JPH0346783B2 - - Google Patents
Info
- Publication number
- JPH0346783B2 JPH0346783B2 JP58192301A JP19230183A JPH0346783B2 JP H0346783 B2 JPH0346783 B2 JP H0346783B2 JP 58192301 A JP58192301 A JP 58192301A JP 19230183 A JP19230183 A JP 19230183A JP H0346783 B2 JPH0346783 B2 JP H0346783B2
- Authority
- JP
- Japan
- Prior art keywords
- column
- piston
- fluid
- arm
- chamber
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000012530 fluid Substances 0.000 claims description 42
- 230000006835 compression Effects 0.000 claims description 34
- 238000007906 compression Methods 0.000 claims description 34
- 238000004587 chromatography analysis Methods 0.000 claims description 31
- 238000012856 packing Methods 0.000 claims description 18
- 230000005540 biological transmission Effects 0.000 claims description 3
- 230000003247 decreasing effect Effects 0.000 claims description 3
- 238000007599 discharging Methods 0.000 claims description 2
- 238000006073 displacement reaction Methods 0.000 claims description 2
- 238000005192 partition Methods 0.000 claims 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 24
- 239000000377 silicon dioxide Substances 0.000 description 11
- 238000009826 distribution Methods 0.000 description 9
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 8
- 239000000126 substance Substances 0.000 description 6
- 230000032258 transport Effects 0.000 description 6
- 229920001971 elastomer Polymers 0.000 description 5
- 239000007788 liquid Substances 0.000 description 5
- 235000011187 glycerol Nutrition 0.000 description 4
- 238000011144 upstream manufacturing Methods 0.000 description 4
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- 229910000831 Steel Inorganic materials 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 238000007789 sealing Methods 0.000 description 3
- 238000000926 separation method Methods 0.000 description 3
- 239000010959 steel Substances 0.000 description 3
- 229910000906 Bronze Inorganic materials 0.000 description 2
- 239000004698 Polyethylene Substances 0.000 description 2
- 239000010974 bronze Substances 0.000 description 2
- 238000005056 compaction Methods 0.000 description 2
- KUNSUQLRTQLHQQ-UHFFFAOYSA-N copper tin Chemical compound [Cu].[Sn] KUNSUQLRTQLHQQ-UHFFFAOYSA-N 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
- 229920003023 plastic Polymers 0.000 description 2
- -1 polyethylene Polymers 0.000 description 2
- 229920000573 polyethylene Polymers 0.000 description 2
- 239000011148 porous material Substances 0.000 description 2
- 230000000717 retained effect Effects 0.000 description 2
- 239000002002 slurry Substances 0.000 description 2
- 229920002449 FKM Polymers 0.000 description 1
- 239000004677 Nylon Substances 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- 238000005266 casting Methods 0.000 description 1
- 230000005465 channeling Effects 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000005315 distribution function Methods 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 229920001903 high density polyethylene Polymers 0.000 description 1
- 239000004700 high-density polyethylene Substances 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 230000013011 mating Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 229920001778 nylon Polymers 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 229920003002 synthetic resin Polymers 0.000 description 1
- 239000000057 synthetic resin Substances 0.000 description 1
- 239000011800 void material Substances 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/20—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the sorbent material
- B01D15/206—Packing or coating
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/22—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the construction of the column
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/50—Conditioning of the sorbent material or stationary liquid
- G01N30/52—Physical parameters
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/60—Construction of the column
- G01N30/6047—Construction of the column with supporting means; Holders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/60—Construction of the column
