JPH02152461A - Tissue absorbable film - Google Patents
Tissue absorbable filmInfo
- Publication number
- JPH02152461A JPH02152461A JP63305046A JP30504688A JPH02152461A JP H02152461 A JPH02152461 A JP H02152461A JP 63305046 A JP63305046 A JP 63305046A JP 30504688 A JP30504688 A JP 30504688A JP H02152461 A JPH02152461 A JP H02152461A
- Authority
- JP
- Japan
- Prior art keywords
- tissue
- bleeding
- absorbable
- polymer material
- cow
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002861 polymer material Substances 0.000 claims abstract description 6
- 239000012528 membrane Substances 0.000 claims description 18
- 208000032843 Hemorrhage Diseases 0.000 abstract description 14
- 208000034158 bleeding Diseases 0.000 abstract description 14
- 231100000319 bleeding Toxicity 0.000 abstract description 14
- 230000000740 bleeding effect Effects 0.000 abstract description 14
- 210000001519 tissue Anatomy 0.000 abstract description 9
- 241001465754 Metazoa Species 0.000 abstract description 5
- 210000004072 lung Anatomy 0.000 abstract description 4
- 229920002201 Oxidized cellulose Polymers 0.000 abstract description 3
- 229940107304 oxidized cellulose Drugs 0.000 abstract description 3
- 102000008186 Collagen Human genes 0.000 abstract description 2
- 108010035532 Collagen Proteins 0.000 abstract description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract description 2
- 241001494479 Pecora Species 0.000 abstract description 2
- 229920000954 Polyglycolide Polymers 0.000 abstract description 2
- 210000004204 blood vessel Anatomy 0.000 abstract description 2
- 210000000988 bone and bone Anatomy 0.000 abstract description 2
- 229920001436 collagen Polymers 0.000 abstract description 2
- 210000001951 dura mater Anatomy 0.000 abstract description 2
- 210000002837 heart atrium Anatomy 0.000 abstract description 2
- 210000003205 muscle Anatomy 0.000 abstract description 2
- -1 polydioxane Polymers 0.000 abstract description 2
- 239000004633 polyglycolic acid Substances 0.000 abstract description 2
- 210000004351 coronary vessel Anatomy 0.000 abstract 1
- 230000002439 hemostatic effect Effects 0.000 abstract 1
- 230000002745 absorbent Effects 0.000 description 10
- 239000002250 absorbent Substances 0.000 description 10
- 230000023597 hemostasis Effects 0.000 description 6
- 238000001356 surgical procedure Methods 0.000 description 6
- 230000000694 effects Effects 0.000 description 4
- 239000000853 adhesive Substances 0.000 description 3
- 230000001070 adhesive effect Effects 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 108010080379 Fibrin Tissue Adhesive Proteins 0.000 description 2
- 239000003242 anti bacterial agent Substances 0.000 description 2
- 229940030225 antihemorrhagics Drugs 0.000 description 2
- 238000007675 cardiac surgery Methods 0.000 description 2
- 239000002874 hemostatic agent Substances 0.000 description 2
- 229920001651 Cyanoacrylate Polymers 0.000 description 1
- MWCLLHOVUTZFKS-UHFFFAOYSA-N Methyl cyanoacrylate Chemical compound COC(=O)C(=C)C#N MWCLLHOVUTZFKS-UHFFFAOYSA-N 0.000 description 1
- 230000003872 anastomosis Effects 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 210000001185 bone marrow Anatomy 0.000 description 1
- 238000005266 casting Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 210000005240 left ventricle Anatomy 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 210000001147 pulmonary artery Anatomy 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 210000005245 right atrium Anatomy 0.000 description 1
- 210000005241 right ventricle Anatomy 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Abstract
Description
【発明の詳細な説明】
〔技術分野〕
本発明は、手術後の処置を迅速、適確に行うために使用
する医療用組織吸収性膜に関する。DETAILED DESCRIPTION OF THE INVENTION [Technical Field] The present invention relates to a medical tissue-absorbable membrane used for rapid and accurate post-surgical treatment.
切開手術における切り口の処理方法としては古くから縫
合、抜糸の方法が採られてきたが、近年吸収性縫合糸に
よる縫合を行い抜糸の必要でないことも多い。Suturing and suture removal have long been used as a method for treating incisions in incisional surgery, but in recent years suturing with absorbable sutures has often eliminated the need for suture removal.
