JPH02168968A - Organism terminal structure - Google Patents
Organism terminal structureInfo
- Publication number
- JPH02168968A JPH02168968A JP63322005A JP32200588A JPH02168968A JP H02168968 A JPH02168968 A JP H02168968A JP 63322005 A JP63322005 A JP 63322005A JP 32200588 A JP32200588 A JP 32200588A JP H02168968 A JPH02168968 A JP H02168968A
- Authority
- JP
- Japan
- Prior art keywords
- syringe
- terminal
- guide body
- organism
- connecting means
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241000894006 Bacteria Species 0.000 abstract description 3
- 238000011109 contamination Methods 0.000 abstract 1
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 5
- 239000010936 titanium Substances 0.000 description 5
- 229910052719 titanium Inorganic materials 0.000 description 5
- 238000010586 diagram Methods 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 239000012530 fluid Substances 0.000 description 3
- 210000001124 body fluid Anatomy 0.000 description 2
- 239000010839 body fluid Substances 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000011347 resin Substances 0.000 description 2
- 229920005989 resin Polymers 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 239000011800 void material Substances 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- 239000003899 bactericide agent Substances 0.000 description 1
- 239000000560 biocompatible material Substances 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 229920001971 elastomer Polymers 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 229910052588 hydroxylapatite Inorganic materials 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 229910052755 nonmetal Inorganic materials 0.000 description 1
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 description 1
- -1 polypropylene Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 229920002379 silicone rubber Polymers 0.000 description 1
- 239000004945 silicone rubber Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Media Introduction/Drainage Providing Device (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
Description
【発明の詳細な説明】 本発明は生体端子に関する。[Detailed description of the invention] The present invention relates to a biological terminal.
生体内外を長期間連通せしめるにすぐれた機能を発揮す
る生体端子が提供された(特開昭58年第47896号
、特開昭58年第162645号、特開昭58年第16
8502号、特開昭58年第200733号)。Bioterminals have been provided that exhibit excellent functionality for long-term communication between the inside and outside of a living body (Japanese Unexamined Patent Publication No. 47896 of 1982, No. 162645 of 1981, and No. 16 of 1981).
No. 8502, Japanese Unexamined Patent Application Publication No. 1983 No. 200733).
生体端子は、幅広い用途を有するにもかかわらず、実用
的な具体構造の解明は未だ不充分である。Although bioterminals have a wide range of uses, their practical specific structures have not yet been fully elucidated.
上記に鑑み本発明は、透析液等の薬液の投与乃至排出、
体液の抽出入等を簡便且つ安定的に行なう為に、生体内
外を細菌に汚染されることなく機械的に連通せしめるに
すぐれた構造を備えた生体端子の提供を目的とする。In view of the above, the present invention provides a method for administering and discharging medicinal solutions such as dialysate,
The purpose of the present invention is to provide a bioterminal having an excellent structure that allows mechanical communication between the inside and outside of a living body without being contaminated by bacteria, in order to easily and stably extract and input body fluids.
以下本発明の実施例を図面を参照して詳細に説明する。Embodiments of the present invention will be described in detail below with reference to the drawings.
端子部(Ol) 第1図に側面を、第7図に上面の図を示した。Terminal part (Ol) A side view is shown in FIG. 1, and a top view is shown in FIG.
端子部(OI)は、アルミナ、カーボン、ハイドロキシ
アパタイト、チタン、TCP、4CP等の生体親和性部
材よりなる中空状の最外層体(11)の内部に、チタン
等よりなる内直(12)を螺着して形成される。螺着は
、最外層体(11)及び内部(12)に設けたネジ部(
IA)で行なわれる。The terminal part (OI) has an inner straight layer (12) made of titanium etc. inside a hollow outermost layer body (11) made of a biocompatible material such as alumina, carbon, hydroxyapatite, titanium, TCP, 4CP, etc. Formed by screwing. Screwing is done using threaded parts (
IA).
最外層体(1■)と内!!(12)の螺合を解除、分離
、又は螺合させる際、治具を挿入回動させる為の4つの
溝(70)が内t! (12)の上部に設けられている
(第7図参照)。The outermost layer body (1■) and the inside! ! There are four grooves (70) inside for inserting and rotating the jig when unscrewing, separating, or screwing (12). (12) (see Fig. 7).
