JPH05285213A - Method of treating surface of implantation material - Google Patents
Method of treating surface of implantation materialInfo
- Publication number
- JPH05285213A JPH05285213A JP4014047A JP1404792A JPH05285213A JP H05285213 A JPH05285213 A JP H05285213A JP 4014047 A JP4014047 A JP 4014047A JP 1404792 A JP1404792 A JP 1404792A JP H05285213 A JPH05285213 A JP H05285213A
- Authority
- JP
- Japan
- Prior art keywords
- implant material
- implantation material
- aqueous solution
- treatment
- apatite
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
Description
【０００１】[0001]
【産業上の利用分野】本発明は人工骨、人工歯根等のイ
ンプラント材の表面処理に関する。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to surface treatment of implant materials such as artificial bone and artificial tooth root.
【０００２】[0002]
【従来の技術】インプラントとしては金属、セラミック
ス、有機高分子材料が利用されているが、一般に異物を
生体内に埋入した場合、材料の周囲の組織は異物に対し
てある種の生体反応を起こすことが知られている。この
場合、インプラント材が比較的生体組織に類似している
場合は同化吸収されるが、有害な金属等が埋入された場
合は、周囲組織はこの異物を速やかに離隔しようとして
繊維組織で包み込み、生体外に速やかに排出しようとす
る。一方、骨内埋込み材料では、アパタイトなどはほぼ
同化吸収を受けるのに対し、金属の場合は骨組織との直
接結合かもしくはきわめて薄い膜で覆われる。又関節、
骨、歯根等の生体硬組織用の材料には更に静的力学的強
度、耐疲労性などの動的強度、弾性率などについても周
囲の骨組織と調和する特性を必要とする。2. Description of the Related Art Metals, ceramics, and organic polymer materials are used as implants. Generally, when a foreign body is implanted in a living body, the tissue around the material causes some kind of biological reaction to the foreign body. It is known to wake up. In this case, if the implant material is relatively similar to living tissue, it will be assimilated and absorbed, but if harmful metal etc. is embedded, the surrounding tissue will wrap it in the fibrous tissue in order to quickly separate this foreign substance. , Try to expel it out of the body promptly. On the other hand, in the intraosseous implant material, apatite and the like are almost assimilated and absorbed, whereas in the case of metal, they are directly bonded to bone tissue or covered with an extremely thin film. Another joint,
Materials for living body hard tissues such as bones and tooth roots are required to have characteristics such as static mechanical strength, dynamic strength such as fatigue resistance, elastic modulus, etc., which are in harmony with surrounding bone tissues.
【０００３】このような観点から従来比較的生体になじ
み易い金属材料としてＴｉ、Ｔｉ合金、Ｃｒ合金、Ｎｉ
合金、ＴａＮｂ、貴金属等が利用されている。このＴｉ
等は元来不銹材であると言われてはいるが、長期間体内
にとどまった場合は必ずしも不透であるとはいえない点
がある。即ち、体液と接する表面には微弱ながら腐食が
生じ、これが材料強度の低下や摺動部の摩耗を促進す
る。又金属の腐食の際に金属イオンが周囲の生体組織へ
移行する現象が見られるなどの弊害がある。From such a viewpoint, Ti, Ti alloys, Cr alloys, and Ni have hitherto been used as metal materials which are relatively easily adapted to the living body.
Alloys, TaNb, precious metals, etc. are used. This Ti
Originally, it is said that it is a rustless material, but if it stays in the body for a long time, it is not necessarily impermeable. That is, the surface in contact with body fluid is slightly corroded, which accelerates the deterioration of the material strength and the wear of the sliding portion. In addition, there is an adverse effect such as the phenomenon that metal ions migrate to surrounding living tissues when the metal is corroded.
