JPH01211529A - Drug containing chitin or chitosan compound as base material - Google Patents

Abstract

PURPOSE:To obtain a drug, consisting of a chitin or chitosan compound in the form of an organic acid additive, enzymic hydrolyzate, N-acylated derivative, alkylated derivative, etc., and useful as a drug good for the stomach and bowels, healthy food, hair tonic, freshness retaining agent, etc. CONSTITUTION:A drug consisting of a high-viscosity liquid obtained by adding water to antimicrobial UME (plum) flesh extract, fruit extract, ascorbic acid of vitamin C, citric acid, tartaric acid, etc., mixing and dissolving chitin or chitosan powder, a dispersion prepared by mixing and dissolving sodium alignate and green lavers therein, a solution of dispersion obtained by adding and dispersing an alcohol and glycerol therein, a pasty liquid obtained by mixing and masticating the dispersion, adding, as necessary, sorbic acid, licorice, etc., thereto, and a pasty liquid containing a small amount of a radioactive inorganic salt and metallic salt and further beer fermentation refuse, defatted soybean flour, etc., and masticating the resultant mixture, a liquid prepared by hydrolyzing with an enzyme, such as chitosanase or lysozyme, or adding an N-acylated, alkylated or etherified liquid thereto or prepared and tableted or prepared chitin or chitosan compound.

Description

[Detailed Description of the Invention] This invention provides a solid powder in which chitin and chitosan are ingested and applied on their own, which causes indigestion and is difficult to apply. Dissolved highly viscous pastes and water-alcohol mixtures, solid tablets that are easily digested and absorbed by enzyme hydrolysis, acylated products, alkylated and etherified chitin, chitosan liquid mixtures, sodium alginate, and seaweeds such as acrolla and seaweed. , sabonin, carrot juice, sorbitic acid, dehydroacetic acid, bud preservatives, sweeteners, and acid adjustment by adding radiation-promoting inorganic mineral components, and high viscosity with tungstic acid soda added. aqueous liquid or paste, defatted soybean flour, beer fermented shibori lees powder,
Chitin, chitotin compounds, and freshness-preserving agents, which are made by tabletting a mixture of powders such as coffee grounds powder, starch milk powder, etc., and processing the granulated powder into health foods, health drugs, and beverages. It depends on development. Generally known chitin is a polysaccharide in which N-acetol-D-bulcosamine is bound to B1.4, and it is made up of 20-70% of the carapace of crabs, shrimps, krill insects, etc., and the bacterial vesicle membrane of mushrooms. It is a depcetylated product. As a fiber component of biological tissue, it coexists with filler components such as calcium carbonate and protein. The raw material for this chitin is the biomass carapace of many crabs, krill, and prawns, and chitin can be obtained by decalcifying this carapace with dilute acid and then deproteinizing it with dilute alkali. Furthermore, when this chitin is treated with a concentrated alkali and N-deacetylated, chitosan is produced. That is, the molecular structure of chitin and chitosan is as follows.

This chitin and chitosan are dissolved in rational acids or N long-chain alkyls charged with cations of quaternary ammonium salts.
Chitosan derivatives exhibit antibacterial properties against Fusarium oncogenic bacteria and Escherichia coli, and are useful as antibacterial properties for preserving the freshness of vegetables and fruits.In addition, when chitin and chitosan powder are taken, they have an antibacterial property that inhibits the growth of gas cells. It is attracting attention as a strengthening substance.

However, feeding animals generally do not digest chitin and chitosan, but when mixed with the feed of 20-day-old mice,
It has the effect of preventing the accumulation of cholesterol and fatty acids in the body.
In particular, chitosan is generally less toxic than low-cholesterol agents and is also a promising drug. In addition, chitosan's peptide muraminan is not digested, but forms a complex with cholesterol and fatty acid toxic metal ions, which are excreted from the body.In addition, it has antacid and digestive and absorption-enhancing effects, and it also acts as an antacid and promotes digestion and absorption in the intestines of humans and infants. Bifidobacterium, an endobacteria, uses N-acetyl B as a nutritional source.
．． P. Requires grecosaminade.

