JPH05194129A - Bactericidal agent for agriculturaland gardening purposes - Google Patents

Abstract

PURPOSE: To obtain an agricultural and horticultural fungicide having remarkable effects on prevention and treatment of late blight and downy mildew of vegetables, flower and ornamental plants, fruit trees, etc. CONSTITUTION: This agricultural and horticultural fungicide comprises cymoxanil and phosethyl as active ingredients. Tetrachloroisophthanyl or a basic inorganic copper compound can further be formulated with the fungicide. Basic copper sulfate or basic copper chloride is preferred as the basic inorganic copper compound.

Description

Detailed Description of the Invention

[0001]

FIELD OF THE INVENTION The present invention relates to a novel fungicide for agricultural and horticultural use. INDUSTRIAL APPLICABILITY The fungicide for agricultural and horticultural use of the present invention is effectively used for controlling diseases of agricultural crops, in particular, important diseases including epidemics such as vegetables, flowers and fruit trees, downy mildew and powdery mildew.

[0002]

2. Description of the Related Art Simoxanil, which is one of the active ingredients of the agricultural and horticultural fungicide of the present invention, is a disease caused by certain algae ( Phycomycetes ), such as lateblight of tomato and potato and grape. It is known to be particularly effective in controlling downy mildew (Japanese Patent Laid-Open No. 52-36626).

[0003] Simoxanil can be applied not only to parts of the plant that are at risk of infection with phytopathogenic fungi, but also to uninfected parts or soil where plants grow to prevent plant diseases.

[0004] Further, since Simoxanil is absorbed in the plant and migrates in the plant, it can inactivate pathogens that have already been infected and treat plant diseases.

As described above, cimoxanil has an excellent control effect against plant diseases, but has a problem that the residual effect when applied to plants is not always sufficient. Therefore, the present inventors, while maintaining the features of Simoxanil, and as a result of intensive studies to provide an agricultural and horticultural fungicide having an excellent residual effect, as a result, Simoxanil was identified as a specific agricultural and horticultural fungicide. The present invention has been completed, knowing that when used in combination, the bactericidal efficacy of cimoxanil is synergistically improved, and the problem of residual efficacy is eliminated.

[0006]

The present invention comprises an agricultural and horticultural fungicide containing cimoxanil and fosetyl as active ingredients. Further, the present invention comprises an agricultural and horticultural fungicide containing cimoxanil, fosetyl and tetrachloroisophthalonitrile as active ingredients.

The present invention further comprises an agricultural and horticultural fungicide containing cimoxanil, fosetyl and a basic inorganic copper agent as active ingredients.

The cimoxanil (2-cyano-N-[(ethylamino) carbonyl] -2- (methoxyimino) acetamide) used as an active ingredient in the present invention is a compound known as an agricultural / horticultural fungicide as described above. is there.

Fosetyl (aluminum = tris (ethyl = phosphonate)) is known as a fungicide having an excellent preventive effect against diseases such as downy mildew and plague of various vegetables. Improve defense function. Tetrachloroisophthalonitrile (TPN) is known as a fungicide with excellent effect of preventing various diseases such as downy mildew, powdery mildew, plague and gray mold of various vegetables, it is chemically stable and has a residual effect. Is excellent in

In the present invention, as the basic inorganic copper agent, those known as a bactericide such as basic copper sulfate or basic copper chloride are used. In these copper agents, water-insoluble copper compounds adhere to the target crop as fine particles, and gradually release copper ions (Cu ⁺⁺ ) due to carbon dioxide gas and organic acids, etc. Protect.

The agricultural and horticultural germicide of the present invention can be used by formulating the active ingredient together with a carrier and various auxiliary agents into a wettable powder, an emulsion, a powder, a granule, a flowable powder and the like by a conventional method. Examples of carriers used include solid carriers such as clay, talc, bentonite, kaolin, diatomaceous earth, silica and sucrose, or benzene, xylene, toluene, kerosene, alcohols (methanol, ethanol, isopropanol, n-butanol, etc.). ), Ketones (acetone, methyl ethyl ketone, cyclohexane, etc.) and the like. Appropriate surfactants and other auxiliaries such as stabilizers and spreading agents may be added to these in appropriate amounts to form a formulation for use.

The agricultural and horticultural fungicide of the present invention can be used by mixing each active ingredient with a suitable carrier as described above to prepare a formulation, which can be diluted to an appropriate concentration at the time of application. It is also possible to prepare a diluting solution by mixing a single agent in which each active ingredient is formulated so as to have a suitable concentration for use at the time of application.

