JPH02102661A - Heat exchanger for medical treatment - Google Patents
Heat exchanger for medical treatmentInfo
- Publication number
- JPH02102661A JPH02102661A JP63254653A JP25465388A JPH02102661A JP H02102661 A JPH02102661 A JP H02102661A JP 63254653 A JP63254653 A JP 63254653A JP 25465388 A JP25465388 A JP 25465388A JP H02102661 A JPH02102661 A JP H02102661A
- Authority
- JP
- Japan
- Prior art keywords
- housing
- hollow core
- heat
- blood
- communicating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008280 blood Substances 0.000 claims abstract description 37
- 210000004369 blood Anatomy 0.000 claims abstract description 37
- 238000005192 partition Methods 0.000 claims abstract description 10
- 229920000642 polymer Polymers 0.000 abstract description 2
- 230000005540 biological transmission Effects 0.000 abstract 1
- 238000004382 potting Methods 0.000 abstract 1
- 230000010412 perfusion Effects 0.000 description 6
- 229910001220 stainless steel Inorganic materials 0.000 description 5
- 239000010935 stainless steel Substances 0.000 description 5
- 230000017531 blood circulation Effects 0.000 description 4
- 230000005465 channeling Effects 0.000 description 4
- 239000004743 Polypropylene Substances 0.000 description 2
- 239000011248 coating agent Substances 0.000 description 2
- 238000000576 coating method Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- -1 polypropylene Polymers 0.000 description 2
- 229920001155 polypropylene Polymers 0.000 description 2
- 241000283690 Bos taurus Species 0.000 description 1
- 206010020843 Hyperthermia Diseases 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 230000015271 coagulation Effects 0.000 description 1
- 238000005345 coagulation Methods 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 239000003822 epoxy resin Substances 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000036031 hyperthermia Effects 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000006213 oxygenation reaction Methods 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 229920000647 polyepoxide Polymers 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- 229920005749 polyurethane resin Polymers 0.000 description 1
- 229920002050 silicone resin Polymers 0.000 description 1
- 238000004381 surface treatment Methods 0.000 description 1
- 238000000015 thermotherapy Methods 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
Abstract
Description
【発明の詳細な説明】
(産業上の利用分野)
本発明は1人工肺、全身温療法等において、血液の熱交
換に用いられる熱交換器、特に伝熱管の外部に血液を流
す外部潅流型の熱交換器に関するものである。Detailed Description of the Invention (Industrial Application Field) The present invention relates to a heat exchanger used for heat exchange of blood in artificial lungs, whole body thermotherapy, etc., particularly an external perfusion type in which blood flows outside a heat transfer tube. The present invention relates to a heat exchanger.
(従来の技術〉
従来よシ入工肺、全身温療法等において体外循環血液回
路に血液の加温、冷却のため種々の形式の熱交換器が広
く用いられている。例えば、ステンレスパイプからなる
多数の伝熱管を円筒状ハウジング内に収容し、その両端
部が開口するようにハウジングの両端を閉塞するプラス
チック製の隔壁で支持し、伝熱管の内部に血液を流し、
伝熱管の外部に伝熱媒体を流す内部潅流型の多管式熱父
換器が臨床的に広く用いられている。(Prior art) Various types of heat exchangers have been widely used for heating and cooling blood in extracorporeal circulation blood circuits in conventional lung oxygenation, whole-body hyperthermia, etc.For example, heat exchangers made of stainless steel pipes A large number of heat exchanger tubes are accommodated in a cylindrical housing, supported by plastic partition walls that close both ends of the housing so that both ends thereof are open, and blood is allowed to flow inside the heat exchanger tubes.
Internal perfusion type multi-tube heat exchangers that flow a heat transfer medium outside the heat transfer tubes are widely used clinically.
