WO2015087393A1 - Automatic analysis system formed by linking plurality of analysis devices - Google Patents

Automatic analysis system formed by linking plurality of analysis devices Download PDF

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Publication number
WO2015087393A1
WO2015087393A1 PCT/JP2013/083083 JP2013083083W WO2015087393A1 WO 2015087393 A1 WO2015087393 A1 WO 2015087393A1 JP 2013083083 W JP2013083083 W JP 2013083083W WO 2015087393 A1 WO2015087393 A1 WO 2015087393A1
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WO
WIPO (PCT)
Prior art keywords
reagent
information
automatic
sample
unit
Prior art date
Application number
PCT/JP2013/083083
Other languages
French (fr)
Japanese (ja)
Inventor
清浩 杉山
Original Assignee
株式会社島津製作所
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Application filed by 株式会社島津製作所 filed Critical 株式会社島津製作所
Priority to PCT/JP2013/083083 priority Critical patent/WO2015087393A1/en
Publication of WO2015087393A1 publication Critical patent/WO2015087393A1/en

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/0092—Scheduling
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/026—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having blocks or racks of reaction cells or cuvettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00178—Special arrangements of analysers
    • G01N2035/00326—Analysers with modular structure
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00594—Quality control, including calibration or testing of components of the analyser
    • G01N35/00613—Quality control
    • G01N35/00663—Quality control of consumables
    • G01N2035/00673—Quality control of consumables of reagents

Definitions

  • the present invention relates to an automatic analysis system configured by connecting a plurality of analyzers.
  • the automatic analyzer is configured to automatically sample and analyze the sample contained in the container.
  • a mechanism for transporting a sample as a mechanism for transporting a sample, a belt conveyor for mounting and transporting a sample rack holding a plurality of sample containers, and a sample rack transported to a predetermined position by the belt conveyor are taken out from the belt conveyor.
  • a mechanism such as an arm that transports the sample to a predetermined sampling position is provided (for example, see Patent Document 1).
  • an installation unit for an operator to install a sample rack is provided on the start side of the belt conveyor, and a sample rack collection unit for collecting the sample rack after sampling is provided on the end side.
  • the sample rack is transported by the belt conveyor, and is transported to another sampling position by the arm at a predetermined position to perform sampling on the sample container.
  • the sample rack that has been sampled is returned again onto the belt conveyor by the arm, and is transported to the sample rack recovery section on the terminal side by the belt conveyor and collected.
  • an object of the present invention is to provide an automatic analysis system capable of automatically introducing and analyzing common sample containers sequentially in a plurality of automatic analyzers.
  • An automatic analysis system includes a plurality of automatic analyzers, a sample transport device that is arranged between adjacent automatic analyzers among the automatic analyzers and connects adjacent automatic analyzers, and an automatic analyzer It is provided with an arithmetic and control unit that is connected to all of the sample transport devices and manages the operation of the entire automatic analysis system.
  • Each of the automatic analyzers includes a belt conveyor that transports a sample rack that holds a sample container, a reagent installing unit that installs a plurality of reagents, a sample is collected from the sample container, and a reagent in the reagent installing unit is added to the sample.
  • a sampling analysis unit that performs analysis by reaction and a sample introduction mechanism that holds the sample rack on the belt conveyor and introduces the sample rack to the sampling analysis unit are provided.
  • the sample transport device includes a transport mechanism that holds a sample rack at the end of one belt conveyor among the automatic analyzers adjacent to each other and transports the sample rack to the start end of the other belt conveyor.
  • the automatic analysis system of the present invention includes reagent information acquisition means for acquiring information on the reagents installed in the reagent installation section of each automatic analyzer, and the arithmetic and control unit is executed in any of the automatic analyzers.
  • All the reagents used in one analysis item as one of the rules for the reagents installed in the reagent installation section of each automatic analyzer, the item information holding section that holds the information of the reagents used in the possible analysis items A rule holding unit that holds a rule that must be installed in one automatic analyzer, and a rule violation determination unit that determines whether or not a reagent installed in a reagent installation unit of each automatic analyzer violates the rule
  • a rule violation display means configured to display in a manner that can be recognized by the operator when the reagent installed in the reagent installing unit violates the rules. That.
  • the arithmetic and control unit confirms the reagent installed in each automatic analyzer by the reagent information acquisition means for each analysis item specified as the analysis item to be executed on the sample, and performs the specified analysis.
  • the apparatus further includes an item execution device selection means configured to select an automatic analyzer in which all of the reagents used in the items are installed as an automatic analyzer that executes the analysis item. Then, the operator automatically selects the automatic analyzer that executes the analysis item simply by specifying the analysis item, so the operator checks the type of reagent installed in each automatic analyzer and There is no need to select an automatic analyzer for executing the analysis item.
  • each analysis item will be undertaken by one of the analyzers, making it easier for the operator to predict the series of operations of the system and sorting the items.
  • the analysis items can be efficiently analyzed for each sample because it is possible to devise a method or to set samples with similar items requested when setting the sample in the rack. Will be able to run.
  • the rule holding unit also holds a rule that reagent containers of the same type of reagent should not be installed in reagent installing units of different automatic analyzers. If it does so, when it will be in the situation where the same analysis item can be performed in several automatic analyzers, an operator will be alerted and such a situation can be avoided.
  • the information processing unit further includes an information display unit that is connected to the arithmetic control device and displays information, and the arithmetic control device displays a list of information on the reagent containers installed in the reagent installing unit of each automatic analyzer.
  • An information display unit configured to display on the information display unit is further provided, and the rule violation display unit is a reagent that violates the rule in the list of information on the reagent container displayed on the information display unit by the information display unit.
  • An example may be given in which a part of the container information is displayed in a different color from the same part of the information of the other reagent containers.
  • One form of the reagent information acquisition means is configured by an information medium attached to each reagent container and recording information on the reagent container, and an information reader that reads information from the information medium of the reagent container installed in the reagent installing unit. Is.
  • An example of the information medium is a barcode, and the information reader in that case is a barcode reader.
  • reagent information acquisition means may be configured to allow an operator to input information about the reagent container installed in the reagent installation unit and to store the input information.
  • the automatic analysis system of the present invention includes a plurality of automatic analyzers connected by a sample transport device, and a sample rack that has reached the end of one belt conveyor among the adjacent automatic analyzers is connected to the rear stage side by the sample transport device. Because it is automatically transported to the beginning of the belt conveyor of the automatic analyzer, a common sample is automatically introduced and analyzed in a plurality of automatic analyzers that are established as independent automatic analyzers. be able to.
  • a common sample can be introduced into a plurality of automatic analyzers by connecting belt conveyors individually provided to adjacent automatic analyzers by a sample transport device. Therefore, it is not necessary to provide a transport device such as a large belt conveyor that traverses all automatic analyzers.
  • a transport device such as a large belt conveyor that traverses all automatic analyzers.
  • the first-stage automatic analyzer and the second-stage automatic analyzer The specimen cannot be freely moved back and forth between the devices. Therefore, when using multiple reagents for a certain analysis item, if those reagents are placed in different automatic analyzers, the specimen cannot be freely moved back and forth within the multiple automatic analyzers. It can happen that the analysis item cannot be completed.
  • one analysis item is always completed by one automatic analyzer.
  • the reagent containers of all the reagents used in the analysis item must be installed in the reagent installing unit of one automatic analyzer, and the rule is held in the rule holding unit.
  • rule violation determining means for determining whether or not the reagent container installed in the reagent installing unit of each automatic analyzer is against the rules, and the reagent container installed in the reagent installing unit are in accordance with the rules.
  • a rule violation display means configured to display that fact by a method that can be recognized by the operator. This makes it easier for the operator to recognize whether the installation location of the reagent container is correct, and prevents reagents used for the same analysis item from being installed in different automatic analyzers.
  • the automatic analysis system 1 includes two automatic analyzers 2a and 2b, a sample transport device 12, and an arithmetic control device 34 (see FIG. 11) connected to these devices 2a, 2b and 12.
  • the automatic analyzers 2a and 2b are arranged side by side in the X direction, which is one direction in the horizontal plane, and the transport parts 6a and 6b of both the automatic analyzers 2a and 2b are connected by the sample transport device 12.
  • a sample that has been sampled in the front-stage automatic analyzer 2a is introduced into the rear-stage automatic analyzer 2b via the sample transport device 12, and the sample is also received in the rear-stage automatic analyzer 2b. Sampling and analysis.
  • the arithmetic control device 34 will be described later.
  • the front-stage automatic analyzer 2a includes a collection analysis unit 4a, a transport unit 6a, and a sample introduction mechanism 18a.
  • the transport unit 6a includes a belt conveyor 7a (a front-stage conveyor) that transports the sample rack 20 holding the sample containers to one side in the X direction (left side in FIGS. 1 and 2).
  • the periphery of the belt conveyor 7a is covered with a cover.
  • a sample rack arrangement unit 8a is provided on the start end side (right side in FIGS. 1 and 2) of the transport unit 6a, and a sample rack collection unit 10a is provided on the end side (left side in FIG. 1).
  • the covers of the sample rack arranging unit 8a and the sample rack collecting unit 10a can be opened and closed. An operator opens the cover of the sample rack arranging unit 8a and arranges the sample rack on the belt conveyor 7a, or covers the sample rack collecting unit 10a.
  • the sample rack that has been sampled can be taken out by opening.
  • the sample introduction mechanism 18a moves in the Y direction perpendicular to the X direction in the horizontal plane, holds the sample rack 20 on the belt conveyor 7a and introduces it to the collection analysis unit 4a side, or the sample rack 20 that has been sampled is belted. It is placed back on the conveyor 7a.
  • a sample rack introduction section 9a is provided between the sample rack placement section 8a and the sample rack collection section 10a of the transport section 6a, and the sample introduction mechanism 18a is provided with a sample rack before sampling on the belt conveyor 7a from the sample rack introduction section 9a. 20 is transferred into the collection analysis unit 4a, and the sample rack 20 after sampling is returned to the belt conveyor 7a.
  • the collection analysis unit 4a includes a reagent installation unit 22a, a sample rack storage unit 24a, A measurement unit 26a is provided.
  • a plurality of sample racks 20 transferred from the belt conveyor 7a by the sample introduction mechanism 18a are accommodated in the sample rack accommodating portion 24a.
  • the sample rack accommodating portion 24a is a turntable, and the sample container on the sample rack 20 is arranged at a predetermined position when the inhalation probe collects the sample.
  • the reagent installing section 22a is provided with a plurality of reagent holders 23a for installing a reagent container containing a reagent.
  • the reagent information of the reagent container installed in each reagent holder 23a of the reagent installing unit 22a is input by the operator inputting the reagent information of the reagent container installed in the arithmetic control device 34 (see FIG. 11), or each reagent container
  • the barcode information as the information medium attached to the information reader is read by the barcode reader as the information reader, so that it is input to the arithmetic and control unit 34 and what reagent is stored in which reagent holder 23a. It is registered in the arithmetic and control unit 34.
  • the arithmetic and control unit 34 When the operator manually inputs reagent information, the arithmetic and control unit 34 also serves as reagent information acquisition means. When the bar code information is read by the bar code reader, the bar code reader is used. The code and barcode reader realize reagent information acquisition means. As will be described later, the arithmetic and control unit 34 creates a reagent information list indicating which reagents are stored in which reagent holders 23a of the reagent installing unit 22a and displays them in the information display unit 42 (see FIG. 11). It has a display function and can be referred to by the operator.
  • the measurement unit 26a is provided with a plurality of containers for mixing the sample and reagent collected by the inhalation probe, and is configured to optically measure the reaction in the container.
  • the sample rack 20 is stored in the sample rack storage unit 24a by the sample introduction mechanism 18a, the sample container held in the sample rack 20 is disposed at a predetermined position, and the sample is collected by the inhalation probe. Is collected.
  • the collected specimen is injected into a container provided in the measurement unit 26a, and after a reagent corresponding to the analysis item is added by an inhalation probe, the reaction between the specimen and the reagent is optically measured such as absorbance and fluorescence intensity.
  • the latter-stage automatic analyzer 2b has the same configuration as the former-stage automatic analyzer 2a.
  • the starting end of the belt conveyor 7b (rear side conveyor) provided in the transport unit 6b of the automatic analyzer 2b and the end of the front belt conveyor 7a are connected by the sample transport device 12.
  • the sample transport device 12 includes a transport mechanism that holds the sample rack 20 that comes to the end of the front-side belt conveyor 7a and is disposed at the start end of the rear-side belt conveyor 7b, and an openable / closable shielding cover 14 that covers the transport mechanism. ing.
  • the transport mechanism will be described later.
  • a micro switch 30 is provided at an opening / closing portion of the shielding cover 14 of the housing of the sample transporting device 12.
  • the microswitch 30 is switched on / off by contacting a pin 28 provided on the shielding cover 14 side. When the shielding cover 14 is closed, the pin 28 turns the microswitch 30 on, and when the shielding cover 14 is opened, the microswitch 30 is turned off.
