JPH0526882A - Multiitem simultaneous-processing automatic analyzer and its analysis processing method - Google Patents

Abstract

PURPOSE:To improve analysis efficiency, reduce the running cost of a reagent and prevent the production of contamination by most suitably determining the combination of analysis items, the arrangement of the reagent and the other arrangement of analysis channels from various factors. CONSTITUTION:In the case where many items are analyzed simultaneously, an input device 28 is operated to give a plurality of analysis conditions necessary for inspection and the combination of the optimum analysis items in which analysis efficiency is maximum, the running cost of a reagent is minimum and contamination is not produced, the arrangement of a reagent and the like are determined by the operation on the basis of the conditions given by the use of CPU 27. And the multi-item simultaneous analyses are executed. A rack of a rack sampler part 6 is sent out, the partial injection of an inspection object of an inspection object vessel 3a, the other partial infection of the reagent, the agitation of a reaction liquid, absorption coefficient measure, washing of the vessel and the like are repeated every analysis cycle as soon as analysis preparation operation like washing by the use of a washing mechanism 22. The reduction of the influence of contamination and the running cost of the reagent is contrived as soon as processing efficiency is heightened from the setting of the analysis channel.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a multi-item simultaneous processing automatic analysis apparatus and an analysis processing method thereof, and more particularly to a multi-item simultaneous processing analysis apparatus for simultaneously analyzing a plurality of analysis items and improving the efficiency of the analysis processing. Analysis processing method.

[0002]

2. Description of the Related Art Among automatic analyzers for biochemistry for clinical examination, there are conventionally automatic analyzers for simultaneously testing a plurality of analysis items for a large number of specimens.
This automatic analyzer is called a multi-item simultaneous processing automatic analyzer. In this type of automatic analyzer, for each sample to be analyzed, a plurality of analysis items are determined in advance according to the object or purpose of the test, and the analysis method is performed so that the determined plurality of analysis items are analyzed simultaneously. Composed. Here, an "analysis block" is defined. The analysis block is a unit that is determined by the arrangement of the reagents installed in the device, and in a certain analysis cycle, samples are simultaneously dispensed, reagents are simultaneously ejected, and photometry is performed simultaneously.

Further, in the above-mentioned automatic analyzer, a set inspection is performed as a form of the inspection method. "Set inspection"
Is the unit of analysis request as seen from the side of requesting analysis. Explaining the set test in detail, for example, a user such as a hospital or a test center can select a liver function system, a kidney function system, a digestive system, a circulatory system, an inpatient dock or an outpatient dock in a multi-item simultaneous processing automatic analyzer. In each inspection such as, a plurality of analysis items are set as a set according to the purpose of each inspection, and the plurality of analysis items are performed by one analysis process. The type of set test and the number of tests vary greatly from hospital to hospital. For example, a hospital that mainly treats heart diseases often has a set examination of the circulatory system, and a hospital that mainly treats diseases of the stomach and the intestines often has a set examination of the digestive system.

Further, regarding the problem of contamination in an automatic analyzer for simultaneous processing of multiple items, it has been attempted to avoid the contamination manually by an operator.
That is, since the number of combinations of analysis items that cause contamination is small in a plurality of analysis items, the operator manually determines the combinations that do not cause contamination each time.

As a conventional technique of an automatic analyzer capable of measuring many items, Japanese Patent Laid-Open No. 58-88663 is cited. This automatic analyzer automatically determines the order of measurement items when performing multi-measurement measurements in chemical analysis, thus reducing the burden on the measurer.

[0006]

In the conventional multi-item simultaneous processing automatic analysis apparatus, there are cases where analysis processing is not requested for all the items of a predetermined analysis block that can be simultaneously processed. In this case, a high efficiency has been dealt with by adopting a block-by-block random access method that proceeds to the next block inspection without delaying the analysis cycle.

However, in the conventional multi-item simultaneous processing automatic analyzer, when the user actually analyzes the analysis item and the number of analysis, the breakdown of the set inspection and the number of inspection, and further the inside of the reagent dispensing channel, It was not attempted to minimize the running cost by considering the amount of each reagent consumed. Therefore, there is a problem in that the analytical processing capacity of the multi-item simultaneous processing automatic analyzer cannot be maximized.

