JPH0134999B2 - - Google Patents

Info

Publication number
JPH0134999B2
JPH0134999B2 JP54167439A JP16743979A JPH0134999B2 JP H0134999 B2 JPH0134999 B2 JP H0134999B2 JP 54167439 A JP54167439 A JP 54167439A JP 16743979 A JP16743979 A JP 16743979A JP H0134999 B2 JPH0134999 B2 JP H0134999B2
Authority
JP
Japan
Prior art keywords
ala
glycerol
alanyl
mycolate
compound according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP54167439A
Other languages
English (en)
Japanese (ja)
Other versions
JPS55113752A (en
Inventor
Rufuransheeru Pieeru
Redere Edogaa
Joei Jan
Shedei Rui
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ANBAARU AJANSU NASHIONARU DO BARORIZASHION DO RA RUSHERUSHU
Original Assignee
ANBAARU AJANSU NASHIONARU DO BARORIZASHION DO RA RUSHERUSHU
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ANBAARU AJANSU NASHIONARU DO BARORIZASHION DO RA RUSHERUSHU filed Critical ANBAARU AJANSU NASHIONARU DO BARORIZASHION DO RA RUSHERUSHU
Publication of JPS55113752A publication Critical patent/JPS55113752A/ja
Publication of JPH0134999B2 publication Critical patent/JPH0134999B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP16743979A 1978-12-22 1979-12-22 Novel compound containing peptidisyl or aminoacyl residue bonded to lipophilic group and pharmaceutic composition containing it Granted JPS55113752A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7849887 1978-12-22

Publications (2)

Publication Number Publication Date
JPS55113752A JPS55113752A (en) 1980-09-02
JPH0134999B2 true JPH0134999B2 (enExample) 1989-07-21

Family

ID=10501920

Family Applications (1)

Application Number Title Priority Date Filing Date
JP16743979A Granted JPS55113752A (en) 1978-12-22 1979-12-22 Novel compound containing peptidisyl or aminoacyl residue bonded to lipophilic group and pharmaceutic composition containing it

Country Status (4)

Country Link
US (1) US4335111A (enExample)
EP (1) EP0013856B1 (enExample)
JP (1) JPS55113752A (enExample)
DE (1) DE2965017D1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4725582A (en) * 1978-11-14 1988-02-16 Fujisawa Pharmaceutical Company, Ltd. Peptide, process for preparation thereof and use thereof
FR2460288A1 (fr) * 1979-06-29 1981-01-23 Rhone Poulenc Ind Nouveaux dipeptides, leur preparation et les medicaments qui les contiennent
FR2460290A1 (fr) * 1979-06-29 1981-01-23 Rhone Poulenc Ind Nouveaux tetra- ou pentapeptides, leur preparation et les medicaments qui les contiennent
FR2460289A1 (fr) * 1979-06-29 1981-01-23 Rhone Poulenc Ind Nouveaux tripeptides, leur preparation et les medicaments qui les contiennent
EP0204775A4 (en) * 1984-12-14 1989-10-04 Univ Trobe INHIBITOR OF AMINO ACIDS AND PEPTIDES OF HUMAN LEUCOCYTIC ELASTASE.
MX9301789A (es) * 1992-04-03 1993-10-01 Iaf Biochem Int Nuevos oligopeptidos lipofilicos con actividad inmunomoduladora.
US8563009B2 (en) * 2007-06-29 2013-10-22 Statens Serum Institut Use of monomycolyl glycerol (MMG) as an adjuvant
EP2047860A1 (en) * 2007-10-12 2009-04-15 Centre National De La Recherche Scientifique (Cnrs) Phamaceutical compositons comprosing actinomycete glycerol acyl derivatives antigens, their process of extractin, and their use against tuberculosis.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL298877A (enExample) * 1900-01-01
FR2343484A1 (fr) * 1976-03-10 1977-10-07 Anvar Le 2- (2-acetamido-2-deoxy-3-o-d-glucopyranosyl) -d-propionyl-l-alanyl-d- (a-methylamide)-glutamique et medicaments le contenant
CH636887A5 (en) * 1976-04-26 1983-06-30 Syntex Inc Process for the preparation of novel immunological adjuvant compounds
GB1563561A (en) * 1976-06-23 1980-03-26 Daiichi Seiyaku Co Muramyldipeptide derivatives and process for the preparation thereof
FI66878C (fi) 1978-02-24 1984-12-10 Ciba Geigy Ag Foerfarande foer framstaellning av nya antigenderivat

Also Published As

Publication number Publication date
DE2965017D1 (en) 1983-04-14
EP0013856B1 (en) 1983-03-09
US4335111A (en) 1982-06-15
JPS55113752A (en) 1980-09-02
EP0013856A1 (en) 1980-08-06

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