  • the transport mechanism of the sample transport apparatus 12 operates only when the shielding cover 14 is closed and the microswitch 30 is turned on, and operates when the shielding cover 14 is opened and the microswitch 30 is turned off. Is supposed to stop.
  • the transport mechanism 100 includes a table 102 having a horizontal plane.
  • the table 102 is supported by a base 118.
  • the horizontal surface of the table 102 is set to be almost the same height as the conveying surfaces of the belt conveyors 7a and 7b arranged at both ends.
  • a position in the vicinity of one end (right side in the figure) of the table 102 in the X direction is a transport start position 103a that starts the transport while holding the sample rack that is the transport target. It arrange
  • the position near the end of the other side (left side in the figure) of the table 102 in the X direction is the sample rack transfer completion position 103b, so that the start end of the rear-stage belt conveyor 7b comes to this transfer completion position 103b. Has been placed.
  • the arm member 104 and the arm member 106 extending in the X direction are disposed opposite to both side edges on the table 102.
  • the arm member 104 and the arm member 106 are driven in the X and Y directions at the side edge of the table 102.
  • the arm member 104 and the arm member 106 move simultaneously in the same direction in the X direction and move in a symmetrical direction around the table 102 with respect to the Y direction.
  • the arm member 104 and a mechanism such as a motor for driving the arm member 106 are accommodated in the base 118.
  • the arm member 104 includes a protrusion 104a at the end on the conveyance start position 103a side, and a protrusion 104b at the end on the transport completion position 103b side.
  • the protrusions 104a and 104b protrude toward the table 102 in the Y direction.
  • a recess (not shown) is provided on the side surface of the sample rack 20.
  • the sample rack 20 is placed on the table 20 such that the concave portion faces outward in the Y direction.
  • the protrusions 104a and 104b are fitted into the recesses of the sample rack 20 and engage with the sample rack.
  • the movement of the arm member 104 in the Y direction is performed between a position where the protrusions 104a and 104b are fitted in the concave portion of the sample rack and a position where the arm member 104 does not contact the sample rack itself.
  • the arm member 106 includes a protrusion 106a facing the inner side (the table 102 side in the Y direction) at the end on the conveyance start position 103a side, and a protrusion 106b facing the inner side also on the transport completion position 103b side.
  • the protrusion 106a and the protrusion 106b are engaged with the rear rear surface (in the traveling direction) of the sample rack.
  • the movement of the arm member 106 in the Y direction is performed between a position where the protrusions 106a and 106b engage with the back surface of the sample rack and a position where the protrusions 106a and 106b do not contact the sample rack.
  • the arm members 104 and 106 constitute a handler that holds the sample rack and slides the table 102 from the transport start position 103a to the transport completion position 103b for transport.
  • This handler constitutes a holding portion at two locations on the conveyance start position 103a side and the transport completion position 103b side.
  • the holding portion on the transport start position 103a side is constituted by the projection 104a of the arm member 104 and the projection 106a of the arm member 106
  • the holding portion on the transport completion position 103b side is constituted by the projection 104b of the arm member 104 and the projection 106b of the arm member 106. Is done.
  • the arm member 104 and the arm member 106 are collectively referred to as “handlers 104, 106”, the holding portions on the transfer start position 103a side of the handlers 104, 106 are referred to as “first holding portions 104a, 106a”, and the transfer completion position 103b side.
  • the holding unit is referred to as “second holding unit 104b, 106b”.
  • the first holding units 104a and 106a sandwich the sample rack from both sides at the end of the handlers 104 and 106 on the transport start position 103a side, thereby fitting the protrusion 104a into the concave portion on one side surface of the sample rack and the sample rack.
  • the rear rear surface on the opposite side is supported by the protrusion 106a.
  • the second holding units 104b and 106b sandwich the sample rack from both sides at the end of the arm members 104 and 106 on the transport start position 103b side, thereby fitting the protrusion 104b into the concave portion on one side of the sample rack and the sample rack.
  • the opposite rear rear surface is supported by the protrusion 106b.
  • the handlers 104 and 106 move in the X direction while holding the sample rack, and transport the sample rack by sliding it on the table 102.
  • the handlers 104 and 106 can be manually moved in the Y direction by the operator when the shielding cover 14 is opened or the power of the sample transport device 12 is turned off due to a power failure or the like.
  • the sample rack can be removed from the handlers 104 and 106, and the operator can take out the sample rack from the sample transport device 12.
  • a guide rail 108 that is fitted in a groove provided on the side surface of the sample rack that slides on the table 102 and prevents the sample rack from falling is provided.
  • a first sensor 110 that detects the arrival of the sample rack at the transfer start position 103a is provided on the side of the transfer start position 103a.
  • a second sensor 112 for detecting the arrival of the sample rack at the transport completion position 103b is provided on the side of the transport completion position 103b.
  • a stopper 114 is provided in the vicinity of the conveyance start position 103a. The structure and operation of the stopper 114 will be described later.
  • a transportation control unit 116 mounted on a circuit board is provided on the side of the base 118.
  • the transport control unit 116 controls the operation of the handlers 104 and 106.
  • the first sensor 110 and the second sensor 112 are connected to the transport control unit 116 by wiring, and their detection signals are taken into the transport control unit 116.
  • the transport control unit 116 is configured to start the transport operation of the sample rack based on the detection signal when the first sensor 110 detects the arrival of the sample rack.
  • the transport control unit 116 is connected to an arithmetic control device 34 which will be described later with reference to FIG. 11, and detection signals of the first sensor 110 and the second sensor 112 are also taken into the arithmetic control device 34. Yes.
  • the transport state of the sample rack in the sample transport device 12 is managed by the calculation control device 34.
  • FIGS. 2 and 4 illustration of the modules mounted on the wiring and transport control unit 116 is omitted.
  • FIG. 3 some of the modules mounted on the transport control unit 116 are illustrated, but illustration of wiring is omitted.
  • the stopper 114 is a member refracted at a substantially right angle on the way.
  • the base end portion of the stopper 114 is held by a holding member 126 provided below the table 102 and below the end portion on the conveyance start position 103a side, and the distal end portion faces the conveyance start position 103a side.
  • the tip of the stopper 114 extends over the end of the conveying mechanism of the roller 140 of the belt conveyor 7a onto the belt conveyor 7a, and stops the sample rack 20 on the belt conveyor 7a.
  • the holding member 126 holding the base end of the stopper 114 can be moved in the vertical direction, so that the stopper 114 also moves up and down, and the sample rack 20 is stopped and released depending on the height of the stopper 114.
  • the stopper 114 stops the sample rack 20 in a state where the tip end is lifted above the table 102 (state shown in FIG. 8A), and the tip end is lowered to the same height as the table 102 or below the table 102 ( The state of the sample rack 20 is released in the state of FIG. 8B.
  • a fixed shaft 130 extending in the Y direction is attached to the base 118 side (see FIG. 6), and the holding member 126 and the fixed shaft 130 are connected by a spring 128.
  • the spring 128 connects the holding member 126 and the fixed shaft 130 in a state of extending beyond the natural length so as to apply an elastic force in the direction in which the holding member 126 is raised.
  • a sliding portion 142 that moves horizontally in the X direction in conjunction with the handlers 104 and 106 is provided.
  • the sliding portion 142 is a shaft or protrusion having a circular cross section.
  • One end of the interlocking member 127 is connected to the side portion of the holding member 126.
  • the interlocking member 127 extends in the transport direction (X direction) of the sample rack 20 by the handlers 104 and 106, and the upper surface 127 a is always in contact with the sliding portion 142.
  • the upper surface 127a of the interlocking member 127 has a straight portion and a smooth slope portion that rises toward the holding member 126 side, and the upper surface 127a of the interlocking member 127 follows the horizontal movement of the sliding portion 142.
  • the holding member 126 moves up and down.
  • the stopper 114 When the holding portion (protrusions 104a and 106a) on the handler transfer start position 103a is closer to the transport completion position 103b than the transfer start position 103a, the stopper 114 is lifted above the table 102 (the state shown in FIG. 8A). ), And the stopper 114 is lowered to the same height as the table 102 or below the table 102 when the holding portions (projections 104a and 106a) on the transport start position 103a side of the handler come to the transport start position (see FIG. 8B). The shape of the upper surface 127a of the interlocking member 127 is adjusted so as to be in the state).
  • the handlers 104 and 106 move to the belt conveyor 7b side (left side in the figure) while holding the sample rack 20 (FIG. 9D), and release the sample rack 20 at a position on the table 102 (temporary placement unit) ( FIG. 10 (E)). While the sample rack 20 is placed on the table 102, only the handlers 104 and 106 move to the front conveyor 7a side (right side in the figure) (FIG. 10F), and the sample racks are moved by the second holders 104b and 106b. 20 is held (FIG. 10G). While holding the sample rack 20 by the second holding units 104b and 106b, the sample rack 20 is moved to the rear conveyor 7b side (left side in the figure), and the sample rack 20 is placed on the rear conveyor 7b (FIG. 10H). .
  • the front-side automatic analyzer 2a is provided with a control unit 32a that controls the operation of the collection and analysis unit 4a, the transport unit 6a, and the sample introduction mechanism 18a.
  • the rear-side automatic analyzer 2b includes the collection and analysis unit 4b, the transport unit 6b, and A control unit 32b that controls the operation of the sample introduction mechanism 18b is provided.
  • the sample transport device 12 is provided with a transport control unit 116 that controls the operation of the transport mechanism 100.
  • the control units 32a, 32b, and 116 are connected to the arithmetic control device 34, respectively.
  • an item information holding unit 39 that holds information (analysis item information) related to analysis items to be executed on the specimen, and an analysis item designated by the operator is sent to the front-side automatic analyzer 2a or the rear-side automatic
  • An analysis operation execution means 35 is provided for transmitting a control signal based on the analysis item information held in the item information holding unit to the control unit 32a or 32b so as to be executed in the analysis device 2b.
  • the analysis item information includes information such as the type of reagent added to the specimen, the amount of reagent, and whether or not stirring is performed.
  • a predetermined amount of reagent used for the analysis item is collected from the analysis item information and reagent information in the reagent information storage unit 41 described later, and added to the sample. It has become.
  • the measurement data obtained by the sampling analysis unit 4a of the upstream automatic analyzer 2a is taken into the arithmetic control device 34 via the control unit 32a, and the measurement data obtained by the sampling analysis unit 4b of the downstream automatic analyzer 2b is The data is taken into the arithmetic and control unit 34 through the control unit 32b.
  • the arithmetic and control unit 34 has a function of identifying and quantifying the components in the specimen using the taken measurement data.
  • the control units 32a and 32b and the transport control unit 116 are realized by dedicated computers of the respective devices.
  • the arithmetic and control unit 34 is realized by, for example, a general-purpose personal computer (PC) or a dedicated computer.
  • An information display unit 42 is connected to the calculation control device 34, and information such as calculation results made by the calculation control device 34 is displayed on the information display unit 42.
  • the information display unit 42 is realized by, for example, a general-purpose PC monitor or a dedicated monitor. Detection signals of the first sensor 110 and the second sensor 112 are taken into the arithmetic control device 34 via the transport control unit 116.
  • the arithmetic and control unit 34 is further provided with a rule violation determination unit 36, an information display unit 37, a rule violation display unit 38, a rule holding unit 40, and a reagent information storage unit 41.
  • a case will be described in which the information reader 33a is provided in the upstream automatic analyzer 2a and the information reader 33b is provided in the downstream automatic analyzer 2b.
  • the information readers 33a and 33b are, for example, barcode readers, which read information from information media such as barcodes attached to reagent containers installed in the reagent installation units 22a and 22b of the collection analysis units 4a and 4b. .
  • the reagent information read by the information readers 33a and 33b is taken into the arithmetic and control unit 34 via the control units 32a and 32b and stored in the reagent information storage unit 41.
  • the information display means 37 is configured to display a list of reagent information read by the information readers 33a and 33b on the information display unit 42 as a reagent information list in addition to the calculation result in the calculation control device 34.
  • the rule violation determining means 36 is configured to determine whether or not the installation of the reagent violates a predetermined rule based on the reagent information read by the information readers 33a and 33b.
  • the following rules (1) and (2) are established for the installation of reagent containers in the reagent installation sections 22a and 22b of the respective automatic analyzers 2a and 2b. These rules (1) and (2) are held in the rule holding unit 40.
  • All reagents used for one analysis item are installed in one automatic analyzer.
  • the same type of reagent should not be installed in the two automatic analyzers.
  • the rule violation display unit 38 displays reagent information displayed on the information display unit 42 when the reagent violation violates any of the rules (1) and (2) as a result of the determination by the rule violation determination unit 36.
  • the display of reagent information that violates the rules in the list is configured to allow the operator to recognize that the arrangement of the reagents violates the rules. Yes.
  • an analysis item that uses a reagent that violates the rule is automatically selected. Since it cannot be completed by the analyzer, the arithmetic and control unit 34 prohibits the operator from specifying the analysis item.