(発明が解決しようとする課題)
かかる内部潅流型の熱交換器では血液を多数の伝熱管に
均等に分配供給すれば血液のチャンネリング(偏流)は
ないものの、伝熱管の内部を流れる血液は完全な層流で
あυ、熱交換能(単位伝熱面積当シの熱移動速度)を上
げるためには伝熱管の内径を小さくすることが必要であ
る。しかしながら、ステンレス管の内径を小さくしても
血液が層流状態で流動する限りは熱交換能が飛躍的に向
上するものではない。またこの型の熱交換器はステンレ
ス管を精度高く所定の長さに切断することが困難で、切
断加工表面は粗面化されており、血液損傷を招く結果と
なっている。(Problems to be Solved by the Invention) In such an internal perfusion type heat exchanger, if blood is evenly distributed and supplied to a large number of heat transfer tubes, there will be no blood channeling (unbalanced flow); Since the flow is completely laminar υ, it is necessary to reduce the inner diameter of the heat transfer tube in order to increase the heat exchange capacity (heat transfer rate per unit heat transfer area). However, even if the inner diameter of the stainless steel tube is reduced, the heat exchange performance will not be dramatically improved as long as blood flows in a laminar flow state. Furthermore, in this type of heat exchanger, it is difficult to cut the stainless steel tube to a predetermined length with high precision, and the cutting surface is roughened, resulting in blood damage.
これに対して、伝熱管の外部に血液を流す外部潅流方式
は血液を損傷する恐れが極めて少なく、かつ熱媒体の分
配は良好であり、しかも血液の流れに乱れが発生するこ
とが期待されるものの、血液のチャンネリングによる熱
交換能の低下1あるいは血液の滞留部において凝固が生
じすいという問題がある。したがって本発明の目的は優
れた熱交換能を有し1かっ血液の滞留やチャンネリング
がなく、シかも圧力損失が少なくて血液充填量の少ない
コンパクトな熱変換器を提供することである0
(課題を解決するための手段)
本発明者らは、上記目的を達成するため、血液損傷がな
く、かつ圧力損失が小さく、シかも単位面積当たシのガ
ス交換能の向上が期待される外部潅流型の熱交換器に着
目し、外部潅流型の熱交換器の欠点である血液のチャン
ネリングと血液の滞留を防止するため鋭意検討した結果
本発明に到達したものである。すなわち本発明は上部側
壁に血液出口を有する円筒状のハウジングの中心に中空
芯管を立設し、該ハウジングと中空芯管で形成される熱
交換室に、多数の伝熱管を収容して、そのつ
両端部が開口するように、ハ・ジンクの両端を閉塞する
隔壁で支持し、かつ該中空芯管の下部に熱交換室と連通
ずる開口を穿設するとともに、該ハウジングの上端に伝
熱管の内部空間と連通ずる熱媒体入口と、該中空芯管の
内部と連通ずる血液入口を有する上部へラドカバーを設
け、該ハウジングの下端に伝熱管の内部空間と連通ずる
熱媒体出口を有する下部へラドカバーを設けたことを特
徴とする医療用の熱交換器である。On the other hand, the external perfusion method, in which blood flows outside the heat transfer tube, has very little risk of damaging the blood, and the distribution of the heat medium is good, but it is expected that turbulence will occur in the blood flow. However, there are problems such as a decrease in heat exchange performance due to blood channeling or a tendency for coagulation to occur in the blood retention area. Therefore, an object of the present invention is to provide a compact heat converter that has excellent heat exchange ability, has no blood stagnation or channeling, has low pressure loss, and has a small blood filling volume. Means for Solving the Problems) In order to achieve the above object, the present inventors have developed an external device that does not cause blood damage, has low pressure loss, and is expected to improve the gas exchange capacity per unit area. The present invention was achieved by focusing on perfusion type heat exchangers and conducting intensive studies to prevent blood channeling and blood stagnation, which are disadvantages of external perfusion type heat exchangers. That is, in the present invention, a hollow core tube is installed upright in the center of a cylindrical housing having a blood outlet on the upper side wall, and a large number of heat transfer tubes are housed in a heat exchange chamber formed by the housing and the hollow core tube. At the same time, the H-zinc is supported by a partition wall that closes both ends so that both ends are open, and an opening communicating with the heat exchange chamber is bored in the lower part of the hollow core tube, and an opening communicating with the heat exchange chamber is formed in the lower part of the hollow core tube. A rad cover is provided at an upper portion having a heat medium inlet communicating with the internal space of the heat transfer tube and a blood inlet communicating with the inside of the hollow core tube, and a lower portion having a heat medium outlet communicating with the internal space of the heat transfer tube at the lower end of the housing. This is a medical heat exchanger characterized by being equipped with a heat exchanger.
