたものである。The present invention has been made to solve the leakage of blood during centrifugal separation of the multi-bag.

【００１０】[0010]

【課題を解決するための手段】本発明は，ポリオレフイ
ンチユーブとポリ塩化ビニルチユーブを接着剤で接合す
るに際し、ポリオレフインチユーブの接着面にあらかじ
めプラズマ処理をなし、かつ、ポリ塩化ビニルチユーブ
には無可塑剤軟質ポリ塩化ビニルを使用することを特徴
とする医療用チユーブの接続方法を要旨とする。SUMMARY OF THE INVENTION According to the present invention, when a polyolefin inch tube and a polyvinyl chloride tube are bonded with an adhesive, the adhesive surface of the polyolefin inch tube is preliminarily subjected to plasma treatment, and the polyvinyl chloride tube is not plasticized. A gist is a method of connecting a medical tube, which is characterized by using a soft polyvinyl chloride agent.

【００１１】本発明において無可塑剤軟質ポリ塩化ビニ
ルとはポリ塩化ビニルに可塑剤を含有させておかないも
ののことである。In the present invention, the non-plasticizer soft polyvinyl chloride is one in which polyvinyl chloride does not contain a plasticizer.

【００１２】[0012]

【作用】本発明は，医療用チユーブであって遠心分離の
ような過酷な条件の操作を受けても接続部における剥離
がみられないように、ポリオレフインチユーブとポリ塩
化ビニルチユーブを接着剤で接合するに際し、（１）ポ
リオレフインチユーブの接着面にあらかじめプラズマ処
理を施し、ポリマーの接着界面に官能基を増加させ、
（２）また、接続に係わるチユーブに無可塑剤軟質ポリ
塩化ビニルを用いることによって、ポリオレフインとポ
リ塩化ビニル間の接着強力、なかんづく剥離強力を著し
く向上させる。The present invention is a medical tube and is bonded to the polyolefin inch tube and the polyvinyl chloride tube with an adhesive so that peeling does not occur at the connection portion even when operated under severe conditions such as centrifugation. In doing so, (1) plasma treatment was previously performed on the adhesive surface of the polyolefin inch uve to increase the functional groups at the adhesive interface of the polymer,
(2) Further, by using a non-plasticizer soft polyvinyl chloride in the tube for connection, the adhesive strength between the polyolefin and the polyvinyl chloride, especially the peel strength is remarkably improved.

【００１３】[0013]

【実施例】以下、本発明を実施例により具体的に説明す
る。図１は本発明の実施例を示す移行バツグへ連通管を
接続した状態の平面図である。EXAMPLES The present invention will be specifically described below with reference to examples. FIG. 1 is a plan view showing a state in which a communication pipe is connected to a transition bag showing an embodiment of the present invention.

【００１４】移行バツグの素材は可撓性の透明な滅菌し
得る、液体に溶出する可塑剤を含まない種々のプラスチ
ツク組成物であるが、ポリオレフインが好んで使用され
る。The material of the transfer bag is a flexible, transparent, sterilizable, liquid-eluting plasticizer-free plastic composition, although polyolefins are preferably used.

【００１５】本実施例におけるバツグ本体１はポリ（エ
チレンブチレン）ポリスチレンブロツク共重合体（シエ
ル化学社製クレイトンＧ−１６５０）４０重量％、ポリ
プロピレン（住友化学社製ＦＬ−６７１１Ｎ）３０重量
％、エチレンエチルアクリレート共重合体（エチルアク
リレート含量１５モル％、日本ユニカー社製ＤＰＤＪ６
１８２）３０重量％をミキサーで混合し、２００℃で溶
融押出して厚さ２５０μに成形されたシートを使用し
た。In this embodiment, the bag body 1 is composed of 40% by weight of poly (ethylene butylene) polystyrene block copolymer (Clayton G-1650 manufactured by Ciel Chemical Co., Ltd.), 30% by weight of polypropylene (FL-6711N manufactured by Sumitomo Chemical Co., Ltd.), ethylene. Ethyl acrylate copolymer (ethyl acrylate content 15 mol%, Nippon Unicar Company DPDJ6
182) A sheet formed by mixing 30% by weight with a mixer and melt-extruding at 200 ° C. to have a thickness of 250 μ was used.

【００１６】バツグ本体１は流通口４を有する。流通口
４の一部はバツグ本体１のシート間で熱融着により固定
されている。そのためには流通口４の素材はバツグ本体
１と同じか化学構造の似ていることが好ましい。The bag body 1 has a flow port 4. A part of the flow port 4 is fixed between the sheets of the bag body 1 by heat fusion. For that purpose, the material of the flow port 4 is preferably the same as the bag body 1 or similar in chemical structure.