  • the automatic analyzer with the higher priority for example, the reagent was installed first
  • the analysis item is executed only by the other automatic analyzer, etc., and the fact that the reagent of the other automatic analyzer is violated is displayed.
  • FIG. 13 shows an example of the display screen of the reagent information list. Since the reagent indicated in the third column from the top in the list on the lower right of the display screen violates the rule, the installation position of this reagent is shown. The number (Position.) “1” is displayed in red (other reagents are displayed in black).
  • the rule violation determining means 36 determines whether or not the inputted reagent information violates the above rule.
  • the operator can individually manage the operations of the devices 2a, 2b and 116 via the arithmetic and control unit 34.
  • the operator individually manages the operations of the front-side automatic analyzer 2a, the rear-side automatic analyzer 2b, and the sample transport device 12 through the arithmetic and control unit 34, so that the front-side automatic analyzer 2a and the rear-side automatic analyzer 2b.
  • the sample can be analyzed with only one apparatus. As a result, even if a problem occurs in one of the automatic analyzers and the sample transport apparatus 12, the sample can be analyzed using an automatic analyzer that is free of defects.
  • the rule violation determination means 36 confirms the rule that the installation of the reagent container is held in the rule holding unit 40 and determines whether or not the rule is violated.
  • the reagent information input by the operator is stored in the reagent information storage unit 41, and the rule violation determining means 36 is based on the reagent information. It is determined whether or not the reagent container installation violates the rules of the rule holding unit 40.
  • the related item information of the reagent is acquired, and the reagent information is normally displayed in the reagent information list displayed on the information display unit 42 by the information display unit 37, and The reagent information list is updated and stored in the reagent information storage unit 41.
  • a warning to that effect is displayed on the information display unit 42, and a part of the reagent information (for example, reagent holder number) is different from other reagent information.
  • the color information (for example, red) is displayed on the reagent information list, and the reagent information list is updated and stored in the reagent information storage unit 41. The above operation is repeated when the reagent container is installed.

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Abstract

An automatic analysis system is provided with a plurality of automatic analysis devices, sample transport devices that are disposed between adjacent automatic analysis devices from among the plurality of automatic analysis devices so as to link the adjacent automatic analysis devices, and a calculation control device that is connected to all the automatic analysis devices and sample transport devices and manages the overall operation of the automatic analysis system. The calculation control device retains a rule indicating that all reagents used for a single analysis item must be placed in a single automatic analysis device, and if a reagent placed in a reagent placement unit is in violation of this rule, the calculation control device indicates this using a method that is recognizable by an operator.

Description

複数の分析装置を連結してなる自動分析システムAutomatic analysis system connecting multiple analyzers
　本発明は、複数の分析装置を連結して構成された自動分析システムに関するものである。 The present invention relates to an automatic analysis system configured by connecting a plurality of analyzers.
　自動分析装置は、容器に収容された検体を自動的にサンプリングして分析を行なうように構成されている。かかる自動分析装置は、検体を搬送する機構として、複数の検体容器を保持した検体ラックを載置して搬送するベルトコンベアと、ベルトコンベアによって所定位置まで搬送された検体ラックをベルトコンベアから取り出して所定のサンプリング位置へ搬送するアームなどの機構を備えている（例えば、特許文献１参照。）。 The automatic analyzer is configured to automatically sample and analyze the sample contained in the container. In such an automatic analyzer, as a mechanism for transporting a sample, a belt conveyor for mounting and transporting a sample rack holding a plurality of sample containers, and a sample rack transported to a predetermined position by the belt conveyor are taken out from the belt conveyor. A mechanism such as an arm that transports the sample to a predetermined sampling position is provided (for example, see Patent Document 1).
　かかる自動分析装置では、ベルトコンベアの始端側にオペレータが検体ラックを設置するための設置部が設けられ、終端側にサンプリングの終了した検体ラックを回収するための検体ラック回収部が設けられている。オペレータが設置部に検体ラックを設置すると、その検体ラックがベルトコンベアによって搬送され、所定の位置でアームにより別のサンプリング位置に搬送されて検体容器に対するサンプリングが行なわれる。サンプリングの終了した検体ラックはアームによって再びベルトコンベア上に戻され、ベルトコンベアによって終端側の検体ラック回収部まで搬送されて回収される。 In such an automatic analyzer, an installation unit for an operator to install a sample rack is provided on the start side of the belt conveyor, and a sample rack collection unit for collecting the sample rack after sampling is provided on the end side. . When the operator installs the sample rack in the installation unit, the sample rack is transported by the belt conveyor, and is transported to another sampling position by the arm at a predetermined position to perform sampling on the sample container. The sample rack that has been sampled is returned again onto the belt conveyor by the arm, and is transported to the sample rack recovery section on the terminal side by the belt conveyor and collected.
特開２０１１－１８５８９３号公報JP 2011-185893 A
　上記のような自動分析装置でサンプリングの終了した検体容器を別の自動分析装置でもサンプリングさせて分析したい場合、従来は、オペレータが自動分析装置の回収部から検体ラックを取り出し、別の自動分析装置の設置部に設置する必要があり、自動分析装置でサンプリングの終了した検体を自動的に別の自動分析装置へ導入するようなシステムは構築されていなかった。 When a sample container that has been sampled by an automatic analyzer as described above is to be sampled and analyzed by another automatic analyzer, conventionally, the operator takes out the sample rack from the collection unit of the automatic analyzer, and another automatic analyzer. Therefore, a system that automatically introduces a sample that has been sampled by an automatic analyzer into another automatic analyzer has not been constructed.
　そこで、本発明は、複数の自動分析装置に共通の検体容器を自動的に順次導入して分析することのできる自動分析システムを提供することを目的とするものである。 Therefore, an object of the present invention is to provide an automatic analysis system capable of automatically introducing and analyzing common sample containers sequentially in a plurality of automatic analyzers.
　本発明にかかる自動分析システムは、複数の自動分析装置、それらの自動分析装置のうち隣接する自動分析装置の間に配置されて隣接する自動分析装置を連結する検体輸送装置、及び自動分析装置と検体輸送装置のすべてに接続されて該自動分析システム全体の動作管理を行なう演算制御装置を備えたものである。自動分析装置の各々は、検体容器を保持した検体ラックを搬送するベルトコンベア、複数の試薬を設置する試薬設置部、検体容器から検体を採取するとともに試薬設置部の試薬をその検体に添加して反応させて分析を行なう採取分析部及びベルトコンベア上の検体ラックを保持して採取分析部へ導入する検体導入機構をそれぞれ独自に備えている。検体輸送装置は、互いに隣接する自動分析装置のうち一方のベルトコンベアの終端で検体ラックを保持して他方のベルトコンベアの始端まで搬送する搬送機構を備えたものである。 An automatic analysis system according to the present invention includes a plurality of automatic analyzers, a sample transport device that is arranged between adjacent automatic analyzers among the automatic analyzers and connects adjacent automatic analyzers, and an automatic analyzer It is provided with an arithmetic and control unit that is connected to all of the sample transport devices and manages the operation of the entire automatic analysis system. Each of the automatic analyzers includes a belt conveyor that transports a sample rack that holds a sample container, a reagent installing unit that installs a plurality of reagents, a sample is collected from the sample container, and a reagent in the reagent installing unit is added to the sample. A sampling analysis unit that performs analysis by reaction and a sample introduction mechanism that holds the sample rack on the belt conveyor and introduces the sample rack to the sampling analysis unit are provided. The sample transport device includes a transport mechanism that holds a sample rack at the end of one belt conveyor among the automatic analyzers adjacent to each other and transports the sample rack to the start end of the other belt conveyor.
　さらに、本発明の自動分析システムは、各自動分析装置の試薬設置部に設置されている試薬の情報を取得する試薬情報取得手段を備え、演算制御装置は、いずれかの自動分析装置において実行されうる分析項目で使用される試薬の情報を保持する項目情報保持部、各自動分析装置の試薬設置部に設置される試薬についての規則の一つとして、１つの分析項目で使用されるすべての試薬が１つの自動分析装置に設置されていなければならないという規則を保持する規則保持部、各自動分析装置の試薬設置部に設置されている試薬が規則に反するか否かを判定する規則違反判定手段、及び試薬設置部に設置されている試薬が規則に反する場合に、その旨をオペレータの認識しうる方法で表示するように構成されている規則違反表示手段を備えている。 Furthermore, the automatic analysis system of the present invention includes reagent information acquisition means for acquiring information on the reagents installed in the reagent installation section of each automatic analyzer, and the arithmetic and control unit is executed in any of the automatic analyzers. All the reagents used in one analysis item as one of the rules for the reagents installed in the reagent installation section of each automatic analyzer, the item information holding section that holds the information of the reagents used in the possible analysis items A rule holding unit that holds a rule that must be installed in one automatic analyzer, and a rule violation determination unit that determines whether or not a reagent installed in a reagent installation unit of each automatic analyzer violates the rule And a rule violation display means configured to display in a manner that can be recognized by the operator when the reagent installed in the reagent installing unit violates the rules. That.
　本発明では、演算制御装置が、検体に対して実行すべき分析項目として指定された分析項目のそれぞれについて、試薬情報取得手段によって各自動分析装置に設置されている試薬を確認し、指定の分析項目で使用する試薬のすべてが設置されている自動分析装置をその分析項目を実行する自動分析装置として選択するように構成された項目実行装置選択手段をさらに備えていることが好ましい。そうすれば、オペレータが分析項目を指定するだけでその分析項目を実行する自動分析装置が自動的に選択されるので、オペレータが各自動分析装置に設置されている試薬の種類を確認してその分析項目を実行させる自動分析装置を選択する必要がない。 In the present invention, the arithmetic and control unit confirms the reagent installed in each automatic analyzer by the reagent information acquisition means for each analysis item specified as the analysis item to be executed on the sample, and performs the specified analysis. It is preferable that the apparatus further includes an item execution device selection means configured to select an automatic analyzer in which all of the reagents used in the items are installed as an automatic analyzer that executes the analysis item. Then, the operator automatically selects the automatic analyzer that executes the analysis item simply by specifying the analysis item, so the operator checks the type of reagent installed in each automatic analyzer and There is no need to select an automatic analyzer for executing the analysis item.
　上記の場合、同じ種類の試薬が異なる自動分析装置に設置されていると、オペレータによって分析項目が指定されたときに、その分析項目を実行可能な自動分析装置が複数存在することがある。しかし、複数の自動分析装置において同じ分析項目を実行可能にすると、並行して実行することのできる分析項目数が少なくなってしまう。また、装置の構成上、仮に同じ項目を複数の分析装置で分析できるように試薬をセットしても、同じラックにセットした検体に依頼する項目の内容によっては、システムの動作が非効率になる場合がある。これに対し、同じ試薬は、同じ自動分析装置に設置することにより、各分析項目はいずれか１つの分析装置で請け負うことになり、オペレータがシステムの一連の動作を予測しやすくなり、項目の振り分け方を工夫する、あるいは検体をラックにセットするときに依頼する項目が類似した検体を同じラックにセットするようにする、などといった対応を行うことができるので、効率的に各検体について各分析項目を実行することができるようになる。 In the above case, if the same type of reagent is installed in different automatic analyzers, there may be a plurality of automatic analyzers that can execute the analysis item when the analysis item is specified by the operator. However, if the same analysis item can be executed in a plurality of automatic analyzers, the number of analysis items that can be executed in parallel decreases. In addition, due to the configuration of the apparatus, even if the reagent is set so that the same item can be analyzed by a plurality of analyzers, the operation of the system becomes inefficient depending on the content of the item requested for the sample set in the same rack. There is a case. On the other hand, if the same reagent is installed in the same automatic analyzer, each analysis item will be undertaken by one of the analyzers, making it easier for the operator to predict the series of operations of the system and sorting the items. The analysis items can be efficiently analyzed for each sample because it is possible to devise a method or to set samples with similar items requested when setting the sample in the rack. Will be able to run.
　そこで、本発明においては、規則保持部は、同じ種類の試薬の試薬容器が異なる自動分析装置の試薬設置部に設置されてはならないという規則も保持していることが好ましい。そうすれば、複数の自動分析装置において同じ分析項目が実行できるような状況となったときにオペレータに注意が促され、そのような状況を回避することができる。 Therefore, in the present invention, it is preferable that the rule holding unit also holds a rule that reagent containers of the same type of reagent should not be installed in reagent installing units of different automatic analyzers. If it does so, when it will be in the situation where the same analysis item can be performed in several automatic analyzers, an operator will be alerted and such a situation can be avoided.
