JPH0234902Y2 - - Google Patents

Description

[Detailed Description of the Invention] (Field of Industrial Application) The present invention relates to a device for dispensing a medical radioactive drug solution from a container to a syringe, and in particular, the invention relates to a device for dispensing a medical radioactive drug solution from a container to a syringe. This relates to a matching device.

(Prior Art) In recent years, radioisotope RI is administered into a patient's body and used as a tracer for diagnosis. Radiological diagnosis is actively performed. In this case, since radioactivity is emitted from the chemical solution itself, there is an extremely high risk that the operator will be exposed to radiation during handling.

FIG. 5 shows a conventional method for dispensing this type of chemical solution. In Figure 5, 1 is a container (vial bottle) containing a radioactive drug solution (hereinafter referred to as RI), 2 is a shield made of lead etc. (vial shield) to prevent radioactivity from escaping, and 3
4 is a syringe for dispensing the required amount of RI, 4 is a shield made of lead etc. that is placed over the cylinder part of syringe 3 to prevent radioactivity from escaping, 5
is a lead glass that allows the scale of the syringe inside to be seen.

The operator holds the syringe 3 equipped with the shield 4 in his hand, sticks the needle into the stopper of the container 1, and inserts the piston 3.
After pulling a and dispensing the required amount of RI, the needle is removed and the patient is directly injected.

(Problems that the invention aims to solve) However, in the conventional dispensing method described above, although shields 2 and 4 are installed, they are not perfect, so there is radioactivity leakage, and furthermore, it is manual operation. However, it was unavoidable that the operator would be exposed to radiation during the dispensing process.

This invention is a radiopharmaceutical liquid dispensing device that automatically performs dispensing operations to minimize radioactivity exposure to the operator. An object of the present invention is to provide a positioning device that moves a moving plate supporting a container holding plate so that the needle position of a syringe held with the needle facing upward matches the position of the needle.

(Means for Solving the Problems) In order to achieve the above object, the drug solution container and syringe needle positioning device of the present invention adjusts the height position of the tip of the needle and the needle position in the X-Y directions, respectively. A needle position detection sensor unit that detects, a movement mechanism that moves a moving plate that supports a container holding plate in the X-Y direction, and a needle position detection unit that detects when the needle tip reaches a predetermined height during dispensing. A detection signal from the sensor unit causes the syringe holding unit to temporarily stop rising, and then a movement mechanism is activated so that the position of the stopper of the container matches the position of the needle of the syringe based on the detection signal that detects the needle position in the X-Y direction. It is composed of a control section that controls the control section.

In addition, the moving mechanism has a plurality of rollers arranged on the top plate of the device housing, a rotatable wheel at the tip, a plurality of arms each rotated by a motor, and a container holding plate. , a movable plate that rests on the rollers and has a plurality of elongated holes in which the wheels of the arm movably engage, respectively.

(Function) When dispensing, first, the needle tip of the syringe is raised to the position of the needle position detection sensor section, and then stopped there. Further, the needle position detection sensor unit detects the needle position in the X-Y direction, and based on the signal, the position of the stopper of the container is moved to match the position of the needle of the syringe. In the matched state, raise the syringe a certain distance and stick the needle into the stopper of the container to dispense the desired amount of RI.

(Example) Hereinafter, an example will be described in detail with reference to the drawings. First, FIG. 6 shows the appearance of a radiopharmaceutical liquid dispensing device equipped with an alignment device, which is one embodiment of the present invention. 51 is the main body of the dispensing device, 52 is the controller, and 53 is a cable connecting the two, including a power line and a signal line. 54 is a power cord. A container containing RI and a syringe for dispensing a desired amount of RI from the container are set in the dispensing device main body 51. The controller 52 includes
It has an input section for setting the desired dispensing amount, a display section, a start button, etc., and a built-in CPU that controls all operations of the dispensing device.

1 to 4 show the internal structure of the dispensing device main body 51. As shown in FIG. First, in FIG. 1 showing the front and top surfaces of the device, 11 is a housing, 12 is a housing, and 12 is a housing.
14 is a syringe holder that holds a syringe 16 with a needle 15 facing upward; 17 is a container holder that covers the cylinder of the syringe 16; A shield made of lead, 18 a lead glass provided so that the scale of the syringe can be seen, and 19 a piston end holder that holds the end of the piston 20 of the syringe. Shield 1 attached to the syringe
7 has a steel plate on the back, and the syringe holding part 1
No. 4 has a magnet embedded in the facing part, so the syringe can be easily attached and detached. 30 is a pulse motor.