Furthermore, chitin and chitosan oligomers can be used as additives in infant milk and food for sick people to promote the growth of intestinal bifidobacteria. It is also used as a carrier for aspirin, as a useful plant elicitor, and as a self-protective agent.

In addition, alkylated products are used as raw materials for cosmetics,
Acylated products are used, but when used in conjunction with radiation-active calcium carbonate, magnesium carbonate, bentonite, and zeolite, it can be used as a base for cosmetics to improve the spread and adhesion of cosmetics.

In addition, alkylated and acylated products are often used as raw materials for cosmetics, and products to which ascorbic acid and vitamins are added give the skin a healthy color. or,
Sulfonated chitin is useful as an antithrombotic agent. It is used as an ammonia salt to prevent continuous cropping damage.

However, when humans ingest chitin and chitosan, it is difficult for the human body to digest them, resulting in alkylation,
Since coasting is expensive for acylation, we aim to reduce the coasting cost by treating it with easily soluble organic acids or by enzymatic decomposition.
When dissolved with ascorbic acid, citric acid, succinic acid, fumaric acid, etc., the antibacterial properties inherent in plum meat extract and the antibacterial properties of N long-chain alkyl derivatives charged with cations of quaternary ammonia salts of chitin and chitosan are combined. It exerts a synergistic effect, and also transports and exhibits antibacterial properties by its carrier action, so it can prevent damage to the gastrointestinal wall that occurs when taken alone, such as creosote or Astragalus, by forming a protective wall. It prevents this and has a delayed effect. In particular, this mixed solution of chitin and chitosan protects against gastrointestinal disorders when directly using concentrated powders such as vitamin C, making it safe.

In addition, when radiation-prone calcium carbonate is added to the organic acid solution of chitin and chitosan, carbon dioxide gas is generated.
When calcium carbonate contains trace amounts of platinum metals, ions of Kinagako, rare metals, uranium, radium, germanium selenium, etc., it further enhances its antibacterial properties and improves its antibacterial properties to some extent. When adjusted to the acidic side, the calcium salt becomes easily soluble in aqueous fluids and is easily absorbed into the body.Especially when reacting with amino acids, calcium has the advantage of being easily absorbed even outside the duodenal intestine. Particularly anti-cancer.

In particular, when using plant aloe juice, cactus juice, or calcium salts from cactus, etc., hair nourishing agents such as egg yolk oil, camellia oil, surfactants, nitroguaiacol, thioallyl compounds, alcohol, glycerin flavoring, bitter tincture, etc. should be mixed. This makes the hair-nourishing effect even higher.

The effect of this hair tonic is that graying of hair is caused by the formation of an air-embedded layer on the surface of the hair surface, which becomes a diffusely reflective surface when light hits it, and this is coated with chitin and chitosan dissolved matter. The anti-acid effect is caused by the formation of a gel-like film on the hair surface that is deoxidized by washing with water. In particular, chitin-chitosan dissolved in plum meat extract has a blackish-brown color, so it has black dyeing properties and also retains a hair-nourishing effect.

When it contains calcium salts and iron salts, it stimulates the keratin, promotes stimulation to the surface of the hair bulb, and makes it easier to grow hair, and when combined with egg yolk oil, it increases the amount of organic acid dissolved. When adding sodium tungstic acid or potassium, it forms a condensed acid of tungstic acid, which first coagulates the tumor decomposition products to form a purifying wall on the tumor-injured surface of the gastrointestinal wall, and further purifies the gastrointestinal wall. However, direct administration of sodium tungstate water has the effect of alleviating and preventing intestinal obstruction caused by hardening of the gastrointestinal wall through the formation of chitin and chitosan films. In addition, radiation-promoting sodas and those to which calcium is added have the effect of maintaining antibacterial properties, and not only have a higher concentration of rare earth platinum gold, silver, and copper ions, but also have anticancer properties.