　好ましい実施態様の一例として、演算制御装置に接続され、情報を表示する情報表示部をさらに備え、演算制御装置は、各自動分析装置の試薬設置部に設置されている試薬容器の情報の一覧を情報表示部に表示するように構成された情報表示手段をさらに備え、規則違反表示手段は、情報表示手段により情報表示部に表示された試薬容器の情報の一覧のうち規則に違反している試薬容器の情報の一部分を他の試薬容器の情報の同じ部分とは異なる色で表示するように構成されている例を挙げることができる。 As an example of a preferred embodiment, the information processing unit further includes an information display unit that is connected to the arithmetic control device and displays information, and the arithmetic control device displays a list of information on the reagent containers installed in the reagent installing unit of each automatic analyzer. An information display unit configured to display on the information display unit is further provided, and the rule violation display unit is a reagent that violates the rule in the list of information on the reagent container displayed on the information display unit by the information display unit. An example may be given in which a part of the container information is displayed in a different color from the same part of the information of the other reagent containers.
　試薬情報取得手段の一形態は、各試薬容器に添付されその試薬容器に関する情報を記録した情報媒体、及び試薬設置部に設置される試薬容器の情報媒体から情報を読み取る情報読取器によって構成されるものである。 One form of the reagent information acquisition means is configured by an information medium attached to each reagent container and recording information on the reagent container, and an information reader that reads information from the information medium of the reagent container installed in the reagent installing unit. Is.
　情報媒体の一例としてバーコードが挙げられ、その場合の情報読取器はバーコードリーダーである。 An example of the information medium is a barcode, and the information reader in that case is a barcode reader.
　また、試薬情報取得手段の他の形態は、試薬設置部に設置された試薬容器についての情報をオペレータに入力させ、入力された情報を記憶するように構成されたものであってもよい。 Further, another form of the reagent information acquisition means may be configured to allow an operator to input information about the reagent container installed in the reagent installation unit and to store the input information.
　本発明の自動分析システムは、複数の自動分析装置が検体輸送装置によって連結されて構成され、互いに隣接する自動分析装置のうち一方のベルトコンベアの終端まで到達した検体ラックが検体輸送装置によって後段側の自動分析装置のベルトコンベアの始端まで自動的に搬送されるようになっているので、互いに独立した自動分析装置として成立する複数の自動分析装置に共通の検体を自動的に導入して分析することができる。 The automatic analysis system of the present invention includes a plurality of automatic analyzers connected by a sample transport device, and a sample rack that has reached the end of one belt conveyor among the adjacent automatic analyzers is connected to the rear stage side by the sample transport device. Because it is automatically transported to the beginning of the belt conveyor of the automatic analyzer, a common sample is automatically introduced and analyzed in a plurality of automatic analyzers that are established as independent automatic analyzers. be able to.
　この自動分析システムでは、隣接して配置された自動分析装置に個別に設けられているベルトコンベアを検体輸送装置によって連結することで、複数の自動分析装置に共通の検体を導入することができるようにしているので、全ての自動分析装置間を横断するような大掛かりなベルトコンベアなどの搬送装置を設ける必要がない。かかる構成により、前段側の自動分析装置で分析の終了した検体を後段側の自動分析装置へ移行させて新たな分析を実行することはできるが、前段側の自動分析装置と後段側の自動分析装置との間で検体を自由に行き来させることはできない。そのため、ある分析項目について複数の試薬を用いる場合に、それらの試薬が別々の自動分析装置に配置されていると、検体を複数の自動分析装置内で自由に行き来させることができないために、その分析項目を完結させることができないということが起こりうる。 In this automatic analysis system, a common sample can be introduced into a plurality of automatic analyzers by connecting belt conveyors individually provided to adjacent automatic analyzers by a sample transport device. Therefore, it is not necessary to provide a transport device such as a large belt conveyor that traverses all automatic analyzers. With this configuration, it is possible to transfer a sample that has been analyzed by the first-stage automatic analyzer to the second-stage automatic analyzer and perform a new analysis. However, the first-stage automatic analyzer and the second-stage automatic analyzer The specimen cannot be freely moved back and forth between the devices. Therefore, when using multiple reagents for a certain analysis item, if those reagents are placed in different automatic analyzers, the specimen cannot be freely moved back and forth within the multiple automatic analyzers. It can happen that the analysis item cannot be completed.
　そこで、本発明の自動分析システムでは、各分析項目が必ず１つの自動分析装置で完結するように、各自動分析装置の試薬設置部に設置される試薬容器についての規則の一つとして、１つの分析項目で使用されるすべての試薬の試薬容器が１つの自動分析装置の試薬設置部に設置されていなければならないという規則を設け、その規則を規則保持部に保持させている。そして、演算制御装置に、各自動分析装置の試薬設置部に設置されている試薬容器が規則に反するか否かを判定する規則違反判定手段、及び試薬設置部に設置されている試薬容器が規則に反する場合に、その旨をオペレータの認識しうる方法で表示するように構成されている規則違反表示手段を設けている。これにより、試薬容器の設置場所が正しいか否かをオペレータが認識しやすくなり、同一の分析項目で使用される試薬が別々の自動分析装置に設置されることが予防される。 Therefore, in the automatic analysis system of the present invention, as one of the rules for the reagent container installed in the reagent installation section of each automatic analyzer, one analysis item is always completed by one automatic analyzer. There is a rule that the reagent containers of all the reagents used in the analysis item must be installed in the reagent installing unit of one automatic analyzer, and the rule is held in the rule holding unit. Then, in the arithmetic and control unit, rule violation determining means for determining whether or not the reagent container installed in the reagent installing unit of each automatic analyzer is against the rules, and the reagent container installed in the reagent installing unit are in accordance with the rules. If it is contrary to the above, there is provided a rule violation display means configured to display that fact by a method that can be recognized by the operator. This makes it easier for the operator to recognize whether the installation location of the reagent container is correct, and prevents reagents used for the same analysis item from being installed in different automatic analyzers.
自動分析システムの一実施例を示す斜視図である。It is a perspective view which shows one Example of an automatic analysis system. 同実施例の構成を示す概略平面図であるIt is a schematic plan view which shows the structure of the Example. 同実施例における検体輸送装置の斜視図である。It is a perspective view of the sample transport apparatus in the same Example. 同検体輸送装置の搬送機構の一例を示す平面図である。It is a top view which shows an example of the conveyance mechanism of the sample transport apparatus. 同搬送機構の側面図である。It is a side view of the transport mechanism. 同搬送機構の斜め上方向から見た分解斜視図である。It is the disassembled perspective view seen from diagonally upward direction of the conveyance mechanism. 同搬送機構の斜め下方向から見た分解斜視図である。It is the disassembled perspective view seen from the diagonally downward direction of the conveyance mechanism. 及びas well as 同搬送機構のストッパの構造を説明するための概念図である。It is a conceptual diagram for demonstrating the structure of the stopper of the conveyance mechanism. 同搬送機構の動作を順に示す平面図である。It is a top view which shows operation | movement of the conveyance mechanism in order. 同検体輸送装置の動作の続きを示す平面図である。It is a top view which shows the continuation of operation | movement of the sample transport apparatus. 同実施例の制御系統を概略的に示すブロック図である。It is a block diagram which shows roughly the control system of the Example. 試薬容器を設置する際の試薬情報の入力とその表示の流れの一例について示すフローチャートである。It is a flowchart shown about an example of the input of the reagent information at the time of installing a reagent container, and the flow of the display. 試薬情報リストの表示画面の一例を示す画像である。・・補充願いますIt is an image which shows an example of the display screen of a reagent information list. ..Please replenish
　図１及び図２を用いて自動分析システムの一実施例について説明する。 An embodiment of the automatic analysis system will be described with reference to FIGS.
　この自動分析システム１は、２つの自動分析装置２ａ，２ｂと検体輸送装置１２、これらの装置２ａ，２ｂ，１２に接続された演算制御装置３４（図１１参照）により構成されている。自動分析装置２ａ，２ｂは水平面内の一方向であるＸ方向に並んで配置され、両自動分析装置２ａ，２ｂのそれぞれの搬送部６ａと６ｂの間が検体輸送装置１２によって連結されている。この自動分析システム１では、前段側の自動分析装置２ａにおいてサンプリングの終了した検体が検体輸送装置１２を介して後段側の自動分析装置２ｂに導入され、後段側の自動分析装置２ｂにおいてもその検体のサンプリングと分析がなされる。演算制御装置３４については後述する。 The automatic analysis system 1 includes two automatic analyzers 2a and 2b, a sample transport device 12, and an arithmetic control device 34 (see FIG. 11) connected to these devices 2a, 2b and 12. The automatic analyzers 2a and 2b are arranged side by side in the X direction, which is one direction in the horizontal plane, and the transport parts 6a and 6b of both the automatic analyzers 2a and 2b are connected by the sample transport device 12. In this automatic analysis system 1, a sample that has been sampled in the front-stage automatic analyzer 2a is introduced into the rear-stage automatic analyzer 2b via the sample transport device 12, and the sample is also received in the rear-stage automatic analyzer 2b. Sampling and analysis. The arithmetic control device 34 will be described later.
　前段側の自動分析装置２ａは、採取分析部４ａ、搬送部６ａ及び検体導入機構１８ａを備えている。搬送部６ａは検体容器を保持した検体ラック２０をＸ方向の一方側（図１及び図２において左側）へ搬送するベルトコンベア７ａ（前段側コンベア）を備えている。ベルトコンベア７ａの周囲はカバーで覆われている。搬送部６ａの始端側（図１及び図２において右側）に検体ラック配置部８ａが設けられ、終端側（同図において左側）に検体ラック回収部１０ａが設けられている。検体ラック配置部８ａと検体ラック回収部１０ａのカバーは開閉可能であり、オペレータが検体ラック配置部８ａのカバーを開けて検体ラックをベルトコンベア７ａ上に配置したり、検体ラック回収部１０ａのカバーを開けてサンプリングの終了した検体ラックを取り出したりすることができる。 The front-stage automatic analyzer 2a includes a collection analysis unit 4a, a transport unit 6a, and a sample introduction mechanism 18a. The transport unit 6a includes a belt conveyor 7a (a front-stage conveyor) that transports the sample rack 20 holding the sample containers to one side in the X direction (left side in FIGS. 1 and 2). The periphery of the belt conveyor 7a is covered with a cover. A sample rack arrangement unit 8a is provided on the start end side (right side in FIGS. 1 and 2) of the transport unit 6a, and a sample rack collection unit 10a is provided on the end side (left side in FIG. 1). The covers of the sample rack arranging unit 8a and the sample rack collecting unit 10a can be opened and closed. An operator opens the cover of the sample rack arranging unit 8a and arranges the sample rack on the belt conveyor 7a, or covers the sample rack collecting unit 10a. The sample rack that has been sampled can be taken out by opening.
　検体導入機構１８ａは水平面内においてＸ方向と直交するＹ方向へ移動し、ベルトコンベア７ａ上の検体ラック２０を保持して採取分析部４ａ側へ導入したり、サンプリングの終了した検体ラック２０をベルトコンベア７ａ上に戻して配置したりするものである。搬送部６ａの検体ラック配置部８ａと検体ラック回収部１０ａの間に検体ラック導入部９ａが設けられており、検体導入機構１８ａは検体ラック導入部９ａからベルトコンベア７ａ上のサンプリング前の検体ラック２０を採取分析部４ａ内に移送したり，サンプリング後の検体ラック２０をベルトコンベア７ａ上に戻したりするようになっている。 The sample introduction mechanism 18a moves in the Y direction perpendicular to the X direction in the horizontal plane, holds the sample rack 20 on the belt conveyor 7a and introduces it to the collection analysis unit 4a side, or the sample rack 20 that has been sampled is belted. It is placed back on the conveyor 7a. A sample rack introduction section 9a is provided between the sample rack placement section 8a and the sample rack collection section 10a of the transport section 6a, and the sample introduction mechanism 18a is provided with a sample rack before sampling on the belt conveyor 7a from the sample rack introduction section 9a. 20 is transferred into the collection analysis unit 4a, and the sample rack 20 after sampling is returned to the belt conveyor 7a.
　採取分析部４ａは、検体導入機構１８ａにより移送された検体容器から検体を採取するための吸入プローブなどを有する検体採取機構（図示は省略）のほか、試薬設置部２２ａ、検体ラック収容部２４ａ及び測定部２６ａを備えている。検体ラック収容部２４ａには、検体導入機構１８ａによってベルトコンベア７ａ上から移送された検体ラック２０が複数収容される。検体ラック収容部２４ａはターンテーブルになっていて、検体ラック２０上の検体容器を、吸入プローブが検体を採取するときの所定位置に配置する。 In addition to a sample collection mechanism (not shown) having an inhalation probe for collecting a sample from the sample container transferred by the sample introduction mechanism 18a, the collection analysis unit 4a includes a reagent installation unit 22a, a sample rack storage unit 24a, A measurement unit 26a is provided. A plurality of sample racks 20 transferred from the belt conveyor 7a by the sample introduction mechanism 18a are accommodated in the sample rack accommodating portion 24a. The sample rack accommodating portion 24a is a turntable, and the sample container on the sample rack 20 is arranged at a predetermined position when the inhalation probe collects the sample.