Furthermore, the conventional method for avoiding contamination in a multi-item simultaneous processing automatic analyzer is extremely troublesome because it is a manual work, and it raises a problem that the capacity of the automatic analyzer is reduced. Was there.

The automatic analyzers according to the above-mentioned prior art documents also attempt to automate the determination of measurement order in multi-item analysis, but the above-mentioned meaning of maximizing the analytical processing capacity of the multi-item simultaneous processing automatic analyzer. Then, it is not enough.

An object of the present invention is to provide an optimum combination of a plurality of analysis items which maximizes the analysis processing efficiency, minimizes the running cost of reagents, and prevents the occurrence of contamination in an automatic analyzer for multi-item simultaneous processing. Arrangement of reagents,
An object of the present invention is to provide a multi-item simultaneous processing automatic analysis apparatus and an analysis processing method for automatically calculating and determining the arrangement of analysis channels.

[0011]

A first analysis processing method of a multi-item simultaneous processing automatic analysis apparatus according to the present invention comprises a known analysis section and a sample transport apparatus for transporting a plurality of samples to the analysis section. It is an analysis processing method of an automatic analyzer that specifies multiple analysis items for one sample and analyzes multiple analysis items at the same time in the analysis unit. Set analysis details and the number of tests as analysis conditions, and based on the analysis conditions, determine the combination of analysis items and the arrangement of reagents that maximize the processing efficiency in simultaneous analysis, and the determined analysis. The analysis unit executes the analysis according to the combination of the items and the arrangement of the reagents.

A second analytical processing method for a multi-item simultaneous processing automatic analyzer according to the present invention comprises at least two known analytical sections and a sample transport apparatus for transporting a plurality of samples to each of the analytical sections. It is an analysis processing method of an automatic analyzer that specifies multiple analysis items for one sample and analyzes multiple analysis items at the same time in each analysis unit. Set analysis items and the number of tests as analysis conditions, and based on the analysis conditions, the combination of analysis items and the reagent arrangement that maximizes the processing efficiency in simultaneous analysis, and the arrangement of analysis items for each analysis section. And a step of determining
According to the determined combination of analysis items and the arrangement of reagents and the arrangement of analysis items, each analysis unit is configured to perform an analysis.

In each of the above analytical processing methods,
It is also possible to add and combine analysis conditions for the purpose of reducing the running cost of reagents and preventing contamination, and calculate and determine the combination of analysis items.

The first multi-item simultaneous processing automatic analysis apparatus according to the present invention comprises a known analysis section and a sample transporting apparatus for transporting a plurality of samples to the analysis section, and a plurality of analysis items for one sample. Designate and analyze multiple analysis items at the same time in the analysis unit. At least enter the expected analysis items and the number of analyzes, the breakdown of the set inspection that analyzes multiple analysis items and the number of inspections as analysis conditions. And a combination of the analysis items determined by the calculation processing unit and the calculation processing unit that calculates the arrangement of the reagents and the arrangement of the reagents that maximizes the processing efficiency in the simultaneous analysis based on the input analysis conditions. And an analysis execution unit that causes the analysis unit to execute analysis according to the arrangement of the reagents.

A second multi-item simultaneous processing automatic analyzer according to the present invention comprises at least two known analysis units and a sample transport device for transporting a plurality of samples to each analysis unit. The analysis items are specified and multiple analysis items are analyzed at the same time in each analysis unit. At least the expected analysis items and the number of analyzes, and the breakdown of the set inspection and the number of inspections that analyze multiple analysis items at the same time. Based on the input means for inputting the analysis conditions, the combination of the analysis items and the reagent arrangement that maximize the processing efficiency in the simultaneous analysis, and the arrangement of the analysis items in charge of each analysis unit are calculated based on the input analysis conditions. An arithmetic processing unit and an analysis executing unit that causes each analysis unit to perform analysis according to the combination of analysis items and the arrangement of reagents and the arrangement of analysis items determined by the arithmetic processing unit are provided.

Each of the automatic analyzers may include an output means for displaying the calculation result obtained by the calculation processing means.