In addition, kelp, seaweed, wakame, green seaweed, pectin, and sodium alginate are dissolved and dispersed in an organic acid concentrated solution of chitin and chitosan to produce powders such as starch, protein, carboxymethyl fiber, bran, defatted soybean flour, coffee grounds, and tea powder. When making solid tablets by mixing beer fermentation lees powder, it is possible to make drugs that are easy to swallow, and chitin and chitosan are useful as glue agents. In particular, when aldehyde is added, it has the property of gelling, and has the effect of curing with polyviale alcohol and acetal brioxal, increasing adhesive strength.
In addition, when used in combination with sodium alginate, it can be used as an additive for hair nourishing agents to strengthen its adhesion.

Figure 7 clarifies the explanation of this hair tonic, and shows that a long hair grows at the top of the hair bulb, and the outer surface of this hair 1c is an outer sheath surface, and the inner sheath 2c is at its core. This lower part contacts the inside of the hair bulb plate 3c and absorbs nutrients, but the reason why the hair turns gray is because this outer sheath surface 4c has many holes that form air holes and absorb light. On the other hand, it reflects diffusely and looks like gray hair. However, when a dissolved substance of chitin or chitosan is applied to the air pores of these cracks to form the coating 5c, the hair appears blackish brown and the capillary absorption of the inner sheath fluid is smoothly carried out from the bottom, resulting in physical It is also effective. That is, capillary absorption becomes more likely to occur. And hair grows more easily. or,
When the PH value of the radiation-promoting calcium salt is 7.4, the stimulation to the stratum corneum of keratin increases, and it has the effect of promoting destruction of the epidermis of the hair bulb and making it germinable.

Next, when a polyvinyl acetal solution is mixed with a chitin or chitosan solution, water resistance is increased, and when glycol is added, miscibility is increased. In addition, egg yolk oil contains a large amount of restin and has the property of nourishing the stratum corneum, softening it, and expanding the capsule surface of the hair bulb.

Next, when an aldehyde is added to the organic acid solution of chitin-chitosan and a polyacetal resin is added, the aldehyde causes gelation, which helps strengthen the coating and increases water resistance.

Also, when a compound having an allyl group such as camellia oil or garlic is mixed with zotamine B1B2, it is effective as a hair growth promoter as well as a bitter tincture stimulant. Furthermore, the chitin-chitosan solution of lactic acid is useful as a carrier of nutrients for hair growth due to the permeability of lactic acid.

Furthermore, when washing with water after application, it is more effective than known nonces. Also, B. After the propiolactonized chitosan is treated with lactic acid, it is treated with an alkali to remove the B propion lactone decomposition product, and the B. The B-propiolactonized chitosan film reacted with propionlactone has high cancer sensitivity and decreases impedance, so it becomes active in hair growth. Especially those containing lithium chloride have good properties.

In addition, chitin and chitosan can be decomposed by the enzymes lysozyme and chitinase chitosanase, and the hydrolysis concentration can be freely controlled depending on the chemical structure of the O-alkyl group and N-acyl group of the substrate, allowing them to be digested and absorbed within animal tissues. be done. It is also used as an anti-cancer drug and as a hormone concentrate.

In addition, O-disulfated N-acetyl chitosan has an anticoagulant activity that is approximately twice that of heparin, and an activity that is released into the blood by lipoprotein lipase that is 0.1 times that of heparin. It is useful as an anticoagulant because it reduces the concentration of free fatty acids in the blood. Also, the reduction in cholesterol is 2-5
% of rat and chicken feed increases plasma cholesterol levels by 0.6 to 0.7 times, liver cholesterol by 0.5 times, chickens by 0.6 times, and rabbits by 0.3 times.
Chitin and chitosan decomposed products, which have been reduced twice as much and are enzymatically decomposed, have antibacterial properties against black spot bacteria and Escherichia coli.

In addition, chitin and chitosan have the effect of protecting the skin from the harmful effects of other cosmetics due to carboquine methylation, so if they are appropriately added to hair tonics, good results can be obtained.