内! (12)外縁には、0リング等のシール(13)
が付設され、最外層体(11)と内直(12)の接触面
をシール(13)で密設することにより、生体外部の水
、細菌等異物の侵入を阻止する。Inside! (12) Seal such as O ring on the outer edge (13)
A seal (13) is attached to the contact surface between the outermost layer body (11) and the inner wall (12) to prevent the intrusion of foreign substances such as water and bacteria outside the living body.
内直(12)の内部には上下に摺動可能な軸(16)と
、この袖(16)を支えるチタン等の軸受け(17)が
形成され、軸(16)上部に固定設置されたシリコーン
ゴムよりなる弁(18)は、バネ(19)によって内直
(12)内側上部の孔部A (20)に圧設されている
。内直(12)上部の側面周囲には、0リング状のシー
ル(14)が付設されている。A shaft (16) that can slide up and down and a bearing (17) made of titanium or the like that supports this sleeve (16) are formed inside the inner straight (12), and a silicone bearing (17) made of titanium or the like is fixedly installed on the upper part of the shaft (16). A valve (18) made of rubber is pressed by a spring (19) into a hole A (20) at the upper inner side of the inner straight (12). An O-ring-shaped seal (14) is attached around the upper side of the inner straight (12).
軸受け(17)には受は通路(15)が数個所穿設され
、更に内!! (12)の下部と最外層体(11)との
間に液溜部(21)が形成されている。The bearing (17) has several passages (15) drilled in it, and further inside! ! A liquid reservoir (21) is formed between the lower part of (12) and the outermost layer body (11).
液溜部(21)にカテーテル(04)接続用のチタン等
よりなる接続チューブ(22)が設けられている。A connecting tube (22) made of titanium or the like for connecting the catheter (04) is provided in the liquid reservoir (21).
最外層体(11)上部周縁には水平に連続した突起部1
(23)が一体的に設けられ、最外層体(11)下部
には水平に連続した突起部2 (24)が設けられてい
る。突起部2 (24)には、複数の貫通孔(25)が
設けられている。突起部+ (23)には凹状のストッ
パー受け(36)が設けられている。The outermost layer body (11) has a horizontally continuous protrusion 1 on the upper periphery.
(23) is integrally provided, and a horizontally continuous protrusion 2 (24) is provided at the bottom of the outermost layer body (11). The protrusion 2 (24) is provided with a plurality of through holes (25). A concave stopper receiver (36) is provided on the protrusion + (23).
端子部(Ol)上部には、ネジ部A (54)が設けら
れている。A screw portion A (54) is provided at the upper portion of the terminal portion (Ol).
端子部(Ol)は、最外層体(11)の中程まで生体皮
膚組織に植設される。The terminal portion (Ol) is implanted into the biological skin tissue up to the middle of the outermost layer body (11).
尚、最外層体(11)は、上記の他、生体親和性部材を
金属、又は樹脂、セラミックス等の非金属で形成した最
外層体表面に、プラズマ被覆等の各種方法でコーティン
グしたものであってしよい。In addition to the above, the outermost layer body (11) may be one in which a biocompatible member is coated on the surface of the outermost layer body made of metal or non-metal such as resin or ceramics by various methods such as plasma coating. It's good.
ガイド体(02)
ポリプロピレン樹脂、PVC等よりなるガイド体(02
)は、上下貫通した筒状体(26)によって形成され、
内面中程には凸部(27)が設けられ、筒状体(2’6
)下部には、囲焼部(28)が形成されている。Guide body (02) Guide body (02) made of polypropylene resin, PVC, etc.
) is formed by a cylindrical body (26) passing through the top and bottom,
A convex portion (27) is provided in the middle of the inner surface, and the cylindrical body (2'6
) A surrounding part (28) is formed at the lower part.
又、第8図に示すように、凸部(27)周辺には、筒状
体(26)下部方向以外を方形状の空隙(I B)が取
り囲み、空隙(IB)がない筒状体(26)の下部方向
には、切込み(IC)が設けである。Further, as shown in FIG. 8, around the convex portion (27), a rectangular void (IB) surrounds the cylindrical body (26) except in the lower direction, and the cylindrical body (IB) without a void (IB) 26) is provided with an incision (IC) in the lower direction.
囲焼部(28)を1−1で切断し、その断面図を第3図
、第4図に示す。The enclosure part (28) was cut along the line 1-1, and its sectional views are shown in FIGS. 3 and 4.