Next, in FIG. 2 showing the back of the device and the internal structure of the container holding part 12, 21 is a rack fixed to the housing 11, and has a groove in the center as described later. 22 is a grooved rail fixed to the housing, 23 is a grooved rack fixed to the panel of the syringe holding part 14, and 24 is a grooved rail fixed to the panel of the syringe holding part 14. . Reference numerals 25a to 25d are rotatable wheels provided on the panel of the syringe holder 14, and are engaged with the grooves of the rack 21 or the grooves of the rail 22. 26a
-26d is a rotatable wheel provided on the panel of the piston end holding portion 19, and is engaged with a groove of the rack 23 or a groove of the rail 24. 27 and 28 are pulse motors, and 29 is a limit switch.

The rack 21, the rail 22, the wheels 25a to 25d, and the pulse motor 27 constitute an elevating mechanism (first elevating mechanism) for the syringe holder 14.
The main part is shown enlarged in FIG. That is, the four rotatable wheels 25a to 25d provided on the panel of the syringe holder 14 are connected to the groove 31a of the rack 21.
is engaged with the groove 31b of the rail 22, and on the other hand,
A pinion 32 connected to a pulse motor 27 fixed to a panel of the syringe holding part 14 via a built-in speed reducer meshes with the teeth of the rack 21, so that the rotation of the pulse motor 27 causes the syringe holding part to rotate. 14 goes up and down. Similarly, Rack 23,
The rail 24, the wheels 26a to 26d, and the pulse motor 28 constitute an elevating mechanism (second elevating mechanism) for the piston end holder 19 relative to the syringe holder 14. The elevating mechanism having the above structure is characterized in that it moves smoothly and generates very little noise compared to a mechanism that uses a worm gear or the like.

Further, in FIG. 2, 35 is a container holding plate;
6 is a moving plate, 37 is a needle position detection sensor section, 38,
39 is a pulse motor fixed to the top plate 40 of the casing for moving the moving plate 36.

The needle 15 attached to the syringe does not always align with the axis of the syringe. Furthermore, a syringe attached by a chuck means using a magnet may be slightly misaligned. Therefore, if the needle tip is attached with the needle tip deviated from the axis, the syringe will be deviated from the mouth of the container 13 even if the syringe is raised as it is. Therefore, it is necessary to first detect the position of the needle tip and then move the container to match it. As the configuration of the needle position detection sensor section 37, for example, it is possible to use one in which a plurality of pairs of optical sensors (with a light emitting element and a light receiving element facing each other) are arranged side by side on two sets of mutually opposing sides of a square frame. .

FIG. 4 shows a mechanism for moving the moving plate 36. The housing top plate 40 has arms 41a, 41
b and 41c are rotatably provided, and their rotation axes are driven by pulse motors 38 and 39, respectively, shown in FIG.
and is connected to a pulse motor 30 shown in FIG. The arms 41a, 41b, 41c are provided with rotatable wheels 42a, 42b, 42c, respectively, and these wheels connect the long holes 4 formed in the moving plate 36.
3a, 43b, and 43c (see Fig. 1).
The moving plate 36 includes rollers 44a arranged on the top plate 40,
44b, 44c, is biased in the direction of arrow P by a spring or the like (not shown), and initial positions are set by limit switches 45a, 45b, 45c. When aligning the tip of the injection needle 15 with the opening of the container, the pulse motor 30 is driven to rotate the arm 41c to move the moving plate 36 by the necessary amount in the X direction, and then the pulse motors 38 and 39 are driven. The arms 41a and 41b are rotated to move the moving plate 36 by the necessary amount in the Y direction.

FIG. 7 shows the positioning control system, in which the needle position detection sensor section 37 includes a needle position detector in the vertical direction provided at the A level position and an X, Y needle position detector provided at the B level position. These detection signals are sent to the control section 55 of the controller 52. The control section 55 controls the pulse motors 27 and 28 based on the detection signal to drive the syringe holding section 14 and the piston end holding section 19. In addition, pulse motors 30, 38 and 39
is controlled to rotate the arms 41a, 41b, and 41c to align the position of the mouth of the container with the position of the needle.