In addition, chitin and chitosan are dissolved in ascorbic acid and boric acid, and Hotsukostar fungicide is added to dilute to 30% to produce melons, melons, mandarin oranges, Chinese cabbage, cabbage, tomatoes, etc.
When applied to cut ends of grapes, etc., it prevents black discoloration and is effective for long-term preservation. As mentioned above, the dissolved products of chitin, chitosan, and their derivatives can be used as a protective film and
As a carrier or by derivatizing it, it is absorbed directly into the body and acts very effectively, and the development using it as a raw material is an industrially useful invention.

The implementation of this invention will be explained as follows with reference to the drawings. In Figure 1, chitin and chitosan powder are put into the stainless steel container of the dissolution tank 5 from the tank 4, and the dissolving solution is also put in from the tank 3, and steam is put in from the boiler 1 to heat it and dissolve it and disinfect it. After that, the medicine is further mixed in the mixer 11 through the pipe (6), and conveyed by the belt conveyor, and the mixed medicine liquid is introduced into the bottling machine 13, sealed, labeled and packaged. and send the money.

The containers and bottles are also sterilized during the process to make them sterile before culturing.

On the other hand, the chitin and chitosan solution in the pipe (6) was sent to the mixer (7) by a pump, and the additives were introduced into the mixer from the tank 9.10. , it is molded by a tablet making machine 16, weighed, and packaged.

FIG. 2 shows a front view of a drink container containing a mixture of chitin and chitosan organic acid drugs, and FIG. 3 is a side view taken along the line A-B. This colored glass bottle 1a is placed in a bottle filling machine 13, sealed, and heat-treated in a heat sterilizer 13b for packaging.
A label 4a is pasted on the surface of the bottle 1a, 200 cc of highly viscous liquid drink 3a is poured into the bottle, and the bottle is sealed and packaged with a stopper 2a.

Figure 4 shows that an antibacterial agent is made by mixing plum meat extract, chitin ascorbate, chitosan dissolved matter with radiation calcium carbonate and the same soda potash extract, and ascacorbate chitin chitosan dissolved matter with radiation calcium salt and the same soda potash salt. .

This antibacterial agent 9a is put into a sterilized plastic or glass ceramic container 6a, and the antibacterial agent M is screwed together with the upper lid 5a.
Fig. 5 shows a side view of a plastic or metal tube 8a in which a drug was masticated with a chitin-chitosan organic acid solution, an enzymatically decomposed chitin, a chitosan compound, a carboquine methylated chitin, or a chitosan derivative. Things,
That is, the paste 9a is placed in a tube and the bottom is sealed, and the upper part of the tube 8a is widened toward the end, and a cap 10a is screwed onto the upper part to seal it. As shown in the figure, this tube is also filled with food additives and drug paste for commercialization.

FIG. 5 shows a side view in which a powder or tablet 13a containing a chitosan-chitin paste compound and a drug mixture is introduced through the opening 14a, the pressure is reduced to vacuum, and the inert gas is sealed. 1st
Figure 0 shows the freshness retention characteristics of lettuce, and Figure 11 shows the freshness retention characteristics of melon.

Further, FIG. 7 is a side view of a lettuce 15a having a freshness-preserving agent 16b coated on the root cut 16a of the lettuce 15a and wrapped with a packaging plastic film 17a, and FIG. 8 is a side view of a melon 18a. The side view is shown, and films of chitin and chitosan compounds 16a and 16a' are applied to m and n of the cutting end 19a of the melon, and a mixed solution 16 of chitin and chitosan compounds is also applied to the navel 2aa at the bottom of the melon 18a.
Apply a, dry and package.

A solution of chitosansielac and a bactericidal agent is applied to this surface to form a film 21a. And then wrap it.

In the freshness-keeping characteristics of lettuce shown in Figure 10, A shows the lettuce cut without coating, B shows the cut of lettuce coated with only the chemical solution, and C shows the cut of lettuce coated with the freshness-keeping agent of the present invention, which is a mixture of chitin and chitosan. , showing excellent results of antibacterial properties of chitin-chitosan compounds.