【０００４】このため、金属材料の表面に生体に同化吸
収し易い前記アパタイトを被覆処理する技術が既に提案
されている。即ち、本発明者等が既に提案した処理方法
は、燐酸とカルシウムの混合水溶液中にインプラント材
を挿入して、該インプラント材を陰極として前記水溶液
との間に通電（放電を含む）して、インプラント材の表
面に燐酸カルシウムを析出させる方法、即ちＣａ10（Ｐ
Ｏ4 ）6 （ＯＨ）2 を析出させる方法である。しかしな
がら、この方法による場合、燐酸カルシウムの析出層内
にインプラント材の成形加工時に生じた工具材料等から
離脱、付着した不純物が残留しており、この不純物がイ
ンプラントの生体への植込み時に種々の障害を引き起す
欠点があった。Therefore, a technique has already been proposed for coating the surface of a metal material with the apatite that is easily assimilated and absorbed by the living body. That is, the treatment method that the present inventors have already proposed is to insert an implant material into a mixed aqueous solution of phosphoric acid and calcium, and apply current (including discharge) between the implant material as a cathode and the aqueous solution, A method of depositing calcium phosphate on the surface of the implant material, that is, Ca 10 (P
This is a method of precipitating O 4 ) 6 (OH) 2 . However, in the case of this method, impurities that are detached from and adhered to the tool material generated during the molding process of the implant material remain in the calcium phosphate precipitation layer, and these impurities cause various obstacles when the implant is implanted in the living body. There was a drawback that caused.
【０００５】[0005]
【発明が解決しようとする課題】本発明は上記の従来の
欠点を除去し、安定した植込みができる生体親和性の高
いインプラントの表面処理方法を提供することを目的と
する。SUMMARY OF THE INVENTION It is an object of the present invention to provide a method for treating the surface of an implant with high biocompatibility, which enables stable implantation by eliminating the above-mentioned conventional drawbacks.
【０００６】[0006]
【課題を解決するための手段】本発明は、燐酸塩とカル
シウム化合物の混合水溶液中にインプラント材を挿入
し、該インプラント材を陰極として上記混合水溶液との
間に通電（放電を含む）を行なって、インプラント材表
面にアパタイトを析出させる表面処理方法に於いて、上
記通電によるアパタイト析出処理の前処理として、上記
インプラント材を弗化物水溶液で洗浄しその表面に弗化
物を付着させる処理を行なうことを特徴とするインプラ
ント材の表面処理方法を提供する。According to the present invention, an implant material is inserted into a mixed aqueous solution of a phosphate and a calcium compound, and an electric current (including discharge) is performed between the implant material and the mixed aqueous solution as a cathode. In the surface treatment method of depositing apatite on the surface of the implant material, as a pretreatment for the apatite deposition treatment by the above-mentioned energization, a treatment of washing the implant material with an aqueous solution of fluoride and depositing fluoride on the surface is performed. There is provided a surface treatment method for an implant material.
【０００７】[0007]
【作用】本発明は、上記の如く、始めにインプラント材
を弗化物水溶液で洗浄する表面処理を行なってから、ア
パタイトを析出する表面処理を行なうようにしたから、
インプラント材の表面に不純物が残留しない生体親和性
の高いアパタイトを析出させることができ、しかも析出
アパタイトとしては洗浄時に付着した弗素を取り込んだ
弗素化アパタイトＣａ10（ＰＯ4 ）6 Ｆ2x（Ｏ
Ｈ）2-2x、やＣａ5 （ＰＯ 4 ）3 Ｆ0.2-0.5 （ＯＨ）
0.5-0.8 を析出させることができる。The function of the present invention is, as described above, the implant material.
Surface treatment with a fluoride aqueous solution, and then
Since the surface treatment to deposit the patite is performed,
Biocompatibility with no impurities remaining on the surface of the implant material
Can deposit apatite with high
As apatite, the fluorine attached during cleaning was taken in.
Fluorinated apatite CaTen(POFour)6F2x(O
H)2-2x, And CaFive(PO Four)3F0.2-0.5(OH)
0.5-0.8Can be deposited.