Next, the operation of this embodiment will be explained with reference to the flowchart shown in FIG. First, as an initial setting, the container 13 containing RI is placed upside down on the holding plate 35, and the syringe 16 is placed on the syringe holding part 14.
Set to . Also, the dispensing capacity (e.g. 2.0ml)
is input at the input section of the controller 52. When the start button is pressed, the pulse motor 27 rotates and the first
The syringe holding part 14 is raised by the raising and lowering mechanism. When the needle tip reaches the upper chain line A shown in the needle position detection sensor section 37 in FIG. 2, the syringe holding section 14 temporarily stops. Therefore, the needle position in the X direction is first detected by the sensor disposed at the level of the lower chain line B shown in the needle position detection sensor section 37, and the pulse motor 30 operates according to the needle position, and the moving plate 36
The position is adjusted. Similarly, the needle position in the Y direction is detected, the pulse motors 38 and 39 are operated, and the position of the moving plate 36 is adjusted. After the needle position matches the position of the stopper of the container, the pulse motor 27 rotates again, the syringe holder 14 is raised a predetermined distance by the first elevating mechanism, and the needle is inserted into the stopper of the container. The needle tip reaches the RI in the container 13.

Next, the pulse motor 28 rotates, and the second elevating mechanism operates to lower the piston end holder 19, which holds the end of the piston of the syringe, by a distance corresponding to a preset dispensing volume to the desired level. Dispense the amount of RI into a syringe. In that state, pulse motor 2
7 rotates, the first elevating mechanism operates, the syringe holder 14 descends, and the needle is removed from the stopper of the container.
When the syringe holding part 14 returns to the initial position, the syringe is removed. Furthermore, the pulse motor 28 rotates, and the piston end holding part 19 returns to the initial position.
Dispensing work is completed.

The above operations are executed under the control of a pre-programmed controller.

(Effects of the invention) As explained above, according to the invention, the positioning of the drug solution container and the syringe needle is automatically performed,
Since the raised syringe needle can pass through the stopper of the container and reliably dispense the desired amount of RI, the chances of radiation exposure to the operator are greatly reduced, increasing safety. In addition, the moving mechanism that aligns the opening of the container containing the drug solution with the needle position of the set syringe places a moving plate carrying a container holding plate on a roller provided on the top plate of the housing, and rotates the arm. Since the movable plate is moved in the X-Y direction, the structure is extremely simple and the position can be adjusted with high precision.

[Brief explanation of the drawing]

FIG. 1 is a perspective view showing the front and top surfaces of the dispensing device main body according to an embodiment of the present invention, FIG. 2 is a view showing the back surface and the internal structure of the container holder, and FIG. FIG. 4 is a perspective view showing the mechanism, FIG. 4 is a view showing the X-Y moving mechanism of the container holder, FIG. 5 is a view showing the conventional dispensing method, and FIG. 6 is an example of the present invention. FIG. 7 is a block diagram of the alignment control system, and FIG. 8 is a flowchart of the dispensing operation. 12... Container holding part, 13... Container, 14...
Syringe holding part, 15... Needle, 16... Syringe, 1
9... Piston end holding part, 27, 28, 30, 3
8, 39... Pulse motor, 35... Container holding plate, 36... Moving plate, 37... Needle position detection sensor section, 40... Top plate, 41a to 41c... Arm,
42a-42c...wheels, 43a-43c...elongated holes, 44a-44c...rollers, 51...dispensing device main body, 52...controller.

Claims (1)

[Claims for Utility Model Registration] A container holding plate 35 that holds a container 13 containing a radiochemical solution in an inverted state, a moving plate 36 that supports the container holding plate and is movable in the X-Y direction, and the container. Syringe 16 with needle 15 pointing upwards below 13
a syringe holder 14 that can be moved up and down while holding the syringe holder; In a radiopharmaceutical liquid dispensing device comprising a piston end holder 19 that holds and pulls the syringe holder 14 and a control unit that controls vertical movement of the syringe holder 14 and the piston end holder 19, the tip of the needle 15 is Needle position detection sensor unit 3 that detects the height position and the needle position in the X-Y direction
7, a moving mechanism for moving the moving plate 36 in the X-Y direction, and a mechanism for holding the syringe based on a detection signal from the needle position detection sensor unit that detects that the needle tip has reached a predetermined height during dispensing. control unit 55 that controls the moving mechanism so that the position of the stopper of the container 13 coincides with the position of the needle of the syringe based on a detection signal obtained by detecting the needle position in the X-Y direction; The moving mechanism includes a plurality of rollers 44a, 44b, 44c disposed on the top plate 40 of the device housing, and a motor 30, which has rotatable wheels 42a, 42b, 42c at the tip thereof. A plurality of arms 41a, 41b, 41c rotate by 38, 39, respectively, and support the container holding plate 35, and rest on the roller,
and a movable plate 36 having a plurality of elongated holes 43a, 43b, and 43c with which the wheels of the arm movably engage, respectively, and by rotating the arm, the movable plate is moved in the X and Y directions. A device for aligning a drug solution container and a syringe needle of a radiation drug solution dispensing device.