(作用)
本発明の熱交換器は、中空芯管とハウジングで形成され
る熱交換室に多数の伝熱管を収納し、血液を中空芯管の
下部に穿設された開口から上部に向かって流すようにし
ている。そのため伝熱管の上部から下部に向かって流れ
る熱媒体と向流に近い状態で接触して、熱変換能が向上
する。(Function) The heat exchanger of the present invention accommodates a large number of heat transfer tubes in a heat exchange chamber formed by a hollow core tube and a housing, and directs blood from an opening bored at the bottom of the hollow core tube toward the top. I try to let it flow. Therefore, it comes into contact with the heat medium flowing from the top to the bottom of the heat transfer tube in a nearly countercurrent state, improving heat conversion performance.
(実施例) 次に本発明の熱又換器の一実施例を図面にて説明する。(Example) Next, an embodiment of the heat exchanger of the present invention will be described with reference to the drawings.
第1図は熱交換器の断面図であシ、円筒状のハウジング
1と該ハウジングの中心に立設された中空芯管2との間
に熱交換室が形成されている。そして該熱交換室に多数
のステンレスパイプ等からなる伝熱管3が中空芯管と平
行に収容されている。上記伝熱管3は、その両端が開口
するようにハウジングの両端を閉塞するポリフレタン。FIG. 1 is a sectional view of a heat exchanger, in which a heat exchange chamber is formed between a cylindrical housing 1 and a hollow core tube 2 erected at the center of the housing. A large number of heat transfer tubes 3 made of stainless steel pipes or the like are housed in the heat exchange chamber in parallel with the hollow core tube. The heat exchanger tube 3 is made of polyurethane with both ends of the housing closed so that both ends are open.
シリコーン、エポキシ樹脂等の高分子ボッティング剤の
隔壁6.6′で支持されている。ハウジングの上端は伝
熱管3の内部空間と連通ずる熱媒体入口lOと、中空芯
管2の内部と連通ずる血液人口11を有する上部へラド
カバ−7で覆われている。It is supported by partition walls 6 and 6' made of a polymeric botting agent such as silicone or epoxy resin. The upper end of the housing is covered with an upper rad cover 7 having a heat medium inlet lO communicating with the interior space of the heat transfer tube 3 and a blood port 11 communicating with the interior of the hollow core tube 2.
またハウジング1の下端は伝熱管3の内部空間と連通す
る熱媒体出口13を有する下部ヘッドカバー8で覆われ
ている。Further, the lower end of the housing 1 is covered with a lower head cover 8 having a heat medium outlet 13 communicating with the internal space of the heat transfer tube 3.
中空芯管2の下部には中空芯管2の内部と熱交換室と門
連通する開口9が穿設されている。また円筒状・・ウジ
ング1の上部側壁には熱交換室と連通ずる血液出口19
が設けられている。ハウジング1の血液出口部に隔壁1
4を設け、該隔壁14の上部に血液出口部と熱交換室と
を連通ずる開口を穿設してもよい。An opening 9 is bored in the lower part of the hollow core tube 2 to communicate with the inside of the hollow core tube 2 and the heat exchange chamber. In addition, the upper side wall of the cylindrical housing 1 has a blood outlet 19 that communicates with the heat exchange chamber.
is provided. A partition wall 1 is provided at the blood outlet portion of the housing 1.
4 may be provided, and an opening may be provided in the upper part of the partition wall 14 to communicate the blood outlet section and the heat exchange chamber.
血液人口11は第2図に示すようK、上部へラドカバー
7の内部を円周状の分割片14で2分割し、該分割され
たヘッドカバーの内側空間に血液人口11を開口させ、
しかも中空芯管2の上部を閉塞する隔壁6にヘッドカバ
ーの内側空間と中空芯管2の内部とを連通ずる開口15
を設けてもよい。さらに第3図に示すように中空芯管2
の下端を閉塞する隔壁6′から血液案内具16を中空芯
管の内部に液密に挿入固定してもよい。上記血液と接触
する円筒状ハウジング1の内壁、中空芯管2の内外壁及
び伝熱管3の外壁の表面はできるだけ平滑に仕上げてお
くことが好ましい。金属表面はパフ仕上げ等の機械的な
表面処理よシ平滑に仕上げることかできる。また機械的
な表面仕上げの代わシ、tたは表面仕上げを行った後表
面にシリコーン等の高分子被膜を形成してもよい。その
場合被膜はその成分が血液に溶出したシ、剥離したシす
るものであってはならず、しかも丈夫なものでなければ
ならない。The blood population 11 is as shown in FIG.
