JPH04128651A - Test tool - Google Patents
Test toolInfo
- Publication number
- JPH04128651A JPH04128651A JP2249867A JP24986790A JPH04128651A JP H04128651 A JPH04128651 A JP H04128651A JP 2249867 A JP2249867 A JP 2249867A JP 24986790 A JP24986790 A JP 24986790A JP H04128651 A JPH04128651 A JP H04128651A
- Authority
- JP
- Japan
- Prior art keywords
- support
- water
- test device
- test
- layer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000012360 testing method Methods 0.000 title claims abstract description 83
- 238000001514 detection method Methods 0.000 claims abstract description 25
- 239000007788 liquid Substances 0.000 claims abstract description 25
- 239000000463 material Substances 0.000 claims description 13
- 239000002198 insoluble material Substances 0.000 claims description 8
- 239000002195 soluble material Substances 0.000 claims description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 20
- 238000004090 dissolution Methods 0.000 abstract description 11
- 239000002699 waste material Substances 0.000 abstract 1
- 210000002700 urine Anatomy 0.000 description 10
- 239000003153 chemical reaction reagent Substances 0.000 description 4
- 238000005259 measurement Methods 0.000 description 4
- 210000001124 body fluid Anatomy 0.000 description 3
- 239000010839 body fluid Substances 0.000 description 3
- 206010003445 Ascites Diseases 0.000 description 2
- 239000004372 Polyvinyl alcohol Substances 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 239000003651 drinking water Substances 0.000 description 2
- 235000020188 drinking water Nutrition 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 238000007646 gravure printing Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 229920002451 polyvinyl alcohol Polymers 0.000 description 2
- 210000003296 saliva Anatomy 0.000 description 2
- 238000007650 screen-printing Methods 0.000 description 2
- -1 urine Substances 0.000 description 2
- 238000012795 verification Methods 0.000 description 2
- 239000002351 wastewater Substances 0.000 description 2
- 239000004925 Acrylic resin Substances 0.000 description 1
- 229920000178 Acrylic resin Polymers 0.000 description 1
- IMROMDMJAWUWLK-UHFFFAOYSA-N Ethenol Chemical compound OC=C IMROMDMJAWUWLK-UHFFFAOYSA-N 0.000 description 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 1
- 239000004793 Polystyrene Substances 0.000 description 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 229920000609 methyl cellulose Polymers 0.000 description 1
- 239000001923 methylcellulose Substances 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000010409 thin film Substances 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N31/00—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods
- G01N31/22—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using chemical indicators
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
- G01N33/525—Multi-layer analytical elements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
- G01N33/528—Atypical element structures, e.g. gloves, rods, tampons, toilet paper
Abstract
Description
【発明の詳細な説明】
〈産業上の利用分野〉
本発明は、尿、血液、腹水、せき髄液、唾液などの体液
、あるいは他の液体（飲料水、排水等）の検査に用いら
れる試験具に関するものである。[Detailed Description of the Invention] <Industrial Application Field> The present invention is a test device used for testing body fluids such as urine, blood, ascites, spinal fluid, saliva, or other liquids (drinking water, wastewater, etc.). It is related to.
〈従来の技術〉
従来、例えば、尿などの体液の成分を検査する試験具と
しては、短冊状の支持体の片側面に、各種検査成分と呈
色反応をする検出機能部が設けられているものが知られ
ている。<Prior art> Conventionally, for example, test devices for testing the components of body fluids such as urine have been provided with a detection function section on one side of a strip-shaped support that causes a color reaction with various test components. something is known.
従来の試験具において、支持体を構成する材質としては
、ポリスチレンなどの樹脂のように、適度な剛性と耐水
性を有する材料が利用されている。In conventional test devices, a material having appropriate rigidity and water resistance, such as a resin such as polystyrene, is used as the material constituting the support.
一方、使用済の試験具は、被検液が付着しているので、
そのまま廃棄するには不衛生であり、またこれを媒体と
して他者に病原体が感染する可能性もある。 そこで従
来では、使用済の試験具を、ポリ袋に入れて廃棄したり
、あるいは焼却するなどして処分していた。On the other hand, used test devices have test liquid attached to them, so
It is unsanitary to dispose of it as is, and there is a possibility that pathogens may be transmitted to others through this. Conventionally, used test tools have been disposed of by putting them in a plastic bag and disposing of them, or by incinerating them.
このように、上記処分は極めて煩雑であり、使用後の処
分が容易な試験具が望まれていた。As described above, the above-mentioned disposal is extremely complicated, and a test device that can be easily disposed of after use has been desired.