The blending ratio of the active ingredient is not critical, but the weight ratio of fosetyl to 1.5 parts of cimoxanil is 1.5.
~ 3 parts, TPN 0.5-1.5 parts, basic inorganic copper agent 0.5
~ 2 parts are suitable. However, the compounding ratio can be appropriately changed and used according to the conditions at the time of application. Further, other fungicides, insecticides, herbicides, plant growth regulators and the like can also be appropriately mixed and used within a range that does not impair the particular effects of the present invention.

The fungicide for agricultural and horticultural use of the present invention can be used for the prevention and treatment of downy mildew, plague, powdery mildew, ring spot disease, summer plague, etc. of various vegetables, flowers and fruits. It has a special control effect against the epidemics of tomatoes, ring spots, epidemics of potatoes, summer epidemics, downy mildew of cucumber and powdery mildew.

When the agricultural and horticultural fungicide of the present invention is applied to a field, the amount of the active ingredient per 10 ares (as cimoxanil) is usually in the range of 10 g to 500 g, and the concentration of application of the active ingredient (as cimoxanil concentration) is 0. 0.002 to 1.
It can be applied in the range of 0%. However, the application amount and application concentration can be changed as appropriate according to application conditions and damage conditions.

[0016]

EXAMPLES Next, the present invention will be described more specifically by showing examples. In the examples, all parts are parts by weight.

Example 1 (wettable powder) 17 parts of cimoxanil, 40 parts of fosetyl, 2 parts of sodium alkylnaphthalene sulfonate, 2 parts of sodium lignin sulfonate, 3 parts of synthetic amorphous silica and 13 parts of kaolinite are mixed sufficiently. It was crushed to obtain a wettable powder.

Example 2 (wettable powder) 17 parts of cimoxanil, 40 parts of fosetyl, 14 parts of TPN,
Sodium alkylnaphthalene sulfonate 2 parts, sodium lignin sulfonate 2 parts, synthetic amorphous silica 3
And 13 parts of kaolinite were mixed and sufficiently pulverized to obtain a wettable powder.

Example 3 (wettable powder) A wettable powder was obtained by using 14 parts of basic copper sulfate instead of 14 parts of TPN in Example 2.

Next, the sterilizing effect of the agricultural / horticultural germicide of the present invention will be specifically described with reference to test examples.

Test Example 1 Tomato Late Blight Control Effect Test Tomato (6-7 leaf stage of red cherry variety) cultivated in a black poly pot having a diameter of 12 cm was infected with the tomato blight ( Phytophtho).
A zoospore suspension of ra infestans , Phytophytra infestans ) was sprayed with a small atomizer. Bacteria were inoculated in a Coittron (inoculation box) at 21 ° C. and humidity of 100% for 24 hours, and thereafter, they were carried out to a glass room and managed until they were examined. For the spraying of chemicals, the wettable powder of the reagent to be used is diluted to a prescribed concentration and the diluted mixture is 20 ml (15 sprayed in 10 ares).
0 liter) was sprayed on the tomato seedlings with a small sprayer.
In the test for the preventive effect, the bacteria were inoculated after spraying the drug, and in the test for the therapeutic effect, the drug was sprayed 24 hours after the inoculation of the bacteria, and the investigation was conducted 7 to 10 days after the inoculation.

In the pathogenicity investigation, except for the lowermost leaf, 5 leaves from the lower 2 leaves to the upper part were usually used as the leaves to be investigated. Disease occurrence was investigated by degree, and diseased leaf rate, disease severity and control value were calculated.

[0023]

[Equation 1] (Index) 0: No lesions are observed on leaves 0.5: Lesions are observed on less than 2% of leaves 1: Lesions are observed on less than 2 to 10% of leaves 2: 10 on leaves Lesions are observed in less than -50% 3: Lesions are observed in less than 50-70% of leaves 4: Lesions are observed in 70% or more of leaves

[0024]

[Equation 2]

The test was carried out in 3 repetitions of 5 strains (5 pots) in 1 ward. As a result of the test, the preventive effect was that all of the test reagents had a control value of 100. The therapeutic effect was as shown in Table 1. No phytotoxicity to tomato seedlings was observed in any of the reagents.