Moreover, an opening 15 in the partition wall 6 that closes the upper part of the hollow core tube 2 communicates the inner space of the head cover with the inside of the hollow core tube 2.
may be provided. Furthermore, as shown in Fig. 3, the hollow core tube 2
The blood guide device 16 may be inserted and fixed in a liquid-tight manner into the hollow core tube through the partition wall 6' that closes the lower end of the tube. It is preferable that the surfaces of the inner wall of the cylindrical housing 1, the inner and outer walls of the hollow core tube 2, and the outer wall of the heat exchanger tube 3, which come into contact with the blood, are finished as smooth as possible. Metal surfaces can be finished smooth by mechanical surface treatments such as puff finishing. Alternatively, instead of mechanical surface finishing, a polymer coating such as silicone may be formed on the surface after surface finishing. In this case, the coating must not have its components eluted into blood or peel off, and must be durable.
次に本発明者らは、本発明の熱交換器の効果を確認する
ために、以下の実験を行った。Next, the present inventors conducted the following experiment in order to confirm the effects of the heat exchanger of the present invention.
実験例
外径93.厚さ2.511mのポリプロピレン製のノ1
ウジング内に外径13、厚さ2.5簡のポリプロピレン
製の中空芯管を立設し、該ハウジングと中空芯管で形成
される熱又換器に内径4.011.厚さ0.25■、有
効長7Wmのステンレス管を160本収容して、・・ウ
ジングの両端を閉塞するポリウレタン樹脂よりなる陥壁
に支持させて、第1図に示すような構造の伝熱面積0.
14m”の熱交換器を製作した。Experimental exception diameter 93. Made of polypropylene with a thickness of 2.511 m
A hollow core tube made of polypropylene with an outer diameter of 13 mm and a thickness of 2.5 mm is erected inside the housing, and a heat exchanger formed by the housing and the hollow core tube has an inner diameter of 4.01 mm. 160 stainless steel tubes with a thickness of 0.25 mm and an effective length of 7 Wm are accommodated, supported by a recessed wall made of polyurethane resin that closes both ends of the housing, and the heat transfer structure is as shown in Figure 1. Area 0.
A 14m" heat exchanger was manufactured.
一方中空芯管を設けない熱交換器を別に製作した。On the other hand, we separately manufactured a heat exchanger without a hollow core tube.
上記2種類の熱又換器を37℃に加温された牛血液を用
いて熱又換器性能評価基準(人工肺性能熱管外部に供給
し、温水をl 5 l/minで伝熱管内部に供給した
。The above two types of heat exchangers were tested using bovine blood heated to 37°C to evaluate heat exchanger performance (oxygenator performance). supplied.
(発明の効果)
以上のように本発明の熱交換器は血液を伝熱管の外部に
流し、しかも血液を中空芯管の下部に穿設された開口か
ら伝熱管の外部を上部に向って流すようKしたため、伝
熱管内部を下部に向って流れる熱媒体と向流に近い状態
で接触させることができて、実験例に示すような高い熱
交換能を得ることができる。また本発明の熱交換器は血
液との全ての接触面を平滑にすることができるため血液
損傷のない、極めて安全性の高い熱交換器である6(Effects of the Invention) As described above, the heat exchanger of the present invention allows blood to flow outside the heat exchanger tube, and moreover, allows the blood to flow upward from the outside of the heat exchanger tube through the opening bored at the bottom of the hollow core tube. Because of this, the inside of the heat transfer tube can be brought into contact with the heat medium flowing downward in a nearly countercurrent state, and a high heat exchange performance as shown in the experimental example can be obtained. In addition, the heat exchanger of the present invention is an extremely safe heat exchanger that does not cause blood damage because all contact surfaces with blood can be made smooth6.