しかしながら、これはあくまでも縫合であるため傷口が
完全にシールされているわけではないから、傷口からの
出血が術後の回復に悪影響をおよぼすことがある。又、
肺の手術においては、傷口からの空気もれがおこり、や
はり好ましくない影響を与える。このような場合には、
可吸収性創腔充填止血剤が使用されてきた。これは例え
ば酸化セルロースからなる綿状のもので、これを出血部
にはりつけて使用していた。また、もう１つの止血方法
としては接着剤例えば、フィブリン糊、ビオボンド、シ
アノアクリレートなどを出血部位に塗りつける方法であ
った。ところが、いずれの方法を採っても処置に時間が
かかったり、出血の圧力が大きい場合には全く止血効果
がないなど満足す八き効果をあげることができなかった
。また、組織面から出血傾向をともなって、出血する場
合、これら接着剤の塗布のみでは止血が困難である。However, since this is just a suture, the wound is not completely sealed, so bleeding from the wound may have a negative impact on post-surgery recovery. or,
In lung surgery, air leaks from the wound, which also has undesirable effects. In such a case,
Absorbable wound filler hemostatic agents have been used. This is a cotton-like material made of oxidized cellulose, for example, and was used by attaching it to the bleeding area. Another method for stopping bleeding is to apply an adhesive such as fibrin glue, Biobond, or cyanoacrylate to the bleeding site. However, no matter which method is used, the treatment takes a long time, and when the pressure of bleeding is large, there is no hemostasis effect at all, and the results are not satisfactory. In addition, when bleeding occurs from the tissue surface with a tendency to bleed, it is difficult to stop the bleeding only by applying these adhesives.
本発明の目的は、極めて簡便に充分満足できる止血効果
を持つ止血部材を提供する点にある。An object of the present invention is to provide a hemostasis member that is extremely simple and has a fully satisfactory hemostasis effect.
本発明は、組織吸収性高分子材料よりなる医療用組織吸
収性膜に関する。The present invention relates to a medical tissue absorbable membrane made of a tissue absorbable polymer material.
前記組織吸収性高分子材料としては、動物（例えば、牛
、羊等）の腸、牛等の動物の真皮コラーゲン塩酸塩、ポ
リグリコール酸、ポリジオフサノン、酸化セルロースポ
リグラチン９１０等を例示することができる。Examples of the tissue-absorbable polymer material include animal (e.g., cow, sheep, etc.) intestine, cow and other animal dermal collagen hydrochloride, polyglycolic acid, polydiophsanone, oxidized cellulose polyglatine 910, etc. can.
本発明の吸収性膜は、傷口が小さければ縫合することな
く貼り付けるのみでよいし、傷口が大きい場合には縫合
糸で縫合した後、吸収性膜を貼り付けるのがよい。本発
明の吸収性膜の貼り付けはフィブリン糊などの接着剤を
使用して接着してもよい。If the wound is small, the absorbent membrane of the present invention may be simply pasted on without suturing it, or if the wound is large, it may be sutured with sutures and then the absorbent membrane is pasted on. The absorbent membrane of the present invention may be attached using an adhesive such as fibrin glue.
膜の厚みは、耐圧力が使用環境下で最大５０ｍｍ）Ｉｇ
の圧力に耐えられる厚みであればできるだけ薄い方が好
ましい。又、本発明の吸収性膜はその使用目的からでき
るだけ軟らかい性質をもつ材料を選択することが好まし
い。The maximum pressure resistance of the membrane is 50 mm under the operating environment)Ig
As long as the thickness can withstand the pressure, it is preferable to make it as thin as possible. Furthermore, it is preferable to select a material for the absorbent membrane of the present invention that is as soft as possible in view of its intended use.
本発明の吸収性膜は、筋肉面からの小さな無数の出血に
対する止血用、肺の縫合部からの空気もれ防止のほか、
心房の切開部所、血管壁縫合部、冠状動脈吻合部の切開
部所に対する止血用、硬膜からの出血のための止血用、
骨片採取部の骨髄からの出血のための止血用、あるいは
組織に対する一時的保護用として極めて有用である。The absorbable membrane of the present invention can be used to stop numerous small bleedings from muscle surfaces, to prevent air leakage from sutures in the lungs, and to
For hemostasis at incisions in the atrium, blood vessel wall sutures, incisions in coronary anastomoses, and for bleeding from the dura mater.
It is extremely useful for stopping bleeding from the bone marrow at the site where bone fragments have been harvested, or for temporarily protecting tissues.
本発明の吸収性膜の用途はこれに限定されるものではな
く、広く動物のための止血用、空気もれ用、組織保護用
として使用することができる。The use of the absorbent membrane of the present invention is not limited to this, but can be widely used for hemostasis, air leakage, and tissue protection for animals.
本発明の吸収性膜中に必要に応じて抗生物質等の抗菌剤
、止血剤等を配合しておくこともできるし、又、吸収性
高分子物質の分子にあらかじめ薬剤分子を結合させてお
いて使用することができる。If necessary, antibacterial agents such as antibiotics, hemostatic agents, etc. can be mixed into the absorbent membrane of the present invention, or drug molecules can be bonded to molecules of the absorbent polymer substance in advance. can be used.
吸収性膜の成形は通常の高分子物質による膜状物の成形
手段を使用することができるが、通常、流延成形又は押
出成形法による。The absorbent membrane can be formed using conventional means for forming membranes using polymeric materials, and is usually formed by casting or extrusion.
