JPH0121811B2 - - Google Patents
Info
- Publication number
- JPH0121811B2 JPH0121811B2 JP10378282A JP10378282A JPH0121811B2 JP H0121811 B2 JPH0121811 B2 JP H0121811B2 JP 10378282 A JP10378282 A JP 10378282A JP 10378282 A JP10378282 A JP 10378282A JP H0121811 B2 JPH0121811 B2 JP H0121811B2
- Authority
- JP
- Japan
- Prior art keywords
- colon
- pretreatment
- magnesium citrate
- laxative
- present
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- PLSARIKBYIPYPF-UHFFFAOYSA-H trimagnesium dicitrate Chemical compound [Mg+2].[Mg+2].[Mg+2].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O PLSARIKBYIPYPF-UHFFFAOYSA-H 0.000 claims description 19
- 229960005336 magnesium citrate Drugs 0.000 claims description 18
- 239000004337 magnesium citrate Substances 0.000 claims description 18
- 235000002538 magnesium citrate Nutrition 0.000 claims description 18
- 239000008141 laxative Substances 0.000 claims description 14
- 229960005077 sodium picosulfate Drugs 0.000 claims description 14
- GOZDTZWAMGHLDY-UHFFFAOYSA-L sodium picosulfate Chemical compound [Na+].[Na+].C1=CC(OS(=O)(=O)[O-])=CC=C1C(C=1N=CC=CC=1)C1=CC=C(OS([O-])(=O)=O)C=C1 GOZDTZWAMGHLDY-UHFFFAOYSA-L 0.000 claims description 14
- 230000002475 laxative effect Effects 0.000 claims description 12
- 210000001072 colon Anatomy 0.000 description 12
- 239000000243 solution Substances 0.000 description 9
- 210000003405 ileum Anatomy 0.000 description 7
- 239000007864 aqueous solution Substances 0.000 description 6
- 210000001815 ascending colon Anatomy 0.000 description 6
- 210000004534 cecum Anatomy 0.000 description 6
- 238000000034 method Methods 0.000 description 6
- 210000000664 rectum Anatomy 0.000 description 6
- 210000001731 descending colon Anatomy 0.000 description 5
- 235000005911 diet Nutrition 0.000 description 5
- 230000037213 diet Effects 0.000 description 5
- 239000007788 liquid Substances 0.000 description 5
- 210000001599 sigmoid colon Anatomy 0.000 description 5
- 210000003384 transverse colon Anatomy 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- 238000012084 abdominal surgery Methods 0.000 description 4
- 230000003902 lesion Effects 0.000 description 4
- 208000011231 Crohn disease Diseases 0.000 description 3
- 206010022699 Intestinal stenosis Diseases 0.000 description 3
- 210000003608 fece Anatomy 0.000 description 3
- 239000011521 glass Substances 0.000 description 3
- 208000019399 Colonic disease Diseases 0.000 description 2
- 206010012735 Diarrhoea Diseases 0.000 description 2
- 241000792859 Enema Species 0.000 description 2
- 208000031481 Pathologic Constriction Diseases 0.000 description 2
- 244000269722 Thea sinensis Species 0.000 description 2
- TZCXTZWJZNENPQ-UHFFFAOYSA-L barium sulfate Chemical compound [Ba+2].[O-]S([O-])(=O)=O TZCXTZWJZNENPQ-UHFFFAOYSA-L 0.000 description 2
- 235000021152 breakfast Nutrition 0.000 description 2
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 2
- 239000002872 contrast media Substances 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 239000007920 enema Substances 0.000 description 2
- 229940095399 enema Drugs 0.000 description 2
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 2
- 210000002429 large intestine Anatomy 0.000 description 2
- 229940125722 laxative agent Drugs 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 208000014081 polyp of colon Diseases 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- XKZQKPRCPNGNFR-UHFFFAOYSA-N 2-(3-hydroxyphenyl)phenol Chemical compound OC1=CC=CC(C=2C(=CC=CC=2)O)=C1 XKZQKPRCPNGNFR-UHFFFAOYSA-N 0.000 description 1
- 208000004998 Abdominal Pain Diseases 0.000 description 1
- KHOITXIGCFIULA-UHFFFAOYSA-N Alophen Chemical compound C1=CC(OC(=O)C)=CC=C1C(C=1N=CC=CC=1)C1=CC=C(OC(C)=O)C=C1 KHOITXIGCFIULA-UHFFFAOYSA-N 0.000 description 1
- 206010009900 Colitis ulcerative Diseases 0.000 description 1