囲焼部(28)周縁には、軸(43)(44)を中心に
左右に開く開き戸(41)(42)が形成され、左右の
開き戸には把手が設けられている。一方の把手B(46
)には係止部(47)が設けられており、把手A(45
)がこの係止部(47)に係合されることにより、開き
戸(41)(42)はとじたまま係止される。囲繞部(
28)は端子部(01)の突起部1 (23)周囲を囲
焼すべく形成されたものであり、囲続部内面の形状は突
起部1 (23)の周囲形状に合わせて形成されている
。又、囲焼部内面にはストッパー(48)が設けられて
いる。ストッパー(48)は、第7図に示す端子部(O
l)のストッパー受け(36)と嵌合する。このことに
より、端子部(01)上でガイド体(02)が回動しな
いように固定される。Swinging doors (41) and (42) that open left and right about shafts (43 and 44) are formed on the periphery of the surrounding part (28), and handles are provided on the left and right swinging doors. One handle B (46
) is provided with a locking part (47), and the handle A (45
) is engaged with this locking portion (47), so that the hinged doors (41) and (42) are locked while remaining closed. Surrounding part (
28) is formed to surround the periphery of the protrusion 1 (23) of the terminal part (01), and the shape of the inner surface of the surrounding part is formed to match the surrounding shape of the protrusion 1 (23). There is. Further, a stopper (48) is provided on the inner surface of the enclosure. The stopper (48) is connected to the terminal portion (O
It fits with the stopper receiver (36) of l). As a result, the guide body (02) is fixed on the terminal portion (01) so as not to rotate.
尚、ガイド体に設けた開き戸(41)(42)は各々に
軸(43)(44)を設けているが、これに限らず、1
つの軸を支点に囲繞部が2つに分かれる形状等も取り得
る。Note that the hinged doors (41) and (42) provided on the guide body each have a shaft (43) and (44); however, the invention is not limited to this.
It is also possible to adopt a shape in which the surrounding part is divided into two parts with one axis as a fulcrum.
シリンジ(03)
第1図に於いて、中空部(34)を宵する筒状シリンジ
本体(29)上部には、十文字方向に水平に延びる掛部
(30)が設けである(第1O図参照)。Syringe (03) In Figure 1, the upper part of the cylindrical syringe body (29) that encloses the hollow part (34) is provided with a hanging part (30) that extends horizontally in the cross direction (see Figure 1O). ).
シリンジ本体(29)下部より中央にかけて、凹部(3
1)がシリンジ本体(29)の長手方向に沿って設けで
ある。凹部(31)は、シリンジ本体(29)下部先端
で段差が設けられており、先端の深い場所を深部(31
A)、浅い場所を浅部(31B)とした。From the bottom of the syringe body (29) to the center, there is a recess (3
1) is provided along the longitudinal direction of the syringe body (29). The recess (31) has a step at the lower tip of the syringe body (29), and the deep part of the tip is connected to the deep part (31).
A), the shallow area was defined as the shallow area (31B).
シリンジ本体(29)中央付近で凹部(31)は、シリ
ンジ本体(29)の長手方向に対して垂直に約半周はど
延びて水平部(31G)を形成している。Near the center of the syringe body (29), the recess (31) extends approximately half a circumference perpendicularly to the longitudinal direction of the syringe body (29) to form a horizontal portion (31G).
シリンジ本体(29)先端(32)付近には、本体(2
9)の中空部(34)と連通した孔部B (33)が設
けられている。Near the tip (32) of the syringe body (29), there is a
A hole B (33) communicating with the hollow part (34) of 9) is provided.
又、シリンジ本体(29)に設けた凹部(31)は、そ
の浅部(31B )を長平方向に沿って形成されている
が、これをらせん状に形成する場合もある。Furthermore, although the shallow portion (31B) of the recess (31) provided in the syringe body (29) is formed along the elongated direction, it may also be formed in a spiral shape.
尚、本発明に於いて、ガイド体、シリンジの材質は特定
するしのではない。In the present invention, the materials of the guide body and the syringe are not specified.
次に動作について説明する。Next, the operation will be explained.