The purpose of improving the analysis processing efficiency is achieved by analyzing the analysis items set as one set inspection simultaneously as much as possible. When there are a plurality of set inspections, priority is given to the set inspections in descending order of inspection requests, and analysis is performed in descending order. The purpose of minimizing the running cost of the reagent is to consider the difference in the amount of reagent used for analyzing the sample, as well as the difference in the amount of reagent consumed when washing the inside of the reagent dispensing channel by the analysis channel, This is achieved by minimizing the running cost of reagents. The purpose of avoiding contamination is achieved by replacing the analysis channels in the combination of analysis items (analysis block) to be analyzed at the same time, while taking into consideration the matters described in the first means for achieving the purpose. .

[0018]

In the present invention, the analysis items set as one set inspection are analyzed at the same time. When there are a plurality of set inspections, the analysis in the order of higher priority of the set inspection requires a plurality of analysis items. If it is done, it will increase the ratio of analyzing each of those analysis items at the same time.
Since all of the multiple analysis items are analyzed with the minimum number of analysis cycles, it is possible to proceed to the analysis of the next analysis item and the next sample most efficiently, and the processing efficiency of the multi-item simultaneous processing automatic analyzer To improve.

In addition, in order to minimize the running cost of the reagent in consideration of the difference in the amount of the reagent for cleaning the inside of the reagent dispensing channel, it is necessary to determine how often the user of the automatic analyzer cleans the inside of the reagent channel. Since the running cost of the reagent can be calculated from the amount of reagent consumed for cleaning the inside of the flow channel and the amount of reagent used for analysis of the sample obtained from the calculation, consider the length of the reagent dispensing flow channel. Multiple reagents can be used by setting expensive reagents in analysis channels with short reagent channels to reduce the reagent consumption required for channel cleaning, and by setting inexpensive reagents in analysis channels with long reagent channels. Furthermore, the avoidance of contamination is performed by exchanging the analysis channels in the combination of analysis items.

[0020]

Embodiments of the present invention will be described below with reference to the accompanying drawings. FIG. 1 shows, as an example, the configuration of an automatic analyzer capable of processing up to 32 analysis items. This automatic analyzer is roughly divided into a sample transport section 1 and one analysis section 2
Composed of and.

First, the sample transport section 1 includes a motor, a belt,
A transport drive mechanism section (not shown) including an arm,
For example, a rack sampler unit 6 for setting a rack 4 containing five sample containers 3 and a plurality of set racks 4
And a line sampler section 7 for transporting one by one to a position near the analysis section 2 in a line. The transport drive mechanism unit moves the plurality of racks 4 one by one at a predetermined timing and moving speed. Each rack 4 finally returns to the rack sampler unit 3 again. In the figure, the moving state of each rack 4 is indicated by an arrow 5.

On the other hand, the analysis section 2 mainly comprises a translucent reaction container 8 formed of glass or plastic for mixing a sample and a reagent to cause a color reaction, and the reaction container 8 is circular. A reaction table 9 arranged and held on the circumference (in the illustrated example, two rows of circumferences), a drive mechanism (not shown for convenience of description) for rotating the reaction table 9, and a vicinity of the analysis unit 2. The samples in the sample containers 3 accommodated in the moved rack 4 are simultaneously divided into a plurality of reaction containers 8 (two in the inner peripheral side reaction container and two in the outer peripheral side, a total of four in the illustrated example). Pipette 10 and sampling mechanism 11 for pouring
And a plurality of sample dispensing mechanisms 12 (in this embodiment,
Any one of the plurality of reagent containers 13 and a cool box 14 for keeping the reagent container 13 of the first reagent for each of the maximum 32 analysis items and, if necessary, a maximum of 64 reagent containers 13 in total. Reagent 15 is appropriately selected according to the analysis item, and is simultaneously dispensed into a plurality of reaction vessels 8 (in the illustrated example, two in the inner peripheral side reaction vessel and two in the outer peripheral side 4 in total). For dispensing, a reagent dispensing mechanism 19 including a dispenser 16, a reagent dispensing flow path 17, and a reagent nozzle 18, and a stirring mechanism 20 for stirring the reaction liquid after the sample and the reagent 15 are dispensed into the reaction container 8. A photometer 21 for measuring the absorbance of the reaction solution
And a cleaning mechanism 22 for suctioning and removing the reaction solution from the reaction container 8 that has completed the analysis, and then cleaning and preparing the reaction container 8 for use in the next analysis.

Regarding the reagent dispensing mechanism, a second reagent dispensing mechanism is provided for the first reagent dispensing mechanism 19 as required. The second reagent dispensing mechanism is designated by reference numeral 19 'in the figure.