Figure 11 shows the freshness-keeping characteristics of melons, where A' is untreated, B' is melon coated with a freshness-preserving agent that does not contain chitin or chitosan, and C' is melon containing the present invention. , the increase in sugar content is suppressed. Furthermore, after 20 days, the number of grape grains that were applied to the cut ends of grapes fell off was 38% when shaken and vibrated, and the number of grape grains that fell off was 8% for the product that was applied in the present application. In the case of tomatoes, by coating the surface of the tomato with Sierrac chitosan compound liquid and then applying it to the cut end, there is no rotting even after 3 months at room temperature of 20 degrees Celsius, and chitin chitosan is treated with enzymes. The decomposed water solution is sterilized by boiling once and then applied with a mixture of Sierrac, Monozurin, alcohol, and ammonia water sterilizer.

Next, an example of this formulation is as follows.

Example (1) Tomato freshness preservation agent Sierrac, chitosan solution 110g Monoporin 2g Alcohol 200g Ammonia water 200g Hoxter fungicide 0.5g Example (2) Lettuce freshness preservation agent chitin, chitosan solution 5% sel, 1000g Ascorbic acid, plum Meat extract or 0.3g to 3g Boric acid 6g Example (3) Freshness preservation N long chain alkyl chitosan derivative 3g Chitosan ascorbic acid water 2:4:14 20g Disinfectant Foster or demodroacetic acid 0.1g This N long chain alkyl chitosan derivative The molecular structure of is as follows.

Example (2) of this freshness preserving agent results in characteristics shown in FIG. In Example (3), the characteristics of melon are shown in FIG.

Example (4) Radiation Bentonite, an agent for preventing continuous cropping damage 100g N long-chain alkyl chitosan derivative 3g Chitin chitosan lactic acid aqueous solution 0.1g Chitin chitotin powder 5g Chitinase, Kiresanase, Lysozyme enzyme 0.1g Example (5) Radiation, an agent for preventing continuous cropping damage Zeolite 100g N-Alylidene, N-Alkylidene Chitosan or N-Carboxymethyl Chitosan 1.0g Chitin Chitosan Ascorbic Acid Water 4.0g Chitin, Chitosan Powder 5g Enzyme 0.1g Organic Fertilizer 0-100g This inhibitor for preventing continuous cropping disorders is 10A. 150kg per
In addition, when cropping, the root weight is 2.4g, the number of leaves is 13.4, the leaf weight is 122g, the number of black knots is 0, and in example (5), the root weight is 3.4g.
The number of g leaves was 13.5, the leaf weight was 134, and the number of beds affected by cat clot was 0. This test is the result of an experiment on Chinese cabbage clubroot disease, which is a type of fungus called Plamodeophra Brassicae.

Add 1 part radiation calcium carbonate to this bentonite.
Spraying at a ratio of 1:1 gives the same result.

This result shows that in addition to Chinese cabbage, it is also effective on cabbage, lettuce, and radish, and it is also effective on tomatoes and eggplant, and adding organic fertilizer and radiation bacteria is even more effective, increasing production by 30%. In case of no treatment, root weight 1.7g and number of leaves 11.9
The leaf weight was 75g. The number of wards affected was 6, and the severity of disease was 2.5. In addition, in the case of the present application, no nekobu disease occurred even after continuous cropping three times. For tomatoes, add 100 million units of bacteria to 100 million units of water.
Quaternary ammonium salt of N-dimethyl chitosan (9,R alkyl group) N-acyl chitosan, N-
When a 0.03% aqueous solution of alkylidene and N-alkylidene chitosan is added and sprayed with a spring sprayer, black spot disease and damping-off disease are prevented by the bactericidal action. Also effective are the soda salt and ammonia salt of sulfonated chitin, glycol chitin, sulfonated chitin, dihydroquine, and propyl chitin.

