JPH05230097A - B型肝炎ウイルスのHBc抗原由来の合成ペプチド、このウイルスによる感染を検出すること及び抗B型肝炎ワクチンのための該ペプチドの使用 - Google Patents
B型肝炎ウイルスのHBc抗原由来の合成ペプチド、このウイルスによる感染を検出すること及び抗B型肝炎ワクチンのための該ペプチドの使用Info
- Publication number
- JPH05230097A JPH05230097A JP4002647A JP264792A JPH05230097A JP H05230097 A JPH05230097 A JP H05230097A JP 4002647 A JP4002647 A JP 4002647A JP 264792 A JP264792 A JP 264792A JP H05230097 A JPH05230097 A JP H05230097A
- Authority
- JP
- Japan
- Prior art keywords
- arg
- leu
- ser
- val
- peptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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- 230000004044 response Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 239000012047 saturated solution Substances 0.000 description 1
- 230000008313 sensitization Effects 0.000 description 1
- 230000000405 serological effect Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000000638 solvent extraction Methods 0.000 description 1
- 210000004989 spleen cell Anatomy 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 125000005931 tert-butyloxycarbonyl group Chemical group [H]C([H])([H])C(OC(*)=O)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 125000002088 tosyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])S(*)(=O)=O 0.000 description 1
- 238000012800 visualization Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
- C07K16/082—Hepadnaviridae, e.g. hepatitis B virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9100273 | 1991-01-11 | ||
FR9100273A FR2671554A1 (fr) | 1991-01-11 | 1991-01-11 | Peptides synthetiques derivant de l'antigene hbc du virus de l'hepatite b, leurs applications a la detection d'une infection par ce virus et a la vaccination contre l'hepatite b. |
Publications (1)
Publication Number | Publication Date |
---|---|
JPH05230097A true JPH05230097A (ja) | 1993-09-07 |
Family
ID=9408604
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP4002647A Pending JPH05230097A (ja) | 1991-01-11 | 1992-01-10 | B型肝炎ウイルスのHBc抗原由来の合成ペプチド、このウイルスによる感染を検出すること及び抗B型肝炎ワクチンのための該ペプチドの使用 |
Country Status (6)
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7323331B2 (en) | 2000-08-11 | 2008-01-29 | Advanced Life Science Institute, Inc. | Method for detecting or assaying HBV |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1338310A (zh) * | 2000-08-10 | 2002-03-06 | 清华大学 | 一种猪瘟病毒表位疫苗及其制备方法 |
CN1339320A (zh) * | 2000-08-18 | 2002-03-13 | 清华大学 | 一种艾滋病疫苗及其制备方法与应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE56026B1 (en) * | 1982-10-19 | 1991-03-27 | Cetus Corp | Cysteine-depleted muteins of biologically active proteins |
US4882145A (en) * | 1986-12-09 | 1989-11-21 | Scripps Clinic And Research Foundation | T cell epitopes of the hepatitis B virus nucleocapsid protein |
DE68929273T2 (de) * | 1988-08-24 | 2001-07-05 | American Cyanamid Co | Stabilisierung von Somatotropinen durch Modifikation von Cystein-Resten durch orts-spezifische Mutagenese oder chemische Derivatisierung |
-
1991
- 1991-01-11 FR FR9100273A patent/FR2671554A1/fr not_active Withdrawn
-
1992
- 1992-01-09 DE DE199292400053T patent/DE494825T1/de active Pending
- 1992-01-09 ES ES92400053T patent/ES2042481T1/es active Pending
- 1992-01-09 EP EP92400053A patent/EP0494825A1/fr not_active Withdrawn
- 1992-01-10 JP JP4002647A patent/JPH05230097A/ja active Pending
-
1993
- 1993-03-16 GR GR920300134T patent/GR920300134T1/el unknown
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7323331B2 (en) | 2000-08-11 | 2008-01-29 | Advanced Life Science Institute, Inc. | Method for detecting or assaying HBV |
Also Published As
Publication number | Publication date |
---|---|
FR2671554A1 (fr) | 1992-07-17 |
EP0494825A1 (fr) | 1992-07-15 |
GR920300134T1 (US07902200-20110308-C00004.png) | 1993-03-16 |
ES2042481T1 (es) | 1993-12-16 |
DE494825T1 (de) | 1993-01-14 |
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