そこで、出願人は本願に先立ち、特開昭６２−２４１．
４５号公報や、特開平１−１２１．７５２号公報に記載
されているような、支持体が水に溶け、使用後は水洗便
器などに投棄できる試験具を提案している。Therefore, prior to filing the present application, the applicant filed the application in Japanese Unexamined Patent Publication No. 62-241.
No. 45 and JP-A-1-121.752 have proposed test devices in which the support is soluble in water and can be disposed of in a flush toilet after use.
しかし、これらの公報に記載されている試験具は、支持
体の表面が例えばボワビニルアルコールなどの水溶性材
料となっており、水に濡れると、完全に溶解するまでは
粘着状態となる。 従って、例えば水洗の便器などに投
棄して処分すると、便器の内壁に付着して、水を流して
も除去されず、便器の汚れがひどくなるといった問題が
あった。However, in the test devices described in these publications, the surface of the support is made of a water-soluble material such as bois vinyl alcohol, and when it gets wet with water, it becomes sticky until it completely dissolves. Therefore, when disposed of by dumping it into a toilet bowl, for example, it adheres to the inner wall of the toilet bowl and is not removed even when flushed with water, resulting in a problem that the toilet bowl becomes extremely dirty.
特開平１−１２１７５２号公報の試験具では、溶解速度
が速すぎるため、支持体が、被検液との接触の後、検出
機能部の反応観察や反応測定等が終了するまでの間に、
ロール状に変形してしまうことがある。 これにより、
検出機能部を支持するという支持体本来の役割を十分果
すことができない場合が有った。 特に、このような変
形が生ずると、試験具を測定機器内にセットして判定す
ることが困難となる。In the test device disclosed in JP-A No. 1-121752, the dissolution rate is too fast, so that after the support comes into contact with the test liquid, until reaction observation and reaction measurement of the detection function section are completed,
It may deform into a roll shape. This results in
There were cases in which the support could not sufficiently fulfill its original role of supporting the detection function section. In particular, when such deformation occurs, it becomes difficult to set the test tool in a measuring instrument and make a determination.
出願人は、さらに、特開平１−１２１７５２号公報の試
験具の支持体の溶解速度を抑制するため、特願平０１−
２６９１６１号にて、上記支持体の表面に薄膜の水不溶
性材料を被着した試験具を提案している。The applicant further proposed Japanese Patent Application No. 01-121752 in order to suppress the dissolution rate of the support of the test device of JP-A-1-121752.
No. 269161 proposes a test device in which a thin film of a water-insoluble material is deposited on the surface of the support.
しかし、前記試験具では、可溶部分が溶けた後も水中に
水不溶性材料が残るため、下水管の詰まりの原因となっ
たり、水不溶性材料のみが便器の内壁に付着して残留す
るといった問題があった。However, with these test devices, water-insoluble materials remain in the water even after the soluble portion has dissolved, resulting in problems such as clogging of sewer pipes and only water-insoluble materials remaining on the inner wall of the toilet bowl. was there.
〈発明が解決しようとする課題〉
本発明の目的は、上述した従来技術の欠点を解消し、被
検液との接触の後も、検査終了迄は一定の剛性を保ち、
水中に投棄した後は直ちに溶解して分散する試験具を提
供することにある。<Problems to be Solved by the Invention> The purpose of the present invention is to solve the above-mentioned drawbacks of the prior art, maintain a constant rigidity even after contact with the test liquid until the end of the test, and
The object of the present invention is to provide a test device that immediately dissolves and disperses after being dumped into water.
く課題を解決するための手段〉
このような目的は、下記（１）〜（７）の本発明によっ
て達成される。 即ち、
（１）板状の支持体と、該支持体上に配設された検出機
能部とを有する試験具において、前記支持体は、崩壊層
と、該崩壊層の少なくとも一方の面に被着されている溶
解層とを有し、前記支持体の両表面には水不溶性材料か
らなる微小片を多数被着したことを特徴とする試験具。Means for Solving the Problems> Such objects are achieved by the following inventions (1) to (7). (1) In a test device having a plate-shaped support and a detection function section disposed on the support, the support includes a disintegration layer and at least one surface of the disintegration layer. 1. A test device characterized in that the support has a dissolving layer attached thereto, and a large number of minute pieces made of a water-insoluble material are attached to both surfaces of the support.
