JPH0415019B2 - - Google Patents
Info
- Publication number
- JPH0415019B2 JPH0415019B2 JP10059286A JP10059286A JPH0415019B2 JP H0415019 B2 JPH0415019 B2 JP H0415019B2 JP 10059286 A JP10059286 A JP 10059286A JP 10059286 A JP10059286 A JP 10059286A JP H0415019 B2 JPH0415019 B2 JP H0415019B2
- Authority
- JP
- Japan
- Prior art keywords
- reaction
- reagent
- reaction reagent
- solid
- solid phase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000003153 chemical reaction reagent Substances 0.000 claims description 59
- 238000006243 chemical reaction Methods 0.000 claims description 52
- 239000007788 liquid Substances 0.000 claims description 43
- 238000003746 solid phase reaction Methods 0.000 claims description 36
- 239000000376 reactant Substances 0.000 claims description 9
- 238000000034 method Methods 0.000 description 13
- 239000012071 phase Substances 0.000 description 12
- 238000003756 stirring Methods 0.000 description 9
- 230000000694 effects Effects 0.000 description 7
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 5
- 229910001873 dinitrogen Inorganic materials 0.000 description 5
- 239000007789 gas Substances 0.000 description 3
- 239000002773 nucleotide Substances 0.000 description 3
- 125000003729 nucleotide group Chemical group 0.000 description 3
- 239000007790 solid phase Substances 0.000 description 3
- 230000002194 synthesizing effect Effects 0.000 description 3
- 238000006482 condensation reaction Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000003287 optical effect Effects 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 238000003786 synthesis reaction Methods 0.000 description 2
- 230000006820 DNA synthesis Effects 0.000 description 1
- 208000020401 Depressive disease Diseases 0.000 description 1
- 238000002835 absorbance Methods 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 150000005690 diesters Chemical class 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 238000003541 multi-stage reaction Methods 0.000 description 1
- 239000002777 nucleoside Substances 0.000 description 1
- 150000003833 nucleoside derivatives Chemical class 0.000 description 1
- OJMIONKXNSYLSR-UHFFFAOYSA-N phosphorous acid Chemical compound OP(O)O OJMIONKXNSYLSR-UHFFFAOYSA-N 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000004064 recycling Methods 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 238000010532 solid phase synthesis reaction Methods 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000001308 synthesis method Methods 0.000 description 1
- 230000032258 transport Effects 0.000 description 1
- 150000005691 triesters Chemical class 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Saccharide Compounds (AREA)
- Devices And Processes Conducted In The Presence Of Fluids And Solid Particles (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10059286A JPS62258737A (ja) | 1986-04-30 | 1986-04-30 | 固相反応装置 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10059286A JPS62258737A (ja) | 1986-04-30 | 1986-04-30 | 固相反応装置 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS62258737A JPS62258737A (ja) | 1987-11-11 |
| JPH0415019B2 true JPH0415019B2 (enrdf_load_stackoverflow) | 1992-03-16 |
Family
ID=14278141
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP10059286A Granted JPS62258737A (ja) | 1986-04-30 | 1986-04-30 | 固相反応装置 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS62258737A (enrdf_load_stackoverflow) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04137733U (ja) * | 1991-06-12 | 1992-12-22 | 京都機械株式会社 | スタテイツクミキサー |
| JP7175740B2 (ja) * | 2018-12-14 | 2022-11-21 | 東レエンジニアリング株式会社 | 薬液合成装置及び薬液合成方法 |
| JP7720171B2 (ja) * | 2021-03-29 | 2025-08-07 | 東レエンジニアリング株式会社 | 薬液合成装置 |
-
1986
- 1986-04-30 JP JP10059286A patent/JPS62258737A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS62258737A (ja) | 1987-11-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US5186824A (en) | System for solid phase reactions | |
| EP1550866A1 (en) | Integrated chemical synthesizers | |
| JP2755350B2 (ja) | 自動合成装置 | |
| US5186898A (en) | Automated polypeptide synthesis apparatus | |
| AU781327C (en) | Method and apparatus for dispensing a liquid into a series of wells | |
| US5447691A (en) | Liquid supplying device for use in physical and chemical apparatus | |
| Lindsey | A retrospective on the automation of laboratory synthetic chemistry | |
| Sindelar et al. | High-throughput DNA synthesis in a multichannel format | |
| JPH0658942A (ja) | 試料液体分析装置及び試料液体分析法 | |
| US5273656A (en) | System for solid phase reactions | |
| WO1992002303A1 (en) | Apparatus for carrying out biochemical reactions | |
| CN1372490A (zh) | 快速筛选多相反应的方法和装置 | |
| US11666882B2 (en) | Bidirectional flow reaction system for solid phase synthesis | |
| JPH0415019B2 (enrdf_load_stackoverflow) | ||
| EP0510487B1 (en) | Automated synthesis apparatus and method of controlling the apparatus | |
| US5272075A (en) | System for solid phase reactions | |
| CN1117613C (zh) | 进行化学反应的装置 | |
| Park et al. | A microchemical system with continuous recovery and recirculation of catalyst-immobilized magnetic particles | |
| WO2004069401B1 (en) | Device and process for the simultaneous agitation of reaction mixtures | |
| US5106585A (en) | Method and apparatus for cleaving deoxyribonucleic acid | |
| EP1174184B1 (en) | Sequential reaction system | |
| WO2000045957A1 (en) | System, method and computer program product for automated fluid or gas delivery | |
| Bartak et al. | Design and construction of the automatic peptide library synthesizer | |
| JP4920301B2 (ja) | Ｒｉ化合物合成装置及びｒｉ化合物合成方法 | |
| SU1650240A1 (ru) | Проточный реактор дл твердофазного синтеза биополимеров |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| LAPS | Cancellation because of no payment of annual fees |