Further, the signal output from the photometer 21 of the analysis unit 2 is LOG-converted by the analysis unit CPU 23, 23a, A /
The processing of the D converter 23b is performed, then the digital processing is performed, and the digital processing is transmitted to the operation unit 24. The operation unit 24 is C
The RT 25, the printer 26, the CPU 27, and the input device 28 are used to make arrangements such as statistical processing of transmitted data and output the processing result to the CRT 25 or the printer 26 according to an instruction from the apparatus user.

When multiple items are simultaneously analyzed in a set test for a plurality of samples using this automatic analyzer, the operator who executes the analytical test operates the input device 28 to perform a series of analytical tests. Give multiple analytical conditions required for. These analysis conditions are stored in the memory of the CPU 27. Based on the given analysis conditions, the CPU 27 arithmetically determines the optimum analysis item combination that maximizes the analysis efficiency, minimizes the reagent running cost, or does not cause contamination, and arranges the reagents. To do.
Then, in the analysis, the multi-item simultaneous analysis is executed according to the combination of the analysis items obtained by the calculation. The detailed operation flow in the CPU will be described later.

In the multi-item simultaneous processing automatic analyzer having the above-mentioned configuration, a method is adopted in which the reagent dispensing flow path 13 is switched with four preset analysis items as one block. The plurality of analysis items are always analyzed simultaneously in the automatic analyzer. If all the analysis items of a block are not requested, the efficiency will be improved by adopting the 4-item unit random access method that advances the analysis to the next analysis item without delaying the analysis cycle as in the past.

Next, the analysis operation of the multi-item simultaneous processing automatic analyzer having the above structure will be described. The characteristics of the analysis processing method according to the present invention will be clarified by the description of the analysis operation.

Sample containers such as test tubes containing samples such as serum and urine are mounted on the rack 4 in a single row, for example, as a set of five containers. These 5 sample containers are referred to as 3a to 3e, respectively. The rack 4 is set on the rack sampler unit 6 of the sample transport unit 1. When the analysis of the automatic analyzer starts, an analysis preparation operation such as washing of the reaction container 8 by the washing mechanism 22 is performed, and at the same time, the rack sampler unit 6
Rack 4 is sent out. The rack 4 sent out is
The sample is transferred by the line sampler unit 7 and stopped at the sample dispensing position of the analysis unit 2. By the sample dispensing mechanism 12, a plurality of samples (two in the inner peripheral side reaction container and two in the outer peripheral side reaction container, a total of four in total) of the reaction containers 8 are contained in the sample container 3a. Each of them is dispensed at the same time by a predetermined amount required for analysis. The reaction table 9 rotates by a predetermined rotation angle (for example, half rotation + two reaction vessels) in each analysis cycle. The four reaction containers 8 into which the sample has been dispensed stop at the reagent dispensing position. Here, the reagent 15 of the analysis item requested in advance is dispensed into the reaction container 8 by the reagent dispensing mechanism 19 in a designated amount. At the same time, at the sample dispensing position, another sample contained in the next sample container 3b is dispensed into another reaction container 8. In the subsequent analysis cycle (in the figure, after two analysis cycles), the sample to which the reagent 15 has been added is stirred by the stirring mechanism 2.
The reaction solution is stirred by 0. As a result, the reaction container 8 exhibits a color reaction depending on the concentration. The rotation of the reaction table 9 for each analysis cycle causes the reaction container 8 to move to the photometer 2
The absorbance of the reaction liquid in the reaction container 8 is measured when passing before 1. As described above, in each analysis cycle, the sample in the sample container 3a is dispensed, the reagent is dispensed, the reaction solution is stirred, and if necessary, the second reagent is dispensed and stirred at a predetermined position,
Repeat the measurement of absorbance and washing of the reaction vessel after the measurement. In the above, when the sample dispensing for all the analysis items requested for one sample, for example, the sample in the sample container 3a is completed, the next sample (sample in the sample container 3b) is moved to the sample dispensing position. The line sampler unit 7 transfers and stops the rack 4, and continues dispensing and analysis.

The following points are taken into consideration in the analysis processing method of the aforementioned multi-item simultaneous processing automatic analyzer.

