JPH0316926B2 - - Google Patents

Info

Publication number
JPH0316926B2
JPH0316926B2 JP58232723A JP23272383A JPH0316926B2 JP H0316926 B2 JPH0316926 B2 JP H0316926B2 JP 58232723 A JP58232723 A JP 58232723A JP 23272383 A JP23272383 A JP 23272383A JP H0316926 B2 JPH0316926 B2 JP H0316926B2
Authority
JP
Japan
Prior art keywords
reductase
ene
olean
acid
testosterone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP58232723A
Other languages
English (en)
Japanese (ja)
Other versions
JPS60126218A (ja
Inventor
Masatsune Kurono
Takashi Iida
Hideshi Yamakawa
Tatsuhiko Suzuki
Takuya Koshizaka
Hidekazu Kato
Kunio Yagi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
VITAMIN KENKYUSHO KK
Original Assignee
VITAMIN KENKYUSHO KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by VITAMIN KENKYUSHO KK filed Critical VITAMIN KENKYUSHO KK
Priority to JP23272383A priority Critical patent/JPS60126218A/ja
Publication of JPS60126218A publication Critical patent/JPS60126218A/ja
Publication of JPH0316926B2 publication Critical patent/JPH0316926B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP23272383A 1983-12-12 1983-12-12 トリテルペン化合物又はその塩を有効成分とするテストステロン−5α−リダクタ−ゼ阻害剤 Granted JPS60126218A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP23272383A JPS60126218A (ja) 1983-12-12 1983-12-12 トリテルペン化合物又はその塩を有効成分とするテストステロン−5α−リダクタ−ゼ阻害剤

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP23272383A JPS60126218A (ja) 1983-12-12 1983-12-12 トリテルペン化合物又はその塩を有効成分とするテストステロン−5α−リダクタ−ゼ阻害剤

Publications (2)

Publication Number Publication Date
JPS60126218A JPS60126218A (ja) 1985-07-05
JPH0316926B2 true JPH0316926B2 (enrdf_load_stackoverflow) 1991-03-06

Family

ID=16943772

Family Applications (1)

Application Number Title Priority Date Filing Date
JP23272383A Granted JPS60126218A (ja) 1983-12-12 1983-12-12 トリテルペン化合物又はその塩を有効成分とするテストステロン−5α−リダクタ−ゼ阻害剤

Country Status (1)

Country Link
JP (1) JPS60126218A (enrdf_load_stackoverflow)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5571817A (en) * 1984-02-27 1996-11-05 Merck & Co., Inc. Methods of treating androgenic alopecia with finasteride [17β-N-mono-substituted-carbamoyl-4-aza-5-α-androst-1-en-ones]
JPS61197516A (ja) * 1985-02-27 1986-09-01 Tsumura Juntendo Inc 抗高テストステロン血症剤
JPS6236330A (ja) * 1985-08-12 1987-02-17 Oyo Seikagaku Kenkyusho:Kk センブリ抽出エキス及びその製法
CA1308661C (en) * 1987-06-26 1992-10-13 Masayasu Kurono AGENT FOR INHIBITING BINDING OF 5.alpha.-DIHYDRO-TESTOSTERONE WITH ANDROGEN RECEPTOR AS WELL AS PROCESS FOR OBTAINING SAME
FR2709952B1 (fr) * 1993-09-15 1997-06-27 Betourne Michel Utilisation d'un sel d'amMonium de l'acide 18 B glycirrhitique pour son action biostimulante sur la pousse du cheveu.
JP2002520375A (ja) * 1998-07-17 2002-07-09 ザ・ユニバーシティ・オブ・テキサス・サウスウエスタン・メディカル・センター 育毛調節のためのトリテルペンを含む成分
US6482857B1 (en) 1998-07-17 2002-11-19 The University Of Texas Southwestern Medical Center Compositions which contain triterpenes for regulating hair growth
US6124362A (en) 1998-07-17 2000-09-26 The Procter & Gamble Company Method for regulating hair growth
KR100368297B1 (ko) * 2000-05-31 2003-01-24 이승기 양성 전립선 비대증 치료용 메나퀴논 7
JP4803698B2 (ja) * 2004-11-02 2011-10-26 丸善製薬株式会社 抗老化剤、エストロゲン様作用剤、抗男性ホルモン剤、育毛剤、テストステロン5α−レダクターゼ阻害剤、皮膚化粧料及び頭髪化粧料
CN101193907B (zh) * 2005-06-10 2012-07-11 宝丽化学工业有限公司 三萜酸衍生物和包含其的皮肤外用剂
US20230023847A1 (en) * 2020-02-05 2023-01-26 Lg Household & Health Care Ltd. Composition for preventing hair loss and promoting hair regrowth

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56139416A (en) * 1980-04-01 1981-10-30 Minofuaagen Seiyaku Honpo:Goushi Antiulcer, anti-inflammatory and antiallergic agent, containing olean-12-ene-3beta, 3o-diol as main constituent, and having no side effect of glycylrrhetinic acid

Also Published As

Publication number Publication date
JPS60126218A (ja) 1985-07-05

Similar Documents

Publication Publication Date Title
Liang et al. Inhibition of 5 alpha-reductase, receptor binding, and nuclear uptake of androgens in the prostate by a 4-methyl-4-aza-steroid.
Ruokonen et al. Free and sulfate-conjugated neutral steroids in human testis tissue
Voigt et al. Further studies on testosterone 5α-reductase of human skin: Structural features of steroid inhibitors
JPH0316926B2 (enrdf_load_stackoverflow)
JPH10503197A (ja) 汗関連症状の治療法
JP2003519624A (ja) 置換サポゲニン及びそれらの使用
Pashko et al. Inhibition of DNA synthesis in mouse epidermis and breast epithelium by dehydroepiandrosterone and related steroids
Pérez-Ornelas et al. New 5α-reductase inhibitors: in vitro and in vivo effects
BUTLER et al. The metabolism of betamethasone
Morris et al. Chromatographic separation of aldosterone and its metabolites
JP2655646B2 (ja) アンドロゲン受容体結合阻害剤
Takashima et al. Studies of Common Baldness in the Stumptailed Macaque IV. In Vitro Metabolism of Testosterone in the Hair Follicles
JPH013126A (ja) アンドロゲン受容体結合阻害剤
CALVIN et al. Studies on the metabolism of pregnenolone sulfate
Murota et al. Androgen formation in the testicular tissue of patients with prostatic carcinoma
Nozu et al. Testosterone metabolism in subcellular fractions of rat prostate
DE102004032674A1 (de) Neue 2-substituierte Estra-1,3,5(10)-trien-17-one als Inhibitoren der 17β-Hydroxysteroiddehydrogenase Typ 1
Lønning et al. Pharmacokinetics and metabolism of formestane in breast cancer patients
Bu'Lock et al. Suppression of testicular androgen synthesis in the rat by ethane 1, 2, dimethanesulphonate
LEINONEN et al. Effects of estrogen treatment on human testicular unconjugated steroid and steroid sulfate production in vivo
Cabeza et al. Androgenic and anti-androgenic effects of progesterone derivatives with different halogens as substituents at the C-6 position
JP3325026B2 (ja) 4−アザ−プレグナン5α−レダクターゼアイソザイム1阻害剤
Zmigrod et al. Reductive pathways of progesterone metabolism in the rat ovary
US5561124A (en) 17-α-acyl steroids which inhibit 5-α-reductase
Migeon Adrenocortical function and plasma 17-ketosteroids in man