（２）前記崩壊層は水崩壊性材料よりなり、前記溶解層
は前記水崩壊性材料に遅れて溶解する水溶性材料からな
る上記（１）に記載の試験具・
（３）前記支持体は、被検液と接触した後、前記検出機
能部での検出が実質的に終了するまでその支持機能を維
持しうるものである上記（１）または（２）に記載の試
験具。(2) The test device according to (1) above, wherein the disintegrating layer is made of a water-disintegrating material, and the dissolving layer is made of a water-soluble material that dissolves with a delay in the water-disintegrating material. (3) The support is . The test device according to (1) or (2) above, which is capable of maintaining its supporting function after contact with the test liquid until the detection in the detection function section is substantially completed.
（４）前記微小片の形状を矩形とし、支持体の表面に規
則的に配列した上記（１）〜（３）のいずれかに記載の
試験具。(4) The test device according to any one of (1) to (3) above, wherein the minute pieces have a rectangular shape and are regularly arranged on the surface of a support.
（５）前記微小片の厚さは１〜１５−程度である上記（
１）〜（４）のいずれかに記載の試験具・
（６）一つの前記微小片の面積は、０．１６〜０．６４
ｍｍ２程度である上記（１）〜（５）のいずれかに記載
の試験具。(5) The thickness of the minute pieces is about 1 to 15 - (
The test device according to any one of 1) to (4) (6) The area of one of the minute pieces is 0.16 to 0.64.
The test device according to any one of (1) to (5) above, which has a size of about mm2.
（７）支持体の総表面積に対する前記微小片の合計面積
の割合が３０〜８０％程度である上記（１）〜（６）の
いずれかに記載の試験具。(7) The test device according to any one of (1) to (6) above, wherein the ratio of the total area of the minute pieces to the total surface area of the support is about 30 to 80%.
〈作用〉
支持体を把持しつつ、検出機能部に被検液を接触させ、
検出機能部の反応強度を判定する。<Operation> While holding the support, bring the test liquid into contact with the detection function part,
Determine the reaction strength of the detection function section.
支持体は、検出機能部の判定を完了させる迄のあいだは
一定の剛性を維持することにより、検出機能部を支持す
る。The support body supports the detection function section by maintaining a constant rigidity until the detection function section completes the determination.
判定が終了した後は、試験具を任意の漬水中に投棄して
処分する。 この際、支持体を構成する溶解層は崩壊層
に重ねて設けられ、前記判定が終了する迄は、水崩壊性
材料からなる崩壊層の変形による支持体の変形を抑制す
る。 また、支持体の表面に被着された微小片は、その
被着された面積密度を変えることができる。After the determination is complete, dispose of the test device by dumping it in any immersion water. At this time, the dissolving layer constituting the support is provided to overlap the disintegrating layer, and until the above determination is completed, deformation of the support due to deformation of the disintegrating layer made of a water-disintegratable material is suppressed. Furthermore, the micropieces deposited on the surface of the support can vary in their deposited areal density.
そして、該微小片は処理溶解液と支持体との接触面積を
少なくして、支持体の溶解を抑制する。 また、微小片
は水溶性材料からなる溶解層の表面に被着されているの
で、粘着賀状に溶解した溶解層が、例えば下水管内壁等
の周囲物体に張り付（ことはない。 微小片を矩形とし
、規則正しく配列すれば、微小片の被着等の処理が容易
となり、コストの低減が図られる。The fine pieces reduce the contact area between the treatment solution and the support, thereby suppressing dissolution of the support. In addition, since the minute particles are adhered to the surface of the dissolved layer made of water-soluble material, the dissolved layer dissolved in the adhesive card will not stick to surrounding objects such as the inner wall of a sewer pipe. If they are rectangular and arranged regularly, processing such as adhesion of minute pieces becomes easy, and costs can be reduced.
また、微小片の厚さは薄い程よいが微小片の被着方法に
よっては厚さが１〜１５７１３１程度でよい。Further, the thinner the thickness of the micropiece, the better, but depending on the method of adhering the micropiece, the thickness may be about 1 to 157,131 mm.
支持体の総表面積に対する微小片の合計面積の割合を変
えれば、支持体の溶解速度（溶解時間）を調節すること
ができる。By changing the ratio of the total area of minute particles to the total surface area of the support, the dissolution rate (dissolution time) of the support can be adjusted.
〈実施例〉
以下本発明の好適実施例について、図面に基いて詳説す
る。 第２図には、本発明の一例を示す試験具１の全体
斜視図が示されている。<Embodiments> Preferred embodiments of the present invention will be described in detail below with reference to the drawings. FIG. 2 shows an overall perspective view of the test device 1 showing an example of the present invention.
