JPH0119880B2 - - Google Patents
Info
- Publication number
- JPH0119880B2 JPH0119880B2 JP55039726A JP3972680A JPH0119880B2 JP H0119880 B2 JPH0119880 B2 JP H0119880B2 JP 55039726 A JP55039726 A JP 55039726A JP 3972680 A JP3972680 A JP 3972680A JP H0119880 B2 JPH0119880 B2 JP H0119880B2
- Authority
- JP
- Japan
- Prior art keywords
- glucose
- electrode
- enzyme
- immobilized
- concentration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 29
- 239000008103 glucose Substances 0.000 claims description 29
- 108010015776 Glucose oxidase Proteins 0.000 claims description 23
- 239000004366 Glucose oxidase Substances 0.000 claims description 23
- 229940116332 glucose oxidase Drugs 0.000 claims description 23
- 235000019420 glucose oxidase Nutrition 0.000 claims description 23
- 102000004190 Enzymes Human genes 0.000 claims description 19
- 108090000790 Enzymes Proteins 0.000 claims description 19
- 229940088598 enzyme Drugs 0.000 claims description 19
- 239000012528 membrane Substances 0.000 claims description 17
- 102000020006 aldose 1-epimerase Human genes 0.000 claims description 14
- 108091022872 aldose 1-epimerase Proteins 0.000 claims description 14
- 108010093096 Immobilized Enzymes Proteins 0.000 claims description 10
- 239000002131 composite material Substances 0.000 claims description 10
- 238000006911 enzymatic reaction Methods 0.000 claims description 4
- 239000000126 substance Substances 0.000 claims description 4
- 150000001875 compounds Chemical class 0.000 claims description 3
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 32
- 230000004044 response Effects 0.000 description 18
- 238000000034 method Methods 0.000 description 8
- 238000006243 chemical reaction Methods 0.000 description 7
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 7
- AZQWKYJCGOJGHM-UHFFFAOYSA-N 1,4-benzoquinone Chemical compound O=C1C=CC(=O)C=C1 AZQWKYJCGOJGHM-UHFFFAOYSA-N 0.000 description 6
- QIGBRXMKCJKVMJ-UHFFFAOYSA-N Hydroquinone Chemical compound OC1=CC=C(O)C=C1 QIGBRXMKCJKVMJ-UHFFFAOYSA-N 0.000 description 6
- 238000005259 measurement Methods 0.000 description 6
- 230000035945 sensitivity Effects 0.000 description 6
- WQZGKKKJIJFFOK-DVKNGEFBSA-N alpha-D-glucose Chemical compound OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-DVKNGEFBSA-N 0.000 description 5
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 5
- 230000007423 decrease Effects 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 229910052760 oxygen Inorganic materials 0.000 description 5
- 239000001301 oxygen Substances 0.000 description 5
- 239000000243 solution Substances 0.000 description 5
- 239000012086 standard solution Substances 0.000 description 5
- 239000004809 Teflon Substances 0.000 description 4
- 229920006362 Teflon® Polymers 0.000 description 4
- 239000007853 buffer solution Substances 0.000 description 4
- 230000003647 oxidation Effects 0.000 description 4
- 238000007254 oxidation reaction Methods 0.000 description 4
- 229910052697 platinum Inorganic materials 0.000 description 4
- 230000009471 action Effects 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 230000009467 reduction Effects 0.000 description 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- PHOQVHQSTUBQQK-SQOUGZDYSA-N D-glucono-1,5-lactone Chemical compound OC[C@H]1OC(=O)[C@H](O)[C@@H](O)[C@@H]1O PHOQVHQSTUBQQK-SQOUGZDYSA-N 0.000 description 2
- SXRSQZLOMIGNAQ-UHFFFAOYSA-N Glutaraldehyde Chemical compound O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 description 2
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 229910052799 carbon Inorganic materials 0.000 description 2
- 239000000975 dye Substances 0.000 description 2
- 229960003681 gluconolactone Drugs 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 239000008363 phosphate buffer Substances 0.000 description 2
- 239000012085 test solution Substances 0.000 description 2
- 230000008901 benefit Effects 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 229920002301 cellulose acetate Polymers 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 238000004132 cross linking Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- ZOMNIUBKTOKEHS-UHFFFAOYSA-L dimercury dichloride Chemical class Cl[Hg][Hg]Cl ZOMNIUBKTOKEHS-UHFFFAOYSA-L 0.000 description 1
- 238000002848 electrochemical method Methods 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- RSAZYXZUJROYKR-UHFFFAOYSA-N indophenol Chemical compound C1=CC(O)=CC=C1N=C1C=CC(=O)C=C1 RSAZYXZUJROYKR-UHFFFAOYSA-N 0.000 description 1
- 239000011259 mixed solution Substances 0.000 description 1
- 150000003057 platinum Chemical class 0.000 description 1
- -1 potassium ferricyanide Chemical compound 0.000 description 1
- 230000004043 responsiveness Effects 0.000 description 1
- ANRHNWWPFJCPAZ-UHFFFAOYSA-M thionine Chemical compound [Cl-].C1=CC(N)=CC2=[S+]C3=CC(N)=CC=C3N=C21 ANRHNWWPFJCPAZ-UHFFFAOYSA-M 0.000 description 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3972680A JPS56137899A (en) | 1980-03-27 | 1980-03-27 | Determining method of glucose concentration |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3972680A JPS56137899A (en) | 1980-03-27 | 1980-03-27 | Determining method of glucose concentration |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS56137899A JPS56137899A (en) | 1981-10-28 |
| JPH0119880B2 true JPH0119880B2 (ko) | 1989-04-13 |
Family
ID=12560978
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP3972680A Granted JPS56137899A (en) | 1980-03-27 | 1980-03-27 | Determining method of glucose concentration |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS56137899A (ko) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6024444A (ja) * | 1983-07-19 | 1985-02-07 | Matsushita Electric Ind Co Ltd | バイオセンサ |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4973193A (ko) * | 1972-09-28 | 1974-07-15 | ||
| JPS5236092A (en) * | 1975-09-17 | 1977-03-19 | Omron Tateisi Electronics Co | Measuring electrode |
| JPS5258995A (en) * | 1975-11-07 | 1977-05-14 | Owens Illinois Inc | Measuring method and apparatus for glucose |
-
1980
- 1980-03-27 JP JP3972680A patent/JPS56137899A/ja active Granted
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4973193A (ko) * | 1972-09-28 | 1974-07-15 | ||
| JPS5236092A (en) * | 1975-09-17 | 1977-03-19 | Omron Tateisi Electronics Co | Measuring electrode |
| JPS5258995A (en) * | 1975-11-07 | 1977-05-14 | Owens Illinois Inc | Measuring method and apparatus for glucose |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS56137899A (en) | 1981-10-28 |
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