Example (6) Gastrointestinal agent Plum meat extract ascorbic acid 29g Chitin, chitosan powder 7.5g Hot water 500g Radiation calcium carbonate 3g Licorice juice 10g Savonin 0.1g Example (7) Gastrointestinal regulator Chitin, chitosan ascorbic acid 10g Hot water 100
g Radiation sodium tungstate or sodium paratungstate 5g Licorice water 10g Savonin 1g Example (8) Same tablet example (6) Combination 200g Defatted soy flour or wheat flour, fermented lees powder 50g Chitin, chitosan powder Chitonase kinase 5g Alginic acid soda
5g Example (6) not only acts as a carrier for plum meat extract, but also maintains antibacterial properties for a long time, suppresses gas generation due to intestinal fermentation, and prevents diarrhea. Example (7) is for enteroma,
When taken once a day for 7 days, ascites decreases.
■ Go twice. Dosage 8mg/K for oncogenic leukemia
g/day 6.5 However, this is the number of cancer cells after 10 days. The number of normal cells was 21, and in the case of administration D, the number of cancer cells was 13.6. The ratio between the number of normal cells and the number of cancer cells was 0.98 to 1.2. The suppression of cancer cells in mice was 0 after administration of 100 kg of chitin powder. 1 with chitosan administration. 0 for bihydroquinepropyl chitin. CM, chitin, and chitosan were 0.

Example (9) Antidiarrheal agent chitin, chitosan ascorbic acid water 5g lactic acid water 2
g creosote 1g radiation calcium carbonate or bentonite 2
g Chitosan powder Sodium alginate 5g This mixture of creosote is slow-acting, but
Example of how chitin-chitosan powder protects the stomach wall without damaging it (10) Feed additives Chitin-chitosan powder Ascorbic acid water 5000g Canic acid powder Chitinase, chitonases 5000g Protease 50g Soybean germ powder 1g Compound feed 500kg Chlorella 1-2g Radiation calcium carbonate 3000g seaweed 10
0g For feed addition in Example (10), B is first mixed and made into a paste, which is mixed into 100 kg of compounded feed, and then further mixed into 400 kg of feed to make it uniform.

When this mixed feed is used as egg-raising chicken feed, the egg raising rate increases by 2%, and in the case of broilers, the mortality rate is usually 400%.
30 out of 0 birds decreased to 3 birds and weighed 25 in 70 days.
kg becomes the same weight in 60 days and there is no increase in fat.

Cholesterol is always normal and does not increase due to lack of exercise. This antithrombotic material consists of chitin,
Chitosan derivatives are optimal, and O-diacetyl chitin gives good results.

Example (11) Tomato and tangerine skin brightener shellac 10
g Alcohol 200 cc Monophoporin 10 g Ammonia water surfactant 46 g Sodium dehydroacetate 2 g Fumaric acid polyester 6 g Chitin chitosan ascorbic acid 3 g This mixture was diluted 10 times and put into a souffle conveyor, tomatoes and mandarin oranges were added, and dried. and package it. Hardness does not change even if left at room temperature of 20°C for 1 to 3 months. And Mikan's bellybutton never falls off. The shape collapsed after 2 months with only Sierra Tsuk as a brightener. In the case of mandarin oranges,
Although mold was generated, in the case of the chitin chitosan of the present application, no mold was generated.