When a plurality of analysis items are always set and inspected, for example, if a specific 8 items are always inspected as a set, the analysis channel of the above-described automatic analysis device is set to 8 blocks in 2 blocks. If (1st example) is set, the dispensing of the requested 8 items will be completed by dispensing the sample twice with 4 items each. On the other hand, if each of the eight items is divided into completely different blocks and the analysis channel is set (second example), it is necessary to dispense the sample eight times for each item. In this way, depending on the setting method of the analysis channel,
A difference occurs in the number of sample dispensing, that is, the number of analysis cycles. A comparison of the two examples above with a second comparison with the first example.
As can be seen from the fact that the processing capacity of the above example decreased to 1/4, in the automatic analyzer that employs the random access method in units of multiple items, there is a big difference in the actual processing capacity depending on the setting of the analysis channel. Occurs.

Further, it is not necessary to simply set the analysis channel by summarizing the set inspection as much as possible. Users of multi-item simultaneous processing automatic analyzers will perform multiple sets of tests with different breakdowns according to the purpose of each test of liver function system, renal function system, digestive system, circulatory system, hospital dock, outpatient dock, etc. In many cases, there are many duplicated analysis items in the set inspection. Furthermore, the breakdown of the same set inspection differs for each user of the automatic analyzer, and the number of set inspections also differs. Therefore, prioritizing taking into account the breakdown of set inspections with a large number of inspection requests and the duplication of analysis items,
It is necessary to set the analysis channel in the order of the analysis items with the highest rank.

Further, there is a problem of contamination.
Contamination is a phenomenon in which a previously analyzed item or sample affects the next analysis result. In the automatic analyzer that employs the random access method, one reaction container is repeatedly used for the analysis of multiple items. Therefore, depending on the material of the reaction container, a reagent containing an enzyme that is easily adsorbed in the reaction container. If the above analysis is performed, the next analysis may affect the analysis result. For example, UA (uric acid) or CREA (creatinine) by the enzymatic method is analyzed in the reaction vessel 8 in which CHO (cholesterol) is analyzed, or T
When G (neutral fat) and lipase are analyzed in the same reaction vessel, the analysis result is affected. In order to avoid the effect of this contamination and not to reduce the processing efficiency of the analysis, either switch the analysis channels in the same block or, if this is not possible, analyze in the inspection blocks with similar priority. Switch to another channel. By doing so, the analysis is not performed in the same reaction vessel, the processing efficiency of the analysis is not reduced, and the influence of contamination can be avoided.

Next, the cleaning cost of the reagent dispensing channel and the running cost of the reagent in the above-described analysis operation will be described.

In an automatic analyzer for multi-item simultaneous processing, a plurality of reagent containers 13 are stored in a cool box 14 and the reagent dispensing mechanism 1 is used.
The reagent 15 necessary for analysis is passed through the reagent dispensing channel 17 of 9
Is dispensed into the reaction container 8. However, when the reagent 15 stays in the reagent dispensing flow path 17, the quality of the reagent 15 deteriorates with the passage of time, and when the reagent container 13 is replaced, air enters or is replaced in the reagent dispensing flow path 17. Previous old reagent 1
5 affects the analysis result. Therefore, in order to avoid this effect, a flow passage washing operation of washing the inside of the reagent dispensing flow passage 17 with water and further replacing with the reagent 15 is performed as a maintenance operation separately from the analysis operation. Due to the configuration of the device, the length of the reagent dispensing channel 17 is set at the position where the reagent container 13 is set,
That is, since it differs depending on the analysis channel, the amount of reagent consumed for cleaning the flow channel also differs depending on the analysis channel.

The running cost of the reagent depends on the amount of the reagent used for the analysis of the sample, the amount of reagent consumed for cleaning the flow path, the dead volume of the reagent remaining in the container when the reagent container is replaced, and the flow path cleaning by the user of the automatic analyzer. It is calculated from the frequency of performing and the price of reagents. To minimize this running cost, expensive reagents are set in the analysis channel with a short reagent flow path to reduce the reagent consumption required for cleaning the flow path, and inexpensive reagents are set in the analysis channel with a long reagent flow path. Etc. by taking into consideration the length of the reagent dispensing channel. By thus changing the analysis channel for setting the reagent, the running cost of the reagent of the entire apparatus is minimized.