【０００８】[0008]
【実施例】以下、図面に示した一実施例により本発明を
説明する。図１は、本発明に係るインプラント材の表面
処理を行なう際の洗浄工程説明図で、槽１内の底部に超
音波振動子２が挿入され、槽１内には洗浄液３が満たさ
れる。この洗浄液には弗化物水溶液、例えばＨＦの５％
水溶液が用いられ、この洗浄液３中にインプラント材４
を挿入して洗浄する。洗浄液３は振動子２によって超音
波振動が付与され、この超音波振動液３によりインプラ
ント材４の表面浄化処理が行なわれる。ＨＦ水溶液は腐
食性があり、インプラント材４の表面に付着する銅等を
微小量づつ溶解し、更に表面に付着した他の金属等不純
物を洗浄除去する。洗浄されたインプラント材４はコン
ベアベルト５により取り出すが、この洗浄処理されたイ
ンプラント材４の表面には洗浄液の弗化物が付着した状
態となる。DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS The present invention will be described below with reference to an embodiment shown in the drawings. FIG. 1 is an explanatory view of a cleaning process when the surface treatment of an implant material according to the present invention is performed. An ultrasonic transducer 2 is inserted into the bottom of a tank 1 and the tank 1 is filled with a cleaning liquid 3. This cleaning solution contains an aqueous solution of fluoride, for example, 5% of HF.
An aqueous solution is used, and the implant material 4 is added to the cleaning solution 3.
Insert and wash. Ultrasonic vibration is applied to the cleaning liquid 3 by the vibrator 2, and the surface cleaning treatment of the implant material 4 is performed by the ultrasonic vibration liquid 3. The HF aqueous solution is corrosive and dissolves minute amounts of copper and the like adhering to the surface of the implant material 4, and further removes impurities such as other metals adhering to the surface by washing. The cleaned implant material 4 is taken out by the conveyor belt 5, and the fluoride of the cleaning liquid is attached to the surface of the cleaned implant material 4.
【０００９】図２は、上記洗浄工程に続いてインプラン
ト材の表面にアパタイトを析出せしめる処理を行なう工
程図で、図において、６は処理容器で、内部に処理混合
液７を貯蔵する。４は液中に挿入したインプラント材、
８は処理混合液７に通電するために容器６の底に浸漬し
た通電電極、９はインプラント材４と電極８との間に通
電する電源装置であって、通常パルス電源が用いられ、
又これに直流、交流、高周波等を重畳したものが利用さ
れる。FIG. 2 is a process chart of performing a treatment for precipitating apatite on the surface of the implant material after the cleaning step. In the figure, 6 is a treatment container in which the treatment mixture 7 is stored. 4 is an implant material inserted in the liquid,
Reference numeral 8 is a current-carrying electrode immersed in the bottom of the container 6 for supplying current to the treatment mixture 7, and 9 is a power supply device for supplying current between the implant material 4 and the electrode 8, which is usually a pulse power supply,
Moreover, what superposed DC, AC, and a high frequency on this is used.
【００１０】混合水溶液７を構成する燐酸塩には次のよ
うなものが利用される。 （１）無機燐酸塩 燐酸ソーダ、ポリメタ燐酸、燐酸カルシウム、その他 （２）燐酸エルテル ＤＭＰ、ＴＭＰ、ＴＢＰ、ＴＥＰ、その他 （３）ＡＴＰ、その他のヌクレオチド及び核酸類 （４）その他の燐酸有機化合物 燐酸セルローズ、燐酸澱粉、その他The following are used as the phosphate constituting the mixed aqueous solution 7. (1) Inorganic Phosphate Sodium Phosphate, Polymetaphosphoric Acid, Calcium Phosphate, Others (2) Ertel Phosphate DMP, TMP, TBP, TEP, Others (3) ATP, Other Nucleotides and Nucleic Acids (4) Other Phosphate Organic Compounds Phosphate Cellulose, starch phosphate, etc.
【００１１】又、混合水溶液７を構成するカルシウム化
合物としては次のようなものが用いられる。 （１）有機酸カルシウム塩 酢酸、酪酸、吉草酸、乳酸、グルコン酸、酒石酸、クエ
ン酸、アジピン酸等のカルシウム塩、その他 （２）キレートのカルシウム塩 ＥＤＴＡ、ＮＴＡ、ＨＥＤＴＥ等のカルシウム塩、その
他 （３）イオノフォアカルシウム塩 シクロペンタジェニル、クラウンエーテル、クリプタン
ト等のカルシウム塩、その他、 （４）無機化合物 ＣａＣｌ2 、燐酸カルシウム、酸化カルシウム、その
他、 又、アルコキシド−（Ｃａ）＋アルコール−燐酸混合液
を用いることもできる。Further, as the calcium compound constituting the mixed aqueous solution 7, the following compounds are used. (1) Calcium salt of organic acid Acetic acid, butyric acid, valeric acid, lactic acid, gluconic acid, tartaric acid, citric acid, adipic acid, etc., calcium salt, etc. (2) Calcium salt of chelate: EDTA, NTA, HEDTE, etc. calcium salt, etc. (3) Calcium salt of ionophore calcium, cyclopentagenyl, crown ether, calcium salt such as cryptant, and others (4) Inorganic compound CaCl 2 , calcium phosphate, calcium oxide, others, and alkoxide- (Ca) + alcohol-phosphate mixture A liquid can also be used.
