JPH0231856A - Discharger for pattern coating - Google Patents

Abstract

PURPOSE:To form one pattern of a coating soln. without moving a liq. discharge nozzle by providing plural penetrating holes to the nozzle, and discharging the coating soln. simultaneously from the holes. CONSTITUTION:Plural penetrating holes 4, 4,... are provided to the liq. discharge nozzle 3, the holes 4 necessary for forming a pattern are opened, and other holes are closed. An adapter 20 is fixed, for example, to the unused hole 4 to close an optional hole 4. The coating soln. is dripped simultaneously from the open holes, and a pattern of the coating soln. is drawn on a supporting body without moving the nozzle. The diameter and position of each penetration hole 4 are specified so that the thickness of the formed pattern is uniformized.

Description

[Detailed Description of the Invention] [Industrial Application Field] The present invention relates to a coating device for pattern coating, and more specifically, it is used to perform analysis (1) for manufacturing biochemical analysis elements etc. by color reaction with blood etc. The present invention relates to a discharging device for pattern-coating a coating liquid onto a support.

[Prior Art] As an analysis element for chemically analyzing the presence or absence of a specific component in a liquid sample such as blood or serum, or its presence, an adhesive layer, a reagent layer, and a spreader are coated on a support-F. Biochemical analysis elements formed by laminating layers are known. Conventionally, such a biochemical analysis element is provided by applying a spreading layer or the like to the entire surface of a translucent sheet (7) support using a blade coater, drying it, and then cutting it into a square with a side of about 14 m. was.

Biochemical analysis is performed by dropping blood, etc. onto such a biochemical analysis element and developing a color reaction, but the blood, etc. spreads out in a circular shape from the center and participates in the reaction only in one part of the biochemical analysis element. Use expensive spreading agents etc. all over your body! 1
Layering is wasteful in terms of manufacturing costs. Coating with a rough blade coater orients the RH contained in the spreading layer, making uniform spreading of blood, etc. impossible. Patent application filed by the applicant in 1983-80 to improve the above problems
No. 73, Japanese Patent Application No. 63-8075, etc., propose a technique of pattern-coating a developing layer or the like using a discharging device.

[Problems to be Solved by the Invention] The above-mentioned discharge device for pattern coating has a liquid reservoir provided directly above the flow control pump and supplies liquid from this liquid reservoir in order to accurately control the supply liquid conflict. However, the liquid discharge nozzle of the discharge device has only one through hole, and pattern application is performed by moving the liquid discharge nozzle so as to draw a pattern. The above-mentioned liquid discharge nozzle transfer J is usually performed by a robot,
There is a problem in that there is a certain limit to the speed due to limitations on the liquid ejection speed, and that it takes a long time to coat each pattern. The present invention has been made to solve the above-mentioned problems, and an object of the present invention is to provide a pattern coating discharging device that requires a short coating time per pattern.

[Means for solving the problem] A flow control pump is installed below the liquid reservoir and connected to the liquid reservoir, and a liquid discharge nozzle is arranged on the discharge side of the flow rate control pump for pattern coating to supply the coating liquid. In the discharging device, the liquid discharging nozzle is provided with a plurality of through holes, and a through hole is selected from the plurality of through holes using means for opening and closing the through holes to discharge the coating liquid.

[Function] The liquid discharge nozzle has a plurality of through holes, and the coating liquid is simultaneously discharged from the plurality of through holes, so if a support is placed where the coating liquid is dropped, One coating liquid pattern can be formed without moving the liquid discharge nozzle, and the time required for this is shortened.

[Example] Embodiments of the present invention will be described below with reference to the drawings.

In FIG. 1, a mono pump 2, which is a flow rate control pump, is connected below a liquid reservoir 1 for storing a coating liquid, and a liquid discharge nozzle 3 is provided on the discharge side of the mono pump 2.

As shown in FIG. 2, the Mono pump 2 includes a helical rotating body 2b with a circular cross section inside a stator 2a of an elastic body having a gap in which the direction of the long axis of an oval cross section changes in the height direction. The rotating body 2b is rotated by a pulse motor 5 placed above the liquid reservoir 1. Such a mono pump discharges the liquid in the liquid reservoir 1 of the cloth from the liquid discharge nozzle 3 in proportion to the rotational speed of the rotating body 2b, and also reverses the flow direction of the liquid by rotating the rotating body 2b in the opposite direction. By instantly sucking the liquid, dripping is prevented. A coating liquid is supplied to the liquid reservoir 1 by a coating liquid supply pump 6. The pattern coating discharge device 11 configured as described above is supported by the robot 7 and can be moved along any desired path. Robots 1-7 above
, the pulse motor 5 and the coating liquid supply pump 6 are connected to the control panel 8.
Its movement is controlled by The liquid discharge nozzle 3, which is a characteristic part of the present invention, has a plurality of through holes 4. . . . Among these through holes 4, necessary ones are selected according to the shape of the pattern to be formed, and unused through holes 4 are closed. As the opening/closing means, for example, an adapter 20 shown in FIG.
It is possible to use That is, by attaching this adapter 20 to an unused through hole 4 as shown in FIGS. 6 and 7, it becomes possible to arbitrarily select and open the through hole 4. The material of the adapter 20 is preferably one that is inert to the coating liquid, and is preferably a metal such as stainless steel or a resin such as Python or Teflon.

