JPH0541707Y2 - - Google Patents

Info

Publication number

JPH0541707Y2

JPH0541707Y2 JP2169191U JP2169191U JPH0541707Y2 JP H0541707 Y2 JPH0541707 Y2 JP H0541707Y2 JP 2169191 U JP2169191 U JP 2169191U JP 2169191 U JP2169191 U JP 2169191U JP H0541707 Y2 JPH0541707 Y2 JP H0541707Y2

Authority

JP

Japan

Prior art keywords

tube

drug

present

powdered

ulcer

Prior art date

1991-04-04

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Expired - Lifetime

Links

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• 239000003814 drug Substances 0.000 claims description 53
• 229940079593 drug Drugs 0.000 claims description 37
• 238000002347 injection Methods 0.000 claims description 11
• 239000007924 injection Substances 0.000 claims description 11
• 239000000843 powder Substances 0.000 claims description 11
• 208000025865 Ulcer Diseases 0.000 description 12
• 231100000397 ulcer Toxicity 0.000 description 12
• 230000003902 lesion Effects 0.000 description 9
• 239000007789 gas Substances 0.000 description 8
• IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 description 7
• 238000000034 method Methods 0.000 description 7
• 235000010413 sodium alginate Nutrition 0.000 description 7
• 229940005550 sodium alginate Drugs 0.000 description 7
• 239000000661 sodium alginate Substances 0.000 description 7
• 230000000740 bleeding effect Effects 0.000 description 5
• 238000010586 diagram Methods 0.000 description 4
• 210000001035 gastrointestinal tract Anatomy 0.000 description 4
• 239000007788 liquid Substances 0.000 description 4
• 239000012530 fluid Substances 0.000 description 3
• CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
• 208000008469 Peptic Ulcer Diseases 0.000 description 2
• 208000007107 Stomach Ulcer Diseases 0.000 description 2
• 239000000443 aerosol Substances 0.000 description 2
• 239000003699 antiulcer agent Substances 0.000 description 2
• 239000007864 aqueous solution Substances 0.000 description 2
• 201000010099 disease Diseases 0.000 description 2
• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
• 208000000718 duodenal ulcer Diseases 0.000 description 2
• 238000005516 engineering process Methods 0.000 description 2
• 210000004798 organs belonging to the digestive system Anatomy 0.000 description 2
• 239000007921 spray Substances 0.000 description 2
• 210000002784 stomach Anatomy 0.000 description 2
• 230000001225 therapeutic effect Effects 0.000 description 2
• IVVHAAOJLULJLK-YDXSIYMFSA-E Aceglutamide aluminum Chemical compound [OH-].[OH-].[OH-].[OH-].[Al+3].[Al+3].[Al+3].CC(=O)N[C@H](C([O-])=O)CCC(N)=O.CC(=O)N[C@H](C([O-])=O)CCC(N)=O.CC(=O)N[C@H](C([O-])=O)CCC(N)=O.CC(=O)N[C@H](C([O-])=O)CCC(N)=O.CC(=O)N[C@H](C([O-])=O)CCC(N)=O IVVHAAOJLULJLK-YDXSIYMFSA-E 0.000 description 1
• IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 1
• 229920000742 Cotton Polymers 0.000 description 1
• MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 description 1
• 206010027146 Melanoderma Diseases 0.000 description 1
• 241001465754 Metazoa Species 0.000 description 1
• 229930192392 Mitomycin Natural products 0.000 description 1
• NWIBSHFKIJFRCO-WUDYKRTCSA-N Mytomycin Chemical compound C1N2C(C(C(C)=C(N)C3=O)=O)=C3[C@@H](COC(N)=O)[C@@]2(OC)[C@@H]2[C@H]1N2 NWIBSHFKIJFRCO-WUDYKRTCSA-N 0.000 description 1
• 206010028980 Neoplasm Diseases 0.000 description 1
• 208000005718 Stomach Neoplasms Diseases 0.000 description 1
• 238000010521 absorption reaction Methods 0.000 description 1
• 229960002627 aceglutamide aluminum Drugs 0.000 description 1
• 239000002246 antineoplastic agent Substances 0.000 description 1
• 239000008280 blood Substances 0.000 description 1
• 210000004369 blood Anatomy 0.000 description 1
• 238000009534 blood test Methods 0.000 description 1
• 239000001569 carbon dioxide Substances 0.000 description 1
• 229910002092 carbon dioxide Inorganic materials 0.000 description 1
• FHRSHSOEWXUORL-HDJSIYSDSA-N cetraxate Chemical compound C1C[C@@H](C[NH3+])CC[C@@H]1C(=O)OC1=CC=C(CCC([O-])=O)C=C1 FHRSHSOEWXUORL-HDJSIYSDSA-N 0.000 description 1
• 229950009533 cetraxate Drugs 0.000 description 1
• 238000002512 chemotherapy Methods 0.000 description 1
• CCGSUNCLSOWKJO-UHFFFAOYSA-N cimetidine Chemical compound N#CNC(=N/C)\NCCSCC1=NC=N[C]1C CCGSUNCLSOWKJO-UHFFFAOYSA-N 0.000 description 1
• 229960002908 cimetidine hydrochloride Drugs 0.000 description 1
• 230000007547 defect Effects 0.000 description 1
• 229910001873 dinitrogen Inorganic materials 0.000 description 1
• 229910001882 dioxygen Inorganic materials 0.000 description 1
• 230000002183 duodenal effect Effects 0.000 description 1
• 210000001198 duodenum Anatomy 0.000 description 1
• 230000000694 effects Effects 0.000 description 1
• 230000002550 fecal effect Effects 0.000 description 1
• 239000000835 fiber Substances 0.000 description 1
• NBVXSUQYWXRMNV-UHFFFAOYSA-N fluoromethane Chemical compound FC NBVXSUQYWXRMNV-UHFFFAOYSA-N 0.000 description 1
• 206010017758 gastric cancer Diseases 0.000 description 1
• 230000002496 gastric effect Effects 0.000 description 1
• 201000005917 gastric ulcer Diseases 0.000 description 1
• 230000007721 medicinal effect Effects 0.000 description 1
• 230000002503 metabolic effect Effects 0.000 description 1
• 229960004857 mitomycin Drugs 0.000 description 1
• 210000004877 mucosa Anatomy 0.000 description 1
• 231100000957 no side effect Toxicity 0.000 description 1
• 210000000056 organ Anatomy 0.000 description 1
• 230000035699 permeability Effects 0.000 description 1
• 231100000241 scar Toxicity 0.000 description 1
• 238000007789 sealing Methods 0.000 description 1
• 239000000243 solution Substances 0.000 description 1
• 238000005507 spraying Methods 0.000 description 1
• 201000011549 stomach cancer Diseases 0.000 description 1
• -1 suralfate Chemical compound 0.000 description 1
• 229920003002 synthetic resin Polymers 0.000 description 1
• 239000000057 synthetic resin Substances 0.000 description 1
• WFWLQNSHRPWKFK-ZCFIWIBFSA-N tegafur Chemical compound O=C1NC(=O)C(F)=CN1[C@@H]1OCCC1 WFWLQNSHRPWKFK-ZCFIWIBFSA-N 0.000 description 1
• 229960001674 tegafur Drugs 0.000 description 1
• 238000002560 therapeutic procedure Methods 0.000 description 1
• 210000003813 thumb Anatomy 0.000 description 1
• 210000001519 tissue Anatomy 0.000 description 1
• 238000001665 trituration Methods 0.000 description 1
• 235000013311 vegetables Nutrition 0.000 description 1