【００１２】この混合水溶液７中にインプラント材４を
挿入した状態で、インプラント材４を陰極として電源９
から通電すると、電解作用により酸素、水素ガス、水蒸
気等の多量のガス10が発生し、これが陰極側のインプラ
ント材４の表面に付着し、インプラント材を覆うように
なる。この電解発生ガスのために等価的には通電回路中
に直列抵抗が入ったことと同様になり、この抵抗はガス
発生量に比例して間隙抵抗値が増大する。インプラント
材の表面がこのガスで覆われた状態で電解電流を更に増
大して限界電流を越えると放電が発生するようになる。
即ち、電流を増大すると発生ガスも増加し、抵抗値がガ
スの発生量に比例して増大し、ジュール熱が発生し、加
熱が始まる。これによりインプラント材４の周辺の液の
温度が次第に上昇し、水蒸気と電解ガスなどのために発
生ガス部分で放電が発生するようになる。液７とインプ
ラント材４間で放電が発生するようになれば増々温度が
上昇し、それにつれて水蒸気とガスの発生量が増加して
インプラント材４の表面全体を包んだ状態になり、抵抗
値が更に増大して急速に加熱、昇温するようになる。イ
ンプラント材周辺の液が 100℃近くになると、水蒸気と
電解ガスのために発生ガス部分で放電が盛んに起り、こ
の液７とインプラント材４の表面間で放電状態が形成さ
れると、ますます加熱速度が速くなり、1,000 〜2,000
℃程度まで容易に加熱することができる。この放電の加
熱作用、衝撃効果、放電電解等によって活性化されたイ
ンプラント材４の表面には、洗浄工程で付着処理された
弗化物と混合水溶液７の成分の化学反応によって、弗素
を取り込んだ弗素化アパタイトＣａ10( ＰＯ4 )6Ｆ
2x（ＯＨ) 2-2xやＣａ5 （ＰＯ4 ）3 Ｆ0.2-0.5 （Ｏ
Ｈ）0. 5-0.8 が析出する。なお式中のｘは弗素の取り込
み量による弗素化度を示す。With the implant material 4 inserted in the mixed aqueous solution 7, the implant material 4 is used as a cathode and a power source 9 is used.
When a current is applied from the inside, a large amount of gas 10 such as oxygen, hydrogen gas and water vapor is generated due to the electrolytic action, and this adheres to the surface of the implant material 4 on the cathode side and covers the implant material. This electrolytically generated gas is equivalently equivalent to the inclusion of a series resistance in the energizing circuit, and this resistance increases the gap resistance value in proportion to the gas generation amount. When the surface of the implant material is covered with this gas and the electrolytic current is further increased to exceed the limit current, discharge will occur.
That is, when the current is increased, the amount of generated gas also increases, the resistance value increases in proportion to the amount of gas generated, Joule heat is generated, and heating starts. As a result, the temperature of the liquid around the implant material 4 gradually rises, and electric discharge is generated in the generated gas portion due to water vapor and electrolytic gas. If an electric discharge is generated between the liquid 7 and the implant material 4, the temperature rises more and more, the amount of water vapor and gas generated increases accordingly, and the entire surface of the implant material 4 is wrapped, resulting in a resistance value. Further increase, heating and temperature increase rapidly. When the temperature of the liquid around the implant material approaches 100 ° C, electric discharge is actively generated in the generated gas due to steam and electrolysis gas, and a discharge state is formed between the surface of this liquid 7 and the surface of the implant material 4. The heating rate is faster, 1,000-2,000
It can be easily heated to about ℃. On the surface of the implant material 4 activated by the heating effect of this discharge, the impact effect, the discharge electrolysis, etc., fluorine incorporated with fluorine by the chemical reaction between the fluoride adhered in the cleaning step and the component of the mixed aqueous solution 7. Apatite Ca 10 (PO 4 ) 6 F
2x (OH) 2-2x and Ca 5 (PO 4 ) 3 F 0.2-0.5 (O
H) 0. 5-0.8 is precipitated. In the formula, x represents the degree of fluorination depending on the amount of fluorine taken up.