【００１７】本実施例における流通口４はポリ（エチレ
ンブチレン）ポリスチレンブロツク共重合体（シエル化
学社製クレイトンＧ−１６５０）５４重量％、ポリプロ
ピレン（住友化学社製ＦＬ−６７１１Ｎ）２３重量％、
エチレンエチルアクリレート共重合体（エチルアクリレ
ート含量１５モル％、日本ユニカー社製ＤＰＤＪ６１８
２）２３重量％を混合した重合体を射出成形した内径
３．６ｍｍ、外径４．８ｍｍ、長さ４ｃｍのチユーブを
用いた。The flow port 4 in this embodiment is 54% by weight of poly (ethylenebutylene) polystyrene block copolymer (Clayton G-1650 manufactured by Ciel Chemical Co.), 23% by weight of polypropylene (FL-6711N manufactured by Sumitomo Chemical Co., Ltd.),
Ethylene ethyl acrylate copolymer (ethyl acrylate content 15 mol%, Nippon Unicar Co., Ltd. DPDJ618
2) A tube having an inner diameter of 3.6 mm, an outer diameter of 4.8 mm, and a length of 4 cm, which was obtained by injection-molding a polymer mixed with 23% by weight, was used.

【００１８】流通口４は、バツグ本体１に熱融着される
前に予め株式会社東芝製マイクロ波プラズマ処理機を用
いて、マイクロ波出力を１．５ｋｗ・酸素／窒素のガス
比率を９／１・真空度を１トール・処理時間を３０秒の
条件でプラズマ処理を施した。The flow port 4 has a microwave output of 1.5 kw and an oxygen / nitrogen gas ratio of 9 / using a microwave plasma processor manufactured by Toshiba Corp. before being heat-sealed to the bag body 1. Plasma treatment was performed under the conditions of 1. vacuum degree of 1 Torr and treatment time of 30 seconds.

【００１９】バツグに設けられた流通口４に無可塑剤軟
質ポリ塩化ビニル（積水化学工業株式会社製エスメデイ
カＶ）の接合管２（内径４．１ｍｍ、外径６．１ｍｍ、
長さ２ｃｍ）をエポキシ系樹脂を用いて嵌着させた。A junction pipe 2 (inner diameter 4.1 mm, outer diameter 6.1 mm) of a non-plasticizer soft polyvinyl chloride (Esmedica V manufactured by Sekisui Chemical Co., Ltd.) is attached to a flow port 4 provided in the bag.
A length of 2 cm) was fitted using an epoxy resin.

【００２０】このエポキシ系樹脂は積水化学工業株式会
社製で主剤にエスダイン３１２０Ａ、硬化剤にエスダイ
ン３１２０Ｂを用い、嵌着部接着のための硬化時間は８
０℃・３０分とした。また、接合管２と連通管３との間
はシクロヘキサノンで接着させた。This epoxy resin is manufactured by Sekisui Chemical Co., Ltd., using Esdyne 3120A as the main component and Esdyne 3120B as the curing agent, and the curing time for adhering the fitting portion is 8
It was set to 0 ° C. for 30 minutes. Further, the bonding pipe 2 and the communication pipe 3 were bonded with cyclohexanone.

【００２１】遠心分離操作による液洩れを試験するため
に、上記のようにして作製した移行バツグ５０ケを準備
した。それら各々の試料に５６０ｃｃの水を入れ、連通
管を熱でシールし、ポリエチレン袋内に収め３７７０Ｇ
×７分間の遠心分離操作を行った。液洩れを肉眼で判定
し、流通口４と接合管２の接合力を株式会社島津製作所
製のオートグラフで測定した。液洩れは見られず、接合
力は平均値で１１．５ｋｇであった。In order to test the liquid leakage due to the centrifugation operation, 50 transfer bags prepared as described above were prepared. Put 560 cc of water in each of these samples, heat seal the communication pipe, and store in a polyethylene bag 3770G
The centrifugation operation was performed for 7 minutes. The liquid leakage was visually judged, and the joining force between the flow port 4 and the joint pipe 2 was measured by an autograph manufactured by Shimadzu Corporation. No liquid leakage was observed, and the joining force was 11.5 kg on average.

【００２２】比較例１として、流通口４にプラズマ処理
を施さないで、接合管２に可塑剤入りポリ塩化ビニルを
用い、他は実施例と同じものを作り、実施例と同じ評価
をした。液洩れは５０ケのうち３８ケ見られ、接合力は
平均値で７．１ｋｇであった。比較例２として、流通口
４にプラズマ処理を施さないで、接合管２に無可塑剤軟
質ポリ塩化ビニルを用い、他は実施例と同じものを作
り、実施例と同じ評価をした。液洩れは５０ケのうち１
０ケ見られ、接合力は平均値で８．９ｋｇであった。比
較例３として、流通口４に実施例と同じプラズマ処理を
施し、接合管２に可塑剤入りポリ塩化ビニルを用い、他
は実施例と同じものを作り、実施例と同じ評価をした。
液洩れは５０ケのうち２ケ見られ、接合力は平均値で１
０．２ｋｇであった。As Comparative Example 1, the same process as in the other examples was prepared by using polyvinyl chloride containing a plasticizer in the joining pipe 2 without performing plasma treatment on the flow port 4, and the same evaluation as the examples was made. 38 of the 50 liquid leaks were seen, and the average bonding force was 7.1 kg. As Comparative Example 2, the same process as in the other examples was made by using the non-plasticizer soft polyvinyl chloride for the joining pipe 2 without performing the plasma treatment on the flow port 4, and the same evaluation as the example was performed. 1 out of 50 leaks
Zero of them were seen, and the bonding strength was 8.9 kg on average. As Comparative Example 3, the same plasma treatment as that of the example was applied to the flow port 4, polyvinyl chloride containing a plasticizer was used for the joining tube 2, and the same thing as the example was made except for that, and the same evaluation as the example was made.
Two out of 50 leaks were seen, and the joining force was 1 on average.
It was 0.2 kg.