　試薬設置部２２ａには、試薬を収容した試薬容器を設置するための複数の試薬ホルダー２３ａが設けられている。試薬設置部２２ａの各試薬ホルダー２３ａに設置される試薬容器の試薬情報は、オペレータが演算制御装置３４（図１１参照）に設置した試薬容器の試薬情報を入力することで、又は、各試薬容器に添付された情報媒体としてのバーコードの情報が情報読取器としてのバーコードリーダーによって読み取られることで、演算制御装置３４に入力され、どの試薬ホルダー２３ａにどのような試薬が収容されているかが演算制御装置３４に登録されるようになっている。オペレータが手動で試薬情報を入力するようになっている場合には演算制御装置３４が試薬情報取得手段を兼ねており、バーコードの情報をバーコードリーダーによって読み取るようになっている場合にはバーコード及びバーコードリーダーが試薬情報取得手段を実現している。後述するが、演算制御装置３４は、試薬設置部２２ａのどの試薬ホルダー２３ａにどのような試薬が収容されているかを一覧で示す試薬情報リストを作成して情報表示部４２（図１１参照）に表示する機能をもち、オペレータはこれを参照することができる。 The reagent installing section 22a is provided with a plurality of reagent holders 23a for installing a reagent container containing a reagent. The reagent information of the reagent container installed in each reagent holder 23a of the reagent installing unit 22a is input by the operator inputting the reagent information of the reagent container installed in the arithmetic control device 34 (see FIG. 11), or each reagent container The barcode information as the information medium attached to the information reader is read by the barcode reader as the information reader, so that it is input to the arithmetic and control unit 34 and what reagent is stored in which reagent holder 23a. It is registered in the arithmetic and control unit 34. When the operator manually inputs reagent information, the arithmetic and control unit 34 also serves as reagent information acquisition means. When the bar code information is read by the bar code reader, the bar code reader is used. The code and barcode reader realize reagent information acquisition means. As will be described later, the arithmetic and control unit 34 creates a reagent information list indicating which reagents are stored in which reagent holders 23a of the reagent installing unit 22a and displays them in the information display unit 42 (see FIG. 11). It has a display function and can be referred to by the operator.
　測定部２６ａには、吸入プローブによって採取された検体と試薬を混合する容器が複数個設けられており、容器内の反応を光学的に測定するように構成されている。かかる構成により、採取分析部４ａでは、検体ラック２０が検体導入機構１８ａによって検体ラック収容部２４ａに収容され、その検体ラック２０に保持されている検体容器が所定位置に配置され、吸入プローブによって検体が採取される。採取された検体は測定部２６ａに設けられた容器に注入され、分析項目に応じた試薬が吸入プローブによって添加された後、検体と試薬の反応が吸光度や蛍光強度など光学的に測定される。 The measurement unit 26a is provided with a plurality of containers for mixing the sample and reagent collected by the inhalation probe, and is configured to optically measure the reaction in the container. With this configuration, in the collection analysis unit 4a, the sample rack 20 is stored in the sample rack storage unit 24a by the sample introduction mechanism 18a, the sample container held in the sample rack 20 is disposed at a predetermined position, and the sample is collected by the inhalation probe. Is collected. The collected specimen is injected into a container provided in the measurement unit 26a, and after a reagent corresponding to the analysis item is added by an inhalation probe, the reaction between the specimen and the reagent is optically measured such as absorbance and fluorescence intensity.
　後段側の自動分析装置２ｂは前段側の自動分析装置２ａと同じ構成を有する。自動分析装置２ｂの搬送部６ｂに設けられたベルトコンベア７ｂ（後段側コンベア）の始端と前段側のベルトコンベア７ａの終端とは検体輸送装置１２によって連結されている。 The latter-stage automatic analyzer 2b has the same configuration as the former-stage automatic analyzer 2a. The starting end of the belt conveyor 7b (rear side conveyor) provided in the transport unit 6b of the automatic analyzer 2b and the end of the front belt conveyor 7a are connected by the sample transport device 12.
　検体輸送装置１２は、前段側のベルトコンベア７ａの終端にきた検体ラック２０を保持して後段側のベルトコンベア７ｂの始端に配置する搬送機構とその搬送機構を覆う開閉式の遮蔽カバー１４を備えている。搬送機構については後述する。図３に示されているように、検体輸送装置１２の筐体の遮蔽カバー１４の開閉部分にマイクロスイッチ３０が設けられている。マイクロスイッチ３０は遮蔽カバー１４側に設けられたピン２８と接触することによってオン／オフが切り換えられるものである。遮蔽カバー１４が閉じられるとピン２８がマイクロスイッチ３０をオンの状態にし、遮蔽カバー１４が開かれるとマイクロスイッチ３０がオフの状態となる。検体輸送装置１２の搬送機構は遮蔽カバー１４が閉じられてマイクロスイッチ３０がオンになっているときにのみ動作し、遮蔽カバー１４が開かれてマイクロスイッチ３０がオフになっているときはその動作を停止するようになっている。 The sample transport device 12 includes a transport mechanism that holds the sample rack 20 that comes to the end of the front-side belt conveyor 7a and is disposed at the start end of the rear-side belt conveyor 7b, and an openable / closable shielding cover 14 that covers the transport mechanism. ing. The transport mechanism will be described later. As shown in FIG. 3, a micro switch 30 is provided at an opening / closing portion of the shielding cover 14 of the housing of the sample transporting device 12. The microswitch 30 is switched on / off by contacting a pin 28 provided on the shielding cover 14 side. When the shielding cover 14 is closed, the pin 28 turns the microswitch 30 on, and when the shielding cover 14 is opened, the microswitch 30 is turned off. The transport mechanism of the sample transport apparatus 12 operates only when the shielding cover 14 is closed and the microswitch 30 is turned on, and operates when the shielding cover 14 is opened and the microswitch 30 is turned off. Is supposed to stop.
　検体輸送装置１２の搬送機構の一例について図４から図７を用いて説明する。 An example of the transport mechanism of the sample transport device 12 will be described with reference to FIGS.
　搬送機構１００は水平面を有するテーブル１０２を備えている。テーブル１０２は基台１１８によって支持されている。テーブル１０２の水平面は両端に配置されるベルトコンベア７ａ，７ｂの搬送面とほぼ同じ高さに設定されている。テーブル１０２のＸ方向における一方側（図において右側）の端部近傍の位置は搬送対象である検体ラックを保持して搬送を開始する搬送開始位置１０３ａであり、この搬送開始位置１０３ａに前段側のベルトコンベア７ａの終端がくるように配置されている。テーブル１０２のＸ方向における他方側（図において左側）の端部近傍の位置は検体ラックの搬送完了位置１０３ｂとなっており、この搬送完了位置１０３ｂに後段側のベルトコンベア７ｂの始端がくるように配置されている。 The transport mechanism 100 includes a table 102 having a horizontal plane. The table 102 is supported by a base 118. The horizontal surface of the table 102 is set to be almost the same height as the conveying surfaces of the belt conveyors 7a and 7b arranged at both ends. A position in the vicinity of one end (right side in the figure) of the table 102 in the X direction is a transport start position 103a that starts the transport while holding the sample rack that is the transport target. It arrange | positions so that the terminal end of the belt conveyor 7a may come. The position near the end of the other side (left side in the figure) of the table 102 in the X direction is the sample rack transfer completion position 103b, so that the start end of the rear-stage belt conveyor 7b comes to this transfer completion position 103b. Has been placed.
　テーブル１０２上の両側縁部にＸ方向に延びた腕部材１０４と腕部材１０６が対向して配置されている。腕部材１０４と腕部材１０６はテーブル１０２の側縁部においてＸ方向とＹ方向へ駆動される。腕部材１０４と腕部材１０６は、Ｘ方向に対しては同時に同方向へ連動して移動し、Ｙ方向に対してテーブル１０２を中心として対称な方向へ連動して移動する。図には示されていないが、腕部材１０４と腕部材１０６を駆動するモータ等の機構は基台１１８の内部に収容されている。 The arm member 104 and the arm member 106 extending in the X direction are disposed opposite to both side edges on the table 102. The arm member 104 and the arm member 106 are driven in the X and Y directions at the side edge of the table 102. The arm member 104 and the arm member 106 move simultaneously in the same direction in the X direction and move in a symmetrical direction around the table 102 with respect to the Y direction. Although not shown in the drawing, the arm member 104 and a mechanism such as a motor for driving the arm member 106 are accommodated in the base 118.
　腕部材１０４は、搬送開始位置１０３ａ側の端部に突起１０４ａを備え、輸送完了位置１０３ｂ側の端部に突起１０４ｂを備えている。突起１０４ａと突起１０４ｂはＹ方向でテーブル１０２側へ突出している。検体ラック２０の側面には凹部（図示は省略）が設けられている。検体ラック２０は、その凹部がＹ方向で外側を向くようにテーブル２０上に載置される。突起１０４ａと１０４ｂは検体ラック２０のその凹部に嵌め込まれて検体ラックと係合するものである。腕部材１０４のＹ方向への移動は、突起１０４ａ，１０４ｂが検体ラックの凹部に嵌め込まれる位置と検体ラック自体に接触しない位置との間で行なわれる。 The arm member 104 includes a protrusion 104a at the end on the conveyance start position 103a side, and a protrusion 104b at the end on the transport completion position 103b side. The protrusions 104a and 104b protrude toward the table 102 in the Y direction. A recess (not shown) is provided on the side surface of the sample rack 20. The sample rack 20 is placed on the table 20 such that the concave portion faces outward in the Y direction. The protrusions 104a and 104b are fitted into the recesses of the sample rack 20 and engage with the sample rack. The movement of the arm member 104 in the Y direction is performed between a position where the protrusions 104a and 104b are fitted in the concave portion of the sample rack and a position where the arm member 104 does not contact the sample rack itself.
　腕部材１０６は、搬送開始位置１０３ａ側の端部に内側（Ｙ方向でテーブル１０２側）を向く突起１０６ａを備え、輸送完了位置１０３ｂ側にも内側を向く突起１０６ｂを備えている。突起１０６ａと突起１０６ｂは検体ラックの後背面（進行方向に対して）と係合するものである。腕部材１０６のＹ方向への移動は、突起１０６ａ，１０６ｂが検体ラックの背面に係合する位置と突起１０６ａ，１０６ｂが検体ラックに接触しない位置との間で行なわれる。 The arm member 106 includes a protrusion 106a facing the inner side (the table 102 side in the Y direction) at the end on the conveyance start position 103a side, and a protrusion 106b facing the inner side also on the transport completion position 103b side. The protrusion 106a and the protrusion 106b are engaged with the rear rear surface (in the traveling direction) of the sample rack. The movement of the arm member 106 in the Y direction is performed between a position where the protrusions 106a and 106b engage with the back surface of the sample rack and a position where the protrusions 106a and 106b do not contact the sample rack.
　腕部材１０４と１０６は、検体ラックを保持して搬送開始位置１０３ａから輸送完了位置１０３ｂまでテーブル１０２上をスライドさせて輸送するハンドラを構成している。このハンドラは、搬送開始位置１０３ａ側と輸送完了位置１０３ｂ側の２箇所で保持部を構成する。搬送開始位置１０３ａ側の保持部は腕部材１０４の突起１０４ａと腕部材１０６の突起１０６ａで構成され、輸送完了位置１０３ｂ側の保持部は腕部材１０４の突起１０４ｂと腕部材１０６の突起１０６ｂで構成される。 The arm members 104 and 106 constitute a handler that holds the sample rack and slides the table 102 from the transport start position 103a to the transport completion position 103b for transport. This handler constitutes a holding portion at two locations on the conveyance start position 103a side and the transport completion position 103b side. The holding portion on the transport start position 103a side is constituted by the projection 104a of the arm member 104 and the projection 106a of the arm member 106, and the holding portion on the transport completion position 103b side is constituted by the projection 104b of the arm member 104 and the projection 106b of the arm member 106. Is done.
　以下において、腕部材１０４と腕部材１０６をまとめて「ハンドラ１０４，１０６」、ハンドラ１０４，１０６の搬送開始位置１０３ａ側の保持部を「第１保持部１０４ａ，１０６ａ」、輸送完了位置１０３ｂ側の保持部を「第２保持部１０４ｂ，１０６ｂ」と称する。 Hereinafter, the arm member 104 and the arm member 106 are collectively referred to as “ handlers 104, 106”, the holding portions on the transfer start position 103a side of the handlers 104, 106 are referred to as “ first holding portions 104a, 106a”, and the transfer completion position 103b side. The holding unit is referred to as “ second holding unit 104b, 106b”.