【００１３】この析出被膜はインプラント材４の温度上
昇によって更に焼付等の熱処理され、強く溶着して基材
との密着性を高め、強固なアパタイト膜が形成される。
又このアパタイト膜は基材に対して厚さ数μｍから10数
μｍの均一な被覆が容易に生成するので、インプラント
表面処理として有効に利用することができる。又この表
面処理後に熱処理を施すことが推奨され、これによりイ
ンプラント表面に強く焼き付いた強固なアパタイト被膜
を形成できる。This deposited film is further heat-treated such as baking by increasing the temperature of the implant material 4 and strongly welded to enhance the adhesion to the base material to form a strong apatite film.
Further, since this apatite film easily forms a uniform coating having a thickness of several μm to several tens of μm on the substrate, it can be effectively used as a surface treatment for implants. Further, it is recommended that a heat treatment is performed after this surface treatment, whereby a strong apatite coating strongly baked on the implant surface can be formed.
【００１４】次に実験例を説明すると、先ずインプラン
ト材（Ｔｉ材）を５％のＨＦ水溶液中で超音波洗浄す
る。洗浄により表面の付着不純物を除去すると共に、表
面にＨＦ水が付着したインプラント材を、クエン酸５％
と燐酸カルシウム20％の超飽和混合水溶液に更に燐酸を
体積比で1.5 ％添加した混合水溶液中に挿入し、インプ
ラント材を陰極として電解液中放電を行なって表面処理
を行なった。通電条件は平均電圧60Ｖ、平均電流１Ａで
１分間の処理によりインプラント材（Ｔｉ材）の表面に
厚さ約16μｍ程度のアパタイト膜を生成した。生成膜中
の析出はＣａ10（ＰＯ4)6 Ｆ2 （ＯＨ）が約89％であっ
た。Explaining an experimental example, first, an implant material (Ti material) is ultrasonically cleaned in a 5% HF aqueous solution. Impurities on the surface are removed by washing, and the implant material with HF water adhered to the surface is treated with 5% citric acid.
Then, the solution was inserted into a super-saturated mixed solution of 20% calcium phosphate and 1.5% by volume of phosphoric acid, and the surface treatment was performed by discharging in an electrolyte solution using the implant material as a cathode. The energization conditions were an average voltage of 60 V and an average current of 1 A for 1 minute to form an apatite film having a thickness of about 16 μm on the surface of the implant material (Ti material). Precipitation in the product film Ca 10 (PO 4) 6 F 2 (OH) was about 89%.
【００１５】この成形被膜は約700 ℃の熱処理によりガ
ラス質化することができ、線膨張係数が約８〜10×10-6
℃程度であって、インプラント材として極めて有効であ
った。即ちこの生成されたアパタイトは基材に強く密着
しており、生体親和性が高く、この薄膜形成によってＴ
ｉインプラント材を安全に骨内に埋め込むことができ
る。又、Ｔｉインプラント材の表面はアパタイト形成処
理前にＨＦ水で充分に洗浄されてインプラント加工時等
に付着した不純物が洗浄除去され、純なＴｉ材表面に生
体親和性の高いアパタイト薄膜が形成処理されたもので
あるから、これによって極めて安定な埋込み状態が達成
できる。This molded coating can be vitrified by heat treatment at about 700 ° C. and has a linear expansion coefficient of about 8-10 × 10 -6.
The temperature was about 0 ° C, which was extremely effective as an implant material. That is, the generated apatite is strongly adhered to the base material and has high biocompatibility, and T film is formed by forming this thin film
The i-implant material can be safely embedded in the bone. Also, the surface of the Ti implant material is thoroughly washed with HF water before the apatite formation treatment to remove impurities adhering during the implant processing etc., and a pure biocompatible apatite thin film is formed on the surface of the Ti implant material. As a result, an extremely stable embedded state can be achieved.