[0026]

[Table 1]

The control value of the mixture of the 1000-fold liquid of Carzet wettable powder and the 800-fold liquid of Arrietty wettable powder increased from 36.7 to 64.6 as compared with the single agent, and a synergistic effect was recognized. On the other hand, in the case of the mixture of 1000 times liquid of Carzet wettable powder and 600 times liquid of Eupalene wettable powder (control), the control value decreased from 36.7 as a single agent to 29.1.

Test Example 2 In the same manner as in Test Example 1, a residual effect test for controlling the tomato epidemic of the reagent was conducted. Four days after spraying the drug, zoospores were inoculated, and on the 16th day, the diseased leaf rate and disease severity were investigated, and the control value was calculated. The results are shown in Table 2.

[0029]

[Table 2]

From the above results, the residual effect period of the test reagent of Test Example 2 was sufficiently observed until the 4th day. Furthermore, a synergistic effect of the mixture of Carzet wettable powder, Arrietti wettable powder and Z Bordeaux wettable powder was also observed. It was found that the dilution of carzet wettable powder was effective even 2000 times.

Test Example 3 In the same manner as in Test Example 1, the preventive and therapeutic effects of the fungicide of the present invention against tomato epidemics were tested and the control value was calculated. The test was repeated 3 times with 5 strains (5 pots) in 1 ward. The results are shown in Table 3.

[0032]

[Table 3]

A mixed solution of 2000% Carzet wettable powder, 1000 times German Bordeaux A wettable powder and 1000 times Arietti wettable powder showed synergistically superior therapeutic effects as compared with the respective single agents. .. In addition, the therapeutic effect was superior to that of the 1000 times solution of the control agent, Lidomyl MZ wettable powder.

Test Example 4 Test Example 1 was prepared by further increasing the dilution factor of the carzet wettable powder.
Similarly to the above, the preventive and therapeutic effects of the fungicide of the present invention against tomato epidemic were tested and the control value was calculated. The results are shown in Table 4.

[0035]

[Table 4]

2000 times solution of Carzet wettable powder and 3
A solution prepared by mixing an Arietti wettable powder 1000 times solution and a TPN / FL agent 2000 times solution to a 000 times solution showed a control value of 100 at both concentrations, and no difference was observed between the concentrations. From this result, when the Arrietti wettable powder 1000 times solution and the TPN / FL 2000 times solution were mixed,
It was confirmed that the concentration of carzet in the fungicide of the present invention against tomato epidemic was 3000 times, and a sufficient control effect was obtained.

Test Example 5 The preventive and therapeutic effects of the fungicide of the present invention against tomato epidemic were tested in the same manner as in Test Example 1 by further increasing the dilution ratios of carzet wettable powder, Arrietty wettable powder and TPN.FL. The control value was calculated. The results are shown in Table 5.

[0038]

[Table 5]

As is clear from Table 5, a sufficient controlling effect was obtained even with a mixture of a 3000-fold solution of carzet wettable powder, a 2000-fold solution of Arrietti wettable powder and a 3000-fold solution of TPN / FL.

Test Example 6 Cucumber downy mildew control effect test (preventive effect test) Cucumber seedlings (cultivar Tokiwa Hikari No. 3 P type) cultivated in a black polypot with a diameter of 15 cm were placed in a glass greenhouse under natural disease-causing conditions. Tested. The test was conducted from the time when the cotyledons were completely developed to the 7-leaf stage. In the preventive effect test, the drug was sprayed from the cotyledon stage to prevent natural infection before the start of the test.

The chemicals were sprayed 20 times per pot (150 liters in equivalent spray amount per 10 ares), three times in total. The disease investigation targeted 5 leaves from 2 to 6 leaves.
The control value was calculated in the same manner as in Test Example 1. 1 ward 5 shares (5
Pot) 3 repetitions. Drug application date: 1st June 10th, 2nd June 16th, 3rd June 23rd. Onset date 6
30th of the month. The results are shown in Table 6.

[0042]

[Table 6]

The effect of the pre-onset spraying (preventive spraying) on the cucumber downy mildew of the mixture consisting of the 2000-fold solution of Carzet wettable powder, the 1000-fold solution of Arrietty wettable powder and the 2000-fold solution of German Bordeaux A wettable powder is It was superior to the effects of wettable powder, German Bordeaux A wettable powder, and TPN / FL alone.

No difference in preventive effect was observed between the single-use caserate wettable powder and the above-mentioned mixed agent. If the date of onset investigation is further delayed and the effect of residual efficacy is investigated, a clear difference may be observed between the two.