第1図〜第3図は本発明の医療用の熱交換器の断面図で
ある。
1・・・・・・・・・ハウジング
2・・・・・・・・・中空芯管
3・・・・・・・・・伝熱管
6.6′°°°°゛°隔 壁
7・・・・・・・・・上部へラドカバー図面の浄書(内
容(=変更なし)
第 1 図
10・・・・・・・・・熱媒体入口
11・・・・・・・・・血液入口
13・・・・・・・・・熱媒体出口
19 勤爪ヱO
特許出願人 株式会社 り ラ し1 to 3 are cross-sectional views of the medical heat exchanger of the present invention. 1...Housing 2...Hollow core tube 3...Heat transfer tube 6.6'°°°°゛°Partition wall 7. ...... Engraving of Rad cover drawing to the top (Contents (=no changes) 1st Figure 10...Heat medium inlet 11...Blood inlet 13 ...Heat medium outlet 19 Kinzume O Patent applicant Rira Shi Co., Ltd.
Claims (1)
に中空芯管を立設し、該ハウジングと中空芯管で形成さ
れる熱交換室に、多数の伝熱管を収容して、その両端部
が開口するように、ハウジングの両端を閉塞する隔壁で
支持し、かつ該中空芯管の下部に熱交換室と連通する開
口を穿設するとともに、該ハウジングの上端に伝熱管の
内部空間と連通する熱媒体入口と、該中空芯管の内部と
連通する血液入口を有する上部ヘッドカバーを設け、該
ハウジングの下端に伝熱管の内部空間と連通する熱媒体
出口を有する下部ヘッドカバーを設けたことを特徴とす
る医療用の熱交換器。A hollow core tube is placed upright in the center of a cylindrical housing having a blood outlet on the upper side wall, and a large number of heat transfer tubes are housed in a heat exchange chamber formed by the housing and the hollow core tube. The housing is supported by partition walls that close both ends of the housing so as to be open, and an opening communicating with the heat exchange chamber is provided at the lower part of the hollow core tube, and an opening communicating with the internal space of the heat exchanger tube is formed at the upper end of the housing. An upper head cover having a heat medium inlet and a blood inlet communicating with the inside of the hollow core tube is provided, and a lower head cover having a heat medium outlet communicating with the internal space of the heat transfer tube is provided at the lower end of the housing. medical heat exchanger.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP63254653A JP2792049B2 (en) | 1988-10-07 | 1988-10-07 | Medical heat exchanger |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP63254653A JP2792049B2 (en) | 1988-10-07 | 1988-10-07 | Medical heat exchanger |
Publications (2)
Publication Number | Publication Date |
---|---|
JPH02102661A true JPH02102661A (en) | 1990-04-16 |
JP2792049B2 JP2792049B2 (en) | 1998-08-27 |
Family
ID=17268001
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP63254653A Expired - Lifetime JP2792049B2 (en) | 1988-10-07 | 1988-10-07 | Medical heat exchanger |
Country Status (1)
Country | Link |
---|---|
JP (1) | JP2792049B2 (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6558848B1 (en) | 1995-03-17 | 2003-05-06 | Canon Kabushiki Kaisha | Electrodes for secondary cells, process for their production, and secondary cells having such electrodes |
JP2010139192A (en) * | 2008-12-15 | 2010-06-24 | Honda Motor Co Ltd | Humidifier |
WO2013013647A1 (en) | 2011-07-22 | 2013-01-31 | UNIVERZITA KARLOVA V PRAZE Lékarská fakulta v Plzni | Heat exchanger with laminarizer |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS61285396A (en) * | 1985-06-12 | 1986-12-16 | Mitsubishi Rayon Co Ltd | Manufacture of multi-tube type heat exchanger |
-
1988
- 1988-10-07 JP JP63254653A patent/JP2792049B2/en not_active Expired - Lifetime
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS61285396A (en) * | 1985-06-12 | 1986-12-16 | Mitsubishi Rayon Co Ltd | Manufacture of multi-tube type heat exchanger |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6558848B1 (en) | 1995-03-17 | 2003-05-06 | Canon Kabushiki Kaisha | Electrodes for secondary cells, process for their production, and secondary cells having such electrodes |
JP2010139192A (en) * | 2008-12-15 | 2010-06-24 | Honda Motor Co Ltd | Humidifier |
WO2013013647A1 (en) | 2011-07-22 | 2013-01-31 | UNIVERZITA KARLOVA V PRAZE Lékarská fakulta v Plzni | Heat exchanger with laminarizer |
US9500415B2 (en) | 2011-07-22 | 2016-11-22 | Univerzita Karlova V Praze Lekarska Fakulta V Plzni | Heat exchanger with laminarizer |
Also Published As
Publication number | Publication date |
---|---|
JP2792049B2 (en) | 1998-08-27 |
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