【００１６】又、析出するアパタイトは洗浄時に付着し
た弗化物をアパタイト中に取り込んだ弗素化アパタイト
であり、アパタイト中に含まれるＦ- の結晶成長促進作
用及び溶解抑制作用により、極めて安定した植込みがで
きる。なお洗浄剤にはＨＦ＋ＨＮＯ3 、ＨＦ＋ＥＰＷ、
ＨＦ＋ＫＯＨ等を用いることができ、洗浄液を攪拌流動
させながら洗浄処理を行なうことも推奨される。The precipitated apatite is a fluorinated apatite in which the fluoride adhering at the time of cleaning is taken into the apatite. Due to the crystal growth promoting action and the dissolution inhibiting action of F − contained in the apatite, extremely stable implantation can be achieved. it can. The cleaning agent is HF + HNO 3 , HF + EPW,
HF + KOH or the like can be used, and it is also recommended to perform the cleaning treatment while stirring and flowing the cleaning liquid.
【００１７】上記の如くして作製したインプラント材
を、 600メッシュに研磨した豚の象牙質内に埋入し、そ
の接着試験を行なったところ、７日で 70kgf／cm2 とな
り実用的に優れた効果が得られ、弗素化アパタイト被膜
の強度は 10.2kgf／mm2 であった。場合によっては更に
ＣａＦ2 を添加することも有効である。The implant material produced as described above was embedded in porcine dentin polished to 600 mesh, and the adhesion test was conducted. As a result, it was 70 kgf / cm 2 in 7 days, which was practically excellent. The effect was obtained, and the strength of the fluorinated apatite coating was 10.2 kgf / mm 2 . It is also effective to add CaF 2 in some cases.
【００１８】[0018]
【発明の効果】以上のように、本発明はインプラント材
の表面処理に当り、所要の成形加工したインプラント材
を始めに弗化物水溶液で洗浄し、表面の不純物を除去す
ると共に、洗浄液に含まれる弗か物をインプラント材の
表面に付着させる処理を施し、次いで燐酸塩とカルシウ
ム化合物の混合水溶液中で、インプラント材を陰極とし
て上記混合水溶液との間に通電（放電を含む）を行なっ
て、インプラント材の表面に弗素を取り込んだ弗素化ア
パタイトを析出させる表面処理を行なうようにしたか
ら、不純物が残留しないで極めて安全に骨内に埋込むこ
とができ、骨内インプラントとして生体親和性の高い良
好なアパタイト被膜が形成され、これにより、骨内に埋
入されたインプラント材は安定した生物学的同化吸収作
用を受けると同時にその部位に新生骨が形成促進され、
骨と一体的に強固に結合するようになる。又、析出する
アパタイトは洗浄時に付着した弗素をアパタイト中に取
り込んだ弗素化アパタイトであり、アパタイト中に含ま
れるＦ- の結晶成長作用及び溶解抑制作用によって極め
て安定した植込みが可能となる。As described above, according to the present invention, when the surface treatment of the implant material is performed, the required implant material is first washed with the aqueous solution of fluoride to remove the impurities on the surface and is contained in the washing liquid. Implanting the implant material is performed by applying a treatment for adhering fluoride to the surface of the implant material, and then applying electricity (including discharge) between the mixed solution of phosphate and calcium compound and using the implant material as a cathode. Since the surface treatment of depositing fluorinated apatite containing fluorine is performed on the surface of the material, it can be embedded in bone very safely without impurities remaining, and has a high biocompatibility as an intraosseous implant. Apatite coating is formed, which allows the implant material implanted in the bone to undergo a stable biological assimilation and absorption at the same time. Site new bone is formed promoted to the,
It becomes a strong bond with the bone. Further, the precipitated apatite is a fluorinated apatite in which fluorine adhering at the time of cleaning is taken into the apatite, and extremely stable implantation is possible due to the crystal growth action and the dissolution inhibiting action of F − contained in the apatite.
【図１】本発明の前処理洗浄工程の一実施例図である。FIG. 1 is an example of a pretreatment cleaning step of the present invention.