　第１保持部１０４ａ，１０６ａは、ハンドラ１０４と１０６の搬送開始位置１０３ａ側の端部で検体ラックを両側から挟むことによって、検体ラックの一方側の側面の凹部に突起１０４ａを嵌め込むとともに検体ラックの反対側後背面を突起１０６ａで支持する。第２保持部１０４ｂ，１０６ｂは、腕部材１０４と１０６の搬送開始位置１０３ｂ側の端部で検体ラックを両側から挟むことによって、検体ラックの一側面の凹部に突起１０４ｂを嵌め込むとともに検体ラックの反対側後背面を突起１０６ｂで支持する。ハンドラ１０４，１０６は、検体ラックを保持した状態でＸ方向へ移動し、検体ラックをテーブル１０２上でスライドさせて輸送する。このハンドラ１０４，１０６は、遮蔽カバー１４が開かれたり停電などによって検体輸送装置１２の電源が切れたときには、オペレータが手動でＹ方向へ移動させることができる。検体ラックを保持しているハンドラ１０４，１０６をＹ方向へ移動させることで、検体ラックをハンドラ１０４，１０６から外すことができ、オペレータが検体輸送装置１２から検体ラックを取り出すことができる。 The first holding units 104a and 106a sandwich the sample rack from both sides at the end of the handlers 104 and 106 on the transport start position 103a side, thereby fitting the protrusion 104a into the concave portion on one side surface of the sample rack and the sample rack. The rear rear surface on the opposite side is supported by the protrusion 106a. The second holding units 104b and 106b sandwich the sample rack from both sides at the end of the arm members 104 and 106 on the transport start position 103b side, thereby fitting the protrusion 104b into the concave portion on one side of the sample rack and the sample rack. The opposite rear rear surface is supported by the protrusion 106b. The handlers 104 and 106 move in the X direction while holding the sample rack, and transport the sample rack by sliding it on the table 102. The handlers 104 and 106 can be manually moved in the Y direction by the operator when the shielding cover 14 is opened or the power of the sample transport device 12 is turned off due to a power failure or the like. By moving the handlers 104 and 106 holding the sample rack in the Y direction, the sample rack can be removed from the handlers 104 and 106, and the operator can take out the sample rack from the sample transport device 12.
　テーブル１０２の腕部材１０６側の側縁部には、テーブル１０２上をスライドする検体ラックの側面に設けられた溝に嵌め込まれて検体ラックの転倒を防止するガイドレール１０８が設けられている。 At the side edge of the table 102 on the arm member 106 side, a guide rail 108 that is fitted in a groove provided on the side surface of the sample rack that slides on the table 102 and prevents the sample rack from falling is provided.
　搬送開始位置１０３ａの側方には、搬送開始位置１０３ａへの検体ラックの到達を検知する第１センサ１１０が設けられている。輸送完了位置１０３ｂの側方には、輸送完了位置１０３ｂへの検体ラックの到達を検知する第２センサ１１２が設けられている。 A first sensor 110 that detects the arrival of the sample rack at the transfer start position 103a is provided on the side of the transfer start position 103a. A second sensor 112 for detecting the arrival of the sample rack at the transport completion position 103b is provided on the side of the transport completion position 103b.
　搬送開始位置１０３ａの近傍にストッパ１１４が設けられている。ストッパ１１４の構造及び動作については後述する。 A stopper 114 is provided in the vicinity of the conveyance start position 103a. The structure and operation of the stopper 114 will be described later.
　基台１１８の側部に回路基板に実装された輸送制御部１１６が設けられている。輸送制御部１１６はハンドラ１０４，１０６の動作を制御するものである。第１センサ１１０及び第２センサ１１２は配線によって輸送制御部１１６に接続され、それらの検知信号が輸送制御部１１６に取り込まれるようになっている。輸送制御部１１６は、第１センサ１１０が検体ラックの到達を検知したときの検知信号に基づいて検体ラックの輸送動作を開始するように構成されている。 A transportation control unit 116 mounted on a circuit board is provided on the side of the base 118. The transport control unit 116 controls the operation of the handlers 104 and 106. The first sensor 110 and the second sensor 112 are connected to the transport control unit 116 by wiring, and their detection signals are taken into the transport control unit 116. The transport control unit 116 is configured to start the transport operation of the sample rack based on the detection signal when the first sensor 110 detects the arrival of the sample rack.
　また、輸送制御部１１６は、図１１を用いて後述する演算制御装置３４と接続されており、第１センサ１１０と第２センサ１１２の検知信号が演算制御装置３４にも取り込まれるようになっている。検体輸送装置１２における検体ラックの輸送状態は演算制御装置３４によって管理されている。 Further, the transport control unit 116 is connected to an arithmetic control device 34 which will be described later with reference to FIG. 11, and detection signals of the first sensor 110 and the second sensor 112 are also taken into the arithmetic control device 34. Yes. The transport state of the sample rack in the sample transport device 12 is managed by the calculation control device 34.
　なお、図２及び図４では、配線や輸送制御部１１６に搭載されているモジュールの図示を省略している。図３では輸送制御部１１６に搭載されているモジュールの一部は図示しているが、配線の図示を省略している。 In FIGS. 2 and 4, illustration of the modules mounted on the wiring and transport control unit 116 is omitted. In FIG. 3, some of the modules mounted on the transport control unit 116 are illustrated, but illustration of wiring is omitted.
　ストッパ１１４の構造及び動作について図８Ａ及び図８Ｂを用いて説明する。
　ストッパ１１４は途中で略直角に屈折した部材である。ストッパ１１４の基端部はテーブル１０２の下方で搬送開始位置１０３ａ側の端部の下方に設けられた保持部材１２６に保持され、先端部が搬送開始位置１０３ａ側を向いている。ストッパ１１４の先端部はベルトコンベア７ａのローラ１４０の搬送機構の端部を越えてベルトコンベア７ａ上へ延び、検体ラック２０をベルトコンベア７ａ上で停止させる。 The structure and operation of the stopper 114 will be described with reference to FIGS. 8A and 8B.
The stopper 114 is a member refracted at a substantially right angle on the way. The base end portion of the stopper 114 is held by a holding member 126 provided below the table 102 and below the end portion on the conveyance start position 103a side, and the distal end portion faces the conveyance start position 103a side. The tip of the stopper 114 extends over the end of the conveying mechanism of the roller 140 of the belt conveyor 7a onto the belt conveyor 7a, and stops the sample rack 20 on the belt conveyor 7a.
　ストッパ１１４の基端を保持している保持部材１２６は鉛直方向への移動が可能であり、それによってストッパ１１４も上下動を行ない、ストッパ１１４の高さによって検体ラック２０の停止と解除を行なう。ストッパ１１４は、先端部がテーブル１０２よりも上方へ持ち上がった状態（図８Ａの状態）で検体ラック２０の停止を行ない、先端部がテーブル１０２と同じ高さ又はテーブル１０２の下方へ下降した状態（図８Ｂの状態）で検体ラック２０の停止を解除する。 The holding member 126 holding the base end of the stopper 114 can be moved in the vertical direction, so that the stopper 114 also moves up and down, and the sample rack 20 is stopped and released depending on the height of the stopper 114. The stopper 114 stops the sample rack 20 in a state where the tip end is lifted above the table 102 (state shown in FIG. 8A), and the tip end is lowered to the same height as the table 102 or below the table 102 ( The state of the sample rack 20 is released in the state of FIG. 8B.
　基台１１８側にＹ方向へ延びた固定軸１３０が取り付けられており（図６参照）、保持部材１２６と固定軸１３０がバネ１２８によって連結されている。バネ１２８は保持部材１２６を上昇させる方向に弾性力を作用させるように、自然長よりも延びた状態で保持部材１２６と固定軸１３０を連結している。 A fixed shaft 130 extending in the Y direction is attached to the base 118 side (see FIG. 6), and the holding member 126 and the fixed shaft 130 are connected by a spring 128. The spring 128 connects the holding member 126 and the fixed shaft 130 in a state of extending beyond the natural length so as to apply an elastic force in the direction in which the holding member 126 is raised.
　ハンドラ１０４，１０６と連動してＸ方向へ水平移動する摺動部１４２が設けられている。摺動部１４２は円形の断面を有する軸又は突起である。保持部材１２６の側部に連動部材１２７の一端が連結されている。連動部材１２７はハンドラ１０４，１０６による検体ラック２０の搬送方向（Ｘ方向）へ延びており、その上面１２７ａが摺動部１４２に常に接している。連動部材１２７の上面１２７ａは、直線部分と、保持部材１２６側へ行くにしたがって上昇する滑らかな斜面部分とを有し、摺動部１４２の水平移動に連動部材１２７の上面１２７ａが追従することで、保持部材１２６が上下動する。 A sliding portion 142 that moves horizontally in the X direction in conjunction with the handlers 104 and 106 is provided. The sliding portion 142 is a shaft or protrusion having a circular cross section. One end of the interlocking member 127 is connected to the side portion of the holding member 126. The interlocking member 127 extends in the transport direction (X direction) of the sample rack 20 by the handlers 104 and 106, and the upper surface 127 a is always in contact with the sliding portion 142. The upper surface 127a of the interlocking member 127 has a straight portion and a smooth slope portion that rises toward the holding member 126 side, and the upper surface 127a of the interlocking member 127 follows the horizontal movement of the sliding portion 142. The holding member 126 moves up and down.
　ハンドラの搬送開始位置１０３ａ側の保持部（突起部１０４ａ，１０６ａ）が搬送開始位置１０３ａよりも輸送完了位置１０３ｂ側にあるときには、ストッパ１１４がテーブル１０２よりも上方へ持ち上がった状態（図８Ａの状態）となり、ハンドラの搬送開始位置１０３ａ側の保持部（突起部１０４ａ，１０６ａ）が輸送開始位置にきたときにストッパ１１４がテーブル１０２と同じ高さ又はテーブル１０２の下方へ下降した状態（図８Ｂの状態）となるように、連動部材１２７の上面１２７ａの形状が調整されている。 When the holding portion ( protrusions 104a and 106a) on the handler transfer start position 103a is closer to the transport completion position 103b than the transfer start position 103a, the stopper 114 is lifted above the table 102 (the state shown in FIG. 8A). ), And the stopper 114 is lowered to the same height as the table 102 or below the table 102 when the holding portions ( projections 104a and 106a) on the transport start position 103a side of the handler come to the transport start position (see FIG. 8B). The shape of the upper surface 127a of the interlocking member 127 is adjusted so as to be in the state).
　次に、搬送機構１００による検体ラックの輸送動作の一例について図９及び図１０を用いて説明する。 Next, an example of the transport operation of the sample rack by the transport mechanism 100 will be described with reference to FIGS.
　検体容器１３８を保持した検体ラック２０が輸送開始位置であるベルトコンベア７ａの終端部に到達し第１センサ１１０が検体ラック２０を検知すると（図９（Ａ））、ハンドラ１０４，１０６が開いた状態で前段側コンベア７ａ側（図において右側）へ移動し（図９（Ｂ））、第１保持部１０４ａ，１０６ａで検体ラック２０を保持する（図９（Ｃ））。 When the sample rack 20 holding the sample container 138 reaches the end of the belt conveyor 7a, which is the transport start position, and the first sensor 110 detects the sample rack 20 (FIG. 9A), the handlers 104 and 106 are opened. In this state, it moves to the front conveyor 7a side (right side in the figure) (FIG. 9B), and the sample rack 20 is held by the first holding parts 104a and 106a (FIG. 9C).
　ハンドラ１０４，１０６は検体ラック２０を保持した状態でベルトコンベア７ｂ側（図において左側）へ移動し（図９（Ｄ））、テーブル１０２上の位置（一時配置部）で検体ラック２０を放す（図１０（Ｅ））。検体ラック２０をテーブル１０２上に載置した状態でハンドラ１０４，１０６のみが前段側コンベア７ａ側（図において右側）へ移動し（図１０（Ｆ））、第２保持部１０４ｂ，１０６ｂで検体ラック２０を保持する（図１０（Ｇ））。第２保持部１０４ｂ，１０６ｂで検体ラック２０を保持した状態で後段側コンベア７ｂ側（図において左側）へ移動し、後段側コンベア７ｂ上に検体ラック２０を載置する（図１０（Ｈ））。 The handlers 104 and 106 move to the belt conveyor 7b side (left side in the figure) while holding the sample rack 20 (FIG. 9D), and release the sample rack 20 at a position on the table 102 (temporary placement unit) ( FIG. 10 (E)). While the sample rack 20 is placed on the table 102, only the handlers 104 and 106 move to the front conveyor 7a side (right side in the figure) (FIG. 10F), and the sample racks are moved by the second holders 104b and 106b. 20 is held (FIG. 10G). While holding the sample rack 20 by the second holding units 104b and 106b, the sample rack 20 is moved to the rear conveyor 7b side (left side in the figure), and the sample rack 20 is placed on the rear conveyor 7b (FIG. 10H). .
　次に、この自動分析システム１全体の制御系統について図１１を用いて説明する。 Next, the control system of the entire automatic analysis system 1 will be described with reference to FIG.