【００２３】[0023]

【発明の効果】本発明は，医療用チユーブであってポリ
オレフインチユーブとポリ塩化ビニルチユーブを接着剤
で接合するに際し、ポリオレフインチユーブの接着面に
あらかじめプラズマ処理を施し、接続に係わるチユーブ
だけに無可塑剤軟質ポリ塩化ビニルを用いたものであ
る。従って、本発明によればポリオレフインチユーブと
ポリ塩化ビニルチユーブ間の接合力が大となる。例えば
マルチバツグなどの医療用チユーブに用いると本発明の
効果を奏するものである。INDUSTRIAL APPLICABILITY The present invention is a medical tube, in which the polyolefin surface tube and the polyvinyl chloride tube are bonded with an adhesive, the adhesive surface of the polyolefin tube is subjected to a plasma treatment in advance, and only the connection-related tube is unplasticized. The softening agent is polyvinyl chloride. Therefore, according to the present invention, the bonding force between the polyolefin inch tube and the polyvinyl chloride tube becomes large. For example, when used in a medical tube such as multi-bag, the effect of the present invention is exhibited.

【図面の簡単な説明】[Brief description of drawings]

【図１】本発明の実施例を示す移行バツグへ連通管を接
続した状態の平面図である。FIG. 1 is a plan view showing a state in which a communication pipe is connected to a transition bag according to an embodiment of the present invention.

【符号の説明】[Explanation of symbols]

１ バツグ本体 ２ 接合管 ３ 連通管 ４ 流通口 1 Bag main body 2 Joined pipe 3 Communication pipe 4 Flow port

Claims (1)

【特許請求の範囲】[Claims] 【請求項１】 ポリオレフインチユーブとポリ塩化ビニ
ルチユーブを接着剤で接合するに際し、ポリオレフイン
チユーブの接着面にあらかじめプラズマ処理をなし、か
つ、ポリ塩化ビニルチユーブには無可塑剤軟質ポリ塩化
ビニルを使用することを特徴とする医療用チユーブの接
続方法。1. When the polyolefin inch tube and the polyvinyl chloride tube are bonded with an adhesive, the bonding surface of the polyolefin inch tube is previously subjected to plasma treatment, and the polyvinyl chloride tube is made of a non-plasticizer soft polyvinyl chloride. A method for connecting a medical tube, which is characterized in that
JP03223465A 1991-08-08 1991-08-08 How to connect a medical tube Expired - Fee Related JP3092674B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP03223465A JP3092674B2 (en) 1991-08-08 1991-08-08 How to connect a medical tube

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP03223465A JP3092674B2 (en) 1991-08-08 1991-08-08 How to connect a medical tube

Publications (2)

Publication Number Publication Date
JPH0542203A true JPH0542203A (en) 1993-02-23
JP3092674B2 JP3092674B2 (en) 2000-09-25

Family

ID=16798577

Family Applications (1)

Application Number Title Priority Date Filing Date
JP03223465A Expired - Fee Related JP3092674B2 (en) 1991-08-08 1991-08-08 How to connect a medical tube

Country Status (1)

Country Link
JP (1) JP3092674B2 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1697745A1 (en) * 2003-12-18 2006-09-06 DIGITAL BIO TECHNOLOGY Seoul National University Institute of Advance Method for bonding plastic micro chip
WO2021003244A1 (en) * 2019-07-01 2021-01-07 Saint-Gobain Performance Plastics Corporation Profile connection
US11878476B2 (en) 2020-06-19 2024-01-23 Saint-Gobain Performance Plastics Corporation Composite article and method of forming a composite article

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1697745A1 (en) * 2003-12-18 2006-09-06 DIGITAL BIO TECHNOLOGY Seoul National University Institute of Advance Method for bonding plastic micro chip
EP1697745A4 (en) * 2003-12-18 2009-01-21 Digital Bio Technology Seoul N Method for bonding plastic micro chip
US8900531B2 (en) 2003-12-18 2014-12-02 Nanoentek Inc. Method for bonding plastic micro chip
WO2021003244A1 (en) * 2019-07-01 2021-01-07 Saint-Gobain Performance Plastics Corporation Profile connection
CN114007845A (en) * 2019-07-01 2022-02-01 美国圣戈班性能塑料公司 Section bar connecting piece
CN114007850A (en) * 2019-07-01 2022-02-01 美国圣戈班性能塑料公司 Section bar connecting piece
US11904552B2 (en) 2019-07-01 2024-02-20 Saint-Gobain Performance Plastics Corporation Profile connection
US11878476B2 (en) 2020-06-19 2024-01-23 Saint-Gobain Performance Plastics Corporation Composite article and method of forming a composite article

Also Published As

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