第1図に於いて、予め生体皮膚組織(BO)上に植設さ
れた端子部(Ol)は、最外層体(11)が生体との親
和性を保つことから、植設後2週間程度で皮膚組織と結
合する。In Fig. 1, the terminal part (Ol) implanted in advance on the living body's skin tissue (BO) can be used for about two weeks after implantation because the outermost layer (11) maintains compatibility with the living body. It combines with skin tissue.
シリンジ(03)及びガイド体(02)は結合した状態
で保持される。即ち、結合した状態であればシリンジ(
03)の先端(32)付近を手で触れるようなことがな
く、雑菌等の付着を阻止できるからである。The syringe (03) and the guide body (02) are held in a coupled state. In other words, if they are in a combined state, the syringe (
This is because there is no need to touch the vicinity of the tip (32) of 03) with your hands, and the adhesion of germs and the like can be prevented.
シリンジ(03)及びガイド体(02)の結合は、下注
の通り行なわれる。ガイド体(02)に設けた凸部(2
7)が、切込み(IC)を支点としてガイド体(02)
内外に弾力的に揺動する為、シリンジ(03)が挿入さ
れてから凸部(27)が凹部(31)の深部(31A)
に到達する迄、凸部(27)はガイド体(02)の外側
方向に押され、凹部(31)のfI!部(31,A)に
到達すると、凸部(27)は元に戻る。The syringe (03) and the guide body (02) are coupled as described below. The convex portion (2) provided on the guide body (02)
7) is the guide body (02) with the notch (IC) as the fulcrum.
Since it swings elastically in and out, the convex part (27) moves into the deep part (31A) of the concave part (31) after the syringe (03) is inserted.
The convex portion (27) is pushed outward of the guide body (02) until fI! of the concave portion (31) is reached. When reaching the part (31, A), the convex part (27) returns to its original state.
第3図乃至第4図に示すガイド体(02)の囲繞部(2
8)にある開き戸(41)(42)を開き、端子部(O
l)上部の突起部(23)周辺を囲繞し、把手部B(4
6)の係止部(47)に把手A (45)を係合する。The surrounding part (2) of the guide body (02) shown in Figs.
8) Open the hinged doors (41) and (42), and open the terminal section (O
l) Surround the upper protrusion (23) and handle part B (4
6) engage the handle A (45) with the locking part (47).
又、把手A (45)と把手B (46)の保合を解除
すれば開き戸(41)と(42)は開き、端子部(01
)からガイド体(02)を取り外すことができる。Also, if the engagement between handle A (45) and handle B (46) is released, the hinged doors (41) and (42) will open, and the terminal portion (01) will open.
) from which the guide body (02) can be removed.
端子部(01)にガイド体(02)を囲繞した後、シリ
ンジ(03)を端子部(Oi)方向に押圧する。ガイド
体(02)の凸部(27)は、自身の弾力性から、深部
((IA)から離脱し、浅部(31B)に沿ってシリン
ジ(03)の平行部(31G)の付近に達する。次に若
干の回転を加′えて、凸部(27)を水平部(31C)
に移動させる。シリンジ(03)は上下の移動を阻止さ
れ固定される。After surrounding the guide body (02) around the terminal part (01), the syringe (03) is pressed in the direction of the terminal part (Oi). Due to its own elasticity, the convex part (27) of the guide body (02) separates from the deep part ((IA) and reaches near the parallel part (31G) of the syringe (03) along the shallow part (31B). .Next, by adding a slight rotation, the convex part (27) is moved to the horizontal part (31C).
move it to The syringe (03) is prevented from moving up and down and is fixed.
シリンジ(03)の先端(32)が弁(18)を押圧し
、弁(1g)は下方向へと押しやられる(第2図参照)
。The tip (32) of the syringe (03) presses the valve (18), and the valve (1g) is pushed downward (see Figure 2).
.
内1! (12)に設けられたシール(14)は、シリ
ンジ(03)の周縁と密着する。端子部(01)とシリ
ンジ(03)がガイド体(02)を介して挿入固定され
た後、内部を通る液体の通路は第2図に示す矢印の通り
である。1 of them! The seal (14) provided at (12) is in close contact with the periphery of the syringe (03). After the terminal portion (01) and the syringe (03) are inserted and fixed via the guide body (02), the liquid passage inside is as shown by the arrow in FIG.