【図２】本発明のアパタイト被覆処理工程の一実施例図
である。FIG. 2 is an example of an apatite coating treatment step of the present invention.
１ 洗浄処理槽 ２ 振動子 ３ 洗浄液 ４ インプラント ６ 被覆処理槽 ７ 処理混合液 ８ 通電電極 ９ 通電電源 10 電解発生ガス 1 Cleaning Treatment Tank 2 Transducer 3 Cleaning Solution 4 Implant 6 Coating Treatment Tank 7 Treatment Mixture 8 Energizing Electrode 9 Energizing Power Supply 10 Electrolysis Generation Gas
Claims (2)
中にインプラント材を挿入し、該インプラント材を陰極
として上記混合水溶液との間に通電（放電を含む）を行
なって、インプラント材表面にアパタイトを析出させる
表面処理方法に於いて、上記通電によるアパタイト析出
処理の前処理として、上記インプラント材(4) を弗化物
水溶液(3) で洗浄しその表面に弗化物を付着させる処理
を行なうことを特徴とするインプラント材の表面処理方
法。1. An implant material is inserted into a mixed aqueous solution of a phosphate and a calcium compound, and an electric current (including discharge) is applied between the implant material and the mixed aqueous solution with the implant material serving as a cathode to form apatite on the surface of the implant material. In the surface treatment method of precipitating, as a pretreatment of the apatite precipitation treatment by the above-mentioned energization, the implant material (4) is washed with an aqueous solution of fluoride (3) and a treatment for adhering fluoride to the surface is performed. Surface treatment method for implant materials.
に所要の熱処理を施すことを特徴とする請求項１に記載
のインプラント材の表面処理方法。2. The surface treatment method for an implant material according to claim 1, wherein a required heat treatment is performed after the apatite precipitation treatment by the energization.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP04014047A JP3140527B2 (en) | 1992-01-29 | 1992-01-29 | Surface treatment method for implant material |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP04014047A JP3140527B2 (en) | 1992-01-29 | 1992-01-29 | Surface treatment method for implant material |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH05285213A true JPH05285213A (en) | 1993-11-02 |
| JP3140527B2 JP3140527B2 (en) | 2001-03-05 |
Family
ID=11850188
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP04014047A Expired - Fee Related JP3140527B2 (en) | 1992-01-29 | 1992-01-29 | Surface treatment method for implant material |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP3140527B2 (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005027930A (en) * | 2003-07-08 | 2005-02-03 | Ishifuku Metal Ind Co Ltd | Bone substitute |
| US8465790B2 (en) | 1993-12-20 | 2013-06-18 | Astrazeneca Ab | Metallic implant and process for treating a metallic implant |
| JP2016504949A (en) * | 2013-02-05 | 2016-02-18 | シュレー、マルクスSCHLEE, Markus | Treatment system for cleaning parts, especially implant parts contaminated with biofilm |
| KR20190035081A (en) * | 2017-09-26 | 2019-04-03 | 김태훈 | Abutment for implant |
-
1992
- 1992-01-29 JP JP04014047A patent/JP3140527B2/en not_active Expired - Fee Related
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8465790B2 (en) | 1993-12-20 | 2013-06-18 | Astrazeneca Ab | Metallic implant and process for treating a metallic implant |
| JP2005027930A (en) * | 2003-07-08 | 2005-02-03 | Ishifuku Metal Ind Co Ltd | Bone substitute |
| JP2016504949A (en) * | 2013-02-05 | 2016-02-18 | シュレー、マルクスSCHLEE, Markus | Treatment system for cleaning parts, especially implant parts contaminated with biofilm |
| US9931422B2 (en) | 2013-02-05 | 2018-04-03 | Zyfoma Gmbh | Treatment system for cleaning a component, in particular an implant part, contaminated with a biofilm |
| US10568979B2 (en) | 2013-02-05 | 2020-02-25 | Zyfoma Gmbh | Treatment system for cleaning a component, in particular an implant part, contaminated with a biofilm |
| KR20190035081A (en) * | 2017-09-26 | 2019-04-03 | 김태훈 | Abutment for implant |
Also Published As
| Publication number | Publication date |
|---|---|
| JP3140527B2 (en) | 2001-03-05 |
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