JPH0371440B2 - - Google Patents

Info

Publication number
JPH0371440B2
JPH0371440B2 JP1217176A JP21717689A JPH0371440B2 JP H0371440 B2 JPH0371440 B2 JP H0371440B2 JP 1217176 A JP1217176 A JP 1217176A JP 21717689 A JP21717689 A JP 21717689A JP H0371440 B2 JPH0371440 B2 JP H0371440B2
Authority
JP
Japan
Prior art keywords
benzyl
deoxy
formula
twenty
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP1217176A
Other languages
English (en)
Japanese (ja)
Other versions
JPH02138290A (ja
Inventor
Eichi Joonzu Goodon
Jii Mofuato Jon
Jei Nesutaa Junia Jon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntex USA LLC
Original Assignee
Syntex USA LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/680,618 external-priority patent/US4082736A/en
Priority claimed from US05/680,260 external-priority patent/US4082735A/en
Application filed by Syntex USA LLC filed Critical Syntex USA LLC
Publication of JPH02138290A publication Critical patent/JPH02138290A/ja
Publication of JPH0371440B2 publication Critical patent/JPH0371440B2/ja
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K9/00Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
JP1217176A 1976-04-26 1989-08-23 新規な免疫アジュバント化合物およびその製造方法 Granted JPH02138290A (ja)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US05/680,618 US4082736A (en) 1976-04-26 1976-04-26 Novel immunological adjuvant compounds and methods of preparation thereof
US680618 1976-04-26
US680260 1976-04-26
US05/680,260 US4082735A (en) 1976-04-26 1976-04-26 Novel immunological adjuvant compounds and methods of preparation thereof
US77720477A 1977-03-14 1977-03-14
US777204 1977-03-14

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP62233620A Division JPS6399097A (ja) 1976-04-26 1987-09-17 新規な免疫アジュバント化合物およびその製造方法

Publications (2)

Publication Number Publication Date
JPH02138290A JPH02138290A (ja) 1990-05-28
JPH0371440B2 true JPH0371440B2 (fr) 1991-11-13

Family

ID=27418368

Family Applications (2)

Application Number Title Priority Date Filing Date
JP4777777A Granted JPS52131526A (en) 1976-04-26 1977-04-25 New compound of immunological adjuvant and method of preparation
JP1217176A Granted JPH02138290A (ja) 1976-04-26 1989-08-23 新規な免疫アジュバント化合物およびその製造方法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP4777777A Granted JPS52131526A (en) 1976-04-26 1977-04-25 New compound of immunological adjuvant and method of preparation

Country Status (8)

Country Link
JP (2) JPS52131526A (fr)
CH (1) CH636887A5 (fr)
DE (1) DE2718010A1 (fr)
ES (1) ES458197A1 (fr)
FR (1) FR2349600A1 (fr)
GB (1) GB1571133A (fr)
NL (1) NL7704555A (fr)
SE (1) SE445924B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0002677B1 (fr) * 1977-12-02 1982-10-13 Takeda Chemical Industries, Ltd. Dérivés de glucosamine-peptides et leurs compositions pharmaceutiques
FR2420545A1 (fr) * 1978-03-20 1979-10-19 Anvar Nouveaux esters de l'acide n-acetyl-muramyl-aminoacyl-glutamique ou des derives de substitution de celui-ci a proprietes anti-infectieuses et/ou d'adjuvants immunologiques
FR2442241A2 (fr) * 1978-03-20 1980-06-20 Anvar Nouveaux composes esters de muramyl-peptide, leur preparation et les compositions pharmaceutiques les contenant, notamment sous forme de liposomes
US4335111A (en) * 1978-12-22 1982-06-15 Agence National De Valorisation De La Recherche (Anvar) Compounds associating peptidyl of aminoacyl residues to lipophilic groups and pharmaceutical compositions containing said new compounds
US4256735A (en) * 1979-01-29 1981-03-17 Merck & Co., Inc. Immunologically active dipeptidyl saccharides and methods of preparation
FR2449697A1 (fr) * 1979-02-20 1980-09-19 Anvar Nouveaux muramyl-peptides substitues sur un azote peptidique et medicaments les contenant
CA1185237A (fr) * 1979-02-28 1985-04-09 Yuichi Yamamura Derives de 6 desoxyglucosamine-peptide; preparation et utilisation
FR2482957A2 (fr) * 1979-06-29 1981-11-27 Rhone Poulenc Ind Nouveaux dipeptides, leur preparation et les medicaments qui les contiennent
US4406889A (en) * 1980-02-15 1983-09-27 Ciba-Geigy Corporation Derivatives of aldohexoses, intermediates, processes for their manufacture, preparations containing such compounds, and their use
US4368190A (en) * 1980-04-17 1983-01-11 Merck & Co., Inc. Immunologically active dipeptidyl 4-O-,6-O-acyl-2-amino-2-deoxy-D-glucose derivatives and methods for their preparation
JPS6042398A (ja) * 1983-08-18 1985-03-06 Toshiyuki Hamaoka ムラミルジペプチド活性エステル誘導体
US4777160A (en) * 1986-09-18 1988-10-11 Bristol-Myers BU-2867T peptide antibiotics
US10927147B2 (en) 2015-12-10 2021-02-23 Bharat Biotech International Limited Muramyl peptide derivative compound, synthesis and uses thereof
WO2017103944A1 (fr) 2015-12-15 2017-06-22 Bharat Biotech International Limited Nouveau composé dérivé des peptides de muramyle, sa synthèse et ses utilisations

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH613709A5 (en) * 1975-12-10 1979-10-15 Ciba Geigy Ag Process for the preparation of glucosamine derivatives

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BULL.CHEM.SOC.JAN.=1976 *

Also Published As

Publication number Publication date
FR2349600A1 (fr) 1977-11-25
CH636887A5 (en) 1983-06-30
SE7704609L (sv) 1977-10-27
JPS52131526A (en) 1977-11-04
JPS638119B2 (fr) 1988-02-19
NL7704555A (nl) 1977-10-28
SE445924B (sv) 1986-07-28
GB1571133A (en) 1980-07-09
FR2349600B1 (fr) 1981-01-02
JPH02138290A (ja) 1990-05-28
DE2718010C2 (fr) 1990-11-08
DE2718010A1 (de) 1977-11-10
ES458197A1 (es) 1978-08-16

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