FIG. 2 shows an operation flow of the analysis processing method realized in consideration of the above matters. This operation flow makes it clear how to determine the analysis channel. The contents of each step of the operation flow shown in FIG. 2 are as follows.

Step 31 of the preparatory work; the following works 1 to 9 are carried out. 1. Prioritize set inspections in descending order of the number of inspection requests. 2. List common analysis items for each set inspection. 3. Give different priority to each analysis item. 4. In consideration of the set inspection priority, sort the analysis items in descending order of priority. 5.4 Divide into inspection blocks for each item. 6. Calculate the reagent price for each test block and arrange them in descending order of price. 7. (Omitted in the embodiment of FIG. 1 in which there is one analysis unit.) 8. The test block with the higher reagent price is allocated to the flow path block with the shorter reagent dispensing flow path. 9. Allocate reagents to analysis channels to minimize reagent running costs.

Step 32 of judgment 1; Are there any contaminations in the analysis items in the same analysis channel of different inspection blocks? If NO, the process ends, and if YES, the process proceeds to step 33.

Step 3 of reallocation of analysis channels
3; Allocate analysis channels within the same test block.

Step 34 of decision 2; Has an analysis channel been allocated within the same test block? That is, has the analysis channel allocated in step 33 been previously determined in step 32? If YES, the process proceeds to step 32, and if NO, the process proceeds to step 35.

Step 35 of reallocation of analysis channels in block units; the allocation of inspection blocks and flow path blocks is changed.

Another embodiment of the present invention will be described with reference to FIG. FIG. 3 shows an automatic analyzer having an analysis processing capacity of up to 40 items, which includes a sample transport unit 101 and two analysis units 102A and 102B of up to 20 items.
Other configurations are the same except that there are two analysis units and each analysis unit has a related part. In FIG. 3, the same elements as those described in FIG. 1 are designated by the same reference numerals, and the description thereof will be omitted.

Even in the automatic analyzer of this embodiment, the basic part of the high-efficiency processing method shown in FIG. 2 does not change except that the analysis work load is equally allocated to each of the two analysis units 102A and 102B. . The operation flow of the multi-item simultaneous processing automatic analyzer according to this embodiment is as follows.

Step 31 of the preparatory work; the following works 1 to 9 are carried out. 1. Prioritize set inspections in descending order of the number of inspection requests. 2. List common analysis items for each set inspection. 3. Give different priority to each analysis item. 4. In consideration of the set inspection priority, sort the analysis items in descending order of priority. 5.4 Divide into inspection blocks for each item. 6. Calculate the reagent price for each test block and arrange them in descending order of price. 7. The inspection blocks are assigned to the respective analysis units according to the priority order of the inspection blocks so that the workload of each analysis unit becomes equal. 8. The test block with the higher reagent price is allocated to the flow path block with the shorter reagent dispensing flow path. 9. Allocate reagents to analysis channels to minimize reagent running costs.

Step 32 of Judgment 1; Are there any contaminations in the analysis items in the same analysis channel of different inspection blocks? If NO, the process ends, and if YES, the process proceeds to step 33.

Step 3 of reallocation of analysis channels
3; Allocate analysis channels within the same test block.

Step 34 of decision 2; whether analysis channel is allocated in the same test block? That is, has the analysis channel allocated in step 33 been previously determined in step 32? If YES, the process proceeds to step 32, and if NO, the process proceeds to step 35.

Step 35 of reallocation of analysis channels in block units; the analysis channels are replaced in block units with flow channel blocks of other analysis units, which have the same or similar reagent dispensing flow path lengths.

The difference in the operation flow between this embodiment and the above embodiment is that the work 7 is added in step 31 and the contents of step 35 are changed.

[0050]

As is apparent from the above description, according to the present invention, in the multi-item simultaneous processing automatic analysis device, the analysis item and the analysis number actually analyzed by the user, the breakdown of the set inspection and the inspection number, Considering the frequency with which the user cleans the channel and the running cost and contamination of the reagent calculated from the consumption, the processing efficiency of the device is maximized, the running cost of the reagent is minimized, and the occurrence of contamination is prevented. Since the combination of the analysis items, the arrangement of the reagents, and the arrangement of the analysis channels to be performed are determined, the substantial processing capacity of the multi-item simultaneous processing automatic analyzer can be improved.