図示されている一実施例としての試験具１は、被検液と
して尿を対象としている。 試験具１は、板状の支持体
２と、該支持体２の片面に取り付けられた検出機能部３
とから構成されている。The illustrated test device 1 as an example uses urine as a test liquid. The test device 1 includes a plate-shaped support 2 and a detection function section 3 attached to one side of the support 2.
It is composed of.
検出機能部３は、例えば濾紙に検査試薬を含浸させて作
られるもので、検出する成分によって前記検査試薬の種
類が異なる。 図示されている試験具１は、このほか検
出機能部３を複数設けた構成としても良い。 本実施例
において用いられる試薬では１例えば蛋白質を検出する
試薬が用いられる。The detection function section 3 is made by impregnating a filter paper with a test reagent, for example, and the type of the test reagent varies depending on the component to be detected. The illustrated test device 1 may also have a configuration in which a plurality of detection function sections 3 are provided. Among the reagents used in this example, for example, a reagent for detecting proteins is used.
次に、支持体２の構成について説明すると、支持体２は
図示されているように、板状に形成されている。 該支
持体２は第１図に示されるように、後述する幾つかの層
を有し、表裏両面には所定密度で微小片６が被着されて
いる。Next, the structure of the support body 2 will be explained. The support body 2 is formed into a plate shape as shown in the figure. As shown in FIG. 1, the support 2 has several layers to be described later, and minute pieces 6 are adhered to both the front and back surfaces at a predetermined density.
支持体２は崩壊層５０と、該崩壊層５０の表裏面に積層
された溶解層５１を有している。The support 2 has a disintegrating layer 50 and dissolving layers 51 laminated on the front and back surfaces of the disintegrating layer 50.
崩壊層５０は水との接触によって、その形状が崩壊し、
不溶要素が水中に分散する水崩壊性材料からなっている
。 水崩壊性材料の例としては、バルブ、セルロース等
の水不溶性材料を、例えばカルボキシメチルセルロース
ナトリウム（ＣＭＣ−Ｎａ）やメチルセルロース等の水
溶性材料でシート状に固めたものが挙げられる。The collapse layer 50 collapses in shape upon contact with water,
It consists of a water-disintegratable material in which the insoluble elements are dispersed in water. Examples of water-disintegratable materials include bulbs, cellulose, and other water-insoluble materials solidified into a sheet shape with water-soluble materials such as sodium carboxymethylcellulose (CMC-Na) and methylcellulose.
本実施例の支持体２の崩壊層５０としては水溶紙が利用
され、例えば三島製紙社製の製品名ディゾルボが使用さ
れる。A water-soluble paper is used as the disintegrating layer 50 of the support 2 in this embodiment, and for example, a product named Disorbo manufactured by Mishima Paper Co., Ltd. is used.
溶解層５１をなす水溶性材料としては、例えば、ポリビ
ニルアルコール、ポリエチレンオキサイドなどが挙げら
れる。 本実施例の試験具１では、ポリビニルアルコー
ルが用いられている。 溶解層５１はある程度の剛性を
有し、支持体２が尿に接触してから検出機能部３の呈色
判定が終了するまでは、その剛性は維持される。 従っ
て、前記崩壊層５０が例えば尿と接触すると、水崩壊性
材料の崩壊が生ずるが、前記水崩壊性材料の崩壊に遅れ
て、前記水溶性材料が溶解するため、前記支持体２の形
状は水溶性材料がある程度溶けるまで、変形せずに維持
される。Examples of the water-soluble material forming the dissolving layer 51 include polyvinyl alcohol and polyethylene oxide. In the test device 1 of this example, polyvinyl alcohol is used. The dissolving layer 51 has a certain degree of rigidity, and this rigidity is maintained from the time the support 2 comes into contact with urine until the color determination by the detection function section 3 is completed. Therefore, when the disintegrating layer 50 comes into contact with, for example, urine, the water-disintegrating material disintegrates, but the water-soluble material dissolves after the disintegration of the water-disintegrating material, so that the shape of the support 2 is It remains undeformed until the water-soluble material dissolves to some extent.
つまり、尿と接触させた試験具１には、検出機能部３の
周囲に尿が付着しているが、この付着している尿の量で
は、溶解または変形しない程度の剛性を保ち得る厚さを
有していればよい。In other words, the test device 1 that has been brought into contact with urine has urine attached to the area around the detection function section 3, but with the amount of urine attached, the thickness is sufficient to maintain rigidity to the extent that it does not dissolve or deform. It is sufficient if it has the following.