　前段側自動分析装置２ａには採取分析部４ａ、搬送部６ａ及び検体導入機構１８ａの動作を制御する制御部３２ａが設けられ、後段側自動分析装置２ｂには採取分析部４ｂ、搬送部６ｂ及び検体導入機構１８ｂの動作を制御する制御部３２ｂが設けられている。検体輸送装置１２には搬送機構１００の動作を制御する輸送制御部１１６が設けられている。 The front-side automatic analyzer 2a is provided with a control unit 32a that controls the operation of the collection and analysis unit 4a, the transport unit 6a, and the sample introduction mechanism 18a. The rear-side automatic analyzer 2b includes the collection and analysis unit 4b, the transport unit 6b, and A control unit 32b that controls the operation of the sample introduction mechanism 18b is provided. The sample transport device 12 is provided with a transport control unit 116 that controls the operation of the transport mechanism 100.
　制御部３２ａ，３２ｂ及び１１６はそれぞれ演算制御装置３４と接続されている。演算制御装置３４には、検体に対して実行する分析項目に関する情報（分析項目情報）を保持する項目情報保持部３９と、オペレータによって指定された分析項目が前段側自動分析装置２ａ又は後段側自動分析装置２ｂにおいて実行されるように、項目情報保持部に保持されている分析項目情報に基づいた制御信号を制御部３２ａ又は３２ｂに送信する分析動作実行手段３５が設けられている。分析項目情報には、検体に添加する試薬の種類、試薬の量、攪拌の実行の有無などの情報が含まれる。オペレータによって実行すべき分析項目が指定されると、分析項目情報と後述する試薬情報記憶部４１の試薬情報から、その分析項目に使用される試薬が所定量だけ採取され、検体に添加されるようになっている。 The control units 32a, 32b, and 116 are connected to the arithmetic control device 34, respectively. In the arithmetic and control unit 34, an item information holding unit 39 that holds information (analysis item information) related to analysis items to be executed on the specimen, and an analysis item designated by the operator is sent to the front-side automatic analyzer 2a or the rear-side automatic An analysis operation execution means 35 is provided for transmitting a control signal based on the analysis item information held in the item information holding unit to the control unit 32a or 32b so as to be executed in the analysis device 2b. The analysis item information includes information such as the type of reagent added to the specimen, the amount of reagent, and whether or not stirring is performed. When an analysis item to be executed is designated by the operator, a predetermined amount of reagent used for the analysis item is collected from the analysis item information and reagent information in the reagent information storage unit 41 described later, and added to the sample. It has become.
　前段側自動分析装置２ａの採取分析部４ａで得られた測定データは制御部３２ａを介して演算制御装置３４に取り込まれ、後段側自動分析装置２ｂの採取分析部４ｂで得られた測定データは制御部３２ｂを介して演算制御装置３４に取り込まれる。演算制御装置３４は取り込んだ測定データを用いて検体中の成分の同定や定量を行なう機能をもっている。制御部３２ａ，３２ｂ及び輸送制御部１１６はそれぞれの装置の専用コンピュータにより実現される。演算制御装置３４は例えば汎用のパーソナルコンピュータ（ＰＣ）や専用のコンピュータにより実現される。演算制御装置３４には情報表示部４２が接続されており、演算制御装置３４でなされた演算結果などの情報が情報表示部４２に表示されるようになっている。情報表示部４２は例えば汎用のＰＣ用モニタや専用のモニタによって実現される。第１センサ１１０と第２センサ１１２の検知信号は輸送制御部１１６を介して演算制御装置３４に取り込まれるようになっている。 The measurement data obtained by the sampling analysis unit 4a of the upstream automatic analyzer 2a is taken into the arithmetic control device 34 via the control unit 32a, and the measurement data obtained by the sampling analysis unit 4b of the downstream automatic analyzer 2b is The data is taken into the arithmetic and control unit 34 through the control unit 32b. The arithmetic and control unit 34 has a function of identifying and quantifying the components in the specimen using the taken measurement data. The control units 32a and 32b and the transport control unit 116 are realized by dedicated computers of the respective devices. The arithmetic and control unit 34 is realized by, for example, a general-purpose personal computer (PC) or a dedicated computer. An information display unit 42 is connected to the calculation control device 34, and information such as calculation results made by the calculation control device 34 is displayed on the information display unit 42. The information display unit 42 is realized by, for example, a general-purpose PC monitor or a dedicated monitor. Detection signals of the first sensor 110 and the second sensor 112 are taken into the arithmetic control device 34 via the transport control unit 116.
　演算制御装置３４には、さらに、規則違反判定手段３６、情報表示手段３７、規則違反表示手段３８、規則保持部４０及び試薬情報記憶部４１が設けられている。ここでは、前段側自動分析装置２ａに情報読取器３３ａが設けられ、後段側自動分析装置２ｂに情報読取器３３ｂが設けられている場合について説明する。情報読取器３３ａ，３３ｂは例えばバーコードリーダーであり、採取分析部４ａ，４ｂの試薬設置部２２ａ，２２ｂに設置される試薬容器に貼付されたバーコードなどの情報媒体から情報を読み取るものである。 The arithmetic and control unit 34 is further provided with a rule violation determination unit 36, an information display unit 37, a rule violation display unit 38, a rule holding unit 40, and a reagent information storage unit 41. Here, a case will be described in which the information reader 33a is provided in the upstream automatic analyzer 2a and the information reader 33b is provided in the downstream automatic analyzer 2b. The information readers 33a and 33b are, for example, barcode readers, which read information from information media such as barcodes attached to reagent containers installed in the reagent installation units 22a and 22b of the collection analysis units 4a and 4b. .
　情報読取器３３ａ，３３ｂで読み取られた試薬情報は制御部３２ａ，３２ｂを介して演算制御装置３４に取り込まれ、試薬情報記憶部４１に記憶される。情報表示手段３７は、この演算制御装置３４における演算結果のほか、情報読取器３３ａ，３３ｂで読み取られた試薬情報の一覧を試薬情報リストとして情報表示部４２に表示するように構成されている。 The reagent information read by the information readers 33a and 33b is taken into the arithmetic and control unit 34 via the control units 32a and 32b and stored in the reagent information storage unit 41. The information display means 37 is configured to display a list of reagent information read by the information readers 33a and 33b on the information display unit 42 as a reagent information list in addition to the calculation result in the calculation control device 34.
　規則違反判定手段３６は、情報読取器３３ａ，３３ｂの読み取った試薬情報に基づき、その試薬の設置が所定の規則に違反するか否かを判定するように構成されている。この自動分析システムでは、各自動分析装置２ａ，２ｂの試薬設置部２２ａ，２２ｂへの試薬容器の設置について、以下の（１）及び（２）の規則が定められている。これらの規則（１）及び（２）は規則保持部４０に保持されている。
（１）１つの分析項目に使用される試薬がすべて１つの自動分析装置に設置されること。
（２）同じ種類の試薬が２つの自動分析装置に設置されないこと。 The rule violation determining means 36 is configured to determine whether or not the installation of the reagent violates a predetermined rule based on the reagent information read by the information readers 33a and 33b. In this automatic analysis system, the following rules (1) and (2) are established for the installation of reagent containers in the reagent installation sections 22a and 22b of the respective automatic analyzers 2a and 2b. These rules (1) and (2) are held in the rule holding unit 40.
(1) All reagents used for one analysis item are installed in one automatic analyzer.
(2) The same type of reagent should not be installed in the two automatic analyzers.
　規則違反表示手段３８は、規則違反判定手段３６による判定の結果、試薬の設置が上記の規則（１）、（２）のいずれかに違反する場合に、情報表示部４２に表示される試薬情報リストのうち、規則に違反している試薬情報の表示を他の試薬情報とは異なる表示にすることで、その試薬の配置が規則に違反していることをオペレータに認識させるように構成されている。 The rule violation display unit 38 displays reagent information displayed on the information display unit 42 when the reagent violation violates any of the rules (1) and (2) as a result of the determination by the rule violation determination unit 36. By configuring the display of reagent information that violates the rules in the list to be different from other reagent information, it is configured to allow the operator to recognize that the arrangement of the reagents violates the rules. Yes.
　上記の規則（１）に違反してある分析項目に使用される複数の試薬が別々の自動分析装置にわたって配置されている場合は、規則に違反している試薬を使用する分析項目を１つの自動分析装置で完結させることができないため、演算制御装置３４は、オペレータによるその分析項目の指定を禁止するようになっている。また、上記の規則（２）に違反して同じ種類の試薬が２つの自動分析装置に配置されている場合は、優先順位の高い方の自動分析装置（例えば、先にその試薬が設置された方の自動分析装置など）でのみその分析項目を実行し、他方の自動分析装置の試薬が違反していることを表示するようになっている。 When a plurality of reagents used for an analysis item that violates the above rule (1) are arranged across different automatic analyzers, an analysis item that uses a reagent that violates the rule is automatically selected. Since it cannot be completed by the analyzer, the arithmetic and control unit 34 prohibits the operator from specifying the analysis item. In addition, when the same type of reagent is placed in two automatic analyzers in violation of the above rule (2), the automatic analyzer with the higher priority (for example, the reagent was installed first) The analysis item is executed only by the other automatic analyzer, etc., and the fact that the reagent of the other automatic analyzer is violated is displayed.
　情報表示部４２に表示される表示画面の一例を図１３に示す。図１３は試薬情報リストの表示画面の一例であるが、この表示画面の右下のリストにおいて上から３番目の列に表記されている試薬が規則に違反しているため、この試薬の設置位置番号（Position.）「１」が赤色表記（他の試薬は黒色表記）される。 An example of a display screen displayed on the information display unit 42 is shown in FIG. FIG. 13 shows an example of the display screen of the reagent information list. Since the reagent indicated in the third column from the top in the list on the lower right of the display screen violates the rule, the installation position of this reagent is shown. The number (Position.) “1” is displayed in red (other reagents are displayed in black).
　なお、自動分析装置２ａ，２ｂに情報読取器３３ａ，３３ｂが設けられておらず、オペレータが試薬を手動で入力するようになっている場合には、オペレータの入力した試薬情報が試薬情報記憶部４１に記憶され、その入力された試薬情報が上記の規則に違反しているか否かが規則違反判定手段３６によって判定されるようになっている。 If the automatic analyzers 2a and 2b are not provided with the information readers 33a and 33b and the operator manually inputs the reagent, the reagent information input by the operator is stored in the reagent information storage unit. 41. The rule violation determining means 36 determines whether or not the inputted reagent information violates the above rule.
　また、オペレータは演算制御装置３４を介して各装置２ａ，２ｂ及び１１６の動作を個別に管理することができる。オペレータが演算制御装置３４を介して前段側自動分析装置２ａ、後段側自動分析装置２ｂ及び検体輸送装置１２の動作を個別に管理することで、前段側自動分析装置２ａと後段側自動分析装置２ｂの両方を用いて検体の分析を行なうほか、前段側自動分析装置２ａと後段側自動分析装置２ｂのいずれか一方の装置のみを動作させ、他方の装置を検体輸送装置１２とともに停止させることで、一方の装置のみで検体の分析を行なうこともできる。これにより、一方の自動分析装置や検体輸送装置１２に不具合が発生した場合であっても、不具合のない自動分析装置を単独で使用して検体の分析を行なうことができる。 Also, the operator can individually manage the operations of the devices 2a, 2b and 116 via the arithmetic and control unit 34. The operator individually manages the operations of the front-side automatic analyzer 2a, the rear-side automatic analyzer 2b, and the sample transport device 12 through the arithmetic and control unit 34, so that the front-side automatic analyzer 2a and the rear-side automatic analyzer 2b. In addition to performing analysis of the sample using both of the above, by operating only one of the front-side automatic analyzer 2a and the rear-side automatic analyzer 2b and stopping the other device together with the sample transport device 12, The sample can be analyzed with only one apparatus. As a result, even if a problem occurs in one of the automatic analyzers and the sample transport apparatus 12, the sample can be analyzed using an automatic analyzer that is free of defects.
　次に、この各自動分析装置２ａ，２ｂに試薬を設置する際の試薬情報の入力とその表示の一例について図１１とともに図１２のフローチャートを用いて説明する。ここでは、前段側自動分析装置２ａに情報読取器３３ａが設けられ、後段側自動分析装置２ｂに情報読取器３３ｂが設けられている場合について説明する。 Next, an example of the input of reagent information and the display thereof when the reagent is installed in each of the automatic analyzers 2a and 2b will be described using the flowchart of FIG. 12 together with FIG. Here, a case will be described in which the information reader 33a is provided in the upstream automatic analyzer 2a and the information reader 33b is provided in the downstream automatic analyzer 2b.