Test Example 7 Control Effect of Cucumber Powdery Mildew According to the method of Test Example 5, the preventive effect of the fungicide of the present invention against cucumber powdery mildew was tested. The results are shown in Table 7.

[0046]

[Table 7]

The mixture of carzet wettable powder, Arrietti wettable powder and German Bordeaux A wettable powder was superior in preventive effect to TPN / FL as the single agent and the control agent.

Test Example 8 Tomato epidemic control test (field test) Target disease occurrence status The first occurrence of the disease was confirmed on September 20, and after that, due to long rain, it frequently occurred at the time of survey. Cultivation outline (cultivar / fertilization / general management) Variety: Fengryu, sowing: July 13th, planting: August 19th, open field cultivation, cultivation distance: 50cm between plants x 100cm between ridges, cultivation management: side branching, using silver mulch , Fertilization and other general management were in accordance with the practice. Ward / Area 1 Ward: 5m ² (12 shares) 3 consecutive treatments Date of treatment, quantity, method, crop stage at the time of treatment, and effects of rainfall before and after treatment September 17 (high growth stage), 24 days, 3 times on October 2nd,
Spraying was carried out at a rate of 280 liters per 10a using a backpack type automatic sprayer. There was no effect of rainfall before and after spraying. Survey Date / Method On October 8th (6 days after the final application), 12 strains in each ward were investigated for the degree of disease, and the rate of disease-causing strain and the degree of disease were calculated.
(Survey criteria are as shown below). The phytotoxicity was observed by naked eyes at any time. Others In order to promote disease outbreak, diseased strains were set up in the buffer zone (during the first spraying). The results are shown in Table 8.

[0049]

[Table 8]

Note) Duncan's multipl is the same between lowercase letters.
It shows that there is no 5% significant difference by e range test. The control value was calculated from the disease severity.

[0051]

[Equation 3]

(Index) 0: No lesion is observed on the foliage 0.5: Lesion is observed on less than 2% of the foliage 1: Lesion is observed on 2 to less than 10% of the foliage 2: Lesions are observed in 10 to less than 50% of the foliage 3: Lesions are observed in 50 to less than 70% of the foliage 4: Lesions are observed in 70% or more of the foliage

It is clear from Table 8 that the fungicide of the present invention comprising a combination of cimoxanil, fosetyl and TPN has a remarkable effect even in the field test.

[0054]

INDUSTRIAL APPLICABILITY The agricultural / horticultural fungicide of the present invention has an excellent bactericidal effect, and has penetrative transferability to plants and residual effect, so that it can cause diseases of crops, especially vegetables, flowers, fruit trees and the like. It has an excellent preventive and curative effect against the plague, downy mildew and powdery mildew. Further, it is also effective against the plague and downy mildew having resistance to the conventionally used drugs.
Further, it is also effective against Alternaria bacterium, anthracnose bacterium (Choletotrichrome bacterium) and vine wilt bacterium (Mycosferrera bacterium).

The effect of the bactericide of the present invention is a remarkable synergistic effect which cannot be expected from the single use of each active ingredient, and the dose to be used can be significantly reduced. Therefore, not only economy,
It is an agricultural and horticultural fungicide with excellent safety that can reduce phytotoxicity to crops, toxicity to humans and animals, and residual toxicity.

─────────────────────────────────────────────────── ─── Continuation of the front page (51) Int.Cl. ⁵ Identification code Office reference number FI technical indication location A01N 37:34) (A01N 57/12 47:34 59:20) (72) Inventor Makoto Tsuchizawa Tokyo 2-10-1 Toranomon, Minato-ku, Nippon Mining Building DuPont Tower DuPont Japan Limited

Claims (5)

[Claims] 1. A fungicide for agricultural and horticultural use, which comprises cimoxanil and fosetyl as active ingredients. 2. A fungicide for agricultural and horticultural use, which comprises cimoxanil, fosetyl and tetrachloroisophthalanil as active ingredients. 3. A fungicide for agricultural and horticultural use, which comprises cimoxanil, fosetyl and a basic inorganic copper agent as active ingredients. 4. The agricultural and horticultural fungicide according to claim 3, wherein the basic inorganic copper agent is basic copper sulfate. 5. The fungicide for agricultural and horticultural use according to claim 3, wherein the basic inorganic copper agent is basic copper chloride.