検査が終了した試験具１は、水中に投棄される。 検査
が終了した試験具１は、水中で溶解して分散するまでの
時間は、崩壊層５０と溶解層５１の厚さの比率によって
調節することができる。 本実施例の試験具１における
一例を示すと、崩壊層５０が２２０戸、溶解層５１が３
０−である。 このほか、崩壊層５０と溶解層５１をそ
れぞれ１層づつとしてもよい。After the test, the test device 1 is discarded into water. The time required for the tested test device 1 to dissolve and disperse in water can be adjusted by adjusting the ratio of the thicknesses of the disintegrating layer 50 and the dissolving layer 51. To show an example of the test device 1 of this embodiment, there are 220 disintegrating layers 50 and 3 dissolving layers 51.
It is 0-. In addition, the disintegration layer 50 and the dissolution layer 51 may each have one layer.
支持体２の表裏面に被着される微小片６は第１図に示さ
れているように、正方形の微小片であり、一定の間隙を
介して縦横に等間隔に被着されている。 微小片６の材
質は、水不溶性材料であればよく、例えばアクリル樹脂
が用いられるが、この他、見栄えをよくするため、顔料
を添加し、着色してもよい。As shown in FIG. 1, the minute pieces 6 attached to the front and back surfaces of the support body 2 are square minute pieces, and are attached at equal intervals vertically and horizontally with a certain gap in between. The material of the minute pieces 6 may be any water-insoluble material, for example, acrylic resin is used, but in addition to this, pigments may be added and colored to improve the appearance.
該微小片６の被着部分は、微小片６によって溶解層５１
と水または被検液との接触が妨げられる。 よって、支
持体２の総表面積に対する全微小片６の合計面積の割合
によっても、支持体２の水中溶解時間を調節できる。The adhered portion of the minute pieces 6 is covered with a dissolved layer 51 by the minute pieces 6.
contact with water or test liquid is prevented. Therefore, the dissolution time of the support 2 in water can also be adjusted by adjusting the ratio of the total area of all the fine pieces 6 to the total surface area of the support 2.
微小片６は、例えばスクリーン印刷やグラビア印刷によ
って支持体２の表裏両面に被着される。The minute pieces 6 are applied to both the front and back surfaces of the support 2 by, for example, screen printing or gravure printing.
また、微小片６の厚さは１〜１５−程度であるが、薄け
れば薄い程良い。Further, the thickness of the minute piece 6 is about 1 to 15 -, but the thinner the better.
例えばスクリーン印刷による場合の微小片６の厚さは、
５〜１５−程度、グラビア印刷による場合の厚さは１〜
１０ｐ程度でよい。 また、本実施例の試験具１では５
層程度である。For example, the thickness of the minute piece 6 in the case of screen printing is
Approximately 5 to 15 mm, thickness by gravure printing is 1 to 15 mm.
About 10p is sufficient. In addition, in the test device 1 of this example, 5
It's about a layer.
さらに、微小片６の一辺は本実施例の試験具１では０．
８ｏ＋ｍ程度であり、従って、微小片１個の面積は０．
６４ｍｍ”程度である。 支持体２の表裏面に被着され
たすべての微小片６の合計面積は、５２４．８ｍｍ″で
あり、支持体２の総表面積の６０％程度である。Furthermore, one side of the minute piece 6 is 0.0 mm in the test device 1 of this embodiment.
It is about 8o+m, so the area of one minute piece is 0.
The total area of all the fine pieces 6 attached to the front and back surfaces of the support 2 is 524.8 mm'', which is about 60% of the total surface area of the support 2.
既に述べたように、支持体２が被検液と接触したのち、
一定の剛性を保って、支持機能を維持しつる時間、およ
び水中に投棄してから溶解分離するまでの時間は、既述
した崩壊層５０と溶解層５１との厚さの割合、および、
支持体２の総表面積に対する微小片６の合計面積の割合
によって調節することができる。As already mentioned, after the support 2 comes into contact with the test liquid,
The time it takes to maintain a certain rigidity and support function, and the time from when it is dumped into water until it is dissolved and separated, are determined by the ratio of the thicknesses of the disintegrating layer 50 and the dissolving layer 51 described above, and
It can be adjusted by changing the ratio of the total area of the micro pieces 6 to the total surface area of the support 2.
