JPH0324626B2 - - Google Patents
Info
- Publication number
- JPH0324626B2 JPH0324626B2 JP58033000A JP3300083A JPH0324626B2 JP H0324626 B2 JPH0324626 B2 JP H0324626B2 JP 58033000 A JP58033000 A JP 58033000A JP 3300083 A JP3300083 A JP 3300083A JP H0324626 B2 JPH0324626 B2 JP H0324626B2
- Authority
- JP
- Japan
- Prior art keywords
- jet
- amplitude
- classification
- waves
- particle analysis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002245 particle Substances 0.000 claims description 56
- 238000001514 detection method Methods 0.000 claims description 28
- 238000004458 analytical method Methods 0.000 claims description 26
- 230000008859 change Effects 0.000 claims description 25
- 238000000034 method Methods 0.000 claims description 19
- 239000007788 liquid Substances 0.000 claims description 12
- 230000004044 response Effects 0.000 claims description 2
- 230000001678 irradiating effect Effects 0.000 claims 2
- 210000004027 cell Anatomy 0.000 description 12
- 239000013078 crystal Substances 0.000 description 10
- 238000010586 diagram Methods 0.000 description 10
- WABPQHHGFIMREM-UHFFFAOYSA-N lead(0) Chemical compound [Pb] WABPQHHGFIMREM-UHFFFAOYSA-N 0.000 description 8
- 239000011859 microparticle Substances 0.000 description 7
- 230000000694 effects Effects 0.000 description 6
- 239000012530 fluid Substances 0.000 description 6
- 230000007246 mechanism Effects 0.000 description 6
- 238000002347 injection Methods 0.000 description 5
- 239000007924 injection Substances 0.000 description 5
- 238000007689 inspection Methods 0.000 description 5
- 230000008878 coupling Effects 0.000 description 4
- 238000010168 coupling process Methods 0.000 description 4
- 238000005859 coupling reaction Methods 0.000 description 4
- 230000003287 optical effect Effects 0.000 description 4
- 210000000601 blood cell Anatomy 0.000 description 3
- 238000000926 separation method Methods 0.000 description 3
- 238000011144 upstream manufacturing Methods 0.000 description 3
- 230000000007 visual effect Effects 0.000 description 3
- 238000013459 approach Methods 0.000 description 2
- 238000000149 argon plasma sintering Methods 0.000 description 2
- 239000003990 capacitor Substances 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 238000012937 correction Methods 0.000 description 2
- 238000000684 flow cytometry Methods 0.000 description 2
- 238000012544 monitoring process Methods 0.000 description 2
- 230000005855 radiation Effects 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 230000003321 amplification Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000004163 cytometry Methods 0.000 description 1
- 230000001934 delay Effects 0.000 description 1
- 230000005684 electric field Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000002356 laser light scattering Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012806 monitoring device Methods 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 239000012266 salt solution Substances 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 230000001131 transforming effect Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1404—Handling flow, e.g. hydrodynamic focusing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/149—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1404—Handling flow, e.g. hydrodynamic focusing
- G01N2015/1406—Control of droplet point
Landscapes
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19833307789 DE3307789A1 (de) | 1983-03-04 | 1983-03-04 | Verfahren und vorrichtung zur anzeige einer aenderung des zerfallpunktes in einem tropfenerzeugungssystem |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS59159046A JPS59159046A (ja) | 1984-09-08 |
| JPH0324626B2 true JPH0324626B2 (enExample) | 1991-04-03 |
Family
ID=6192580
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP58033000A Granted JPS59159046A (ja) | 1983-03-04 | 1983-03-02 | 粒子分析分類装置 |
Country Status (8)
| Country | Link |
|---|---|
| JP (1) | JPS59159046A (enExample) |
| AU (1) | AU563027B2 (enExample) |
| CA (1) | CA1206559A (enExample) |
| CH (1) | CH654925A5 (enExample) |
| DE (1) | DE3307789A1 (enExample) |
| FR (1) | FR2542110B1 (enExample) |
| GB (1) | GB2136561B (enExample) |