外部接続チューブ(05)よりシリンジ(03)の液体
通路(34)を介して流れてきた薬液は、先端(32)
付近の孔部B (33)、受は通路(15)を流れて液
溜(21)に至り、更に、接続チューブ(22)を介し
てカテーテル(04)に流れ込むものである。The drug solution flowing from the external connection tube (05) through the liquid passageway (34) of the syringe (03) is transferred to the tip (32).
Near the hole B (33), the fluid flows through the channel (15) to the reservoir (21) and further into the catheter (04) via the connecting tube (22).
使用後、シリンジ(03)を挿入時と反対方向に回転さ
せて、凸部(27)をシリンジ本体(29)の長平方向
の凹部(31)迄至らしめ、シリンジ(03)を引く。After use, rotate the syringe (03) in the opposite direction to when it was inserted, bring the convex part (27) into the concave part (31) in the longitudinal direction of the syringe body (29), and pull the syringe (03).
凸部(27)は、凹部(31)の深部(31A)’に入
り、その状態でガイド体(02)とシリンジ(03)は
固定される。The convex part (27) enters the deep part (31A)' of the concave part (31), and the guide body (02) and the syringe (03) are fixed in this state.
シリンジ先端(32)によって押されていた弁(18)
は、再びバネ(19)の力によって孔部A (20)I
こ押し当てられる。互いに係合している把手を解除して
、ガイド体(02)を端子(03)上部から取り外す。Valve (18) pressed by syringe tip (32)
is again applied to the hole A (20) I by the force of the spring (19).
This is pushed against me. Release the mutually engaged handles and remove the guide body (02) from the upper part of the terminal (03).
弁(18)が孔部A (20)に押し当てられることに
よって、生体内部への通路は遮断されるが、更に長期間
使用しない場合、第5図に示すようなシリコーンゴム等
よりなるシール(53)を施し、更に殺菌剤(52)を
含有したキャップ(51)をキャップ(51)の内側に
設けたネジ部(55)と端子部(01)のネジ部(54
)とを螺合被着させておけば、より安全に端子部を生体
上に設置しておけるものである。By pressing the valve (18) against the hole A (20), the passage to the inside of the living body is blocked, but if it is not used for a longer period of time, a seal made of silicone rubber or the like as shown in Fig. 5 ( 53), and a cap (51) containing a bactericide (52) is provided inside the cap (51), and the threaded part (54) of the terminal part (01).
), the terminal can be more safely placed on the living body.
又、本発明を繰り返し使用し、端子部(01)内部及び
生体内部に配置したカテーテル(04)等の諸器具を洗
浄殺菌しなければならない場合、本発明では、第9図に
示すように内直(12)の螺合を解除し、代わりに外部
接続チューブ(05)を接続した接続プラグ(90)を
、接続プラグ(90)内に設けたネジ部(91)と端子
部(Ol)との螺着によって端子部(01)上に固定す
ることにより、外部との洗浄、殺菌を目的とする薬液等
の交換が行なえるものである。In addition, when the present invention is repeatedly used and various instruments such as the catheter (04) placed inside the terminal part (01) and inside the living body must be cleaned and sterilized, the present invention allows the internal cleaning as shown in FIG. Unscrew the straight part (12) and connect the connecting plug (90) with the external connecting tube (05) connected instead, between the screw part (91) provided inside the connecting plug (90) and the terminal part (Ol). By fixing it onto the terminal part (01) by screwing it, it is possible to exchange chemicals for the purpose of cleaning and sterilization with the outside.
尚、本発明は、端子部に接続手段を結合させた際、連通
し、透析液等の薬液の投与排出、乃至体液の抽出入を行
なうことができるような構造、及び端子部上に接続手段
を固定させ得るような構造を有するガイド体であれば、
いかなる形状を有してもかまわないものである。例えば
、端子部(Ol)上に設けたネジ部(54)と螺合可能
な形状を有するガイド体、あるいは、第6図に示すよう
な囲繞部を有するガイド体が提示される。Note that the present invention provides a structure that allows communication, administration and discharge of medicinal fluids such as dialysate, and extraction and entry of body fluids when the connecting means is coupled to the terminal portion, and a connecting means on the terminal portion. If the guide body has a structure that can fix the
It may have any shape. For example, a guide body having a shape that can be screwed into a threaded part (54) provided on the terminal part (Ol), or a guide body having a surrounding part as shown in FIG. 6 is proposed.