[Brief description of drawings]

FIG. 1 is an overall configuration diagram of a multi-item simultaneous processing automatic analyzer according to an embodiment of the present invention.

FIG. 2 is an operation flowchart for determining the arrangement of analysis channels in the multi-item simultaneous processing automatic analyzer of the present invention.

FIG. 3 is an overall configuration diagram of a multi-item simultaneous processing automatic analyzer according to another embodiment of the present invention.

[Explanation of symbols]

1 Sample transport section 2 analysis department 3 sample containers 4 racks 8 reaction vessels 9 Reaction table 10 pipettors 12 Sample dispensing mechanism 13 Reagent container 14 cold storage 15 reagents 18 Reagent dispensing mechanism 20 stirring mechanism 21 Photometer 22 Cleaning mechanism 23 Analytical CPU 24 Operation part 25 CRT 26 Printer 27 CPU 28 Input device

Claims (7)

[Claims] 1. A translucent reaction container for mixing a sample and a reagent to carry out a color reaction, a reaction table for holding a plurality of said reaction containers on a circumference, and rotating this reaction table. Rotational drive mechanism, sample dispensing mechanism that dispenses the sample into multiple reaction vessels simultaneously, reagent storage that stores multiple reagents, and dispenses the reagents into multiple reaction vessels simultaneously according to the analysis item A reagent dispensing mechanism, a reagent dispensing channel that connects the reagent storage device and the reagent dispensing mechanism, a stirring mechanism that stirs the reaction solution after the sample and the reagent are dispensed into the reaction container, and a plurality of A photometer for simultaneously measuring the absorbance of the reaction solution, and a reaction container cleaning mechanism for removing the reaction solution from the reaction container after the analysis by suction to wash it for subsequent analysis, and Transport multiple samples to the analysis unit An analysis processing method of an automatic analysis device, comprising a sample transporting device, designating a plurality of analysis items for one sample, and simultaneously analyzing a plurality of the analysis items in the analysis unit. A step of giving the breakdown of the set test and the number of tests as analysis conditions for simultaneously analyzing a plurality of analysis items, and based on the analysis conditions, the combination of analysis items and the arrangement of reagents that maximize the processing efficiency in simultaneous analysis are determined by calculation. And a step of performing analysis by the analysis unit according to the determined combination of analysis items and the arrangement of reagents, the analysis processing method of the multi-item simultaneous processing automatic analyzer. 2. A translucent reaction container for mixing a sample and a reagent to carry out a color reaction, a reaction table for holding a plurality of said reaction containers on a circumference, and rotating this reaction table. Rotational drive mechanism, sample dispensing mechanism that dispenses the sample into multiple reaction vessels simultaneously, reagent storage that stores multiple reagents, and dispenses the reagents into multiple reaction vessels simultaneously according to the analysis item A reagent dispensing mechanism, a reagent dispensing channel that connects the reagent storage and the reagent sentence mechanism, a stirring mechanism that stirs the reaction liquid after the sample and the reagent are dispensed into the reaction container, and a plurality of At least two analyzers each comprising a photometer for simultaneously measuring the absorbance of the reaction liquid and a reaction container cleaning mechanism for removing the reaction liquid by suction from the reaction container that has been analyzed and cleaning it for subsequent analysis , Multiple samples An analysis processing method of an automatic analysis device, comprising a sample transporting device for transporting to each of the analysis units, designating a plurality of analysis items for one sample, and simultaneously analyzing a plurality of the analysis items in each of the analysis units, Expected analysis items and number of analysis, a step of giving the breakdown of the set inspection and the number of inspections that analyze multiple analysis items at the same time as analysis conditions, and based on the analysis conditions, the analysis items that maximize processing efficiency in simultaneous analysis The step of deciding the combination and the arrangement of reagents and the arrangement of the analysis items to be handled by each of the analysis units, and the respective analysis units according to the determined combination of the analysis items and the arrangement of the reagents and the arrangement of the analysis items. An analysis processing method for a multi-item simultaneous processing automatic analysis apparatus, which comprises the step of performing an analysis. 