本発明の吸収性膜の使用により１手術後の止血処置、空
気もれ処置が短時間に、極めて効果的に遂行することが
でき、術後の仕上りも極めてきれいにすることができる
。By using the absorbent membrane of the present invention, hemostasis treatment and air leakage treatment after one surgery can be carried out very effectively in a short period of time, and the post-surgery finish can also be extremely clean.
図面は本発明の吸収性膜の使用態様を示す。
第１図は、心臓の手術後に本発明の吸収性膜を適用した
態様を示し、第２図は、師の手術後に本発明の吸収性膜
を適用した態様を示すものである。
１・・・吸収性膜 ２・・・切開部３・・・右心房
４・・・肺動脈５・・・左心室 ６・・
・右心室７・・・肺
兜１図The drawings illustrate the use of the absorbent membrane of the invention. FIG. 1 shows an embodiment in which the absorbable membrane of the present invention is applied after cardiac surgery, and FIG. 2 shows an embodiment in which the absorbable membrane of the present invention is applied after cardiac surgery. 1... Absorbable membrane 2... Incision 3... Right atrium 4... Pulmonary artery 5... Left ventricle 6...
・Right ventricle 7...Lung helmet 1 diagram
Claims (1)
。1. Medical tissue-absorbable membrane made of tissue-absorbable polymer material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP63305046A JPH02152461A (en) | 1988-12-01 | 1988-12-01 | Tissue absorbable film |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP63305046A JPH02152461A (en) | 1988-12-01 | 1988-12-01 | Tissue absorbable film |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH02152461A true JPH02152461A (en) | 1990-06-12 |
Family
ID=17940461
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP63305046A Pending JPH02152461A (en) | 1988-12-01 | 1988-12-01 | Tissue absorbable film |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH02152461A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2668936A1 (en) * | 1990-11-09 | 1992-05-15 | Eberlin Jean Luc | Graft based on collagen and fibrin adhesive for osseocartilaginous reconstruction, and method for its preparation |
| WO1999020320A1 (en) * | 1997-10-22 | 1999-04-29 | Gunze Limited | Artificial dura |
| US7041713B2 (en) | 2000-04-28 | 2006-05-09 | Gunze Limited | Artificial dura mater |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5142878A (en) * | 1974-10-08 | 1976-04-12 | Nippon Spindle Mfg Co Ltd | YUATSUSHIKIHATSUSHINSOCHI |
| JPS60153868A (en) * | 1983-12-19 | 1985-08-13 | サウザン・リサーチ・インスチチユート | Biologically decomposable artificial accessory and its production |
| JPS6369825A (en) * | 1986-09-11 | 1988-03-29 | Mitsui Toatsu Chem Inc | Block copolymer and production thereof |
| JPS63145660A (en) * | 1986-09-05 | 1988-06-17 | アメリカン・サイアナミド・カンパニー | Coating of surgical filament |
| JPH0263465A (en) * | 1988-08-31 | 1990-03-02 | G C Dental Ind Corp | Tooth surrounding tissue reproduction material |
| JPH03503371A (en) * | 1988-03-15 | 1991-08-01 | イムデックス | visceral surgery patch |
| JPH03505535A (en) * | 1988-07-05 | 1991-12-05 | ビオコン オーワイ | Polymer film for reinforced biofunctional materials |
-
1988
- 1988-12-01 JP JP63305046A patent/JPH02152461A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5142878A (en) * | 1974-10-08 | 1976-04-12 | Nippon Spindle Mfg Co Ltd | YUATSUSHIKIHATSUSHINSOCHI |
| JPS60153868A (en) * | 1983-12-19 | 1985-08-13 | サウザン・リサーチ・インスチチユート | Biologically decomposable artificial accessory and its production |
| JPS63145660A (en) * | 1986-09-05 | 1988-06-17 | アメリカン・サイアナミド・カンパニー | Coating of surgical filament |
| JPS6369825A (en) * | 1986-09-11 | 1988-03-29 | Mitsui Toatsu Chem Inc | Block copolymer and production thereof |
| JPH03503371A (en) * | 1988-03-15 | 1991-08-01 | イムデックス | visceral surgery patch |
| JPH03505535A (en) * | 1988-07-05 | 1991-12-05 | ビオコン オーワイ | Polymer film for reinforced biofunctional materials |
| JPH0263465A (en) * | 1988-08-31 | 1990-03-02 | G C Dental Ind Corp | Tooth surrounding tissue reproduction material |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2668936A1 (en) * | 1990-11-09 | 1992-05-15 | Eberlin Jean Luc | Graft based on collagen and fibrin adhesive for osseocartilaginous reconstruction, and method for its preparation |
| WO1999020320A1 (en) * | 1997-10-22 | 1999-04-29 | Gunze Limited | Artificial dura |
| US6679919B2 (en) | 1997-10-22 | 2004-01-20 | Gunze Limited | Artificial dura |
| US7041713B2 (en) | 2000-04-28 | 2006-05-09 | Gunze Limited | Artificial dura mater |
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