第6図は、第1図に示すガイド体(02)のr−t′で
切断した断面図に相当する。動作を略説すると次の通り
である。FIG. 6 corresponds to a cross-sectional view of the guide body (02) shown in FIG. 1 taken along the line r-t'. The operation is briefly explained as follows.
把手A (81)、把手B (62)を押圧することに
より、支点(67)を中心に、開き戸(63)(64)
が開き、囲繞部(66)は開放され、端子部が囲繞され
る。By pressing handle A (81) and handle B (62), the hinged door (63) (64) is opened around the fulcrum (67).
is opened, the surrounding portion (66) is opened, and the terminal portion is surrounded.
把手A (61)、把手B (62)の押圧を止めると
、バネ(65)の力によって把手A (61)と把手B
(62)は外側に力が加えられ、支点(67)を中心
に、開き戸(63)(64)は閉じて、ガイド体(02
)は端子部上に固定される。When you stop pressing on handle A (61) and handle B (62), handle A (61) and handle B are pulled apart by the force of the spring (65).
(62) is applied an outward force, the hinged doors (63) and (64) close around the fulcrum (67), and the guide body (02)
) is fixed on the terminal section.
以上詳述の如く本発明は、生体皮膚を介する薬液の投与
交換等を長期間安定的に行なわせしむるに絶大な効果を
有するしのである。As described in detail above, the present invention has a tremendous effect in stably performing the administration and exchange of drug solutions through the skin of a living body over a long period of time.
第1図は、本発明の一実施例を示す図、第2図は、第1
図に示す実施例中、流体の流れを示す動作説明図、第3
図、第4図は、第1図の実施例を上部より見た図、第5
図、第6図、第7図、第8図、第1O図は、第1図に示
す実施例の一部分を示す図である。第9図は、本発明の
他の態様を示す図である。
01・・・・・・・・・・・・端子部、02・・・・・
・・・・・・・ガイド体、03・・・・・・・・・・・
・シリンジ(接続手段)、BO・・・・・・生体皮膚組
織。
特許出願人 株式会社アドノくンス
第1図
第2図
第3図
第6図
第5図
第τ図
第8
図FIG. 1 is a diagram showing one embodiment of the present invention, and FIG. 2 is a diagram showing an embodiment of the present invention.
In the embodiment shown in the figure, the operation explanatory diagram showing the flow of fluid, the third
Figure 4 is a view of the embodiment shown in Figure 1 viewed from above;
6, 7, 8, and 10 are views showing a portion of the embodiment shown in FIG. 1. FIG. 9 is a diagram showing another embodiment of the present invention. 01・・・・・・・・・Terminal part, 02・・・・・・
・・・・・・Guide body, 03・・・・・・・・・・・・
- Syringe (connection means), BO... living body skin tissue. Patent applicant: Adno Kunsu Co., Ltd. Figure 1 Figure 2 Figure 3 Figure 6 Figure 5 Figure τ Figure 8
Claims (1)
子部と着脱自在に設けた接続手段、端子部及び接続手段
を装着して接続手段を端子部上に固定する着脱自在なガ
イド体、前記端子部内に形成され、且つ前記接続手段が
装着される際開口し、接続手段及び端子部面を機械的に
連通せしめる為の弁体よりなることを特徴とする生体端
子構造体。(1) A terminal portion around which a biocompatible member is arranged, a connecting means detachably attached to the terminal portion, and a removable guide body to which the terminal portion and the connecting means are attached and the connecting means is fixed onto the terminal portion. . A bioterminal structure comprising a valve body formed in the terminal portion and opened when the connecting means is attached to mechanically communicate the connecting means and the surface of the terminal portion.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP63322005A JP2732272B2 (en) | 1988-12-22 | 1988-12-22 | Biological terminal structure |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP63322005A JP2732272B2 (en) | 1988-12-22 | 1988-12-22 | Biological terminal structure |
Publications (2)
Publication Number | Publication Date |
---|---|
JPH02168968A true JPH02168968A (en) | 1990-06-29 |
JP2732272B2 JP2732272B2 (en) | 1998-03-25 |
Family
ID=18138858
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP63322005A Expired - Lifetime JP2732272B2 (en) | 1988-12-22 | 1988-12-22 | Biological terminal structure |
Country Status (1)
Country | Link |
---|---|
JP (1) | JP2732272B2 (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH07178170A (en) * | 1993-10-22 | 1995-07-18 | F Hoffmann La Roche Ag | Active material solution injection device |