ところで、試験具１の性質としては、被検液に接触させ
たのち反応観察や反応測定が終了するまでは、前記観察
や測定が可能となる程度に剛性を維持し、水中に投棄し
た後は速やかに溶解分散するものであることが望まれる
。By the way, the properties of the test device 1 are that it maintains its rigidity to the extent that the observation and measurement are possible after it has been brought into contact with the test liquid until the reaction observation and reaction measurement are completed, and that it maintains its rigidity to the extent that the above-mentioned observation and measurement are possible. It is desirable that it dissolves and disperses quickly.
このような性質の試験具を得るためには、例えば、崩壊
層５０に対する溶解層５１の比率を１〜４０％程度とし
、支持体２の総表面積に対する微小片６の合計面積の割
合を３０〜８０％程度とすればよく、より好ましくは、
前記比率を５〜２５％程度、前記割合を４０〜６０％程
度とするのがよい。In order to obtain a test device with such properties, for example, the ratio of the dissolving layer 51 to the disintegrating layer 50 is set to about 1 to 40%, and the ratio of the total area of minute pieces 6 to the total surface area of the support 2 is set to about 30 to 40%. It may be about 80%, and more preferably,
The ratio is preferably about 5 to 25%, and the ratio is preferably about 40 to 60%.
なお、これらの値は、崩壊層５０や溶解層５１に用いら
れる材料によって異なる。Note that these values differ depending on the materials used for the collapsing layer 50 and the dissolving layer 51.
以上のように構成された試験具１の作用を説明する。
試験具１の検出機能部３に被検液たる尿を接触させる。The operation of the test device 1 configured as above will be explained.
The detection function section 3 of the test device 1 is brought into contact with urine as the test liquid.
検出機能部３は、被検液との接触によって反応し、被
検体の有無または濃度を示唆する。 このとき、支持体
２は微小片６によって、被検液との接触面積が制限され
ており、また検出機能部３の反応強度を検定等する場合
には、検出機能部３の周囲に被検液が付着している程度
であるため、支持体２の変形や溶解は微小片６によって
十分抑制される。The detection function section 3 reacts upon contact with the test liquid and suggests the presence or absence or concentration of the test substance. At this time, the contact area of the support 2 with the test liquid is limited by the minute pieces 6, and when testing the reaction strength of the detection function part 3, the support body 2 has a limited contact area with the test liquid. Since the liquid is only attached to the support body 2, deformation and dissolution of the support body 2 are sufficiently suppressed by the minute pieces 6.
すなわち、検出機能部３の検定等が終了する間で、具体
的には５分程度は、自重によって折れ曲らない程度の支
持体２の剛性は維持されている。That is, the rigidity of the support body 2 is maintained to the extent that it does not bend under its own weight for about 5 minutes, specifically, while the verification of the detection function section 3 is completed.
検出機能部３の検定が終了した後、試験具１を、例えば
水洗用の便器等に廃棄すると、微小片６の間隙７および
板状の支持体２の端辺から水分が浸入して、崩壊層５０
や溶解層５１を溶かし始め、２分程度で完全に溶解する
。 ここで、微小片６は規則正しく等間隔で配列されて
いるため、支持体２は全体が均一に溶解する。If the test device 1 is disposed of, for example, in a toilet bowl after the verification of the detection function section 3 is completed, moisture will enter through the gaps 7 of the minute pieces 6 and the edges of the plate-shaped support 2, causing it to disintegrate. layer 50
The melted layer 51 starts to melt and is completely dissolved in about 2 minutes. Here, since the minute pieces 6 are regularly arranged at equal intervals, the entire support body 2 is uniformly dissolved.
溶解層５１は、溶解の過程で粘着質となるが、表面には
微小片６が被着されているため、便器の内壁に張り付く
等の問題は生じない。The dissolving layer 51 becomes sticky during the dissolution process, but since the fine pieces 6 are adhered to the surface, problems such as sticking to the inner wall of the toilet bowl do not occur.
また、支持体２が完全に溶解した後は、各微小片６は水
中に拡散するが、各微小片６毎の大きさは小さいので、
流れやすく、また便器の内壁に付着してもあまり目立た
ない。Furthermore, after the support 2 is completely dissolved, each minute piece 6 diffuses into the water, but since the size of each minute piece 6 is small,
It flows easily and is not very noticeable even if it adheres to the inner wall of the toilet bowl.
なお、微小片６の形状は矩形のものに限らず、ドツト状
や円形のもの、その他の形状としてもよい。Note that the shape of the minute pieces 6 is not limited to a rectangular shape, but may be dot-shaped, circular, or other shapes.