3. The analysis processing method for a multi-item simultaneous processing automatic analyzer according to claim 1, wherein the reagent deteriorates in quality in the reagent dispensing channel with the passage of time, or in the reagent storage device. In order to avoid the influence on the analysis result of the old reagent remaining in the reagent dispensing channel when replacing the reagent container, the step of cleaning the reagent dispensing channel is included, and the inside of the reagent dispensing channel is cleaned. Add the running cost of the reagent calculated from the amount of reagent consumed at the time and the frequency of cleaning the flow path to the analysis conditions, and set the analysis items to maximize the treatment efficiency and minimize the running cost of the reagent. An analysis processing method for a multi-item simultaneous processing automatic analysis apparatus, which is characterized by determining a combination and the like. 4. An analysis processing method for a multi-item simultaneous processing automatic analysis apparatus according to claim 1, wherein the reaction container has the same influence of the items previously analyzed in a specific reaction container. In the analysis processing method of the multi-item simultaneous processing automatic analysis apparatus, which is characterized by adding the contamination that affects the next analysis to the analysis conditions and determining the combination of analysis items so that the processing efficiency is maximized. . 5. A translucent reaction container for mixing a sample and a reagent to carry out a color reaction, a reaction table for holding a plurality of said reaction containers on a circumference and rotating this reaction table. Rotational drive mechanism, sample dispensing mechanism that dispenses the sample into multiple reaction vessels simultaneously, reagent storage that stores multiple reagents, and dispenses the reagents into multiple reaction vessels simultaneously according to the analysis item A reagent dispensing mechanism, a reagent dispensing channel that connects the reagent storage device and the reagent dispensing mechanism, a stirring mechanism that stirs the reaction solution after the sample and the reagent are dispensed into the reaction container, and a plurality of A photometer for simultaneously measuring the absorbance of the reaction solution, and a reaction container cleaning mechanism for removing the reaction solution from the reaction container after the analysis by suction to wash it for subsequent analysis, and Transport multiple samples to the analysis unit An automatic analyzer that includes a sample transporting device, specifies a plurality of analysis items for one sample, and simultaneously analyzes a plurality of the analysis items in the analysis unit, at least an expected analysis item, the number of analyzes, and a plurality of analyzes Input means for inputting the breakdown of the set examination and the number of examinations as the analysis conditions for simultaneously analyzing the items, and the combination of the analysis items and the arrangement of the reagents that maximize the processing efficiency in the simultaneous analysis based on the inputted analysis conditions. A multi-item simultaneous processing automatic analysis, characterized by comprising: an arithmetic processing means for arithmetically operating and an analysis execution means for causing the analysis part to perform an analysis in accordance with the combination of analysis items and the arrangement of reagents determined by the arithmetic processing means apparatus. 6. A translucent reaction container for mixing a sample and a reagent to carry out a color reaction, a reaction table for holding a plurality of the reaction containers on a circumference, and rotating this reaction table. Rotational drive mechanism, sample dispensing mechanism that dispenses the sample into multiple reaction vessels simultaneously, reagent storage that stores multiple reagents, and dispenses the reagents into multiple reaction vessels simultaneously according to the analysis item A reagent dispensing mechanism, a reagent dispensing channel that connects the reagent storage and the reagent sentence mechanism, a stirring mechanism that stirs the reaction liquid after the sample and the reagent are dispensed into the reaction container, and a plurality of At least two analyzers each comprising a photometer for simultaneously measuring the absorbance of the reaction liquid and a reaction container cleaning mechanism for removing the reaction liquid by suction from the reaction container that has been analyzed and cleaning it for subsequent analysis , Multiple samples At least expected in an automatic analyzer that is equipped with a sample transporting device for transporting to each of the analysis units, specifies a plurality of analysis items for one sample, and analyzes the plurality of analysis items at the same time in each of the analysis units. An analysis item that maximizes the processing efficiency in simultaneous analysis, based on the analysis item and the number of analyzes, the input means for inputting the set inspection details and the number of inspections that simultaneously analyze multiple analysis items as analysis conditions, and the analysis conditions that have been input. And the arrangement of reagents, arithmetic processing means for calculating the arrangement of the analysis items in charge of each of the analysis unit, according to the combination of the analysis items and the arrangement of the reagents and the arrangement of the analysis items determined by the arithmetic processing means, An automatic analyzer for multi-item simultaneous processing, comprising: an analysis executing means for causing each of the above-mentioned analysis units to execute an analysis. 7. The multi-item simultaneous processing automatic analysis device according to claim 5 or 6, further comprising output means for displaying a calculation result obtained by the calculation processing means. .