- 206010009944 Colon cancer Diseases 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 235000019501 Lemon oil Nutrition 0.000 description 1
- 206010028813 Nausea Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 1
- 201000006704 Ulcerative Colitis Diseases 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 229960004543 anhydrous citric acid Drugs 0.000 description 1
- 201000010838 ascending colon cancer Diseases 0.000 description 1
- 229960000503 bisacodyl Drugs 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 230000000112 colonic effect Effects 0.000 description 1
- 208000029742 colonic neoplasm Diseases 0.000 description 1
- 238000002052 colonoscopy Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 210000003736 gastrointestinal content Anatomy 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 208000002551 irritable bowel syndrome Diseases 0.000 description 1
- 239000010501 lemon oil Substances 0.000 description 1
- 239000006193 liquid solution Substances 0.000 description 1
- ZLNQQNXFFQJAID-UHFFFAOYSA-L magnesium carbonate Chemical compound [Mg+2].[O-]C([O-])=O ZLNQQNXFFQJAID-UHFFFAOYSA-L 0.000 description 1
- 239000001095 magnesium carbonate Substances 0.000 description 1
- 229910000021 magnesium carbonate Inorganic materials 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000008693 nausea Effects 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 230000009965 odorless effect Effects 0.000 description 1
- 235000021395 porridge Nutrition 0.000 description 1
- 229910000028 potassium bicarbonate Inorganic materials 0.000 description 1
- 235000015497 potassium bicarbonate Nutrition 0.000 description 1
- 239000011736 potassium bicarbonate Substances 0.000 description 1
- TYJJADVDDVDEDZ-UHFFFAOYSA-M potassium hydrogencarbonate Chemical compound [K+].OC([O-])=O TYJJADVDDVDEDZ-UHFFFAOYSA-M 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000008213 purified water Substances 0.000 description 1
- 229940124513 senna glycoside Drugs 0.000 description 1
- 229930186851 sennoside Natural products 0.000 description 1
- IPQVTOJGNYVQEO-KGFNBKMBSA-N sennoside A Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=CC=CC2=C1C(=O)C1=C(O)C=C(C(O)=O)C=C1[C@@H]2[C@H]1C2=CC(C(O)=O)=CC(O)=C2C(=O)C2=C(O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O3)O)C=CC=C21 IPQVTOJGNYVQEO-KGFNBKMBSA-N 0.000 description 1
- 229910052938 sodium sulfate Inorganic materials 0.000 description 1
- 235000011152 sodium sulphate Nutrition 0.000 description 1
- 235000014347 soups Nutrition 0.000 description 1
- 230000036262 stenosis Effects 0.000 description 1
- 208000037804 stenosis Diseases 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 230000009967 tasteless effect Effects 0.000 description 1
- 210000002438 upper gastrointestinal tract Anatomy 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10378282A JPS58222020A (ja) | 1982-06-18 | 1982-06-18 | 前処置用下剤 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10378282A JPS58222020A (ja) | 1982-06-18 | 1982-06-18 | 前処置用下剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS58222020A JPS58222020A (ja) | 1983-12-23 |
| JPH0121811B2 true JPH0121811B2 (enrdf_load_stackoverflow) | 1989-04-24 |
Family
ID=14362979
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP10378282A Granted JPS58222020A (ja) | 1982-06-18 | 1982-06-18 | 前処置用下剤 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS58222020A (enrdf_load_stackoverflow) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10092573B2 (en) | 2010-12-13 | 2018-10-09 | Salix Pharmaceuticals, Inc. | Gastric and colonic formulations and methods for making and using them |
-
1982
- 1982-06-18 JP JP10378282A patent/JPS58222020A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS58222020A (ja) | 1983-12-23 |
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