JP2010510016A (en) * | 2006-11-23 | 2010-04-02 | レニショウ パブリック リミテッド カンパニー | Nervous system device with percutaneous access device |
JP2010220738A (en) * | 2009-03-23 | 2010-10-07 | Sumitomo Bakelite Co Ltd | Connector |
US9662484B2 (en) | 2012-10-02 | 2017-05-30 | Renishaw Plc | Neurosurgical device and method |
US10507316B2 (en) | 2010-02-12 | 2019-12-17 | Renishaw (Ireland) Limited | Implantable fluid router |
-
1988
- 1988-12-22 JP JP63322005A patent/JP2732272B2/en not_active Expired - Lifetime
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH07178170A (en) * | 1993-10-22 | 1995-07-18 | F Hoffmann La Roche Ag | Active material solution injection device |
JP2010510016A (en) * | 2006-11-23 | 2010-04-02 | レニショウ パブリック リミテッド カンパニー | Nervous system device with percutaneous access device |
US8974422B2 (en) | 2006-11-23 | 2015-03-10 | Renishaw (Ireland) Limited | Neurological apparatus comprising a percutaneous access device |
US10751520B2 (en) | 2006-11-23 | 2020-08-25 | Renishaw (Ireland) Limited | Neurological apparatus comprising a percutaneous access device |
US11717663B2 (en) | 2006-11-23 | 2023-08-08 | Renishaw (Ireland) Limited | Neurological apparatus comprising a percutaneous access device |
JP2010220738A (en) * | 2009-03-23 | 2010-10-07 | Sumitomo Bakelite Co Ltd | Connector |
US10507316B2 (en) | 2010-02-12 | 2019-12-17 | Renishaw (Ireland) Limited | Implantable fluid router |
US10596362B2 (en) | 2010-02-12 | 2020-03-24 | Renishaw (Ireland) Limited | Percutaneous drug delivery apparatus |
US11826536B2 (en) | 2010-02-12 | 2023-11-28 | Renishaw (Ireland) Limited | Percutaneous drug delivery apparatus |
US9662484B2 (en) | 2012-10-02 | 2017-05-30 | Renishaw Plc | Neurosurgical device and method |
Also Published As
Publication number | Publication date |
---|---|
JP2732272B2 (en) | 1998-03-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US20220248836A1 (en) | Twist seal oral fluid delivery device | |
US4649904A (en) | Biopsy seal | |
RU2625273C2 (en) | Device for extraction, storage and/or processing of blood or other substances of human or animal origin and for use of blood compounds or other biological compounds | |
JP5734982B2 (en) | Disinfection male luer connector cap | |
US20050147524A1 (en) | Sterile tubing termination assembly | |
US20050147525A1 (en) | Sanitized tubing termination method and assembly | |
US20070161946A1 (en) | Apparatus for applying and removing closing means from an end portion of a tubular element and the use thereof in peritoneal dialysis | |
EP0085692A1 (en) | Antibacterial closure | |
JPH06505658A (en) | Improved intramedullary catheter | |
JP2014505518A (en) | Apparatus, assembly and method for controlling fluid flow | |
KR20180103693A (en) | Packaging vessel for dental implant of breakable coupling type | |
WO1995020409A1 (en) | Implantable dosaging system | |
JP7418521B2 (en) | syringe adapter | |
US20110319842A1 (en) | Antiseptic applicator | |
KR20190102064A (en) | Vessel devices for collecting, storing and processing blood or blood compounds | |
JPH02168968A (en) | Organism terminal structure | |
CN109152626A (en) | Oral-cavity device | |
JPS62500704A (en) | Ports and resilient closures | |
JP2004016437A (en) | Syringe connection port | |
RU2221598C2 (en) | Needleless luer's medical adapter with a drive | |
TWM503228U (en) | Needle-free connector assembly featuring easy-to-wash function | |
KR20100071893A (en) | Cupping glass with air valve | |
AU2020440109B2 (en) | Capped, guided dental implant shield | |
EP2121115B1 (en) | A medical product, and a method of sterilizing a medical product | |
JPH1085341A (en) | Connector with hemostatic valve for catheter |