以上説明した実施例は、被検液として尿を対象としてい
るが、このほか血液、腹水、せき髄液、唾液などの体液
、あるいは他の液体（飲料水、排水等）の検査に用いら
れる試験具に利用してもよい。In the embodiments described above, urine is used as the test liquid, but test devices can also be used to test body fluids such as blood, ascites, spinal fluid, saliva, or other liquids (drinking water, wastewater, etc.). It may be used for
〈発明の効果〉
以上説明したように、本発明の試験具によれば、被検液
との接触の後も、検査終了迄は一定の剛性を保ち、水中
に投棄した後は直ちに溶解して分散する。 このため、
廃棄処理が容易で、かつ水中で溶解した後には流動性が
良く、下水管の詰まり等の問題が解決された。<Effects of the Invention> As explained above, according to the test device of the present invention, even after contact with the test liquid, it maintains a certain rigidity until the end of the test, and dissolves immediately after being disposed of in water. Spread. For this reason,
It is easy to dispose of, has good fluidity after being dissolved in water, and solves problems such as clogging of sewer pipes.
第１図は、支持体の部分拡大斜視図である。 第２図は、試験具の全体図である。 符号の説明 １・・・試験具 ２・・・支持体 ３・・・検出機能部 ５０・・・崩壊層 ５１・・・溶解層 ６・・・微小片 ７・・・間隙 FIG. 1 is a partially enlarged perspective view of the support. FIG. 2 is an overall view of the test device. Explanation of symbols 1...Test tool 2...Support 3...Detection function section 50...collapse layer 51...dissolved layer 6...Minute pieces 7... Gap
Claims (7)
能部とを有する試験具において、 前記支持体は、崩壊層と、該崩壊層の少なくとも一方の
面に被着されている溶解層とを有し、前記支持体の両表
面には水不溶性材料からなる微小片を多数被着したこと
を特徴とする試験具。(1) A test device having a plate-shaped support and a detection function section disposed on the support, wherein the support is attached to a disintegration layer and at least one surface of the disintegration layer. 1. A test device comprising: a dissolving layer containing a water-insoluble material; and a large number of minute pieces made of a water-insoluble material are adhered to both surfaces of the support.
は前記水崩壊性材料に遅れて溶解する水溶性材料からな
る請求項１に記載の試験具。(2) The test device according to claim 1, wherein the disintegrating layer is made of a water-disintegrating material, and the dissolving layer is made of a water-soluble material that dissolves behind the water-disintegrating material.
能部での検出が実質的に終了するまでその支持機能を維
持しうるものである請求項１または２のいずれかに記載
の試験具。(3) The support is capable of maintaining its support function after contact with the test liquid until the detection in the detection function section is substantially completed. test equipment.
則的に配列した請求項１〜３のいずれかに記載の試験具
。(4) The test device according to any one of claims 1 to 3, wherein the minute pieces have a rectangular shape and are regularly arranged on the surface of the support.
項１〜４のいずれかに記載の試験具。(5) The test device according to any one of claims 1 to 4, wherein the minute piece has a thickness of about 1 to 15 μm.
ｍｍ＾２程度である請求項１〜５のいずれかに記載の試
験具。(6) The area of one minute piece is 0.16 to 0.64
The test device according to any one of claims 1 to 5, which has a diameter of about mm^2.
の割合が３０〜８０％程度である請求項１〜６のいずれ
かに記載の試験具。(7) The test device according to any one of claims 1 to 6, wherein the ratio of the total area of the minute pieces to the total surface area of the support is about 30 to 80%.