- G01N30/6091—Cartridges
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/50—Conditioning of the sorbent material or stationary liquid
- G01N30/52—Physical parameters
- G01N2030/522—Physical parameters pressure
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/60—Construction of the column
- G01N30/6004—Construction of the column end pieces
- G01N30/6017—Fluid distributors
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Sampling And Sample Adjustment (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/001,540 US4228007A (en) | 1979-01-08 | 1979-01-08 | Chromatographic cartridge and holder |
| US1540 | 1979-01-08 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS59112261A JPS59112261A (ja) | 1984-06-28 |
| JPH0346783B2 true JPH0346783B2 (US07534539-20090519-C00280.png) | 1991-07-17 |
Family
ID=21696577
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP82980A Pending JPS5598357A (en) | 1979-01-08 | 1980-01-08 | Method of chromatography and compressor for chromatographic cartridge |
| JP58192300A Pending JPS59112262A (ja) | 1979-01-08 | 1983-10-14 | クロマトグラフイ−・カラム |
| JP58192301A Granted JPS59112261A (ja) | 1979-01-08 | 1983-10-14 | クロマトグラフイ−・カラムの圧縮装置 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP82980A Pending JPS5598357A (en) | 1979-01-08 | 1980-01-08 | Method of chromatography and compressor for chromatographic cartridge |
| JP58192300A Pending JPS59112262A (ja) | 1979-01-08 | 1983-10-14 | クロマトグラフイ−・カラム |
Country Status (10)
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2930962A1 (de) * | 1979-07-31 | 1981-02-19 | Merck Patent Gmbh | Chromatographiesaeule |
| FR2522154A1 (fr) * | 1982-02-25 | 1983-08-26 | Instruments Sa | Dispositif de chromatographie et procede de mise en oeuvre |
| US4451363A (en) * | 1982-03-03 | 1984-05-29 | Brownlee Labs Inc. | Cartridge for liquid chromatograph |
| PL138838B1 (en) * | 1982-10-01 | 1986-11-29 | Politechnika Gdanska | Column for liquid chromatography |
| JPS61154562U (US07534539-20090519-C00280.png) * | 1985-03-15 | 1986-09-25 | ||
| US4894152A (en) * | 1987-08-13 | 1990-01-16 | Cerex Corporation | Fluid control device |
| US4856676A (en) * | 1987-09-03 | 1989-08-15 | Jet Spray Corp. | Post mix dispenser |
| SE8800644L (sv) * | 1988-02-25 | 1989-08-26 | Pharmacia Ab | Anordning foer att moejliggoera olika gelbaeddshoejder i en kromatografisk separationskolonn |
| SE501195C2 (sv) * | 1993-04-26 | 1994-12-05 | Pharmacia Lkb Biotech | Sätt och anordning för vätskekromatografi |
| US5730943A (en) * | 1993-08-12 | 1998-03-24 | Optimize Technologies, Inc. | Integral fitting and filter of an analytical chemical instrument |
| EP0884081A3 (en) * | 1993-08-12 | 1999-02-17 | Optimize technologies, Inc. | Integral fitting and filter |
| US6132605A (en) * | 1997-11-12 | 2000-10-17 | Dyax Corporation | Apparatus and method for making a sealable connection to a chromatography cartridge |
| EP1044047A4 (en) * | 1997-11-14 | 2008-04-16 | Biotage Inc | LIQUID CHROMATOGRAPHY COLUMN |
| JP2001524670A (ja) * | 1997-11-20 | 2001-12-04 | イーエスエー・インコーポレーテッド | 電気化学的分析システム |
| US6348150B1 (en) | 1998-05-15 | 2002-02-19 | Waters Investments Limited | Permanently radially compressed column |
| US6096204A (en) * | 1999-03-04 | 2000-08-01 | Waters Investments Limited | Permanently radially compressed column |
| US20090056541A1 (en) * | 2001-08-01 | 2009-03-05 | Davison Dale A | Method and apparatus for high resolution flash chromatography |
| US8696902B2 (en) * | 2007-01-09 | 2014-04-15 | Optimize Technologies, Inc. | High pressure connect fitting |
| EP2166349A1 (en) * | 2008-09-22 | 2010-03-24 | Bia Separations D.O.O. | Sample distribution device of samples in liquid chromatographs |
| US20110290731A1 (en) * | 2010-06-01 | 2011-12-01 | Ozbal Can C | Cartridge changers and methods for utilizing the same |
| DE102012222828A1 (de) * | 2012-12-11 | 2014-06-12 | Agilent Technologies, Inc. - A Delaware Corporation - | Vorbefüllte Flüssigkeitskartusche zur Versorgung eines Probentrenngeräts mit einer Betriebsflüssigkeit |