| NL (1) | NL8300783A (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3512090C1 (de) * | 1985-04-03 | 1986-10-02 | Eltro GmbH, Gesellschaft für Strahlungstechnik, 6900 Heidelberg | Schaltungsanordnung zur Aufbereitung von gleichzeitig zur Verarbeitung anstehenden sehr unterschiedlich grossen Signalamplituden |
| JP4323571B2 (ja) | 1997-01-31 | 2009-09-02 | エックスワイ， インコーポレイテッド | 光学装置 |
| US6149867A (en) | 1997-12-31 | 2000-11-21 | Xy, Inc. | Sheath fluids and collection systems for sex-specific cytometer sorting of sperm |
| US6071689A (en) | 1997-12-31 | 2000-06-06 | Xy, Inc. | System for improving yield of sexed embryos in mammals |
| US7208265B1 (en) | 1999-11-24 | 2007-04-24 | Xy, Inc. | Method of cryopreserving selected sperm cells |
| AU760689B2 (en) * | 2000-03-28 | 2003-05-22 | Matsushita Electric Works Ltd. | Particle sensor |
| AU2002237689B2 (en) | 2000-11-29 | 2008-01-10 | Xy, Llc. | System to separate frozen-thawed spermatozoa into X-chromosome bearing and Y-chromosome bearing populations |
| US7713687B2 (en) | 2000-11-29 | 2010-05-11 | Xy, Inc. | System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations |
| GB2388585A (en) * | 2002-05-17 | 2003-11-19 | Unilever Plc | Dosing system with multi-spout nozzle |
| MX337304B (es) | 2002-08-01 | 2016-02-24 | Xy Llc | Sistema de separacion de baja presion para celulas de esperma. |
| US8486618B2 (en) | 2002-08-01 | 2013-07-16 | Xy, Llc | Heterogeneous inseminate system |
| WO2004017041A2 (en) | 2002-08-15 | 2004-02-26 | Xy, Inc. | High resolution flow cytometer |
| US7169548B2 (en) | 2002-09-13 | 2007-01-30 | Xy, Inc. | Sperm cell processing and preservation systems |
| DE602004024874D1 (de) | 2003-03-28 | 2010-02-11 | Inguran Llc | Eschlechts-sortierten tierspermien |
| EP1625203B1 (en) | 2003-05-15 | 2015-04-08 | Xy, Llc | Efficient haploid cell sorting for flow cytometer systems |
| EP1729789A2 (en) | 2004-03-29 | 2006-12-13 | Monsanto Technology, LLC | Sperm suspensions for use in insemination |
| JP2008507287A (ja) | 2004-07-22 | 2008-03-13 | モンサント テクノロジー エルエルシー | 精子細胞の集団を富化する方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3380584A (en) * | 1965-06-04 | 1968-04-30 | Atomic Energy Commission Usa | Particle separator |
| BE793185A (fr) * | 1971-12-23 | 1973-04-16 | Atomic Energy Commission | Appareil pour analyser et trier rapidement des particules telles que des cellules biologiques |
| US3963606A (en) * | 1974-06-03 | 1976-06-15 | Coulter Electronics, Inc. | Semi-automatic adjusting delay for an electronic particle separator |
| NL180704C (nl) * | 1976-06-14 | Coulter Electronics | Inrichting voor gelijktijdige optische meting van kenmerken van zich in een suspensie bevindende deeltjes. | |
| US4047183A (en) * | 1976-11-04 | 1977-09-06 | International Business Machines Corporation | Method and apparatus for controlling the formation and shape of droplets in an ink jet stream |
| US4318480A (en) * | 1979-08-20 | 1982-03-09 | Ortho Diagnostics, Inc. | Method and apparatus for positioning the point of droplet formation in the jetting fluid of an electrostatic sorting device |
-
1983
- 1983-02-07 CA CA000421053A patent/CA1206559A/en not_active Expired
- 1983-02-08 AU AU11244/83A patent/AU563027B2/en not_active Ceased
- 1983-02-08 GB GB08303440A patent/GB2136561B/en not_active Expired
- 1983-03-02 JP JP58033000A patent/JPS59159046A/ja active Granted
- 1983-03-03 NL NL8300783A patent/NL8300783A/nl not_active Application Discontinuation
- 1983-03-03 CH CH1159/83A patent/CH654925A5/fr not_active IP Right Cessation
- 1983-03-03 FR FR8303501A patent/FR2542110B1/fr not_active Expired
- 1983-03-04 DE DE19833307789 patent/DE3307789A1/de active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| AU563027B2 (en) | 1987-06-25 |
| DE3307789A1 (de) | 1984-09-06 |
| GB2136561A (en) | 1984-09-19 |
| GB8303440D0 (en) | 1983-03-16 |
| FR2542110B1 (fr) | 1988-11-04 |
| GB2136561B (en) | 1986-06-25 |
| JPS59159046A (ja) | 1984-09-08 |
| NL8300783A (nl) | 1984-10-01 |
| AU1124483A (en) | 1984-08-16 |
| FR2542110A1 (fr) | 1984-09-07 |
| DE3307789C2 (enExample) | 1991-09-19 |
| CA1206559A (en) | 1986-06-24 |
| CH654925A5 (fr) | 1986-03-14 |
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