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2249867A JPH0810218B2 (en) | 1990-09-19 | 1990-09-19 | Test tool |
| AU84532/91A AU634909B2 (en) | 1990-09-19 | 1991-09-17 | Testing device |
| US07/761,495 US5244631A (en) | 1990-09-19 | 1991-09-18 | Testing device |
| DE69106290T DE69106290T2 (en) | 1990-09-19 | 1991-09-19 | Test device. |
| EP91402502A EP0477105B1 (en) | 1990-09-19 | 1991-09-19 | Testing device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2249867A JPH0810218B2 (en) | 1990-09-19 | 1990-09-19 | Test tool |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH04128651A true JPH04128651A (en) | 1992-04-30 |
| JPH0810218B2 JPH0810218B2 (en) | 1996-01-31 |
Family
ID=17199372
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2249867A Expired - Lifetime JPH0810218B2 (en) | 1990-09-19 | 1990-09-19 | Test tool |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US5244631A (en) |
| EP (1) | EP0477105B1 (en) |
| JP (1) | JPH0810218B2 (en) |
| AU (1) | AU634909B2 (en) |
| DE (1) | DE69106290T2 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH09138232A (en) * | 1995-11-15 | 1997-05-27 | Terumo Corp | Test piece |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5326707A (en) * | 1991-11-29 | 1994-07-05 | Miles Inc. | Composition and device for urinary protein assay and method of using the same |
| US5516697A (en) * | 1993-08-26 | 1996-05-14 | Ferrosensor, Inc. | Biosensor for detecting iron |
| US5925318A (en) * | 1993-08-26 | 1999-07-20 | Ferro Sensor, Inc. | Iron detecting sensors |
| IL108159A (en) * | 1993-12-23 | 1998-02-08 | Orgenics Ltd | Apparatus for separation, concentration and detection of target molecules in liquid sample |
| US7148070B2 (en) * | 2003-01-24 | 2006-12-12 | Minter Jimmy C | Diagnostic detection method |
| WO2006098804A2 (en) | 2005-03-11 | 2006-09-21 | Chembio Diagnostic Systems, Inc. | Dual path immunoassay device |
| US7189522B2 (en) | 2005-03-11 | 2007-03-13 | Chembio Diagnostic Systems, Inc. | Dual path immunoassay device |
| US8012761B2 (en) * | 2006-12-14 | 2011-09-06 | Kimberly-Clark Worldwide, Inc. | Detection of formaldehyde in urine samples |
| US7846383B2 (en) * | 2006-12-15 | 2010-12-07 | Kimberly-Clark Worldwide, Inc. | Lateral flow assay device and absorbent article containing same |
| US20100022916A1 (en) | 2008-07-24 | 2010-01-28 | Javanbakhsh Esfandiari | Method and Apparatus for Collecting and Preparing Biological Samples for Testing |
| US8603835B2 (en) | 2011-02-10 | 2013-12-10 | Chembio Diagnostic Systems, Inc. | Reduced step dual path immunoassay device and method |
| CA2944488C (en) | 2014-04-02 | 2023-03-21 | Chembio Diagnostic Systems, Inc. | Immunoassay utilizing trapping conjugate |
| US20160116466A1 (en) | 2014-10-27 | 2016-04-28 | Chembio Diagnostic Systems, Inc. | Rapid Screening Assay for Qualitative Detection of Multiple Febrile Illnesses |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS50117152A (en) * | 1974-02-27 | 1975-09-12 | ||
| JPS63218863A (en) * | 1987-03-09 | 1988-09-12 | Dainippon Printing Co Ltd | Body fluid examination material |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4578358A (en) * | 1983-05-03 | 1986-03-25 | Warner-Lambert Company | Collection of specimens and detection of occult blood therein |
| US4673654A (en) * | 1985-10-31 | 1987-06-16 | Warner-Lambert Company | Composition for determining peroxidase-like activity of hemoglobin |
| JPH02296152A (en) * | 1989-05-11 | 1990-12-06 | Hidenobu Akutsu | Paper for detecting and indicating diseased condition |
-
1990
- 1990-09-19 JP JP2249867A patent/JPH0810218B2/en not_active Expired - Lifetime
-
1991
- 1991-09-17 AU AU84532/91A patent/AU634909B2/en not_active Ceased
- 1991-09-18 US US07/761,495 patent/US5244631A/en not_active Expired - Fee Related
- 1991-09-19 EP EP91402502A patent/EP0477105B1/en not_active Expired - Lifetime
- 1991-09-19 DE DE69106290T patent/DE69106290T2/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS50117152A (en) * | 1974-02-27 | 1975-09-12 | ||
| JPS63218863A (en) * | 1987-03-09 | 1988-09-12 | Dainippon Printing Co Ltd | Body fluid examination material |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH09138232A (en) * | 1995-11-15 | 1997-05-27 | Terumo Corp | Test piece |
Also Published As
| Publication number | Publication date |
|---|---|
| EP0477105B1 (en) | 1994-12-28 |
| DE69106290D1 (en) | 1995-02-09 |
| US5244631A (en) | 1993-09-14 |
| EP0477105A1 (en) | 1992-03-25 |
| AU8453291A (en) | 1992-03-26 |
| AU634909B2 (en) | 1993-03-04 |
| JPH0810218B2 (en) | 1996-01-31 |
| DE69106290T2 (en) | 1995-05-18 |
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