At the same time, the coating liquid is dropped from the open holes, and a pattern of the coating liquid is drawn on the support without moving the liquid discharge nozzle. The diameter and position of each of the plurality of through holes 4, 4°, etc. are determined so that the thickness of the formed coating liquid pattern is uniform.

Next, a case will be described in which a biochemical analysis element is manufactured using the above-mentioned pattern coating 1 oh mounting method.

As a support, the thickness is 180μ, the width is 500mm, and the length is 100mm.
0 m polyethylene terephthalate seam 1~ is used. The adhesive layer and the reagent layer are coated over the entire area of the support using a coating chamber such as a blade coater, and after these layers have dried, a moving stage that can move the support 9 in the vertical direction is applied as shown in FIG. Put it on 10. A robot 7 that supports the pattern coating discharge device 11 (as shown in the figure, is capable of scanning in the horizontal direction) positions the liquid discharge nozzle 3 at the first point P1 and adjusts the gap between the support 9 and the liquid discharge nozzle 3. After determining G, the rotating body 2b is circulated by the control panel 8, and the coating liquid is discharged from the liquid discharge nozzle 3 for the period necessary to form the spread layer.In this way, the pattern coating at the first point P1 is performed. After that, the pattern coating discharge device 11 is moved laterally by 14 meters by the robot 7, and the nozzle is moved to the second point P2.The reason why this movement interval is set to 14 mm is because the dimensions of the biochemical analysis element are 14 mm.
This is because it is set to 4m x 14an, but it may be set to other dimensions. After the first row is pattern-coated horizontally on the support 9 in this way, the movable table 10 is moved vertically by 14 ends, and the pattern-coating discharge device is operated in the same manner as described above to apply the pattern to the second row. is sequentially pattern-coated from the first point, and the coating of all the rows is completed, such as the third row and the fourth row, to form developed layers 12, 12, . . . as shown in FIG. 5.

After the developing layer dries, the support is slit with the developing layer in the center as shown by the broken line in FIG. 10, thereby forming a desired biochemical analysis element.
9.

[Effects of the Invention] As explained above, in the pattern coating discharge device of the present invention, the liquid discharge nozzle has a plurality of through holes, d-3, and the coating liquid is simultaneously discharged from the plurality of through holes. Therefore, if a support is placed where the coating liquid is dropped, one coating liquid pattern can be formed without moving the liquid discharge nozzle, which reduces the time required and improves productivity. becomes higher. Further, by appropriately determining the diameter and position of each through hole, the thickness of the formed pattern at each position can be made uniform.

Since it has a large number of through holes, it is suitable for high productivity and coating solutions that do not have a long shelf life, such as those containing enzymes.

[Brief explanation of the drawing]

Fig. 1 is a schematic side view of a pattern coating dispensing device showing an embodiment of the present invention, Fig. 2 is an enlarged sectional view of the mono pump portion of the dispensing device, and Fig. 3 is a line taken along line A-A in Fig. 2. Enlarged sectional view, Figures 4 and 5
Figure 6 is an enlarged sectional view of another embodiment of the nozzle Figure 6 is a plane view F1 of the nozzle using an adapter Figure 7 is a sectional view of Figure 6 Figure 8 is a perspective view showing the adapter Figure 9 is during pattern application FIG. 10 is an explanatory diagram showing slitting locations after coating. Vines 1 times 1...Liquid reservoir, 2...Mono pump, 3...Liquid discharge nozzle, 4...Through hole, 5...Pulse motor, 6...
・Coating liquid supply pump, 7...Robot, 8...Control M
l, 9...Support, 10...Moving table, 11...Discharge device for pattern coating, 12...Development layer, 20...
Adapter Rei 2 Figure Applicant Hiroshi Fujimoto Hiroshi Fujimoto

Claims (1)

[Claims] A pattern coating discharge device for supplying a coating liquid, in which a flow rate control pump is provided below a liquid reservoir and is directly connected to the liquid reservoir, and a liquid discharge nozzle is disposed on the discharge side of the flow rate control pump, and the liquid discharge nozzle is provided with a plurality of liquid discharge nozzles. 1. A discharge device for pattern coating, comprising a through hole and means for opening and closing the through hole.