| JP6874005B2 (ja) * | 2015-09-22 | 2021-05-19 | ワイアット テクノロジー コーポレイションＷｙａｔｔ Ｔｅｃｈｎｏｌｏｇｙ Ｃｏｒｐｏｒａｔｉｏｎ | 液体サンプルからの複数の信号を測定する方法および装置 |
| JP7081059B2 (ja) * | 2020-03-27 | 2022-06-06 | 積水メディカル株式会社 | 液体クロマトグラフィー用部材 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5276091A (en) * | 1975-12-08 | 1977-06-25 | Waters Associates Inc | Radial compression of filling bed |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB837363A (en) * | 1957-03-21 | 1960-06-15 | Lkb Produkter Fabriksaktiebola | Apparatus for the separation of substances dissolved in a liquid |
| DE1773578U (de) | 1958-01-02 | 1958-09-04 | Franz K Heisig | Sortieranlage fuer automaten. |
| US3005514A (en) * | 1959-04-20 | 1961-10-24 | Cons Electrodynamics Corp | Fluid treating columns |
| US3307333A (en) * | 1963-10-31 | 1967-03-07 | Perkin Elmer Corp | Chromatographic columns |
| US3387630A (en) * | 1965-04-22 | 1968-06-11 | Dow Chemical Co | Adjustable pressure reducing device |
| US3298527A (en) * | 1965-05-17 | 1967-01-17 | Wright John Lemon | Chromatographic flow column |
| US3440864A (en) * | 1966-10-03 | 1969-04-29 | Phoenix Precision Instr Co | Liquid chromatographic column |
| GB1236094A (en) * | 1967-06-07 | 1971-06-16 | Abcor Inc | Apparatus for the chromatographic separation of fluids |
| US3453811A (en) * | 1968-05-03 | 1969-07-08 | Abcor Inc | Chromatographic columns with partition elements therein |
| US3687287A (en) * | 1970-02-11 | 1972-08-29 | English Clays Lovering Pochin | Tube pressure filters |
| NL7215099A (US07534539-20090519-C00280.png) * | 1971-12-07 | 1973-06-12 | ||
| FR2219797B1 (US07534539-20090519-C00280.png) * | 1973-03-01 | 1978-03-03 | Roussel Uclaf | |
| US4093550A (en) * | 1975-06-04 | 1978-06-06 | Riedel-De Haen Aktiengesellschaft | Column for high pressure liquid chromatography |
| US4070285A (en) * | 1975-12-24 | 1978-01-24 | Waters Associates, Inc. | Chromatography tube |
| US4059523A (en) * | 1976-09-23 | 1977-11-22 | Japan Spectroscopic Co., Ltd. | Column for use in high speed liquid chromatography |
| FR2413110A1 (fr) * | 1977-12-30 | 1979-07-27 | Anvar | Dispositif de chromatographie |
| DE2900344C2 (de) * | 1978-01-06 | 1986-09-25 | Waters Associates, Inc., Milford, Mass. | Chromatographiesäule |
-
1979
- 1979-01-08 US US06/001,540 patent/US4228007A/en not_active Expired - Lifetime
- 1979-11-06 CA CA000339289A patent/CA1141561A/en not_active Expired
- 1979-11-21 AU AU53064/79A patent/AU521324B2/en not_active Ceased
- 1979-12-21 NL NLAANVRAGE7909245,A patent/NL179977C/xx not_active IP Right Cessation
- 1979-12-28 GB GB7944432A patent/GB2038659B/en not_active Expired
-
1980
- 1980-01-03 CH CH16/80A patent/CH647333A5/de not_active IP Right Cessation
- 1980-01-08 DE DE3050819A patent/DE3050819C2/de not_active Expired
- 1980-01-08 JP JP82980A patent/JPS5598357A/ja active Pending
- 1980-01-08 BE BE0/198887A patent/BE881045A/fr not_active IP Right Cessation
- 1980-01-08 FR FR8000315A patent/FR2445965A1/fr active Granted
- 1980-01-08 DE DE3000475A patent/DE3000475C2/de not_active Expired
-
1983
- 1983-10-14 JP JP58192300A patent/JPS59112262A/ja active Pending
- 1983-10-14 JP JP58192301A patent/JPS59112261A/ja active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5276091A (en) * | 1975-12-08 | 1977-06-25 | Waters Associates Inc | Radial compression of filling bed |
Also Published As
| Publication number | Publication date |
|---|---|
| BE881045A (fr) | 1980-05-02 |
| DE3050819C2 (US07534539-20090519-C00280.png) | 1987-01-15 |
| DE3000475C2 (de) | 1985-10-03 |
| NL179977B (nl) | 1986-07-16 |
| FR2445965A1 (fr) | 1980-08-01 |
| NL7909245A (nl) | 1980-07-10 |
| GB2038659A (en) | 1980-07-30 |
| AU521324B2 (en) | 1982-03-25 |
| NL179977C (nl) | 1986-12-16 |
| JPS5598357A (en) | 1980-07-26 |
| US4228007A (en) | 1980-10-14 |
| GB2038659B (en) | 1983-05-11 |
| CH647333A5 (de) | 1985-01-15 |
| CA1141561A (en) | 1983-02-22 |
| DE3000475A1 (de) | 1980-07-31 |
| JPS59112262A (ja) | 1984-06-28 |
| FR2445965B1 (US07534539-20090519-C00280.png) | 1984-10-05 |
| JPS59112261A (ja) | 1984-06-28 |
| AU5306479A (en) | 1980-07-17 |
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