　オペレータが試薬設置部２２ａ又は２２ｂに試薬容器を設置し、その試薬容器に貼付されたバーコードが読み取られると、その試薬容器に収容された試薬の情報が演算制御装置３４に取り込まれ、その試薬容器が設置されている位置の情報（試薬ホルダー２３ａ又は２３ｂを特定する番号）とともに試薬情報記憶部４１に記憶される。その際、規則違反判定手段３６は、その試薬容器の設置が規則保持部４０に保持されている規則を確認し、その規則に違反しているか否かを判定する。試薬情報をオペレータが手動で入力するようになっている場合には、オペレータにより入力された試薬情報が試薬情報記憶部４１に記憶されるとともに、その試薬情報に基づいて規則違反判定手段３６がその試薬容器の設置が規則保持部４０の規則に違反しているか否かを判定する。 When an operator installs a reagent container in the reagent installing unit 22a or 22b and the barcode attached to the reagent container is read, information on the reagent contained in the reagent container is taken into the arithmetic and control unit 34, and the reagent The information is stored in the reagent information storage unit 41 together with information on the position where the container is installed (a number identifying the reagent holder 23a or 23b). At that time, the rule violation determination means 36 confirms the rule that the installation of the reagent container is held in the rule holding unit 40 and determines whether or not the rule is violated. When the operator manually inputs the reagent information, the reagent information input by the operator is stored in the reagent information storage unit 41, and the rule violation determining means 36 is based on the reagent information. It is determined whether or not the reagent container installation violates the rules of the rule holding unit 40.
　試薬容器の設置が規則に違反していない場合には、その試薬の関連項目情報を取得し、情報表示手段３７が情報表示部４２に表示する試薬情報リストにその試薬情報を通常表示するとともに、試薬情報リストを更新して試薬情報記憶部４１に記憶する。試薬容器の設置が規則に違反している場合には、情報表示部４２にその旨の警告を表示し、さらにその試薬情報の一部（例えば、試薬ホルダー番号）を他の試薬情報とは異なる色（例えば、赤色）にした状態で試薬情報リストに表示し、その試薬情報リストを更新して試薬情報記憶部４１に記憶する。以上の動作が試薬容器の設置の際に繰り返し行なわれる。 When the installation of the reagent container does not violate the rules, the related item information of the reagent is acquired, and the reagent information is normally displayed in the reagent information list displayed on the information display unit 42 by the information display unit 37, and The reagent information list is updated and stored in the reagent information storage unit 41. When the installation of the reagent container violates the rules, a warning to that effect is displayed on the information display unit 42, and a part of the reagent information (for example, reagent holder number) is different from other reagent information. The color information (for example, red) is displayed on the reagent information list, and the reagent information list is updated and stored in the reagent information storage unit 41. The above operation is repeated when the reagent container is installed.
　　　１　　　自動分析システム
　　　２ａ　　　前段側自動分析装置
　　　２ｂ　　　後段側自動分析装置
　　　４ａ，４ｂ　　　採取分析部
　　　６ａ，６ｂ　　　搬送部
　　　７ａ，７ｂ　　　ベルトコンベア
　　　８ａ，８ｂ　　　検体ラック配置部
　　　９ａ，９ｂ　　　検体ラック導入部
　　　１０ａ，１０ｂ　　　検体ラック回収部
　　　１２　　　検体輸送装置
　　　１４　　　遮蔽カバー
　　　１８ａ，１８ｂ　　　検体導入機構
　　　２０　　　検体ラック
　　　２２ａ，２２ｂ　　　試薬設置部
　　　２４ａ，２４ｂ　　　検体ラック収容部
　　　２６ａ，２６ｂ　　　測定部
　　　２８　　　ピン（マイクロスイッチ用）
　　　３０　　　マイクロスイッチ
　　　３２ａ，３２ｂ　　　制御部
　　　３４　　　演算制御装置
　　　３６　　　規則違反判定手段
　　　３７　　　情報表示手段
　　　３８　　　規則違反表示手段
　　　４０　　　規則保持部
　　　４１　　　試薬情報記憶部
　　　４２　　　情報表示部
　　　１００　　　搬送機構
　　　１０１ａ　　　Ｘ方向駆動モータ
　　　１０１ｂ　　　Ｙ方向駆動モータ
　　　１０２　　　テーブル
　　　１０３ａ　　　搬送開始位置
　　　１０３ｂ　　　搬送完了位置
　　　１０４，１０６　　　腕部材（ハンドラ）
　　　１０４ａ，１０４ｂ，１０６ａ，１０６ｂ　　　突起（保持部）
　　　１０８　　　ガイドレール
　　　１１０　　　第１センサ
　　　１１２　　　第２センサ
　　　１１４　　　ストッパ
　　　１１６　　　回路基板（制御部）
　　　１１６ａ　　　モータドライバ
　　　１１８　　　基台
　　　１２６　　　保持部材
　　　１２７　　　連動部材
　　　１２７　　　連動部材上面
　　　１２８　　　バネ
　　　１３０　　　固定軸
　　　１４０　　　ローラ
　　　１４２　　　摺動部 DESCRIPTION OF SYMBOLS 1 Automatic analysis system 2a The front | former stage side automatic analyzer 2b The back | latter stage side automatic analyzer 4a, 4b Sampling analysis part 6a, 6b Conveyance part 7a, 7b Belt conveyor 8a, 8b Sample rack arrangement | positioning part 9a, 9b Specimen rack introduction part 10a, 10b Specimen Rack collection unit 12 Sample transport device 14 Shielding cover 18a, 18b Sample introduction mechanism 20 Sample rack 22a, 22b Reagent installation unit 24a, 24b Sample rack storage unit 26a, 26b Measurement unit 28 pin (for micro switch)
30 Microswitch 32a, 32b Control unit 34 Arithmetic control device 36 Rule violation determination unit 37 Information display unit 38 Rule violation display unit 40 Rule holding unit 41 Reagent information storage unit 42 Information display unit 100 Transport mechanism 101a X direction drive motor 101b Y direction Drive motor 102 Table 103a Transfer start position 103b Transfer completion position 104, 106 Arm member (handler)
104a, 104b, 106a, 106b Protrusion (holding part)
108 Guide rail 110 First sensor 112 Second sensor 114 Stopper 116 Circuit board (control unit)
116a Motor driver 118 Base 126 Holding member 127 Interlocking member 127 Upper surface of interlocking member 128 Spring 130 Fixed shaft 140 Roller 142 Sliding part

Claims (7)

  1. 　複数の自動分析装置、それらの自動分析装置のうち隣接する自動分析装置の間に配置されて隣接する自動分析装置を連結する検体輸送装置、及び前記自動分析装置と前記検体輸送装置のすべてに接続されて該自動分析システム全体の動作管理を行なう演算制御装置を備え、
    　前記自動分析装置の各々は、検体容器を保持した検体ラックを搬送するベルトコンベア、複数の試薬を設置する試薬設置部、検体容器から検体を採取するとともに前記試薬設置部の試薬をその検体に添加して反応させて分析を行なう採取分析部及び前記ベルトコンベア上の検体ラックを保持して前記採取分析部へ導入する検体導入機構をそれぞれ独自に備えており、
    　前記検体輸送装置は、互いに隣接する前記自動分析装置のうち一方のベルトコンベアの終端で検体ラックを保持して他方のベルトコンベアの始端まで搬送する搬送機構を備えたものであり、
    　前記各自動分析装置の前記試薬設置部に設置されている試薬の情報を取得する試薬情報取得手段を備え、
    　前記演算制御装置は、いずれかの前記自動分析装置において実行されうる分析項目で使用される試薬の情報を保持する項目情報保持部、前記各自動分析装置の前記試薬設置部に設置される試薬についての規則の一つとして、１つの分析項目で使用されるすべての試薬が１つの前記自動分析装置に設置されていなければならないという規則を保持する規則保持部、前記各自動分析装置の前記試薬設置部に設置されている試薬が前記規則に反するか否かを判定する規則違反判定手段、及び前記試薬設置部に設置されている試薬が前記規則に反する場合に、その旨をオペレータの認識しうる方法で表示するように構成されている規則違反表示手段を備えている自動分析システム。     A plurality of automatic analyzers, a sample transport device that is arranged between adjacent automatic analyzers among the automatic analyzers and connects adjacent automatic analyzers, and connected to all of the automatic analyzers and the sample transport devices An arithmetic and control unit that performs operation management of the entire automatic analysis system,
    Each of the automatic analyzers includes a belt conveyor for transporting a sample rack holding a sample container, a reagent installing unit for installing a plurality of reagents, collecting a sample from the sample container, and adding the reagent of the reagent installing unit to the sample And a sample introduction mechanism for holding the sample rack on the belt conveyor and introducing it into the collection analysis unit, each of which has its own analysis.
    The sample transport device includes a transport mechanism that holds the sample rack at the end of one belt conveyor of the automatic analyzers adjacent to each other and transports the sample rack to the start end of the other belt conveyor,
    Reagent information acquisition means for acquiring information on the reagent installed in the reagent installation unit of each automatic analyzer,
    The arithmetic and control unit includes an item information holding unit for holding information on a reagent used in an analysis item that can be executed in any of the automatic analyzers, and a reagent installed in the reagent installing unit of each of the automatic analyzers As one of the rules, a rule holding unit that holds a rule that all reagents used in one analysis item must be installed in one automatic analyzer, and the reagent installation of each automatic analyzer The rule violation determination means for determining whether or not the reagent installed in the section violates the rule, and when the reagent installed in the reagent installation section violates the rule, the operator can recognize that fact An automated analysis system comprising rule violation display means configured to display in a method.
  2. 　前記演算制御装置は、検体に対して実行すべき分析項目として指定された分析項目のそれぞれについて、前記試薬情報取得手段によって前記各自動分析装置に設置されている試薬を確認し、指定の分析項目で使用する試薬のすべてが設置されている前記自動分析装置をその分析項目を実行する前記自動分析装置として選択するように構成された項目実行装置選択手段をさらに備えている請求項１に記載の自動分析システム。 The arithmetic and control unit confirms the reagent installed in each automatic analyzer by the reagent information acquisition means for each analysis item designated as an analysis item to be executed on the sample, and designates the designated analysis item. The apparatus according to claim 1, further comprising: an item execution device selection unit configured to select the automatic analysis device in which all of the reagents used in the step are installed as the automatic analysis device that executes the analysis item. Automatic analysis system.
  3. 　前記規則保持部は、同じ種類の試薬が複数の前記自動分析装置に設置されてはならないという規則も保持している請求項２に記載の自動分析システム。 The automatic analysis system according to claim 2, wherein the rule holding unit also holds a rule that the same type of reagent should not be installed in a plurality of the automatic analyzers.
  4. 　前記演算制御装置に接続され、情報を表示する情報表示部をさらに備え、
    　前記演算制御装置は、前記各自動分析装置の前記試薬設置部に設置されている試薬の情報の一覧を前記情報表示部に表示するように構成された情報表示手段をさらに備え、
    　前記規則違反表示手段は、前記情報表示手段により前記情報表示部に表示された試薬の情報の一覧のうち前記規則に違反している試薬の情報の一部分を他の試薬容器の情報の同じ部分とは異なる色で表示するように構成されている請求項１から３のいずれか一項に記載の自動分析システム。     An information display unit connected to the arithmetic and control unit and displaying information;
    The arithmetic and control unit further includes an information display unit configured to display a list of information on the reagents installed in the reagent installation unit of each automatic analyzer on the information display unit,
    The rule violation display means includes a part of the information on the reagent displayed on the information display unit by the information display means as a part of the information on the other reagent containers. The automatic analysis system according to claim 1, wherein the automatic analysis system is configured to display in different colors.
  5. 　前記試薬情報取得手段は、各試薬に添付されその試薬の情報を記録した情報媒体及び前記試薬設置部に設置される試薬の前記情報媒体から情報を読み取る情報読取器によって構成されるものである請求項１から４のいずれか一項に記載の自動分析システム。 The reagent information acquisition means is configured by an information medium attached to each reagent and recording information of the reagent, and an information reader that reads information from the information medium of the reagent installed in the reagent installation unit. Item 5. The automatic analysis system according to any one of Items 1 to 4.
  6. 　前記情報媒体はバーコードであり、前記情報読取器はバーコードリーダーである請求項５に記載の自動分析システム。 The automatic analysis system according to claim 5, wherein the information medium is a barcode, and the information reader is a barcode reader.
  7. 　前記試薬情報取得手段は、前記試薬設置部に設置された試薬の情報をオペレータに入力させ、入力された情報を記憶するように構成されたものである請求項１から４のいずれか一項に記載の自動分析システム。 The said reagent information acquisition means is comprised so that an operator may input the information of the reagent installed in the said reagent installation part, and memorize | stores the input information. Automatic analysis system described.
PCT/JP2013/083083 2013-12-10 2013-12-10 Automatic analysis system formed by linking plurality of analysis devices WO2015087393A1 (en)

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JPH08262031A (en) * 1995-03-17 1996-10-11 Hitachi Ltd Autoanalyzer
JPH08271517A (en) * 1995-03-31 1996-10-18 Toshiba Corp Reagent system for chemical analyzer
JPH0954096A (en) * 1995-08-16 1997-02-25 A & T:Kk Conveyor for use in specimen conveying system
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JPH0526882A (en) * 1991-07-16 1993-02-02 Hitachi Ltd Multiitem simultaneous-processing automatic analyzer and its analysis processing method
JPH08262031A (en) * 1995-03-17 1996-10-11 Hitachi Ltd Autoanalyzer
JPH08271517A (en) * 1995-03-31 1996-10-18 Toshiba Corp Reagent system for chemical analyzer
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