Example (12) Bread additive radiation calcium carbonate 10g Chitin, chitosan chitinase, chitonase decomposition solution 2.5% liquid 100g Fermented yeast added small rice paste 5Kg Example (1
3) Mochi mold prevention agent Radiation calcium carbonate 1g Same as above leachate 100g Chitin, chitosan dehydroacetic acid, ascorbic acid 10
g Example (14) Hair nourishing chitin, chitosan organic acid 100g Plum meat extract 2g Egg yolk oil 4g Polyvinyl acetal or polyvinyl glyoxide 4g Radiation calcium carbonate 6g Guacacol (nitro) 0.1g Example (15) Hair nourishing shampoo with alcohol fragrance 100cc chitin chitosan chitinase, chitonase decomposition solution 2% 5
0cc Egg yolk oil 1g Surfactant 3g Allyl compound 0.1g Example (16) Beverage (cholesterol lowering) Chitin, chitosan Ascorbic acid 2% water 100g Black vinegar 5g Sugar content licorice juice 120g Alcohol 10cc Radiation calcium carbonate 1g Koshin 0.1g Use the bread additive of Example (12) in a conventional manner, masticate with small wheat flour fermentation bacteria water, add the additive at 38~40℃, cure for 24 hours to 12 hours, and then bake the bread. Even after finishing and opening the package, no green mold or white mold appeared after 7 days. This is due to the antibacterial properties of chitin and chitosan.

The tomato and tangerine brightening agent in Example (11) is generally based on Sierra Tsukuba, but the chitin-chitosan additive has less occurrence of white mold and green mold, and the results are obtained after 2 months of packaging in cardboard boxes. Of the 60 items, 8 were rotten. The rice cake of Example (18) that was sprayed onto the surface and dried did not have green mold. Examples (14) to (16)
has already been explained.

As described above, the feature of the present invention is that the antibacterial and promoting effects are exhibited by the combination of chitin and chitosan organic acid additives, and in particular, the use of chitin and chitosan in an enzymatically decomposed solution, quaternary ammonia salts, sulfates, acylated products, etc. Chitin-chitosan derivatives with active agents added or radiation inorganic salts have higher antibacterial properties and are used in a wide range of applications. Used as a carrier. In particular, when treating intestinal cancer, the addition of sodium tungstate cleanses the tumor and protects the wound.The addition of chitin and chitosan greatly reduces the risk of intestinal cancer and maintains antibacterial properties for a long time. This invention is also useful as a palliative drug and has industrial applicability.

It is also a promising development for preventing continuous cropping problems and preserving freshness.

[Brief explanation of the drawing]

Figure 1 is a process diagram of chitin-chitosan beverage and tablet processing, Figure 2
The figure is a front view of the drink bottle, Figure 3 is its A-B cut side view, Figure 4 is a side view of the hair nourishing cream, Figure 5 is chitin,
Figure 6 is a side view of a tube container containing chitosan, Figure 6 is a side view of a plastic bag, Figure 7 is a side view of lettuce packaging, Figure 8 is a side view of a tube container containing chitosan.
The figure is a side view of melon freshness maintenance, Figure 10 is the characteristics of lettuce, Figure 11 is the characteristics of melon, and Figure 9 is a side view of hair.

Claims (1)

[Claims] As described in the following text, antibacterial plum meat extract, fruit extract, grass root extract, vitamin C ascorbic acid, citric acid tartaric acid, malic acid, glutamic acid amino acid, black vinegar, lactic acid and inorganic acid are added with water. In addition, highly viscous liquid prepared by mixing and dissolving chitin-chilic acid tosan powder, dispersion liquid obtained by mixing and dissolving sodium alginate, seaweed kelp, green nori, etc., alcohol, glycol glycerin, etc. are added to dissolve and disperse it, and mixed substances are prepared. Knead it into a paste, add sorbitic acid,
Add dehydroacetic acid, licorice, sugar, and other sweeteners, and add small amounts of radiation-promoting inorganic salts such as calcium salts, magnesium salts, soda salts, potash salts, and sodium tungstate, platinum metals, gold, silver, copper, Add miso paste, beer fermentation lees, defatted soybean flour, coffee lees powder, sabonin pearl barley powder, amachazur powder, germ powder, spices, flavorings, etc. to the paste solution containing iron-containing metal salts and masticate. chitin, or a liquid prepared by adding a liquid that has been decomposed with an enzyme such as chitonase, lysozyme, or chitinase, or that has been N-acylated, alkylated, or etherified, or that has been made into a tablet.
A conditioning agent, curing agent, and freshness-preserving agent for gastrointestinal medicines, health foods, kidney storage liver blood preparations, etc. made of chitosan compounds.